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FIG.\t1.8\nSummary\tof\tfat\tabsorption.\nAt\tthe\tsurface\tof\tthe\t\nunstirred\twater\tlayer\t(UWL),\n\tthe\tslightly\tacidic\tand\twatery\tplate\tthat\nforms\ta\tboundary\tbetween\tthe\tintestinal\tlumen\tand\tthe\tbrush\tborder\tmembranes,\tthe\tlipids\tdetach\nfrom\tthe\tmicelles.\tRemnants\tof\tthe\tmicelles\treturn\tto\tthe\tlumen\tfor\tfurther\ttransport.\tThe | [
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the\tenterocyte.\tCurrent\ttheories\tindicate\tthat\tboth\tpassive\tdiffusion\tand\tcarrier-mediated\nmechanisms\tcontribute\n\tto\tlipid\tabsorption.\tAt\tlow\tfatty\tacid\tconcentrations,\tcarrier-mediated\nmechanisms\ttake\tprecedence\twith\tlittle\tpassive\tdiffusion\toccurring.\tHowever,\twhen\tfree\tfatty\tacid | [
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] |
concentration\tin\tthe\tintestinal\tlumen\tis\thigh,\tabsorption\tof\tfatty\tacids\tvia\tpassive\tdiffusion\tbecomes\nquantitatively\timportant.\nIn\tthe\tenterocyte,\tthe\tfatty\tacids\tand\tmonoglycerides\tare\treassembled\tinto\tnew\ttriglycerides.\nOthers\n\tare\tfurther\tdigested\tinto\tfree\tfatty\tacids\tand\tglycerol\tand\tthen\treassembled\tto\tform | [
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triglycerides.\tThese\ttriglycerides,\talong\twith\tcholesterol,\tfat-soluble\tvitamins,\tand\tphospholipids,\tare\nsurrounded\tby\ta\tlipoprotein\tcoat,\tforming\tchylomicrons\t(see\t\nFig.\t1.8\n).\tThe\tlipoprotein\tglobules\tpass\ninto\tthe\tlymphatic\tsystem\tinstead\tof\tentering\tportal\tblood\tand\tare\ttransported\tto\tthe\tthoracic\tduct\nand\temptied | [
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repackaged\tinto\tvery-low-density\tlipoproteins\tand\ttransported\tprimarily\tto\tthe\tadipose\ttissue\tfor\nmetabolism\tand\tstorage.\nUnder\tnormal\tconditions\tapproximately\t95%\tto\t97%\tof\tingested\tfat\tis\tabsorbed\tinto\tlymph\tvessels.\nBecause\tof\ttheir\tshorter\tlength\tand\tthus\tincreased\tsolubility,\tfatty\tacids\tof\t8\tto\t12\tcarbons\t(i.e., | [
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medium-chain\tfatty\tacids)\tcan\tbe\tabsorbed\tdirectly\tinto\tcolonic\tmucosal\tcells\twithout\tthe\tpresence\nof\tbile\tand\tmicelle\tformation.\tAfter\tentering\tmucosal\tcells,\tthey\tare\table\tto\tgo\tdirectly\twithout\nesterification\n\tinto\tthe\tportal\tvein,\twhich\tcarries\tthem\tto\tthe\tliver. | [
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] |
into\tthe\tportal\tvein,\twhich\tcarries\tthem\tto\tthe\tliver.\nIncreased\tmotility,\tintestinal\tmucosal\tchanges,\tpancreatic\tinsufficiency,\tor\tthe\tabsence\tof\tbile\tcan\ndecrease\tthe\tabsorption\tof\tfat.\tWhen\tundigested\tfat\tappears\tin\tthe\tfeces,\tthe\tcondition\tis\tknown\tas\nsteatorrhea\t(see\t\nChapter\t27 | [
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long;\tMCTs\tare\tclinically\tvaluable\tfor\tindividuals\n\twho\tlack\tnecessary\tbile\tsalts\tfor\tlong-chain\tfatty\nacid\tmetabolism\tand\ttransport.\tSupplements\tfor\tclinical\tuse\tnormally\tare\tprovided\tin\tthe\tform\tof\toil\nor\ta\tdietary\tbeverage\twith\tother\tmacronutrients\tand\tmicronutrients.\nVitamins\tand\tminerals | [
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] |
Vitamins\tand\tminerals\nVitamins\tand\tminerals\tfrom\tfoods\tare\tmade\tavailable\tas\tmacronutrients\tand\tare\tdigested\tand\nabsorbed\tacross\tthe\tmucosal\tlayer,\tprimarily\tin\tthe\tsmall\tintestine\n\t(\nFig.\t1.9\n).\tBesides\tadequate\npassive\tand\ttransporter\tmechanisms,\tvarious\tfactors\taffect\tthe\tbioavailability\tof\tvitamins\tand | [
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] |
minerals,\tincluding\tthe\tpresence\tor\tabsence\tof\tother\tspecific\tnutrients,\tacid\tor\talkali,\tphytates,\tand\noxalates.\tThe\tliters\tof\tfluid\tthat\tare\tsecreted\teach\tday\tfrom\tthe\tGIT\tserve\tas\ta\tsolvent,\ta\tvehicle\tfor\nchemical\treactions,\tand\ta\tmedium\tfor\ttransfer\tof\tseveral\tnutrients.\nFIG.\t1.9\nSites\tof\tsecretion\tand\tabsorption\tin\tthe\tgastrointestinal\ttract. | [
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] |
Thus\tdrugs\tmay\tshare\tor\tcompete\twith\n\tmechanisms\tfor\tthe\tabsorption\tnutrients\tinto\tintestinal\tcells.\nMineral\tabsorption\tis\tmore\tcomplex,\tespecially\tthe\tabsorption\tof\tthe\tcation\tminerals.\tThese\ncations,\tsuch\tas\tselenium,\tare\tmade\tavailable\tfor\tabsorption\tby\tthe\tprocess\tof\t\nchelation\n,\tin\twhich\ta | [
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] |
chelation\n,\tin\twhich\ta\nmineral\tis\tbound\tto\ta\tligand—usually\tan\tacid,\tan\torganic\tacid,\tor\tan\tamino\tacid—so\tthat\tit\tis\tin\ta\nform\tabsorbable\tby\tintestinal\tcells\t(see\t\nChapter\t11\n).\nIron\tand\tzinc\tabsorption\tshare\tseveral\tcharacteristics\tin\tthat\tthe\tefficiency\tof\tabsorption\tpartly | [
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consumed.\n\tFermenting,\tsoaking,\tsprouting\tand\tpretreatment\twith\tphytase\tenzymes\timproves\tthe\nbioavailability\tof\tiron\tand\tzinc\tfrom\tplant\tbased\tfoods\tsuch\tas\tgrains,\tlegumes,\tnuts\tand\tseeds\n(\nGupta\tet\tal,\t2015\n).\tThe\tabsorption\tof\tzinc\tis\timpaired\twith\tdisproportionately\tincreased\tamounts\tof | [
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magnesium,\tcalcium,\tand\tiron.\tCalcium\tabsorption\tinto\tthe\tenterocyte\toccurs\tthrough\tchannels\tin\nthe\tbrush\tborder\tmembrane,\n\twhere\tit\tis\tbound\tto\ta\tspecific\tprotein\tcarrier\tfor\ttransportation\tacross\nthe\tbasolateral\tmembrane.\tThe\tprocess\tis\tregulated\tby\tthe\tpresence\tof\tvitamin\tD.\tPhosphorus\tis | [
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absorbed\tby\ta\tsodium\tphosphorus\tcotransporter,\twhich\talso\tis\tregulated\tby\tvitamin\tD\tor\tlow\nphosphate\tintake.\nThe\tGIT\tis\tthe\tsite\tof\timportant\tinteractions\tamong\tminerals.\tSupplementation\twith\tlarge\tamounts\nof\tiron\tor\tzinc\tmay\n\tdecrease\tthe\tabsorption\tof\tcopper.\tIn\tturn,\tthe\tpresence\tof\tcopper\tmay\tlower\tiron | [
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and\tmolybdenum\tabsorption.\tCobalt\tabsorption\tis\tincreased\tin\tpatients\twith\tiron\tdeficiency,\tbut\ncobalt\tand\tiron\tcompete\tand\tinhibit\tone\tanother’s\tabsorption.\tThese\tinteractions\tare\tprobably\tthe\nresult\tof\tan\toverlap\tof\tmineral\tabsorption\tmechanisms.\nMinerals\tare\ttransported\tin\tblood\tbound\tto\tprotein\tcarriers.\tThe\n\tprotein\tbinding\tis\teither\tspecific | [
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2\nIntake:\tEnergy\nCarol\tS.\tIreton-Jones,\tPhD,\tRDN,\tLD,\tCNSC,\tFASPEN,\tFAND\nKEY\tTERMS\nactivity\tthermogenesis\t(AT)\nbasal\tenergy\texpenditure\t(BEE)\nbasal\tmetabolic\trate\t(BMR)\ncalorie\ndirect\tcalorimetry\nestimated\tenergy\trequirement\t(EER)\nexcess\tpost-exercise\toxygen\tconsumption\t(EPOC)\nfacultative\tthermogenesis\nfat-free\tmass\t(FFM) | [
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shift\tthe\tfuel\tmixture\tof\tcarbohydrates,\tproteins,\tand\tfats\tto\taccommodate\tenergy\tneeds.\tHowever,\nconsuming\ttoo\tmuch\tor\ttoo\tlittle\tenergy\tover\ttime\tresults\tin\tbody\tweight\tchanges.\tThus\tbody\tweight\nreflects\tadequacy\tof\tenergy\tintake,\tbut\tit\tis\tnot\ta\treliable\tindicator\tof\tmacronutrient\tor\nmicronutrient\tadequacy. | [
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).\nComponents\tof\tenergy\texpenditure\nEnergy\tis\texpended\n\tby\tthe\thuman\tbody\tin\tthe\tform\tof\t\nbasal\tenergy\texpenditure\t(BEE)\n,\tthermic\neffect\tof\tfood\t(TEF),\tand\tactivity\tthermogenesis\t(AT).\tThese\tthree\tcomponents\tmake\tup\ta\tperson’s\ndaily\t\ntotal\tenergy\texpenditure\t(TEE)\n.\nBasal\tand\tresting\tenergy\texpenditure\nBEE,\tor\t\nbasal\tmetabolic\trate\t(BMR) | [
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constant\ton\ta\tdaily\tbasis.\nResting\tenergy\texpenditure\t(REE)\n,\tor\t\nresting\tmetabolic\trate\t(RMR)\n,\tis\tthe\tenergy\texpended\nin\tthe\tactivities\tnecessary\tto\tsustain\tnormal\tbody\tfunctions\tand\thomeostasis.\tThese\tactivities\tinclude\nrespiration\tand\tcirculation,\tthe\tsynthesis\tof\torganic\tcompounds,\tand\tthe\tpumping\tof\tions\tacross | [
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membranes.\tREE,\tor\tRMR,\tincludes\tthe\tenergy\trequired\tby\tthe\tcentral\tnervous\tsystem\n\tand\tfor\tthe\nmaintenance\tof\tbody\ttemperature.\tIt\tdoes\tnot\tinclude\tthermogenesis,\tactivity,\tor\tother\tenergy\nexpenditure\tand\tis\thigher\tthan\tthe\tBEE\tby\t10%\tto\t20%\t(\nIreton-Jones,\t2010\n).\tThe\tterms\t\nREE\n\tand\nRMR\n\tand\t\nBEE\n\tand\t\nBMR\n\tcan\tbe\tused\tinterchangeably,\tbut\t\nREE | [
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] |
and\nRMR\n\tand\t\nBEE\n\tand\t\nBMR\n\tcan\tbe\tused\tinterchangeably,\tbut\t\nREE\n\tand\t\nBEE\n\tare\tused\tin\tthis\tchapter.\nFactors\taffecting\tresting\tenergy\texpenditure\nNumerous\tfactors\tcause\tthe\tREE\tto\tvary\tamong\tindividuals,\n\tbut\tbody\tsize\tand\tcomposition\thave\tthe\ngreatest\teffect.\tSee\t\nChapter\t5\n\tfor\tdiscussion\tof\tmethods\tused\tto\tdetermine\tbody\tcomposition.\nAge. | [
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fat-free\tmass\t(FFM)\n\tper\tdecade\n(\nKeys\tet\tal,\t1973\n).\tFortunately,\texercise\tcan\thelp\tmaintain\ta\thigher\tLBM\tand\ta\thigher\tREE.\nDecreases\tin\tREE\twith\tincreasing\tage\tmay\tbe\tpartly\trelated\tto\tage-associated\tchanges\n\tin\tthe\nrelative\tsize\tof\tLBM\tcomponents\t(\nCooper\tet\tal,\t2013\n).\nBody\tcomposition. | [
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Cooper\tet\tal,\t2013\n).\nBody\tcomposition.\nFFM,\tor\tLBM,\tmakes\tup\tmost\tof\tthe\tmetabolically\tactive\ttissue\tin\tthe\tbody\tand\tis\tthe\tprimary\npredictor\tof\tREE.\tFFM\tcontributes\tto\tapproximately\t80%\tof\tthe\tvariations\tin\tREE\t(\nWang\tet\tal,\t2010\n).\nBecause\tof\ttheir\tgreater\tFFM,\tathletes\twith\tgreater\tmuscular\tdevelopment\thave\tan\tapproximately | [
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5%\thigher\tREE\tthan\tnonathletic\n\tindividuals.\tOrgans\tin\tthe\tbody\tcontribute\tto\theat\tproduction\t(\nFig.\n2.1\n).\tApproximately\t60%\tof\tREE\tcan\tbe\taccounted\tfor\tby\tthe\theat\tproduced\tby\t\nhigh-metabolic-rate\norgans\t(HMROs)\n:\tthe\tliver,\tbrain,\theart,\tspleen,\tintestines,\tand\tkidneys).\tIndeed,\tdifferences\tin | [
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FFM\tbetween\tethnic\tgroups\tmay\tbe\trelated\tto\tthe\ttotal\tmass\tof\tthese\tas\twell\tas\tmusculature\tand\npresence\tof\tobesity\t(\nWang\tet\tal,\t2012\n).\n\tRelatively\tsmall\tindividual\tvariation\tin\tthe\tmass\tof\tthe\tliver,\nbrain,\theart,\tspleen,\tand\tkidneys,\tcollectively\tor\tindividually,\tcan\tsignificantly\taffect\tREE\t(\nJaved\tet\tal,\n2010 | [
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Javed\tet\tal,\n2010\n).\tAs\ta\tresult,\testimating\tthe\tpercentage\tof\tenergy\texpenditure\tthat\tappendages\t(arms\tand\tlegs)\naccount\tfor\tin\toverall\tdaily\tenergy\texpenditure\tis\tdifficult,\talthough\tit\tis\tpresumably\ta\tsmall\tamount. | [
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FIG.\t2.1\nProportional\tcontribution\tof\torgans\tand\ttissues\tto\tcalculated\tresting\tenergy\nexpenditure.\n\tSource:\t\n(Modified\tand\tused\twith\tpermission\tfrom\tGallagher\tD\tet\tal:\tOrgan-tissue\tmass\tmeasurement\tallows\nmodeling\tof\tREE\tand\tmetabolically\tactive\ttissue\tmass,\t\nAm\tJ\tPhysiol\tEndocrinol\tMetab\n\t275:E249,\t1998.\tCopyright\tAmerican\nPhysiological\tSociety.) | [
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preciseness\tof\tan\tequation,\tbut\tmethodology\trelated\tto\nmeasurement\tof\tbody\tfat\tmay\tcause\tinaccuracies\tin\tbody\tfat\tand\tREE\t(\nWang\tet\tal,\t2012\n).\nClimate.\nThe\tREE\tis\taffected\tby\textremes\tin\tenvironmental\ttemperature.\tPeople\tliving\tin\ttropical\tclimates\nusually\thave\tREEs\tthat\tare\t5%\tto\t20%\thigher\tthan\tthose\tliving\tin\ttemperate\tareas.\tExercise\tin | [
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] |
with\taging,\tthis\tdifference\tbecomes\tless\tpronounced\t(\nCooper\tet\tal,\t2013\n).\nHormonal\tstatus.\nHormones\taffect\tmetabolic\trate.\tEndocrine\tdisorders,\tsuch\tas\thyperthyroidism\tand\thypothyroidism,\nincrease\tor\tdecrease\tenergy\texpenditure,\trespectively\t(see\t\nChapter\t30\n).\tStimulation\n\tof\tthe | [
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] |
Chapter\t30\n).\tStimulation\n\tof\tthe\nsympathetic\tnervous\tsystem\tduring\tperiods\tof\temotional\texcitement\tor\tstress\tcauses\tthe\trelease\tof\nepinephrine,\twhich\tpromotes\tglycogenolysis\tand\tincreased\tcellular\tactivity.\tGhrelin\tand\tpeptide\tYY\nare\tgut\thormones\tinvolved\tin\tappetite\tregulation\tand\tenergy\thomeostasis\t(\nLarson-Meyer\tet\tal,\n2010 | [
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Larson-Meyer\tet\tal,\n2010\n).\tThe\tmetabolic\trate\tof\twomen\tfluctuates\twith\tthe\tmenstrual\tcycle.\tDuring\tthe\tluteal\tphase\n(i.e.,\n\tthe\ttime\tbetween\tovulation\tand\tthe\tonset\tof\tmenstruation),\tmetabolic\trate\tincreases\tslightly\n(\nFerraro\tet\tal,\t1992\n).\tDuring\tpregnancy,\tgrowth\tin\tuterine,\tplacental,\tand\tfetal\ttissues,\talong\twith | [
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] |
the\tmother’s\tincreased\tcardiac\tworkload,\tcontributes\tto\tgradual\tincreases\tin\tBEE\tof\taround\t15%\n(\nChapter\t14\n).\nTemperature.\nFevers\tincrease\tREE\tby\tapproximately\t7%\tfor\teach\tdegree\tof\tincrease\tin\tbody\n\ttemperature\tabove\n98.6°F\tor\t13%\tfor\teach\tdegree\tmore\tthan\t37°C,\tas\tnoted\tby\tclassic\tstudies\t(\nHardy\tand\tDuBois,\n1937\n).\nOther\tfactors. | [
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] |
Hardy\tand\tDuBois,\n1937\n).\nOther\tfactors.\nCaffeine,\tnicotine,\tand\talcohol\t\nstimulate\tmetabolic\trate.\tCaffeine\tintakes\tof\t200\tto\t350\tmg\tin\tmen\t\nor\n240\tmg\tin\twomen\tmay\tincrease\tmean\tREE\tby\t7%\tto\t11%\tand\t8%\tto\t15%,\trespectively\t(\nCompher\tet\nal,\t2006\n).\tNicotine\tuse\tincreases\tREE\tby\tapproximately\t3%\tto\n\t4%\tin\tmen\tand\tby\t6%\tin\twomen; | [
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Energy\texpenditure\tmay\tbe\thigher\tin\tpeople\twho\tare\tobese\t(\nWang\tet\tal,\t2012\n).\tEnergy\texpenditure\nmay\tbe\tdepressed\tduring\tstarvation\tand\tchronic\tdieting\t(\nVolp\tet\tal,\t2011\n).\tA\tcase\n\tstudy\ndemonstrated\tdecreased\tenergy\texpenditure\tin\tpeople\twith\tbulimia\tthat\twas\timproved\twhen\tintake\nincreased\tconsistently\t(\nSedlet\tand\tIreton-Jones,\t1989\n). | [
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increased\tconsistently\t(\nSedlet\tand\tIreton-Jones,\t1989\n).\nThermic\teffect\tof\tfood\nThe\t\nthermic\teffect\tof\tfood\t(TEF)\n\tis\tthe\tincrease\tin\tenergy\texpenditure\tassociated\twith\tthe\nconsumption,\tdigestion,\tand\tabsorption\tof\tfood.\tThe\tTEF\taccounts\tfor\tapproximately\t10%\tof\tTEE\n(\nIreton-Jones,\t2010\n).\tThe | [
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(\nIreton-Jones,\t2010\n).\tThe\n\tTEF\tmay\talso\tbe\tcalled\tdiet-induced\tthermogenesis,\tspecific\tdynamic\naction,\tor\tthe\tspecific\teffect\tof\tfood.\tTEF\tcan\tbe\tseparated\tinto\tobligatory\tand\tfacultative\t(or\nadaptive)\tsubcomponents.\t\nObligatory\tthermogenesis\n\tis\tthe\tenergy\trequired\tto\tdigest,\tabsorb,\tand | [
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stimulated\tby\tsympathetic\tnervous\tactivity.\nThe\tTEF\tvaries\twith\tthe\tcomposition\tof\tthe\tdiet,\twith\tenergy\texpenditure\tincreasing\tdirectly\tafter\nfood\tintake,\tparticularly\tafter\tconsumption\tof\ta\tmeal\thigher\tin\tprotein\tcompared\twith\ta\tmeal\thigher\nin\tfat\n\t(\nTentolouris\tet\tal,\t2008\n).\tFat\tis\tmetabolized\tefficiently,\twith\tonly\t4%\twaste,\tcompared\twith\t25% | [
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expenditure\tand\tfat\toxidation\tand\tsuppress\thunger\t(\nHursel\tand\tWesterterp-Plantenga,\t2010\n;\nReinbach\tet\tal,\t2009\n).\tThe\trole\n\tof\tTEF\tin\tweight\tmanagement\tis\tdiscussed\tin\t\nChapter\t20\n.\nEnteral\tnutrition\t(tube\tfeeding)\tas\twell\tas\tparenteral\tnutrition\texert\ta\tthermic\teffect\ton\tenergy | [
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receiving\tenteral\tor\tparenteral\tnutrition\t(see\t\nChapter\t12\n).\nActivity\n\tthermogenesis\nBeyond\tREE\tand\tTEF,\tenergy\tis\texpended\tin\tphysical\tactivity,\teither\texercise-related\tor\tas\tpart\tof\ndaily\twork\tand\tmovement.\tThis\tis\treferred\tto\tas\t\nactivity\tthermogenesis\n.\tActivity\tthermogenesis | [
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activity\tthermogenesis\n.\tActivity\tthermogenesis\n(AT)\tincludes\tnonexercise\tactivity\tthermogenesis\t(NEAT),\tthe\tenergy\texpended\tduring\tactivities\tof\ndaily\tliving,\tand\tthe\tenergy\texpended\tduring\tsports\tor\tfitness\texercise.\nThe\tcontribution\n\tof\tphysical\tactivity\tis\tthe\tmost\tvariable\tcomponent\tof\tTEE,\twhich\tmay\tbe\tas\tlow | [
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as\t100\tkcal/day\tin\tsedentary\tpeople\tor\tas\thigh\tas\t3000\tkcal/day\tin\tathletes.\t\nNEAT\n\trepresents\tthe\nenergy\texpended\tduring\tthe\tworkday\tand\tduring\tleisure-type\tactivities\t(e.g.,\tshopping,\tfidgeting,\neven\tgum\tchewing),\twhich\tmay\taccount\tfor\tvast\tdifferences\tin\tenergy\tcosts\tamong\tpeople\t(see\nAppendix\t10\n).\tTEE\treflects\tREE, | [
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] |
Appendix\t10\n).\tTEE\treflects\tREE,\n\tTEF,\tand\tenergy\texpended\tfor\texercise,\tas\tdepicted\tin\t\nFig.\t2.2\n. | [
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FIG.\t2.2\nThe\tcomponents\tof\ttotal\tenergy\texpenditure:\tactivity,\tthermic\teffect\tof\tfood\t(TEF),\tand\tbasal\tor\nresting\tmetabolic\trate.\nIndividual\tAT\tvaries\tconsiderably,\tdepending\ton\tbody\tsize\tand\tthe\tefficiency\tof\tindividual\thabits\tof\nmotion.\tThe\tlevel\tof\tfitness\talso\taffects\tthe\tenergy\texpenditure\tof\tvoluntary\tactivity\tbecause\tof | [
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related\tto\tchildren,\tadolescents,\tor\tadults\t(\nMindell\tet\tal,\t2014\n).\tHowever,\tthis\tremains\tan\timportant\ncomponent\tof\tthe\toverall\tenergy\tintake\trecommendation\tsuggesting\n\tthat\tlow-cost\tquantitative\nassessment\tmethods\tare\tneeded\t(e.g.,\theart\trate\tmonitoring)\talong\twith\tthe\ttypical\tquestionnaire\nand\testimate. | [
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and\testimate.\nAdditional\tconsiderations\tin\tenergy\texpenditure\nExcess\tpost-exercise\toxygen\tconsumption\t(EPOC)\n\tis\tinfluenced\tby\tthe\tduration\tand\tmagnitude\nof\tphysical\tactivity.\tIn\ta\tstudy\tof\thigh-intensity\tintermittent\texercise,\tthere\twas\tan\tincrease\tin\tenergy\nexpenditure | [
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unilateral\tamputees,\tand\tno\tdifferences\tin\tenergy\texpenditure\twere\tfound\tbetween\tlevels\tof\namputation\tor\tspeed\twhen\twalking\t(\nGöktepe\tet\tal,\t2010\n).\nMeasurement\tof\tenergy\texpenditure\nThe\n\tstandard\tunit\tfor\tmeasuring\tenergy\tis\tthe\t\ncalorie\n,\twhich\tis\tthe\tamount\tof\theat\tenergy\trequired | [
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kilocalorie\n\t(kcal),\t1000\tcalories,\tis\tused\tto\tmeasure\tit.\tA\npopular\tconvention\tis\tto\tdesignate\tkilocalorie\tby\tCalorie\t(with\ta\tcapital\tC).\tIn\tthis\ttext,\thowever,\nkilocalorie\tis\tabbreviated\tkcal.\tThe\t\njoule\n\t(J)\tmeasures\tenergy\tin\tterms\tof\tmechanical\twork\tand\tis\tthe | [
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and\tresearch\tsettings.\nDirect\tcalorimetry\nDirect\tcalorimetry\n\tis\tpossible\tonly\twith\tspecialized\tand\texpensive\tequipment.\tAn\tindividual\tis\nmonitored\tin\ta\troom-type\tstructure\t(a\twhole-room\tcalorimeter)\tthat\tpermits\ta\tmoderate\tamount\tof\nactivity.\tIt\tincludes\tequipment\tthat\tmonitors\n\tthe\tamount\tof\theat\tproduced\tby\tthe\tindividual\tinside | [
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the\tamount\tof\theat\tproduced\tby\tthe\tindividual\tinside\nthe\tchamber\tor\troom.\tDirect\tcalorimetry\tprovides\ta\tmeasure\tof\tenergy\texpended\tin\tthe\tform\tof\theat\nbut\tprovides\tno\tinformation\ton\tthe\tkind\tof\tfuel\tbeing\toxidized.\tThe\tmethod\talso\tis\tlimited\tby\tthe\nconfined\tnature\tof\tthe\ttesting\tconditions.\tTherefore\tthe\tmeasurement\tof\tTEE\tusing\tthis\tmethod\tis | [
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not\trepresentative\tof\ta\tfree-living\t(i.e.,\tengaged\tin\n\tnormal\tdaily\tactivities)\tindividual\tin\ta\tnormal\nenvironment,\tbecause\tphysical\tactivity\twithin\tthe\tchamber\tis\tlimited.\tHigh\tcost,\tcomplex\nengineering,\tand\tscarcity\tof\tappropriate\tfacilities\taround\tthe\tworld\talso\tlimit\tthe\tuse\tof\tthis\tmethod. | [
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Indirect\tcalorimetry\nIndirect\tcalorimetry\t(IC)\n\tis\ta\tmore\tcommonly\tused\tmethod\tfor\tmeasuring\tenergy\texpenditure.\tAn\nindividual’s\toxygen\tconsumption\tand\n\tcarbon\tdioxide\tproduction\tare\tquantified\tover\ta\tgiven\tperiod.\nThe\tWeir\tequation\t(1949)\tand\ta\tconstant\trespiratory\tquotient\tvalue\tof\t0.85\tare\tused\tto\tconvert | [
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] |
oxygen\tconsumption\tto\tREE.\tThe\tequipment\tvaries\tbut\tusually\tinvolves\tan\tindividual\tbreathing\tinto\na\tmouthpiece\t(with\tnose\tclips),\ta\tmask\tthat\tcovers\tthe\tnose\tand\tmouth,\tor\ta\tventilated\thood\tthat\ncaptures\tall\texpired\tcarbon\tdioxide\t(\nFig.\t2.3\n).\tVentilated\thoods\tare\tuseful\tfor\tshort-\tand\tlong-term\nmeasurements.\nFIG.\t2.3\nA, | [
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] |
measurements.\nFIG.\t2.3\nA,\n\tMeasuring\tresting\tenergy\texpenditure\tusing\ta\tventilated\thood\tsystem.\t(Courtesy\tMRC\nMitochondrial\tBiology\tUnit,\tCambridge,\tEngland.).\t\nB,\n\tMeasuring\tresting\tenergy\texpenditure\tusing\ta\thandheld\nsystem.\n\tSource:\t\n(Courtesy\tKorr.)\nIC\tmeasurements\tare\tachieved\tusing\tequipment\tcalled\ta\t\nmetabolic\tmeasurement\tcart\n\tor\tan | [
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production.\n\tThese\thave\teasy\tmobility\tand\tare\trelatively\tlow\tcost\t(\nHipskind\tet\tal,\t2011\n).\nA\tstrict\tprotocol\tshould\tbe\tfollowed\t\nbefore\tperforming\tIC\tmeasurement.\tFor\thealthy\tpeople,\ta\nminimum\tof\t\na\t4-hour\tfast\tafter\tmeals\tand\tsnacks\tis\trecommended.\tCaffeine\t\nshould\tbe\tavoided\tfor\tat\nleast\t4\thours,\tand\talcohol\tand\tsmoking | [
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should\tbe\tavoided\tfor\tat\nleast\t4\thours,\tand\talcohol\tand\tsmoking\t\nfor\tat\tleast\t2\thours.\tTesting\tshould\toccur\tno\tsooner\tthan\t2\nhours\t\nafter\tmoderate\n\texercise;\tafter\tvigorous\tresistance\texercise,\ta\t\n14-hour\tperiod\tis\tadvised\n(\nCompher\tet\tal,\t2006\n).\tTo\tachieve\ta\t\nsteady-state\tmeasurement,\tthere\tshould\tbe\ta\trest\tperiod\tof\t10\tto | [
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