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Clinical Trials RegistrationNCT00138476 .
CONCLUSIONS
We compared the disease entities , complication incidence , and average symptom duration between the groups .
METHODS
Modest weight loss achieved via a relatively brief , non-intensive intervention using a commercial format can yield significant improvements in cardiovascular disease risk factors , particularly among individuals with initially higher-risk values .
CONCLUSIONS
Incremental costs of prophylaxis suggested a small cost saving but were not statistically significant , comparing the two groups .
RESULTS
The objective of this research project is to understand and to improve workers ' recovery from work stress .
BACKGROUND
A multicenter randomized waitlist-controlled trial was conducted .
METHODS
Adoption of short message services ( SMS ) reminders has been shown to enhance attendance in some medical settings .
BACKGROUND
Competencias para adolescentes con una sexualidad saludable ( COMPAS ) is a school-based HIV prevention program that has been shown to be effective in reducing sexual risk behaviors among adolescents in Spain .
OBJECTIVE
Patients with complex PTSD seem to react favourably to emotion regulation therapy .
CONCLUSIONS
Coronary sinus ET-1 level after CPB ( CS-T2 ) in CABG group correlated positively with troponin-I level 24 h postoperatively ( r ( 2 ) = 0.802 , p = 0.02 ) CONCLUSION : Off-pump myocardial revascularization attenuates ET-1 expression in all investigated vascular compartments .
RESULTS
The aim of this randomized , controlled pilot trial was to investigate the feasibility of muscle-training exercises in patients with spinal bone metastases under radiotherapy .
BACKGROUND
Based on the findings of 3D reconstruction of peripancreatic vessels , the appropriate method for individualized tumor resection was determined .
METHODS
Therefore , SLNE with the use of radiocolloid , followed if possible by single-photon emission computed tomography , remains the gold standard .
CONCLUSIONS
The treatment was given three times a week for both groups and ten times made an observation course .
METHODS
A recent study showed that aggressive lipid-lowering therapy with strong statins could achieve coronary artery plaque regression , as evaluated with gray-scale intravascular ultrasound ( IVUS ) .
OBJECTIVE
Of 636 VLBW infants in cohort 1 ) , 569 ( 89 % ) received empiric antibiotics for suspected early-onset sepsis .
RESULTS
We also compared clinical and procedural characteristics of trial subjects undergoing percutaneous coronary intervention ( PCI ) with drug-eluting stents to contemporaneous patients within the National Cardiovascular Data Registry CathPCI Registry .
RESULTS
Both groups showed favorable cardiopulmonary safety profiles .
RESULTS
Other measures of symptoms of psychopathology , and neuroendocrine and psychophysiological disorders are secondary outcome measures .
METHODS
Conservative orthotic treatments rely on different mechanisms , such as three-point bending systems or hinges forcing external rotation of the leg and knee stabilization , to alter the biomechanics of the lower limbs and thus reduce knee loading on the affected compartment in patients with knee osteoarthritis ( KOA ) .
BACKGROUND
Proactive , IVR-facilitated outreach enables engagement with low-SES smokers .
CONCLUSIONS
UK Medical Research Council , Health Foundation UK , Stroke Association UK , Chest Heart Stroke Scotland , Scottish Funding Council SINAPSE Collaboration , and multiple governmental and philanthropic national funders .
BACKGROUND
Thus , a rational choice of one of these techniques may be better for the perioperative safety of thyroid tumor patients with a difficult airway .
CONCLUSIONS
Obstruction occurred more often ( 8.2 % vs 1.1 % ; P < .0001 ) .
RESULTS
Such sealant did not increase the rates of lymphedema .
CONCLUSIONS
A total of 1,400 consecutive patients undergoing diagnostic coronary angiography were recruited and randomized to the RRA ( number [ n ] = 700 ) or LRA ( n = 700 ) group .
METHODS
The aim of this multicenter , prospective , randomized , crossover trial is to compare , in critical care patients receiving insulin infusion therapy ( IIT ) , the pharmacodynamic of Humulin insulin ( Hlin ) , currently used as `` standard of care , '' and Humalog insulin ( Hlog ) , a shorter acting insulin formulation .
BACKGROUND
There was a statistically significant reduction in pain at all illumination points during the illumination phase but no significant difference in discomfort levels in the first 72 h post illumination .
RESULTS
Besides , it was also evaluated the prepare efficacy related to the presence of fecal residue .
METHODS
Patients with improved American College of Rheumatology ( ACR ) and 28-joint Disease Activity Score ( DAS28 ) C-reactive protein ( CRP ) responses at Week 16 sustained their responses through Week 52 .
RESULTS
A randomized , double-blind , placebo-controlled trial , with 12-week treatment and 4-week follow-up , was conducted with 204 treatment-seeking participants having MA dependence per DSM-IV , who used MA on a less-than-daily basis .
METHODS
Transfused blood may have immunomodulatory and proinflammatory effects .
BACKGROUND
SSO application may retard postnatal skin barrier maturation in preterm infants .
CONCLUSIONS
Adverse events were reported with similar frequency in the BI 655066 and placebo groups .
RESULTS
55 cases in each one .
METHODS
We undertook an open-label randomised controlled trial alongside two observational cohorts in eastern Uganda , an area with high HIV prevalence , malaria transmission intensity , and antifolate resistance .
METHODS
Initiation of TXA treatment within 3 hours of injury reduced the hazard of death due to bleeding on the day of the injury by 28 % ( HR = 0.72 , 0.60 to 0.86 ) .
RESULTS
Treatment failure : if any of the following conditions apply : ( 1 ) lack of clinical improvement at 72h or more after starting therapy ; ( 2 ) persistent bacteraemia ( positive blood cultures on day 7 ) ; ( 3 ) therapy is discontinued early due to adverse effects or for some other reason based on clinical judgement ; ( 4 ) relapse of MRSA bacteraemia before the TOC visit ; ( 5 ) death for any reason before the TOC visit .
METHODS
Social workers are adept at gathering information but struggle with analysis and assessment of risk .
BACKGROUND
Secondary outcomes included changes in sexual activity , sexual distress , Derogatis Interview for Sexual Functioning , lean body mass , fat mass , muscle strength and power , and physical function .
METHODS
The intraoperative and postoperative complications were compared among three maintenance intracuff pressures .
METHODS
Parenting programmes , based on social learning theory , enhance a range of parenting behaviours , yet there is limited evidence for their effect on parental language .
BACKGROUND
In the BENEFIT trial , all subjects reported clinically meaningful improvements compared with baseline and returned to general population scores , both for physical composite score ( PCS ) and mental composite score Short Form ( 36 ) Health Survey at 12 to 36 months after transplantation .
RESULTS
Serum bilirubin levels were measured at 0 , 24th , 48th , 72nd , and 96th hour of phototherapy .
METHODS
The pain scores were significantly lower ( P < .05 ) in the noise-cancellation group compared with the jazz group at 10 min into the recovery period .
RESULTS
Only the results of the ACTH stimulation test but not baseline cortisol level was associated with poor prognosis .
CONCLUSIONS
Total exercise time and the time at which AT was achieved were also recorded .
METHODS
A goal for the training was determined according to the `` experienced '' doctors ' mean T1 .
METHODS
Of 80 standard grafts , 24 were eventually abandoned vs 17 heparin-bonded grafts ( P = .188 ) .
RESULTS
We will conduct a pilot randomised controlled trial with an embedded process study .
METHODS
However , no study investigated to what extent language impairment could affect patients ' behavioral responses .
BACKGROUND
Samples of breast milk were collected and analyzed using an ion-specific electrode .
METHODS
Imaging scans will address parameters of cerebral perfusion , vessel size imaging , and microvessel density ( the Q factor ) to estimate the degree of neovascularization in the brain .
METHODS
Leisure PA levels were assessed using the Modifiable Activity Questionnaire .
METHODS
Sixty subjects were randomized into an acupuncture group and a sham acupuncture group , 30 cases in each one .
METHODS
Our analysis showed a statistically significantly lower mean pharmaceutical expenditure of $ 989 ( 95 % CI , $ 648 - $ 1331 ) per patient per year in the polypill arm compared with usual care ( P < 0.001 ; adjusted , excluding polypill cost ) .
RESULTS
For instance , a child at the highest level of CFI , on average , consumed 494 kJ/d ( 118 kcal ) , 8 g/d of sugar , and 4 g/d of fat more than a food-secure child .
RESULTS
Mean treatment effect compared with the MARINA control group was similar for the MARINA treated group ( +17.6 letters ) and the FRB-MARINA cohort ( +15.9 letters ) .
RESULTS
HbA1c , diabetes-specific QoL ( ADDQoL ) and health status were measured in 510 screen-detected diabetes patients from the ADDITION-Cambridge trial at 1 and 5 years post diagnosis .
METHODS
This study is registered at the Netherlands Trial Register ( NTR3205 ) and ClinicalTrials.gov ( NCT01562431 ) .
BACKGROUND
Mean weight reduction with IDegLira was 2.7 kg vs. no weight change with IDeg , P < 0.0001 .
RESULTS
Administration of high doses of lycopene , GTCs , and selenium in men harboring HGPIN and/or ASAP was associated with a higher incidence of PCa at re-biopsy and expression of microRNAs implicated in PCa progression at molecular analysis .
CONCLUSIONS
Ten healthy female subjects with moderate to severe melasma were enrolled .
METHODS
15 southern Thailand schools and 3,706 pre-school children were recruited : 8 schools with 1,766 children as controls ; 7 schools with 1,940 children in the intervention groups .
METHODS
Linear programming was used to determine possible combinations of ingredients and micronutrient premix .
METHODS
N. sativa is thought to have multiple mechanisms of action and is cost-effective .
CONCLUSIONS
How to Use Drug Eluting Stents [ DES ] in Bifurcation Lesions ?
CONCLUSIONS
Inclusion criteria are adults 18-64 years old with non-specific low back pain lasting 12 weeks and a self-reported average pain intensity of 4 on a 0-10 scale .
METHODS
Consumption of black tea ( odds ratio [ OR ] 1.88 , 95 % confidence interval [ 95 % CI ] 1.03-3 .41 ) and coffee ( OR 1.57 , 95 % CI 0.95-2 .61 ) , but not green tea , was associated with an increased risk of SLE , while alcohol use ( OR 0.33 , 95 % CI 0.20-0 .55 ) was associated with a decreased risk of SLE .
RESULTS
Patients in the add-on group were prescribed 100 mg LAM and 10 mg ADV per day , while the monotherapy group received 0.5 mg ETV per day for 48 weeks .
METHODS
Mobile-phone-based text ( SMS ) messaging is an effective method for delivering smoking cessation assistance ; however , little is known about optimal program use .
BACKGROUND
Parental regulation did not mediate change in the screen behaviours .
RESULTS
Further analyses of the skin cancer cohort were undertaken to determine risk factors related to subsequent cancers .
METHODS
Bioavalability of SC palonosetron was 118 % ( 95 % IC : 69-168 ) .
RESULTS
To determine whether the addition of 26weeks of subcutaneous peginterferon -- 2b could reduce the requirement for systemic corticosteroids and conventional immunosuppressive medication in patients with Behet 's disease ( BD ) .
OBJECTIVE
The comparison of the outcomes , based on percentage change from baseline , showed no significant differences between the emollient and HC arm at any time point .
RESULTS
We found significant reductions in severity scores for sneezing , runny nose , stuffy nose and symptoms from eyes and lower airways , both separately and together ( all p < 0.001 ) .
RESULTS
The rohe ( tribal area ) of Waikato-Tainui .
METHODS
NTC also resulted in comparable results for both the response rates of the other evaluation points and incidence of adverse events compared to those of onabotulinumtoxin A.
RESULTS
Septal stimulation showed decreased trend in interventricular dyssynchrony .
CONCLUSIONS
EUDRACT Number : 2012-002988-10 .
BACKGROUND
At 1 year , letrozole resulted in higher LH ( L 6.1 2.5 vs A 3.2 1.7 IU/L ) and testosterone ( 1038 348 vs 536 216 ng/dL ) with lower estradiol ( 2.8 2.8 vs 5.6 2.9 pg/mL ) and IGF-1 ( 237 51 vs 331 79 ng/mL ) .
RESULTS
No language , publication date , or publication status restrictions were imposed .
METHODS
The incremental prognostic value of admission measurements of biomarkers beyond clinical characteristics and extent of coronary artery disease ( CAD ) in patients treated with primary percutaneous coronary intervention ( PPCI ) for ST-elevation myocardial infarction ( STEMI ) is unclear .
BACKGROUND
Additionally , the subjectively perceived effect of the steel insole with respect to comfort , restricted mobility and pain was assessed in a randomized , blinded and controlled ancillary study , using a cross-over design .
METHODS
Parathyroid hormone ( PTH ) promotes calcium reabsorption in the cortical distal nephron ( CDN ) .
OBJECTIVE
Fourth - and 5th-grade students ( n = 2278 ) reported on their physical activity during recess , and a subset ( n = 1537 ) wore accelerometers during recess .
METHODS
Randomized controlled study of single sessions of four neuromodulatory pain treatments and a control procedure .
METHODS
The median TTPs of the participants with progressive disease ( PD ) after first-line chemotherapy were 1.33 and 1.67 months in the combined and single docetaxel arms , respectively ( P = 0.946 ) .
RESULTS
ISRCTN 43852269 .
BACKGROUND
Topiramate was safe and well-tolerated in this sample of crack-cocaine dependent patients , but efficacy was not supported probably due to low acceptance of the treatment .
CONCLUSIONS
Physical performance is associated with working memory in older people with cognitive impairment .
CONCLUSIONS
The protocol was approved by the institutional review board .
METHODS
Adverse effects are common , occur early on in treatment and are reported to be one of the main reasons for discontinuation of antidepressant treatment .
BACKGROUND
No difference in the severity of pain or in knee function was found between the two groups .
RESULTS
In a randomized multicentre double-blind study , patients undergoing elective surgery were randomly assigned to breathe 60 % inspired N2O ( N2O group ) or 40 % oxygen ( AIR group ) .
METHODS
Use of data storage facilities could hinder effective review of blood glucose data and some participants reported an adverse impact on glycaemic control .
RESULTS
There was no significant difference in Qs/Qt and PaO2 at all time points between two groups .
RESULTS
The effect of LMWF-5A on pain was even more pronounced in patients with severe knee OA ( Kellgren Lawrence Grade IV ) : the estimated difference from control was -0.42 ( p = 0.02 ) .
RESULTS
The changes in MRI grade and bone marrow edema size were also compared .
METHODS