pmid
int64 26.1M
38.1M
| pubdate
int64 2.02k
2.02k
| software
listlengths 0
25
|
|---|---|---|
31,345,631 | 2,019 | [] |
31,776,349 | 2,019 | [
{
"contexts": [
"Furthermore, considering the combined effects of fat amount and distribution, a normal BMI accompanied by high AG ratio and/or high VAT mass but low %BF presents a much higher risk for metabolic syndrome than when %BF is high, most predominantly in women. "
],
"name": "THERM"
}
] |
31,777,708 | 2,019 | [] |
30,828,768 | 2,019 | [
{
"contexts": [
"Furthermore, this shift into the reperfusion era led to a downgraded recommendation for the use of β-blockers in post-MI patients (class IIa B recommendation) in the 2017 European Society of Cardiology (ESC) recommendations for the treatment of ST-segment elevation MI (STEMI). "
],
"name": "THERM"
}
] |
30,621,842 | 2,019 | [
{
"contexts": [
"She underwent drug-induced sleep endoscopy (DISE) with the concurrent application of PAP via two different mask types. "
],
"name": "DISE"
},
{
"contexts": [
"IMAGES: Drug-Induced Sleep Endoscopy: An Investigative Tool for Mechanisms of PAP Failure.This is a case report of a 60-year-old female with mild obstructive sleep apnea (OSA) who presented to CPAP Alternatives clinic following multiple failed attempts at positive airway pressure (PAP) therapy. ",
"She underwent drug-induced sleep endoscopy (DISE) with the concurrent application of PAP via two different mask types. ",
"She was recommended a trial of nasal autoPAP, which with the use of a chinstrap, resulted in both subjective and objective improvement of her OSA."
],
"name": "PAP"
},
{
"contexts": [
"IMAGES: Drug-Induced Sleep Endoscopy: An Investigative Tool for Mechanisms of PAP Failure.This is a case report of a 60-year-old female with mild obstructive sleep apnea (OSA) who presented to CPAP Alternatives clinic following multiple failed attempts at positive airway pressure (PAP) therapy. "
],
"name": "CPAP Alternatives clinic"
},
{
"contexts": [
"She was recommended a trial of nasal autoPAP, which with the use of a chinstrap, resulted in both subjective and objective improvement of her OSA."
],
"name": "autoPAP"
}
] |
30,583,233 | 2,019 | [] |
30,707,926 | 2,019 | [] |
30,687,961 | 2,019 | [] |
31,594,934 | 2,019 | [] |
30,696,838 | 2,019 | [] |
31,562,315 | 2,019 | [] |
31,164,752 | 2,019 | [
{
"contexts": [
"PEDIA: prioritization of exome data by image analysis.PURPOSE\n"
],
"name": "PEDIA"
},
{
"contexts": [
"PEDIA: prioritization of exome data by image analysis.PURPOSE\n"
],
"name": "PEDIA"
},
{
"contexts": [
"PEDIA: prioritization of exome data by image analysis.PURPOSE\n"
],
"name": "PEDIA"
}
] |
31,242,089 | 2,019 | [] |
31,460,703 | 2,019 | [] |
30,554,612 | 2,019 | [] |
29,700,752 | 2,019 | [] |
31,309,947 | 2,019 | [] |
30,741,665 | 2,019 | [] |
30,474,248 | 2,019 | [] |
30,716,673 | 2,019 | [] |
31,365,644 | 2,019 | [] |
30,067,388 | 2,019 | [] |
31,101,192 | 2,019 | [] |
31,504,008 | 2,019 | [] |
30,325,780 | 2,019 | [] |
29,506,420 | 2,019 | [] |
30,798,140 | 2,019 | [] |
30,381,000 | 2,019 | [] |
31,432,888 | 2,019 | [] |
31,150,784 | 2,019 | [] |
30,830,240 | 2,019 | [] |
31,513,168 | 2,019 | [] |
31,285,051 | 2,019 | [] |
31,133,654 | 2,019 | [] |
30,933,470 | 2,019 | [] |
31,727,171 | 2,019 | [
{
"contexts": [
"CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway.BACKGROUND\n",
"Further, a NSD1 knockout cell line was constructed by CRISPR/Cas9 genomic editing system, which was investigated in a battery of assays such as HCC cell proliferation, migration and invasion, followed by the investigation into NSD1 regulation on histone H3, Wnt10b and Wnt/β-catenin signaling pathway via ChIP. ",
"CRISPR/Cas9-mediated knockout of NSD1 promoted methylation of H3K27me3 and reduced methylation of H3K36me2, which inhibited Wnt10b expression. ",
"In conclusion, the study provides evidence that CRISPR/Cas9-mediated NSD1 knockout suppresses HCC cell proliferation and migration via the NSD1/H3/Wnt10b signaling pathway, suggesting that NSD1, H3 and Wnt10b may serve as potential targets for HCC."
],
"name": "CRISPR/Cas9"
},
{
"contexts": [
"Reverse transcription quantitative polymerase chain reaction (RT-qPCR) and Western blot analysis was performed to identify the expression of NSD1 in HCC cells and clinically obtained tissues. "
],
"name": "RT-qPCR"
},
{
"contexts": [
"Reverse transcription quantitative polymerase chain reaction (RT-qPCR) and Western blot analysis was performed to identify the expression of NSD1 in HCC cells and clinically obtained tissues. "
],
"name": "Western blot analysis"
},
{
"contexts": [
"The relationship between NSD1 expression and prognosis was analyzed by Kaplan-Meier survival curve. "
],
"name": "Kaplan-Meier survival curve"
},
{
"contexts": [
"Further, a NSD1 knockout cell line was constructed by CRISPR/Cas9 genomic editing system, which was investigated in a battery of assays such as HCC cell proliferation, migration and invasion, followed by the investigation into NSD1 regulation on histone H3, Wnt10b and Wnt/β-catenin signaling pathway via ChIP. "
],
"name": "ChIP"
}
] |
31,218,523 | 2,019 | [] |
31,023,982 | 2,019 | [] |
31,246,194 | 2,019 | [] |
31,181,725 | 2,019 | [] |
31,614,377 | 2,019 | [] |
31,618,683 | 2,019 | [] |
31,891,099 | 2,019 | [] |
31,249,577 | 2,019 | [
{
"contexts": [
"Metabolomic analysis showed a remarkable differences between pollinated and not-pollinated styles, where, except for glucose, all the other metabolites where less concentrated. ",
"Moreover, styles pollinated with compatible pollen showed the highest amount of sucrose than SI pollinated ones, which, in turn, contained highest amount of all the other metabolites, including aromatic compounds, such as flavonoids and a cynnamoil derivative."
],
"name": "THERM"
}
] |
31,694,245 | 2,019 | [] |
31,503,121 | 2,019 | [] |
30,588,639 | 2,019 | [] |
30,361,818 | 2,019 | [] |
31,659,991 | 2,019 | [] |
30,403,786 | 2,019 | [] |
31,652,697 | 2,019 | [
{
"contexts": [
"The preliminary test results will be successively extended by further experiments to contribute in the near future to develop innovative technologies, that can be implemented in the automotive industry for production of components with high strength, wear resistance, good thermal conductivity and low density, such as brake shoes, cylinder liners, piston rings and gears."
],
"name": "THERM"
},
{
"contexts": [
"The preliminary test results will be successively extended by further experiments to contribute in the near future to develop innovative technologies, that can be implemented in the automotive industry for production of components with high strength, wear resistance, good thermal conductivity and low density, such as brake shoes, cylinder liners, piston rings and gears."
],
"name": "THERM"
},
{
"contexts": [
"The preliminary test results will be successively extended by further experiments to contribute in the near future to develop innovative technologies, that can be implemented in the automotive industry for production of components with high strength, wear resistance, good thermal conductivity and low density, such as brake shoes, cylinder liners, piston rings and gears."
],
"name": "THERM"
},
{
"contexts": [
"The preliminary test results will be successively extended by further experiments to contribute in the near future to develop innovative technologies, that can be implemented in the automotive industry for production of components with high strength, wear resistance, good thermal conductivity and low density, such as brake shoes, cylinder liners, piston rings and gears."
],
"name": "THERM"
}
] |
30,632,114 | 2,019 | [] |
30,676,874 | 2,019 | [] |
30,935,538 | 2,019 | [] |
30,654,453 | 2,019 | [] |
30,185,832 | 2,019 | [] |
30,558,696 | 2,019 | [
{
"contexts": [
"A Perspective on Additional Approaches Beyond Organic Marker Compounds While Developing Analytical Monographs for Botanicals.Most of the Pharmacopoeia and other monographs that provide the quality specifications for botanicals typically contain identification and physicochemical tests, assays, and limits for contaminants. "
],
"name": "THERM"
}
] |
30,684,687 | 2,019 | [
{
"contexts": [
"These emerging potential contaminants have been identified in thermal paper products, according to recent studies, but their potential toxic effects and their migration into the environment remain unclear. "
],
"name": "THERM"
}
] |
30,666,453 | 2,019 | [] |
30,899,663 | 2,019 | [] |
30,361,789 | 2,019 | [] |
30,465,130 | 2,019 | [] |
31,720,276 | 2,019 | [] |
33,574,951 | 2,019 | [] |
30,454,953 | 2,019 | [
{
"contexts": [
"The vaccines comprised 14 manufacturers in 10 different countries including Nigeria were screened by Polymerase Chain Reaction. "
],
"name": "Polymerase Chain Reaction"
},
{
"contexts": [
"The vaccines comprised 14 manufacturers in 10 different countries including Nigeria were screened by Polymerase Chain Reaction. "
],
"name": "Polymerase Chain Reaction"
}
] |
31,048,870 | 2,019 | [] |
30,626,315 | 2,019 | [] |
30,066,057 | 2,019 | [
{
"contexts": [
"Furthermore, our study contributes to the lacunae of knowledge regarding environmental exposures and presses further investigation of outlying OC and OP exposure levels."
],
"name": "THERM"
}
] |
31,041,107 | 2,019 | [] |
31,354,752 | 2,019 | [] |
31,464,194 | 2,019 | [] |
31,405,115 | 2,019 | [] |
31,124,417 | 2,019 | [] |
31,199,303 | 2,019 | [] |
30,917,026 | 2,019 | [] |
30,561,547 | 2,019 | [] |
31,379,749 | 2,019 | [] |
31,132,748 | 2,019 | [] |
30,662,098 | 2,019 | [] |
31,287,375 | 2,019 | [] |
31,011,357 | 2,019 | [] |
30,244,375 | 2,019 | [] |
31,071,936 | 2,019 | [] |
31,715,824 | 2,019 | [] |
30,451,764 | 2,019 | [] |
30,707,581 | 2,019 | [
{
"contexts": [
"These magnetic exchange couplings affect the excited-state electronic structure in a manner that introduces variable degrees of spin forbiddenness into the nonradiative decay channel between the excited state and the electronic ground state."
],
"name": "ROUNDS"
}
] |
30,991,722 | 2,019 | [] |
30,605,662 | 2,019 | [] |
31,392,346 | 2,019 | [] |
31,519,136 | 2,019 | [] |
31,252,883 | 2,019 | [] |
31,048,102 | 2,019 | [] |
30,980,005 | 2,019 | [] |
31,409,020 | 2,019 | [] |
30,860,570 | 2,019 | [] |
31,369,631 | 2,019 | [] |
31,639,910 | 2,019 | [] |
31,525,228 | 2,019 | [
{
"contexts": [
"Development of a quantitative polymerase chain reaction assay and environmental DNA sampling methods for Giant Gartersnake (Thamnophis gigas).",
"The Giant Gartersnake (Thamnophis gigas) is a low density visually evasive species with a low detection probability based on standard field survey methods (e.g., traps, visual census). ",
"Habitat loss has resulted in extirpations or serious declines for T. gigas populations throughout the southern two thirds of its historic range. ",
"Uncertainty regarding its current distribution and occupancy present management challenges for the species. ",
"Enhancing survey sensitivity through development of environmental DNA sampling (eDNA) methods would improve compliance monitoring under the Endangered Species Act, recovery planning for T. gigas, and evaluation of California's Central Valley tule marsh habitat on which this species depends. ",
"To address these needs, we designed and validated diagnostic quantitative Polymerase Chain Reaction (qPCR) assays for identifying portions of the Cytochrome B (CytB) and the Nicotinamide adenine dinucleotide (NADH) dehydrogenase subunit 4 (ND4) genes of the T. gigas mitochondrial genome. ",
"The designed ND4 qPCR assay was not specific to T. gigas DNA and amplified DNA from a closely related and spatially co-occurring Thamnophis species (T.s. fitchi). ",
"The CytB T. gigas qPCR assay proved specific to a species level with a sensitivity that reliably detected T. gigas DNA at a concentration of 2.0x10-5 ng μL-1. ",
"To assess detection range, coordinated field sampling was conducted at aquatic sites with an observed and documented population of T. gigas. ",
"The T. gigas qPCR assay reliably detected DNA from samples taken 300m downstream from the known source. ",
"We then used environmental eDNA sampling and qPCR analysis to augment unsuccessful trap surveys in the southern range of T. gigas and detected DNA in 28 of the 52 locations sampled, confirming that T. gigas was still present at some sites where physical trapping failed to identify presence. ",
"QPCR-based DNA detection coupled with eDNA sampling methods provides an effective means to obtain critical population metrics from this otherwise cryptic, federally protected and hard to study organism, offering great promise for elucidating patterns of occupancy with greater efficiency and at far less cost than trapping methods, particularly where detection probabilities are low."
],
"name": "C"
},
{
"contexts": [
"To address these needs, we designed and validated diagnostic quantitative Polymerase Chain Reaction (qPCR) assays for identifying portions of the Cytochrome B (CytB) and the Nicotinamide adenine dinucleotide (NADH) dehydrogenase subunit 4 (ND4) genes of the T. gigas mitochondrial genome. ",
"The designed ND4 qPCR assay was not specific to T. gigas DNA and amplified DNA from a closely related and spatially co-occurring Thamnophis species (T.s. fitchi). ",
"The CytB T. gigas qPCR assay proved specific to a species level with a sensitivity that reliably detected T. gigas DNA at a concentration of 2.0x10-5 ng μL-1. ",
"The T. gigas qPCR assay reliably detected DNA from samples taken 300m downstream from the known source. ",
"We then used environmental eDNA sampling and qPCR analysis to augment unsuccessful trap surveys in the southern range of T. gigas and detected DNA in 28 of the 52 locations sampled, confirming that T. gigas was still present at some sites where physical trapping failed to identify presence. ",
"QPCR-based DNA detection coupled with eDNA sampling methods provides an effective means to obtain critical population metrics from this otherwise cryptic, federally protected and hard to study organism, offering great promise for elucidating patterns of occupancy with greater efficiency and at far less cost than trapping methods, particularly where detection probabilities are low."
],
"name": "qPCR"
},
{
"contexts": [
"QPCR-based DNA detection coupled with eDNA sampling methods provides an effective means to obtain critical population metrics from this otherwise cryptic, federally protected and hard to study organism, offering great promise for elucidating patterns of occupancy with greater efficiency and at far less cost than trapping methods, particularly where detection probabilities are low."
],
"name": "eDNA sampling methods"
}
] |
31,115,358 | 2,019 | [] |
31,876,710 | 2,019 | [] |