JerrySiRi/SWN_Bert_based_2019_2023_15000 · Datasets at Hugging Face

pmid int64 26.1M 38.1M	pubdate int64 2.02k 2.02k	software listlengths 0 25
30,897,957	2,019	[]
30,981,339	2,019	[ { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" } ]
30,126,688	2,019	[]
31,004,622	2,019	[]
31,590,102	2,019	[ { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" }, { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" }, { "contexts": [ "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. " ], "name": "traditional microscopes" }, { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" }, { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" } ]
31,149,608	2,019	[]
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31,526,605	2,019	[]
31,296,692	2,019	[]
30,445,399	2,019	[]
30,387,916	2,019	[ { "contexts": [ "A Pilot Study of Infrared Thermal Imaging to Detect Active Bone Lesions in Children With Chronic Nonbacterial Osteomyelitis.OBJECTIVE\n", "An inexpensive and rapid imaging tool, infrared thermal imaging, was evaluated for its utility to detect active bone lesions in extremities of children with CNO.\n\n\n", "All subjects underwent infrared thermal imaging of the lower extremities. ", "Infrared thermal data were analyzed using custom software by dividing the leg below the knee into 3 equal segments longitudinally and adding the distal femur segment as an equal length above the knee. ", "Larger studies are warranted to further evaluate the clinical utility of infrared thermal imaging for CNO detection." ], "name": "THERM" } ]
30,676,661	2,019	[ { "contexts": [ "Clozapine and risperidone were modeled together with their active metabolites, norclozapine and paliperidone, First, in PK-Sim a rat PBPK model was developed and optimized using literature plasma PK data. " ], "name": "PK-Sim" }, { "contexts": [ "Based on the simulated drug and metabolite concentrations in brainECF, drug-D2 receptor binding kinetics (association and dissociation rates) were incorporated in MoBi to predict RO. " ], "name": "MoBi" } ]
31,114,285	2,019	[]
31,115,530	2,019	[ { "contexts": [ "Furthermore, VSMCs in the medial layers of arteries from apolipoprotein E‑deficient mice and human atherosclerotic samples exhibited an increase in FGF signaling that was identified to be associated with an increase in the protein expression levels of pro‑inflammatory molecules, including C‑C motif chemokine ligand 2, C‑X‑C motif chemokine ligand (CXCL) 9, CXCL10 and CXCL11, compared with wild‑type mice and healthy control samples, respectively. " ], "name": "THERM" } ]
30,284,453	2,019	[]
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31,696,468	2,019	[ { "contexts": [ "MiR-15 suppressed the progression of bladder cancer by targeting BMI1 oncogene via PI3K/AKT signaling pathway.OBJECTIVE\n", "To investigate the role of microRNA-15 (miR-15) in the progression of bladder cancer (BC) cell and its underlying mechanism.\n\n\n", "Furthermore, the luciferase reporter assay was used to verify the target gene of miR-15. ", "Besides, Xenograft tumor formation assay was performed to confirm the effect of miR-15 on tumor growth.\n\n\n", "A low expression of miR-15 was detected by qRT-PCR, whereas the high expression of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1) was detected by immunocytochemical assay in BC tissues. ", "Moreover, miR-15 expression and BMI1 expression were significantly associated with the overall survival of BC patients. ", "MTT and transwell assay results stated that the up-regulation of miR-15 inhibited BC cell proliferation, migration, and invasion. ", "BMI-1 was verified as a direct target of miR-15 in BC using Luciferase reporter assay. ", "Besides, miR-15 regulated epithelial-mesenchymal transition (EMT)-related makers, protein kinase B (AKT), and the phosphorylation of AKT protein levels in BC using the Western blot assay. ", "Xenograft tumor formation assay indicated that the over-expression of miR-15 inhibited the tumor growth.\n\n\n", "We stated that miR-15 suppressed BC cell progression by targeting BMI1 through the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway, which provided a potential target for BC treatment." ], "name": "MiR-15" }, { "contexts": [ "MiR-15 suppressed the progression of bladder cancer by targeting BMI1 oncogene via PI3K/AKT signaling pathway.OBJECTIVE\n", "A low expression of miR-15 was detected by qRT-PCR, whereas the high expression of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1) was detected by immunocytochemical assay in BC tissues. ", "Moreover, miR-15 expression and BMI1 expression were significantly associated with the overall survival of BC patients. ", "We stated that miR-15 suppressed BC cell progression by targeting BMI1 through the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway, which provided a potential target for BC treatment." ], "name": "BMI1" }, { "contexts": [ "MiR-15 suppressed the progression of bladder cancer by targeting BMI1 oncogene via PI3K/AKT signaling pathway.OBJECTIVE\n" ], "name": "PI3K/AKT signaling pathway" }, { "contexts": [ "The abilities of cell proliferation and invasion were detected by Methyl thiazolyl tetrazolium (MTT) and transwell assay, respectively. " ], "name": "Methyl thiazolyl tetrazolium (MTT)" }, { "contexts": [ "The abilities of cell proliferation and invasion were detected by Methyl thiazolyl tetrazolium (MTT) and transwell assay, respectively. ", "MTT and transwell assay results stated that the up-regulation of miR-15 inhibited BC cell proliferation, migration, and invasion. " ], "name": "transwell assay" }, { "contexts": [ "Additionally, the relevant mRNA and protein expressions were measured by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR), Western blot and immunohistochemistry, respectively. ", "A low expression of miR-15 was detected by qRT-PCR, whereas the high expression of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1) was detected by immunocytochemical assay in BC tissues. " ], "name": "qRT-PCR" }, { "contexts": [ "Additionally, the relevant mRNA and protein expressions were measured by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR), Western blot and immunohistochemistry, respectively. ", "Besides, miR-15 regulated epithelial-mesenchymal transition (EMT)-related makers, protein kinase B (AKT), and the phosphorylation of AKT protein levels in BC using the Western blot assay. " ], "name": "Western blot" }, { "contexts": [ "Additionally, the relevant mRNA and protein expressions were measured by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR), Western blot and immunohistochemistry, respectively. " ], "name": "immunohistochemistry" }, { "contexts": [ "Furthermore, the luciferase reporter assay was used to verify the target gene of miR-15. ", "BMI-1 was verified as a direct target of miR-15 in BC using Luciferase reporter assay. " ], "name": "luciferase reporter assay" }, { "contexts": [ "Besides, Xenograft tumor formation assay was performed to confirm the effect of miR-15 on tumor growth.\n\n\n", "Xenograft tumor formation assay indicated that the over-expression of miR-15 inhibited the tumor growth.\n\n\n" ], "name": "Xenograft tumor formation assay" } ]
31,554,575	2,019	[]
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31,552,875	2,019	[ { "contexts": [ "Furthermore, we demonstrated that HCH directed microglia polarization towards anti-inflammatory M2 polarization. " ], "name": "THERM" } ]
31,683,589	2,019	[ { "contexts": [ "Reactivation of HBV infection is a life-threatening condition observed in patients with CHB receiving chemotherapy or other medications. ", "Furthermore, DNA damage leading to the activation of ATM and ATR transcription, results in the reactivation of HBV replication." ], "name": "THERM" } ]
31,820,523	2,019	[ { "contexts": [ "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "SHIPS" }, { "contexts": [ "Extending Surface-Enhanced Raman Spectroscopy to Liquids Using Shell-Isolated Plasmonic Superstructures.Invited for the cover of this issue is the group of Bert M. Weckhuysen at Utrecht University. ", "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "shell-isolated plasmonic superstructures" }, { "contexts": [ "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "SHINERS" }, { "contexts": [ "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "shell-isolated nanoparticle-enhanced Raman spectroscopy" } ]
31,283,187	2,019	[]
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30,890,181	2,019	[ { "contexts": [ "Here we employed the random forest algorithm to develop VirMiner, a web-based phage contig prediction tool especially sensitive for high-abundances phage contigs, trained and validated by paired metagenomic and phagenomic sequencing data from the human gut flora.\n\n\n", "VirMiner achieved 41.06% ± 17.51% sensitivity and 81.91% ± 4.04% specificity in the prediction of phage contigs. ", "In particular, for the high-abundance phage contigs, VirMiner outperformed other tools (VirFinder and VirSorter) with much higher sensitivity (65.23% ± 16.94%) than VirFinder (34.63% ± 17.96%) and VirSorter (18.75% ± 15.23%) at almost the same specificity. ", "Moreover, VirMiner provides the most comprehensive phage analysis pipeline which is comprised of metagenomic raw reads processing, functional annotation, phage contig identification, and phage-host relationship prediction (CRISPR-spacer recognition) and supports two-group comparison when the input (metagenomic sequence data) includes different conditions (e.g., case and control). ", "Application of VirMiner to an independent cohort of human gut metagenomes obtained from individuals treated with antibiotics revealed that 122 KEGG orthology and 118 Pfam groups had significantly differential abundance in the pre-treatment samples compared to samples at the end of antibiotic administration, including clustered regularly interspaced short palindromic repeats (CRISPR), multidrug resistance, and protein transport. ", "The VirMiner webserver is available at http://sbb.hku.hk/VirMiner/ .\n\n\n", "Compared to VirSorter and VirFinder-the most widely used tools-VirMiner is able to capture more high-abundance phage contigs which could play key roles in infecting bacteria and modulating microbial community dynamics.\n\n\n" ], "name": "VirMiner" }, { "contexts": [ "In particular, for the high-abundance phage contigs, VirMiner outperformed other tools (VirFinder and VirSorter) with much higher sensitivity (65.23% ± 16.94%) than VirFinder (34.63% ± 17.96%) and VirSorter (18.75% ± 15.23%) at almost the same specificity. ", "Compared to VirSorter and VirFinder-the most widely used tools-VirMiner is able to capture more high-abundance phage contigs which could play key roles in infecting bacteria and modulating microbial community dynamics.\n\n\n" ], "name": "VirFinder" }, { "contexts": [ "In particular, for the high-abundance phage contigs, VirMiner outperformed other tools (VirFinder and VirSorter) with much higher sensitivity (65.23% ± 16.94%) than VirFinder (34.63% ± 17.96%) and VirSorter (18.75% ± 15.23%) at almost the same specificity. ", "Compared to VirSorter and VirFinder-the most widely used tools-VirMiner is able to capture more high-abundance phage contigs which could play key roles in infecting bacteria and modulating microbial community dynamics.\n\n\n" ], "name": "VirSorter" } ]
31,803,068	2,019	[]
31,490,226	2,019	[]
31,292,922	2,019	[]
30,955,970	2,019	[]
33,266,948	2,019	[]
30,580,119	2,019	[ { "contexts": [ "Furthermore, it would be advisable to have redundancy in any conservation measures and wildfire-risk mitigations to ensure that losses due to wildfire on one area do not jeopardize all conservation projects within the landscape." ], "name": "THERM" } ]
30,833,913	2,019	[]
30,926,985	2,019	[]
30,658,313	2,019	[]
37,312,344	2,019	[]
29,101,736	2,019	[]
31,403,823	2,019	[]
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31,695,805	2,019	[]
31,407,115	2,019	[]
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30,823,651	2,019	[ { "contexts": [ "Comparative Analysis of Properties of PVA Composites with Various Nanofillers: Pristine Clay, Organoclay, and Functionalized Graphene.Poly(vinyl alcohol) (PVA) nanocomposites containing three different nanofillers are prepared and compared in terms of their thermal properties, morphologies, and oxygen permeabilities. ", "In the thermal properties, SPT and OMB are most effective when the filler corresponds to 5 wt% and 7 wt% for HDA-GS, respectively, and the gas barrier is most effective with respect to 5 wt% content in all fillers. ", "Among the three types of nanofillers that are investigated, OMB exhibits optimal results in terms of thermal stability and the gas barrier effect." ], "name": "THERM" } ]
30,827,614	2,019	[]
31,327,986	2,019	[]
31,367,745	2,019	[ { "contexts": [ "Using SOAPdenovo2 and 170 Gbp of Illumina paired-end and mate-pair reads, we generated a 2.6-Gbp male Masai giraffe genome assembly, with a scaffold N50 of 3 Mbp. " ], "name": "SOAPdenovo2" }, { "contexts": [ "Using SOAPdenovo2 and 170 Gbp of Illumina paired-end and mate-pair reads, we generated a 2.6-Gbp male Masai giraffe genome assembly, with a scaffold N50 of 3 Mbp. " ], "name": "Illumina paired-end and mate-pair reads" }, { "contexts": [ "The incorporation of 114.6 Gbp of Chicago library sequencing data resulted in a HiRise SOAPdenovo + Chicago assembly with an N50 of 48 Mbp and containing 95% of expected genes according to BUSCO analysis. " ], "name": "Chicago library sequencing data" }, { "contexts": [ "Using the Reference-Assisted Chromosome Assembly tool, we were able to order and orient scaffolds into 42 predicted chromosome fragments (PCFs). " ], "name": "Reference-Assisted Chromosome Assembly tool" }, { "contexts": [ "Using fluorescence in situ hybridization, we placed 153 cattle bacterial artificial chromosomes onto giraffe metaphase spreads to assess and assign the PCFs on 14 giraffe autosomes and the X chromosome resulting in the final assembly with an N50 of 177.94 Mbp. " ], "name": "fluorescence in situ hybridization" } ]
31,267,167	2,019	[ { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" }, { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" }, { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" }, { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" } ]
31,302,289	2,019	[]
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31,798,851	2,019	[]
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31,284,313	2,019	[ { "contexts": [ "Furthermore, various supplements have got potentially an influence on the characteristics of depression.\n\n\n" ], "name": "THERM" } ]
31,661,814	2,019	[]
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31,124,039	2,019	[ { "contexts": [ "Furthermore, subgroup analysis stratified by children/adolescent and adult groups showed same trend.\n\n\n" ], "name": "THERM" } ]
31,769,611	2,019	[ { "contexts": [ "Transmission electron microscopy, fluorescence, and Raman spectroscopy are used to evaluate the biodegradation of GQDs. " ], "name": "Transmission electron microscopy" }, { "contexts": [ "Transmission electron microscopy, fluorescence, and Raman spectroscopy are used to evaluate the biodegradation of GQDs. " ], "name": "fluorescence" }, { "contexts": [ "Transmission electron microscopy, fluorescence, and Raman spectroscopy are used to evaluate the biodegradation of GQDs. " ], "name": "Raman spectroscopy" }, { "contexts": [ "Molecular dynamics simulations show intimate interactions between the enzymes and the GQDs. " ], "name": "molecular dynamics simulations" } ]
30,543,015	2,019	[]

30,897,957

2,019

[]

30,981,339

2,019

[ { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" }, { "contexts": [ "US exhibited a high amylose content (35.3%), low stability against thermal degradation, and a B-type crystalline structure. ", "In addition, good mechanical properties, opacity and stability against thermal degradation were obtained. ", "Furthermore, the films appear as a potential material for food packaging." ], "name": "THERM" } ]

30,126,688

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31,004,622

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[]

31,590,102

2,019

[ { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" }, { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" }, { "contexts": [ "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. " ], "name": "traditional microscopes" }, { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" }, { "contexts": [ "Efficacy of USB microscopes for imaging forensic materials.USB microscopy, a relatively new and developing technology, offers a highly portable and relatively inexpensive means for performing microscopy. ", "However, it has not been established that USB microscopes are capable of imaging at a level deemed sufficient for forensic requirements. ", "The purpose of this study was to determine the value, applicability, and limitations of current USB microscope technology by comparing USB microscopes with traditional microscopes by collecting images of common forensic trace materials. ", "The USB microscopes were highly portable, easy to work with, and able to take an image in any orientation. ", "USB microscopes do not share the same level of resolution, image quality, or image contrast as the most sophisticated microscopes. ", "However, USB microscopes could add value to forensic investigations when used for preliminary exams, low magnification imaging of samples, and imaging scenarios that require magnification but don't conform to traditional microscopy." ], "name": "USB microscopes" } ]

31,149,608

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[]

30,358,176

2,019

[]

31,817,250

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[]

30,880,585

2,019

[]

30,311,550

2,019

[]

30,408,273

2,019

[]

31,436,379

2,019

[]

31,031,445

2,019

[]

31,161,387

2,019

[]

31,526,605

2,019

[]

31,296,692

2,019

[]

30,445,399

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30,387,916

2,019

[ { "contexts": [ "A Pilot Study of Infrared Thermal Imaging to Detect Active Bone Lesions in Children With Chronic Nonbacterial Osteomyelitis.OBJECTIVE\n", "An inexpensive and rapid imaging tool, infrared thermal imaging, was evaluated for its utility to detect active bone lesions in extremities of children with CNO.\n\n\n", "All subjects underwent infrared thermal imaging of the lower extremities. ", "Infrared thermal data were analyzed using custom software by dividing the leg below the knee into 3 equal segments longitudinally and adding the distal femur segment as an equal length above the knee. ", "Larger studies are warranted to further evaluate the clinical utility of infrared thermal imaging for CNO detection." ], "name": "THERM" } ]

30,676,661

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[ { "contexts": [ "Clozapine and risperidone were modeled together with their active metabolites, norclozapine and paliperidone, First, in PK-Sim a rat PBPK model was developed and optimized using literature plasma PK data. " ], "name": "PK-Sim" }, { "contexts": [ "Based on the simulated drug and metabolite concentrations in brainECF, drug-D2 receptor binding kinetics (association and dissociation rates) were incorporated in MoBi to predict RO. " ], "name": "MoBi" } ]

31,114,285

2,019

[]

31,115,530

2,019

[ { "contexts": [ "Furthermore, VSMCs in the medial layers of arteries from apolipoprotein E‑deficient mice and human atherosclerotic samples exhibited an increase in FGF signaling that was identified to be associated with an increase in the protein expression levels of pro‑inflammatory molecules, including C‑C motif chemokine ligand 2, C‑X‑C motif chemokine ligand (CXCL) 9, CXCL10 and CXCL11, compared with wild‑type mice and healthy control samples, respectively. " ], "name": "THERM" } ]

30,284,453

2,019

[]

30,593,825

2,019

[]

29,683,354

2,019

[]

31,540,101

2,019

[]

31,255,496

2,019

[]

31,309,785

2,019

[]

31,595,352

2,019

[]

30,901,869

2,019

[]

30,626,742

2,019

[]

31,696,468

2,019

[ { "contexts": [ "MiR-15 suppressed the progression of bladder cancer by targeting BMI1 oncogene via PI3K/AKT signaling pathway.OBJECTIVE\n", "To investigate the role of microRNA-15 (miR-15) in the progression of bladder cancer (BC) cell and its underlying mechanism.\n\n\n", "Furthermore, the luciferase reporter assay was used to verify the target gene of miR-15. ", "Besides, Xenograft tumor formation assay was performed to confirm the effect of miR-15 on tumor growth.\n\n\n", "A low expression of miR-15 was detected by qRT-PCR, whereas the high expression of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1) was detected by immunocytochemical assay in BC tissues. ", "Moreover, miR-15 expression and BMI1 expression were significantly associated with the overall survival of BC patients. ", "MTT and transwell assay results stated that the up-regulation of miR-15 inhibited BC cell proliferation, migration, and invasion. ", "BMI-1 was verified as a direct target of miR-15 in BC using Luciferase reporter assay. ", "Besides, miR-15 regulated epithelial-mesenchymal transition (EMT)-related makers, protein kinase B (AKT), and the phosphorylation of AKT protein levels in BC using the Western blot assay. ", "Xenograft tumor formation assay indicated that the over-expression of miR-15 inhibited the tumor growth.\n\n\n", "We stated that miR-15 suppressed BC cell progression by targeting BMI1 through the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway, which provided a potential target for BC treatment." ], "name": "MiR-15" }, { "contexts": [ "MiR-15 suppressed the progression of bladder cancer by targeting BMI1 oncogene via PI3K/AKT signaling pathway.OBJECTIVE\n", "A low expression of miR-15 was detected by qRT-PCR, whereas the high expression of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1) was detected by immunocytochemical assay in BC tissues. ", "Moreover, miR-15 expression and BMI1 expression were significantly associated with the overall survival of BC patients. ", "We stated that miR-15 suppressed BC cell progression by targeting BMI1 through the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway, which provided a potential target for BC treatment." ], "name": "BMI1" }, { "contexts": [ "MiR-15 suppressed the progression of bladder cancer by targeting BMI1 oncogene via PI3K/AKT signaling pathway.OBJECTIVE\n" ], "name": "PI3K/AKT signaling pathway" }, { "contexts": [ "The abilities of cell proliferation and invasion were detected by Methyl thiazolyl tetrazolium (MTT) and transwell assay, respectively. " ], "name": "Methyl thiazolyl tetrazolium (MTT)" }, { "contexts": [ "The abilities of cell proliferation and invasion were detected by Methyl thiazolyl tetrazolium (MTT) and transwell assay, respectively. ", "MTT and transwell assay results stated that the up-regulation of miR-15 inhibited BC cell proliferation, migration, and invasion. " ], "name": "transwell assay" }, { "contexts": [ "Additionally, the relevant mRNA and protein expressions were measured by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR), Western blot and immunohistochemistry, respectively. ", "A low expression of miR-15 was detected by qRT-PCR, whereas the high expression of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1) was detected by immunocytochemical assay in BC tissues. " ], "name": "qRT-PCR" }, { "contexts": [ "Additionally, the relevant mRNA and protein expressions were measured by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR), Western blot and immunohistochemistry, respectively. ", "Besides, miR-15 regulated epithelial-mesenchymal transition (EMT)-related makers, protein kinase B (AKT), and the phosphorylation of AKT protein levels in BC using the Western blot assay. " ], "name": "Western blot" }, { "contexts": [ "Additionally, the relevant mRNA and protein expressions were measured by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR), Western blot and immunohistochemistry, respectively. " ], "name": "immunohistochemistry" }, { "contexts": [ "Furthermore, the luciferase reporter assay was used to verify the target gene of miR-15. ", "BMI-1 was verified as a direct target of miR-15 in BC using Luciferase reporter assay. " ], "name": "luciferase reporter assay" }, { "contexts": [ "Besides, Xenograft tumor formation assay was performed to confirm the effect of miR-15 on tumor growth.\n\n\n", "Xenograft tumor formation assay indicated that the over-expression of miR-15 inhibited the tumor growth.\n\n\n" ], "name": "Xenograft tumor formation assay" } ]

31,554,575

2,019

[]

30,912,222

2,019

[]

30,659,505

2,019

[]

29,417,473

2,019

[]

30,653,521

2,019

[]

31,665,664

2,019

[]

31,010,717

2,019

[]

30,921,538

2,019

[]

30,621,090

2,019

[]

31,272,962

2,019

[]

31,603,389

2,019

[]

30,681,802

2,019

[]

30,647,145

2,019

[]

30,962,427

2,019

[]

31,552,875

2,019

[ { "contexts": [ "Furthermore, we demonstrated that HCH directed microglia polarization towards anti-inflammatory M2 polarization. " ], "name": "THERM" } ]

31,683,589

2,019

[ { "contexts": [ "Reactivation of HBV infection is a life-threatening condition observed in patients with CHB receiving chemotherapy or other medications. ", "Furthermore, DNA damage leading to the activation of ATM and ATR transcription, results in the reactivation of HBV replication." ], "name": "THERM" } ]

31,820,523

2,019

[ { "contexts": [ "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "SHIPS" }, { "contexts": [ "Extending Surface-Enhanced Raman Spectroscopy to Liquids Using Shell-Isolated Plasmonic Superstructures.Invited for the cover of this issue is the group of Bert M. Weckhuysen at Utrecht University. ", "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "shell-isolated plasmonic superstructures" }, { "contexts": [ "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "SHINERS" }, { "contexts": [ "The image on the cover shows SHIPS, shell-isolated plasmonic superstructures, detecting the presence of picomoles Rhodamine 6G in an aqueous solution using shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). " ], "name": "shell-isolated nanoparticle-enhanced Raman spectroscopy" } ]

31,283,187

2,019

[]

31,291,359

2,019

[]

31,082,805

2,019

[]

30,929,555

2,019

[]

31,392,503

2,019

[]

31,291,967

2,019

[]

31,672,933

2,019

[]

31,327,325

2,019

[]

31,326,434

2,019

[]

31,556,565

2,019

[]

31,325,348

2,019

[]

30,905,971

2,019

[]

31,067,512

2,019

[]

30,885,103

2,019

[]

30,890,181

2,019

[ { "contexts": [ "Here we employed the random forest algorithm to develop VirMiner, a web-based phage contig prediction tool especially sensitive for high-abundances phage contigs, trained and validated by paired metagenomic and phagenomic sequencing data from the human gut flora.\n\n\n", "VirMiner achieved 41.06% ± 17.51% sensitivity and 81.91% ± 4.04% specificity in the prediction of phage contigs. ", "In particular, for the high-abundance phage contigs, VirMiner outperformed other tools (VirFinder and VirSorter) with much higher sensitivity (65.23% ± 16.94%) than VirFinder (34.63% ± 17.96%) and VirSorter (18.75% ± 15.23%) at almost the same specificity. ", "Moreover, VirMiner provides the most comprehensive phage analysis pipeline which is comprised of metagenomic raw reads processing, functional annotation, phage contig identification, and phage-host relationship prediction (CRISPR-spacer recognition) and supports two-group comparison when the input (metagenomic sequence data) includes different conditions (e.g., case and control). ", "Application of VirMiner to an independent cohort of human gut metagenomes obtained from individuals treated with antibiotics revealed that 122 KEGG orthology and 118 Pfam groups had significantly differential abundance in the pre-treatment samples compared to samples at the end of antibiotic administration, including clustered regularly interspaced short palindromic repeats (CRISPR), multidrug resistance, and protein transport. ", "The VirMiner webserver is available at http://sbb.hku.hk/VirMiner/ .\n\n\n", "Compared to VirSorter and VirFinder-the most widely used tools-VirMiner is able to capture more high-abundance phage contigs which could play key roles in infecting bacteria and modulating microbial community dynamics.\n\n\n" ], "name": "VirMiner" }, { "contexts": [ "In particular, for the high-abundance phage contigs, VirMiner outperformed other tools (VirFinder and VirSorter) with much higher sensitivity (65.23% ± 16.94%) than VirFinder (34.63% ± 17.96%) and VirSorter (18.75% ± 15.23%) at almost the same specificity. ", "Compared to VirSorter and VirFinder-the most widely used tools-VirMiner is able to capture more high-abundance phage contigs which could play key roles in infecting bacteria and modulating microbial community dynamics.\n\n\n" ], "name": "VirFinder" }, { "contexts": [ "In particular, for the high-abundance phage contigs, VirMiner outperformed other tools (VirFinder and VirSorter) with much higher sensitivity (65.23% ± 16.94%) than VirFinder (34.63% ± 17.96%) and VirSorter (18.75% ± 15.23%) at almost the same specificity. ", "Compared to VirSorter and VirFinder-the most widely used tools-VirMiner is able to capture more high-abundance phage contigs which could play key roles in infecting bacteria and modulating microbial community dynamics.\n\n\n" ], "name": "VirSorter" } ]

31,803,068

2,019

[]

31,490,226

2,019

[]

31,292,922

2,019

[]

30,955,970

2,019

[]

33,266,948

2,019

[]

30,580,119

2,019

[ { "contexts": [ "Furthermore, it would be advisable to have redundancy in any conservation measures and wildfire-risk mitigations to ensure that losses due to wildfire on one area do not jeopardize all conservation projects within the landscape." ], "name": "THERM" } ]

30,833,913

2,019

[]

30,926,985

2,019

[]

30,658,313

2,019

[]

37,312,344

2,019

[]

29,101,736

2,019

[]

31,403,823

2,019

[]

30,058,408

2,019

[]

31,695,805

2,019

[]

31,407,115

2,019

[]

30,502,643

2,019

[]

30,823,651

2,019

[ { "contexts": [ "Comparative Analysis of Properties of PVA Composites with Various Nanofillers: Pristine Clay, Organoclay, and Functionalized Graphene.Poly(vinyl alcohol) (PVA) nanocomposites containing three different nanofillers are prepared and compared in terms of their thermal properties, morphologies, and oxygen permeabilities. ", "In the thermal properties, SPT and OMB are most effective when the filler corresponds to 5 wt% and 7 wt% for HDA-GS, respectively, and the gas barrier is most effective with respect to 5 wt% content in all fillers. ", "Among the three types of nanofillers that are investigated, OMB exhibits optimal results in terms of thermal stability and the gas barrier effect." ], "name": "THERM" } ]

30,827,614

2,019

[]

31,327,986

2,019

[]

31,367,745

2,019

[ { "contexts": [ "Using SOAPdenovo2 and 170 Gbp of Illumina paired-end and mate-pair reads, we generated a 2.6-Gbp male Masai giraffe genome assembly, with a scaffold N50 of 3 Mbp. " ], "name": "SOAPdenovo2" }, { "contexts": [ "Using SOAPdenovo2 and 170 Gbp of Illumina paired-end and mate-pair reads, we generated a 2.6-Gbp male Masai giraffe genome assembly, with a scaffold N50 of 3 Mbp. " ], "name": "Illumina paired-end and mate-pair reads" }, { "contexts": [ "The incorporation of 114.6 Gbp of Chicago library sequencing data resulted in a HiRise SOAPdenovo + Chicago assembly with an N50 of 48 Mbp and containing 95% of expected genes according to BUSCO analysis. " ], "name": "Chicago library sequencing data" }, { "contexts": [ "Using the Reference-Assisted Chromosome Assembly tool, we were able to order and orient scaffolds into 42 predicted chromosome fragments (PCFs). " ], "name": "Reference-Assisted Chromosome Assembly tool" }, { "contexts": [ "Using fluorescence in situ hybridization, we placed 153 cattle bacterial artificial chromosomes onto giraffe metaphase spreads to assess and assign the PCFs on 14 giraffe autosomes and the X chromosome resulting in the final assembly with an N50 of 177.94 Mbp. " ], "name": "fluorescence in situ hybridization" } ]

31,267,167

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[ { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" }, { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" }, { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" }, { "contexts": [ "In the intestine, CDCA is further metabolized to generate a 7β epimer, i.e., the ursodeoxycholic acid (UDCA), or dehydroxylate to generate lithocolic acid (LCA). ", "Furthermore, CDCA promotes the release of glucagon-like peptide-1 (GLP-1) in diabetic patients, likely by activating GPBAR1." ], "name": "THERM" } ]

31,302,289

2,019

[]

31,101,036

2,019

[]

31,211,825

2,019

[]

31,497,138

2,019

[]

31,506,792

2,019

[]

31,798,851

2,019

[]

31,350,468

2,019

[]

31,284,313

2,019

[ { "contexts": [ "Furthermore, various supplements have got potentially an influence on the characteristics of depression.\n\n\n" ], "name": "THERM" } ]

31,661,814

2,019

[]

31,597,767

2,019

[]

31,849,524

2,019

[]

30,715,263

2,019

[]

30,927,734

2,019

[]

31,124,039

2,019

[ { "contexts": [ "Furthermore, subgroup analysis stratified by children/adolescent and adult groups showed same trend.\n\n\n" ], "name": "THERM" } ]

31,769,611

2,019

[ { "contexts": [ "Transmission electron microscopy, fluorescence, and Raman spectroscopy are used to evaluate the biodegradation of GQDs. " ], "name": "Transmission electron microscopy" }, { "contexts": [ "Transmission electron microscopy, fluorescence, and Raman spectroscopy are used to evaluate the biodegradation of GQDs. " ], "name": "fluorescence" }, { "contexts": [ "Transmission electron microscopy, fluorescence, and Raman spectroscopy are used to evaluate the biodegradation of GQDs. " ], "name": "Raman spectroscopy" }, { "contexts": [ "Molecular dynamics simulations show intimate interactions between the enzymes and the GQDs. " ], "name": "molecular dynamics simulations" } ]

30,543,015

2,019

[]