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We are committed to communicating the most relevant environmental, social and governance (ESG) topics, through publications, web portals and events, in order to keep our investors informed.

In the case of the Audit Committee, the Board of Directors has adopted a policy for the nomination of its members.

Political, social or economic instability in the regions in which our manufacturers are located could cause disruptions in trade, including exports to the U.S.

SVP level and beyond The Company leadership team is supported by Company’s senior-level leadership and their respective teams, with dedicated business and functional expertise focused on climate-related risks and opportunities or on matters which may be affected by such risks and opportunities, including health, safety, environment and carbon; risk; strategy and sustainability (which includes our carbon ambition, policy and economics teams).

The Group’s activities detailed in the ESG section on pages the Group’s diversity objectives.

Equal pay for equal work: assessments and action We recognise the importance of equal pay and take our responsibility for driving this ambition both within and beyond our organisation.

€committed to 136 health and water projects since 2007 2025 commitment Local sourcing of agricultural ingredients in Africa: 50% increase in volume   Over the past decade, our local sourcing projects in Africa have helped create jobs, supported the sustainable development of the agricultural sector and improved the lives of rural communities.

Since the COVID-safety of its people as its first priority.

Further, such measures could lead to constraints on production and supply and access to new reserves, particularly due to the long term nature of many of Company’s projects.

exposure to a wide range of health, safety, security and environmental risks could cause harm to people, the environment and our assets and result in regulatory action, legal liability, business interruption, increased costs, damage to our reputation and potentially denial of our licence to operate.

We create equal opportunity in the moments that matter.

See the section 'A fair and safe workplace' for further equal pay strategy information.

Geopolitical risk is inherent to many regions in which we operate, and heightened political or social tensions or changes in key relationships could adversely affect the group.

The Committee consists of representatives from the Accounting, Controlling & Risk Management and Internal Audit & Security Departments, along with officers from the human resources, procurement, trading, finance, taxes and IT functions, which are highly relevant to accounting.

I am confident in our ability to continue to meet the urgency of the challenges and opportunities ahead for our clients and deliver on the promise of technology and human ingenuity for all.

> We are advocating a phased transition period to at least safety and provide sufficient time for the regulatory approval and transition to alternative low GWP propellants.

> Discussions took place with governments and policymakers to increase understanding of the business model and regulation of the pharmaceutical industry, to support investment in life sciences and to improve access to new medicines.

These relationships create a “closed loop” in that we have direct access to information at both ends of the card transaction, which distinguishes our integrated payments platform from the bankcard networks.

We believe our patients and society will require products that have the smallest possible environmental impact, without sacrificing medical efficacy or safety.

The sectors in which we operate face increasing challenges to attract and retain diverse, skilled and capable talent.

> Project started with peers in pharmaceutical industry (Energize) to enable access to renewable energy in supply chains with a start in the US and the EU, and plans to expand into less mature markets. Change in raw material or sourcing cost.

The Made Together pillar of the Group’s ESG framework is focused on nurturing an inclusive workplace that offers great opportunities for people to grow and develop.

The climate crisis also poses risks to public health, with rising global temperatures increasing the prevalence of respiratory and cardiovascular disease, changes in water-borne illnesses, allergen distribution and concentration, as well as mental health effects.

Key enablers of our growth strategy include: Our People—As a talent- and innovation-led organization, across our entire business our people have highly specialized skills that drive our differentiation and competitiveness.

Our Watersheds – looks beyond traditional water usage to prioritise the health of local watersheds, especially in water-stressed areas.

Similarly, physical risks such as extreme weather, which may be affected or intensified by climate change, are covered in our principal risks related to safety and operations.

Phase II – the phase of clinical research which includes the controlled clinical activities conducted to evaluate the effectiveness of the drug in patients with the disease under study and to begin to determine the safety profile of the drug.

social security contributions) employer part - Borne Employee taxes paid (incl.

The Federal Reserve also permitted stock repurchases equal to the amount of share issuances related to expensed employee compensation.

Pursuing real-world evidence programmes that improve understanding of disease epidemiology and burden, treatment effectiveness and safety, and health economics.

They need to include safety in all their decisions, support their employees to adhere to the LSCs and lead by example.

Integration Low carbon energy Resilient hydrocarbons For our most senior leaders, remuneration measures are aligned with our strategy, shown above, while maintaining a balance with delivery against the financial frame of our investor proposition, and with our core value, safety.

• Encouraging community involvement by promoting various charitable, philanthropic, and social awareness programs, which fosters a collaborative and rewarding work environment.

It is changing our planet irreversibly, with warming reaching critical tolerance thresholds for health.

Best Buy Health provides digital health solutions in active ageing, virtual care, and consumer health.

Percentage increases for executive directors will not exceed increases for the wider workforce, other than in specific circumstances identified by the committee (e.g. in response to a substantial change in responsibilities).

Cash and equivalents (excluding securities with original maturities up to current and non-current, and Marketable securities and short-term investments (excluding securities): The carrying amounts approximate the fair values as the items are short-term in nature or, for cash held in banks, are equal to the deposit amount.

Long-term incentive The Long-term incentive (LTI) is designed to drive and reward sound business decisions for Company’s longterm health, and to align the Executive Board with shareholder interests by linking rewards to Company’s share price performance.

Mr Kobrine received salary, benefits and pension contribution for the balance of his notice period to 24 January 2021, totalling $48,363.

The S&SC also received regular reports from the CEO and SVP S&OR on operational risk, including regular reports prepared on the group’s health, safety, security and environmental performance and operational integrity.

In addition, we engage in platform trust and safety services on behalf of clients, including content moderation, which could have a negative impact on our employees due to the nature of the materials they review.

Company Annual Report and Form Working with contractors Through documents that help bridge between our policies and those of our contractors, we define the way our safety management system co-exists with those of our contractors to manage risk on a site.

market framework is based on a combination of market sizing, regulation, marketing, PEST analysis (Political, Economic, Social, and Technological), and other factors to create a clear understanding of the addressable market opportunities.

To support this commitment, the Company provides benefits-eligible associates and their families with access to free and confidential counseling through our Employee Assistance Program, as well as free access to Headspace, a mediation and mindfulness app, and also provides regular programming on financial planning and mental-health.

Launched in designed to shape, own and drive talent leadership potential towards destination roles.

Opportunity levels Base salary is set with reference to the scope of responsibilities, personal experience and skills and competitive market data.

We will work closely with NGO Partner Africa on Human Rights audits in Africa Middle East & Eastern Europe region.

We set up initiatives with experts and NGOs where actions are needed – from conducting integrated socioeconomic impact assessments to improving the working conditions of brand promoters globally and embedding human rights in local sourcing initiatives.

Recent developments Stakeholder expectations, including those of employees, towards companies, their Environmental, Social and Governance (ESG) strategies and performance, is on the rise.

The Company engages with its workforce through a number of different channels (as set out in more detail on pages 48 and 49).

Fair and safe working conditions for third-party employees in Nigeria Taking care of our third-party employees is a key focus of our Human Rights practices.

Inclusion and diversity Diversity is integrated across our Code of Ethics and associated workforce policy, and we promote a culture of diversity, respect and equal opportunity, where individual success depends only on personal ability and contribution.

For defined benefit plans, retirement benefits are based on such factors as an employee’s pensionable salary and length of service.

The channels outlined on this page ensure that the Board has direct access to the views of the global workforce; provide meaningful information and data that the Board can use when considering the impact of its strategic decisions on employees; and provide opportunities for meaningful dialogue.

Data management in healthcare is moving beyond storing data, to focusing on extracting insights on population health management and value-based care to improve health outcomes and personalised healthcare.

The services provided by the Company primarily include finance, information technology, human resources and certain other administrative services.

Social – Positive impact in our communities Local sourcing of agricultural ingredients in Africa: Key performance indicator Baseline Measurement/units Key Definitions Scope % increase in volume of locally sourced agricultural ingredients 2020 Growth in the total quantity of local raw materials compared to 2020, reported in a percentage of increase.

There is competition for scarce talent with market-leading skills and capabilities in new technologies, and our competitors have directly targeted our employees with these highly sought-after skills and will likely continue to do so.

If an Executive Director resigns or is summarily dismissed, salary, pension and benefits will cease on the last day of employment and there will be no further payments.

Oil demand rebounded with global oil consumptionc increasing by to 96.4mmb/d for the year (+6.0%) on the back of the economic recovery, supported by the increasing vaccination roll-out and gradual lifting of public health measures.

At the same time, there is a need to reduce harmful emissions from human activity.

€invested in community projects since 2015 Company Africa Foundation The Company Africa Foundation will continue to support the health and well-being of communities in sub-Saharan Africa by providing vital access to healthcare and clean water.

In the programme had reached 1.18 million youths with health information and trained 73,000 peer educators in 30 countries.

Evaluated the approach to governance of risk and recommended to the board for approval the allocation of the principal risks across the board and committees (including climate change and the transition to a lower carbon economy and process safety, personal safety and environmental risks).

• Bernard Looney’s salary will increase by £1,392,519 following the 2022 annual general meeting.

In performance in safety, security and sustainability, the committee will focus on the continued goal to eliminate tier 1 process safety incidents by 2025 and the implementation of Company’s net zero ambition and associated aims and targets.

The impact criteria outlined on page health and safety, environmental, financial and non-financial (such as regulatory impact) criteria and are to be used for assessing risks, including climate-related risks.

See Safety, page Such events or conditions, including a marine incident, or inability to provide safe environments for our workforce and the public while at our facilities, premises or during transportation, could lead to injuries, loss of life or environmental damage.

In addition, in there were no material labour disputes, litigation, or health and safety related fines or sanctions imposed on Company. Discrimination, bullying or harassment of any kind are not tolerated in any aspect of the business, including in recruitment, pay, promotions, training and dismissals.

The lifestyle brand creates trend-forward apparel that allows teens to experiment with their style, while exploring the duality of who they are both on social media and in real life.

We believe that the attraction,  retention and management of qualified talent is integral to our success in advancing our strategies and key business priorities and avoiding disruptions in our business.

Political developments, increased supply from new oil and gas or alternative low carbon energy sources, technological change, global economic conditions, public health situations (including the continued impact of the COVID-pandemic or any future epidemic or pandemic), the introduction of new carbon costs and the influence of OPEC+ can impact supply and demand and prices for our products.

Working closely with payers and providers to understand their priorities and ensure appropriate patient access to our medicines.

> meeting with external legal advisers > meeting with the external auditor > when possible, visits to various sites including R&D centres, commercial sites and operations facilities in the UK, Sweden, the US and elsewhere > access to a reading room which provides information on the Group, including financial performance, pipeline information, policies including the Global Standard on Dealing in Company Securities and rules relating to inside information, investor and analyst reports, and media updates.

Company plc may redeem, at its option, any Class X ordinary share for a redemption price equal to the par value of the Class X ordinary share.

Phase I trials with small groups of healthy human volunteers (small molecules) or patients (biologics) to understand how the potential medicine is absorbed into the body, distributed and excreted.

In addition, Board members obtain information through the Board committees in which they participate and which are also attended by relevant EC members and management representatives from human resources, finance, legal and the business.

In addition, positions we take or do not take on social issues may be unpopular with some of our employees or with our clients or potential clients, which may in the future impact our ability to attract or retain employees or clients.

When considering executive remuneration, the Committee takes into consideration our global workforce, looking to ensure the global total reward offering is competitive, compelling and aligned to our business performance, while supporting a culture where everyone feels valued and included, as outlined in the table on page 120.

As the Company must maintain excess availability equal to the greater of million under the ABL Facility, borrowing available to the Company under the ABL Facility was $248.3 million as of January 29, 2022.

In November plans to future accrual (and removed any salary link) from 31 December 2017.

Access to healthcare: we are working towards a future where all people have access to sustainable healthcare solutions for life-changing treatment.

> Pursuing a flexible pricing approach that reflects the wide variation in global health systems.

Developing an inclusive culture rooted in respect, care and commitment as well as seeking diversity, supporting social mobility, and welcoming and developing talent wherever we find it.

• Review workforce policies and practices, and in particular those that have an impact on talent and capability, diversity and inclusion and engagement and culture (including employee wellbeing).

The Directors believe that the Board as a whole is responsible for gathering views of the workforce and consequently chose not to implement any of the three methods of workforce engagement prescribed in the UK Corporate Governance Code.

In Governance (ESG) strategy, which comprises Diversity, Equity, and Inclusion (DE&I), Financial Confidence, and Climate Solutions pillars, with long-term goals and initiatives to guide our efforts in the years ahead and provide a shared sense of purpose for our work.

Depending on the nature and speed of any such changes and our response, these changes could increase costs, reduce our profitability, reduce demand for certain products, limit our access to new opportunities, require us to write down certain assets or curtail or cease certain operations, and affect investor sentiment, our access to capital markets, our competitiveness and financial performance.

Wider workforce activities Company aspires to offer a well-balanced, progressive and structured approach to reward, with appropriate variations by business area and location.

The vesting of the LTI award for performance period 2019-2021 is subject to Company N.V. performance on four financial measures with equal weight.

We provide a broad spectrum of treatments in many different disease areas, allowing for significant access to patients in need of our innovative medicines.

These frameworks include three pillars -transparency, accountability and the development and attraction of diverse talent.

Free Cash Flow (FCF) Free Cash Flow is calculated as net cash provided by operating activities adjusted for: (i) purchases of property, plant and equipment and intangible assets, and (ii) proceeds from sales of property, plant and equipment Productivity growth Productivity is calculated as workforce in the last three months.

Multilateral and non-governmental organisations (NGOs) Company partners with multilateral organisations and NGOs to deliver science-based health programming that addresses global health issues and supports the delivery of the UN Sustainable Development Goals.

The reporting period of the safety data presented in this chapter is December reflected the 2021 full year period.

In certain deepwater fields Company has booked proved reserves before production flow tests are conducted, in part because of the significant safety, cost and environmental implications of conducting these tests.

We added approximately to our global workforce, creating significant employment opportunities in our communities, and donated $54 million in COVID-19 surge relief.

Strengthening our local talent pipeline An important element to ensuring the success of our EverGreen strategy is having the right people in the right place.

Delivering on the Promise of Technology and Human Ingenuity The power of this unique combination is in full view, for example, at Halliburton, a leader in providing products and services to the energy industry.

Our approach to ESG and sustainability is fundamental to the Group’s long-term growth ambitions, as we continue to build the business into a global online betting and gaming leader.