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the innovation of this study is to investigating a dynamic neck brace rehabilitation device after careful reading of this manuscript i have the following comments the study has its innovation study is good designed and conducted data is good analyzed and presented manuscript is good written in table the maximum relative standard deviation for calculated angle in flexion is at degree flexion and in extension is at degree extension it means that the device is not repeatable in small degree please comment and explain the similar phenomenon happens in table in figure and please explain why using degree but not the other degrees or all degrees for evaluation please explain is it easy to put on and take off what is the moving speed of the actuator it

in introduction contents are not sufficientorganization of the paper is missingnovelty of the research is absolutely missingequations should cite properlylatest papers should include in the references throughout the paper model of game theory is missingfig to needs more quantity data analysisconclusion is very vague

the corrections and suggestions on manuscript content also presented in the attached file the review paper needs english translation corrections some of various parts related sections should been added based on suggestions

methods of abstract supplement specific departments also the p is changed to italics and the extra spaces need to be removed please add traditional chinese medicine treatment on the basis of the two groups please rewrite the keywords in the form of mesh and the general keyword is the first letter should also be capitalized it is recommended to supplement some studies related to traditional chinese medicine whether it is preoperative control or postoperative recovery it is recommended that the baseline data be presented in tabular form and the ethics number and informed consent statement should be supplemented since this study used adjuvant therapy liangxue shugan granules why is there no chinese medicine content from start to finish and what does this chinese medicine granule do

i read with great interest the manuscript entitled upregulation of klotho aggravates insulin resistance in gestational diabetes mellitus trophoblast cells by lin et al in this study the authors used hgtreated htrsvneo cells as a model and concluded that klotho played an important role in ir of trophoblast cells induced by hg which was mediated at least in part by the igfpikaktmtor pathway this work is likely to be interesting in its field of investigation but i have several comments as we know hg treatment leads to the reduction of cell viability and cell proliferation in htrsvneo cells the authors should examine the effects of klotho overexpression and downregulation on cell viability and proliferation in hgtreated htrsvneo cells to evaluate cell sensitivity to insulin the glucose uptake experiment

dear authorthank you very much for your manuscript submission indeed your work is welldesigned however some revisions are needed as your work involves a mass of procedures and data it is recommended to add a flow chart to show all the procedures used in your manuscript at one glance in this regard please do read and the following paper to the references section of the manuscriptwriting a strong scientific paper in medicine and the biomedical sciences a checklist and recommendations for early career researchers biol futur dec doi sz epub jul pmid moreover there are some papers which are very close to your study indeed you have to add theses papers to the references section of the manuscript to have a fruitful discussion sectioncovid knowledge attitude practices and

to explore the value of neutrophillymphocyte ratio nlr in combination with red blood cell distribution width rdw in assessing the prognosis of patients with acute sepsis in an emergency setting the study retrospectively analyzed clinical data from patients with acute sepsis the results showed that nlr and rdw were independent risk factors for the prognosis of emergency sepsis patients and the combined detection of the two levels could help to assess the prognosis of emergency sepsis patients this study has verified the relationship between nlr and rdw and sepsis as well as its clinical value and is highly innovative but the existence of the following problems have a certain impact on the quality of the article please modify one by onewhat is the reason for studying the relationship

my points of this paper as shown below follow it and improve your paperplease make the necessary adjustments to table as soon as possibleplease match the style of the last two references to the othersplease emphasize the current state of surgical procedure application and the importance of this studycould you kindly clarify why patients under the age of were not includedthe paper presentation is not appreciable work seriously to improve the presentation of the paperthe discussion section particularly the comparison of past research results should be improvedfrom the start you must specify explicitly what your study will look at an indepth overview of the subject should be the first part of your introductionit is vital that you define the scope of your research from the start your introduction

comments to the authorafter reading your article i think your research is very meaningfulit was found that the combination of le and hmg intramuscular injection has shown to have adequate therapeutic benefits in induction of ovulation a short treatment cycle and a significant diagnostic rate of pregnancy making it a potential treatment option for pcos infertile patients this research can provide guidance for related researchesthe composition is logical and statements is smooth

in order to break the fixed and unified rigid teaching mode of traditional basketball teaching and training a cloudbased teaching mode of internet of things is proposed through the abnormal flow detection and sensor clustering algorithm of naive bayes the internet of things directional basketball teaching and training system is implemented optimization but there are some small errors in research and analysis that need to be revised to ensure the rigor of the article study the integrated teaching through the development background of the internet of things before explaining these methods what are the main teaching and training aspects of basketball teaching and training in the description of the method of naive bayesian traffic detection first analyze the threat of system security to the basketball training and teaching

with the development of social economy especially the popularization and development of agricultural technology the output of agricultural products in china continues to improve therefore this paper discusses the importance of rural ecommerce development the problems faced by rural ecommerce development and the relevant legal protection of rural ecommerce development the following problems lots of expressions in the paper are not professional enough and need to be modified and revised no detailed description of rural ecommerce legal guarantee measures for the development of rural ecommerce in china main business models of rural ecommerce how to improve operators legal and moral awareness

this paper studied the goaf stability evaluation and handling measures decision by fuzzy theory the topic is very interesting and the paper is well structured before publication some issues should be addressed in this paper fuzzy theory is used to solve engineering problems what are the advantages of fuzzy theory in the process of application the evaluation model of goaf stability and decision model of handling measures are provided therefore the relationship between the two models needs to be explained in the process of establishing the judgement matrix how to determine the specific judgement value and they also need to be explained a comprehensive handling measure is proposed on the goafs of the paishanlou gold mine is it possible to adopt a single handling measure why

this paper addresses the current issue at market sales statistics and proposes a deep learningbased approach to solve the problems in sales forecasting it uses two different neural network models fully connected neural network and recurrent neural network to process structured data and sales correlation data respectively to construct deep neural network for feature representation and then output the results the topic is worth researching but the rest of the paper needs to the improvedthe abstract should be written in one paragraphsome errors in punctuation use commas before semicolons or other punctuations always be followed by a blank space the first letter of the title should be capitalized the literature review a analysis literature should be added and further analysedthe contributions and contribution should be combined not written

for this paper the vehicle queue length traffic flow and average delay are taken as the inputs the first layer of the fuzzy neural network system and the green light delay is taken as the output the topics are as followsi the keyword is not consistent regarding the topic of the paper modify the keywordii the summary does not describe the use of the interface in this paper there are three sentences need to be changediv vehicle queue length vehicle speed change therefore flow will affect the recognition accuracy of the system how to reduce noise errorv results h and oc appeared in the results and discussion there is very graphic evidence in the paper it is suggested to delete them

there are some typos and grammatical errors revision by a proficient english native speaker with a complete please with baqs in the manuscript the motivation of the study should be demonstrated extremely clearly as experimental results are expected

please doublecheck all patient data and if necessary make timely corrections to any inaccuraciesthe image needs to be updated for better typesettingthe manuscripts beginning is illogical the statements required for a context connection are missing from the introductionthe manuscript needs more work to improve the grammar and word choice in this essay experimental animals are discussed if the experiment was approved it should be stated in the manuscriptthere is a disparity in the reference pattern create a paper that is an identical replica of the original and includes some recent referencesplease explain any unclear sentences in the discussion forumthe opening section is missing the paragraph describing the organization of the paper establishment of inflammatory reaction model induced by lps and the activation of trem inhibiting the expression of

regarding image enhancement for intangible cultural heritage visualization this article mentions the use of information entropy as a computational method for image enhancement in this paper the digital twin architecture of gs mode is designed and the effect of the architecture model is tested however there are also some defects here can it be supplemented or modified appropriately information entropy as the calculation and evaluation index of image enhancement plays an important role in the conclusion of the article in order to highlight its role can information entropy be added to the keywords in the introduction this article introduces intangible cultural heritage introduces digital twinning visualization and also introduces image enhancement however this article lacks the description of the innovation in the whole article can it be supplemented

the research contribution is not clearthis section is not clearregarding the selected gait parameters stride length speed and double limb support children with chd showed a significant decrease in the stride length and speed and significant increase in the double limb support when was compared with the normal children during fast walking speed pdiscussion author should simplify and clarify the discussion

observation agreen development in the actual management of enterprises and environmental protection must be given more detail the contributor mentioned that the correlation analysis was performed on data to reduce the multicollinearity problem whereas the major causes of the mentioned problem might be clarified in the articleobservation bwhat is meant by an environmental information disclosure system similarly the contributor has to mention how it helps to monitor the pollution emissions and production behavior of enterprises the social and environmental factors responsible for the accidents could be mentioned in the articleobservation cthe term infor mation must be replaced with information in the following statement evaluation report on environmental responsibility infor mation disclosure of chinese the main contribution of the article is mentioned well but it will be better if

the structure of this article is very reasonable and the writing ideas are clear the article firstly introduces the principle of gisbased regional planning then expounds the landscape ecological planning and then expounds the gisbased regional landscape ecological planning however there are still some deficiencies in the article that need to be revised the following are revisions the second paragraph of the introduction is about the significance of this paper for the research on the green development pattern of landscape ecology in gis regional planning but the content of this part is not very substantial can you add some content in the gisbased regional planning part the core function of figure gis lacks a textual description can a textual description of figure be added to ensure the understanding

the background is not clearexplain more about this paragraphhypothyroidism is characterized being an excessive level of this thyroidstimulating hormone tsh above the upper normal limit and reduced metabolic rate what is the importance of thyroid hormone in this species list the risks of systemic sch

based on his research of tourist impression perception in tourism management of network big data and reviews this paper concludes that the impression perception system of network big data can get the impression perception of tourists more comprehensively and intuitively find the tourism factors affecting tourist evaluation from highfrequency vocabulary language full text is rich in content which clear in structure it is suggested that the questions raised be revised and the revised article can be searched for acceptanceathe background of the introduction needs details are described in more detail to increase the readability of the research background bwhat of the meaning of formula to formula the article needs to give some explanation cwhat are the variables equivalent equations to the variables should be explained dalthough the sentence

according to the discussion and empirical analysis in this paper the authors release strategy for using microblogs is novel and helpful for the netizens emotions adjustment which is better than existing methods i think this paper generated big interest thus this manuscript can be accepted for publication in journal for healthcare engineering with the following minor changes description style material like this manuscript requires structured tables similar or better presentationsin introduction part the author should point out the drawbacks of traditional sentiment classification scheme and introduce the purpose of this paper more extensive section the review of related works is not enough there are some recent related works have not described in the manuscriptthe empirical results should be described and explained clearly to show possible effectiveness of the

this study explored the expression of lncrnas snhg and mir in thyroid cancer and their interaction mechanism and their possible roles in the progression of thyroid cancer some small suggestions areaall the abbreviations should be listed with the full names bsome experimental results are described without assay just say cck or transwellcthe paper just used the emt biomarkers to explain the mechanism is not enough need to predict the possible pathway and verify dexpression of snhg and mir and their impacts on cellular biofunction in this part be consistent with any space before the subtitleerescue experiment is not suitable for subheadings

in this manuscript the authors observed the effect of ctrp the manuscript is interesting and has potential for publication however several points need to be addressed before acceptancethe article requires an extensive english revisioni recommend that authors rewrite the abstract to focus on context purpose methodology main findings and conclusionsis ctrp an effective therapeutic or diagnostic biomarker for future keloid treatmentwhat implications does ctrp have for future researchthe abstract is not clear it lacks the main points of this work i recommend to improve iteliminate the use of unnecessary function words the sample size of seems small whether such a result will produce offsetthe current year is while the authors sample is whether such results have any impact on the current meaningsince this study has passed ethical review

in the abstract alofacitinib was used before treat observation group however she was not the drug mentioned in the title and resultsthe grammar mistakes should be made are the differences within study results and observation groupthe epidemiological characters of mpd should be briefly mentioned ethic approval number must be providedhow to calculate the dose sizeis the data that distributedmouse was mentioned in the whysurvival test and km plot were suggestedare there any missing casesthe baseline data should be providedwhat are the limitations of this study

thank you for inviting me to evaluate the article titled diagnosis of gastric stromal tumor based on double contrastenhanced ultrasound and threephase spiral ct in this paper the authorssummarizes and analyzes the diagnosis of transgastric dualcontrast ultrasound and gastricenhanced ct and compares it with the patients postoperative pathological routine and immunohistochemical results aiming to explore the diagnosis of gastrointestinal stromal tumors by dualcontrast ultrasound and gastricenhanced ct value as such the matter is of interest however the paper suffers for some serious limitswhy has ct examination become a routine gst examination methodhow do all patients perform gastric contrastenhanced ctwhat conclusions can be drawn from table and figure dcusenhanced features of rectal gst were compared with the surrounding normal rectal wall what do table and figure showwhy is dualcontrast

general comment the sampling process and sample size calculation should be reported the authors aim to optimize the available data however it is important to pay attention to the biological relevance of the variables to meet the objective of the study specific commentmethod line authors mentioned that cases were children who diagnosed as anemia by the doctorauthors need to confirm if anemia of these children was diagnosed by physical examination by the doctor alone introduction line in china the researchers have reported the prevalence of anemia among children from to comment to specify the period when the study was conducted line other standard populations comment not common to use the term standard populationsstudy designneed to describe the sampling frame and how the cases and controls were selected the

the tumor microenvironment tme is heterogeneous and contains a multiple cell population with surrounded immune cells which plays a major role in regulating metastasis it is of great clinical significance for the authors to study the relationship between breast cancer and its tumor microenvironment in the current work the authors characterized immunerelated subtypes in the breast cancer tumor microenvironment tme and identify genes which could predict the treatment effect although this is a relatively perfect research work the author has also proved the conclusion from many angles through sufficient data but there are still some problems in the article therefore major revision should be carried outthere are grammatical errors in the article including but not limited to the following situations please correct them it has been reported that

the research work clearly discusses an efficient reconfigurable fir filter design with coefficients optimization using modified bacterial foraging optimization algorithm working style of the manuscript is good for readers and better understanding from one step to another step so changes are required in the manuscript which is described as follows a what is the chemotaxis process mention the chemotaxis process role in modified bacterial foraging optimizations algorithm and specify the limitations and advantages of the methodb the pseudocode of the proposed ccse csdbased common subexpression elimination algorithm is explained well in paper provide correct variable explanation in the pseudocodec in figure graphical example of the first exploration twirl and figure random twirl behavior is represented in graph but the x and y axis details are not present in

interesting work reporting on a statistical analysis on fuzzy fractional factorial design for the optimization of manufacturing process matrix shaper machinehowever i dont feel like recommending publication in its present form indeed it is my view whether the manuscript needs major revision to prepare the description and discussion of experimental resultsintroduction was poor add more literature related to optimization techniques what is essential novelty of propose research discuss about the advantage of fuzzy fractional factorial compare with available models organize the manuscript contributors to journal guidanceauthor added more equations but fail to hold in throughout the work add citation in results and dissuasion conclusion must be in data points

reviewer please cite and discuss more relevant studies in the introduction section to support the research and thesis statement of the current study this manuscript needs careful editing by someone with expertise in technical english editing pay particular attention to english grammar spelling and sentence structure so that the goals and results of the study are clear to the readers please update the conclusion what is the significance and innovation of your research compared with other relevant studies please focus on this issue in the discussion section please focus on the format of this paper provide the background of this study in the abstract section at the beginning for figures and tables the format is incorrect please revise them

the existence of the dual system of rural finance the financial property right system and the development of rural financial market directly affect the income level of farmers in order to explore the correlation between farmers income level and regional financial efficiency this paper uses bp artificial neural network model to comprehensively evaluate the rural financial ecology and farmers income levelthesis topic selection is meaningful on the basis of absorbing academic research results have their own experience put forward their own views make sense the viewpoint of exposition is correct the material is more substantial the narration is well arranged and logical some comments are as follows the existence of the rural financial dual system the financial property rights system and the development of the rural financial market

the research on optimization of english teaching model in universities integrating deep learning is well introduced and explained at the same time the objective in your paper is clear and integrated however your research can be further improved before publication in the introduction section you do not introduce the objective of optimizing english teaching model in universities integrating deep learning however it is recommended to add this objective in the introduction section in order to make this section become more systematic and comprehensive in the section when you introduce effective teaching theory please provide the detailed definition of effective teaching theory g because this concept is essential in the section it seems that you do not explain the reason why the ultimate objective of deep learning is to

the application takes the unreasonable situation of a current marketing system as the starting point to realize the intelligence and visualization of the marketing system combining sensor networks pest marketing theory customer classification theory ai technology and machine learning algorithms dbscan to classify different users electricity consumption behaviours and establish an intelligent agency visualization style is a promising research prospect but before the article is published the following should be improved a introduction of the paper method to rearrange functional logic has format error figure has chinese this is a serious problem please modify and check the full documentation dbscan algorithm is mentioned for classification but the principle of the algorithm is described too but it is recommended that the author supplement the prior statement is not clear

authors ganesh et al in their manuscript cesium tolerance and accumulation in a halophyte sesuvium portulacastrum l reported that antioxidant enzyme activities were up regulated up to mgl cs but decreased significantly at mgl the accumulation of cesium was dose and tissue dependent as evident by higher accumulation in leaves gg as compared to stem gg and roots gg the results suggest that s portulacastrum as a hyperaccumulator of cs could be useful for phytoremediation of cesiumcontaminated soilsthis study is interesting and article is well written however authors need to resolve the following issuesplease write capital l for literfor a general reader please write the complete term before using its abbreviation afterwards write abbreviation of that term concerned however do not write an abbreviation at the start of

the numbering of the sections is not given please resolve the inaccuracy and properly list the numbers assign sections and subsectionssome paragraphs are rather long please condense them and use straightforward languagethe second paragraph of the section discussion is not written in apparently please make this adjustment so that it is cleartable values are inaccurate please resolve this issuewhat are a cr pd and pr in this researchplease rewrite some of the equations because they are more complicatedplease correct the grammatical errors and rewrite the sentence the upper limit of concentrations of cea ca ca ca ca and ca in serum of normal and healthy people were ngml uml ngml iuml uml and uml respectivelythe contribution of the paper is not addressed in the introduction please add the

in this paper authors proposed a consensus model considering both the interactive weights determination and the experts adjustment willing for multiattribute largescale group decisionmaking lsgdm in the three folds the research paper has some innovative and key findings which may significantly contribute into the scholarly literature however there are some major issues which need to be corrected before it reaches to the publication the abstract does not work well an abstract should address these concerns what are you trying to do why what you found and what is the significance of your findings rewrite and improve in introduction and the review of literature need more updating with more recent referencesworks as to have a clear and concise state of the art analysis this should more clearly show the

the following suggestions may be incorporated in the manuscript titled international trade volume prediction method based on deep neural network the submitted manuscript is technically sound and ethically good the abbreviations may be presented in a proper format eg dnn in abstract section format deep neural networks dnn the keyword dmu and ai were unable to locate in the abstract section identify keywords appropriately the notations in the equations may be defined eg equation the axis headers for the figure is missing the titles of the figures figure is to be mentioned in the figure too

this paper compares the characteristics of dance types and communication methods under the regional ecological environment and crosscultural background through data analysis it is concluded that the scale of dance market is constantly showing a steady upward trend in recent years but it will rely more on modern technology the article is rich in content and its conclusions are also meaningful for reference please accept this article after revising the following questionsq please answer what the function of formula in the algorithm part of the article isq please answer the types of dance ecological environmentq please answer the basic steps of weighted least square method mentioned in the articleq please answer what the rbf mentioned in the article is and what its role is

in the face of the dynamic changes of big data data storage and updating are also the key issues in establishing the model based on the above situation this paper proposes an optimized collaborative filtering algorithm based on big data and studies the marketing strategy mode with dynamic data modeling technology particle swarm optimization combined with dynamic modeling technology is mainly used to build models and realize the recommendation function in the dynamic changes of user interests the research results of this paper have important practical guiding significance but there are still the following problems need to check the introduction what is the workflow of chaos algorithm supplement the research status of personalized recommendation algorithm what are the advantages and disadvantages of collaborative filtering algorithm what is the

in the existing research its characteristics and defects should be describedit is more typical and representative to study the utilization efficiency of a land exactly what is the significance towards this study in this contextexploratory spatial distance analysis esda can be divided into two sections global and local autocorrelation please explain how this method is available according to boundary conditionsthe value range of morans i should be analyzed in deep maybe the confidence level and the empirical threshold is useful for you to carry out you explaination herethe economic density of construction land in dehong prefecture is the lowest as is yuankm the economic level of construction land in kunming is times lowest than that in diqing prefecture ranking the third and times higher than that in dehong

this paper is well written this paper studies dance job capture technology from the perspective of visualization requirements the starting point is unique and the program performance is better the authors idea is positive but there are still some problems section of the article mentioned that dance data collection consists of three parts please explain these three parts in detail should as shown in figure in section be changed to as shown in figure in order to make the full text coherent please check for grammatical errors please explain in detail the content of the analysis process is divided into three steps mentioned in instead of just showing the name please explain the advantages of traditional euclidean distance mentioned in section it is recommended to adjust the content

this study validated that tumor cellderived exosomal miramp promoted crc cell proliferation and stemness via targeting rora this is of great significance for further revealing the pathogenesis of crc the overall analysis of another article is complete but some many problems in the article need to be solvedit we recommended to add a summary statement from the end of each section of result partin the sentence as shown on figure a the presence of the markers containing tsg cd and alix were characterized by western blot they should be tsgplease or pmirgl in the ordinate of figure f to pmirgloin vivo and in vitro is suggested to use italics please check the full text and modifythe subtitle miramp promotes crc cell growth and stemness in vivo was suggested

the title of the article is developing an interactive digital book narrative study centered on childrens cultural acquisition in public health the authors used an interactive approach to document the childrens behavior the authors research is meaningful and the method used is relatively new but there are several issues in the article that need to be addressed in contrast to adults childrens thinking is narrative and their world perception is storyline oriented in the process of cognition of this world the acquisition of figurative contextual and direct experiences is superior to the acquisition of indirect ones so narrative thinking has an unshakable role in childrens mental activity it is difficult for readers to understand what this sentence meansthe logic of the abstract description needs to be strengthened and

the authors presented an automated epileptic seizure detection based on a fusion of timedomain frequencydomain and information theory features obtained from the eeg signal then a pso is used to select the set of features however the proposed method suffers from these limitations the list of features should be declared using the same pattern for example the authors described only five features from a total of as they mentioned table could be reformated to include the mathematical formula of each feature the feature type and its name what is the significance of the feature space features the authors did not use any feature reduction algorithm according to the significance of the feature why what about the f measure and the statistical analysis of the results the results section

in this study the authors illustrated the functions of prncr in hcc and revealed the related mechanism via molecular biology experiments the methods are appropriate and well described the points are well discussed and adequately supported by the data the authors should focus on the following commentsthe authors investigated the expression of prncr in hcc cell lines however the cell line used in the subsequent experiments was not declaredin abstract the expression of lincrna prncr has been confirmed as a tumor suppressor is inconsistent with the description in introductionthe authors should rephrase the description of to illustrate their results in detail in abstract and decreased mirp was found in the clinical samples and cell lines the authors should provide related evidences to support their points the authors should

in the past few decades advances in highthroughput sequencing and bioinformatics have made it possible to detect millions of fullscale alterations and to systematically study their role in tumorigenesis and development a comprehensive analysis of immune checkpoint gene expression profiles at the pan cancer level identified treatmentrelated biomarkers based on immune checkpoint blockade indicating that gene classes with the same function can serve as molecular features the author hopes to carry out pan cancer research of corf and apply a variety of bioinformatics technologies and basic experiments to analyze its differential expression and prognosis finally the team found that the expression of corf was significantly different in different cancer types and was closely related to poor prognosis the study of this team suggests that corf may be used

this work deals with the diffusion mechanism of chinas longterm care insurance systeman empirical analysis based on provinces it need to revise in the following waysa what is the applicable scenario of the c o x proportional hazards model and it would be better if the following situation were clearly explainedb some references are undercited or lack of important literature so it is recommended to supplement and update them try to refer latest papersc route selection of policy diffusion based on the political model of the american federal system stone pan and walden divided horizontal diffusion and vertical policy diffusion into horizontal diffusion and vertical diffusion these two models should be described to expand the relevant research of chinese scholarsd the reference on the background of chinas aging

my manuscript introduces a dualmode training equipment based on gesture memory algorithm it is interesting and the equipment is practical for treatment of dysfunctional fingers i suggest a minor revision on one paper and give some suggestions the label of ca c d should be presented more clearly did the paper do parallel experiments in gesture recognition

how does this study will propose a wireless sensor network that uses air and nonair conduction to deal with machine english oral pronunciation noise which has a set of appropriate sensor configurations to increase the naturalness and intelligibility of the speech of a machine what is a oee sampling sensor matching arrangement and internal circuit design are all optimized in this research when does it requires extra effort selfstudy evaluation system for spoken english has been developed by combining said english speech assessment with oee accuracy detection explain about the voice signal processing and hardware circuit design make up the bulk of this system explain about a sound sensor how it is used to capture pronunciation information from spoken english what is an automated pattern recognition and modern

the authors found that lncrna neat promotes angiogenesis in retinoblastoma through the regulation of the hifvegf axis via mira the research is innovative but i have some concerns the language of the whole manuscript needs to be modified was there any previous study on the mechanism of neat in rb why choose neat the p value is missing in the legend please supplement the p value of all figures the discussion needs to be enriched what are the limitations of this study why did you choose y as the cell line for the followup study selecting only one cell line is not enough to support the experimental results primer sequences should be placed in the table the tube formation assay requires detailed steps

the article has the following problemsthe article needs to give the size of the data set and the training set and test set in the experimental chapter to facilitate the reader to further understandthe authors have a more further description of the work plan for future researchrelated work is needed to give artificial intelligence models and their relevance to graphic designthe authors need to briefly describe the motivation for this paper in the introduction section

the abstract for his article needs to be reorganized it is necessary to reflect on problems are methods research research results conclusions and significance you have based on by introducing deep learning algorithm your research gives full play to the advantages of using bp neural network image processing and uses the spatial information of remote sensing images to extract information from remote sensing images on lakes and reservoirs suggest to further elaborate your innovation and contribution in the introduction it may also necessary to introduce the original premise and techniques of deep learning in the simulation and prediction of landscape pattern and model of wetland nature reserve as well as the application ideas of deep learning technology how to apply deep learning to the simulation and prediction of

this article is devoted to project scheduling problem and manpower allocation considering the skill level a multiobjective optimization problem with three objectives is proposed the problem is solved by mopso and nsgaii the computational results show its great performance this paper is very interesting after a careful review of the manuscript i have the following comments in the title it is said a hybrid meta heuristic algorithm mopso nsgaii is proposed however the manuscript only provides the results with these two algorithms how these algorithms are hybrid in the abstract last paragraph of section and section the authors mention incorrect sortinguncoordinated sorting and a multiobjective particle mass optimization method i guess the incorrect sorting is stand for nsgaii and a multiobjective particle mass optimization method refers to mopso

this manuscript entitled related molecular mechanism of mitogenactivated protein kinases transforming growth factor tumor necrosis factor receptor associated factor signaling pathway changes in patients with atrial fibrillation had described the molecular regulatory mechanism of mitogenactivated protein kinases mapks transforming growth factor tgf tumor necrosis factor receptor associated factor traf signaling pathway in the process of atrial fibrillation the topic and content of this study are of novelty and interest however some minor revisions have to be made before publicationin part in this study patients with rheumatic heart who underwent cardiac surgery at the heart surgery department of xxx hospital from july to march were selected as the research subjects the name of the hospital is not showing please include it in the revisionin part after adding the isopropanol

in this work the authors investigated a mechanical and water absorption study of graphene fiber titanium diboride tib and epoxy resin graphene fibertibepoxy nanocomposites by response surface methodology rsm the subject of the manuscript covers the journal aims and may be interesting for the readers the synthetic and experimental parts are clear and understood characterization parts need more instrumental analysis despite current investigations so the current version is not acceptable and must clearly change both new references in the field and analysis as suggested below then after stepbystep deep changes it can consider againpage introduction parts are short the main part for readers is introduction they need to find out why the authors selected the experimental and why this manuscript is important so the composite and nanocomposite importance

why hexagonal boron nitride hbn nanoparticles is used in this study of researchwhat type of roughness tester is useduse abbreviation only for the first timethe initial letter of each notional word in the paper title should be capitalized however the words forto and the should not be capitalizedrestructure the conclusion

dear editor the problem definitions and the way of dealing with are based on ordinary problem solving using general methods so it is needed to be complicated and elaborated by modern techniques ie modern mathematical neural network optimization algorithms to get some new insights commentsthe manuscript language should be regarding shock and vibration principles so it should go revised and especially without the author affiliations the title is general and does not indicates the specifications and metrics of the research it should be reconsidered to get the ultimate meaning of the researchthe abstract part was not well chosen and needs to be revised again to declare as introduction description and conclusion quantitively not qualitatively only more quantitative results must be reflected in the abstract the finite element model

in the present report crosssectional study on type characteristics and drug resistance of haemophilus influenzae in kunming children mei yuan and xiaoli he investigate the epidemiological changes the drug resistance patterns of haemophilus influenzae viral in children in kunming so as to provide guidance and clinical treatment they also infects children primarily through the respiratory routetheepidemic capsular typing in this area is nthi the epidemicbiological typing is ii and iii while the epidemic resistance phenotype is lactamase positive ampicillin resistance blpar nevertheless the work in its current form has several limitations that make publication about computational and mathematical methods in medicine the author indicated the epidemicbiological typing in ii and iii and the epidemic resistance phenotype is lactamase positive influenza resistance blpar what about type ithe description septicemia

the methodology of the proposed work becomes interesting and unique although there is merit need some minor changes in the paper before publication the abstract of the proposed methodology becomes interesting proposed work consists of three main challenges are identified to classify feelings in indian language tweets and possible methods for tackling such issues firstly it has been found that the informal nature of tweets is crucial for the classification of feelings based on the tweets the mental illness of the person has been classified therefore to categorize indian language tweets is proposed a combination of grammar rules based on adjectives and negations this type of categorization is unique and has a good way of explanation a technique called field tags is used to include nongrammatic arguments such

this paper discussed the optimization of surgical anesthesia information management systems based on bs threelayer architecture by using ai techniques the following suggestions can help to improve the paper redraw fig for proper vision and increase the quality of fig add the contribution and paper organization to the introduction for more understanding it is recommended that the authors do a thorough literature review and explain the dataset proper manner add the table for tuned parameters of the ai algorithm it will improve the understanding of how ai algorithms relate to this article compare the results with other techniques results it advises organizing references in a proper manner minimize the grammatical errors on pages and

reviewer minorthe content of the search strategy should be needed more informationthe figure should be clearerplease except that the format of the full text are consistent such as whether the initial letter of the subtitle is capitalized and whether there are spaces before the paragraphthere are some typos in one article please correctthe content of the methods and results in the abstract was not enough please all references are ten years ago please use the new onethe full name of several abbreviations should be given in the figure legendin the discussion the author can use some brief words then add and describe the background knowledge related to this paper and so describe its experimental results and the advantages and disadvantages of this paper

this paper uses the convolution neural network approach to design and execute the three elements of image processing feature extraction and picture reconstruction to complete the pixellevel object detection of remote sensing images the authors of this study developed and implemented a model based on the secondorder feature fusion technique to address the issue of inadequate decision information to convey lowlevel information this model employs the encoderdecoder structure because the testing findings are good i recommend minor revision with the following suggestionsmy first point to consider is the abstract of this study although this abstract is wellorganized i have detected a few irrelevant sentences and insufficient connectivity between these sentences as a result i propose that the abstract be rewritten and the aforementioned flaw is correctedin most of

the abstract does not reflect the relevant methods of ai deep convolutional network should we simply describe the techniques and methods used in this research in the abstract so that a complete summary can be formedin the preface there are three paragraphs in total among which two ends describe breast cancer the third paragraph introduces the technology in a short length and this research focuses on the technology of ai deep convolutional neural network doesnt it please add to this in the third preambular paragraphwhile method elaborates on mammogram calcification criteria it does not cite relevant literature so where did you get this criteria results the roc curve in does not have relevant statistical values please complete the supplementgeneral information to supplement the case datadelete meaningless blank lines

the number of positive lymph nodes can be a simple and effective prognostic indicator of gastric cancer the authors applied indocyanine green icg tracing and ex vitro anatomical sorting to lns dissection to increase the detection rate of lymph nodes lns in radical gastrostomy and explored the guiding role of lns number detected in the prognosis of patients with gastric cancer gc the work itself seems to be sound however it needs necessary revisionthe discussion section can be more indepth such as the innovation and deficiency of this articleminor concernsfigcd add correlation coefficient r to indicate the correlation exists between total ln number and positive ln number fig the number of total lns is and the number of lns with positive icg is icg stained lns accounted for

since it has passed the ethics review please add the ethics number i am curious that cases of acute myocardial infarction ami group cases of unstable angina pectoris uap group and cases of stable angina pectoris sap group why is it grouped like this instead of the same number of each group in this way there are multiple variables and different samples cause bias why the patients basic information such as high blood pressure diabetes smoking and other factors should have an impact on the patient although this study was not statistically significant i recommend that the analysis be placed as a separate section

confidential comments to the editors there are some problems with the study design and this manuscript was revised and reviewed comments to the author this study aimed to an analysis of the clinical effects and immune function of aerosol inhalation of recombinant human interferon b for the treatment of respiratory syncytial virus infections in children the research found that aerosol inhalation of recombinant human interferon b has a remarkable clinical effect among children infected with respiratory syncytial virus it is not only effective at reducing inflammation in children but is also effective at improving their immune system but several concerns should be addressed the manuscript need to be modified and polished by native englishspeaking medical professionals and relevant proof should be provided page the content of the introduction

this paper analyzes the relationship between gsdmb expression and each tumorinfiltrating immune function using the gene module of timer database in great detail but some problems exist in the textthe results in the abstract the our data showed that normal expression of gsdmb in tumor tissues within ovarian cancer patients was significantly lower than that in paracancerous tissues and the gsdmb gene were significantly correlated with the degree of immune cell infiltration which could be revised without further downward extension by the authorsthe article mentions that ovarian cancer is one of the two common malignant tumors of the san reproductive system but it does not mention how it is caused by the cause of cancers so the authors are likely to addwe used the cibersort algorithm httpscibersortstanfordedu to

a description of general demographic characteristics and postoperative complications argument isnt good enough to justify useful work on it some morebclearly mention the references in the introduction work together arrange them in a logical waycthe presentation over the manuscript is not good the presentation of the paper need some workingdclearly describe the comparison of harris profiles between the two groupsethe initial sectionbysection research is inadequate please update the introduction section to include sectionbypart study specificsfthe abstract has to be significantly enhanced make the initial few sentences more concise and comprehensive when rewriting themgthe first table is absurd adjustments should be made in a straightforward mannerhadd for more information in the collection of general information section

the main novelty of the science paper is to reduce the size on video containers that use the rgbcolour model by applying a similar technique as multifoldunfold algorithm which is used forfolding video frames multi times where the folded frame is used comments are as follows at the same time language or writing still needs to be polished where some grammar errorsexist and some syntax does not meet the requirement about scientific paper that theauthor of this paper must work over the quality with the equations and improve the language the introduction of the proposed work is clear however the main motivation for the proposedmethod still in mind for more clarification so the author should add one or two paragraphs toclearly state the motivation the paper needs to

this paper presents a review study of click model which from the perspective of probabilistic graph model and neural network overall this is a fundamental research the presented literature identification process is sound and the findings support the research questions however there are some details should be modified prior to publicationfirstly in the main problems section the paper points out that data sparsity is a typical problem but it is not a problem that has not been paid attention to related works below should be discussed and citedlin j liu w dai x zhang w yu y a graphenhanced click model for web search sigir the th international acm sigir conference on research and development in information retrieval acmsecondly in the future directions of using eyetracking equipment in

please proofread the manuscript language by someone who specializes in english writing the hospital mentioned in the method is the whole hospital or a certain department the authors abstract is topheavy the purpose of the abstract is to succinctly tell the reader what the study did and what the conclusion was instead of blindly copying the resulting data it is suggested that the author refine the abstract adjust the abstract number to about words and strengthen the description of the conclusion part also p is changed to italics extra spaces need to be removed the abbreviations needs to be given the full name such as nrs score please rewrite the keywords in the form of mesh and the general keyword is the first letter should also be capitalized

this is a very interesting study which investigated biomechanical strength of cementedaugmented screw fixation their results presenting biomechanical strength of cementedaugmented screws according to various designs will be clinically helpful for spine surgeons who plan surgery for patients with osteoporosis

based on the decisionmaking function of knowledge map this paper analyzes the research and evolution of community governance in china and introduces the technologies and methods of entity identification knowledge map construction cluster analysis and decisionmaking model construction combining traditional rulebased decisionmaking with knowledge map can analyze and solve problems the research content of this paper is innovative but there are still some problems that need to be adjustedhow to understand community governanceexplain the elements of knowledge map constructionwhat is the core link of constructing knowledge mapwhat are the research hotspots of community governancehow to understand the construction process of knowledge mapexplain the development of community governance

protective effect of quercetin on myocardial injury and high mobility group box in rats with sepsisto explore the mechanism of quercetin que on myocardial protection in rats with sepsisinduced myocardial injury and its effect on hmgb metabolism wistar rats were selected and divided into groups firstly observe the toxicity of quercetin in rats and evaluate its safety then the animal model of sepsis was used to observe the effect of safe dose of quercetin preadministration and delayed administration on improving the survival rate of animals finally the effect and mechanism of quercetin on hmgb release and proinflammatory function were discussed by comparison at cellular level the author needs to revise the following questions to make the manuscript more perfecti in the abstract the author mentioned that the experimental

ithe papers sections may be lacking the presentation of the paper may benefit by a few tweaksiithe papers part must be wellwritten but welldescribed please rewrite a selection sentences in the abstract areaiiiarrange the references in a similar illustration also help cite them in the introductionivrevise it with the aging of the population in china the incidence of gastric carcinoma shows an increasing trend year by year vits possible that the introduction section will be quite brief please update the section titled those the main headings add a couple lines labeled materials and methodsvii the introduction section lacks a sectionbysection analysis in the introduction area please upload the paper section by a paragraphviiiin the treatment method for patients with gastric carcinoma peritoneal metastasis the second paragraph update them

as a prospective clinical trial its registration number needs to be mentioned in the introduction section it is suggested to discuss in sections to better understand the research background as with the previous comment the discussion section should be improved

this study is a quit simple study there other questions to be answeredthe language should be polishedwhich pathway is affected by circspecc this should be detectedthe ethic approval number should be providedthere are some many circrnas why circspecc was selected figure f and g seems not consistentthe results of wb should be reevaluatedin conclusion more data are needed to confirm the role of circspecc

thank you for inviting me here evaluate this manuscript this article from your new analysis indicators explore women may occur gynecological problems treatment effect is excellent i suppose it can be published in journals as soon as able so i put forward some suggestions for usage of this manuscriptregarding the use of section headings you also need to consider changing the headings which can also be used page headings for other sectionswhile the point of the article is well stated consider cutting short some irrelevant introductions to make the article more focusedalthough these observations are interestingthey are rather limited and are not advance our knowledge of the subject sufficiently to warrant publicationthe discussion my conclusions are well balanced and adequately verified by the data i recommend acceptance after

following are the minor edits that the authors should address abstract is too long and needs a thougrohou revision section heading and numbering should be checked ie section introduction related work material and methods results and discussion and conclusion and future work in section authors claimed patients received conventional fluid resuscitation while the other one was given restrictive fluid resuscitation combined with vitamin c justify both groups of patients after routine treatment including strong broadspectrum antibacterial antiinfection treatment no proper literature support is provided to justify the treatment during intravenous infusion of vitamin c why the manufacturer jiangshan pharmaceutical batch no h is used why not others authors should first introduce necessary tests and then provide a mechanism eg hemodynamic testing serum test etc in section observational indicators

at present the research on the administrative legal regulation of social risks related to artificial intelligence in chinas administrative law circles is still in its infancy through artificial intelligence entering the administrative process and theory of risk management law in the legal regulation of social risk management it takes the lead in constructing the theoretical system of artificial intelligence social risks based on this this paper has obtained effective conclusions through research which provides a direction for the future development of learning in this field the article closely follows the theme and meets the professional requirements it is suggested to revise and improve the following questions so this article can be hireda the background of the thesis is not reflected in the abstract and introduction so it is

this is a carefully done study and the findings are of considerable interest a few minor revisions are list belowin the figure legend the p should be addedin the table legend there are some wrong data the authors should correct themin the introduction the reference cell transplant aug should be citedthis article can be accepted after minor revisions without rereview

praise you for inviting me to evaluate this manuscript this is a novel and mature article it pays attention to the puerpera and solves this problem well you only need here fix a few minor issues and therefore can publish without any problems in the abstract part at the beginning of this article the content level but not clear enough its logic is not rigorous enough and the content is simply stacked also the number of keywords listed for the article is too high the groups of keywords should be five by six please further check the experimental method in the article which is not seen in the corresponding part of the article and then compare and analyze the methods this article has some problems in the presentation

first of all thank you for submitting your valuable clinical study to this journal let me give you a few comments the word innovative technique doesnt seem right there is no innovation abstract doesnt even match the word novel it is thought to be a case of endoscopic surgery by reducing only the incision without anything new it is a fact well known to any surgeon who reconstructs ld flaps that the volume is insufficient to make breasts with only the ld muscle most of the figures you showed do not have longterm fu and at months after surgery the patient with the picture has a small breast but the reconstructed area is so small that it is difficult to think that the breast has been reconstructed for

i suggest to the authors please improve the language of the section the potential role of wntcatenin pathway crosstalk in resistancethe introduction makes no indication of the papers structure as a result in the opening section please offer a sectionbysection examination of your findingswhy the wntcatenin pathway is necessary for both developmental and adult tissue homeostasisfix any typographical and line spacing mistakes in the manuscriptthe discussion in this article is rather lengthy and does not effectively summarise the suggested work paper create a more advantageous environmentwhat are the esophageal cancer and wntcatenin signaling also give some detail about thislittle more work on the role of mucin in development of cancer sectionthis works final reference list is presented in a picturestyle format to solve this problem kindly take your

the authors defined parametric kinds of bellbased frobeniustype eulerian polynomials by introducing the two specific exponential generating functions and obtained some implicit summation formulas differentiation rules and correlations with the earlier polynomials by utilizing some series manipulation method moreover the authors constructed tables containing the zero values of bellbased frobeniustype eulerian polynomials and drew several graphs depicting the zeros of the polynomialsthe paper is well written and results are new and significant which are original contributions to this area of research i therefore recommend for the publication of the paper to the journal of function spaces subject to inclusion of the following references related to the present study the estimation of the zeros of the bell and rbell polynomials applied mathematics and computationvolume january pages an asymptotic formula

reviewer this manuscripts target problem is quite interesting and applicable butseveral comments are provided below for revision abstract section needs some modifications the background of study to be provided in a couple long sentences in the beginning end this paragraph with a concluding statement and its length should not contain unk please check your paper according to the template carefullyespecially pay much attention to your references the figures and tables it should be noted that this page needs careful editing by someone with expertise in technical english editing pay particular attention to english grammar spelling and vocabulary structure stressed that the goals and analysis of the discussion are clear to the readers information i suggest that the author modify the article again the title needs to be capitalized

in the paper efficacy and safety of laparoscopic radical hysterectomy for pelvic breast node dissection on patients with early cervical cancer this paper is almost very detailed and i suggest to the authors please change yours a little more according to my comments that are given belowdefine more detailed the following section comparison of anal exhaust time and postsurgery hospitalization across both cohorts pay close attention to english faults in the text but check them and enhance your english understanding are the control cohort patients please definecan you mean pelvic lymph node dissectionpresent the theoretical foundation for the investigation in a clear manner using current research referencesthe introduction should also provide information about the researchs context id like you to hold attention to it because its missing a

dear author your manuscript is well written and justified to the given title but missing the novelty also compile it with respect to reported case studies kindly revise it with few of the below commentscommentstitle looks inappropriate from the publication point of view give some catchy and meaningful title there are many typographical as well as grammatical errors in the manuscriptmanuscript presented is moreover looks like a textbook chapter rather than the review article many case studies as well as examples of previously reported studies are missing in each area presenting similar reportscase studies will be the value addition in this articledata presented in this review is not novel its mostly compilation of the data improve the manuscript with novelty in types methodology and characterizationsreference seems to be

following are the comments for the paper the development and digitalization of cultural industry marketing based on big data supplement the research results of this paper in the abstract chapter is not the focus of this article there are too many descriptions delete them appropriately in chapter there is little analysis of chart data supplement it appropriately chapter is one of the key parts of this paper but the content is less supplement it appropriately there are less than references supplement them

research published in the journal must bethe topic addressed by the authors is in scope with those of the journalthe topic addressed by the authors has been extensively documented in the literature and the proposed solution is a variation of known methods nevertheless the formulation of the proposed solution is correct and the numerical results seem consistentgiven what was noted above and given that the authors took into account the guidance given to them by previous reviewers i believe there is no further indication against publishing the paper

zhang et al in the manuscript circular rna circhipk attenuated m macrophagemicroglial polarization and contributed to cerebral ischemiareperfusion injury of astrocytes by targeting micrornaptlr axis identified a new function of circular rna hipk in regulating astrocyte injury and microglia m polarization the research is in scope of the journal and scientifically valid the novelty of the manuscript is high the work is ethically sound but i suggest adding more details for the in vivo experiments it is technically quite accurate in its methods and results the following criticisms should be addressedthe authors should perform a coculture of microglial cells and astrocytes in order to better analyse the effects of microglia polarization on astrocytescan the authors hypothesize a mechanism of communication between microglial cells and astrocytes mediated by extracellular

in this paper the fixed point of miscellaneous functions obtain by using a fresh repetitive method in a word the obtained results of this paper are new and novel i recommend this paper to be published after making the following changes you should find related articles such asa httpsdoiorgsyb icciautomc httpsdoiorgsyd httpsdoiorgsxadd to the resources section all equations must be putted comma or point according to the typing rules therefore they need to precheck all the paperthe novelty of the article should come in the introduction review on the proposed approach isnt explained clearly

in order to meet the new demand of crime hot spot prediction in the era of big data this paper proposes a crime hot lane data prediction technology based on arimalstm model the arimalstm algorithm be used to extract the statistical characteristics of crime hotspot data by combining real data and stgn model a model suitable for predicting the spatiotemporal characteristics of traffic hotspots is used to improve the level of crime hotspot data for the experimental results concluded that the proposed method has high analytical efficiency lower error rate and stronger superiority than other methods even writing content of this paper is novel and the method is refined but there are still the following problems a it is suggested to replace spatiotemporal data warehouse with data warehouse

define completely the personal learning techniques for medical imaging applicationswho is the best method in confirm the diagnosis in the patients please definethe papers organization is missing from the texts initial sectionthe work has several repetitions and duplications which calls for a thorough linguistic reconstruction the overall language of the soft learning and cardiac diagnosis because its terms are so highadd some advanced detail in the comparison of lesion classification accuracy sectiondefine are deep neural network and describe the uses of the deep learning medical processingfigure has to be made just so that it is clearer it is now difficult to graspthe purpose of the research should be read in the beginningplease use plain english within the connected work part as the terminology in the experimental and result

there are many small problems in the writing of this article for example the method part in the abstract is too simple after reading it i cannot fully understand the research method used in the article the discussion and conclusion sections are also poorly written the detailed questions are as follows which can be carefully modified by the authorsgenerally there are four things included in the abstract backgrounds methods results and conclusions in addition the abstract should not exceed words there are too many statements regarding background in the abstract the main research results should be summarized scientifically using quantitative data please rewrite the abstract section please explain fuzzy cognitive maps in abstractsimple keywords are betterplease reformat the manuscript according to for authors of biomed research internationalstudies on

in order to explore the role of ectonucleotide pyrophosphatasephosphodiesterase inhibitors in promoting the regression of vascular calcification in rats and to elucidate its mechanism rat thoracic aortic vascular smooth muscle network they are divided into the experimental group the model group and the normal group respectively a few minor revision are list belowthe wording and style of some section particularly those concerning vsmc need careful editing attention should be kept to the content of those parts of the discussion of and summary which have been underlinedalthough this paper is good it would be ever better if some extra data are added since these observation are interesting however are rather limited and do not advance our knowledge of the theory because these warrant publication in vsmc we feel that

acknowledging the work of authors to lifestyle improvements and vitamin d supplementation play an important role in the prevention of childhood diabetes does provide insights into the field however a major challenge i do envision with this work is the novelty therefore this manuscript needs major revision and i am recommending authors to work on the above mentioned points the english of your manuscript must be improved before resubmission we strongly suggest that you obtain assistance from a colleague who is wellversed in english or whose native language is englishi would be very glad to rereview the paper in greater depth once it has been edited because the subject is interestingplease note the format of the manuscript and do not bold the authors namewhether the vitamin d used

the authors proposed an interactivebased pulmonary nodule segmentation aiming to be used in clinics and trained from small datathe proposed approach is generally promising however i have several concerns major comments the authors provided an ablation study on the network design however the reader could not see the ablatio study while correcting the segmentation results interactively when a correction is needed how much time does an expert requireto correct the wrong segmentation it is not clear how an expert would modify the segmentation by providing nodes please elaborate on this the authors did not provide how the training validation and testing data were used did you need the nodes from an expertfor the test set line could you please support with references this is not generally true what