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### Instruction: What sentiment polarity is expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''$arwr changing how we prevent cardiovascular and renal disease olpasiran, small interfering rna molecule reduce lp(a) better than placebo (ocean(a)-dose)? sun, nov 06 5:00pm - 6:00pm (central). '''### Response: The sentiment polarity expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' transform-hf: placebo effect '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''transform-hf - a large pragmatic rct of furosemide vs torsemide. no evidence of difference in mortality or hospitalisation. but a great demonstration that pragmatism is an essential & beneficial feature of good rcts. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term dcp in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''another pragmatic rct dcp result @#aha22 chlorthalidone vs hydrochlorothiazide - no difference in incidence of major cardiovascular outcomes again, an efficient way to get reliable evidence in a broad range of patients '''### Response: The sentiment polarity expressed regarding the given aspect term dcp in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term empa-kidney in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''david preiss presenting results of empa-kidney trial #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term empa-kidney in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term OCEAN(a) DOSE in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ocean(a) dose-finding trial of olpadiran, a small interfering rna, showed >95% reduction in lp(a) in pts with median lp(a) approx 260 nmol/l and established cardiovascular disease. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term OCEAN(a) DOSE in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term pemafibrate in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''pemafibrate va placebo on top of ldl-lowering treatment in pts with high triglycerides and low hdl-cholesterol in diabetic pts. a debate as long as my career. despite 20-30% reduction in triglycerides, no impact on major cardiovascular events. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term pemafibrate in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''really important to see this practical transform-hf trial and now we have the data to guide our debates on which loop diuretic: (answer: use what works for your patient and focus on decongestive #gdmtworks- compliment with sglt2i, arni, mra for k sparing). monitor carefully. '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ecmo-cs in patients with rapidly deteriorating or severe cardiogenic shock, immediate use of #ecmo does not improve outcomes over an initially conservative strategy with bailout ecmo as needed #aha22 #heartfailure #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term EMPA-HEART 2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''empa-heart 2 cardiolink-7 this study demonstrated that in people without #t2dm , 80% of whom had a dx of htn , but with an average baseline blood pressure of 135/80mmhg, and low baseline nt-probnp/no significant #heartfailure #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term EMPA-HEART 2 in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term advor in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''a pre-specified analysis from the advor trial results from the present analyses demonstrate that the treatment effects of acetazolamide in patients hospitalized with acute #heartfailure are not modified by lvef #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term advor in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term acetalozamide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''a pre-specified analysis from the advor trial results from the present analyses demonstrate that the treatment effects of acetazolamide in patients hospitalized with acute #heartfailure are not modified by lvef #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term acetalozamide in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term empa-kidney in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''in case you spent all of #aha22 day 2 in the puppy pen: ischemia-extend: sport: empa-kidney: precise: ocean(a)dose: bright-4: '''### Response: The sentiment polarity expressed regarding the given aspect term empa-kidney in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ocean(a)-dose in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''in case you spent all of #aha22 day 2 in the puppy pen: ischemia-extend: sport: empa-kidney: precise: ocean(a)dose: bright-4: '''### Response: The sentiment polarity expressed regarding the given aspect term ocean(a)-dose in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term precise in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''in case you spent all of #aha22 day 2 in the puppy pen: ischemia-extend: sport: empa-kidney: precise: ocean(a)dose: bright-4: '''### Response: The sentiment polarity expressed regarding the given aspect term precise in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term sport in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''in case you spent all of #aha22 day 2 in the puppy pen: ischemia-extend: sport: empa-kidney: precise: ocean(a)dose: bright-4: '''### Response: The sentiment polarity expressed regarding the given aspect term sport in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ischemia-extend in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''in case you spent all of #aha22 day 2 in the puppy pen: ischemia-extend: sport: empa-kidney: precise: ocean(a)dose: bright-4: '''### Response: The sentiment polarity expressed regarding the given aspect term ischemia-extend in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ischemia-extend in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''extended f/up of the ischemia-extend trial over a median 5.7 yr demonstrated that an initial inv strategy compared with an initial con strategy resulted in: no difference in all-cause with nearly twice the number of (557) lower risk of cv higher risk of non-cv #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ischemia-extend in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term indobufen in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#originalresearch simpub #aha2022 #circaha22: in this #rct, indobufen + clopidogrel dapt compared with aspirin + clopidogrel dapt significantly reduced the risk of 1-year net clinical outcomes, mainly driven by a reduction in bleeding events without an .... '''### Response: The sentiment polarity expressed regarding the given aspect term indobufen in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term clopidogrel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#originalresearch simpub #aha2022 #circaha22: in this #rct, indobufen + clopidogrel dapt compared with aspirin + clopidogrel dapt significantly reduced the risk of 1-year net clinical outcomes, mainly driven by a reduction in bleeding events without an .... '''### Response: The sentiment polarity expressed regarding the given aspect term clopidogrel in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''early ecmo-cs no better than watch-and-wait approach in #cardiogenicshock the ecmo-cs trial of patients with rapidly deteriorating or severe shock suggests ecmo can be held until hemodynamic status worsens #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ischemia-extend in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ischemia-extend even with a few more years of follow-up, an initial invasive strategy is no better than a more-conservative approach for improving survival in patients with chronic cad and moderate to severe ischemia #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ischemia-extend in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term EMPA-HEART 2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''empagliflozin and lv remodeling in people without dm : primary results of the EMPA-HEART 2 cardiolink-7 #sglt2i with empagliflozin did not result in any meaningful changes in lv structure or function as assessed by #whycmr at 6 months #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term EMPA-HEART 2 in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term empagliflozin in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''empagliflozin and lv remodeling in people without dm : primary results of the EMPA-HEART 2 cardiolink-7 #sglt2i with empagliflozin did not result in any meaningful changes in lv structure or function as assessed by #whycmr at 6 months #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term empagliflozin in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ecmo-cs in the therapy of cardiogenic shock: results of the ecmo-cs rct primary endpoint from any cause, resuscitated circulatory arrest, and use of another #mcs device at 30 days did not differ between the immediate versus conservative groups (63.8% vs 71.2%; p= 0.21) #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term advor in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''decongestion with acetazolamide in acute decompensated #heartfailure across the spectrum of #lvef : a pre-specified analysis from the advor trial #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term advor in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term acetazolamide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''decongestion with acetazolamide in acute decompensated #heartfailure across the spectrum of #lvef : a pre-specified analysis from the advor trial #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term acetazolamide in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term valor-hcm in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#originalreseach #simpub #aha2022 #circaha22 in valor-hcm myosin inhibition with mavacamten reduced the need for septal reduction therapy at 32 weeks with lvot gradients quality of life, and positive cardiac remodeling #ahajournals '''### Response: The sentiment polarity expressed regarding the given aspect term valor-hcm in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term mavacamten in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#originalreseach #simpub #aha2022 #circaha22 in valor-hcm myosin inhibition with mavacamten reduced the need for septal reduction therapy at 32 weeks with lvot gradients quality of life, and positive cardiac remodeling #ahajournals '''### Response: The sentiment polarity expressed regarding the given aspect term mavacamten in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ecmo-cs summary results from #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term torsemide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''"while we were disappointed that we didnot show torsemide was better, i think we ve answered the question," says #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term torsemide in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' dramatic reductions in lp(a) with olpasiran: OCEAN(a)-DOSE the #sirna therapy slashed lp(a) concentrations by as much as 100% in this phase ii study, paving the way for a larger trial. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term olpasiran in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' dramatic reductions in lp(a) with olpasiran: OCEAN(a)-DOSE the #sirna therapy slashed lp(a) concentrations by as much as 100% in this phase ii study, paving the way for a larger trial. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term olpasiran in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''immediate insertion of ecmo-cs in patients with #cardiogenicshock did not improve clinical outcomes compared with an early conservative strategy #aha22, ecmo-cs'''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term empa-kidney in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' (empa-kidney) (#empagliflozin) results were presented'''### Response: The sentiment polarity expressed regarding the given aspect term empa-kidney in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term BREXIT in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' #aha2022 exercise for the prevention of anthracycline-induced functional disability and cardiac dysfunction: the breast cancer randomized exercise intervention BREXIT study '''### Response: The sentiment polarity expressed regarding the given aspect term BREXIT in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term advor in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''acetazolamide & natriuresis in advor good or excellent natriuresis ~ una+ 280 mmol/l #acetazolamide allocation: n=186 or 80.5% vs placebo allocation: n=152 or 65.8% excretion of 115 mmol na+ (corresponding to 6.7 g salt) within 48 hr) #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term advor in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term acetazolamide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''acetazolamide & natriuresis in advor good or excellent natriuresis ~ una+ 280 mmol/l #acetazolamide allocation: n=186 or 80.5% vs placebo allocation: n=152 or 65.8% excretion of 115 mmol na+ (corresponding to 6.7 g salt) within 48 hr) #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term acetazolamide in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' dramatic reductions in lp(a) with olpasiran OCEAN(a)-DOSE the #sirna therapy slashed lp(a) concentrations by as much as 100% in this phase ii study, paving the way for a larger trial. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term olpasiran in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' dramatic reductions in lp(a) with olpasiran OCEAN(a)-DOSE the #sirna therapy slashed lp(a) concentrations by as much as 100% in this phase ii study, paving the way for a larger trial. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term olpasiran in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ironman in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ironmn : iv fe derisomaltose administration was associated with a lower risk of hospital admissions for #heartfailure and cv death #aha22 #jacc '''### Response: The sentiment polarity expressed regarding the given aspect term ironman in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term derisomaltose in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ironmn : iv fe derisomaltose administration was associated with a lower risk of hospital admissions for #heartfailure and cv death #aha22 #jacc '''### Response: The sentiment polarity expressed regarding the given aspect term derisomaltose in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term ironman in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#ironman for a broad range of patients with #heartfailure ( #lvef 45%) and fe deficiency, iv ferric derisomaltose was associated with a risk of admissions for hf and cv #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ironman in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 #transform-hf #dcp #prominent #ironman and more acc's full coverage of the latest science from american heart association's (aha) scientific sessions 2022 #jacc #heartfailure #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ironman in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 #transform-hf #dcp #prominent #ironman and more acc's full coverage of the latest science from american heart association's (aha) scientific sessions 2022 #jacc #heartfailure #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term ironman in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term dcp in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 #transform-hf #dcp #prominent #ironman and more acc's full coverage of the latest science from american heart association's (aha) scientific sessions 2022 #jacc #heartfailure #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term dcp in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term prominent in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 #transform-hf #dcp #prominent #ironman and more acc's full coverage of the latest science from american heart association's (aha) scientific sessions 2022 #jacc #heartfailure #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term prominent in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''transform-hf: torsemide no better than furosemide for hospitalized hf #heartfailure #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term torsemide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''transform-hf: torsemide no better than furosemide for hospitalized hf #heartfailure #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term torsemide in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term furosemide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''transform-hf: torsemide no better than furosemide for hospitalized hf #heartfailure #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term furosemide in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term CRISPR-ATTR in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''With CRISPR-ATTR ,apollo by day 28, all patients achieved #ttr reductions of at least 90% those in the nyha iii 0.7 mg/kg and #nyha i/ii 1.0 mg/kg cohorts achieved 94% and 92% ttr reductions, respectively, at 4 month the nyha i/ii 0.7 mg/kg group had achieved 93% ttr reductions at 6 month #aha22'''### Response: The sentiment polarity expressed regarding the given aspect term CRISPR-ATTR in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term apollo in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''With CRISPR-ATTR ,apollo by day 28, all patients achieved #ttr reductions of at least 90% those in the nyha iii 0.7 mg/kg and #nyha i/ii 1.0 mg/kg cohorts achieved 94% and 92% ttr reductions, respectively, at 4 month the nyha i/ii 0.7 mg/kg group had achieved 93% ttr reductions at 6 month #aha22'''### Response: The sentiment polarity expressed regarding the given aspect term apollo in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term CRISPR-ATTR in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''comparing the study findings to those of #apollo-b for the #sirna therapy patisiran , apollo-b reported a mean 87% reduction in #ttr so, so the effect of gene editing matches and actually exceeds the effect of #patisiran in #crispr/cas-9 gene editing #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term CRISPR-ATTR in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term apollo in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''comparing the study findings to those of #apollo-b for the #sirna therapy patisiran , apollo-b reported a mean 87% reduction in #ttr so, so the effect of gene editing matches and actually exceeds the effect of #patisiran in #crispr/cas-9 gene editing #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term apollo in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ironman in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ironman #aha22 impact of iv iron on hf hosp /cv randomized hfref pts to iv ferric derisomaltose or placebo primary endpoint 18% cv & recurrent hf but cv p=.23 covid sensitivity analysis p safe:no excess adverse events '''### Response: The sentiment polarity expressed regarding the given aspect term ironman in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term CRISPR-ATTR in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''novel CRISPR-ATTR -editing therapy shows promise for patients with transthyretin amyloid #cardiomyopathy #aha22 #heartfailure '''### Response: The sentiment polarity expressed regarding the given aspect term CRISPR-ATTR in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term ironman in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''ironman for a broad range of patients with #heartfailure ( #lvef 45%) and fe deficiency, iv ferric derisomaltose was associated with a risk of admissions for hf and cv #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term ironman in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term empa-kidney in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-2 empa-kidney respect-epa sport ocean(a) dose #rapco-rita and more acc's full coverage of the latest science from american heart association's (aha) 2022 #jacc #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term empa-kidney in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ocean(a)-dose in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-2 empa-kidney respect-epa sport ocean(a) dose #rapco-rita and more acc's full coverage of the latest science from american heart association's (aha) 2022 #jacc #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term ocean(a)-dose in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term respect-epa in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-2 empa-kidney respect-epa sport ocean(a) dose #rapco-rita and more acc's full coverage of the latest science from american heart association's (aha) 2022 #jacc #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term respect-epa in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term sport in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-2 empa-kidney respect-epa sport ocean(a) dose #rapco-rita and more acc's full coverage of the latest science from american heart association's (aha) 2022 #jacc #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term sport in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term rapco in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-2 empa-kidney respect-epa sport ocean(a) dose #rapco-rita and more acc's full coverage of the latest science from american heart association's (aha) 2022 #jacc #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term rapco in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term empagliflozin in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#originalresearch simpub #aha2022 #circaha22: the efficacy and safety of empagliflozin was similar in black and white patients with hf across the range of ef, with a suggestion of enhanced efficacy in black patient... '''### Response: The sentiment polarity expressed regarding the given aspect term empagliflozin in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term BREXIT in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#justpublished #aha22 #circaha22 exercise for the prevention of anthracycline-induced functional disability and cardiac dysfunction: the breast cancer randomized exercise intervention BREXIT study #ahajournals '''### Response: The sentiment polarity expressed regarding the given aspect term BREXIT in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term strong-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''strong-hf rapid uptitration of #gdmtworks after acute #heartfailure pays dividends the trial was stopped early due to a greater-than-expected benefit of high-intensity therapy after 1,078 patients (mean age 63 yrs; 39% ) were randomized #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term strong-hf in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term PROGRESSIVE-AF in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''PROGRESSIVE-AF first-line #ablation reduces #afib progression, boosts #qol patient-reported outcomes, including disease-specific and general #qol and symptom burden, also significantly favored an ablation-first strategy #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term PROGRESSIVE-AF in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term strong-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''strong-hf getting patients up to full doses of #gdmt within just 2 weeks of an acute #heartfailure hospitalization improves measures of congestion and clinical outcomes #aha22 just published in '''### Response: The sentiment polarity expressed regarding the given aspect term strong-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term BrigHTN in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''BrigHTN - phase 2 trial of baxdrostat for treatment-resistant hypertension this aldosterone synthase inhibitor, baxdrostat led to substantial reductions in sbp and dbp in patients with tx-resistant #hypertension #aha22 #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term BrigHTN in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term baxdrostat in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''BrigHTN - phase 2 trial of baxdrostat for treatment-resistant hypertension this aldosterone synthase inhibitor, baxdrostat led to substantial reductions in sbp and dbp in patients with tx-resistant #hypertension #aha22 #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term baxdrostat in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term PROGRESSIVE-AF in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''first-line ablation of PROGRESSIVE-AF trial was associated with lower risks of hospitalization (5.2% vs 16.8%; rr 0.31; 95% ci 0.14-0.66) and non-protocol ablations (17.5% vs 42.3%; rr 0.41; 95% ci 0.28-0.61) during the 3-year follow-up period #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term PROGRESSIVE-AF in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term best-cli in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-3 brightn spyral htn-on med early-af best-cli and more acc's full coverage of the latest science from american heart association's (aha) 2022 #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term best-cli in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term brightn in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-3 brightn spyral htn-on med early-af best-cli and more acc's full coverage of the latest science from american heart association's (aha) 2022 #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term brightn in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term early-af in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-3 brightn spyral htn-on med early-af best-cli and more acc's full coverage of the latest science from american heart association's (aha) 2022 #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term early-af in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term spyral htn-on med in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hot trials from #aha22 day-3 brightn spyral htn-on med early-af best-cli and more acc's full coverage of the latest science from american heart association's (aha) 2022 #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term spyral htn-on med in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' presents the outstanding results of the OCEAN(a)-DOSE trial. #aha2022 olpasiran, an sirna, led to a 95% reduction in lp(a) concentrations dosed 75 mg or higher every 12 weeks. '''### Response: The sentiment polarity expressed regarding the given aspect term OCEAN(a)-DOSE in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term olpasiran in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' presents the outstanding results of the OCEAN(a)-DOSE trial. #aha2022 olpasiran, an sirna, led to a 95% reduction in lp(a) concentrations dosed 75 mg or higher every 12 weeks. '''### Response: The sentiment polarity expressed regarding the given aspect term olpasiran in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term fourier-ole in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''thrilled to have presented the safety & efficacy analysis of fourier and fourier-ole as a late-breaker at #aha22! monotonic relationship btw lower ldl-c, <20mg/dl, and lower adverse cv events. huge thanks to dr. marc sabatine, and ! '''### Response: The sentiment polarity expressed regarding the given aspect term fourier-ole in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term fourier in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''thrilled to have presented the safety & efficacy analysis of fourier and fourier-ole as a late-breaker at #aha22! monotonic relationship btw lower ldl-c, <20mg/dl, and lower adverse cv events. huge thanks to dr. marc sabatine, and ! '''### Response: The sentiment polarity expressed regarding the given aspect term fourier in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''esc tv on the road at #aha22 our host is joined by: discussing transform_hf & focusing on ironman watch this space for full coverage #cardiotwitter #medtwitter #escyoung '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ironman in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''esc tv on the road at #aha22 our host is joined by: discussing transform_hf & focusing on ironman watch this space for full coverage #cardiotwitter #medtwitter #escyoung '''### Response: The sentiment polarity expressed regarding the given aspect term ironman in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term scored in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''had so much fun presenting the adjudicated results from the soloist-whf and scored trials! #aha2022 '''### Response: The sentiment polarity expressed regarding the given aspect term scored in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term soloist-whf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''had so much fun presenting the adjudicated results from the soloist-whf and scored trials! #aha2022 '''### Response: The sentiment polarity expressed regarding the given aspect term soloist-whf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term transform-hf in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' #aha22 late-breaking discussion drs and discuss the anticipated results of transform_hf no benefit of torsemide compared to furosemide in pts hospitalised with #hf! watch here #diuretics #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term transform-hf in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term torsemide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' #aha22 late-breaking discussion drs and discuss the anticipated results of transform_hf no benefit of torsemide compared to furosemide in pts hospitalised with #hf! watch here #diuretics #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term torsemide in the given tweet is negative
### Instruction: What sentiment polarity is expressed regarding the given aspect term furosemide in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' #aha22 late-breaking discussion drs and discuss the anticipated results of transform_hf no benefit of torsemide compared to furosemide in pts hospitalised with #hf! watch here #diuretics #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term furosemide in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term prominent in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''the prominent trial presented today at #aha2022 revealed that in patients with diabetes, mild to moderate hypertriglyceridemia and low hdl, pemafibrate did not lower rates of cv disease. '''### Response: The sentiment polarity expressed regarding the given aspect term prominent in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term pemafibrate in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''the prominent trial presented today at #aha2022 revealed that in patients with diabetes, mild to moderate hypertriglyceridemia and low hdl, pemafibrate did not lower rates of cv disease. '''### Response: The sentiment polarity expressed regarding the given aspect term pemafibrate in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#ecls as circulatory support in cs? results of ecmo-cs out! immediate #ecmo-cs feasible but no improved outcomes in rapidly deteriorating/severe cs (scai d-e) vs early conservative therapy allowing ecmo if worsening hemodynamics #foamcc #aha2022 '''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term prevent-hd in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''dr piazza presents prevent-hd results comparing prophylactic-dose rivaroxaban vs placebo in ambulatory patients with #covid19 infection. study terminated early due to low event rates with delta & omicron viral variants. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term prevent-hd in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term rivaroxaban in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''dr piazza presents prevent-hd results comparing prophylactic-dose rivaroxaban vs placebo in ambulatory patients with #covid19 infection. study terminated early due to low event rates with delta & omicron viral variants. #aha22 '''### Response: The sentiment polarity expressed regarding the given aspect term rivaroxaban in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ischemia-extend in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#aha22 extended follow-up of the ischemia-extend demonstrated that an initial invasive strategy vs. an initial conservative strategy resulted in: -no difference in all-cause mortality -lower risk of cardiovascular mortality -higher risk of non-cardiovascular mortality '''### Response: The sentiment polarity expressed regarding the given aspect term ischemia-extend in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term BRIGHT-4 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#aha22 bright4 trial or the come-back or bilalirudin data were presented'''### Response: The sentiment polarity expressed regarding the given aspect term BRIGHT-4 in the given tweet is neutal
### Instruction: What sentiment polarity is expressed regarding the given aspect term OPTION in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#aha22 the OPTION trial: indobufen+dapt is not inferior to aspirin+dapt after coronary drug-eluting stent implantation '''### Response: The sentiment polarity expressed regarding the given aspect term OPTION in the given tweet is positive
### Instruction: What sentiment polarity is expressed regarding the given aspect term PRECISE in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#aha22 the PRECISE trial: net clinical effectiveness of the precision strategy with a 70% reduction of the composite of death, non-fatal mi or catheterization without obstructive cad, compared to usual testing at 1 year '''### Response: The sentiment polarity expressed regarding the given aspect term PRECISE in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term RENAL-AF in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''apixaban for patients with atrial fibrillation on hemodialysis: a multicenter randomized controlled RENAL-AF trial '''### Response: The sentiment polarity expressed regarding the given aspect term RENAL-AF in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term apixaban in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''apixaban for patients with atrial fibrillation on hemodialysis: a multicenter randomized controlled RENAL-AF trial '''### Response: The sentiment polarity expressed regarding the given aspect term apixaban in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term CTS-AMI in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''join us for the #lbct session this am in main event i featuring several interesting trials including rapco CTS-AMI stress ecmo-cs #patogara, #joannechikwe #accearlycareer #accfit #accic #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term CTS-AMI in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term ecmo-cs in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''join us for the #lbct session this am in main event i featuring several interesting trials including rapco CTS-AMI stress ecmo-cs #patogara, #joannechikwe #accearlycareer #accfit #accic #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term ecmo-cs in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term rapco in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''join us for the #lbct session this am in main event i featuring several interesting trials including rapco CTS-AMI stress ecmo-cs #patogara, #joannechikwe #accearlycareer #accfit #accic #cardiotwitter '''### Response: The sentiment polarity expressed regarding the given aspect term rapco in the given tweet is neutral
### Instruction: What sentiment polarity is expressed regarding the given aspect term teer in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' tct @ aha case based discussions at #aha22 #aha2022 were a huge hit w/4 complex cases in a box w/ excellent discussion: rca cto in a pt w/ prior tavr w/ self expanding valve recalcitrant rca isr tavr in pure ar teer (ice+tee guided) in pt w/ sev smr & tr '''### Response: The sentiment polarity expressed regarding the given aspect term teer in the given tweet is neutral