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(A from Classen DC, Evans RS, Pestotnik SL, et al.
N Engl J Med.
1992;326:281-
286.
B from Steinberg JP, Braun BI, Hellinger WC, et al.
Ann
Surg.
• The primary insult from a burn is the wound itself.
The total burn size is typi-
cally less than 10% of total body surface area (TBSA) in 72% of cases.
Department of the Army, the U.S.
Department of Defense, or
the federal government.
The author is an employee of the U.S.
government, and this work was performed
as part of official duties.
487
238  Bites
Ellie J.
C.
Goldstein and Fredrick M.
DIAGNOSIS
• The diagnosis is made by the patient’s reported history of events.
• Plain radiographs should be obtained if there is a high likelihood of bony injury.
THERAPY
• Irrigate wounds with copious amounts of normal saline.
• Cautiously débride devitalized or necrotic tissue.
Follow rabies guidelines for details on management of bites that
carry a risk of rabies.
Culture
Aerobic and anaerobic cultures should be taken from infected wounds.
Irrigation
Copious amounts of normal saline should be used for irrigation.
Débridement
Devitalized or necrotic tissue should be cautiously débrided.
Wound Closure
Primary wound closure is not usually advocated.
For larger wounds, edges may be approximated with
adhesive strips in selected cases.
Immunizations
Provide tetanus and rabies immunization, if indicated.
Elevation
Elevation may be required if any edema is present.
Lack of elevation is a common cause of therapeutic
failure.
Reporting
Reporting the incident to a local health department may be required.
bid, two times a day; PO, orally; qid, four times a day; tid, three times a day.
• Provide t etanus and rabies immunization, as indicated.
TABLE 238-1  Management of Bite Wounds—cont’d
490
D  Zoonoses
239  Zoonoses
W.
Ian Lipkin
DEFINITION
• A zo onosis is an infectious disease of humans that originates in animals.
DIAGNOSIS
• The m ajority of zoonotic diseases are diagnosed using molecular methods.
Thus, treatment is primarily supportive.
In contrast, many
bacterial zo onoses can be treated with antibiotics.
PREVENTION
• Vaccines are established for only a minority of zoonotic diseases.
491
E  Protection of Travelers
240  Protection of Travelers
David O.
Ascertain which is best suited to the individual patient and
itinerary.
• E ducate on personal protection against arthropods.
TRAVELER’S DIARRHEA
• R ecommend food and water precautions.
493
241  Infections in Returning Travelers
David O.
• Is malaria possible?
If there is end-organ damage, initiate empirical therapy.
• Are there localizing findings?
Go to syndromic approach and differential diagnosis.
• Are there no localizing findings?
see Antiretroviral therapy (ART).
aeruginosa, 34t-36t
for pertussis, 339
for SFG rickettsioses, 258
for trachoma, 250
without P.
see Bronchoalveolar lavage (BAL).
see Banna virus (BAV).
Benzathine penicillin
for S.
see Catheter-associated urinary tract infection
(CA-UTI).
see Chronic fatigue syndrome (CFS).
see Cardiovascular implantable
electronic device (CIED) infections.
characteristics of, 362, 363t
other diseases associated with, 362
Clostridium tetani, 360
CMV.