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Paraphrase: A dog is in the sand that is blowing in the wind | A dog is in a sandy area with the sand that is being stirred up into the air and several plants are in the background |
Paraphrase: The black and white dog is running in a field | The black and white dog is running in a green yard |
Paraphrase: A woman wearing a blue shirt and high heels is standing on the sidewalk next to a man | A woman wearing a blue shirt and high heels is standing on the sidewalk next to the man |
Paraphrase: A woman wearing a blue shirt and high heels is standing on the sidewalk next to a man | A woman wearing a blue shirt and high heels is standing on the sidewalk next to a dog |
Paraphrase: A woman wearing a blue shirt and high heels is standing on the sidewalk next to a man | A man and a woman are standing on the curb |
Paraphrase: A dog is jumping high into the air in the country | A dog is jumping into the air in the country |
Paraphrase: A man on a green bike is performing tricks on a dirt ramp | The man on a green bike is performing tricks on the dirt ramp |
Paraphrase: A stuntman on a bike is in the air near a body of water | A person on a bike is in the air near a body of water |
Paraphrase: A young swimmer is sitting in a bathing suit and waiting for the next race | A young swimmer is standing in a bathing suit and waiting for the next race |
Paraphrase: A black dog and a white dog are wrestling on the floor | A black dog and a white dog are wrestling on the ground |
Paraphrase: A black dog and a tan dog are fighting | Two dogs are fighting |
Paraphrase: A black dog and a white dog are wrestling on the ground | Two dogs are fighting |
Paraphrase: A cluster of four brown dogs are playing in a field of brown grass | A group of four brown dogs are playing in a field of brown grass |
Paraphrase: Four dogs are playing in a area covered by grass | Four dogs are playing in a grassy area |
Paraphrase: A group of four brown dogs are playing in a field of brown grass | Four dogs are playing in a grassy area |
Paraphrase: The dog is having a nap in the park | The dog is having a rest in the park |
Paraphrase: A brown puppy is gnawing a metallic post that is stuck in the ground | A brown dog is gnawing a metallic post that is stuck in the ground |
Paraphrase: A brown puppy is biting a pole | A brown puppy is biting a stick |
Paraphrase: A brown puppy is gnawing a metallic post that is stuck in the ground | A brown puppy is biting a pole |
Paraphrase: A woman is petting a dog near a stone path | A man is petting a dog near a stone path |
Paraphrase: A woman is playing with a brown dog in a garden | A woman is playing with a brown dog on a garden path |
Paraphrase: Two men are walking through a river | Two men are walking through the water |
Paraphrase: Two men are standing in the ocean | Two men are standing in deep water |
Paraphrase: The rider dressed in orange is driving a motorcycle on one wheel | The orange rider is driving a motorcycle on one wheel |
Paraphrase: Tambourines are being played by a group of children | A group of children is playing tambourines |
Paraphrase: A group of children in a church basement is playing maracas and tambourines | A group of children in a building's basement is playing maracas and tambourines |
Paraphrase: A group of children in a building's basement is playing maracas and tambourines | A group of children is playing tambourines |
Paraphrase: A group of children in a church basement is playing guitars and tambourines | A group of children is playing tambourines |
Paraphrase: A brown dog is running in the snow | The brown dog is running in the snow |
Paraphrase: A brown dog is running in the snow | A black dog is running in the snow |
Paraphrase: An elderly man is sitting on a bench | An old person is sitting on a bench |
Paraphrase: An elderly woman is sitting on a bench and is wearing a gray jacket and black pants | The woman is sitting on a bench and is wearing a gray jacket and black pants |
Paraphrase: A dog is fetching a piece of wood out of very clear water | A dog is fetching a stick out of very clear water |
Paraphrase: The girl in a blue coverall is painting | The girl in the blue coverall is painting |
Paraphrase: A golden retriever is running | A dog is running |
Paraphrase: A yellow dog is running down a sandy path | A yellow dog is running down a path covered by sand |
Paraphrase: A yellow dog is running up a sandy path | A yellow dog is running down a sandy path |
Paraphrase: A yellow dog is running down a sandy path | A dog is running |
Paraphrase: A dog is standing on one leg and is waiting for a soccer ball | A dog is standing on one leg and is waiting for a ball |
Paraphrase: Two men are seated on a camel and another camel is in the foreground | Two people are seated on a camel and another camel is in the foreground |
Paraphrase: Two people are seated near a camel and another camel is in the foreground | Two people are seated on a camel and another camel is in the foreground |
Paraphrase: Two people are seated on a camel and another camel is in the foreground | People are riding two camels at the beach |
Paraphrase: A man is wearing a blue shirt and walking barefoot on a tennis court | A person is wearing a blue shirt and walking barefoot on a tennis court |
Paraphrase: A barefoot man in pajamas is looking toward the sky and is walking on the tennis court | A barefoot man in pajamas is looking toward the sky and is standing on the tennis court |
Paraphrase: The man is standing in the water at the base of a waterfall | A man is standing in the water at the base of a waterfall |
Paraphrase: A brown and white dog is running through the river | A brown and white dog is running through the water |
Paraphrase: A shirtless man is leading a horse that is pulling a carriage | A shirtless man is leading a carriage that is being pulled by a horse |
Paraphrase: A shirtless man is escorting a horse that is pulling a carriage along a paved road | A shirtless man is escorting a horse that is pulling a carriage along a dirty road |
Paraphrase: A shirtless man is escorting a horse that is pulling a carriage along a road | A shirtless man is leading a horse that is pulling a carriage |
Paraphrase: A little girl and a woman wearing a yellow shirt are getting splashed by a city fountain | A little girl and a woman wearing a yellow shirt are getting splashed near a fountain |
Paraphrase: A little boy and a woman wearing a yellow shirt are getting splashed by a city fountain | A little girl and a woman wearing a yellow shirt are getting splashed by a city fountain |
Paraphrase: A girl in an orange shirt and clown makeup is walking in a park and others are looking on | A girl in an orange shirt and clown makeup is standing in a park and others are looking on |
Paraphrase: A woman is showing a puppy to an infant | A woman is showing a small dog to an infant |
Paraphrase: A black and white dog with a large branch is running in the field | A black and white dog with a large branch is running in the grass |
Paraphrase: A black and white dog is carrying a big stick on the green grass | A black and white dog is carrying a huge stick on the green grass |
Paraphrase: A black and white dog with a large branch is running in the grass | A black and white dog is carrying a huge stick on the green grass |
Paraphrase: A black and white dog with a large branch is standing in the field | A black and white dog is carrying a huge stick on the green grass |
Paraphrase: A boy wearing a striped shirt is running barefoot on the sandy hill | A kid wearing a striped shirt is running barefoot on the sandy hill |
Paraphrase: A boy is running on the beach | A boy is running through the sand |
Paraphrase: A motorcycle racer is riding a red and black bike | The motorcycle racer is riding a red and black bike |
Paraphrase: A woman is firing at target practice | A woman is shooting at target practice |
Paraphrase: A woman is wearing ear protection and is firing a gun at an indoor shooting range | The woman is wearing ear protection and is firing a gun at an indoor shooting range |
Paraphrase: A woman is wearing ear protection and is firing a gun at an outdoor shooting range | A woman is shooting at target practice |
Paraphrase: A woman is wearing ear protection and is firing a gun at an indoor shooting range | A woman is shooting at target practice |
Paraphrase: Two young boys are looking up at the camera and one is sticking out his tongue | Two kids are looking up at the camera and one is sticking out his tongue |
Paraphrase: The little boy is sticking his tongue out for the camera and another boy is looking on | A little boy is sticking his tongue out for the camera and another boy is looking on |
Paraphrase: The large dog is walking outside and is carrying a colorful toy in its mouth | The large dog is walking outside and is holding a colorful toy in its mouth |
Paraphrase: A dog is standing on concrete and is holding a blue ball | The large dog is walking outside and is carrying a colorful toy in its mouth |
Paraphrase: It has recently been shown that Craf is essential for Kras G12D-induced NSCLC. | It has recently become evident that Craf is essential for the onset of Kras-driven non-small cell lung cancer. |
Paraphrase: Several lines of evidence suggest that the known principal RB pathway lesions in human tumors act in a mutual exclusive manner. | In individual human tumor specimens, these principal components of the pathway—RB-CDK4/6-p16INK4A—are reported to be targeted in a mutually exclusive manner. |
Paraphrase: Furthermore, a very recent study demonstrated the mechanism that specifies myeloid expression of miR-223 and proposed a unique “minicircuitry” comprised of miR-223 and transcription factors, NFI-A and CAAT enhancer-binding protein α (C/EBPα) | miR-223 regulates granulopoiesis by a feedback mechanism and is modulated competitively by the transcription factors nuclear factor I/A (NFI-A) and CCAAT/enhancer binding protein-α (C/EBPα). |
Paraphrase: In myelopoiesis, miR-223 has been shown to regulate granulocyte development in both humans and mice. | As shown previously, miR-223 is highly conserved, and its myeloid-specific expression is also well characterized in both human and mouse |
Paraphrase: Unique segments of homologous sequences in RIP1 and RIP3 (RIP homotypic interaction motifs, RHIMs) were shown to mediate their interaction | RIP1 was reported to interact with RIP3. |
Paraphrase: This form of necrosis, also termed necroptosis, requires the activity of receptor-interacting protein kinase 1 (RIP1) and its related kinase, RIP3 | Moreover, other reports have also shown that necroptosis could be induced via modulating RIP1 and RIP3. |
Paraphrase: Furthermore, ablation of both Erk1 and Erk2 impaired tumor development, whereas inactivation of either one alone had no effect. | Only concomitant ablation of ERK1 and ERK2 impairs tumor growth. |
Paraphrase: Importantly, the role of ERK phosphorylation in Kras-driven NSCLCs has been recently highlighted by the demonstration that ERK activity is essential for Kras-driven lung tumorigenesis. | As mentioned above, high ERK activity is crucial for the development of Kras-driven NSCLCs. |
Paraphrase: Lung tumour formation in mice by oncogenic KRAS requires CRaf, but not BRaf. | The oncogenic activity of mutant Kras appears dependent on functional Craf but not on Braf. |
Paraphrase: BAF53 and β-actin subunits have been implicated in mammalian SWI/SNF-regulated binding to the chromatin/nuclear matrix. | In addition, Arp4-related BAF53 and β-actin are components of the human SWI/SNF complex and could play a role in its signal-regulated binding to the chromatin/nuclear matrix |
Paraphrase: The mammalian Arp, BAF53 (BRG-associated factor), and β-actin were initially found as components of the mammalian SWI/SNF-like BAF chromatin-remodeling complex. | In addition, Arp4-related BAF53 and β-actin are components of the human SWI/SNF complex and could play a role in its signal-regulated binding to the chromatin/nuclear matrix |
Paraphrase: In eukaryotic cells, small G-proteins are critically regulated by Guanine nucleotide Exchange Factors (GEFs) and GTPase Activating Proteins (GAPs). | Eukaryotic small G-proteins are often controlled through the balancing actions of GAPs and GEFs. |
Paraphrase: These findings were identical to the pattern of expression seen in human acute lymphoid and myeloid leukemias with MLL rearrangements. | These genes are consistently expressed in leukemias with MLL rearrangements. |
Paraphrase: A few studies have reported the control of APC/C by genotoxic stress in mammalian cells, Ionizing radiation was shown to activate the APC/C to degrade cyclin D1, which triggers an immediate p53-independent G1 arrest. | In fact, genotoxic stresses such as ionizing radiation have been demonstrated to trigger rapid proteolysis of cyclin D1, leading to p53-independent G1 arrest. |
Paraphrase: For the analysis of expression at different stages of differentiation, data were obtained for 43 mouse samples in StemBase , originating from 16 studies with Affymetrix MOE430A microarray chips, as used in an Oct4 expression profiling study covering murine ESCs, embryonal carcinoma cell lines, and several early differentiated lineages. | We investigated the patterns of expression of the Oct4-associated data set in cells at different stages of differentiation, including embryonic carcinoma, embryonic stem cells, embryoid bodies, and various differentiated cell types, on the basis of transcriptomics data. |
Paraphrase: Expression of an activated form of Ras proteins can induce senescence in some primary fibroblasts. | The senescent state has been observed to be inducible in certain cultured cells in response to high level expression of genes such as the activated ras oncogene. |
Paraphrase: The up-regulation of miR-146a was also detected in cervical cancer tissues. | The expression of miR-146a has been found to be up-regulated in cervical cancer. |