Datasets:

surrey-nlp

/

PLOD-filtered

like 0

Follow

University of Surrey NLP Group 63

[ "Incidence", "rate", "ratios", "(", "IRRs", ")", "were", "estimated", "using", "Poisson", "regression", "." ]

[ 8, 8, 8, 13, 12, 13, 3, 16, 16, 12, 8, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "brief", "our", "overall", "study", "included", "key", "informant", "interviews", "with", "treatment", "providers", "and", "public", "health", "officials", "(", "n", "=", "13", ")", ",", "15", "focus", "group", "discussions", "(", "FGD", ")", "with", "TB", "patients", "(", "n", "=", "61", ")", "and", "non", "-", "patients", "(", "n", "=", "31", ")", ",", "and", "a", "survey", "of", "community", "health", "volunteers", "(", "n", "=", "101", ")", "." ]

[ 1, 8, 11, 0, 8, 16, 0, 8, 8, 1, 8, 8, 5, 0, 8, 8, 13, 8, 13, 9, 13, 13, 9, 8, 8, 8, 13, 12, 13, 1, 12, 8, 13, 8, 13, 9, 13, 5, 8, 8, 8, 13, 8, 13, 9, 13, 13, 5, 6, 8, 1, 8, 8, 8, 13, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "brief", ",", "we", "obtained", "similar", "results", "from", "animal", "models", "fitted", "to", "the", "untransformed", "parturition", "date", "data", ",", "but", "these", "models", "performed", "relatively", "poorly", "(", "skewed", "residuals", "and", "poor", "Markov", "Chain", "Monte", "Carlo", "[", "MCMC", "]", "mixing", ")", ",", "which", "may", "impair", "the", "reliability", "of", "estimates", "." ]

[ 1, 8, 13, 11, 16, 0, 8, 1, 8, 8, 16, 1, 6, 0, 8, 8, 8, 13, 5, 6, 8, 16, 2, 2, 13, 0, 8, 5, 0, 12, 12, 12, 12, 17, 12, 17, 8, 13, 13, 11, 3, 16, 6, 8, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "0.891", "is", "the", "conversion", "factor", "between", "EBW", "and", "SBW", "[", "11", "]", ".", "EBF=", "17.76207", "+", "4.68142×FT+0.01945×HCW+0.81855×MS−0.06754×REA(4", ")", "EBF=", "14.08796", "+", "4.7135×FT+0.01316×HCW+0.90855×MS(5", ")", "EBW=1.316×HCW+32.39(6", ")", "AFSBWCT", "=", "EBW+14.26×(28−EBF)0.891(7", ")", "Where", "EBF", "is", "empty", "body", "fat", ",", "%", ";", "FT", "is", "fat", "thickness", ",", "cm", ";", "HCW", "is", "hot", "carcass", "weight", ",", "kg", ";", "MS", "is", "marbling", "score", "(", "2", "=", "practically", "devoid", ",", "3", "=", "traces", ",", "4", "=", "slight", ",", "5", "=", "small", ",", "6", "=", "modest", ",", "7", "=", "Moderate", ",", "8", "=", "slightly", "abundant", ",", "and", "9", "=", "moderately", "abundant", ")", ";", "REA", "is", "ribeye", "area", ",", "cm2", ";", "EBW", "is", "empty", "body", "weight", ",", "kg", ";", "and", "AFSBW", "is", "adjusted", "final", "shrunk", "body", "weight", "at", "28", "%", "empty", "body", "fat", ",", "kg", "." ]

[ 6, 9, 3, 6, 8, 8, 1, 12, 5, 12, 13, 9, 13, 13, 12, 9, 9, 9, 13, 12, 9, 9, 9, 13, 12, 13, 12, 15, 12, 13, 14, 12, 3, 0, 8, 8, 13, 8, 13, 12, 3, 8, 8, 13, 8, 13, 12, 3, 0, 8, 8, 13, 8, 13, 12, 3, 8, 8, 13, 9, 15, 2, 0, 13, 9, 15, 8, 13, 9, 15, 0, 13, 9, 15, 0, 13, 9, 15, 0, 13, 9, 15, 0, 13, 9, 15, 2, 0, 13, 5, 9, 15, 2, 0, 13, 13, 12, 3, 8, 8, 13, 8, 13, 12, 3, 0, 8, 8, 13, 8, 13, 5, 12, 3, 16, 0, 16, 8, 8, 1, 9, 8, 0, 8, 8, 13, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "present", "study", "aimed", "to", "investigate", "the", "possible", "protective", "role", "of", "candesartan", "(", "CAND", ")", "and", "sodium", "thiosulfate", "(", "STS", ")", "in", "ameliorating", "ethylene", "glycol", "(", "EG", ")", "induced", "nephrolithiasis", "." ]

[ 6, 0, 8, 16, 10, 16, 6, 0, 0, 8, 1, 8, 13, 12, 13, 5, 8, 8, 13, 12, 13, 1, 16, 8, 8, 13, 12, 13, 16, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 3, 4, 0, 1, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0 ]

[ "The", "whole", "time", "-", "courses", "of", "lesioned", "and", "sham", "groups", "were", "compared", "using", "binomial", "generalized", "linear", "mixed", "models", "(", "GLMM", ")", "[", "22", "]", ",", "with", "lesioned", "/", "sham", "(", "'", "LESION", "'", ";", "set", "to", "true", "in", "lesioned", "animals", "post", "-", "surgery", ",", "false", "otherwise", ")", "and", "operated", "/", "unoperated", "(", "'", "OPERATED", "'", ";", "set", "to", "false", "before", "surgery", ",", "true", "after", "surgery", ")", "as", "fixed", "factors", ",", "animal", "as", "a", "random", "factor", "and", "time", "as", "a", "continuous", "covariate", "." ]

[ 6, 0, 8, 0, 8, 1, 16, 5, 8, 8, 3, 16, 16, 0, 0, 0, 16, 8, 13, 12, 13, 13, 9, 13, 13, 1, 16, 15, 8, 13, 13, 12, 13, 13, 16, 1, 0, 1, 16, 8, 0, 0, 8, 13, 0, 2, 13, 5, 16, 15, 0, 13, 13, 16, 13, 13, 16, 1, 0, 1, 8, 13, 0, 1, 8, 13, 1, 16, 8, 13, 8, 1, 6, 0, 8, 5, 8, 1, 6, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Legend", ":", "Precentral", "gyrus", "(", "PreCG", ")", ",", "hippocampus", "(", "HIP", ")", ",", "parahippocampal", "gyrus", "(", "PHG", ")", "." ]

[ 8, 13, 0, 8, 13, 12, 13, 13, 8, 13, 12, 13, 13, 0, 8, 13, 12, 13, 13 ]

[ 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 1, 0, 0, 3, 4, 0, 1, 0, 0 ]

[ "To", "investigate", "the", "correlation", "between", "geographic", "filling", "delays", "in", "the", "choriocapillaris", "using", "indocyanine", "green", "angiography", "(", "ICGA", ")", "images", "and", "dilated", "vortex", "veins", "in", "central", "serous", "chorioretinopathy", "(", "CSC", ")", "." ]

[ 10, 16, 6, 8, 1, 0, 8, 8, 1, 6, 8, 16, 0, 0, 8, 13, 12, 13, 8, 5, 16, 8, 8, 1, 0, 0, 8, 13, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0 ]

[ "Golgi", "staining", "revealed", "a", "24", "%", "reduction", "in", "dendritic", "length", "(", "Fig", "5H", ",", "5I", "and", "5J", ")", "and", "a", "30", "%", "loss", "of", "spine", "density", "(", "Fig", "5", "K", ")", "in", "the", "field", "CA1", "of", "CA1", "hippocampus", "(", "CA1", ")", "of", "APPPS1", "mice", "at", "12", "months", "compared", "with", "age", "-", "matched", "WT", "littermates", "as", "well", "as", "a", "more", "severe", "46", "%", "reduction", "in", "dendritic", "length", "and", "a", "43", "%", "loss", "of", "spine", "density", "in", "APPPS1", "–", "Adamts13−/−", "mice", "compared", "with", "age", "-", "matched", "WT", "littermates", "." ]

[ 8, 8, 16, 6, 9, 8, 8, 1, 0, 8, 13, 8, 9, 13, 8, 5, 8, 13, 5, 6, 9, 8, 8, 1, 8, 8, 13, 8, 9, 8, 13, 1, 6, 8, 12, 1, 12, 8, 13, 12, 13, 1, 12, 8, 1, 9, 8, 16, 1, 8, 13, 16, 12, 8, 1, 2, 1, 6, 2, 0, 9, 8, 8, 1, 0, 8, 5, 6, 9, 8, 8, 1, 8, 8, 1, 12, 13, 12, 8, 16, 1, 8, 13, 16, 12, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 1, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0 ]

[ "BMI", "=", "body", "mass", "index", ";", "HDL", "=", "high", "-", "density", "lipoprotein", ";", "FPIS", "=", "first", "-", "phase", "insulin", "secretion", ";", "SPIS", "=", "second", "-", "phase", "insulin", "secretion", ";", "IR", "=", "insulin", "resistance", ";", "GE", "=", "glucose", "effectiveness", "." ]

[ 12, 16, 8, 8, 8, 13, 12, 16, 0, 13, 8, 8, 13, 12, 16, 0, 13, 8, 8, 8, 13, 12, 16, 0, 13, 8, 8, 8, 13, 12, 16, 8, 8, 13, 12, 16, 8, 8, 13 ]

[ 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0 ]

[ "Data", "are", "shown", "as", "mean", "±", "standard", "deviation", "(", "SD", ")", "(", "n", "=", "6", ")", ",", "*", "p", "<", "0.05", ",", "*", "*", "p", "<", "0.01", ",", "*", "*", "*", "p", "<", "0.001", ".", "(", "B", ")", "Immunofluorescent", "images", "showing", "green", "labeling", "at", "the", "cell", "-", "cell", "borders", "of", "CLD5", ",", "OLCN", ",", "ZO-1", ",", "and", "ZO-2", "in", "mBECs", ",", "rBECs", ",", "and", "pBECs", "cultured", "in", "mono-", "or", "co", "-", "culture", "with", "astrocytes", "." ]

[ 8, 3, 16, 1, 8, 8, 0, 8, 13, 12, 13, 13, 8, 15, 9, 13, 13, 13, 8, 1, 9, 13, 13, 13, 8, 1, 9, 13, 13, 13, 13, 8, 1, 9, 13, 13, 8, 13, 0, 8, 16, 0, 8, 1, 6, 8, 0, 8, 8, 1, 12, 13, 12, 13, 12, 13, 5, 12, 1, 12, 13, 12, 13, 5, 12, 16, 1, 0, 5, 0, 0, 0, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 1, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "A1c", ",", "hemoglobin", "A1c" ]

[ 12, 13, 8, 8 ]

[ 1, 0, 3, 4 ]

[ "Activity", "counts", "(", "AC", ")", "from", "three", "sensing", "axes", "are", "integrated", "to", "vector", "magnitude", "(", "VM", "):", "VM=(Axis1)2+(Axis2)2+(Axis3)2" ]

[ 8, 8, 13, 12, 13, 1, 9, 16, 8, 3, 16, 1, 8, 8, 13, 8, 13, 8 ]

[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "One", "mutant", "line", "(", "NF9014", ")", "carried", "a", "Tos17", "insertion", "in", "the", "third", "exon", "of", "the", "Xb15", "gene", "(", "Figure", "5A", ")", ".", "This", "insertion", "resulted", "in", "a", "lack", "of", "expression", "of", "the", "full", "-", "length", "Xb15", "mRNA", "compared", "to", "the", "wild", "type", "Nipponbare", "plants", "when", "tested", "with", "appropriate", "primers", "by", "reverse", "transcription", "-", "PCR", "(", "RT-PCR", ")", "(", "Figure", "5B", ")", ".", "18S", "ribosomal", "RNA", "(", "18SrRNA", ")", "was", "used", "as", "an", "internal", "control", "." ]

[ 9, 0, 8, 13, 9, 13, 16, 6, 8, 8, 1, 6, 0, 8, 1, 6, 8, 8, 13, 12, 9, 13, 13, 6, 8, 16, 1, 6, 8, 1, 8, 1, 6, 0, 13, 8, 8, 8, 16, 1, 6, 0, 8, 12, 8, 14, 16, 1, 0, 8, 1, 0, 8, 13, 8, 13, 12, 13, 13, 12, 9, 13, 13, 8, 0, 8, 13, 12, 13, 3, 16, 1, 6, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "As", "an", "example", ",", "the", "importance", "of", "tumor", "cell", "proliferation", "in", "primary", "tumor", "tissue", ",", "by", "mitotic", "count", "(", "MC", ")", "and", "Ki-67", "expression", "has", "been", "extensively", "studied", ",", "but", "information", "about", "such", "markers", "in", "tumor", "metastases", "is", "very", "limited", "[", "10–18", "]", "." ]

[ 1, 6, 8, 13, 6, 8, 1, 8, 8, 8, 1, 0, 8, 8, 13, 1, 0, 8, 13, 12, 13, 5, 8, 8, 3, 3, 2, 16, 13, 5, 8, 1, 0, 8, 1, 8, 8, 3, 2, 0, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "However", ",", "a", "role", "for", "Spry2", "in", "enhancing", "epidermal", "growth", "factor", "(", "extracellular", "EGF)-induced", "signal", "-", "regulated", "kinase", "1/2", "(", "ERK1/2", ")", "activation", "by", "preventing", "c", "-", "Cbl", "–", "mediated", "degradation", "of", "EGF", "receptor", "has", "also", "been", "described", "[", "14", "]", "." ]

[ 2, 13, 6, 8, 1, 12, 1, 16, 0, 8, 8, 13, 0, 12, 8, 13, 16, 8, 9, 13, 12, 13, 8, 1, 16, 8, 13, 8, 13, 16, 8, 1, 12, 8, 3, 2, 3, 16, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 3, 4, 4, 0, 3, 1, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "implemented", "a", "bootstrap", "procedure", "to", "construct", "90", "%", "uncertainty", "intervals", "(", "UIs", ")", "for", "the", "U5MR", "and", "ARR", "to", "complement", "the", "UN", "estimates", "." ]

[ 11, 16, 6, 8, 8, 10, 16, 9, 8, 8, 8, 13, 12, 13, 1, 6, 12, 5, 12, 10, 16, 6, 12, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 1, 0, 1, 0, 0, 0, 1, 0, 0 ]

[ "This", "resulting", "matrix", "was", "used", "as", "input", "for", "three", "different", "prediction", "models", ":", "support", "vector", "machine", "(", "SVM", ")", "with", "linear", "kernel", ",", "generalized", "linear", "model", "net", "(", "glmnet", ")", ",", "and", "PLS", ".", "Three", "algorithms", "were", "used", "in", "order", "to", "support", "the", "interpretation", "of", "the", "results", ",", "assuming", "that", "metabolites", "appearing", "as", "important", "in", "different", "algorithms", "are", "biologically", "relevant", "." ]

[ 6, 16, 8, 3, 16, 1, 8, 1, 9, 0, 8, 8, 13, 16, 8, 8, 13, 12, 13, 1, 0, 8, 13, 16, 0, 8, 8, 13, 12, 13, 13, 5, 12, 13, 9, 8, 3, 16, 1, 8, 10, 16, 6, 8, 1, 6, 8, 13, 16, 14, 8, 16, 1, 0, 1, 0, 8, 3, 2, 0, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "AIS", ",", "Abbreviated", "Injury", "Scale", ";", "CT", ",", "computed", "tomography", ";", "ED", ",", "emergency", "department", ";", "GCS", ",", "Glasgow", "Coma", "Score", "." ]

[ 12, 13, 0, 12, 8, 13, 12, 13, 16, 8, 13, 12, 13, 8, 8, 13, 12, 13, 12, 12, 8, 13 ]

[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0 ]

[ "The", "Mendelian", "randomization", "pleiotropy", "residual", "sum", "and", "outlier", "(", "MR", ")", "global", "test", "and", "-PRESSOMV", "extension", "thereof", "[", "47", "]", "were", "used", "to", "facilitate", "identification", "and", "removal", "of", "outlier", "variants", "in", "order", "to", "correct", "potential", "directional", "horizontal", "pleiotropy", "and", "resolve", "detected", "heterogeneity", "." ]

[ 6, 0, 8, 8, 0, 8, 5, 0, 13, 12, 13, 0, 8, 5, 12, 8, 2, 17, 17, 17, 3, 16, 10, 16, 8, 5, 8, 1, 0, 8, 1, 8, 10, 16, 0, 0, 0, 8, 5, 16, 16, 8, 13 ]

[ 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Furthermore", ",", "many", "soluble", "chaperone", "proteins", "that", "function", "within", "the", "ER", "—", "as", "well", "as", "proteins", "too", "large", "to", "enter", "classic", "coat", "protein", "complex", "II", "(", "COPII", ")", "ER", "-", "exit", "vesicles", ",", "such", "as", "fibrillar", "collagens", "—", "start", "with", "tripeptides", "that", "can", "not", "bind", "to", "Surf4", "/", "Erv29p", "." ]

[ 2, 13, 0, 0, 8, 8, 11, 16, 1, 6, 12, 13, 1, 2, 1, 8, 2, 0, 1, 16, 0, 8, 8, 8, 9, 13, 12, 13, 12, 13, 8, 8, 13, 0, 1, 8, 8, 13, 16, 1, 8, 11, 3, 10, 16, 1, 12, 15, 12, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0 ]

[ "Many", "conflicting", "reports", "about", "the", "involvement", "of", "serum", "amyloid", "P", "component", "(", "SAP", ")", "in", "amyloid", "diseases", "have", "been", "presented", "over", "the", "years", ";", "SAP", "is", "known", "to", "be", "a", "universal", "component", "of", "amyloid", "aggregates", "but", "it", "has", "been", "suggested", "that", "it", "can", "both", "induce", "and", "suppress", "amyloid", "formation", "." ]

[ 0, 0, 8, 1, 6, 8, 1, 8, 8, 8, 8, 13, 12, 13, 1, 8, 8, 3, 3, 16, 1, 6, 8, 13, 12, 3, 16, 10, 3, 6, 0, 8, 1, 8, 8, 5, 11, 3, 3, 16, 14, 11, 3, 5, 16, 5, 16, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "A", "DDB2", "depletion", "by", "transfection", "with", "specific", "siRNA", "(", "Figure", "S2B", ")", "prevented", "this", "UV", "-", "induced", "DDB1", "translocation", "to", "chromatin", "and", ",", "accordingly", ",", "suppressed", "the", "ubiquitylation", "of", "XPC", "(", "Figure", "S2C", ")", ".", "As", "a", "consequence", "of", "this", "diminished", "ubiquitylation", ",", "the", "relocation", "of", "XPC", "to", "internucleosomal", "sites", ",", "but", "not", "to", "insoluble", "core", "particles", ",", "was", "reduced", "(", "Figure", "3A", ")", ".", "This", "and", "follow", "-", "up", "findings", "involving", "the", "role", "of", "protein", "ubiquitylation", "are", "confirmed", "by", "a", "quantitative", "assessment", "of", "immunoblots", "over", "3–5", "independent", "experiments", "(", "Figure", "3B", ")", ".", "In", "siRNA", "-", "mediated", "depletion", "experiments", ",", "DDB2", "was", "down", "regulated", "incompletely", "to", "∼10", "%", "of", "control", "cells", "(", "Figure", "S2B", ")", ".", "However", ",", "a", "stronger", "aversion", "of", "XPC", "for", "internucleosomal", "DNA", "was", "observed", "in", "XP", "-", "E", "cells", "displaying", "no", "residual", "UV", "activity", "(", "Figure", "S2D", ")", ".", "Finally", ",", "Figure", "S2E", "shows", "that", "the", "normal", "abundance", "of", "XPC", "at", "solubilizable", "internucleosomal", "sites", "was", "restored", "upon", "complementation", "of", "DDB2", "-", "depleted", "cells", "with", "DDB2", "fused", "to", "green", "-", "fluorescent", "protein", "(", "DDB2", "-", "-DDBGFP", ")", "." ]

[ 6, 12, 8, 1, 8, 1, 0, 8, 13, 8, 8, 13, 16, 6, 12, 13, 16, 8, 8, 1, 8, 5, 13, 2, 13, 16, 6, 8, 1, 8, 13, 8, 8, 13, 13, 1, 6, 8, 1, 6, 16, 8, 13, 6, 8, 1, 8, 1, 0, 8, 13, 5, 10, 1, 0, 8, 8, 13, 3, 16, 13, 8, 9, 13, 13, 11, 5, 16, 13, 1, 8, 16, 6, 8, 1, 8, 8, 3, 16, 1, 6, 0, 8, 1, 8, 1, 9, 0, 8, 13, 8, 9, 13, 13, 1, 8, 13, 16, 8, 8, 13, 12, 3, 2, 16, 2, 1, 9, 8, 1, 8, 8, 13, 8, 8, 13, 13, 2, 13, 6, 0, 8, 1, 8, 1, 0, 8, 3, 16, 1, 12, 13, 12, 8, 16, 6, 0, 12, 8, 13, 8, 8, 13, 13, 2, 13, 8, 8, 16, 14, 6, 0, 8, 1, 8, 1, 0, 0, 8, 3, 16, 14, 8, 1, 12, 13, 16, 8, 1, 12, 16, 1, 0, 13, 0, 8, 13, 12, 13, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 0, 0, 1, 0, 0 ]

[ "Compared", "to", "non", "-", "diabetic", "individuals", ",", "those", "with", "diabetes", "seem", "to", "be", "more", "likely", "to", "experience", "atrioventricular", "(", "AV", ")", "delay", "or", "block", "[", "27", "]", "." ]

[ 16, 10, 0, 0, 0, 8, 13, 11, 1, 8, 16, 10, 3, 2, 0, 10, 16, 0, 13, 12, 13, 8, 5, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Although", "the", "benefit", "of", "physical", "activity", "is", "recognized", ",", "studies", "still", "have", "shown", "that", "physical", "activity", "is", "related", "to", "sudden", "cardiac", "death", "(", "SCD", ")", ",", "even", "in", "a", "healthy", "population", "[", "8", "]", ",", "and", "this", "problem", "worries", "people", ",", "especially", "patients", "with", "CAD", "." ]

[ 14, 6, 8, 1, 0, 8, 3, 16, 13, 8, 2, 3, 16, 14, 0, 8, 3, 16, 1, 0, 0, 8, 13, 12, 13, 13, 2, 1, 6, 0, 8, 13, 9, 13, 13, 5, 6, 8, 16, 8, 13, 2, 8, 1, 12, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0 ]

[ "Neurofibromatosis", "type", "1", "(", "NF1", ")", "is", "the", "most", "common", "inherited", "cancer", "predisposition", "syndrome", "." ]

[ 8, 8, 9, 13, 12, 13, 3, 6, 2, 0, 16, 8, 8, 8, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Health", "status", "covariates", "included", "hypertension", "(", "systolic", "/", "diastolic", "≥", "140/90", "mmHg", "or", "use", "of", "antihypertensive", "medication", ")", ",", "prevalent", "diabetes", "mellitus", "(", "determined", "by", "fasting", "glucose", "≥", "7.0", "mmol", "/", "l", ",", "a", "2", "-", "hour", "postload", "glucose", "≥", "11.1", "mmol", "/", "l", ",", "reported", "doctor", "-", "diagnosed", "diabetes", ",", "or", "use", "of", "diabetes", "medication", ")", ",", "self", "-", "reported", "use", "of", "medication", "for", "cardiovascular", "disease", ",", "mental", "health", "(", "30", "-", "item", "General", "Health", "Questionnaire", ")", "[", "25", "]", ",", "and", "HES", "linkage", "data", "on", "coronary", "heart", "disease", "(", "CHD", ";", "ICD", "codes", ":", "I20", "–", "I25", ")", ",", "stroke", "(", "ICD", "codes", ":", "I60", "–", "I64", ")", ",", "and", "chronic", "obstructive", "pulmonary", "disease", "(", "ICD", "codes", ":", "J41", "–", "J44", ")", "." ]

[ 12, 8, 8, 16, 8, 13, 0, 15, 0, 13, 9, 8, 5, 8, 1, 0, 8, 13, 13, 0, 8, 8, 13, 16, 1, 16, 8, 13, 9, 8, 15, 8, 13, 6, 9, 13, 8, 8, 8, 13, 9, 8, 15, 8, 13, 16, 8, 13, 16, 8, 13, 5, 8, 1, 8, 8, 13, 13, 8, 13, 16, 8, 1, 8, 1, 0, 8, 13, 0, 8, 13, 9, 13, 8, 12, 12, 12, 13, 13, 9, 13, 13, 5, 12, 8, 8, 1, 0, 8, 8, 13, 12, 13, 12, 8, 13, 9, 13, 9, 13, 13, 8, 13, 12, 8, 13, 9, 13, 9, 13, 13, 5, 0, 0, 0, 8, 13, 12, 8, 13, 9, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "To", "examine", "how", "ciliopathy", "protein", "complexes", "might", "function", "together", ",", "we", "have", "analyzed", "double", "mutants", "of", "an", "allele", "of", "the", "Meckel", "syndrome", "(", "MKS", ")", "complex", "protein", "MKS1", "and", "the", "BBSome", "protein", "BBS4", ".", "We", "find", "that", "Mks1", ";", "Bbs4", "double", "mutant", "mouse", "embryos", "exhibit", "exacerbated", "defects", "in", "Hedgehog", "(", "Hh", ")", "dependent", "patterning", "compared", "to", "either", "single", "mutant", ",", "and", "die", "by", "E14.5", "." ]

[ 10, 16, 14, 8, 8, 8, 3, 16, 2, 13, 11, 3, 16, 0, 8, 1, 6, 8, 1, 6, 12, 8, 13, 12, 13, 8, 8, 12, 5, 6, 12, 8, 12, 13, 11, 16, 14, 12, 13, 12, 0, 8, 8, 8, 16, 16, 8, 1, 12, 13, 12, 13, 0, 8, 16, 1, 6, 0, 8, 13, 5, 16, 1, 9, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "MSM", ",", "men", "who", "have", "sex", "with", "men", "." ]

[ 12, 13, 8, 11, 16, 8, 1, 8, 13 ]

[ 1, 0, 3, 4, 4, 4, 4, 4, 0 ]

[ "We", "used", "decision", "-", "curve", "analysis", "(", "DCA", ")", "to", "describe", "and", "compare", "the", "clinical", "implications", "of", "using", "each", "risk", "model", "." ]

[ 11, 16, 8, 13, 8, 8, 13, 12, 13, 10, 16, 5, 16, 6, 0, 8, 1, 16, 6, 8, 8, 13 ]

[ 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "An", "elastic", "net", "(", "EN", ")", "algorithm", "[", "40", "]", "was", "applied", "for", "estimating", "GAs", "using", "the", "ELISA", "data", "." ]

[ 6, 0, 8, 13, 12, 13, 8, 17, 17, 17, 3, 16, 1, 16, 12, 16, 6, 12, 8, 13 ]

[ 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "Isothermal", "titration", "calorimetry", "(", "ITC", ")", "was", "used", "to", "determine", "the", "relative", "enthalpies", "of", "binding", "of", "the", "series", "of", "F", "-", "substituted", "phenolates", "to", "the", "pKSI", "D40N", "enzyme", "." ]

[ 0, 8, 8, 13, 12, 13, 3, 16, 1, 16, 6, 0, 8, 1, 16, 1, 6, 8, 1, 8, 13, 16, 8, 1, 6, 12, 8, 8, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0 ]

[ "Violence", "and", "other", "traumas", "increase", "the", "risk", "of", "multiple", "mental", "health", "problems", "including", "symptoms", "of", "posttraumatic", "stress", "(", "PTS", ")", ",", "depression", ",", "and", "anxiety", "." ]

[ 8, 5, 0, 8, 16, 6, 8, 1, 0, 0, 8, 8, 16, 8, 1, 0, 8, 13, 12, 13, 13, 8, 13, 5, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "spite", "of", "repeated", "outbreaks", ",", "including", "the", "devastating", "2014–2016", "West", "Africa", "epidemic", ",", "there", "are", "no", "approved", "antiviral", "therapeutics", "against", "Ebola", "virus", "(", "EBOV", ")", "." ]

[ 1, 8, 1, 16, 8, 13, 16, 6, 0, 9, 12, 12, 8, 13, 11, 16, 6, 16, 0, 8, 1, 12, 8, 13, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0 ]

[ "For", "the", "RNA", "sequencing", "(", "RNA-seq", ")", "experiments", ",", "3", "biological", "replicates", "per", "tissue", "were", "prepared", "." ]

[ 1, 6, 8, 8, 13, 12, 13, 8, 13, 9, 0, 8, 1, 8, 3, 16, 13 ]

[ 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "As", "we", "did", "not", "observe", "differences", "on", "hepatic", "inflammation", "in", "vivo", ",", "we", "next", "investigated", "whether", "bone", "marrow", "-", "derived", "macrophages", "(", "BMDM", ")", "of", "myeloid", "DLL4", "-", "deficient", "mice", "are", "less", "susceptible", "for", "inflammation", "." ]

[ 14, 11, 3, 10, 16, 8, 1, 0, 8, 1, 0, 13, 11, 2, 16, 14, 8, 8, 13, 16, 8, 13, 12, 13, 1, 12, 12, 13, 0, 8, 3, 2, 0, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Given", "the", "apparent", "enhancement", "of", "mineralized", "nodule", "formation", "by", "Sam68−/−", "bone", "marrow", "stromal", "cells", "ex", "vivo", "and", "the", "phenotype", "observed", "with", "short", "hairpin", "RNA", "(", "shRNA)-treated", "C3H10T1/2", ",", "we", "stained", "sections", "of", "bone", "from", "4-", "and", "12", "-", "month", "-", "old", "mice", "for", "evidence", "of", "changes", "in", "marrow", "adiposity", "." ]

[ 16, 6, 0, 8, 1, 0, 8, 8, 1, 12, 8, 8, 0, 8, 2, 2, 5, 6, 8, 16, 1, 0, 8, 8, 13, 12, 8, 13, 11, 16, 8, 1, 8, 1, 9, 5, 9, 13, 8, 13, 0, 8, 1, 8, 1, 8, 1, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Using", "a", "combination", "of", "structure", "equation", "modeling", "and", "in", "vivo", "models", "of", "MIP", ",", "Conroy", "and", "colleagues", "showed", "that", "monocytic", "infiltration", "contributes", "to", "complement", "activation", "and", "subsequent", "dysregulation", "of", "angiogenic", "factors", ",", "such", "as", "soluble", "Endoglin", "(", "sEng", ")", ",", "that", "are", "essential", "for", "placental", "angiogenesis", "and", "vascular", "remodeling", "[", "16", "]", "." ]

[ 16, 6, 8, 1, 8, 8, 8, 5, 1, 0, 8, 1, 12, 13, 12, 5, 8, 16, 11, 0, 8, 16, 1, 8, 8, 5, 0, 8, 1, 0, 8, 13, 0, 1, 0, 12, 13, 12, 13, 13, 11, 3, 0, 1, 0, 8, 5, 0, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Our", "study", "area", "(", "Muang", "District", ",", "Kamphaeng", "Phet", "Province", "[", "KPP", "]", ",", "north", "-", "central", "Thailand", "[", "19", "]", ")", "is", ",", "by", "Thai", "standards", ",", "relatively", "sparsely", "populated", "with", "233,033", "residents", "in", "63,500", "houses", "in", "an", "area", "encompassing", "1,962", "km2", "." ]

[ 11, 8, 8, 13, 12, 12, 13, 12, 12, 12, 13, 12, 13, 13, 8, 13, 0, 12, 13, 9, 13, 13, 3, 13, 1, 0, 8, 13, 2, 2, 0, 1, 9, 8, 1, 9, 8, 1, 6, 8, 16, 9, 9, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "quantified", "this", "uncertainty", "by", "generating", "1,000", "samples", "of", "the", "coefficients", "through", "Monte", "Carlo", "simulations", ",", "assuming", "a", "normal", "distribution", "for", "the", "estimated", "coefficients", ",", "and", "then", "generating", "results", "for", "each", "of", "the", "five", "GCMs", ".", "We", "reported", "the", "results", "as", "point", "estimates", ",", "using", "the", "average", "across", "climate", "models", "(", "GCM", "ensemble", ")", "obtained", "by", "the", "estimated", "coefficients", ",", "and", "as", "empirical", "confidence", "intervals", "(", "eCIs", ")", ",", "defined", "as", "the", "2.5th", "and", "97.5th", "percentiles", "of", "the", "empirical", "distribution", "across", "coefficients", "samples", "and", "GCMs", ".", "These", "empirical", "95", "%", "eCI", "account", "for", "both", "sources", "of", "uncertainty", "." ]

[ 11, 16, 6, 8, 1, 16, 9, 8, 1, 6, 8, 1, 12, 12, 8, 13, 16, 6, 0, 8, 1, 6, 16, 8, 13, 5, 2, 16, 8, 1, 11, 1, 6, 9, 12, 13, 11, 16, 6, 8, 1, 8, 8, 13, 16, 6, 8, 1, 8, 8, 13, 12, 8, 13, 16, 1, 6, 16, 8, 13, 5, 1, 0, 8, 8, 13, 12, 13, 13, 16, 1, 6, 0, 5, 9, 8, 1, 6, 0, 8, 1, 8, 8, 5, 12, 13, 6, 0, 9, 8, 12, 16, 1, 6, 8, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Mouse", "D122", "Lewis", "lung", "carcinoma", "(", "LLC", ")", "and", "mouse", "Ret", "melanoma", "cells", "[", "33", "]", "(", "both", "syngeneic", "to", "C57BL/6J", "mice", ")", ",", "and", "human", "PC14", "-", "PE6", "adenocarcinoma", "cells", "were", "cultured", "in", "complete", "media", "(", "RPMI", "1640", "supplemented", "with", "10", "%", "fetal", "bovine", "serum", "and", "1", "%", "penicillin", "/", "streptomycin", ";", "Biological", "Industries", ")", "." ]

[ 0, 12, 12, 8, 8, 13, 12, 13, 5, 8, 12, 8, 8, 17, 17, 17, 13, 11, 0, 1, 8, 8, 13, 13, 5, 0, 8, 13, 8, 8, 8, 3, 16, 1, 0, 8, 13, 12, 9, 16, 1, 9, 8, 0, 0, 8, 5, 9, 8, 8, 15, 8, 13, 12, 12, 13, 13 ]

[ 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Particularly", ",", "sphingosine-1", "-", "phosphate", "(", "S1P", ")", ",", "a", "final", "product", "of", "sphingolipid", "metabolism", ",", "is", "a", "potent", "bioactive", "lipid", "involved", "in", "the", "regulation", "of", "various", "cellular", "processes", ",", "including", "cell", "proliferation", ",", "cell", "migration", ",", "actin", "cytoskeletal", "reorganization", "and", "cell", "adhesion", "." ]

[ 2, 13, 8, 13, 8, 13, 12, 13, 13, 6, 0, 8, 1, 8, 8, 13, 3, 6, 0, 0, 8, 16, 1, 6, 8, 1, 0, 0, 8, 13, 16, 8, 8, 13, 8, 8, 13, 8, 0, 8, 5, 8, 8, 13 ]

[ 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "homogenates", "were", "used", "for", "the", "estimation", "of", "superoxide", "dismutase", "(", "SOD", ")", ",", "total", "antioxidant", "capacity", "(", "MDA", ")", ",", "MCP1", ",", "TNF", "-", "α", ",", "HSP70", ",", "Bax", ",", "PLCγ", "and", "ERK1/2protein", "expression", "by", "enzyme", "-", "linked", "immunosorbent", "assay", "(", "ELISA", ")", "(", "R&D", "Sys", ".", ",", "USA", ")", "according", "to", "the", "manufacturer", "’s", "protocol", "." ]

[ 6, 8, 3, 16, 1, 6, 8, 1, 8, 8, 13, 12, 13, 13, 0, 0, 8, 13, 12, 13, 13, 12, 13, 12, 13, 13, 13, 12, 13, 12, 13, 12, 5, 8, 8, 1, 8, 13, 16, 8, 8, 13, 12, 13, 13, 12, 12, 13, 13, 12, 13, 16, 1, 6, 8, 10, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Epilepsy", "is", "more", "than", "seizures", "and", "includes", "a", "high", "risk", "of", "comorbidities", "and", "psychological", "disorders", ",", "leading", "to", "poor", "quality", "of", "life", "(", "QOL", ")", ".", "Earlier", "studies", "have", "showed", "a", "sedentary", "lifestyle", "in", "people", "with", "epilepsy", "(", "PWE", ")", ",", "which", "could", "contribute", "to", "poorer", "health", "and", "psychological", "problems", "." ]

[ 8, 3, 0, 1, 8, 5, 16, 6, 0, 8, 1, 8, 5, 0, 8, 13, 16, 1, 0, 8, 1, 8, 13, 12, 13, 13, 0, 8, 3, 16, 6, 0, 8, 1, 8, 1, 8, 13, 12, 13, 13, 11, 3, 16, 1, 0, 8, 5, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "To", "evaluate", "kidney", "damage", ",", "blood", "urea", "nitrogen", "(", "BUN", ")", "and", "creatinine", "were", "measured", "(", "Fig", "5", ")", "." ]

[ 10, 16, 8, 8, 13, 8, 8, 8, 13, 12, 13, 5, 8, 3, 16, 13, 9, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "observed", "that", "HIV", "gene", "expression", "was", "reduced", "5", "-", "fold", "in", "cells", "treated", "with", "HR73", "as", "measured", "by", "GFP", "expression", "(", "HIV", "GFP", "in", "Figure", "6D", ")", ".", "In", "contrast", ",", "GFP", "expression", "in", "cells", "infected", "with", "an", "HIV", "-", "based", "lentiviral", "vector", "expressing", "GFP", "from", "the", "elongation", "factor", "1α", "(", "EF-1α", ")", "promoter", "was", "not", "affected", "by", "HR73", "treatment", "(", "HIV", "[", "EF-1α", "]", "in", "Figure", "6D", ")", ".", "These", "data", "confirm", "the", "selectivity", "of", "HR73", "for", "HIV", "transcription", "and", "demonstrate", "that", "other", "steps", "in", "the", "viral", "life", "cycle", ",", "including", "reverse", "transcription", ",", "nuclear", "import", ",", "and", "integration", ",", "remain", "unaffected", "by", "HR73", "." ]

[ 11, 16, 14, 12, 8, 8, 3, 16, 2, 13, 2, 1, 8, 16, 1, 12, 14, 16, 1, 12, 8, 13, 12, 12, 1, 8, 9, 13, 13, 1, 8, 13, 12, 8, 1, 8, 16, 1, 6, 12, 13, 16, 0, 8, 16, 12, 1, 6, 8, 8, 9, 13, 12, 13, 8, 3, 10, 16, 1, 12, 8, 13, 12, 17, 12, 17, 1, 8, 9, 13, 13, 6, 8, 16, 6, 8, 1, 12, 1, 12, 8, 5, 16, 14, 0, 8, 1, 6, 0, 8, 8, 13, 16, 0, 8, 13, 0, 8, 13, 5, 8, 13, 16, 0, 1, 12, 13 ]

[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "primary", "outcome", "was", "moderate", "anaemia", "(", "haemoglobin", "[", "Hb", "]", "<", "8", "g", "/", "dl", ")", ";", "major", "secondary", "outcomes", "were", "health", "care", "utilisation", ",", "severe", "anaemia", ",", "and", "mortality", "." ]

[ 6, 0, 8, 3, 0, 8, 13, 8, 17, 12, 17, 15, 9, 8, 15, 8, 13, 13, 0, 0, 8, 3, 8, 8, 8, 13, 0, 8, 13, 5, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "the", "late", "phase", "(", "BD", "+", "5h", ")", ",", "brain", "death", "was", "associated", "with", "further", "increased", "gene", "expression", "for", "IL-10", "and", "IL-8", ",", "with", "no", "changes", "in", "IL-1β", ",", "IL-6", ",", "TNF", "α", "and", "pro", "-", "inflammatory", "-IL-6", "/", "IL-10", "mRNA", "content", "in", "total", "lung", "homogenates", "." ]

[ 1, 6, 0, 8, 13, 12, 15, 9, 13, 13, 8, 8, 3, 16, 1, 2, 16, 8, 8, 1, 12, 5, 12, 13, 1, 6, 8, 1, 12, 13, 12, 13, 12, 13, 5, 0, 0, 0, 12, 15, 12, 8, 8, 1, 0, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Pyruvate", "Kinase", "(", "PK", ")", "activity", "was", "measured", "by", "a", "coupled", "enzymatic", "assay", "NADH", "/", "lactate", "dehydrogenase", "(", "LDH", ")", "[", "44", "]", "." ]

[ 8, 8, 13, 12, 13, 8, 3, 16, 1, 6, 16, 0, 8, 8, 15, 8, 8, 13, 8, 13, 13, 9, 13, 13 ]

[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "DSBs", "processed", "along", "the", "ZMM", "pathway", "form", "double", "Holliday", "junctions", "(", "dHJs", ")", "that", "are", "asymmetrically", "resolved", "to", "produce", "COs", "[", "13,15", "]", "(", "Fig", "1A", ")", ".", "ZMM", "-", "promoted", "COs", "are", "distributed", "throughout", "the", "genome", "by", "a", "phenomenon", "called", "genetic", "interference", "[", "16", "]", "." ]

[ 12, 16, 1, 6, 8, 8, 16, 0, 12, 8, 13, 12, 13, 11, 3, 2, 16, 10, 16, 12, 13, 17, 13, 13, 8, 9, 13, 13, 8, 13, 16, 12, 3, 16, 1, 6, 8, 1, 6, 8, 16, 0, 8, 13, 9, 13, 13 ]

[ 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "eukaryotic", "cells", ",", "small", "G", "-", "proteins", "are", "critically", "regulated", "by", "Guanine", "nucleotide", "Exchange", "Factors", "(", "GEFs", ")", "and", "GTPase", "Activating", "Proteins", "(", "GAPs", ")", "[", "20],[21", "]", "." ]

[ 1, 0, 8, 13, 0, 8, 13, 8, 3, 2, 16, 1, 12, 8, 12, 8, 13, 12, 13, 5, 12, 16, 8, 13, 12, 13, 17, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]

[ "MS", ",", "multiple", "sclerosis", ";", "NAWM", ",", "normal", "-", "appearing", "white", "matter", "." ]

[ 12, 13, 0, 8, 13, 12, 13, 0, 13, 16, 0, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 4, 4, 0 ]

[ "BHC", ",", "benzenehexacarboxylic", "acid", ";", "dNTP", ",", "deoxynucleotide", "triphosphate", ";", "rNTP", ",", "ribonucleoside", "triphosphate", "." ]

[ 12, 13, 8, 8, 13, 12, 13, 8, 8, 13, 8, 13, 8, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0 ]

[ "Multiple", "sclerosis", "(", "MS", ")", ",", "an", "autoimmune", "disease", ",", "is", "characterized", "by", "damage", "and", "loss", "of", "neuronal", "cells", "caused", "by", "infiltration", "of", "auto", "-", "reactive", "immune", "cells", "into", "the", "central", "nervous", "system", "." ]

[ 0, 8, 13, 12, 13, 13, 6, 0, 8, 13, 3, 16, 1, 8, 5, 8, 1, 0, 8, 16, 1, 8, 1, 0, 0, 0, 0, 8, 1, 6, 0, 0, 8, 13 ]

[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "vertebrate", "Sortilin", "-", "related", "CNS", "expressed", "1–3", "(", "SorCS1", "-", "3", ")", "proteins", "are", "sorting", "receptors", "belonging", "to", "the", "vacuolar", "protein", "sorting", "10", "(", "VPS10P", ")", "family", "receptors", "that", "have", "emerged", "as", "major", "regulators", "of", "intracellular", "protein", "trafficking", "[", "18,19", "]", "." ]

[ 6, 0, 8, 13, 16, 8, 16, 9, 13, 12, 13, 9, 13, 8, 3, 8, 8, 16, 1, 6, 0, 8, 8, 9, 13, 12, 13, 8, 8, 11, 3, 16, 1, 0, 8, 1, 0, 8, 8, 13, 9, 13, 13 ]

[ 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Statistical", "analysis", "was", "performed", "on", "these", "acoustic", "features", "between", "ZF", "and", "OF", "by", "one", "-", "way", "ANOVA", ".", "For", "the", "analysis", "of", "the", "sequence", "feature", "of", "songs", "(", "motif", "and", "repetition", "rates", "in", "a", "song", ")", ",", "a", "syllable", "similarity", "matrix", "(", "SSM", ")", "analysis", "was", "performed", "following", "a", "previously", "reported", "method", "[", "30", "]", "(", "S1", "Fig", ")", "." ]

[ 0, 8, 3, 16, 1, 6, 0, 8, 1, 12, 5, 12, 1, 9, 13, 8, 8, 13, 1, 6, 8, 1, 6, 8, 8, 1, 8, 13, 8, 5, 8, 8, 1, 6, 8, 13, 13, 6, 8, 8, 8, 13, 12, 13, 8, 3, 16, 16, 6, 2, 16, 8, 17, 17, 17, 13, 12, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "While", "whiplash", "-", "associated", "disorder", "(", "WAD", ")", "has", "attracted", "considerable", "scientific", "attention", "[", "2–4", "]", ",", "other", "minor", "traffic", "-", "related", "injuries", "have", "been", "less", "well", "studied", "." ]

[ 14, 8, 13, 16, 8, 13, 12, 13, 3, 16, 0, 0, 8, 13, 9, 13, 13, 0, 0, 8, 13, 16, 8, 3, 3, 2, 2, 16, 13 ]

[ 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Transcript", "abundance", "estimation", ",", "fragments", "per", "kilobase", "of", "exon", "per", "million", "fragments", "mapped", "(", "FPKM", ")", "calculations", ",", "and", "normalization", "was", "done", "using", "Cufflinks", "[", "70–73", "]", ",", "a", "package", "of", "tools", "for", "transcriptome", "assembly", "and", "differential", "expression", "analysis", "of", "RNA", "-", "Seq", "data", "." ]

[ 0, 8, 8, 13, 8, 1, 8, 1, 8, 1, 9, 8, 16, 13, 12, 13, 8, 13, 5, 8, 3, 16, 16, 12, 9, 9, 13, 13, 6, 8, 1, 8, 1, 8, 8, 5, 0, 8, 8, 1, 12, 13, 12, 8, 13 ]

[ 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Strengths", "include", ":", "(", "i", ")", "Post", "-", "Post", "outlier", "outcomes", "in", "zero", "heterogeneity", "highlight", "combinability", "of", "the", "studies", ";", "(", "ii", ")", "consistency", "of", "significant", "associations", "strengthens", "the", "evidence", "for", "increased", "ADP", "associations", "with", "DN", ";", "(", "iii", ")", "predictive", "potential", "of", "ADP", "is", "bolstered", "by", "significant", "AUC", "under", "non", "-", "heterogeneous", "conditionsand", "(", "iv", ")", "all", "comparisons", "were", "deemed", "robust", "underpinning", "the", "stability", "of", "our", "findings", "." ]

[ 8, 16, 13, 13, 17, 13, 0, 0, 12, 0, 8, 1, 9, 8, 16, 8, 1, 6, 8, 13, 13, 17, 13, 8, 1, 0, 8, 16, 6, 8, 1, 16, 12, 8, 1, 12, 13, 13, 17, 13, 0, 8, 1, 12, 3, 16, 1, 0, 8, 1, 0, 0, 0, 8, 13, 17, 13, 6, 8, 3, 16, 0, 16, 6, 8, 1, 11, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 3, 4, 1, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Active", "Case", "Finding", "for", "Tuberculosis", "through", "TOUCH", "Agents", "in", "Selected", "High", "TB", "Burden", "Wards", "of", "Kolkata", ",", "India", ":", "A", "Mixed", "Methods", "Study", "on", "Outcomes", "and", "Implementation", "Challenges", "." ]

[ 0, 8, 8, 1, 8, 1, 8, 8, 1, 16, 0, 12, 8, 8, 1, 12, 13, 12, 13, 6, 0, 8, 8, 1, 8, 5, 8, 8, 13 ]

[ 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "To", "analyze", "the", "immunomodulatory", "potential", ",", "human", "peripheral", "blood", "mononuclear", "cells", "(", "PBMCs", ")", "obtained", "from", "healthy", "blood", "donor", "candidates", "were", "cultured", "in", "RPMI-1640", "medium", "in", "a", "96", "-", "well", "plate", "and", "incubated", "for", "24h", "with", "5", "-", "N", "-", "methylmaytenine", "(", "12.5", "μM", "and", "25", "μM", ")", "or", "stepharine", "(", "28.48", "μM", "and", "57.0", "μM", ")", ".", "After", "the", "incubation", ",", "the", "supernatants", "were", "collected", "for", "cytokine", "assays", "." ]

[ 10, 16, 6, 0, 8, 13, 0, 0, 8, 0, 8, 13, 12, 13, 16, 1, 0, 8, 8, 8, 3, 16, 1, 12, 8, 1, 6, 9, 13, 8, 8, 5, 16, 1, 9, 1, 9, 13, 8, 13, 8, 13, 9, 12, 5, 9, 12, 13, 5, 8, 13, 9, 12, 5, 9, 12, 13, 13, 1, 6, 8, 13, 6, 8, 3, 16, 1, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "It", "is", "estimated", "that", "each", "year", "in", "the", "United", "States", ",", "over", "4.8", "million", "patients", "present", "to", "emergency", "departments", "(", "EDs", ")", "after", "sustaining", "blunt", "head", "trauma", "." ]

[ 11, 3, 16, 14, 6, 8, 1, 6, 12, 12, 13, 1, 9, 9, 8, 16, 1, 8, 8, 13, 12, 13, 1, 16, 0, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Therefore", ",", "we", "have", "chosen", "to", "study", "a", "5", "-", "megabase", "(", "Mb", ")", "genomic", "region", "in", "which", "the", "LD", "structure", "has", "been", "characterized", "in", "detail", "in", "relation", "to", "an", "anxiety", "quantitative", "trait", "locus", "(", "QTL", ")", "in", "mouse", "[", "12", "]", "." ]

[ 2, 13, 11, 3, 16, 1, 16, 6, 9, 13, 8, 13, 12, 13, 0, 8, 1, 11, 6, 12, 8, 3, 3, 16, 1, 8, 1, 8, 1, 6, 8, 0, 8, 8, 13, 12, 13, 1, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Behavioral", "pain", "scale", "(", "BPS", ")", ",", "and", "critical", "care", "pain", "observation", "tool", "(", "CPOT", ")", "provide", "acceptable", "levels", "of", "validity", "and", "reliability", ",", "and", "are", "recommended", "for", "nonverbal", "pain", "screening", "." ]

[ 0, 8, 8, 13, 12, 13, 13, 5, 0, 8, 8, 8, 8, 13, 12, 13, 16, 0, 8, 1, 8, 5, 8, 13, 5, 3, 16, 1, 0, 8, 8, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "As", "an", "adaptation", "to", "nutrient", "limitations", "in", "terrestrial", "ecosystems", ",", "most", "plants", "form", "Arbuscular", "Mycorrhiza", "(", "AM", ")", ",", "which", "is", "a", "symbiotic", "relationship", "between", "phosphate", "-", "delivering", "fungi", "and", "plant", "roots", "that", "dates", "back", "to", "the", "earliest", "land", "plants", "." ]

[ 1, 6, 8, 1, 8, 8, 1, 0, 8, 13, 0, 8, 16, 12, 8, 13, 12, 13, 13, 11, 3, 6, 0, 8, 1, 8, 13, 16, 8, 5, 8, 8, 11, 16, 2, 1, 6, 0, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "(", "A", ")", "Duration", "of", "loss", "of", "righting", "reflex", "(", "LRR", ")", "was", "assessed", "immediately", "following", "the", "sham", "or", "TBI", "procedure", ".", "(", "B", ")", "Composite", "neurological", "severity", "score", "(", "NSS", ")", "was", "assessed", "at", "1", "h", "and", "at", "1", ",", "2", "and", "7", "d", "post", "-", "rTBI", ".", "(", "C", ")", "Motor", "performance", "was", "assessed", "on", "an", "accelerating", "rotarod", "at", "1", ",", "2", ",", "and", "7", "d", "post", "-", "rTBI", ".", "The", "graph", "depicts", "fall", "latency", "in", "seconds", "at", "baseline", "before", "rTBI", "and", "at", "three", "post", "-", "rTBI", "time", "points", ".", "(", "D", ")", "Thigmotaxis", "was", "quantified", "at", "1", "and", "6", "d", "post", "-", "rTBI", "and", "is", "represented", "as", "thigmotaxis", "index", ".", "(", "E", ")", "Aggressive", "behavior", "was", "assessed", "with", "the", "RIT", "at", "the", "5th", "(", "RIT", "#", "1", ")", "and", "6th", "(", "RIT", "#", "2", ")", "week", "following", "initiation", "of", "AAS", "treatment", "(", "pre", "-", "rTBI", ")", "as", "well", "as", "at", "5", "d", "(", "RIT", "#", "3", ")", "post", "-", "rTBI", ".", "Graphs", "represent", "latency", "to", "initiate", "fighting", "by", "the", "resident", "mouse", "." ]

[ 13, 17, 13, 8, 1, 8, 1, 16, 8, 13, 12, 13, 3, 16, 2, 16, 6, 8, 5, 12, 8, 13, 13, 17, 13, 0, 0, 8, 8, 13, 12, 13, 3, 16, 1, 9, 8, 5, 1, 9, 13, 9, 5, 9, 8, 0, 0, 12, 13, 13, 17, 13, 8, 8, 3, 16, 1, 6, 16, 8, 1, 9, 13, 9, 13, 5, 9, 8, 0, 0, 12, 13, 6, 8, 16, 8, 8, 1, 8, 1, 8, 1, 12, 5, 1, 9, 0, 0, 12, 8, 8, 13, 13, 17, 13, 8, 3, 16, 1, 9, 5, 9, 8, 0, 0, 12, 5, 3, 16, 1, 8, 8, 13, 13, 17, 13, 0, 8, 3, 16, 1, 6, 12, 1, 6, 0, 13, 12, 8, 9, 13, 5, 0, 13, 12, 8, 9, 13, 8, 16, 8, 1, 12, 8, 13, 0, 0, 12, 13, 1, 2, 1, 1, 9, 8, 13, 12, 8, 9, 13, 0, 0, 12, 13, 8, 16, 8, 10, 16, 8, 1, 6, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Stunting", ",", "anemia", "and", "inflammation", "are", "frequently", "observed", "in", "children", "with", "end", "-", "stage", "renal", "disease", "(", "ESRD", ")", "." ]

[ 8, 13, 8, 5, 8, 3, 2, 16, 1, 8, 1, 8, 13, 8, 0, 8, 13, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0 ]

[ "SVR", "is", "defined", "as", "persistent", "undetectable", "HCV", "RNA", "12", "weeks", "after", "the", "end", "of", "therapy", "(", "FU12", ")", ",", "assessed", "with", "a", "highly", "sensitive", "assay", "with", "a", "lower", "limit", "of", "detection", "(", "LOD", ")", "of", "≤", "15", "UI", "/", "ml", "[", "9", "]", "." ]

[ 12, 3, 16, 1, 0, 0, 12, 8, 9, 8, 1, 6, 8, 1, 8, 13, 12, 13, 13, 16, 1, 6, 2, 0, 8, 1, 6, 0, 8, 1, 8, 13, 12, 13, 1, 13, 9, 8, 15, 8, 13, 9, 13, 13 ]

[ 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "13del", "expressing", "HCs", "in", "the", "mid", "to", "lower", "HZ", ",", "but", "not", "wt", "cells", ",", "were", "also", "found", "to", "express", "cyclin", "D1", ",", "a", "marker", "for", "the", "G1", "phase", "(", "Figure", "4C", ",", "Figure", "S3B", ")", ".", "Proliferating", "cell", "nuclear", "antigen", "(", "PCNA", ")", ",", "a", "marker", "for", "proliferating", "cells", ",", "was", "also", "expressed", "specifically", "by", "cells", "of", "the", "13del", "HZ", ",", "but", "not", "wt", "(", "Figure", "4D", ")", ".", "Together", ",", "these", "data", "suggest", "that", "in", "13del", "mice", ",", "hypertrophic", "differentiation", "was", "initiated", ",", "but", "HCs", "in", "the", "mid", "to", "lower", "HZ", "re", "-", "entered", "the", "cell", "cycle", "." ]

[ 6, 12, 16, 12, 1, 6, 0, 10, 0, 12, 13, 5, 10, 12, 8, 13, 3, 2, 16, 10, 16, 8, 12, 13, 6, 8, 1, 6, 12, 8, 13, 12, 9, 13, 12, 9, 13, 13, 16, 8, 0, 8, 13, 12, 13, 13, 6, 8, 1, 16, 8, 13, 3, 2, 16, 2, 1, 8, 1, 6, 12, 12, 13, 5, 10, 12, 13, 12, 9, 13, 13, 2, 13, 6, 8, 16, 14, 1, 12, 8, 13, 0, 8, 3, 16, 13, 5, 12, 1, 6, 0, 10, 0, 12, 16, 16, 16, 6, 8, 8, 13 ]

[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "also", "uncover", "that", "upon", "gp130", "signaling", ",", "Klf6", "activates", "the", "nuclear", "import", "factor", "importin", "-", "α5", "(", "Impα5", ")", ",", "a", "key", "controller", "of", "trafficking", "into", "the", "nucleus", "in", "the", "CNS", ".", "Notably", ",", "inactivation", "of", "Impα5", "recapitulates", "the", "features", "of", "silencing", "Klf6", ",", "whereas", "Impα5", "expression", "can", "partially", "rescue", "differentiation", "in", "Klf6", "-", "deficient", "oligodendrocyte", "progenitors", "." ]

[ 11, 2, 16, 14, 14, 8, 8, 13, 12, 16, 6, 0, 8, 8, 8, 13, 8, 13, 12, 13, 13, 6, 0, 8, 1, 8, 1, 6, 8, 1, 6, 12, 13, 2, 13, 8, 1, 12, 16, 6, 8, 1, 16, 12, 13, 14, 12, 8, 3, 2, 16, 8, 1, 12, 13, 0, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "CHC", ",", "cuticular", "hydrocarbon", ";", "GLMM", ",", "generalized", "linear", "mixed", "model", ";", "Vg", ",", "vitellogenin", "." ]

[ 12, 13, 0, 8, 13, 12, 13, 16, 0, 16, 8, 13, 12, 13, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 0 ]

[ "However", ",", "perhaps", "over", "a", "longer", "term", ",", "the", "ability", "of", "highly", "toxic", "bacteria", "to", "resist", "the", "effects", "of", "nasal", "-", "associated", "immunity", "by", "killing", "host", "immune", "cells", ",", "and", "the", "use", "of", "some", "toxins", "(", "e.g.", ",", "the", "phenol", "soluble", "modulins", ",", "PSMs", ")", "to", "interfere", "with", "competing", "genera", "of", "bacteria", ",", "is", "key", "to", "its", "maintained", "selection", "." ]

[ 2, 13, 2, 1, 6, 0, 8, 13, 6, 8, 1, 2, 0, 8, 1, 16, 6, 8, 1, 8, 13, 16, 8, 1, 16, 8, 0, 8, 13, 5, 6, 8, 1, 6, 8, 13, 17, 13, 6, 8, 0, 8, 13, 12, 13, 1, 16, 1, 16, 8, 1, 8, 13, 3, 0, 1, 11, 16, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Subsequently", ",", "the", "bile", "duct", "was", "cannulated", "with", "a", "tube", "(", "0.8", "mm", "OD", ",", "5", "mm", "long", ")", "for", "biliary", "anastomosis", ",", "the", "portal", "vein", "(", "PV", ")", "was", "liberated", ",", "and", "the", "pyloric", "vein", "was", "ligated", "near", "the", "PV", ".", "The", "artery", "was", "liberated", "from", "the", "PHA", "to", "the", "celiac", "axis", ",", "and", "branches", ",", "such", "as", "splenic", "artery", ",", "left", "gastric", "artery", ",", "and", "gastroduodenal", "artery", "(", "GDA", ")", "were", "ligated", "and", "dissected", "." ]

[ 2, 13, 6, 8, 8, 3, 16, 1, 6, 8, 13, 9, 8, 8, 13, 9, 8, 0, 13, 1, 0, 8, 13, 6, 8, 8, 13, 12, 13, 3, 16, 13, 5, 6, 0, 8, 3, 16, 1, 6, 12, 13, 6, 8, 3, 16, 1, 6, 12, 1, 6, 0, 8, 13, 5, 8, 13, 0, 1, 0, 8, 13, 0, 0, 8, 13, 5, 0, 8, 13, 12, 13, 3, 16, 5, 16, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "Abbreviations", ":", "ATCC", ",", "American", "Type", "Culture", "Collection", ";", "DSMZ", ",", "Deutsche", "Sammlung", "von", "Mikroorganismen", "und", "Zellkulturen", ";", "wild", "WT", "-", "type", "." ]

[ 8, 13, 12, 13, 12, 12, 12, 12, 13, 12, 13, 12, 12, 1, 12, 5, 12, 13, 0, 12, 13, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 1, 4, 4, 0 ]

[ "Dipeptidyl", "peptidase-4", "(", "DPP-4", ")", "is", "a", "glycoprotein", "peptidase", "broadly", "expressed", "in", "various", "cell", "types", "which", "displays", "complex", "biological", "actions", "and", "has", "multiple", "functions", "[", "9–12", "]", "." ]

[ 8, 8, 13, 12, 13, 3, 6, 8, 8, 2, 16, 1, 0, 8, 8, 11, 16, 0, 0, 8, 5, 16, 0, 8, 17, 9, 13, 13 ]

[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "To", "assess", "intra-", "and", "interrater", "reliability", ",", "intraclass", "correlation", "coefficient", "(", "ICC", ")", "was", "calculated", "(", "two", "way", "mixed", "models", ",", "absolute", "agreement", "and", "single", "measurements", ")", ",", "considering", "an", "ICC", "of", "≥0.70", "as", "adequate", "[", "13", "]", "." ]

[ 10, 16, 0, 5, 0, 8, 13, 0, 8, 8, 13, 12, 13, 3, 16, 13, 9, 8, 16, 8, 13, 0, 8, 5, 0, 8, 13, 13, 16, 6, 12, 1, 9, 1, 0, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Note", "the", "stripedness", "-", "induced", "decoupling", "of", "the", "aVis+", "cells", "from", "the", "V2", "beta", "and", "low", "-", "gamma", "bands", ".", "aVis", ",", "active", "visual", "cortex", ";", "CPu", ",", "caudate", "putamen", ";", "LFP", ",", "local", "field", "potential", ";", "mCtx", ",", "motor", "cortex", ";", "SUA", ",", "single", "-", "unit", "activity", ";", "V2", ",", "secondary", "visual", "cortex", "." ]

[ 16, 6, 8, 13, 16, 8, 1, 6, 12, 8, 1, 6, 12, 8, 5, 0, 13, 8, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 0, 8, 13, 12, 13, 0, 8, 8, 13, 8, 13, 8, 8, 13, 12, 13, 0, 13, 8, 8, 13, 12, 13, 0, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 4, 0 ]

[ "Peptides", "were", "fractionated", "by", "basic", "Reverse", "Phase", "-", "High", "Performance", "Liquid", "Chromatographic", "(", "RP-HPLC", ")", ";", "the", "peptides", "prepared", "were", "reconstituted", "in", "20", "mM", "ammonium", "formate", "(", "pH", "10.0", ")", "." ]

[ 8, 3, 16, 1, 0, 12, 12, 13, 12, 12, 12, 12, 13, 12, 13, 13, 6, 8, 16, 3, 16, 1, 9, 8, 8, 8, 13, 8, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "VMconSz", "=", "visuomotor", "congruence", "with", "different", "sizes", "." ]

[ 12, 16, 0, 8, 1, 0, 8, 13 ]

[ 1, 0, 3, 4, 4, 4, 4, 0 ]

[ "CHR", ";", "crude", "hazard", "ratio", ",", "AHR", ";", "adjusted", "hazard", "ratio", ",", "TB", ";", "Tuberculosis", ",", "WHO", ";", "World", "Health", "Organization", ",", "Hgb", ";", "hemoglobin", ",", "BMI", ";", "Body", "Mass", "Index", ",", "HAART", ";", "Highly", "Active", "Anti", "-", "Retroviral", "Treatment", ",", "IPT", ";", "Isoniazid", "Preventive", "Therapy", ",", "ART", ";", "Anti", "-", "Retroviral", "Therapy", ",", "co", "-", "infection", ";", "the", "presence", "of", "is", "any", "comorbidity", "or", "infection", "other", "than", "tuberculosis", "." ]

[ 12, 13, 0, 8, 8, 13, 12, 13, 16, 8, 8, 13, 12, 13, 8, 13, 12, 13, 12, 12, 12, 13, 12, 13, 8, 13, 12, 13, 8, 12, 12, 13, 12, 13, 2, 12, 12, 8, 12, 12, 13, 12, 13, 12, 12, 12, 13, 12, 13, 12, 8, 12, 12, 13, 8, 8, 8, 13, 6, 8, 1, 3, 6, 8, 5, 8, 0, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0 ]

[ "Clinical", "examinations", "included", "a", "slit", "-", "lamp", "investigation", ",", "Ocular", "Surface", "Disease", "Index", "(", "OSDI", ")", "questionnaire", "scores", ",", "tear", "film", "break", "-", "up", "time", "(", "TBUT", ")", ",", "corneal", "fluorescein", "staining", "(", "CFS", ")", ",", "and", "Schirmer", "’s", "I", "test", "(", "SIT", ")", ".", "Diagnosis", "of", "DES", "included", "OSDI", "scores", "higher", "than", "15", ",", "SIT", "values", "lower", "than", "7", "mm", ",", "and", "TBUT", "values", "shorter", "than", "7", "s[16", "]", "." ]

[ 0, 8, 16, 6, 0, 13, 8, 8, 13, 12, 12, 12, 12, 13, 12, 13, 8, 8, 13, 8, 8, 8, 13, 1, 8, 13, 12, 13, 13, 0, 8, 8, 13, 12, 13, 13, 5, 12, 10, 8, 8, 13, 12, 13, 13, 8, 1, 12, 16, 12, 8, 0, 1, 9, 13, 12, 8, 0, 1, 9, 8, 13, 5, 12, 8, 0, 1, 9, 17, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "During", "RA", "progression", ",", "FLS", "grow", "without", "contact", "inhibition", "following", "morphology", "changing", ",", "express", "high", "levels", "of", "biomarkers", "such", "as", "c", "-", "fos", ",", "Jun", "-", "B", ",", "egr-1", "and", "matrix", "metalloprotease", "(", "MMP)-3", "[", "6", "]", ",", "and", "secretes", "several", "inflammatory", "cytokines", ",", "such", "as", "IL-6", ",", "IL-8", ",", "IL-1", ",", "TNF", "-", "α", "and", "MCP-1", "[", "7", ",", "8", "]", "." ]

[ 1, 12, 8, 13, 12, 16, 1, 8, 8, 16, 8, 8, 13, 16, 0, 8, 1, 8, 0, 1, 8, 8, 8, 13, 8, 8, 8, 13, 8, 5, 8, 8, 13, 12, 13, 9, 13, 13, 5, 16, 0, 0, 8, 13, 0, 1, 8, 13, 8, 13, 8, 13, 8, 8, 13, 5, 8, 13, 9, 13, 9, 13, 13 ]

[ 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "slow", "release", "of", "inorganic", "phosphate", "(", "Pi", ")", "that", "follows", "rapid", "cleavage", "of", "ATP", "gamma", "phosphate", "is", "linked", "to", "an", "increase", "in", "the", "rate", "of", "filament", "disassembly", "." ]

[ 6, 0, 8, 1, 0, 8, 13, 12, 13, 11, 16, 0, 8, 1, 12, 8, 8, 3, 16, 1, 6, 8, 1, 6, 8, 1, 8, 8, 13 ]

[ 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Although", "screening", "of", "blood", "by", "nucleic", "acid", "test", "(", "NAT", ")", "is", "currently", "mandated", "by", "the", "FDA", ",", "actual", "implementation", "of", "screening", "strategies", "is", "largely", "at", "the", "discretion", "of", "the", "individual", "states", "and", "the", "blood", "-", "collection", "agencies", "." ]

[ 14, 8, 1, 8, 1, 0, 8, 8, 13, 12, 13, 3, 2, 16, 1, 6, 12, 13, 0, 8, 1, 8, 8, 3, 2, 1, 6, 8, 1, 6, 0, 8, 5, 6, 8, 13, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "For", "heparan", "sulfate", "(", "HS", ")", ",", "RFPEC", "monolayers", "treated", "with", "2", "%", "paraformaldehyde/1", "%", "glutaraldehyde", "in", "phosphate", "buffered", "saline", "(", "PBS", ")", "for", "fixation", "and", "treated", "with", "2", "%", "goat", "serum", "in", "PBS", "to", "block", "non", "-", "specific", "ligands", ",", "were", "stained", "for", "three", "nights", "at", "4", "°", "C", "with", "a", "1:100", "10E4", "-", "epitope", "HS", "antibody", "(", "Amsbio", ")", "." ]

[ 1, 8, 8, 13, 12, 13, 13, 12, 8, 16, 1, 9, 8, 8, 8, 8, 1, 8, 16, 8, 13, 12, 13, 1, 8, 5, 16, 1, 9, 8, 8, 8, 1, 12, 10, 16, 0, 13, 0, 8, 13, 3, 16, 1, 9, 8, 1, 9, 8, 8, 1, 6, 9, 9, 13, 8, 12, 8, 13, 12, 13, 13 ]

[ 0, 3, 4, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "BPH", ":", "Benign", "Prostatic", "Hypertrophy", ",", "PCa", ":", "Prostate", "cancer", "." ]

[ 12, 13, 0, 0, 8, 13, 12, 13, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0 ]

[ "With", "regard", "to", "cancer", "mortality", ",", "in", "contrast", ",", "a", "potential", "reason", "for", "the", "positive", "association", "between", "adult", "height", "and", "cancer", "mortality", "is", "explained", "by", "levels", "of", "insulin", "-", "like", "growth", "factor-1", "(", "IGF-1", ")", "[", "20–23", "]", ",", "which", "are", "related", "to", "the", "promotion", "of", "cell", "proliferation", "and", "inhibition", "of", "apoptosis", "[", "24", "]", "." ]

[ 1, 8, 1, 8, 8, 13, 1, 8, 13, 6, 0, 8, 1, 6, 0, 8, 1, 8, 8, 5, 8, 8, 3, 16, 1, 8, 1, 8, 13, 0, 8, 8, 13, 12, 13, 13, 9, 13, 13, 11, 3, 16, 1, 6, 8, 1, 8, 8, 5, 8, 1, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "This", "suggests", "that", "the", "characteristics", "of", "the", "original", "ACE", "network", "(", "Fig", "4A", ")", ",", "and", "thus", "the", "efficacy", "of", "drug", "combinations", "to", "reduce", "adaptation", "rates", ",", "is", "primarily", "driven", "by", "adaptation", "to", "the", "stronger", "component", ",", "which", "—", "if", "accounted", "for", "by", "the", "standardizing", "scheme", "—", "removes", "important", "properties", "of", "the", "network", "(", "see", "as", "prominent", "examples", "the", "disappearance", "of", "the", "strong", "reduction", "in", "adaptation", "rate", "for", "doripenem", "[", "DOR", "]", "plus", "TIC", ",", "or", "DOR", "plus", "PIT", "[", "piperacillin", "+", "tazobactam", "]", ";", "Fig", "4A", "and", "Fig", "6A", ")", "." ]

[ 11, 16, 14, 6, 8, 1, 6, 0, 12, 8, 13, 12, 9, 13, 13, 5, 2, 6, 8, 1, 8, 8, 1, 16, 8, 8, 13, 3, 2, 16, 1, 8, 1, 6, 0, 8, 13, 11, 13, 14, 16, 1, 1, 6, 8, 8, 13, 16, 0, 8, 1, 6, 8, 13, 16, 1, 0, 8, 6, 8, 1, 6, 0, 8, 1, 8, 8, 1, 8, 13, 12, 13, 5, 12, 13, 5, 12, 5, 12, 13, 8, 5, 8, 13, 13, 12, 9, 5, 12, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 1, 0, 0, 1, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "If", ",", "in", "addition", "to", "knowing", "the", "ACH", "and", "the", "air", "flow", "pattern", ",", "the", "characteristics", "of", "the", "contaminant", "and", "the", "point", "of", "emission", "are", "also", "known", ",", "then", "the", "contaminant", "removal", "effectiveness", "index", "(", "εc", ")", "can", "be", "used", "." ]

[ 14, 13, 1, 8, 1, 16, 6, 12, 5, 6, 8, 8, 8, 13, 6, 8, 1, 6, 8, 5, 6, 8, 1, 8, 3, 2, 16, 13, 2, 6, 8, 8, 8, 8, 13, 12, 13, 3, 3, 16, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "Under", "this", "non", "-", "inferiority", "design", ",", "the", "failure", "rate", "for", "the", "NVP", "-", "exposed", "group", "would", "be", "considered", "equivalent", "to", "that", "of", "the", "NVP", "-", "unexposed", "group", "if", "the", "upper", "bound", "of", "the", "95", "%", "confidence", "interval", "(", "CI", ")", "for", "the", "difference", "between", "groups", "did", "not", "exceed", "10", "%", "." ]

[ 1, 6, 0, 13, 0, 8, 13, 6, 8, 8, 1, 6, 12, 13, 16, 8, 3, 3, 16, 0, 1, 11, 1, 6, 12, 13, 0, 8, 14, 6, 0, 8, 1, 6, 9, 13, 8, 8, 13, 12, 13, 1, 6, 8, 1, 8, 3, 10, 16, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "ACT", ",", "Artemisinin", "Combination", "Therapy", ";", "SPA", ",", "Service", "Provision", "Assessment", "." ]

[ 12, 13, 12, 12, 12, 13, 12, 13, 12, 12, 8, 13 ]

[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0 ]

[ "CreERT", ",", "ubiquitous", "promoter", "-", "driven", "Cre", "-", "recombinase", "and", "estrogen", "-", "receptor", "fusion", "protein", ";", "FC", ",", "FoxN1fx", "/", "fx", "/", "CreERT", "CreERT", ";", "FoxN1", ",", "Forkhead", "box", "protein", "N1", ";", "FoxN1fx", "/", "fx", ",", "loxp", "-", "flanked", "FoxN1", "gene", ";", "IL-2", ",", "interleukin-2", ";", "NF", ",", "Nuclear", "Factor", "kappa", "Beta", ";", "-κBRT", ",", "reverse", "transcribed", ";", "PCR", ",", "polymerase", "chain", "reaction", ";", "tTreg", ",", "thymic", "regulatory", "T", "cell", "." ]

[ 12, 13, 0, 8, 8, 16, 8, 8, 8, 5, 8, 8, 8, 8, 8, 13, 12, 13, 12, 15, 8, 15, 12, 12, 13, 12, 13, 8, 8, 8, 12, 13, 12, 15, 8, 13, 8, 8, 16, 12, 8, 13, 12, 13, 8, 13, 12, 13, 12, 12, 8, 8, 13, 12, 13, 2, 16, 13, 12, 13, 8, 8, 8, 13, 12, 13, 0, 0, 8, 8, 13 ]

[ 1, 0, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 1, 0, 1, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 3, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0 ]

[ "However", ",", "conversion", "rates", "are", "low", "on", "a", "diet", "rich", "in", "linoleic", "acid", "(", "C18:2", "n6", ",", "LA", ")", ",", "as", "it", "is", "the", "case", "for", "a", "typical", "western", "diet", "(", "soy", ",", "corn", "and", "sunflower", "oil", "based", ")", "[", "17", "]", "." ]

[ 2, 13, 8, 8, 3, 0, 1, 6, 8, 0, 1, 0, 8, 13, 8, 8, 13, 12, 13, 13, 14, 11, 3, 6, 8, 1, 6, 0, 0, 8, 13, 8, 13, 8, 5, 8, 8, 16, 13, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Active", "Case", "Finding", "for", "Tuberculosis", "through", "TOUCH", "Agents", "in", "Selected", "High", "TB", "Burden", "Wards", "of", "Kolkata", ",", "India", ":", "A", "Mixed", "Methods", "Study", "on", "Outcomes", "and", "Implementation", "Challenges", "." ]

[ 0, 8, 8, 1, 8, 1, 8, 8, 1, 16, 0, 12, 8, 8, 1, 12, 13, 12, 13, 6, 0, 8, 8, 1, 8, 5, 8, 8, 13 ]

[ 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Body", "mass", "index", "(", "BMI", ")", "was", "calculated", "as", "weight", "in", "kilograms", "divided", "by", "height", "in", "meter", "squared", "." ]

[ 8, 8, 8, 13, 12, 13, 3, 16, 1, 8, 1, 8, 16, 1, 8, 1, 8, 16, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Three", "different", "types", "of", "fat", "tissue", "exist", "of", "which", "brown", "adipose", "tissue", "(", "BAT", ")", ",", "mostly", "present", "in", "embryonic", "and", "fetal", "stages", ",", "and", "beige", "adipose", "tissue", "(", "BET", ")", "present", "postnatally", ",", "utilize", "glucose", "and", "lipids", "to", "generate", "heat", ",", "and", "are", "associated", "with", "improved", "cardiometabolic", "health", "[", "7", "]", "." ]

[ 9, 0, 8, 1, 8, 8, 16, 1, 11, 0, 0, 8, 13, 12, 13, 13, 2, 0, 1, 0, 5, 0, 8, 13, 5, 0, 0, 8, 13, 12, 13, 0, 2, 13, 16, 8, 5, 8, 10, 16, 8, 13, 5, 3, 16, 1, 0, 0, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "MFO", ":", "Maximal", "Fat", "Oxidation", "." ]

[ 12, 13, 0, 8, 8, 13 ]

[ 1, 0, 3, 4, 4, 0 ]

[ "The", "preferred", "feature", "of", "each", "simple", "cell", "(", "Figure", "4A", ",", "inset", ")", ",", "which", "directly", "corresponds", "to", "the", "classical", "RF", "of", "the", "cell", ",", "was", "estimated", "with", "a", "modified", "spike", "-", "triggered", "average", "(", "STA", ")", "analysis", "that", "corrects", "for", "the", "spatial", "correlations", "in", "natural", "images", "[", "23,36", "]", "(", "see", "Materials", "and", "Methods", ")", "." ]

[ 6, 16, 8, 1, 6, 0, 8, 13, 8, 9, 13, 8, 13, 13, 11, 2, 16, 1, 6, 0, 12, 1, 6, 8, 13, 3, 16, 1, 6, 16, 8, 13, 16, 8, 13, 12, 13, 8, 11, 16, 1, 6, 0, 8, 1, 0, 8, 17, 17, 17, 13, 16, 12, 5, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "BMI", ",", "body", "mass", "index", ";", "FFMI", ",", "fat", "-", "free", "mass", "index", ";", "FMI", ",", "fat", "mass", "index", ";", "MR", ",", "mendelian", "randomisation", ";", "OR", ",", "odds", "ratio", "." ]

[ 12, 13, 8, 8, 8, 13, 12, 13, 0, 13, 0, 8, 8, 13, 12, 13, 0, 8, 8, 13, 12, 13, 0, 8, 13, 12, 13, 8, 8, 13 ]

[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 0 ]

[ "The", "percentage", "of", "CD8", "+", "and", "CD4", "+", "T", "cells", "expressing", "CD30", "and", "CD69", "are", "shown", "in", "(", "A", ")", "and", "(", "B", ")", ".", "The", "percentage", "of", "CD16", "+", "and", "CD56", "+", "NK", "cells", "expressing", "CD30", "and", "CD69", "are", "shown", "in", "(", "C", ")", "and", "(", "D", ")", ".", "T", "cell", "expression", "of", "CD30", "from", "the", "allogeneic", "HSCT", "recipient", "who", "also", "underwent", "ATI", "is", "shown", "in", "(", "E", ")", ".", "Abbreviations", ":", "ATI", ",", "analytical", "treatment", "interruption", ";", "c", "/", "mL", ",", "copies", "/", "mL", ";", "HSCT", ",", "hematopoietic", "stem", "cell", "transplantation", ";", "NK", ",", "natural", "killer", ";", "PrEP", ",", "pre", "-", "exposure", "prophylaxis", "." ]

[ 6, 8, 1, 8, 8, 5, 8, 8, 8, 8, 16, 8, 5, 8, 3, 16, 1, 13, 8, 13, 5, 13, 8, 13, 13, 6, 8, 1, 8, 8, 5, 8, 8, 12, 8, 16, 8, 5, 8, 3, 16, 1, 13, 8, 13, 5, 13, 8, 13, 13, 8, 8, 8, 1, 8, 1, 6, 0, 12, 8, 11, 2, 16, 12, 3, 16, 1, 13, 8, 13, 13, 8, 13, 12, 13, 0, 8, 8, 13, 8, 15, 8, 13, 8, 15, 8, 13, 12, 13, 0, 8, 8, 8, 13, 12, 13, 0, 8, 13, 12, 13, 0, 0, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 4, 0 ]