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When was Everton's most recent trophy awarded? | 1995 | 28,642 |
The Grand Lodges of Scotland and Ireland have how many member? | approximately 150,000 members | 38,047 |
What was one of the requirements for a new standard system in the US? | had to be more efficient, needing less bandwidth | 22,467 |
What product significantly dropped in price at the end of World War I? | natural rubber | 50,297 |
In what year was the city in conflict with two nearby tribes? | 494 BC | 77,997 |
What was the name for the time period? | Renaissance | 10,925 |
In what year did St. John's have a population of 214,285? | 2015 | 62,065 |
What is (are) complement factor I deficiency ? | Complement factor I deficiency is a disorder that affects the immune system. People with this condition are prone to recurrent infections, including infections of the upper respiratory tract, ears, skin, and urinary tract. They may also contract more serious infections such as pneumonia, meningitis, and sepsis, which may be life-threatening. Some people with complement factor I deficiency have a kidney disorder called glomerulonephritis with isolated C3 deposits. Complement factor I deficiency can also be associated with autoimmune disorders such as rheumatoid arthritis or systemic lupus erythematosus (SLE). Autoimmune disorders occur when the immune system malfunctions and attacks the body's tissues and organs. | 98,527 |
What does PRISM do? | provides for broad monitoring of Internet users traffic | 14,010 |
Who eradicated the Sakya viceregal regime? | the Phagmodru myriarch Tai Situ Changchub Gyaltsen | 2,220 |
What kind of group runs The Procession? | non-profit arts organization | 76,776 |
The New Delhi Municipal Government oversees what large Indian city? | New Delhi | 24,617 |
What did the Thuringian miners do to help the Soviet Union? | uranium mining was also important to cover the Soviet Union's need for this metal | 45,622 |
What are the symptoms of Lopes Gorlin syndrome ? | What are the signs and symptoms of Lopes Gorlin syndrome? The Human Phenotype Ontology provides the following list of signs and symptoms for Lopes Gorlin syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Distichiasis 90% Photophobia 50% Absent lower eyelashes - Autosomal dominant inheritance - Hypoplasia of the lower eyelids - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common. | 114,052 |
What is the purpose of an evolutionary arms race? | keep the populations of both species in equilibrium | 45,721 |
What other theater is in the Duke Energy Center? | Fletcher Opera Theater | 51,605 |
The former 132nd Street Bus Depot is located between Broadway and what other drive in the Manhattanville neighborhood? | Riverside Drive | 21,627 |
Why does Hegel believe we cannot know God? | we are finite beings | 69,490 |
What determined whether The Bahre-Nagassi fought with or against the Abyssinians? | geopolitical circumstances | 33,392 |
What is (are) Head Lice ? | Head lice are parasitic wingless insects. They live on people's heads and feed on their blood. An adult louse is about the size of a sesame seed. The eggs, called nits, are even smaller - about the size of a knot in thread. Lice and nits are found on or near the scalp, most often at the neckline and behind the ears. Lice spread by close person-to-person contact. It is possible, but not common, to get lice by sharing personal belongings such as hats or hairbrushes. Children ages 3-11 and their families get head lice most often. Personal hygiene has nothing to do with getting head lice. Head lice do not spread disease. Symptoms are - Tickling feeling in the hair - Frequent itching - Sores from scratching - Irritability and difficulty sleeping. Head lice are most active in the dark. Treatment is recommended for people who have an active infestation of head lice. All household members and other close contacts should be checked and treated if necessary. Some experts also recommend treating anyone who shares a bed with an infested person. It is important to treat everyone at the same time. Centers for Disease Control and Prevention | 117,953 |
What type of activity did early settlers use to get food that didn't involve farming? | fishing | 9,375 |
Where do many Air Force families live? | Rita Ranch | 76,699 |
What is one of SASO's main goals? | providing a final solution to the question of how to best measure sexual orientation | 34,659 |
How of Charleston's total area is dry land? | 109.0 square miles (282.2 km2) | 72,327 |
What is used to confirm the diagnosis of asthma? | Spirometry | 62,859 |
One of the most important business in which Shell is involved is what? | natural gas | 41,857 |
What city saw the largest growth? | Kalispell | 1,139 |
What type of language is French considered to be? | Romance languages | 78,212 |
What position in the army did he become after office school? | sergeant | 19,633 |
What to do for Cirrhosis ? | A healthy diet is important in all stages of cirrhosis because malnutrition is common in people with this disease. Malnutrition is a condition that occurs when the body does not get enough nutrients. Cirrhosis may lead to malnutrition because it can cause
- people to eat less because of symptoms such as loss of appetite - changes in metabolism - reduced absorption of vitamins and minerals
Health care providers can recommend a meal plan that is well balanced and provides enough calories and protein. If ascites develops, a health care provider or dietitian may recommend a sodium-restricted diet. To improve nutrition, the health care provider may prescribe a liquid supplement. A person may take the liquid by mouth or through a nasogastric tubea tiny tube inserted through the nose and throat that reaches into the stomach.
A person with cirrhosis should not eat raw shellfish, which can contain a bacterium that causes serious infection. Cirrhosis affects the immune system, making people with cirrhosis more likely than healthy people to develop an infection after eating shellfish that contain this bacterium.
A health care provider may recommend calcium and vitamin D supplements to help prevent osteoporosis. | 120,331 |
What was the biggest Hollywood studio during this period? | Universal | 13,438 |
What is the name for a lamp base with one or more contacts on the base and a shell used as a contact or used only as a mechanical support? | bayonet base | 40,917 |
What floor of the Chrysler Building has sculptures of eagles at its corners? | 61st | 4,056 |
Which empire sent armies to attack Ban Chao? | Kushan | 73,546 |
How many pairs of ganglia are in a segment? | one pair | 64,779 |
Who owns the land on which Irish comprehensive schools are found? | The state | 9,591 |
Is hereditary fructose intolerance inherited ? | This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. | 95,230 |
Is tibial muscular dystrophy inherited ? | This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. | 96,860 |
What is (are) Autoimmune Diseases ? | Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling. The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response. | 117,605 |
What form of political organization do Popper's works mainly critique? | totalitarianism | 64,299 |
Lieberman and Jackson suggest authors of some studies use the term race in what ways? | conceptually imprecise and careless | 65,080 |
What campus of University of Maryland is listed on the National Register of Historic Places? | College Park campus | 17,766 |
What hairstyle did Mithridates IV copy from Alexander? | anastole | 38,644 |
What are the two standard antenna types? | omnidirectional or weakly directional | 75,218 |
What is the surface area of the Sahara Desert? | 9,400,000 square kilometres (3,600,000 sq mi) | 59,996 |
What is (are) Congenital porphyria ? | Congenital erythropoietic porphyria (CEP) is the rarest porphyria and is commonly seen in infancy, although it may begin in adulthood. It is characterized by severe skin photosensitivity that may lead to scarring, blistering, and increased hair growth at the face and back of the hands. Photosensitivity and infection may cause the loss of fingers and facial features. Symptoms of CEP range from mild to severe and may include hypertrichosis, reddish discoloration of the teeth, anemia, and reddish-colored urine. In CEP, there is a defect in the synthesis of heme within the red blood cells of bone marrow. This defect leads to an increase in the buildup and, therefore, waste of porphyrin and its precursors, which leads to the signs and symptoms. Treatment for CEP may include activated charcoal or a bone marrow transplant, which can improve the anemia and future blister or scar formations from photosensitivity. Blood transfusions or spleen removal may also reduce the amount of porphyrin produced from bone marrow. This condition is inherited in an autosomal recessive fashion and is caused by mutations in the UROS gene. | 113,102 |
What was manufactured completely from petrochemicals? | Nylon | 47,956 |
What is yet another application for which organisms have been modified for? | medicine | 21,201 |
What is (are) Hyperthyroidism ? | Your thyroid is a butterfly-shaped gland in your neck, just above your collarbone. It is one of your endocrine glands, which make hormones. Thyroid hormones control the rate of many activities in your body. These include how fast you burn calories and how fast your heart beats. All of these activities are your body's metabolism. If your thyroid is too active, it makes more thyroid hormones than your body needs. This is called hyperthyroidism. Hyperthyroidism is more common in women, people with other thyroid problems, and those over 60 years old. Grave's disease, an autoimmune disorder, is the most common cause. Other causes include thyroid nodules, thyroiditis, consuming too much iodine, and taking too much synthetic thyroid hormone. The symptoms can vary from person to person. They may include - Being nervous or irritable - Mood swings - Fatigue or muscle weakness - Heat intolerance - Trouble sleeping - Hand tremors - Rapid and irregular heartbeat - Frequent bowel movements or diarrhea - Weight loss - Goiter, which is an enlarged thyroid that may cause the neck to look swollen To diagnose hyperthyroidism, your doctor will look at your symptoms, blood tests, and sometimes a thyroid scan. Treatment is with medicines, radioiodine therapy, or thyroid surgery. No single treatment works for everyone. NIH: National Institute of Diabetes and Digestive and Kidney Diseases | 93,155 |
Who did Burke turn down money from? | Fitzwilliam | 50,156 |
What is the official Cubs team mascot? | a young bear cub | 41,305 |
What is (are) fragile X-associated tremor/ataxia syndrome ? | Fragile X-associated tremor/ataxia syndrome (FXTAS) is characterized by problems with movement and thinking ability (cognition). FXTAS is a late-onset disorder, usually occurring after age 50, and its signs and symptoms worsen with age. This condition affects males more frequently and severely than females. Affected individuals have areas of damage in the part of the brain that controls movement (the cerebellum) and in a type of brain tissue known as white matter, which can be seen with magnetic resonance imaging (MRI). This damage leads to the movement problems and other impairments associated with FXTAS. The characteristic features of FXTAS are intention tremor, which is trembling or shaking of a limb when trying to perform a voluntary movement such as reaching for an object, and problems with coordination and balance (ataxia). Typically intention tremors will develop first, followed a few years later by ataxia, although not everyone with FXTAS has both features. Many affected individuals develop other movement problems, such as a pattern of movement abnormalities known as parkinsonism, which includes tremors when not moving (resting tremor), rigidity, and unusually slow movement (bradykinesia). In addition, affected individuals may have reduced sensation, numbness or tingling, pain, or muscle weakness in the lower limbs. Some people with FXTAS experience problems with the autonomic nervous system, which controls involuntary body functions, leading to the inability to control the bladder or bowel. People with FXTAS commonly have cognitive disabilities. They may develop short-term memory loss and loss of executive function, which is the ability to plan and implement actions and develop problem-solving strategies. Loss of this function impairs skills such as impulse control, self-monitoring, focusing attention appropriately, and cognitive flexibility. Many people with FXTAS experience anxiety, depression, moodiness, or irritability. Some women develop immune system disorders, such as hypothyroidism or fibromyalgia, before the signs and symptoms of FXTAS appear. | 95,902 |
What is (are) hypomagnesemia with secondary hypocalcemia ? | Hypomagnesemia with secondary hypocalcemia is an inherited condition caused by the body's inability to absorb and retain magnesium that is taken in through the diet. As a result, magnesium levels in the blood are severely low (hypomagnesemia). Hypomagnesemia impairs the function of the parathyroid glands, which are small hormone-producing glands located in the neck. Normally, the parathyroid glands release a hormone that increases blood calcium levels when they are low. Magnesium is required for the production and release of parathyroid hormone, so when magnesium is too low, insufficient parathyroid hormone is produced and blood calcium levels are also reduced (hypocalcemia). The hypocalcemia is described as "secondary" because it occurs as a consequence of hypomagnesemia. Shortages of magnesium and calcium can cause neurological problems that begin in infancy, including painful muscle spasms (tetany) and seizures. If left untreated, hypomagnesemia with secondary hypocalcemia can lead to developmental delay, intellectual disability, a failure to gain weight and grow at the expected rate (failure to thrive), and heart failure. | 97,582 |
What does the MoD wish to strengthen? | international peace and stability | 22,307 |
What is (are) WAGR syndrome ? | WAGR syndrome is a genetic syndrome in which there is a predisposition to several conditions, including certain malignancies, distinctive eye abnormalities, and/or mental retardation. WAGR is an acronym for Wilms tumor, Aniridia, Genitourinary anomalies (such as undescended testicles or hypospadias in males, or internal genital or urinary anomalies in females), mental Retardation syndrome. A combination of two or more of these conditions is usually present in most individuals with WAGR syndrome. The syndrome is due to a microdeletion in the 11p13 region of chromosome 11. In most cases, this genetic change occurs spontaneously during early embryonic development (de novo) for unknown reasons (sporadic). Only rarely is the mutation inherited. | 111,447 |
How was sensitivity expressed at first in the DIN system? | as a fraction with 'tenths' (for example "18/10° DIN") | 43,174 |
What are the risks of wrestling? | high chance of injury, and even death | 43,143 |
Who is credited with increasing the safety and speed of electric elevators? | Frank Sprague | 71,670 |
What are the main attractions in Cork? | Cork Opera House (capacity c.1000), Cyprus Avenue, Triskel Christchurch, the Roundy, the Savoy and Coughlan's | 58,575 |
By 1992 who was Barcelona's most successful manager? | Cruyff | 28,416 |
What provides a degree of protection from interference with the USB signal? | This enclosure design | 59,211 |
Art and music were some of these forms of cultural related to what type of living? | urban life | 59,948 |
What is Taiwanese in Northern Taiwan based on? | Quanzhou | 39,703 |
What is (are) North American Indian childhood cirrhosis ? | North American Indian childhood cirrhosis is a rare liver disorder that occurs in children. The liver malfunction causes yellowing of the skin and whites of the eyes (jaundice) in affected infants. The disorder worsens with age, progressively damaging the liver and leading to chronic, irreversible liver disease (cirrhosis) in childhood or adolescence. Unless it is treated with liver transplantation, North American Indian childhood cirrhosis typically causes life-threatening complications including liver failure. | 95,827 |
How many seats does the Pregones' new theater have? | 130 | 86,204 |
The modern land area was created by the gradual filling in of surrounding what? | tidal areas | 14,896 |
What are the symptoms of Glomerulopathy with fibronectin deposits 2 ? | What are the signs and symptoms of Glomerulopathy with fibronectin deposits 2? The Human Phenotype Ontology provides the following list of signs and symptoms for Glomerulopathy with fibronectin deposits 2. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Edema of the lower limbs 90% Glomerulopathy 90% Hematuria 90% Hypertension 90% Nephrotic syndrome 90% Proteinuria 90% Renal insufficiency 90% Intracranial hemorrhage 7.5% Autosomal dominant inheritance - Generalized distal tubular acidosis - Microscopic hematuria - Renal cell carcinoma - Slow progression - Stage 5 chronic kidney disease - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common. | 99,934 |
Which direction of pass causes play to stop when it is not caught? | forward | 70,129 |
Which factors make Melbourne one of the moust vibrant destinations in Australia? | The climate, waterfront location and nightlife | 31,615 |
What is (are) DOORS syndrome ? | DOORS syndrome is a disorder involving multiple abnormalities that are present from birth (congenital). "DOORS" is an abbreviation for the major features of the disorder including deafness; short or absent nails (onychodystrophy); short fingers and toes (osteodystrophy); developmental delay and intellectual disability (previously called mental retardation); and seizures. Some people with DOORS syndrome do not have all of these features. Most people with DOORS syndrome have profound hearing loss caused by changes in the inner ears (sensorineural deafness). Developmental delay and intellectual disability are also often severe in this disorder. The nail abnormalities affect both the hands and the feet in DOORS syndrome. Impaired growth of the bones at the tips of the fingers and toes (hypoplastic terminal phalanges) account for the short fingers and toes characteristic of this disorder. Some affected individuals also have an extra bone and joint in their thumbs, causing the thumbs to look more like the other fingers (triphalangeal thumbs). The seizures that occur in people with DOORS syndrome usually start in infancy. The most common seizures in people with this condition are generalized tonic-clonic seizures (also known as grand mal seizures), which cause muscle rigidity, convulsions, and loss of consciousness. Affected individuals may also have other types of seizures, including partial seizures, which affect only one area of the brain and do not cause a loss of consciousness; absence seizures, which cause loss of consciousness for a short period that appears as a staring spell; or myoclonic seizures, which cause rapid, uncontrolled muscle jerks. In some affected individuals the seizures increase in frequency and become more severe and difficult to control, and a potentially life-threatening prolonged seizure (status epilepticus) can occur. Other features that can occur in people with DOORS syndrome include an unusually small head size (microcephaly) and facial differences, most commonly a wide, bulbous nose. A narrow or high arched roof of the mouth (palate), broadening of the ridges in the upper and lower jaw that contain the sockets of the teeth (alveolar ridges), or shortening of the membrane between the floor of the mouth and the tongue (frenulum) have also been observed in some affected individuals. People with DOORS syndrome may also have dental abnormalities, structural abnormalities of the heart or urinary tract, and abnormally low levels of thyroid hormones (hypothyroidism). Most affected individuals also have higher-than-normal levels of a substance called 2-oxoglutaric acid in their urine; these levels can fluctuate between normal and elevated. | 95,787 |
What has the KInsey scaled been praised for? | dismissing the dichotomous classification of sexual orientation and allowing for a new perspective on human sexuality. | 34,709 |
In 2002 what act granted full British citizenship to the citizens of the islands? | British Overseas Territories Act 2002 | 14,258 |
Which conquistador from Spain conquered the Aztec Empire? | Hernán Cortés | 72,627 |
How many subsidized cotton growers are in the US? | 25,000 | 47,987 |
What department store was founded in 1853? | Delany's New Mart | 44,822 |
What did authors and artists begin advocating for instead of the underground scene? | overground brightness | 70,007 |
What was Canada's date for the switch between analog and digital transmission? | August 31, 2011 | 67,232 |
What is the name of the county that Detroit is a part of? | Wayne County | 59,586 |
What was the name of the Philippine terrorist group the US was sent to help combat? | Abu Sayyaf | 29,615 |
Did his place more value on his Faith or where he was living? | the true Faith | 35,795 |
What did John William Bean try to fire at Queen Victoria? | paper and tobacco | 37,629 |
In what year did Ferguson publish An Essay on the History of Civil Society? | 1767 | 34,108 |
Which Latin father described the belief that Jesus' siblings were his cousins? | Jerome | 31,235 |
What are the genetic changes related to 7q11.23 duplication syndrome ? | 7q11.23 duplication syndrome results from an extra copy of a region on the long (q) arm of chromosome 7 in each cell. This region is called the Williams-Beuren syndrome critical region (WBSCR) because its deletion causes a different disorder called Williams syndrome, also known as Williams-Beuren syndrome. The region, which is 1.5 to 1.8 million DNA base pairs (Mb) in length, includes 26 to 28 genes. Extra copies of several of the genes in the duplicated region, including the ELN and GTF2I genes, likely contribute to the characteristic features of 7q11.23 duplication syndrome. Researchers suggest that an extra copy of the ELN gene in each cell may be related to the increased risk for aortic dilatation in 7q11.23 duplication syndrome. Studies suggest that an extra copy of the GTF2I gene may be associated with some of the behavioral features of the disorder. However, the specific causes of these features are unclear. Researchers are studying additional genes in the duplicated region, but none have been definitely linked to any of the specific signs or symptoms of 7q11.23 duplication syndrome. | 108,343 |
The hindbrain during development is known as what? | rhombencephalon | 21,717 |
Where did synods prohibit all hunting at? | Milan, Avignon, Liège, Cologne, and elsewhere | 87,069 |
What non winning major party nominees studied at Yale? | John Kerry (2004), Joseph Lieberman (Vice President, 2000), and Sargent Shriver (Vice President, 1972) | 48,970 |
Rather than a TV series, What kind of series would the Digimon become? | 6-part theatrical film series | 54,347 |
What year was a stagecoach bus line established in Montevideo? | 1853 | 39,788 |
Why some lines of Paris Metro have to operate on a four-rail system? | rubber tyres | 72,125 |
After the telegraph was extended to the coast of the Black Sea, how long did it take news of the war to reach London? | two days | 52,207 |
On which dates did La Semaine Sanglante occur in Paris? | 21–28 May | 33,334 |
Britain competed with which country to fill the Asian power vacuum in the 19th century? | Russian | 46,076 |
Along with Faith Hill, Shania Twain and LeAnn Rimes, what country artist has had adult contemporary hits? | Carrie Underwood | 16,499 |
How many people are affected by Meckel syndrome ? | Meckel syndrome affects 1 in 13,250 to 1 in 140,000 people worldwide. It is more common in certain populations; for example, the condition affects about 1 in 9,000 people of Finnish ancestry and about 1 in 3,000 people of Belgian ancestry. | 96,373 |
Where was the 'Continental model' of police from? | France | 86,601 |
What was built near Morovic for Tito to use in the event of his recovery? | Vila Srna | 19,822 |
Where is Charlotte motor Speedway located? | Concord | 55,974 |
Flies and what other kind of insect transmit diseases? | mosquitoes | 64,953 |
What are the treatments for hyperferritinemia-cataract syndrome ? | These resources address the diagnosis or management of hyperferritinemia-cataract syndrome: - Boston Children's Hospital: Cataracts in Children - Genetic Testing Registry: Hyperferritinemia cataract syndrome - MedlinePlus Encyclopedia: Cataract Removal These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care | 107,050 |