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Isabelle Stengers wrote that "Whiteheadians are recruited among both philosophers and theologians, and the palette has been enriched by practitioners from the most diverse horizons, from ecology to feminism, practices that unite political struggle and spirituality with the sciences of education." Indeed, in recent decades attention to Whitehead's work has become more widespread, with interest extending to intellectuals in Europe and China, and coming from such diverse fields as ecology, physics, biology, education, economics, and psychology. One of the first theologians to attempt to interact with Whitehead's thought was the future Archbishop of Canterbury, William Temple. In Temple's Gifford Lectures of 1932-1934 (subsequently published as "Nature, Man and God"), Whitehead is one of a number of philosophers of the emergent evolution approach Temple interacts with. However, it was not until the 1970s and 1980s that Whitehead's thought drew much attention outside of a small group of philosophers and theologians, primarily Americans, and even today he is not considered especially influential outside of relatively specialized circles.
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Process theology typically stresses God's relational nature. Rather than seeing God as impassive or emotionless, process theologians view God as "the fellow sufferer who understands", and as the being who is supremely affected by temporal events. Hartshorne points out that people would not praise a human ruler who was unaffected by either the joys or sorrows of his followers – so why would this be a praise-worthy quality in God? Instead, as the being who is most affected by the world, God is the being who can most appropriately respond to the world. However, process theology has been formulated in a wide variety of ways. C. Robert Mesle, for instance, advocates a "process naturalism", i.e. a process theology without God.
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Whitehead did not begin his career as a philosopher. In fact, he never had any formal training in philosophy beyond his undergraduate education. Early in his life he showed great interest in and respect for philosophy and metaphysics, but it is evident that he considered himself a rank amateur. In one letter to his friend and former student Bertrand Russell, after discussing whether science aimed to be explanatory or merely descriptive, he wrote: "This further question lands us in the ocean of metaphysic, onto which my profound ignorance of that science forbids me to enter." Ironically, in later life Whitehead would become one of the 20th century's foremost metaphysicians.
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Whitehead pointed to the limitations of language as one of the main culprits in maintaining a materialistic way of thinking, and acknowledged that it may be difficult to ever wholly move past such ideas in everyday speech. After all, each moment of each person's life can hardly be given a different proper name, and it is easy and convenient to think of people and objects as remaining fundamentally the same things, rather than constantly keeping in mind that each thing is a different thing from what it was a moment ago. Yet the limitations of everyday living and everyday speech should not prevent people from realizing that "material substances" or "essences" are a convenient generalized description of a continuum of particular, concrete processes. No one questions that a ten-year-old person is quite different by the time he or she turns thirty years old, and in many ways is not the same person at all; Whitehead points out that it is not philosophically or ontologically sound to think that a person is the same from one second to the next.
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Whitehead thus sees God and the world as fulfilling one another. He sees entities in the world as fluent and changing things that yearn for a permanence which only God can provide by taking them into God's self, thereafter changing God and affecting the rest of the universe throughout time. On the other hand, he sees God as permanent but as deficient in actuality and change: alone, God is merely eternally unrealized possibilities, and requires the world to actualize them. God gives creatures permanence, while the creatures give God actuality and change. Here it is worthwhile to quote Whitehead at length:
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This work has been pioneered by John B. Cobb, Jr., whose book Is It Too Late? A Theology of Ecology (1971) was the first single-authored book in environmental ethics. Cobb also co-authored a book with economist Herman Daly entitled For the Common Good: Redirecting the Economy toward Community, the Environment, and a Sustainable Future (1989), which applied Whitehead's thought to economics, and received the Grawemeyer Award for Ideas Improving World Order. Cobb followed this with a second book, Sustaining the Common Good: A Christian Perspective on the Global Economy (1994), which aimed to challenge "economists' zealous faith in the great god of growth."
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Wieman's words proved prophetic. Though Process and Reality has been called "arguably the most impressive single metaphysical text of the twentieth century," it has been little-read and little-understood, partly because it demands – as Isabelle Stengers puts it – "that its readers accept the adventure of the questions that will separate them from every consensus." Whitehead questioned western philosophy's most dearly held assumptions about how the universe works, but in doing so he managed to anticipate a number of 21st century scientific and philosophical problems and provide novel solutions.
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At the time structures such as Lie algebras and hyperbolic quaternions drew attention to the need to expand algebraic structures beyond the associatively multiplicative class. In a review Alexander Macfarlane wrote: "The main idea of the work is not unification of the several methods, nor generalization of ordinary algebra so as to include them, but rather the comparative study of their several structures." In a separate review, G. B. Mathews wrote, "It possesses a unity of design which is really remarkable, considering the variety of its themes."
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In fact, process theology is difficult to define because process theologians are so diverse and transdisciplinary in their views and interests. John B. Cobb, Jr. is a process theologian who has also written books on biology and economics. Roland Faber and Catherine Keller integrate Whitehead with poststructuralist, postcolonialist, and feminist theory. Charles Birch was both a theologian and a geneticist. Franklin I. Gamwell writes on theology and political theory. In Syntheism - Creating God in The Internet Age, futurologists Alexander Bard and Jan Söderqvist repeatedly credit Whitehead for the process theology they see rising out of the participatory culture expected to dominate the digital era.
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It must be emphasized, however, that an entity is not merely a sum of its relations, but also a valuation of them and reaction to them. For Whitehead, creativity is the absolute principle of existence, and every entity (whether it is a human being, a tree, or an electron) has some degree of novelty in how it responds to other entities, and is not fully determined by causal or mechanistic laws. Of course, most entities do not have consciousness. As a human being's actions cannot always be predicted, the same can be said of where a tree's roots will grow, or how an electron will move, or whether it will rain tomorrow. Moreover, inability to predict an electron's movement (for instance) is not due to faulty understanding or inadequate technology; rather, the fundamental creativity/freedom of all entities means that there will always remain phenomena that are unpredictable.
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In Whitehead's view, then, concepts such as "quality", "matter", and "form" are problematic. These "classical" concepts fail to adequately account for change, and overlook the active and experiential nature of the most basic elements of the world. They are useful abstractions, but are not the world's basic building blocks. What is ordinarily conceived of as a single person, for instance, is philosophically described as a continuum of overlapping events. After all, people change all the time, if only because they have aged by another second and had some further experience. These occasions of experience are logically distinct, but are progressively connected in what Whitehead calls a "society" of events. By assuming that enduring objects are the most real and fundamental things in the universe, materialists have mistaken the abstract for the concrete (what Whitehead calls the "fallacy of misplaced concreteness").
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The ultimate substantive legacy of Principia Mathematica is mixed. It is generally accepted that Kurt Gödel's incompleteness theorem of 1931 definitively demonstrated that for any set of axioms and inference rules proposed to encapsulate mathematics, there would in fact be some truths of mathematics which could not be deduced from them, and hence that Principia Mathematica could never achieve its aims. However, Gödel could not have come to this conclusion without Whitehead and Russell's book. In this way, Principia Mathematica's legacy might be described as its key role in disproving the possibility of achieving its own stated goals. But beyond this somewhat ironic legacy, the book popularized modern mathematical logic and drew important connections between logic, epistemology, and metaphysics.
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In fact, Whitehead describes any entity as in some sense nothing more and nothing less than the sum of its relations to other entities – its synthesis of and reaction to the world around it. A real thing is just that which forces the rest of the universe to in some way conform to it; that is to say, if theoretically a thing made strictly no difference to any other entity (i.e. it was not related to any other entity), it could not be said to really exist. Relations are not secondary to what a thing is, they are what the thing is.
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In 1918 Whitehead's academic responsibilities began to seriously expand as he accepted a number of high administrative positions within the University of London system, of which Imperial College London was a member at the time. He was elected Dean of the Faculty of Science at the University of London in late 1918 (a post he held for four years), a member of the University of London's Senate in 1919, and chairman of the Senate's Academic (leadership) Council in 1920, a post which he held until he departed for America in 1924. Whitehead was able to exert his newfound influence to successfully lobby for a new history of science department, help establish a Bachelor of Science degree (previously only Bachelor of Arts degrees had been offered), and make the school more accessible to less wealthy students.
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Alfred North Whitehead was born in Ramsgate, Kent, England, in 1861. His father, Alfred Whitehead, was a minister and schoolmaster of Chatham House Academy, a successful school for boys established by Thomas Whitehead, Alfred North's grandfather. Whitehead himself recalled both of them as being very successful schoolmasters, but that his grandfather was the more extraordinary man. Whitehead's mother was Maria Sarah Whitehead, formerly Maria Sarah Buckmaster. Whitehead was apparently not particularly close with his mother, as he never mentioned her in any of his writings, and there is evidence that Whitehead's wife, Evelyn, had a low opinion of her.
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It should be emphasized, however, that for Whitehead God is not necessarily tied to religion. Rather than springing primarily from religious faith, Whitehead saw God as necessary for his metaphysical system. His system required that an order exist among possibilities, an order that allowed for novelty in the world and provided an aim to all entities. Whitehead posited that these ordered potentials exist in what he called the primordial nature of God. However, Whitehead was also interested in religious experience. This led him to reflect more intensively on what he saw as the second nature of God, the consequent nature. Whitehead's conception of God as a "dipolar" entity has called for fresh theological thinking.
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Rather than teach small parts of a large number of subjects, Whitehead advocated teaching a relatively few important concepts that the student could organically link to many different areas of knowledge, discovering their application in actual life. For Whitehead, education should be the exact opposite of the multidisciplinary, value-free school model – it should be transdisciplinary, and laden with values and general principles that provide students with a bedrock of wisdom and help them to make connections between areas of knowledge that are usually regarded as separate.
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Early followers of Whitehead were found primarily at the University of Chicago's Divinity School, where Henry Nelson Wieman initiated an interest in Whitehead's work that would last for about thirty years. Professors such as Wieman, Charles Hartshorne, Bernard Loomer, Bernard Meland, and Daniel Day Williams made Whitehead's philosophy arguably the most important intellectual thread running through the Divinity School. They taught generations of Whitehead scholars, the most notable of which is John B. Cobb, Jr.
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Whitehead was unimpressed by this objection. In the notes of one his students for a 1927 class, Whitehead was quoted as saying: "Every scientific man in order to preserve his reputation has to say he dislikes metaphysics. What he means is he dislikes having his metaphysics criticized." In Whitehead's view, scientists and philosophers make metaphysical assumptions about how the universe works all the time, but such assumptions are not easily seen precisely because they remain unexamined and unquestioned. While Whitehead acknowledged that "philosophers can never hope finally to formulate these metaphysical first principles," he argued that people need to continually re-imagine their basic assumptions about how the universe works if philosophy and science are to make any real progress, even if that progress remains permanently asymptotic. For this reason Whitehead regarded metaphysical investigations as essential to both good science and good philosophy.
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In addition to numerous articles on mathematics, Whitehead wrote three major books on the subject: A Treatise on Universal Algebra (1898), Principia Mathematica (co-written with Bertrand Russell and published in three volumes between 1910 and 1913), and An Introduction to Mathematics (1911). The former two books were aimed exclusively at professional mathematicians, while the latter book was intended for a larger audience, covering the history of mathematics and its philosophical foundations. Principia Mathematica in particular is regarded as one of the most important works in mathematical logic of the 20th century.
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For Whitehead the core of religion was individual. While he acknowledged that individuals cannot ever be fully separated from their society, he argued that life is an internal fact for its own sake before it is an external fact relating to others. His most famous remark on religion is that "religion is what the individual does with his own solitariness ... and if you are never solitary, you are never religious." Whitehead saw religion as a system of general truths that transformed a person's character. He took special care to note that while religion is often a good influence, it is not necessarily good – an idea which he called a "dangerous delusion" (e.g., a religion might encourage the violent extermination of a rival religion's adherents).
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However, Mathews' frustration with Whitehead's books did not negatively affect his interest. In fact, there were numerous philosophers and theologians at Chicago's Divinity School that perceived the importance of what Whitehead was doing without fully grasping all of the details and implications. In 1927 they invited one of America's only Whitehead experts – Henry Nelson Wieman – to Chicago to give a lecture explaining Whitehead's thought. Wieman's lecture was so brilliant that he was promptly hired to the faculty and taught there for twenty years, and for at least thirty years afterward Chicago's Divinity School was closely associated with Whitehead's thought.
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Beginning in the late 1910s and early 1920s, Whitehead gradually turned his attention from mathematics to philosophy of science, and finally to metaphysics. He developed a comprehensive metaphysical system which radically departed from most of western philosophy. Whitehead argued that reality consists of processes rather than material objects, and that processes are best defined by their relations with other processes, thus rejecting the theory that reality is fundamentally constructed by bits of matter that exist independently of one another. Today Whitehead's philosophical works – particularly Process and Reality – are regarded as the foundational texts of process philosophy.
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The two volume biography of Whitehead by Victor Lowe is the most definitive presentation of the life of Whitehead. However, many details of Whitehead's life remain obscure because he left no Nachlass; his family carried out his instructions that all of his papers be destroyed after his death. Additionally, Whitehead was known for his "almost fanatical belief in the right to privacy", and for writing very few personal letters of the kind that would help to gain insight on his life. This led to Lowe himself remarking on the first page of Whitehead's biography, "No professional biographer in his right mind would touch him."
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Whitehead also described religion more technically as "an ultimate craving to infuse into the insistent particularity of emotion that non-temporal generality which primarily belongs to conceptual thought alone." In other words, religion takes deeply felt emotions and contextualizes them within a system of general truths about the world, helping people to identify their wider meaning and significance. For Whitehead, religion served as a kind of bridge between philosophy and the emotions and purposes of a particular society. It is the task of religion to make philosophy applicable to the everyday lives of ordinary people.
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Whitehead's most complete work on education is the 1929 book The Aims of Education and Other Essays, which collected numerous essays and addresses by Whitehead on the subject published between 1912 and 1927. The essay from which Aims of Education derived its name was delivered as an address in 1916 when Whitehead was president of the London Branch of the Mathematical Association. In it, he cautioned against the teaching of what he called "inert ideas" – ideas that are disconnected scraps of information, with no application to real life or culture. He opined that "education with inert ideas is not only useless: it is, above all things, harmful."
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But while Claremont remains the most concentrated hub of Whiteheadian activity, the place where Whitehead's thought currently seems to be growing the most quickly is in China. In order to address the challenges of modernization and industrialization, China has begun to blend traditions of Taoism, Buddhism, and Confucianism with Whitehead's "constructive post-modern" philosophy in order to create an "ecological civilization." To date, the Chinese government has encouraged the building of twenty-three university-based centers for the study of Whitehead's philosophy, and books by process philosophers John Cobb and David Ray Griffin are becoming required reading for Chinese graduate students. Cobb has attributed China's interest in process philosophy partly to Whitehead's stress on the mutual interdependence of humanity and nature, as well as his emphasis on an educational system that includes the teaching of values rather than simply bare facts.
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To put it another way, a thing or person is often seen as having a "defining essence" or a "core identity" that is unchanging, and describes what the thing or person really is. In this way of thinking, things and people are seen as fundamentally the same through time, with any changes being qualitative and secondary to their core identity (e.g. "Mark's hair has turned gray as he has gotten older, but he is still the same person"). But in Whitehead's cosmology, the only fundamentally existent things are discrete "occasions of experience" that overlap one another in time and space, and jointly make up the enduring person or thing. On the other hand, what ordinary thinking often regards as "the essence of a thing" or "the identity/core of a person" is an abstract generalization of what is regarded as that person or thing's most important or salient features across time. Identities do not define people, people define identities. Everything changes from moment to moment, and to think of anything as having an "enduring essence" misses the fact that "all things flow", though it is often a useful way of speaking.
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A second problem with materialism is that it obscures the importance of relations. It sees every object as distinct and discrete from all other objects. Each object is simply an inert clump of matter that is only externally related to other things. The idea of matter as primary makes people think of objects as being fundamentally separate in time and space, and not necessarily related to anything. But in Whitehead's view, relations take a primary role, perhaps even more important than the relata themselves. A student taking notes in one of Whitehead's fall 1924 classes wrote that:
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Whitehead describes causal efficacy as "the experience dominating the primitive living organisms, which have a sense for the fate from which they have emerged, and the fate towards which they go." It is, in other words, the sense of causal relations between entities, a feeling of being influenced and affected by the surrounding environment, unmediated by the senses. Presentational immediacy, on the other hand, is what is usually referred to as "pure sense perception", unmediated by any causal or symbolic interpretation, even unconscious interpretation. In other words, it is pure appearance, which may or may not be delusive (e.g. mistaking an image in a mirror for "the real thing").
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Whitehead and Russell had thought originally that Principia Mathematica would take a year to complete; it ended up taking them ten years. To add insult to injury, when it came time for publication, the three-volume work was so massive (more than 2,000 pages) and its audience so narrow (professional mathematicians) that it was initially published at a loss of 600 pounds, 300 of which was paid by Cambridge University Press, 200 by the Royal Society of London, and 50 apiece by Whitehead and Russell themselves. Despite the initial loss, today there is likely no major academic library in the world which does not hold a copy of Principia Mathematica.
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In physics, Whitehead's thought has had some influence. He articulated a view that might perhaps be regarded as dual to Einstein's general relativity, see Whitehead's theory of gravitation. It has been severely criticized. Yutaka Tanaka, who suggests that the gravitational constant disagrees with experimental findings, proposes that Einstein's work does not actually refute Whitehead's formulation. Whitehead's view has now been rendered obsolete, with the discovery of gravitational waves. They are phenonena observed locally that largely violate the kind of local flatness of space that Whitehead assumes. Consequently, Whitehead's cosmology must be regarded as a local approximation, and his assumption of a uniform spatio-temporal geometry, Minkowskian in particular, as an often-locally-adequate approximation. An exact replacement of Whitehead's cosmology would need to admit a Riemannian geometry. Also, although Whitehead himself gave only secondary consideration to quantum theory, his metaphysics of processes has proved attractive to some physicists in that field. Henry Stapp and David Bohm are among those whose work has been influenced by Whitehead.
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This is not to say that Whitehead's thought was widely accepted or even well-understood. His philosophical work is generally considered to be among the most difficult to understand in all of the western canon. Even professional philosophers struggled to follow Whitehead's writings. One famous story illustrating the level of difficulty of Whitehead's philosophy centers around the delivery of Whitehead's Gifford lectures in 1927–28 – following Arthur Eddington's lectures of the year previous – which Whitehead would later publish as Process and Reality:
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However, while Whitehead saw religion as beginning in solitariness, he also saw religion as necessarily expanding beyond the individual. In keeping with his process metaphysics in which relations are primary, he wrote that religion necessitates the realization of "the value of the objective world which is a community derivative from the interrelations of its component individuals." In other words, the universe is a community which makes itself whole through the relatedness of each individual entity to all the others – meaning and value do not exist for the individual alone, but only in the context of the universal community. Whitehead writes further that each entity "can find no such value till it has merged its individual claim with that of the objective universe. Religion is world-loyalty. The spirit at once surrenders itself to this universal claim and appropriates it for itself." In this way the individual and universal/social aspects of religion are mutually dependent.
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God's consequent nature, on the other hand, is anything but unchanging – it is God's reception of the world's activity. As Whitehead puts it, "[God] saves the world as it passes into the immediacy of his own life. It is the judgment of a tenderness which loses nothing that can be saved." In other words, God saves and cherishes all experiences forever, and those experiences go on to change the way God interacts with the world. In this way, God is really changed by what happens in the world and the wider universe, lending the actions of finite creatures an eternal significance.
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Antibiotics revolutionized medicine in the 20th century, and have together with vaccination led to the near eradication of diseases such as tuberculosis in the developed world. Their effectiveness and easy access led to overuse, especially in livestock raising, prompting bacteria to develop resistance. This has led to widespread problems with antimicrobial and antibiotic resistance, so much as to prompt the World Health Organization to classify antimicrobial resistance as a "serious threat [that] is no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country".
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Antibacterial antibiotics are commonly classified based on their mechanism of action, chemical structure, or spectrum of activity. Most target bacterial functions or growth processes. Those that target the bacterial cell wall (penicillins and cephalosporins) or the cell membrane (polymyxins), or interfere with essential bacterial enzymes (rifamycins, lipiarmycins, quinolones, and sulfonamides) have bactericidal activities. Those that target protein synthesis (macrolides, lincosamides and tetracyclines) are usually bacteriostatic (with the exception of bactericidal aminoglycosides). Further categorization is based on their target specificity. "Narrow-spectrum" antibacterial antibiotics target specific types of bacteria, such as Gram-negative or Gram-positive bacteria, whereas broad-spectrum antibiotics affect a wide range of bacteria. Following a 40-year hiatus in discovering new classes of antibacterial compounds, four new classes of antibacterial antibiotics have been brought into clinical use in the late 2000s and early 2010s: cyclic lipopeptides (such as daptomycin), glycylcyclines (such as tigecycline), oxazolidinones (such as linezolid), and lipiarmycins (such as fidaxomicin).
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Interactions between alcohol and certain antibiotics may occur and may cause side-effects and decreased effectiveness of antibiotic therapy. While moderate alcohol consumption is unlikely to interfere with many common antibiotics, there are specific types of antibiotics with which alcohol consumption may cause serious side-effects. Therefore, potential risks of side-effects and effectiveness depend on the type of antibiotic administered. Despite the lack of a categorical counterindication, the belief that alcohol and antibiotics should never be mixed is widespread.
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In 1939, coinciding with the start of World War II, Rene Dubos reported the discovery of the first naturally derived antibiotic, tyrothricin, a compound of 20% gramicidin and 80% tyrocidine, from B. brevis. It was one of the first commercially manufactured antibiotics universally and was very effective in treating wounds and ulcers during World War II. Gramicidin, however, could not be used systemically because of toxicity. Tyrocidine also proved too toxic for systemic usage. Research results obtained during that period were not shared between the Axis and the Allied powers during the war.
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The successful outcome of antimicrobial therapy with antibacterial compounds depends on several factors. These include host defense mechanisms, the location of infection, and the pharmacokinetic and pharmacodynamic properties of the antibacterial. A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. These findings are based on laboratory studies, and in clinical settings have also been shown to eliminate bacterial infection. Since the activity of antibacterials depends frequently on its concentration, in vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.
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There has been extensive use of antibiotics in animal husbandry. In the United States, the question of emergence of antibiotic-resistant bacterial strains due to use of antibiotics in livestock was raised by the US Food and Drug Administration (FDA) in 1977. In March 2012, the United States District Court for the Southern District of New York, ruling in an action brought by the Natural Resources Defense Council and others, ordered the FDA to revoke approvals for the use of antibiotics in livestock, which violated FDA regulations.
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In empirical therapy, a patient has proven or suspected infection, but the responsible microorganism is not yet unidentified. While the microorgainsim is being identified the doctor will usually administer the best choice of antibiotic that will be most active against the likely cause of infection usually a broad spectrum antibiotic. Empirical therapy is usually initiated before the doctor knows the exact identification of microorgansim causing the infection as the identification process make take several days in the laboratory.
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Antibiotics are screened for any negative effects on humans or other mammals before approval for clinical use, and are usually considered safe and most are well tolerated. However, some antibiotics have been associated with a range of adverse side effects. Side-effects range from mild to very serious depending on the antibiotics used, the microbial organisms targeted, and the individual patient. Side effects may reflect the pharmacological or toxicological properties of the antibiotic or may involve hypersensitivity reactions or anaphylaxis. Safety profiles of newer drugs are often not as well established as for those that have a long history of use. Adverse effects range from fever and nausea to major allergic reactions, including photodermatitis and anaphylaxis. Common side-effects include diarrhea, resulting from disruption of the species composition in the intestinal flora, resulting, for example, in overgrowth of pathogenic bacteria, such as Clostridium difficile. Antibacterials can also affect the vaginal flora, and may lead to overgrowth of yeast species of the genus Candida in the vulvo-vaginal area. Additional side-effects can result from interaction with other drugs, such as elevated risk of tendon damage from administration of a quinolone antibiotic with a systemic corticosteroid. Some scientists have hypothesized that the indiscriminate use of antibiotics alter the host microbiota and this has been associated with chronic disease.
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The majority of studies indicate antibiotics do interfere with contraceptive pills, such as clinical studies that suggest the failure rate of contraceptive pills caused by antibiotics is very low (about 1%). In cases where antibacterials have been suggested to affect the efficiency of birth control pills, such as for the broad-spectrum antibacterial rifampicin, these cases may be due to an increase in the activities of hepatic liver enzymes' causing increased breakdown of the pill's active ingredients. Effects on the intestinal flora, which might result in reduced absorption of estrogens in the colon, have also been suggested, but such suggestions have been inconclusive and controversial. Clinicians have recommended that extra contraceptive measures be applied during therapies using antibacterials that are suspected to interact with oral contraceptives.
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The emergence of antibiotic resistance has prompted restrictions on their use in the UK in 1970 (Swann report 1969), and the EU has banned the use of antibiotics as growth-promotional agents since 2003. Moreover, several organizations (e.g., The American Society for Microbiology (ASM), American Public Health Association (APHA) and the American Medical Association (AMA)) have called for restrictions on antibiotic use in food animal production and an end to all nontherapeutic uses.[citation needed] However, commonly there are delays in regulatory and legislative actions to limit the use of antibiotics, attributable partly to resistance against such regulation by industries using or selling antibiotics, and to the time required for research to test causal links between their use and resistance to them. Two federal bills (S.742 and H.R. 2562) aimed at phasing out nontherapeutic use of antibiotics in US food animals were proposed, but have not passed. These bills were endorsed by public health and medical organizations, including the American Holistic Nurses' Association, the American Medical Association, and the American Public Health Association (APHA).
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The effects of some types of mold on infection had been noticed many times over the course of history (see: History of penicillin). In 1928, Alexander Fleming noticed the same effect in a Petri dish, where a number of disease-causing bacteria were killed by a fungus of the genus Penicillium. Fleming postulated that the effect is mediated by an antibacterial compound he named penicillin, and that its antibacterial properties could be exploited for chemotherapy. He initially characterized some of its biological properties, and attempted to use a crude preparation to treat some infections, but he was unable to pursue its further development without the aid of trained chemists.
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In April 2013, the Infectious Disease Society of America (IDSA) reported that the weak antibiotic pipeline does not match bacteria's increasing ability to develop resistance. Since 2009, only 2 new antibiotics were approved in the United States. The number of new antibiotics approved for marketing per year declines continuously. The report identified seven antibiotics against the Gram-negative bacilli (GNB) currently in phase 2 or phase 3 clinical trials. However, these drugs do not address the entire spectrum of resistance of GNB. Some of these antibiotics are combination of existent treatments:
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Vaccines rely on immune modulation or augmentation. Vaccination either excites or reinforces the immune competence of a host to ward off infection, leading to the activation of macrophages, the production of antibodies, inflammation, and other classic immune reactions. Antibacterial vaccines have been responsible for a drastic reduction in global bacterial diseases. Vaccines made from attenuated whole cells or lysates have been replaced largely by less reactogenic, cell-free vaccines consisting of purified components, including capsular polysaccharides and their conjugates, to protein carriers, as well as inactivated toxins (toxoids) and proteins.
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Antibiotics
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8,448
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The emergence of resistance of bacteria to antibiotics is a common phenomenon. Emergence of resistance often reflects evolutionary processes that take place during antibiotic therapy. The antibiotic treatment may select for bacterial strains with physiologically or genetically enhanced capacity to survive high doses of antibiotics. Under certain conditions, it may result in preferential growth of resistant bacteria, while growth of susceptible bacteria is inhibited by the drug. For example, antibacterial selection for strains having previously acquired antibacterial-resistance genes was demonstrated in 1943 by the Luria–Delbrück experiment. Antibiotics such as penicillin and erythromycin, which used to have a high efficacy against many bacterial species and strains, have become less effective, due to the increased resistance of many bacterial strains.
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Antibiotics
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8,449
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Several organizations concerned with antimicrobial resistance are lobbying to eliminate the unnecessary use of antibiotics. The issues of misuse and overuse of antibiotics have been addressed by the formation of the US Interagency Task Force on Antimicrobial Resistance. This task force aims to actively address antimicrobial resistance, and is coordinated by the US Centers for Disease Control and Prevention, the Food and Drug Administration (FDA), and the National Institutes of Health (NIH), as well as other US agencies. An NGO campaign group is Keep Antibiotics Working. In France, an "Antibiotics are not automatic" government campaign started in 2002 and led to a marked reduction of unnecessary antibiotic prescriptions, especially in children.
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Antibiotics
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8,450
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The first sulfonamide and first commercially available antibacterial, Prontosil, was developed by a research team led by Gerhard Domagk in 1932 at the Bayer Laboratories of the IG Farben conglomerate in Germany. Domagk received the 1939 Nobel Prize for Medicine for his efforts. Prontosil had a relatively broad effect against Gram-positive cocci, but not against enterobacteria. Research was stimulated apace by its success. The discovery and development of this sulfonamide drug opened the era of antibacterials.
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Antibiotics
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8,451
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Exposure to antibiotics early in life is associated with increased body mass in humans and mouse models. Early life is a critical period for the establishment of the intestinal microbiota and for metabolic development. Mice exposed to subtherapeutic antibiotic treatment (STAT)– with either penicillin, vancomycin, penicillin and vancomycin, or chlortetracycline had altered composition of the gut microbiota as well as its metabolic capabilities. Moreover, research have shown that mice given low-dose penicillin (1 μg/g body weight) around birth and throughout the weaning process had an increased body mass and fat mass, accelerated growth, and increased hepatic expression of genes involved in adipogenesis, compared to controlled mice. In addition, penicillin in combination with a high-fat diet increased fasting insulin levels in mice. However, it is unclear whether or not antibiotics cause obesity in humans. Studies have found a correlation between early exposure of antibiotics (<6 months) and increased body mass (at 10 and 20 months). Another study found that the type of antibiotic exposure was also significant with the highest risk of being overweight in those given macrolides compared to penicillin and cephalosporin. Therefore, there is correlation between antibiotic exposure in early life and obesity in humans, but whether or not there is a causal relationship remains unclear. Although there is a correlation between antibiotic use in early life and obesity, the effect of antibiotics on obesity in humans needs to be weighed against the beneficial effects of clinically indicated treatment with antibiotics in infancy.
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Antibiotics
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8,452
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Common forms of antibiotic misuse include excessive use of prophylactic antibiotics in travelers and failure of medical professionals to prescribe the correct dosage of antibiotics on the basis of the patient's weight and history of prior use. Other forms of misuse include failure to take the entire prescribed course of the antibiotic, incorrect dosage and administration, or failure to rest for sufficient recovery. Inappropriate antibiotic treatment, for example, is their prescription to treat viral infections such as the common cold. One study on respiratory tract infections found "physicians were more likely to prescribe antibiotics to patients who appeared to expect them". Multifactorial interventions aimed at both physicians and patients can reduce inappropriate prescription of antibiotics.
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Antibiotics
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8,453
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Windows 8 introduced major changes to the operating system's platform and user interface to improve its user experience on tablets, where Windows was now competing with mobile operating systems, including Android and iOS. In particular, these changes included a touch-optimized Windows shell based on Microsoft's "Metro" design language, the Start screen (which displays programs and dynamically updated content on a grid of tiles), a new platform for developing apps with an emphasis on touchscreen input, integration with online services (including the ability to sync apps and settings between devices), and Windows Store, an online store for downloading and purchasing new software. Windows 8 added support for USB 3.0, Advanced Format hard drives, near field communications, and cloud computing. Additional security features were introduced, such as built-in antivirus software, integration with Microsoft SmartScreen phishing filtering service and support for UEFI Secure Boot on supported devices with UEFI firmware, to prevent malware from infecting the boot process.
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Windows_8
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8,454
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Exceptions to the restrictions faced by Windows Store apps are given to web browsers. The user's default browser can distribute a Metro-style web browser in same package as the desktop version, which has access to functionality unavailable to other apps, such as being able to permanently run in the background, use multiple background processes, and use Windows API code instead of WinRT (allowing for code to be re-used with the desktop version, while still taking advantage of features available to Windows Store apps, such as charms). Microsoft advertises this exception privilege "New experience enabled" (formerly "Metro-style enabled").
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Windows_8
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8,455
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Retail distribution of Windows 8 has since been discontinued in favor of Windows 8.1. Unlike 8, 8.1 is available as "full version software" at both retail and online for download that does not require a previous version of Windows in order to be installed. Pricing for these new copies remain identical. With the retail release returning to full version software for Windows 8.1, the "Personal Use License" exemption was removed from the OEM SKU, meaning that end users building their own PCs for personal use must use the full retail version in order to satisfy the Windows 8.1 licensing requirements. Windows 8.1 with Bing is a special OEM-specific SKU of Windows 8.1 subsidized by Microsoft's Bing search engine.
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Windows_8
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8,456
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Task Manager has been redesigned, including a new processes tab with the option to display fewer or more details of running applications and background processes, a heat map using different colors indicating the level of resource usage, network and disk counters, grouping by process type (e.g. applications, background processes and Windows processes), friendly names for processes and a new option which allows users to search the web to find information about obscure processes. Additionally, the Blue Screen of Death has been updated with a simpler and modern design with less technical information displayed.
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Windows_8
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8,457
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In June 2014, state broadcaster China Central Television (CCTV) broadcast a news story further characterizing Windows 8 as a threat to national security. The story featured an interview with Ni Guangnan, who stated that operating systems could aggregate "sensitive user information" that could be used to "understand the conditions and activities of our national economy and society", and alleged that per documents leaked by Edward Snowden, the U.S. government had worked with Microsoft to retrieve encrypted information. Yang Min, a computer scientist at Fudan University, also stated that "the security features of Windows 8 are basically to the benefit of Microsoft, allowing them control of the users' data, and that poses a big challenge to the national strategy for information security." Microsoft denied the claims in a number of posts on the Chinese social network Sina Weibo, which stated that the company had never "assisted any government in an attack of another government or clients" or provided client data to the U.S. government, never "provided any government the authority to directly visit" or placed any backdoors in its products and services, and that it had never concealed government requests for client data.
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Windows_8
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8,458
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The term "Immersive app" had been used internally by Microsoft developers to refer to the apps prior to the first official presentation of Windows 8, after which they were referred to as "Metro-style apps" in reference to the Metro design language. The term was phased out in August 2012; a Microsoft spokesperson denied rumors that the change was related to a potential trademark issue, and stated that "Metro" was only a codename that would be replaced prior to Windows 8's release. Following these reports, the terms "Modern UI-style apps", "Windows 8-style apps" and "Windows Store apps" began to be used by various Microsoft documents and material to refer to the new apps. In an interview on September 12, 2012, Soma Somasegar (vice president of Microsoft's development software division) confirmed that "Windows Store apps" would be the official term for the apps. An MSDN page explaining the Metro design language uses the term "Modern design" to refer to the language as a whole.
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Windows_8
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8,459
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A vertical toolbar known as the charms (accessed by swiping from the right edge of a touchscreen, or pointing the cursor at hotspots in the right corners of a screen) provides access to system and app-related functions, such as search, sharing, device management, settings, and a Start button. The traditional desktop environment for running desktop applications is accessed via a tile on the Start screen. The Start button on the taskbar from previous versions of Windows has been converted into a hotspot in the lower-left corner of the screen, which displays a large tooltip displaying a thumbnail of the Start screen. Swiping from the left edge of a touchscreen or clicking in the top-left corner of the screen allows one to switch between apps and Desktop. Pointing the cursor in the top-left corner of the screen and moving down reveals a thumbnail list of active apps. Aside from the removal of the Start button and the replacement of the Aero Glass theme with a flatter and solid-colored design, the desktop interface on Windows 8 is similar to that of Windows 7.
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Windows_8
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8,460
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Windows 8 supports a feature of the UEFI specification known as "Secure boot", which uses a public-key infrastructure to verify the integrity of the operating system and prevent unauthorized programs such as bootkits from infecting the device's boot process. Some pre-built devices may be described as "certified" by Microsoft; these must have secure boot enabled by default, and provide ways for users to disable or re-configure the feature. ARM-based Windows RT devices must have secure boot permanently enabled.
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Windows_8
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8,461
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Windows 8 was distributed as a retail box product on DVD, and through a digital download that could be converted into DVD or USB install media. As part of a launch promotion, Microsoft offered Windows 8 Pro upgrades at a discounted price of US$39.99 online, or $69.99 for retail box from its launch until January 31, 2013; afterward the Windows 8 price has been $119.99 and the Pro price $199.99. Those who purchased new PCs pre-loaded with Windows 7 Home Basic, Home Premium, Professional, or Ultimate between June 2, 2012 and January 31, 2013 could digitally purchase a Windows 8 Pro upgrade for US$14.99. Several PC manufacturers offered rebates and refunds on Windows 8 upgrades obtained through the promotion on select models, such as Hewlett-Packard (in the U.S. and Canada on select models), and Acer (in Europe on selected Ultrabook models). During these promotions, the Windows Media Center add-on for Windows 8 Pro was also offered for free.
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Windows_8
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8,462
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Internet Explorer 10 is included as both a desktop program and a touch-optimized app, and includes increased support for HTML5, CSS3, and hardware acceleration. The Internet Explorer app does not support plugins or ActiveX components, but includes a version of Adobe Flash Player that is optimized for touch and low power usage. Initially, Adobe Flash would only work on sites included on a "Compatibility View" whitelist; however, after feedback from users and additional compatibility tests, an update in March 2013 changed this behavior to use a smaller blacklist of sites with known compatibility issues instead, allowing Flash to be used on most sites by default. The desktop version does not contain these limitations.
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Windows_8
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8,463
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Microsoft began an advertising campaign centered around Windows 8 and its Surface tablet in October 2012, starting with its first television advertisement premiering on October 14, 2012. Microsoft's advertising budget of US$1.5–1.8 billion was significantly larger than the US$200 million campaign used to promote Windows 95. As part of its campaign, Microsoft set up 34 pop-up stores inside malls (primarily focusing on Surface), provided training for retail employees in partnership with Intel, and collaborated with the electronics store chain Best Buy to design expanded spaces to showcase devices. In an effort to make retail displays of Windows 8 devices more "personal", Microsoft also developed a character known in English-speaking markets as "Allison Brown", whose fictional profile (including personal photos, contacts, and emails) is also featured on demonstration units of Windows 8 devices.
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Windows_8
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8,464
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Windows 8 provides heavier integration with online services from Microsoft and others. A user can now log in to Windows with a Microsoft account, which can be used to access services and synchronize applications and settings between devices. Windows 8 also ships with a client app for Microsoft's SkyDrive cloud storage service, which also allows apps to save files directly to SkyDrive. A SkyDrive client for the desktop and File Explorer is not included in Windows 8, and must be downloaded separately. Bundled multimedia apps are provided under the Xbox brand, including Xbox Music, Xbox Video, and the Xbox SmartGlass companion for use with an Xbox 360 console. Games can integrate into an Xbox Live hub app, which also allows users to view their profile and gamerscore. Other bundled apps provide the ability to link Flickr and Facebook. Due to Facebook Connect service changes, Facebook support is disabled in all bundled apps effective June 8, 2015.
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Windows_8
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8,465
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Windows Explorer, which has been renamed File Explorer, now includes a ribbon in place of the command bar. File operation dialog boxes have been updated to provide more detailed statistics, the ability to pause file transfers, and improvements in the ability to manage conflicts when copying files. A new "File History" function allows incremental revisions of files to be backed up to and restored from a secondary storage device, while Storage Spaces allows users to combine different sized hard disks into virtual drives and specify mirroring, parity, or no redundancy on a folder-by-folder basis.
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Windows_8
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8,466
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Many other builds were released until the Japan's Developers Day conference, when Steven Sinofsky announced that Windows 8 Release Preview (build 8400) would be released during the first week of June. On May 28, 2012, Windows 8 Release Preview (Standard Simplified Chinese x64 edition, not China-specific version, build 8400) was leaked online on various Chinese and BitTorrent websites. On May 31, 2012, Windows 8 Release Preview was released to the public by Microsoft. Major items in the Release Preview included the addition of Sports, Travel, and News apps, along with an integrated version of Adobe Flash Player in Internet Explorer. Like the Developer Preview and the Consumer Preview, the release preview expired on January 15, 2013.
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Windows_8
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8,467
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On August 1, 2012, Windows 8 (build 9200) was released to manufacturing with the build number 6.2.9200.16384 . Microsoft planned to hold a launch event on October 25, 2012 and release Windows 8 for general availability on the next day. However, only a day after its release to manufacturing, a copy of the final version of Windows 8 Enterprise N (a version for European markets lacking bundled media players to comply with a court ruling) leaked online, followed by leaks of the final versions of Windows 8 Pro and Enterprise a few days later. On August 15, 2012, Windows 8 was made available to download for MSDN and TechNet subscribers. Windows 8 was made available to Software Assurance customers on August 16, 2012. Windows 8 was made available for students with a DreamSpark Premium subscription on August 22, 2012, earlier than advertised.
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Windows_8
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8,468
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Windows RT, the only edition of Windows 8 for systems with ARM processors, only supports applications included with the system (such as a special version of Office 2013), supplied through Windows Update, or Windows Store apps, to ensure that the system only runs applications that are optimized for the architecture. Windows RT does not support running IA-32 or x64 applications. Windows Store apps can either support both the x86 and ARM architectures, or compiled to support a specific architecture.
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Windows_8
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8,469
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Several notable video game developers criticized Microsoft for making its Windows Store a closed platform subject to its own regulations, as it conflicted with their view of the PC as an open platform. Markus "Notch" Persson (creator of the indie game Minecraft), Gabe Newell (co-founder of Valve Corporation and developer of software distribution platform Steam), and Rob Pardo from Activision Blizzard voiced concern about the closed nature of the Windows Store. However, Tom Warren of The Verge stated that Microsoft's addition of the Store was simply responding to the success of both Apple and Google in pursuing the "curated application store approach."
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Windows_8
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8,470
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Windows 8 is available in three different editions, of which the lowest version, branded simply as Windows 8, and Windows 8 Pro, were sold at retail in most countries, and as pre-loaded software on new computers. Each edition of Windows 8 includes all of the capabilities and features of the edition below it, and add additional features oriented towards their market segments. For example, Pro added BitLocker, Hyper-V, the ability to join a domain, and the ability to install Windows Media Center as a paid add-on. Users of Windows 8 can purchase a "Pro Pack" license that upgrades their system to Windows 8 Pro through Add features to Windows. This license also includes Windows Media Center. Windows 8 Enterprise contains additional features aimed towards business environments, and is only available through volume licensing. A port of Windows 8 for ARM architecture, Windows RT, is marketed as an edition of Windows 8, but was only included as pre-loaded software on devices specifically developed for it.
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Windows_8
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8,471
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The upgrade addressed a number of criticisms faced by Windows 8 upon its release, with additional customization options for the Start screen, the restoration of a visible Start button on the desktop, the ability to snap up to four apps on a single display, and the ability to boot to the desktop instead of the Start screen. Windows 8's stock apps were also updated, a new Bing-based unified search system was added, SkyDrive was given deeper integration with the operating system, and a number of new stock apps, along with a tutorial, were added. Windows 8.1 also added support for 3D printing, Miracast media streaming, NFC printing, and Wi-Fi Direct.
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Windows_8
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8,472
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Windows Store apps run within a new set of APIs known as Windows Runtime, which supports programming languages such as C, C++, Visual Basic .NET, C#, along with HTML5 and JavaScript. If written in some "high-level" languages, apps written for Windows Runtime can be compatible with both Intel and ARM versions of Windows, otherwise they are not binary code compatible. Components may be compiled as Windows Runtime Components, permitting consumption by all compatible languages. To ensure stability and security, apps run within a sandboxed environment, and require permissions to access certain functionality, such as accessing the Internet or a camera.
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Windows_8
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8,473
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Windows 8 development started before Windows 7 had shipped in 2009. At the Consumer Electronics Show in January 2011, it was announced that the next version of Windows would add support for ARM system-on-chips alongside the existing x86 processors produced by vendors, especially AMD and Intel. Windows division president Steven Sinofsky demonstrated an early build of the port on prototype devices, while Microsoft CEO Steve Ballmer announced the company's goal for Windows to be "everywhere on every kind of device without compromise." Details also began to surface about a new application framework for Windows 8 codenamed "Jupiter", which would be used to make "immersive" applications using XAML (similarly to Windows Phone and Silverlight) that could be distributed via a new packaging system and a rumored application store.
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Windows_8
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8,474
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Three milestone releases of Windows 8 leaked to the general public. Milestone 1, Build 7850, was leaked on April 12, 2011. It was the first build where the text of a window was written centered instead of aligned to the left. It was also probably the first appearance of the Metro-style font, and its wallpaper had the text shhh... let's not leak our hard work. However, its detailed build number reveals that the build was created on September 22, 2010. The leaked copy edition was Enterprise edition. The OS still reads as "Windows 7". Milestone 2, Build 7955, was leaked on April 25, 2011. The traditional Blue Screen of Death (BSoD) was replaced by a new Black screen, although this was later scrapped. This build introduced a new ribbon in Windows Explorer. Build 7959, with minor changes but the first 64-bit version, was leaked on May 1, 2011. The "Windows 7" logo was temporarily replaced with text displaying "Microsoft Confidential". On June 17, 2011, build 7989 64-bit edition was leaked. It introduced a new boot screen featuring the same fish as the default Windows 7 Beta wallpaper, which was later scrapped, and the circling dots as featured in the final (although the final version comes with smaller circling dots throbber). It also had the text Welcome below them, although this was also scrapped.
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Windows_8
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8,475
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Relatively few changes were made from the Release Preview to the final version; these included updated versions of its pre-loaded apps, the renaming of Windows Explorer to File Explorer, the replacement of the Aero Glass theme from Windows Vista and 7 with a new flat and solid-colored theme, and the addition of new background options for the Start screen, lock screen, and desktop. Prior to its general availability on October 26, 2012, updates were released for some of Windows 8's bundled apps, and a "General Availability Cumulative Update" (which included fixes to improve performance, compatibility, and battery life) was released on Tuesday, October 9, 2012. Microsoft indicated that due to improvements to its testing infrastructure, general improvements of this nature are to be released more frequently through Windows Update instead of being relegated to OEMs and service packs only.
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Windows_8
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8,476
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In March 2013, Microsoft also amended its certification requirements to allow tablets to use the 1024×768 resolution as a minimum; this change is expected to allow the production of certified Windows 8 tablets in smaller form factors—a market which is currently dominated by Android-based tablets. Despite the reaction of industry experts, Microsoft reported that they had sold 100 million licenses in the first six months. This matched sales of Windows 7 over a similar period. This statistic includes shipments to channel warehouses which now need to be sold in order to make way for new shipments.
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Windows_8
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8,477
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In May 2013, Microsoft launched a new television campaign for Windows 8 illustrating the capabilities and pricing of Windows 8 tablets in comparison to the iPad, which featured the voice of Siri remarking on the iPad's limitations in a parody of Apple's "Get a Mac" advertisements. On June 12, 2013 during game 1 of the 2013 Stanley Cup Finals, Microsoft premiered the first ad in its "Windows Everywhere" campaign, which promoted Windows 8, Windows Phone 8, and the company's suite of online services as an interconnected platform.
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Windows_8
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8,478
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New features and functionality in Windows 8 include a faster startup through UEFI integration and the new "Hybrid Boot" mode (which hibernates the Windows kernel on shutdown to speed up the subsequent boot), a new lock screen with a clock and notifications, and the ability for enterprise users to create live USB versions of Windows (known as Windows To Go). Windows 8 also adds native support for USB 3.0 devices, which allow for faster data transfers and improved power management with compatible devices, and hard disk 4KB Advanced Format support, as well as support for near field communication to facilitate sharing and communication between devices.
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Windows_8
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8,479
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The interface of Windows 8 has been the subject of mixed reaction. Bright wrote that its system of hot corners and edge swiping "wasn't very obvious" due to the lack of instructions provided by the operating system on the functions accessed through the user interface, even by the video tutorial added on the RTM release (which only instructed users to point at corners of the screen or swipe from its sides). Despite this "stumbling block", Bright said that Windows 8's interface worked well in some places, but began to feel incoherent when switching between the "Metro" and desktop environments, sometimes through inconsistent means. Tom Warren of The Verge wrote that the new interface was "as stunning as it is surprising", contributing to an "incredibly personal" experience once it is customized by the user, but had a steep learning curve, and was awkward to use with a keyboard and mouse. He noted that while forcing all users to use the new touch-oriented interface was a risky move for Microsoft as a whole, it was necessary in order to push development of apps for the Windows Store. Others, such as Adrian Kingsley-Hughes from ZDNet, considered the interface to be "clumsy and impractical" due to its inconsistent design (going as far as considering it "two operating systems unceremoniously bolted together"), and concluded that "Windows 8 wasn't born out of a need or demand; it was born out of a desire on Microsoft's part to exert its will on the PC industry and decide to shape it in a direction—touch and tablets -- that allows it to compete against, and remain relevant in the face of Apple's iPad."
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Windows_8
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8,480
|
Backup and Restore, the backup component of Windows, is deprecated. It still ships with Windows 8 and continues to work on preset schedules, but is pushed to the background and can only be accessed through a Control Panel applet called "Windows 7 File Recovery".:76 Shadow Copy, a component of Windows Explorer that once saved previous versions of changed files, no longer protects local files and folders. It can only access previous versions of shared files stored on a Windows Server computer.:74 The subsystem on which these components worked, however, is still available for other software to use.:74
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Windows_8
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8,481
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Retail versions of Windows 8 are only able to install these apps through Windows Store—a namesake distribution platform which offers both apps, and listings for desktop programs certified for comparability with Windows 8. A method to sideload apps from outside Windows Store is available to devices running Windows 8 Enterprise and joined to a domain; Windows 8 Pro and Windows RT devices that are not part of a domain can also sideload apps, but only after special product keys are obtained through volume licensing.
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Windows_8
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8,482
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Reviews of the various editions of Windows 8 have been mixed. Tom Warren of The Verge said that although Windows 8's emphasis on touch computing was significant and risked alienating desktop users, a "tablet PC with Windows 8 makes an iPad feel immediately out of date" due to the capabilities of the operating system's hybrid model and increased focus on cloud services. David Pierce of The Verge described Windows 8 as "the first desktop operating system that understands what a computer is supposed to do in 2012" and praised Microsoft's "no compromise" approach and the operating system's emphasis on Internet connectivity and cloud services. Pierce also considered the Start Screen to be a "brilliant innovation for desktop computers" when compared with "folder-littered desktops on every other OS" because it allows users to interact with dynamic information. In contrast, an ExtremeTech article said it was Microsoft "flailing" and a review in PC Magazine condemned the Metro-style user interface. Some of the included apps in Windows 8 were considered to be basic and lacking in functionality, but the Xbox apps were praised for their promotion of a multi-platform entertainment experience. Other improvements and features (such as File History, Storage Spaces, and the updated Task Manager) were also regarded as positive changes. Peter Bright of Ars Technica wrote that while its user interface changes may overshadow them, Windows 8's improved performance, updated file manager, new storage functionality, expanded security features, and updated Task Manager were still positive improvements for the operating system. Bright also said that Windows 8's duality towards tablets and traditional PCs was an "extremely ambitious" aspect of the platform as well, but criticized Microsoft for emulating Apple's model of a closed distribution platform when implementing the Windows Store.
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Windows_8
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8,483
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Microsoft released minimum hardware requirements for tablet and laplet devices to be "certified" for Windows 8, and defined a convertible form factor as a standalone device that combines the PC, display and rechargeable power source with a mechanically attached keyboard and pointing device in a single chassis. A convertible can be transformed into a tablet where the attached input devices are hidden or removed leaving the display as the only input mechanism. On March 12, 2013, Microsoft amended its certification requirements to only require that screens on tablets have a minimum resolution of 1024×768 (down from the previous 1366×768). The amended requirement is intended to allow "greater design flexibility" for future products.
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Windows_8
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8,484
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In May 2014, the Government of China banned the internal purchase of Windows 8-based products under government contracts requiring "energy-efficient" devices. The Xinhua News Agency claimed that Windows 8 was being banned in protest of Microsoft's support lifecycle policy and the end of support for Windows XP (which, as of January 2014, had a market share of 49% in China), as the government "obviously cannot ignore the risks of running OS [sic] without guaranteed technical support." However, Ni Guangnan of the Chinese Academy of Sciences had also previously warned that Windows 8 could allegedly expose users to surveillance by the United States government due to its heavy use of internet-based services.
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Windows_8
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8,485
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The three desktop editions of Windows 8 support 32-bit and 64-bit architectures; retail copies of Windows 8 include install DVDs for both architectures, while the online installer automatically installs the version corresponding with the architecture of the system's existing Windows installation. The 32-bit version runs on CPUs compatible with x86 architecture 3rd generation (known as IA-32) or newer, and can run 32-bit and 16-bit applications, although 16-bit support must be enabled first. (16-bit applications are developed for CPUs compatible with x86 2nd generation, first conceived in 1978. Microsoft started moving away from this architecture after Windows 95.)
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Windows_8
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8,486
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In February 2014, Bloomberg reported that Microsoft would be lowering the price of Windows 8 licenses by 70% for devices that retail under US$250; alongside the announcement that an update to the operating system would allow OEMs to produce devices with as little as 1 GB of RAM and 16 GB of storage, critics felt that these changes would help Windows compete against Linux-based devices in the low-end market, particularly those running Chrome OS. Microsoft had similarly cut the price of Windows XP licenses to compete against the early waves of Linux-based netbooks. Reports also indicated that Microsoft was planning to offer cheaper Windows 8 licenses to OEMs in exchange for setting Internet Explorer's default search engine to Bing. Some media outlets falsely reported that the SKU associated with this plan, "Windows 8.1 with Bing", was a variant which would be a free or low-cost version of Windows 8 for consumers using older versions of Windows. On April 2, 2014, Microsoft ultimately announced that it would be removing license fees entirely for devices with screens smaller than 9 inches, and officially confirmed the rumored "Windows 8.1 with Bing" OEM SKU on May 23, 2014.
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Windows_8
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8,487
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Windows 8 was released to a mixed critical reception. Although reaction towards its performance improvements, security enhancements, and improved support for touchscreen devices was positive, the new user interface of the operating system was widely criticized for being potentially confusing and difficult to learn (especially when used with a keyboard and mouse instead of a touchscreen). Despite these shortcomings, 60 million Windows 8 licenses have been sold through January 2013, a number which included both upgrades and sales to OEMs for new PCs.
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Windows_8
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8,488
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Unlike previous versions of Windows, Windows 8 was distributed at retail in "Upgrade" licenses only, which require an existing version of Windows to install. The "full version software" SKU, which was more expensive but could be installed on computers without an eligible OS or none at all, was discontinued. In lieu of full version, a specialized "System Builder" SKU was introduced. The "System Builder" SKU replaced the original equipment manufacturer (OEM) SKU, which was only allowed to be used on PCs meant for resale, but added a "Personal Use License" exemption that officially allowed its purchase and personal use by users on homebuilt computers.
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Windows_8
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8,489
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An upgrade to Windows 8 known as Windows 8.1 was officially announced by Microsoft on May 14, 2013. Following a presentation devoted to the upgrade at Build 2013, a public beta version of the upgrade was released on June 26, 2013. Windows 8.1 was released to OEM hardware partners on August 27, 2013, and released publicly as a free download through Windows Store on October 17, 2013. Volume license customers and subscribers to MSDN Plus and TechNet Plus were initially unable to obtain the RTM version upon its release; a spokesperson said the policy was changed to allow Microsoft to work with OEMs "to ensure a quality experience at general availability." However, after criticism, Microsoft reversed its decision and released the RTM build on MSDN and TechNet on September 9, 2013.
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Windows_8
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8,490
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Windows 8 introduces a new style of application, Windows Store apps. According to Microsoft developer Jensen Harris, these apps are to be optimized for touchscreen environments and are more specialized than current desktop applications. Apps can run either in a full-screen mode, or be snapped to the side of a screen. Apps can provide toast notifications on screen or animate their tiles on the Start screen with dynamic content. Apps can use "contracts"; a collection of hooks to provide common functionality that can integrate with other apps, including search and sharing. Apps can also provide integration with other services; for example, the People app can connect to a variety of different social networks and services (such as Facebook, Skype, and People service), while the Photos app can aggregate photos from services such as Facebook and Flickr.
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Windows_8
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8,491
|
However, according to research firm NPD, sales of devices running Windows in the United States have declined 21 percent compared to the same time period in 2011. As the holiday shopping season wrapped up, Windows 8 sales continued to lag, even as Apple reported brisk sales. The market research firm IDC reported an overall drop in PC sales for the quarter, and said the drop may have been partly due to consumer reluctance to embrace the new features of the OS and poor support from OEM for these features. This capped the first year of declining PC sales to the Asia Pacific region, as consumers bought more mobile devices than Windows PCs.
|
Windows_8
|
8,492
|
Swaziland derives its name from a later king named Mswati II. KaNgwane, named for Ngwane III, is an alternative name for Swaziland the surname of whose royal house remains Nkhosi Dlamini. Nkhosi literally means "king". Mswati II was the greatest of the fighting kings of Swaziland, and he greatly extended the area of the country to twice its current size. The Emakhandzambili clans were initially incorporated into the kingdom with wide autonomy, often including grants of special ritual and political status. The extent of their autonomy however was drastically curtailed by Mswati, who attacked and subdued some of them in the 1850s.
|
Swaziland
|
8,493
|
The constitution for independent Swaziland was promulgated by Britain in November 1963 under the terms of which legislative and executive councils were established. This development was opposed by the Swazi National Council (liqoqo). Despite such opposition, elections took place and the first Legislative Council of Swaziland was constituted on 9 September 1964. Changes to the original constitution proposed by the Legislative Council were accepted by Britain and a new constitution providing for a House of Assembly and Senate was drawn up. Elections under this constitution were held in 1967.
|
Swaziland
|
8,494
|
A small, landlocked kingdom, Swaziland is bordered in the North, West and South by the Republic of South Africa and by Mozambique in the East. Swaziland has a land area of 17,364 km2. Swaziland has four separate geographical regions. These run from North to South and are determined by altitude. Swaziland is located at approximately 26°30'S, 31°30'E. Swaziland has a wide variety of landscapes, from the mountains along the Mozambican border to savannas in the east and rain forest in the northwest. Several rivers flow through the country, such as the Great Usutu River.
|
Swaziland
|
8,495
|
Following the elections of 1973, the constitution of Swaziland was suspended by King Sobhuza II who thereafter ruled the country by decree until his death in 1982. At this point Sobhuza II had ruled Swaziland for 61 years, making him the longest ruling monarch in history. A regency followed his death, with Queen Regent Dzeliwe Shongwe being head of state until 1984 when she was removed by Liqoqo and replaced by Queen Mother Ntfombi Tfwala. Mswati III, the son of Ntfombi, was crowned king on 25 April 1986 as King and Ingwenyama of Swaziland.
|
Swaziland
|
8,496
|
The Swazi economy is very closely linked to the economy of South Africa, from which it receives over 90% of its imports and to which it sends about 70% of its exports. Swaziland's other key trading partners are the United States and the EU, from whom the country has received trade preferences for apparel exports (under the African Growth and Opportunity Act – AGOA – to the US) and for sugar (to the EU). Under these agreements, both apparel and sugar exports did well, with rapid growth and a strong inflow of foreign direct investment. Textile exports grew by over 200% between 2000 and 2005 and sugar exports increasing by more than 50% over the same period.
|
Swaziland
|
8,497
|
The secondary and high school education system in Swaziland is a five-year programme divided into three years junior secondary and two years senior secondary. There is an external public examination (Junior Certificate) at the end of the junior secondary that learners have to pass to progress to the senior secondary level. The Examination Council of Swaziland (ECOS) administers this examination. At the end of the senior secondary level, learners sit for a public examination, the Swaziland General Certificate of Secondary Education (SGCSE) and International General Certificate of Secondary Education (IGCSE) which is accredited by the Cambridge International Examination (CIE). A few schools offer the Advanced Studies (AS) programme in their curriculum.
|
Swaziland
|
8,498
|
Nominations take place at the chiefdoms. On the day of nomination, the name of the nominee is raised by a show of hand and the nominee is given an opportunity to indicate whether he or she accepts the nomination. If he or she accepts it, he or she must be supported by at least ten members of that chiefdom. The nominations are for the position of Member of Parliament, Constituency Headman (Indvuna) and the Constituency Executive Committee (Bucopho). The minimum number of nominees is four and the maximum is ten.
|
Swaziland
|
8,499
|
The considerable spending did not lead to more growth and did not benefit the poor. Much of the increased spending has gone to current expenditures related to wages, transfers, and subsidies. The wage bill today constitutes over 15% of GDP and 55% of total public spending; these are some of the highest levels on the African continent. The recent rapid growth in SACU revenues has, however, reversed the fiscal situation, and a sizeable surplus was recorded since 2006. SACU revenues today account for over 60% of total government revenues. On the positive side, the external debt burden has declined markedly over the last 20 years, and domestic debt is almost negligible; external debt as a percent of GDP was less than 20% in 2006.
|
Swaziland
|
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