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stringlengths 4
164
| label_descriptions
sequence | Another_Study
bool 2
classes | Business_Administrative
bool 2
classes | Covid19
bool 2
classes | Endpoint_Met
bool 2
classes | Ethical_Reason
bool 2
classes | Insufficient_Data
bool 2
classes | Insufficient_Enrollment
bool 2
classes | Interim_Analysis
bool 2
classes | Invalid_Reason
bool 2
classes | Logistics_Resources
bool 2
classes | Negative
bool 2
classes | No_Context
bool 2
classes | Regulatory
bool 2
classes | Safety_Sideeffects
bool 2
classes | Study_Design
bool 2
classes | Study_Staff_Moved
bool 2
classes | Success
bool 2
classes |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Follow up only | [
"Invalid_Reason"
] | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false |
Follow-up end in 1999 | [
"Invalid_Reason"
] | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false |
Following Regulator inspection in 2009, study terminated as inadequate approvals were in place | [
"Regulatory"
] | false | false | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false |
Following a pre-specified interim analysis and Data Monitoring Committee recommendation due to insufficient level of efficacy | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Following a pre-specified interim analysis and Data Monitoring Committee recommendation due toÊ insufficient level of efficacy | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Following an SAE, study was put on hold. After performing preclinical follow-up studies, volunteers were no longer available for continuation." | [
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false | false |
Following recommendation by SOLAR Study IDMC, Astellas closed enrollment in ASP8273 studies. | [
"Business_Administrative",
"Another_Study"
] | true | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Following the recall of Ionsys, the study has been stopped. Data analysis will be undertaken in accordance with the Analysis Plan." | [
"Safety_Sideeffects"
] | false | false | false | false | false | false | false | false | false | false | false | false | false | true | false | false | false |
Following the termination of development and commercialization agreement for S-1 with Taiho Pharmaceutical | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
For Strategic Reasons | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
For business reasons | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
For financial and logistical reasons | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
For safety reasons the recruitment was halted prematurely. Patients on the trial continute to Ê receive treatment and are being followed up as part the protocol. | [
"Safety_Sideeffects"
] | false | false | false | false | false | false | false | false | false | false | false | false | false | true | false | false | false |
Formulation issues. | [
"Logistics_Resources"
] | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
From Sept./08 to April/09 only 30 subjects were recruited. It has proved extremely difficult to recruit subjects. | [
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false | false |
Full Clinical Hold | [
"Business_Administrative",
"Invalid_Reason"
] | false | true | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false |
Funder withdrawn funding. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funders withdrew funding due to slow recruitment | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding Discontinued | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding Period Ended | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding agent withdrew funding | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding allocation to different clinical trials. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding and manpower for this study was unavailable, and completion within a reasonableÊ timeframe was not possible. | [
"Business_Administrative",
"Logistics_Resources",
"Study_Design"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | true | false | false |
Funding and study drugs unavailable | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding associated with enrollment milestones was withdrawn by Sponsor. | [
"Logistics_Resources",
"Business_Administrative",
"Insufficient_Enrollment"
] | false | true | false | false | false | false | true | false | false | true | false | false | false | false | false | false | false |
Funding completed | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding constraints | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding ended | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding ended for the study | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding expired | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding expired, low recruitment | [
"Logistics_Resources",
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | true | false | false | false | false | false | false | false |
Funding expired, low recruitment" | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding for continuation was not received. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding for the CALM-PD Cohort Study was terminated by sponsor. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding has been pulled | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding issue | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding issues | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding issues. | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding limits exceeded prior to complete enrollment. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding nonavailability and principal investigator move | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding not available | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding not available, PI left institution | [
"Business_Administrative",
"Study_Staff_Moved"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | true | false |
Funding not available, study did not open to accrual and will not open in future | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding not available. Could not start this study. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding not obtained | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding not received | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding problem. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding problem; trial abandoned. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding ran out | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding support withdrawn | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding term completed. Final subject accrual for part 3 of study is on hold. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding terminated | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding unavailable | [
"Business_Administrative",
"Logistics_Resources",
"Invalid_Reason"
] | false | true | false | false | false | false | false | false | true | true | false | false | false | false | false | false | false |
Funding unavailable at this time for this particular study. | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding was inadequate to continue; Companies requested closure. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was never granted for this study. No participants were ever enrolled. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was never received so no patients were enrolled. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was not acquired | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was not approved | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was not recieved | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was terminated | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was unable to be secured for this study | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was unavailable to complete the study as originally planned. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding was withdrawn from Drug company | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding will not be provided for the drug | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding withdrawn | [
"Business_Administrative",
"Logistics_Resources"
] | false | true | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Funding withdrawn due to low enrollment | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding withdrawn from study sponsor. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funding withdrawn; study closed due to lack of accrual. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funds for study ended September 30, 2008." | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Funds for this project have been spent, and it is thereby terminated." | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Further development of this compound with ipilimumab in the treatment of melanoma is no longerÊ being pursued. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Further evaluation determined it was not feasible to enroll the post-partum tubal ligation group at our facility | [
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false | false |
Further evaluation of pharmacokinetic data in the target population is ongoing | [
"Interim_Analysis"
] | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false |
Further evaluation of phase I dosing | [
"Another_Study"
] | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Further recruitment into the study was ceased on 10th December 2009, not attributed to safety. All patients recruited in the study completed all study visits." | [
"Invalid_Reason"
] | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false |
Further recruitment terminated after CE mark attained; enclosed patients will be followed up Ê to 5 years | [
"Success"
] | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false | true |
Futility | [
"No_Context",
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | true | false | false | false | false | false |
Futility analysis failed to showed likelihoo of benefit of CoQ 2400 mg/day. | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Futility analysis undertaken, determined that study was underpowered. | [
"Insufficient_Enrollment",
"Study_Design"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | true | false | false |
Futility analysis undertaken, determined that study was underpowered." | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Futility boundary at interim analysis not met | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Futility in enrollment as of May 31, 2011 | [
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false | false |
Futility reasons after Independent Data Monitoring Committee interim analysis | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Future development of AZD1236 is currently under review by the project team and no new studies will be started until this review is completed. | [
"Interim_Analysis"
] | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false |
GSK decision | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
GanLee cancelled study -FDA Draft Guidance: "Clinical Immunogenicity Considerations forÊ Biosimilar & Interchangeable Insulin Products" released 11/25/2019 | [
"Safety_Sideeffects",
"Regulatory"
] | false | false | false | false | false | false | false | false | false | false | false | false | true | true | false | false | false |
GeneSearch_ BLN Assay has been voluntarily withdrawn from the US market. | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Given the number of toxicities seen and the difficulty with patient retention in the doseÊ escalation portion, the sponsor decided to close the trial. | [
"Business_Administrative",
"Safety_Sideeffects"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | true | false | false | false |
Gm test became routinely available. We could not compare the two arms anymore. | [
"Study_Design"
] | false | false | false | false | false | false | false | false | false | false | false | false | false | false | true | false | false |
Grant application was not funded | [
"Logistics_Resources"
] | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
Grant expired | [
"Business_Administrative"
] | false | true | false | false | false | false | false | false | false | false | false | false | false | false | false | false | false |
Greater differences between randomized patients than previously anticipated | [
"Study_Design",
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | true | false | false |
Had been finished | [
"No_Context"
] | false | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false |
Halted by NICHD after recommendation by DSMC to stop for futility | [
"Negative"
] | false | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false |
Halted prematurely due to low enrollment | [
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false | false |
Halted prematurely due to slow accrual | [
"Insufficient_Enrollment"
] | false | false | false | false | false | false | true | false | false | false | false | false | false | false | false | false | false |
HandyLab device determined to not work for the science | [
"Logistics_Resources"
] | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |
HandyLab device did not work for the science | [
"Logistics_Resources"
] | false | false | false | false | false | false | false | false | false | true | false | false | false | false | false | false | false |