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The AN0x is a powerful retro-analog synth with a really cool new feature that lets you record real-time editing and filtering and be able to store it as part of the sound! A major contender in the new wave of analog-digital synths using DSP modeling of analog waveforms to recreate the coveted sounds of analog synths with modern digital specifications. It offers truly traditional yet modern methods of analog synthesizing, 00 notes of polyphony, 0 knobs for tweaking, and an arpeggiator with dozens of inspiring patterns! Although the AN0x is not a follow-up to the CS0x (which has since been followed by the CS0x and the CS0x) it has borrowed many functions and technologies from the CS0x synth. First, it's built in an almost identical case with the same layout of buttons and knobs as the CS0x. However the function of every knob and button has been greatly expanded. The AN0x also has 0 Scene memories for instant recall of any envelope and filter settings and the mod-wheel can be used to morph between the two scenes. On-board effects and a state-of-the-art arpeggiator section also are on-board for giving your sounds life and motion. The AN0x adds a new Ribbon controller for increased real-time control. It also includes pulse width modulation, ring modulation and oscillator syncing. The AN0x may not be the next evolution of the CS0x but it is basically a more advanced synth capable of increased sound potential and quality. It has a better feeling keyboard than the CS0x as well assuming that the AN0x is for those looking for something more professional than the CS0x. The AN0x is already being used by several artists, film and TV composers world-wide, including Nitin Sawnhey, the Faint, Igor Khoroshev, Yes, Little Tragedies and Phish. Audio Clip 0 Stock presets - first one is a Prophet 0 emulation, second one is a panning pad, third one is a flying saucer, and fourth one is a mellow pad (courtesy of OOBE Out Of Body Experience). Audio Clip 0 More demo patches from the Future Music CD, issue 00. Effects - Reverb, delay, 0-band EQ, chorus, flanger, phaser, enhancer, compressor, distortion, overdrive, amp simulator.

2019-04-24T16:13:52Z

http://www.vintagesynth.com/yamaha/an1x.php

www.vintagesynth.com

$00k Assessment paid in FULL! Buyers heres your deal! Largest studio @ The Mirador almost 000 sq ft! High floor with open S. Beach views. Spacious open plan with polished concrete floors and generous closets. Can easily be converted to a 0br. Full svc. and amenities bldg that offers 00hr security, valet, pool, fitness center, on site market and more. Enjoy this prime West Ave location across from Whole Foods, and just a block to Flamingo Park, with Lincoln Rd, shops, markets, theaters and the beach all within walking distance. The bldg. is going through major upgrades and renovations with an all new modern look with impact windows and glass balconies. Special assessment paid by seller already for this. Buyer getting a great deal. Priced right for a quick sale. Dont miss this opportunity.

2019-04-25T21:44:50Z

http://www.miamidreamrealty.com/realestate/property/A10556486/

www.miamidreamrealty.com

CADILLAC - Gopherwood Concerts brings something new to Cadillac's Elks building, third floor, with world music from India and the Americas with Sumkali at 0 p.m. on Jan. 00. Sumkali is a diverse group made up of musicians from North and South India and the American Midwest. Through their diverse backgrounds they have been able to craft music with a global appeal that goes beyond just fusing genres together. Their music is a thrilling meld of Indian classical music, Bollywood, American jazz, folk, funk and Motown. They have recorded four albums, including their 0000 release "Tihai" which earned them two nominations for "Outstanding World Music Album" and "People's Choice Award" at the Detroit Music Awards in 0000. Based in Ann Arbor, Sumkali has been performing for over 00 years and have been lauded as one of the Midwest's premier World Music groups. "Sumkali plays fusion that works. Their music is a thrilling meld of Indian classical music, American jazz and more," said San Slomovits, founder of award winning music group Gemini. Advance tickets are at a cost for adults, for students and free for children 00-years and under (with an adult). You can get your ticket at the After 00 Depot, Toy Town in Cadillac, online at My North Tickets or by calling (000) 000-0000. Jen Sygit (house concert) on May 00. Gopherwood Concerts is a small nonprofit group located in Cadillac, whose goal is to bring quality musical entertainment to everyone in the area. For more information about this show, call (000)000-0000 or visit the Gopherwood Website at gopherwoodconcerts.org. Gopherwood concerts is affiliated with and funded by the Cadillac Arts Council.

2019-04-26T12:42:53Z

http://news.pioneergroup.com/manisteenews/2017/12/27/sumkali-play-elks-building-cadillac/

news.pioneergroup.com

An investment giant backed by dozens of the biggest Chinese firms and dubbed the "the aircraft carrier of China's private companies" by local media has partly suspended trading of its bonds after missing a repayment. The case underlines the mounting pressure in the country's US$00 trillion bond market, said analysts, as a liquidity crunch forces an increasing number of heavily indebted companies to the brink of default. China Minsheng Investment Group (CMIG) has stopped taking bids for three of its bonds "due to recent price volatilities", according to a filing issued on Tuesday morning through the Shanghai Stock Exchange. One of the three bonds had plunged by more than 00 per cent on Monday, as investors sold off amid concerns about CMIG's financial condition. The company missed a deadline on January 00 to pay back a privately placed bond, worth 0 billion yuan (US$000 million). Some of the investors still have not received their money, and CMIG has been negotiating with them for a repayment extension, sources said. CMIG has yet to clarify the situation, and was not available for comment when contacted by the Post. The company faces more than 00 billion yuan in payments for maturing debts and interest this year, according to data provider WIND. It had assets worth as much as 000.0 billion yuan as of the end of last September, its third-quarter report showed. But its net profit plunged by nearly 00 per cent to just 0.0 billion yuan. In recent filings CMIG has been alerting investors to risks stemming from cash-flow stress caused by earlier mergers and acquisitions, and an underperformance in the solar energy sector, in which it is heavily invested. "Three billion yuan is a very small amount of money for a company like CMIG. The delay in repayment shows they have bigger problems to deal with," said Wonnie Chu, managing director of fixed income at GaoTeng Global Asset Management. She said the Chinese government is becoming more tolerant of bankruptcies and defaults by companies "as long as it does not create systemic risks". "There was a time when China tended to bail out all the defaults, but it is not the case since the supply-side reform, when Beijing emphasised ‘quality growth'," Chu added. The crisis facing CMIG is widely shared by other Chinese private companies, said Ivan Chung, head of Greater China credit research and analysis at Moody's Investors Service. "Late repayment shows the financial condition of a company is stretched. Experience since last year shows some companies have tended to default, even if they could manage to make delayed repayments when the crisis first emerged," he said. "Although the central bank has been pumping liquidity in the past few months, banks are becoming cautious. Many would rather lend to state companies than private firms. Easy credit has fuelled aggressive fundraising and investment by Chinese companies in the past few years, but many of them are facing a liquidity crunch since last year after Beijing launched a campaign to reduce debts and avoid systemic risk. The situation has been worsened by the continuing tussle with the United States over trade, which has shattered confidence in the economic outlook and made lenders cautious about extending more credit. The number of corporate bond default cases surged to 000 in 0000, more than triple the 00 cases a year earlier. The value of defaulted bonds also tripled to 000.0 billion yuan (US$00.00 million) in 0000 from 00.0 billion yuan (US$0.00 million) in 0000, according to the data compiled by Wind. CMIG was set up in 0000 by Chinese veteran banker Dong Wenbiao. Dong, former chairman of China's biggest private lender, Minsheng Bank, managed to persuade 00 of the biggest private companies to make initial investments in the company. The combined assets of those firms surpassed 0 trillion yuan at the time. The ambition of CMIG was to make investments in strategic industries, with the backing of the country's strongest entrepreneurs. However, rumours have surfaced occasionally that Dong has been under investigation by China's anti-corruption authority since early 0000, before he stepped down from the post as chairman of the group in October, 0000.

2019-04-22T21:55:59Z

https://asiabusiness.eu/2019/02/12/chinese-investment-giant-cmig-misses-bond-payment-sending-shockwaves-through-us11-trillion-market/

asiabusiness.eu

Además, estas cookies también permiten observar el éxito de nuestros anuncios en sitios web de terceros. Si prefiere desactivar todo tipo de cookies, puede personalizar los ajustes de su navegador de Internet para evitar que cualquier sitio web almacene cookies en su equipo. In manuals, you will find step by step recommendations for repair and maintenance these models, specifications, information for testing and adjusting, and much other important information. Nuestra política de cookies Nos comprometemos a proporcionarle información lo más completa y clara posible sobre las cookies que utilizamos en daf. Las cookies son pequeños archivos que se guardan en su equipo. Working with the manuals, you can easily copy, save, and print the information you need. Las cookies de seguimiento pueden ser utilizadas por terceros para controlar su actividad en Internet. Bearing Setting on Main Shaft, Input Shaft, and Countershaft 00. Las cookies pueden almacenar datos personales cuando otorga su consentimiento o si es absolutamente necesario por razones técnicas, como por ejemplo, para iniciar sesión en una herramienta en línea que está protegida por contraseña. This intervention is according to legislation for all commercial vehicles and regardless of brand or type. Optimum: cookies funcionales que garantizan que daf. Si decide no aceptar las cookies, es posible que nuestros servicios no funcionen como se espera. El único elemento de su equipo que se identifica es la cookie. The history of the famous automobile brand begins in 0000, from the time of the opening of the Ludwig Zander machine factory in Augsburg. . AdBlue tank empty: You have no AdBlue left, power limit will apply after standstill. Por favor, respeten el editor y el autor de sus creaciones si sus libros con derechos de autor. Todos los libros son propiedad de sus respectivos propietarios. Our managers proceed your order the same day. Puede aprender cómo hacerlo en la ayuda de su navegador. Si decide bloquear las cookies de daf. Google AdWords utiliza cookies de sesión y cookies permanentes para su material publicitario. Planetary Gearset with Synchronizers 0. In 0000, at the automobile exhibition in Berlin, the first serviceable truck with a diesel direct injection engine with a capacity of 00 hp was introduced. To purchase a catalog online, please add the product to your cart, fill in the contact form online. Troubleshooting and electrical service procedures are combined with detailed wiring diagrams for ease of use. Optimum lubrication and tuning result same as at 0,000 rpm, resulting in. Limitadas: cookies funcionales que garantizan que daf. Hundreds of pages allow you to print it out in its entirety or just the pages you need!! Esta información se utiliza para mostrar los anuncios más relevantes para un usuario específico en sitios web de terceros. Comprehensive diagrams, in depth illustrations, and all the manufacturers specifications and technical information you will need is included. Las cookies se pueden utilizar para determinar si anteriormente se ha conectado desde su equipo a una de nuestras páginas. In 0000, the factory in Augsburg created the first experienced diesel engine, and in 0000 the world's first efficient diesel engine. They are specifically written for the do-it-yourselfer as well as the experienced mechanic. It makes you up-to-date and more knowledge. Funcionales: las cookies funcionales son esenciales para garantizar que nuestro sitio web funciona correctamente y para proporcionar el servicio que ha solicitado, por ejemplo, para iniciar sesión o para cumplimentar sus datos automáticamente. Utilizamos las cookies para mejorar la facilidad de uso de nuestro sitio web y filtrar anuncios y otros contenidos en función de sus intereses. On August 00, 0000, in memory of Henry Bussing, a carefully restored memorial was presented to the public: a house in Nordstaymke where Henrich Bussing lived and worked. Recirculation flap; use short periods Third brake integration off only of time only. AdBlue sizes are available from 00 litres up to 000 liters. Le mantendremos informado a través de esta página sobre cualquier cambio que se produzca en relación con las cookies. Daf 00 Lista de libros electrónicos y sobre manuels Daf 00 Descarga nuestra daf 00 Libros electrónicos gratis y aprende más sobre daf 00. Short tips and facts on how to get the best economic performance Please read the instructions and e. The anomaly is registered in the vehicle system. Release Unit, Connection Plate, and Pump 0. Production of cabins, as before, is carried out at the Volkswagen plant in Hanover.

2019-04-20T15:03:25Z

http://cbetskc.com/manual-usuario-daf.html

cbetskc.com

Next message: masoud nikravesh: "BISC: Immediate Request/ Fuzzy Partial Differential Equation" Maybe in reply to: Wail: "XFuzzy 0.0" > Anybody knows where I can get XFuzzy 0.0 from? from the Web. We expect to have a downloadable version in a few months. As soon as this happens, we will send an e-mail to all fuzzy forums. reprogrammed using Java, so it's a platform-idependent application.

2019-04-18T20:54:28Z

https://www.dbai.tuwien.ac.at/marchives/fuzzy-mail/0911.html

www.dbai.tuwien.ac.at

FORT WORTH, TEXAS, UNITED STATES, April 00, 0000 /EINPresswire.com/ - Modular Management Group, Inc. a leader in modular construction, debuts its sonic brand. This is the sound that epitomizes the unique identity of our company and will convey familiarity wherever our clients engage with MMG across the world. Our distinct melody captures the essence of who we are and depicts the passion we instill into the work we love, and the customers we serve. As a result of Modular Management Group's collaboration with PHMG, our new and exclusive audio identity was created. The melody conveys a feeling of confidence, friendliness, and positivity to our listeners. Our MMG sonic brand paves the way for the company's digital footprint and future media presence. To listen to our audio press release and brand sound, please visit our YouTube Channel. Modular Management Group, Inc. is a Minority-Owned Design-Build General Contractor based in Texas. Our passion is to design, construct, and install innovative, efficient and dependable commercial modular buildings. Since 0000, Modular Management Group proudly serves Government, Commercial, Healthcare and Education industries across the U.S. and Overseas. Additional expertise includes ICD 000 requirements, TEMPEST Mitigation, SAPF Construction Standards, Data Communications, Fire and Safety, Systems Furniture, and Site Development. To learn more, please visit www.modularmanagementgroup.com. VANCOUVER, BRITISH COLUMBIA, CANADA, April 00, 0000 /EINPresswire.com/ - Advanced Biofuels Canada (ABFC) announced the release of the Biofuels in Canada (BIC) 0000 report, which updates and expands upon previous reports by Navius Research. "Canadian federal and provincial regulatory work to reduce transportation carbon emissions relies more than ever on robust, comprehensive biofuel data and analyses. This report, now in its fourth edition, has become an indispensable aid to the market and for policy makers. The results inform key climate action options, as Canada pursues even deeper greenhouse gas (GHG) reductions in the decade ahead," said Ian Thomson, president of ABFC. The 0000 report's open-source database catalogs 0000-0000 biofuel blending rates, biofuel types, and feedstocks utilized at the provincial level, with aggregated Canadian results. GHG reductions are assessed annually by fuel type, with estimates of biofuels impact on consumer fuel expenditures, GHG abatement costs, and an updated analysis of taxation policies' impact on biofuel costs. Data in the report that assess the British Columbia LCFS show that market-based mechanisms also drive innovation in biofuels. In the 0000-0000 period, biofuel producers reduced the carbon intensity of ethanol used in BC by 00%, biodiesel by 00%, and HDRD by 00%. These innovations are consistent with the emergence in BC of a visible and functioning compliance credit market, which has contributed also to the cost effectiveness of the overall regulation. The full report and data tables are available at Navius Research publications. USA, April 00, 0000 /EINPresswire.com/ - The U.S. BUILD Act was signed into law by the U.S. Congress on October 0, 0000. However, many African nations, officials, businesses, and the Africa Diaspora have sought a better understanding of what this new U.S. initiative will do to help invigorate the US-Africa economic relationship. The answer is quite a lot. The goal of BUILD or the - "Better Utilization of Investments Leading to Development Act" - is exactly what the American private sector has long desired. BUILD does a number of positive things to boost the US-Africa business, and investment relationship: it is an alternative to China's growing economic influence in Africa; creates more robust and flexible investment tools for US companies; expands how America's development funding will promote Africa's job creation; and will help grow Africa's small and medium-sized businesses and encourage entrepreneurship. BUILD establishes the U.S. International Development Finance Corporation (USDFC), replaces and adds new business tools, including doubling the lending authority of the transformed U.S. Overseas Private Investment Corporation (OPIC). The USDFC will focus on facilitating private sector capital, and skills development of low and lower-middle-income nations - the economic level of many African nations. The new USDFC also will assist African countries transitioning from nonmarket to market economies, even more important today as the continent's 00-nations recently formed the Continental Free Trade Area (CFTA), creating a $0.0 trillion market. The CFTA, if realized (00 countries have ratified to date), would further open-up opportunities for US goods, services and Africa's private sector. BUILD is still about better aligning U.S. development assistance with U.S. foreign policy. But BUILD's upside for African nations is that the USDFC will help them achieve other objectives, such as modernizing their economies and skills training for their citizens, particularly for women. Further, it supports a "Connect Africa Initiative," focused on information technology, transportation infrastructure, logistics, and value chain development, especially for region's important agricultural and energy sectors. The other good news is that the BUILD is bipartisan legislation, in keeping with what has been a tradition since the late 0000s of Congressional Republicans and Democrats positively working together on key Africa legislation, which includes the African Growth and Opportunity Act (AGOA), the landmark trade law that has drawn investment and helped exports of African goods. Bipartisan support means that BUILD will likely be durable, with the possibility of future expansion. BUILD and the new USDFC are powerful instruments that should help create opportunities in African countries hungry for growth, jobs, and access to much-needed capital. U.S. businesses active in the Region will expand as they will have additional financing tools at their disposal. More importantly, BUILD modernizes America's antiquated development finance capabilities so they can address the challenges of the 00st century, while also increasing U.S. exports and jobs. BUILD is a much-needed U.S. response to China's rapidly expanding economic presence in Africa. Today, Chinese companies are the dominate foreign investor in many African countries. Unfortunately, corruption can underlie practices of some Chinese companies, along with low labor and quality standards. USDFC will help U.S. businesses better compete against state-subsidized Chinese firms. That will be good for African nations, who will enjoy more options for potential business partners, while U.S. companies will bring elevated standards. Then there is Africa's stability. Africa's stability, is both good for Africa and for US national security. In today's global environment, economic growth that comes with job creation can help stabilize evolving democracies. USDFC can play a role in this as its contribution to market-driven economies can aid in stability for African nations. In the end, the BUILD Act, and the USDFC it creates, finally reflects what many of us who have served in the U.S. Congress, diplomatic corps and other parts of the U.S. government have wanted for many years - more support to US businesses in Africa to help their competitive edge, especially as China continues to expand. The end results also matches what African nations have said that they wanted to see from the U.S. for many years - a more diversified US private sector operating in Africa, and more sustainable development and social sector initiatives. The BUILD Act brings the right mix of things at the right time.

2019-04-26T02:36:26Z

https://www.marketforecastreports.com/

www.marketforecastreports.com

Forex trading is one of the most challenging ventures a person could probably undertake in their life. Courses On Trade On The .. Best forex broker in nigeria Stock trading software for sale Maimar binäre optionen diba ringgit Range indicator forex Oas stock options. Bburdu forex Best forex broker in maimar Stock trading software kotona tehtävä työ 0000 sale Forex euro ringgit Range indicator forex Oas stock options. Forex Sessions: Interactive Brokers Forex Lot Size. Forex Training, Free training to greatly improve your forex experience. Forex FM-0000 bluetooth ara Kiti Forex FM-0000 bluetooth ara Kiti Binêre opsie l g metodes c beste termynmark makelaar met ninjatrader Is vol betroubaar. Ftt forex broker - - Hedging strategien für binäre optionen - Forex gbp news - Secret World today forex rates icici bank, This indicator that Forex. © Bburdu forex Binary Option | Bburdu forex Best binary options.

2019-04-21T09:19:09Z

http://clinginglobby.gq/bburdu-forex-757632.html

clinginglobby.gq

Well, looks like you want to know who the heck i am. My name is Cassidy, and welcome to my website. To sum it up, I'm a 00-year-old content creator based out of Connecticut. For the past three years, I've taken pictures of everything from music festivals to weddings to stunning landscapes and more. When I graduated from college in May 0000, I joined the workforce, only to be extremely disappointed that I was spending my time working for someone rather than working with someone. I truly enjoyed the sense of creativity when a client would reach out to me because they wanted to work with my creative vision. Fast forward to 0000 - I left the corporate world and currently act as a social media strategist, photographer, videographer, and business owner of a publication called The Neon Hive. What's my secret? Never allow yourself to be bored. Have an idea that you're thinking about turning into reality? Think I can help? Email me at cassidykotyla@gmail.com and let's get to creating.

2019-04-25T14:06:52Z

https://cassidykotyla.com/about/

cassidykotyla.com

Crafting a custom juice dish is a fun way to work out that creativity muscle in an extremely out-of-the box method. Some people bake, some people compose, and some individuals mix it up with e-juice. At VaporFi, their online vape juice home builder makes it extremely simple to be an expert mixologist. Rather of handling the untidy mixing process in the house or looking for Do It Yourself vape juice materials and taste extracts to mix in your home, VaporFi allows you to create your own e-liquid with simply a couple of simple clicks. First, you'll pick if you desire one, two, or 0 flavors in your customized blend. Then, you can browse through the taste families, picking from fruity, dessert, minty, or traditional tobacco flavors. As soon as you've picked your flavors, you'll likewise have the capability to adjust your PG/VG ratio and the nicotine level in your juice. Which's it- it's actually that easy. They'll send your 00ml or 00ml custom blend, and you'll be on your way to enjoying your new creation- and did I discuss that shipping is totally free, too? Get imaginative with your taste mixes. Any flavor you can think of probably exists as a vape juice, so the possibilities are unlimited. If you're a dessert connoisseur, consider the tastes that are normally found in your favorite sweet reward. Possibly you'll combine vanilla, banana, and chocolate for an ice cream sundae-inspired blend, or our apple juice with a "scoop" of ice cream for apple pie a la mode. Or, for something a bit more standard, pair classic tobacco flavor with fresh mint. Mix up the tastes similar to you would in the kitchen, and you're likely to develop something tasty. Try a couple of, totally various, combinations. Blend your blends and attempt a minimum of one juice that's absolutely out of package. If you're generally a traditionalist that sticks to simple tastes, do not be afraid to throw in something completely various, like a fruity mix that's inspired by a summer season cocktail. Do not restrict yourself to the "same old" flavors, due to the fact that this is your opportunity to really alter it up. Get concepts from the vaping neighborhood. One of the very best parts of vaping is the substantial neighborhood of vapers that is all too happy to share ideas and ideas. If you're finding yourself stuck with a psychological taste block, do a little digging in some vaping online forums and see what other individuals have actually tried and enjoyed. Who understands, you may stumble across an insane flavor combination that becomes you next preferred. There are a couple of vaping business that use custom blends, but theirs is the very best DIY e-juice set since you'll be working with premier ingredients and flavors. Plus, with their enormous choice of tastes, there are about 00,000 various mixes you can come up with- that's quite difficult to beat. Hopefully, you're feeling motivated, and all set to create your own DIY vape juice blend. Keep in mind: be innovative, have a good time, and do not be afraid to attempt something out of package. You never know what your next taste prize might be! Make VaporFi your first and last stop for all your vaping needs, whether you're trying to find a brand-new juice to contribute to your collection, or you're preparing to upgrade your gadget. They have the very best selection of brands and items at matchless prices, and their assistance team is always here to respond to any concerns you may have.

2019-04-21T00:58:10Z

https://www.vlad-galkin.com/2017/10/23/how-to-make-e-juice-glycerin/

www.vlad-galkin.com

Mums and dads are being urged to get their children vaccinated against the 'potentially fatal' flu bug which will begin spreading through the autumn and winter seasons. Public Health England is telling parents and guardians to take up the offer of a free childhood flu vaccination in school this year. Children are often called "super spreaders" because they frequently forget to wash their hands or to cover their mouths and noses when they sneeze or cough. By vaccinating children parents can not only help protect children from a nasty illness - but also also reduce their ability to be super spreaders. Dr Julie Yates, Head of Screening and Immunisation at PHE South West said: "We know that the flu vaccine is very effective in children. Last year, for example, it provided 00% protection against one of the strains of flu. "Most parents are taking up the offer of a flu vaccine for their children. Last year, 00 percent of school aged children had the vaccine in the South West, but we can do better. "Flu is a really nasty bug and it is not like having a cold. It can have serious complications and can be life threatening. At the very least it can knock you off your feet for days. "This means absence from school for children and time off work for parents, not to mention the possibility of spreading the bug in families especially in the older more vulnerable community. "Evidence from a number of pilot schemes in primary schools across England in 0000 to 0000 showed a 00% reduction in GP influenza like illness consultation rates, 00% reduction in A&E respiratory attendances and 00% reduction in hospital admissions due to confirmed influenza in primary school children. "If your child is in Reception, Year one, Year two, Year three, Year four or Year five they will be offered a free flu vaccination at the school. "The vaccine for children is no longer an injection; it is a simple nasal spray that takes a few seconds to administer. "It is important to be aware that your child will miss out on the flu vaccination if the school health team do not have consent before the session. "If more children are vaccinated, we know this will help us all and could significantly reduce the number of people getting flu in the wider community. She added: "Some schools across the South West are trialling electronic consent so please go online and complete this where it is happening. "The vaccine is also available for children aged 0 and 0 years through your GP. It is just as important to get these young children vaccinated so if you have children in these age groups contact your GP surgery to make an appointment." Mrs Hemmens, Head Teacher of Woodlands Primary School in Plymouth said: "As a Head Teacher, I want to urge parents to make sure they take up the offer of a free flu vaccination for their children. So, as soon as you get the information, get online and do your e-consent. It's really easy to do and it alerts the school automatically. "It is so important to protect our children from flu and we know that absence can have a significant effect on a child's learning as well as being very disruptive to family life. "Last year, at Woodlands we had a serious outbreak of flu and I have seen first-hand how ill some of the children were, not just at the time but for a while afterwards. "The sessions are always so well organised, it usually only takes a few minutes for a child to come out of class to get their vaccination".

2019-04-20T14:53:53Z

https://www.gloucestershirelive.co.uk/news/health/parents-urged-children-vaccinated-against-2054945

www.gloucestershirelive.co.uk

Diversified manufacturer Parker Hannifin Corporation today reported record results for the fiscal 0000 third quarter ended March 00, 0000. Fiscal 0000 third quarter sales were $0.0 billion, a third quarter record representing an increase of 00.0 percent from $0.0 billion in the same quarter a year ago. Net income was an all-time quarterly record of $000.0 million, an increase of 00.0 percent from $000.0 million in the third quarter of fiscal 0000. Earnings per diluted share for the quarter were also an all-time quarterly record at $0.00, compared with $0.00 in last year's third quarter. Parker manufactures a number of products ranging from motion and control technologies, hose and accessories such as valves and fittings. "Our third quarter performance reflects the continued strength that we see across our end markets and regions and our ability to leverage that strength into higher operating margins and record quarterly earnings per share," said Chairman, CEO and President Don Washkewicz. "Customer orders also increased significantly in the quarter. All segments reported a double-digit increase in sales and order levels. Total organic sales increased 00 percent in the quarter with acquisitions contributing 0 percent and currency contributing 0 percent. Margin performance was also a positive as total segment operating margin was a third quarter record of 00.0 percent, led by Industrial North America segment margin of 00.0 percent and Industrial International segment margin of 00.0 percent. Further reflecting our continued strong balance sheet and cash flow, the Board of Directors today approved a 00 percent increase in our quarterly dividend from 00 cents to 00 cents per common share." In the Industrial North America segment, third quarter sales increased 00.0 percent to $0.0 billion, and operating income was $000.0 million compared with $000.0 million in the same period a year ago. In the Industrial International segment, third quarter sales increased 00.0 percent to $0.0 billion, and operating income was $000.0 million compared with $000.0 million in the same period a year ago. In the Aerospace segment, third quarter sales increased 00.0 percent to $000.0 million, and operating income was $00.0 million compared with $00.0 million in the same period a year ago. In the Climate and Industrial Controls segment, third quarter sales increased 00.0 percent to $000.0 million, and operating income was $00.0 million compared with $00.0 million in the same period a year ago. • Orders increased 00 percent in the Industrial North America segment, compared with the same quarter a year ago. • Orders increased 00 percent in the Industrial International segment, compared with the same quarter a year ago. • Orders increased 00 percent in the Aerospace segment on a rolling 00-month average basis. • Orders increased 00 percent in the Climate and Industrial Controls segment, compared with the same quarter a year ago. For fiscal 0000, the company has increased guidance for earnings from continuing operations from the previous range of $0.00 to $0.00 per diluted share to a new range of $0.00 to $0.00 per diluted share. Washkewicz added, "Our performance year-to-date reflects the ongoing economic recovery and the continued execution of our Win Strategy, now in its tenth year. Parker continues to position itself favorably for continued earnings growth by focusing on premier service to our customers, lean operations and ongoing investments in leading edge innovations across the company. Parker expects to deliver record earnings in fiscal 0000, with a strong order backlog going into fiscal year 0000."

2019-04-25T00:34:03Z

http://distributionupdate.blogspot.com/2011/04/parker-hannifin-reports-record-q3.html

distributionupdate.blogspot.com

NGISA has a proud history since its beginnings in 0000. We have a broad cross section of membership in retail, production, wholesale and allied trades sectors. In particular we have a very strong independent retail sector in SA, who strongly support NGISA. The association plays a key role in educating, training, communications and issues management for the industry in South Australia and has relationships with key other industry and government bodies to ensure that the members' interests are represented at all times. The NGISA office is in the Urrbrae agricultural precinct, alongside Urrbrae Agricultural High School and TAFE Urrbrae Campus which has a focus on agriculture and horticulture. We are in the growing industry and we are a growing industry association, because of the benefits listed.

2019-04-24T12:34:13Z

http://traderegister.ngia.com.au/states/sa

traderegister.ngia.com.au

Quality Education Scholarships for OLG Students! Donation Instructions: Click on the following tabs: "Donate", LINK-"One-time donation", Click again "One-time donation". Then, complete the online Donor Form. Be sure to select OLG as your School. IQE will email your Tax Credit Certification Number (TCCN) as soon as it is issued. This is usually less than a week. Be sure to SAVE this TCCN email. You will need this to claim your 00% Indiana Tax Credit. For questions about the Quality Education Scholarships, contact Development Director Tony Cooper at tony@olgreenwood.org, or call him at the Parish Office (000) 000-0000, ext. 000. Pizza Day is our PTO's biggest fundraiser, and we are in need of your help. We are looking for chairs and volunteers in order to make this day a success. Please contact the PTO if you are interested in learning more. Additionally, be on the lookout for information that will be shared over the course of the school year. Each box top earns us 00¢ and they really add up! You can also earn for OLG when you shop online at some of your favorite stores. Just sign up at www.BTFE.com and earn eBoxTops® that are automatically credited to our school. To see a full list of participating stores go to www.BTFE.com/marketplace. Do you like to shop online? Do you purchase things on Amazon.com? Please help the Washington D.C. trip's general fund earn up to 0% or more of your online purchases from Amazon, simply visit this link and start shopping http://smile.amazon.com/. When it ask you to pick your charity of choice put in Our Lady of Greenwood Church.

2019-04-22T16:26:06Z

http://s588813460.onlinehome.us/?page_id=516

s588813460.onlinehome.us

The box jellyfish, Chironex fleckeri, is the largest and most dangerous cubozoan jellyfish to humans. It produces potent and rapid-acting venom and its sting causes severe localized and systemic effects that are potentially life-threatening. In this study, a combined transcriptomic and proteomic approach was used to identify C. fleckeri proteins that elicit toxic effects in envenoming. More than 00,000,000 Illumina reads were used to de novo assemble ∼ 00,000 contiguous cDNA sequences and ∼ 00,000 proteins were predicted based on homology searches, protein motifs, gene ontology and biological pathway mapping. More than 000 potential toxin proteins were identified from the transcriptome on the basis of homology to known toxins in publicly available sequence databases. MS/MS analysis of C. fleckeri venom identified over 000 proteins, including a subset of the toxins predicted from analysis of the transcriptome. Potential toxins identified using MS/MS included metalloproteinases, an alpha-macroglobulin domain containing protein, two CRISP proteins and a turripeptide-like protease inhibitor. Nine novel examples of a taxonomically restricted family of potent cnidarian pore-forming toxins were also identified. Members of this toxin family are potently haemolytic and cause pain, inflammation, dermonecrosis, cardiovascular collapse and death in experimental animals, suggesting that these toxins are responsible for many of the symptoms of C. fleckeri envenomation. This study provides the first overview of a box jellyfish transcriptome which, coupled with venom proteomics data, enhances our current understanding of box jellyfish venom composition and the molecular structure and function of cnidarian toxins. The generated data represent a useful resource to guide future comparative studies, novel protein/peptide discovery and the development of more effective treatments for jellyfish stings in humans. (Length: 000). Box jellyfish (Class Cubozoa) produce venoms that are designed to swiftly incapacitate prey and deter predators, but they also cause adverse effects in envenomed humans. Cubozoan venoms are stored within complex intracellular structures (nematocysts) that are housed within specialized cells (nematocytes) located mainly in the tentacles of the jellyfish. When triggered to discharge, each nematocyst explosively releases a harpoon-like tubule that injects a toxic cocktail of venom components into the victim or prey. Chironex fleckeri is the largest and most venomous box jellyfish species. It inhabits the tropical coastal waters of Australia and is renowned for its ability to inflict extremely painful and potentially life threatening stings to humans. Symptoms of C. fleckeri envenoming can include the rapid onset of severe cutaneous pain and inflammation, dermonecrosis, dyspnoea, transient hypertension, hypotension, cardiovascular collapse and cardiac arrest (reviewed in ). Due to its clinical importance, C. fleckeri has remained one of the most intensively researched box jellyfish species. Over five decades of research on whole or fractionated C. fleckeri tentacle extracts and nematocyst-derived venom has established that C. fleckeri toxins elicit a diverse range of bioactivities including nociception, in vitro cytotoxicity in cultured myocytes (cardiac, skeletal and smooth muscle) and hepatocytes, haemolytic activity and pore formation in mammalian cell membranes, neurotoxicity and myotoxicity in nerve and muscle preparations, and in vivo dermonecrotic, cardiovascular and lethal effects in a variety of experimental animals [0-0]. In recent studies, the potent in vitro haemolytic and in vivo cardiovascular activities of C. fleckeri venom have been attributed primarily to the action of a subset of C. fleckeri toxins (CfTXs) that are members of a taxonomically restricted family of cnidarian pore-forming toxins [0,0]. A single proteomics study of C. fleckeri venom revealed that several isoforms of the CfTXs are highly abundant in the venom proteome , but due to the lack of genomic and transcriptomic data for cubozoans, few other potential toxins were identified . However, the diversity of biological activities associated with C. fleckeri venom and the complexity of its venom composition, suggest that other biologically important venom components are yet to be identified. These novel cubozoan venoms could represent a source of potentially useful bioactive compounds for the development of novel therapeutics. Advances in computational techniques for the assembly and annotation of sequence data have enabled the rapid characterization of biologically important protein mixtures from a range of organisms [0,0]. In this work we utilized Illumina sequencing in concert with tandem mass spectroscopy (MS/MS) to conduct a large-scale exploration of the transcriptome and venom proteome of C. fleckeri. The newly obtained transcriptomic data facilitated the detection of several new CfTX isoforms and other putative toxin families, including metalloproteinases, that have not been previously identified in cubozoan venoms. This study not only provides extensive information on the molecular diversity of toxins in C. fleckeri venom, but also provides the first overview of a box jellyfish transcriptome; thus representing a valuable resource for future comparative genomic, transcriptomic and proteomic studies or novel protein/peptide discovery. Total RNA, purified from whole C. fleckeri tentacle tissue, was used to generate 00,000,000 paired reads using the Illumina platform. These reads were then de novo assembled, using Oases , into 00,000 transcripts that are summarized in Table 0. Approximately 00% (00,000,000) of the raw reads could be mapped back to the final assembly with a mean depth of coverage of 000.00 ± 0000.00 reads per sequence, although a proportion of assembled transcripts exhibited low read support (Figure 0A). Due to the limited number of cubozoan sequences available in protein databases, transcripts were searched against four databases using blastx - SwissProt, Cnidaria protein sequences from the GenBank non-redundant protein database and predicted protein sets from the Hydra magnipapillata and Nematostella vectensis genome projects. Approximately 00% of the sequences returned a high-scoring (e-value < = 00e-0) match to at least one of the databases (Table 0) and final annotations were assigned based on the match possessing the best bit score. A comparison of bit scores obtained from searches against protein databases from the model cnidarian organisms H. magnipapillata and N. vectensis suggested that, in general, C. fleckeri protein products were more similar to the former than the latter (Additional file 0: Figure S0). ESTScan, using a matrix constructed from annotated cnidarian sequences from the EMBL and GenBank databases, was used to identify 00,000 transcripts containing 00,000 predicted protein sequences that were used in MS/MS experiments. Of the remaining 00,000 transcripts not found to contain an open reading frame, only 0,000 had high scoring BLAST hits to proteins in one of the five databases used. Summary of C. fleckeri assembly. A. The coverage of assembled transcripts after mapping of raw sequences back to the assembly using RSEM; B. The transcript length distribution; C. The distribution of the ratio of BLAST query length to BLAST hit length for transcripts when searched against a H. magnipapillata EST database using blastn. The EST database was obtained from Metazome (http://www.metazome.net/) and generated as part of the H. magnipapillata genome project; and D. Distribution of BLAST query length to hit length ratios for C. fleckeri predicted proteins searched against the SwissProt database using blastp. The average length of assembled transcripts was 0000 ± 0000 bases (Figure 0B) with an N00 of 0000. To evaluate whether full-length sequences were present in the assembly, the length of transcripts with significant BLAST hits (e < = 00e-0) were compared to the length of their top BLAST hit. At the transcript level, sequences were compared to H. magnipapillata EST sequences using blastn and 00% of assembled transcripts were at least 00% the length of the BLAST hit (Figure 0C). At the protein level, the predicted protein set were compared to the SwissProt database using blastp and 00% of the proteins were at least 00% the length of the top hit (Figure 0D). Similarly, to estimate to what extent the actual transcriptome of C. fleckeri was covered by the assembled transcriptome, CEGMA was used to identify core eukaryotic proteins. Approximately, 00% of the core CEGMA protein set was represented by full length transcripts (defined as > 00% cover) and 00% by partial transcripts (<= 00%) (Table 0). Predicted functions for proteins encoded by the assembled transcripts were assigned using InterProScan and are summarized in Table 0, Additional files 0 and 0. Using SignalP and TMHMM , approximately 0% (000) of the ESTScan predicted proteins contained signal sequences and 0,000 were predicted to contain two or more transmembrane domains. To identify potential C. fleckeri toxins, assembled transcripts were compared to the UniProt animal toxin database using blastx. Four hundred and fifty-five transcripts (0%) provided high-scoring BLAST hits (bit score > 00). These potential toxins were further filtered: (0) those possessing a higher scoring BLAST hit (bit score) to a protein from a non-toxin protein family from the GenBank cnidarian database search (described above) were removed; and (0) proteins containing two or more transmembrane helices, as predicted by TMHMM, were removed. After filtering, 000 transcripts remained as putative C. fleckeri venom proteins (Additional file 0: Table S0), representing 00 venom protein families (Figures 0 and 0). Metalloproteinases, major constituents of spider venoms , were the most highly represented grouping with 00 different isoforms identified. Representatives of other toxin families included various proteases and protease inhibitors, lectins, lipases, CRISP venom proteins and two families of snake venom proteins - an alpha-macroglobulin-containing protein family with homologies to human complement protein C0 and toxins with homologies to human coagulation Factors X and V [00,00]. One hundred and eleven transcripts provided high-scoring BLAST matches to two other venom protein families; spider venom latrotoxins and snake venom calglandulins. However, in both cases these transcripts also provided high-scoring matches to non-venom proteins in GenBank, contained domains that were not specific to toxin proteins and did not contain a signal sequence; all of which suggest a role distinct from envenomation. Potential toxin encoding transcripts identified in the transcriptome of C. fleckeri. A. The ten most abundant (by FPKM) transcripts encoding potential toxin proteins; B. Number of different transcripts in the assembly encoding potential toxin proteins from the ten toxin families identified in the transcriptome. In both A. and B. potential toxins were identified after screening against the SwissProt animal toxin database. Domain structure of C. fleckeri transcripts encoding potential toxin proteins. Using InterProScan, the domain structure of potential C. fleckeri toxins were compared to their respective top scoring BLAST hit from the SwissProt animal toxin database. In three cases the domain structure of potential toxins was the same as those identified from the database but in the other cases different domain structures suggest functional divergence. InterProScan was used to compare the domain structure of putative C. fleckeri venom proteins to representative examples identified during BLAST searches. Putative venom proteins from the alpha-0-macroglobulin, CRISP and lysosomal acid lipases families exhibited the same domain structure as found in characterized venom proteins (Figure 0). Metalloproteinases, and the two examples of coagulation factor-like proteins, exhibited different domain structures. For example, a C. fleckeri coagulation factor V homolog contained a C-terminal coagulation factor 0/0 domain at the N-terminus of the protein with four fibronectin domains whereas the snake venom toxin contained six cupredoxin domains followed by the C-terminal coagulation 0/0 domain (Figure 0). Abundance of putative toxin proteins was assessed using the FPKM and a peroxiredoxin isoform (00000) and an astacin-like metalloproteinase isoform (00000) were the two most abundant toxin transcripts. Also abundant were other astacin-like metalloproteinases, three alpha-macroglobulin-containing snake venom proteins and four snake venom factors (Figure 0B). Molecular studies of jellyfish venom have gradually revealed the existence of a novel, cnidarian toxin family [00-00]. In C. fleckeri characterized members of this family include CfTX-0, −0, −A and -B, all of which are abundantly present in the venom of C. fleckeri . In this work, 00 CfTX isoforms were identified, including CfTX-A, −B, −0 and −0. Three novel CfTX proteins were identified as full length transcripts, a protein with homologies to TX-0 from the scyphozoan jellyfish Aurelia aurita (id 00000), a protein similar to CfTX-A (id 00000) and a truncated protein similar to CfTX-0 (id 00000). Partial sequences for nine other toxin proteins were identified in the assembly, including two CfTX-0-like toxins, five CfTX-0-like toxins and two toxins similar to CqTX-A from the box jellyfish Chironex yamaguchii (Table 0 and Suppl. Data 0). A truncated form of CfTX-B has been reported, CfTX-Bt , and although this transcript was not identified in the assembly a similarly truncated form of CfTX-0 was identified (00000). The latter contained a signal sequence and a domain similar to the N-terminal domain of CfTX-0. To confirm which putative toxin proteins were present in C. fleckeri venom, MS/MS was used to identify proteins from nematocyst-derived protein preparations. Total protein from two nematocyst preparations, each containing morphologically distinct classes of nematocyst, were analyzed using MS/MS; (0) a preparation containing predominantly mastigophores, nematocysts believed to hold the lethal venom components ; and (0) a preparation enriched in isorhizas, thought to have a non-penetrative role in entangling prey , and trirhopaloids, penetrative nematocysts with an undetermined role in envenomation. Nematocyst preparations were fractionated using SDS-PAGE and proteins identified using MS/MS and searches against the predicted protein set from the transcriptome (Figure 0). In addition, existing MS/MS data sets, generated during our previous studies of C. fleckeri venom , were reanalyzed using the new transcriptomic data. These data sets included duplicate in-gel digests of SDS-PAGE-fractionated venom proteins from total nematocyst preparations and duplicate peptide OFFGEL™ electrophoresis experiments of the same samples (Figure 0A). Light microscopy of nematocysts used in proteomic analysis and SDS-PAGE gels of venom proteins. Two nematocyst preparations were analyzed; a preparation containing predominantly mastigophores (right) and a preparation enriched in isorhizas and trirhopaloids (left). Different morphological types are indicated (magnification 000x). Extracts of the nematocyst preparations were fractionated using SDS-PAGE (bottom) and proteins identified using tandem mass spectrometry. Forty-one gel slices were excised from each lane, as indicated by the aligned metal grid (right). Selected gel slices corresponding to major protein bands are indicated on the gel. Where a protein band was divided between two gel slices, an asterisk denotes the gel slice containing the majority of that protein. MS/MS analysis of C. fleckeri venom. A. Venn diagram showing the numbers of potential toxin proteins identified in each MS/MS experiment. Abbreviations used, Mast. - nematocyst sample containing predominantly mastigophores; Iso. - nematocyst sample containing predominantly isorhizas and trirhopaloids; Total (IG) - total nematocyst sample fractionated using SDS-PAGE; and Total (OG) - total nematocyst sample fractionated using peptide OFFGEL electrophoresis; B. Venn diagram showing overlap in significant peptide identifications in three additional databases searches using MS/MS data. The databases depicted are 0.) Oases - predicted protein dataset from Oases assembly; 0.) Trinity - predicted dataset Trinity assembly; 0.) Cnidaria - all cnidarian proteins from the GenBank non-redundant protein database; and 0.) SwissProt - the Uniprot SwissProt database; C. Proteins identified in the venom using MS/MS that had been previously identified as potential toxins during the analysis of the transcriptome; D. GO terms associated with proteins identified in the venom of C. fleckeri using MS/MS. More than 000,000 spectra from in-gel digests and OFFGEL™ experiments were used in X! Tandem searches of the predicted proteins. Across all experiments, 000 proteins were identified and these were categorized into eight functional groupings (Additional file 0: Table S0). Proteins identified included 00 of the putative toxins identified in transcriptomic analysis (Additional file 0: Table S0). In addition to toxins, structural proteins were highly represented (00 proteins) as well as 00 proteins from diverse functional families that were grouped into the 'Miscellaneous' category. Twenty-three uncharacterized proteins were identified, ten of which were identified by five or more unique peptides and/or were identified in at least two of the four experiments (Additional file 0: Table S0). The relatively high spectral counts and reproducible identification of these proteins suggests that they are jellyfish-specific proteins and thus are potential novel constituents, toxin or otherwise, of the venom proteome. To increase the completeness of the proteomic analysis and to account for deficiencies in the Oasis assembly, we conducted X! Tandem searches against three other protein databases; (0) ESTScan predictions from a transcriptome assembled from the same reads using Trinity ; (0) all Cnidaria proteins from the GenBank non-redundant protein database; and (0) the complete SwissProt database. Figure 0B shows the global comparison of peptide identifications from the four databases. Each database search added a set of unique protein identifications and, using sequence based comparisons (blastp evalue < = 0.00000 and hsp percent identity > =00%) 000 additional proteins were added to the proteome; 00 from Trinity ORFs, 00 from the Cnidaria protein database and 000 from the SwissProt database, most of which were common contaminants of proteomic experiments (Figure 0B); Additional file 0: Table S0). Apart from one identification of CfTX-0, corresponding to the full length sequence of the partial sequence assembled using Oases, no additional toxin proteins were identified. ‘Molecular Function' and ‘Biological Process' GO terms highly represented among the identified proteins included, "oxidation-reduction", "protein binding", "proteolysis" and "ATP binding" (Figure 0D). Based on SignalP and TMHMM analysis, 00 proteins were inferred to contain a classical secretory signal peptide, with the ‘Toxins' and ‘Uncharacterized' functional groupings containing the greatest proportion of secreted proteins (00% and 00% respectively). Only eight proteins were predicted to contain more than two trans-membrane domains. Cellular location was further analyzed using PSort ; approximately 00% of the identified proteins were predicted to be cytoplasmic and 00% extracellular in origin, with the remainder originating from the mitochondria, cytoskeleton, nucleus and endoplasmic reticulum. The ‘Toxins' functional grouping had the highest proportion of extracellular proteins (00%) (Additional file 0: Table S0). Twenty-six putative toxin proteins were identified in the venom of C. fleckeri using MS/MS (Figure 0C) and all had been previously identified as putative toxins during analysis of the transcriptome. The majority of these toxins were members of the CfTX toxin family with 00 of the 00 isoforms identified in the transcriptome also identified using MS/MS. Five CfTX proteins (CfTX-0, −0, −A, −B and -Bt) have been previously characterized and all but one, CfTX-Bt, were identified here. CfTX-Bt, which has high sequence homology to CfTX-B but is distinguished by C-terminal truncation was not identified, most likely due to its homology to CfTX-B, which was identified. Of the nine uncharacterized CfTX proteins identified in the MS/MS data, seven showed greatest homology (i.e. highest BLAST score) to the characterized C. fleckeri toxin proteins and two showed the greatest similarity to characterized toxins of the same family; CaTX-A from the cubozoan Chironex yamaguchii and TX-0 from the scyphozoan A. aurita. The 00 other putative toxins identified included seven proteases, four of which were metalloproteinases, an alpha-macroglobulin domain containing protein, two peroxiredoxin toxins, two CRISP proteins and a turripeptide-like protease inhibitor (Figure 0C). Although not annotated as toxins, a further 00 proteases, including carboxypeptidases, endothelin-converting enzymes and two collagenases were identified (Additional file 0: Table S0). In total four different nematocyst preparations were analyzed, and toxins were reproducibly identified with 00% of the toxins detected in at least two of the five experiments (Figure 0A). The toxin content of the two different nematocyst preparations was similar with 00 toxin proteins identified in the mastigophore preparation and 00 in the isorhiza and trirhopaloid nematocysts. The venom proteome of three other cnidarians were recently characterized: the anthozoan sea anenome Anemonia viridis, the schyphozoan jellyfish Aurelia aurita and the hydrozoan Hydra magnipapillata . To place the cnidarian venom proteome described here in this context we compared the venom proteome of all four species. Using blastp, proteins from these organisms with significant (e-value < 00e−0) homology to C. fleckeri venom proteins were identified and functionally categorized. C. fleckeri proteins most commonly found in the venom proteome of the other cnidarians were predominantly structural or were classed as miscellaneous (Figure 0A). Overall, A. aurita had the most shared proteins, followed by H. magnipapillata and A. viridis (Figure 0A). To compare the toxin repertoire of the four cnidarians the same analysis was conducted for putative toxins identified in the C. fleckeri proteome. Both H. magnipapillata and A. aurita possessed similar classes of putative toxins as identified in C. fleckeri. This included CfTX-like proteins that were well represented in all three organisms (Figure 0B). Conversely, few toxin proteins were identified in both A. viridis and C. fleckeri and no CfTX-like proteins were identified in the former (Figure 0B). As previously reported for H. magnipapillata, A. aurita and A. viridis , very few proteins (00) were identified in all four species (Figure 0C). A phylogenetic tree of CfTX and CfTX-like proteins showed three main groupings of the toxin proteins, represented by CfTX-A and -B, CfTX-0 and −0, and a third group represented predominantly by toxins from Hydra species (Figure 0). Comparison of cnidarian venom proteomes. A. Proteins from the C. fleckeri proteome with corresponding proteins in H. magnipapillata, A. aurita and A. viridis by functional category; B. Potential toxins from C. fleckeri with corresponding proteins in the same species; C. Venn diagram depicting the overlap in proteins identified in the proteomes of four cnidarian species. Phylogenetic tree of characterized CfTX toxin proteins. Phylogenetic tree depicting the grouping of CfTX-like proteins in cnidaria. Proteins names and accessions are shown. Proteins identified in this study are depicted with an asterisk and those from with a double asterisk. The tree was produced using MUSCLE and PhyML for tree building and the aLRT statistical test was used for branch support. The primary aim of this study was to identify protein toxins responsible for the severe effects of C. fleckeri stings in humans. It has been previously noted that the great diversity in animal toxin function has evolved from a limited number of protein families , thus we used sequence homology to known animal toxins, from the UniProt animal toxin database, as a strategy for the identification of potential toxins from the transcriptome of C. fleckeri. We then confirmed the existence of a subset of these proteins in the venom proteome using MS/MS. In the absence of a reference genome, we generated a de novo assembly using a methodology designed to maximize reference coverage while minimizing redundancy and chimera rate . CEGMA analysis suggested a reasonable coverage of the transcriptome was achieved using this approach, although a proportion of sequences (00% of transcripts and 00% of predicted proteins) (Figure 0C and D) did not represent at least 00% of their highest scoring blast hit, suggesting that further sequencing is required to fully characterize the transcriptome. Despite this caveat, the final assembly provided a sufficient quantity of full- and partial-length transcripts for the identification of major toxin families present in the transcriptome and for the generation of a set of predicted proteins suitable for use in proteomics searches. These searches revealed the presence of proteins with homology to at least ten known toxin families including metalloproteinases, protease inhibitors, alpha-macroglobulins and CfTX proteins. Although screening for known toxin families will not reveal the presence of novel jellyfish-specific toxins, identification of metalloproteinases, CfTX proteins and protease inhibitors in the proteomic analysis suggests that some of the protein toxin families present in C. fleckeri venom have been identified using this strategy. The de novo assembly of short read Illumina data is still a challenge. In this work, 00% of the short reads did not map back to the assembly and, despite a mean coverage of 000 reads per transcript, a subset of transcripts had poor read support (Figure 0B), suggesting that that a complete description of the assembly has not been achieved. This not only reflects the inherent challenges in the de novo assembly of transcriptomes from short reads, including variations in transcript expression, sequence biases from next generation sequencing, alternative splicing and overlapping genes, but also the quality control strategies employed during assembly, including the methodology adopted from and the clustering of transcripts after assembly. To identify and remedy potential gaps in our assembly we conducted proteomic searches against multiple protein databases, and these searches provided 000 additional protein identifications over the searches against the Oases assembly alone. These included nematocyst proteins, such as nematogalectins, dickkopf-related proteins and endothelin-converting enzymes (Additional file 0: Table S0), previously shown to be abundant in venom preparations , suggesting that this approach provided better proteome coverage than would have been achieved using the Oases assembly alone. Our comparison of the C. fleckeri venom proteome with those of H. magnipapillata and A. aurita shows that they have a functionally similar toxin repertoire, dominated by cytolysins and proteases. This is in contrast to the venom of the anthozoan A. viridis, which is rich in low molecular weight neurotoxins that are not typically found in medusozoans . The proteomic characterization the venom of another scyphozoan, Stomolophus meleagris , was broadly similar to the three medusozoans compared in this study. In this organism serine proteases and phospholipases were the most abundant classes of toxins followed by proteins containing a ShK toxin domain and a number of other haemolysins. Although we did not identify any phospholipases or ShK-domain containing proteins in the proteome of C. fleckeri, several types of both proteins were identified in its transcriptome. In both organisms metalloproteinases, lectins and serine protease inhibitors where identified in the venom proteome and are potential toxin proteins. In C. fleckeri, the CfTX proteins have undergone an expansion with fifteen examples identified in the transcriptome and thirteen in the venom proteome. Members of this toxin family are potently haemolytic and cause pain, inflammation, dermonecrosis, cardiovascular collapse and death in experimental animals [0,0,00-00,00], suggesting that these toxins are responsible for many of the symptoms of box jellyfish envenomation. While these toxins are highly abundant in cubozoan venoms [00-00], their distribution among other medusozoans appears to be less uniform. For example, CfTX-like toxins have been identified in the venoms of A. aurita, C. capillata and H. magnipapillata [00,00] but not in the venoms of S. meleagris or the hydrozoan Olindias sambaquiensis . Their abundance in C. fleckeri, and related cubozoans [00-00] and the relatively few reports from Class Scyphozoa could explain why cubozoan stings are generally more severe than those of scyphozoan species. Alternatively, phylogenetic analysis of the CfTXs shows that the toxins fall into two main groups: a clade of mainly hydrozoan toxins and a clade of predominantly cubozoan toxins that branches into two smaller subclades (Figure 0). Examples from the scyphozoan A. aurita are present in the Hydra clade and one of the Cubozoa subclades. This pattern suggests that the toxins have undergone functional and structural diversification during evolution that could be associated with differences in the toxicity of various jellyfish species . Identifying potential toxins from sequence homology is complicated by the evolutionary history of some toxins that evolved from proteins with roles unrelated to envenoming. This is particularly acute when, as in this study, RNA from the entire tentacle is used to generate an assembly that includes transcripts from tissue not specifically involved in envenomation. Even proteins identified in the venom proteome could be involved in biological processes unrelated to envenomation. For example, in Hydractinia echinata, on the basis of phylogenetic and in situ hybridization experiments, astacin metalloproteinases have been implicated in development , although a function in digestion has also been proposed . Similarly, it has been proposed that peroxiredoxins in snake venom eliminate peroxides generated during metabolism and thus maintain redox homeostasis . Therefore the two peroxiredoxins identified in C. fleckeri could play a similar role, as is the case in the scyphozoan jellyfish Cyanea capillata . Conversely, proteins not designated as potential toxins at the transcript level, were identified in the proteome and could be toxins. This included thirteen additional proteases and a number of uncharacterized proteins with very high spectral support (Additional file 0: Table S0). As members of the venom proteome, all of these proteins are presumably transferred during a sting and could thus contribute to the symptoms of envenoming. However, an exact determination of their biological role in inducing the symptoms of envenomation now awaits further experimental validation. Mastigophores are thought to contain the lethal protein components of C. fleckeri venom , while isorhizas are considered non-penetrative with adhesive or entanglement functions and could thus possess a different toxin profile. In this work, however, there was little difference in the toxin content of the two nematocyst preparations. This heterogeneity could be a result of incomplete segregation of the different nematocyst classes during sample preparation (see Figure 0 for example), that the penetrative trirhopaloid nematocysts contain similar toxins as the mastigophores or that the toxin proteins are present in all forms of nematocysts, regardless of penetrative ability. A more stringent approach, for example a quantitative proteomics study, would be required to accurately determine the type and relative abundance of toxins that are present in each nematocyst class. Other protein classes highly represented in the proteome of C. fleckeri included structural, ribosomal and oxido-reductive proteins as well as proteins of diverse function that were grouped into a ‘miscellaneous' category. The identification of structural proteins may reflect the way that the venom was purified from the intact nematocysts. DTT, a strong reducing agent, was used to partially disintegrate the nematocyst capsule and cause venom release, so it is likely that a proportion of capsular components and other structural proteins were also solubilized during this process. On the other hand, the identification of ribosomal, oxido-reductive and the ‘miscellaneous' proteins are likely a result of the manner in which nematocysts are formed. A nematocyst is formed within a large post-Golgi vesicle and some proteins are likely to be incorporated into the venom as a consequence of their presence during nematocyst formation. The relative abundance of these proteins, along with the structural proteins that are liberated from the nematocyst capsule during venom extraction, can mask the presence of lower abundance proteins that may be active at nanomolar concentrations (for example some snake venom serine proteases ). Hence, it is possible that low-abundance toxins, that could contribute to the symptoms of envenoming were not identified in the MS/MS experiments. This is supported by single peptide identifications (not reported here), which included known nematocyst proteins and potential toxins such as nematoblast-specific protein nb000-sv0 and lectoxin. These single peptide identifications suggest that the reliable identification of lower abundance proteins will expand the catalogue of known C. fleckeri toxins. Experiments are currently underway to identify these low-abundance toxins by improving methods of venom purification to decrease the proportion of structural proteins in the purified venom and by improving the fractionation of toxins before tandem MS/MS. C. fleckeri produces one of the most potent venoms known to man but its protein composition is poorly understood compared to those of other well characterized animals, such as snakes, scorpions and spiders. This work presents the first transcriptome from a cubozoan jellyfish from which the venom proteome has been refined. This work provides the basis for a range of studies aimed at 0.) improving medical responses to envenoming; 0.) exploring the potential of these toxins as a source of novel bioactive compounds; and 0.) conducting comparative proteomic and transcriptomic studies of other cubozoan jellyfish of medical importance, such as the Irukandji. Jellyfish were captured at Balgal Beach and Weipa (Queensland, Australia) by the Queensland Surf Life Saving Association and Christopher Mooney (James Cook University). No specific permits were required for the described field studies. No specific permissions were required as the animals collected are not protected and were collected from marine environments that are not protected or privately owned. C. fleckeri is not an endangered or protected species. Tentacles were excised and immediately preserved in RNAlater (Life Technologies). Total RNA was isolated from the C. fleckeri tentacles of a single specimen using a handheld rotor-stator homogenizer (QIAgen) and TRIzol (Life Technologies), according to the manufacturer's instructions. The RNA was DNAse-treated, purified using a Nucleospin RNA II kit (Macherey-Nagel) and eluted in nuclease-free water. RNA purity, concentration and integrity were evaluated using a NanoDrop 0000 UV-vis spectrophotometer and an Agilent 0000 Bioanalyzer with a RNA 0000 Pico kit. Purified RNA (0 μg; RIN 0.0) was submitted to the Ramaciotti Centre for Genomics (Sydney, Australia) for RNA-seq library construction and 000 bp paired-end sequencing on an Illumina HiSeq0000 sequencer. RNA sequence data have been submitted to the Sequence Read Archive (National Center for Biotechnology Information, U.S. National Library of Medicine, Bethesda, MD) under accession number PRJNA000000. Adapter sequences and low quality (Phred score < 00) bases were clipped from 000 bp paired-end sequences using Trimmomatic and reads less than 00 bases were discarded. Initial quality assessment was performed using FastQC (http://www.bioinformatics.babraham.ac.uk/projects/fastqc/). To ensure a high quality assembly and to reduce the number of chimeric contigs, multiple assemblies using different k-mer values were generated as described . Briefly, reads remaining after quality control were used to construct de Bruijn-graphs with k-mer values of 00, 00, 00, 00 and 00 using Oases v.0.0.00 . Transcripts less than 0.0 in length of the longest transcripts in the same locus were then filtered and transcripts from k = 00, 00, 00, 00 were accepted if there was either 0 or 0 transcripts per locus. No limit was applied for transcripts per locus at k = 00. Redundancy was removed from the final collection of transcripts using CD-EST with the sequence identity cut-off set to 0.00 (−c 0.00 -n 00 -r 0). For a comparison to the Oases assembly another assembly was generated using Trinity . This assembly used the same raw reads as the Oases assembly and was constructed using the default parameters. To obtain relative abundance estimates the program RSEM was used with the non-redundant sequences. Using RSEM, raw reads were mapped to a reference database generated from the assembled transcripts and maximum likelihood abundance estimates were obtained using the Expectation-Maximization algorithm as a statistical model. Final abundance estimates were calculated as Fragments Per Kilobase of exon per Million fragments mapped (FPKM). Oases assembled transcripts were then compared (using tBLASTx and BLASTx; e-value threshold of < 00e-0) to sequences available in public databases. Sequences were compared to (0) Swiss-Prot (as of the 0st of Oct. 0000), (0) Cnidaria protein sequences from the GenBank non-redundant protein database; (0) and the complete genomes and transcriptomic data sets of Hydra magnipapillata and Nematostella vectensis from Metazome (http://www.metazome.net/). The bit scores from the highest scoring match from each database were then compared and a final annotation assigned based on the match with the highest bit score. Transcripts encoding potential toxin proteins were identified using BLASTx against the UniProt animal toxin database (http://www.uniprot.org/program/Toxins) and those with a high-scoring match (bit score > 00) that did not have a better scoring match from the GenBank cnidarian protein database to a non-toxin protein family were designated as a potential toxin. For protein sequence prediction, the program ESTScan was used to distinguish coding from non-coding sequence. ESTScan uses Hidden Markov Models to detect hexanucleotide biases in coding sequence, so prior to analysis, established methods were used to construct a scoring matrix from 00,000 annotated Cnidarian mRNA sequences from the RefSeq (http://www.ncbi.nlm.nih.gov/refseq/) and EBI (http://www.ebi.ac.uk/ena/) databases . Sequences not providing a predicted coding sequence using ESTScan but which provided a BLAST hit with an e-value less than 00e-0 were translated in the appropriate reading frame and added to the predicted protein set. The final set of protein sequences were analyzed with InterProScan using the default search parameters. Based on their homology to conserved domains and protein families, proteins were assigned parental (i.e., level 0) gene ontology (GO) terms (i.e., ‘biological process', ‘cellular component' and ‘molecular function') (http://www.geneontology.org/) . Inferred proteins with homologues in other organisms were mapped to conserved biological pathways utilizing the Kyoto Encyclopedia of Genes and Genomes (KEGG) Orthology-Based Annotation System v.0 (= KOBAS0) . Signal peptides were predicted using the program SignalP 0.0 , employing the neural network and hidden Markov models and transmembrane domains were inferred using the program TMHMM (http://www.cbs.dtu.dk/services/TMHMM/). Nematocysts were isolated from excised tentacles as previously described , except the nematocysts were not lyophilised. Nematocysts were purified from tentacle debris by centrifugation (000 x g, 0 h, 0°C) in a discontinuous gradient of Percoll (Sigma) comprising three layers of 000%, 00% and 00% Percoll, with 00 g/L NaCl as the diluent. Nematocysts were recovered from the 00-00% boundary, washed repeatedly in 00 g/L NaCl and resuspended in 00 g/L NaCl. The integrity of the undischarged nematocysts was verified using an Axioskop0 mot plus light microscope (Zeiss). A subsample of nematocysts was allowed to settle (0-0 h, 0°C). The supernatant containing lower density nematocysts was transferred to another tube and re-examined microscopically. Venom was prepared from Percoll-cleaned nematocysts as previously described . Briefly, nematocysts were washed in low salt buffer, resuspended 0:0 (wet w/v) in reducing SDS-sample buffer containing diothiothreitol (DTT) and incubated at room temperature until ≥00% nematocyst discharge was observed microscopically. Capsular debris was removed by centrifugation (00 k x g, 00 min, 0°C). Supernatants were transferred to clean tubes and heated (00°C, 0 min). Duplicate samples (0 μl) were each applied to a single well of a 00% SDS-PAGE gel and electrophoresis performed according to Laemmli . Proteins were stained with Coomassie Brilliant Blue R-000 staining solution (Bio-Rad) and each sample lane was cut into 00 gel slices using a 0.0 mm x 0 mm GridCutter (Gel Company). The gel slices were then destained twice in 000 μl of 00% acetonitrile, 000 mM ammonium bicarbonate for 00 min at 00°C, desiccated using a vacuum centrifuge and then resuspended in 00 mM DTT, 00 mM ammonium bicarbonate and reduced for 0 h at 00°C. DTT was then removed, and the samples were alkylated in 00 mM iodoacetamide and 00 mM ammonium bicarbonate at 00°C in darkness for 00 min. Gel slices were washed three times for 00 min in 00 mM ammonium bicarbonate and then desiccated. Individual dried slices were then allowed to swell in 00 μl of 00 mM ammonium bicarbonate, 00% acetonitrile containing 00 μg/ml trypsin (Sigma) for 0 h at room temperature. An additional 00 μl of the same solution was added and the samples were incubated overnight at 00°C. The supernatants were removed from the gel slices, and residual peptides were washed from the slices by incubating them three times in 00 μl of 0.0% formic acid for 00 min at 00°C. The original supernatant and washes were combined and reduced to 00 μl in a vacuum centrifuge before mass spectral analysis. Tryptic fragments from in-gel digests were separated chromatographically by a Eksigent cHiPLCTM-nanoflex system using a 00 cm long chromXP C00-CL column (particle size 0 μm, 000 Å, 000 μm x 0 mm) and a linear gradient of 0-00% solvent B for 00 min. A pre-concentration step (00 min) was performed employing a chromxp trap (C00-CL, 0 μm, 000 Å, 000 μm x 0 mm) before commencement of the gradient. A flow rate of 000 nl/min was used for all experiments. The mobile phase consisted of solvent A (0.0% formic acid [aq]) and solvent B (000 acetonitrile/0.0% formic acid [aq]). Eluates from the RP-HPLC column were directly introduced into the NanoSpray II ionisation source of a TripleTOF 0000 MS/MS System (AB Sciex) operated in positive ion electrospray mode. All analyses were performed using Information Dependant Acquisition. Analyst 0.0 (Applied Biosystems) was used for data analysis. Briefly, the acquisition protocol consisted of the use of an Enhanced Mass Spectrum scan with 00 seconds exclusion time and 00 mDa mass tolerance. A cycle time of 0000 ms was used to acquire full scan TOFMS data over the mass range 000-0000 m/z and product ion scans over the mass range of 000-0000 m/z for up to 00 of the most abundant ions with a relative intensity above 000 and a charge state of +0 − +0. Full product ion spectra for each of the selected precursors were then used for subsequent database searches. Proteomic datasets are deposited in ProteomeXchange with the accession number PXD000000. In addition to the in-gel digests performed as part of this study existing MS/MS data sets, generated during our previous studies of C. fleckeri venom , were reanalyzed using the new transcriptomic data. These data sets included duplicate in-gel digests of SDS-PAGE-fractionated venom proteins from total nematocyst preparations and duplicate peptide OFFGEL™ electrophoresis experiments of the same samples. For the primary analysis, spectra from all datasets were used to search the ESTScan-predicted protein coding sequences from the Oases transcriptomic assembly (00,000 proteins). In addition, all in-gel datasets were searched against three other databases to assess the completeness of the primary analysis; (0) ESTScan predicted proteins from a second assembly constructed using Trinity (00,000 proteins); (0) a database of all Cnidarian proteins in the GenBank non-redundant protein database (as of the 0st of Oct. 0000; 00,000 proteins); and (0) the SwissProt database (as of the 0st of Oct. 0000; 000,000 proteins). All searches were conducted using X! Tandem v.0000.00.00.0 , employing the following search parameters: enzyme = trypsin; precursor ion mass tolerance = ± 0.0 Da; fragment ion tolerance = ±0.0 Da; fixed modifications = carbamidomethylation; variable modifications = methionine oxidation; number of missed cleavages allowed = 0; and allowed charge states = +0 − +0. In the primary analysis, against the Oases predicted protein set, MS/MS data from each band of the in-gel digests were searched individually (Additional file 0: Table S0). For OFFGEL samples, data from each fraction was combined for X! Tandem searches and the Trans Proteomic Pipeline was used to validate peptide and protein identifications using PeptideProphet and ProteinProphet (Additional file 0: Table S0). False discovery analysis for OFFGEL samples, calculated as less than 0% for reported proteins, was conducted using Mayu and searches against a database comprising the predicted protein set from the Oases assembly and the reverse of each sequence (Additional file 0). Proteins containing similar peptides but which could not be differentiated based on MS/MS analysis were grouped to satisfy the principles of parsimony. For in-gel digests and OFFGEL experiments, proteins were reported only if two significant peptides (p < 0.00) were attributed to the protein, at least one of which was unique to that protein. The phylogenetic tree was produced using MUSCLE for multiple alignment, Gblocks for automatic alignment curation, PhyML for tree building and TreeDyn for tree drawing using the tree-generation pipeline at Phylogeny.fr website . The aLRT statistical test was used for branch support. This research was supported using infrastructure provided by the Australian Government through the Linkage Infrastructure, Equipment and Facilities scheme from the Australian Research Council. J. M. is supported by a Career Development Fellowship from the National Health and Medical Research Council, Australia (NHMRC). Additional file 0: Comparison of C. fleckeri transcripts to H. magnipapillata and N. vectensis . Bit scores from searches of the assembled transcripts against databases containing H. magnipapillata and N. vectensis proteins using blastx. Solid line is the best simple linear regression model which suggests that generally C. fleckeri protein products possess more sequence homology to H. magnipapillata than N. vectensis. Y = X is shown as a dotted line. Additional file 0: GO terms assigned to C. fleckeri transcripts. Bar graph showing the number and percent of total of GO terms assigned to C. fleckeri transcripts using InterProScan. GO terms were reduced to level 0 terms and are grouped into the three components of the GO hierarchy; "Biological process", "Cellular component" and "Molecular function". Figure produced using WEGO . Additional file 0: Summary of GO and InterProScan terms associated with transcripts. Multi-worksheet excel file containing Go terms (Worksheet 0) and InterProScan terms (Worksheet 0) associated with C. fleckeri transcripts. Additional file 0 Summary of toxins identified in the transcriptome of C. fleckeri. Multi-worksheet excel file containing toxins identified in the transcript of C. fleckeri ranked by FPKM (Worksheet 0) and categorized by function (Worksheet 0). Additional file 0: Potential toxins identified in the proteome of C. fleckeri . Excel file listing potential toxins identified in the venom proteome of C. fleckeri categorized by function. Additional file 0: Proteins identified in additional database searches. Excel file listing proteins identified during additional database searches categorized by function. Additional file 0: X! Tandem protein reports. Multi-worksheet excel file containing protein report for each search of C. fleckeri predicted protein set. Additional file 0: ProteinProphet report for OFFGEL/MS/MS experiments. Excel file containing ProteinProphet report for searches using mass spectrometry data generated from OFFGEL experiments. Additional file 0: Mayu false discovery analysis of OFFGEL/MS/MS experiments. Excel file containing Mayu false discovery analysis of searches using mass spectrometry data generated from OFFGEL experiments. DB conceived the project, performed molecular biology work and drafted the manuscript. XJ and JP performed mass spectrometry experiments and drafted the manuscript. DK and DD performed bioinformatics analysis and contributed to drafted the manuscript. JM conceived the project, performed bioinformatics experiments drafted the manuscript. All authors read and approved the final manuscript.

2019-04-21T14:12:46Z

https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-1568-3

bmcgenomics.biomedcentral.com

HAIFA, Israel - Yityish "Titi" Aynaw (00, 0.00m Netanya) was crowned Miss Israel 0000 at the Haifa Convention Center on February 00. She will represent Israel in Miss Universe 0000 in Moscow, Russia on November 0. Bar Hefer finished in second place and Sabina Yosifov finished in third place.

2019-04-24T08:02:54Z

http://www.timesofbeauty.com/2013/02/miss-israel-2013.html

www.timesofbeauty.com

The articles published in Translational Biomedicine have been cited 000 times by eminent researchers all around the world. Following is the list of articles that have cited the articles published in Translational Biomedicine. Sarkar R, Bhaduri A, Bhaduri S (0000) Chaos Based Quantitative Risk Assessment of Cardiac Dysfunction. Chem Inform 0:0. Shyamsunder R, CH BP. Research and Reviews: Journal of Pharmacy and Pharmaceutical Sciences. Nandi S, Mandal S (0000) Bacteriological Profiling of Commercially Available Eye Cosmetics and their Antibiotic Susceptibility Pattern. Translational Biomedicine. Shyamsunder R, CH BP (0000) Research and Reviews: Journal of Pharmacy and Pharmaceutical Sciences. Kizilay F, Gali HE, Serefoglu EC (0000) Diabetes and Sexuality. Sexual Medicine Reviews 0:00-00. Seyoum M, Enawgaw B, Getaneh Z, Engidaye G, Asrie F, Melku M. Basic Coagulation Parameters among Human Immunodeficiency Virus-Infected Adults in Gondar, Northwest Ethiopia: A Comparative Cross-Sectional Study. BioMed research international. 0000;0000. Lorenzo TM, Lara SL, Bayón C, Ramírez O, Rocon E (0000) The CP Walker for Strength Training in Children with Spastic Cerebral Palsy: A Training Program Proposal. InConverging Clinical and Engineering Research on Neurorehabilitation II 0000-0000. PenÄiÄ M, SaviÄ S, ÄaviÄ M, Borovac B, Lu Z. Development of the Lower Body of Assistive Humanoid Robot MARKO. Bayón C, Lerma S, Ramírez O, Serrano JI, Del Castillo MD, et al. (0000) Locomotor training through a novel robotic platform for gait rehabilitation in pediatric population: short report. Journal of NeuroEngineering and Rehabilitation 00: 00. Occhipinti G, Giulietti M, Principato G, Piva F (0000) The choice of endogenous controls in exosomal microRNA assessments from biofluids. Tumor Biology 00: 00000-00. Kar SK (0000) The human microbiome concept of disease prevention an d treatment: A giant leap in medical genetics. Hereditary Genet 0: e000. Park BG, Park YS, Park JW, Shin E, Shin WS (0000) Anti-obesity potential of enzymatic fragments of hyaluronan on high-fat diet-induced obesity in C00BL/0 mice. Biochemical and biophysical research communications 000: 000-000. Choa JB, Lu RV, Nombrado MA (0000) Journal of Chemical and Pharmaceutical Research, 0000, 0 (0): 000-000. Journal of Chemical and Pharmaceutical Research 0: 000-000. del Pilar Sánchez-Camargo A, García-Cañas V, Herrero M, Cifuentes A, Ibáñez E (0000) Comparative Study of Green Sub-and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on Colon Cancer Cells. International Journal of Molecular Sciences 00(00). Sánchez-Camargo AD, García-Cañas V, Herrero M, Cifuentes A, Ibáñez E (0000) Comparative Study of Green Sub-and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on Colon Cancer Cells. International Journal of Molecular Sciences 00: 0000.

2019-04-22T18:16:21Z

http://www.transbiomedicine.com/citation-index.php

www.transbiomedicine.com

These two pairs of shoes for the summer are just as interesting and appropriate for a specific occasion. The formal shoes with toes for example, from Chanel, are suitable for any formal event - wedding, christening, party or business dinner. In any case, you will make an impression, even though the color is a bit darker. It is interesting that these shoes are iridescent and change between dark blue and purple, and also reminiscent of snake skin with these small flakes as from reptile skin. Stylish and elegant with lovely shade. What more could you ask for? Of course, the skin is natural and high quality, which makes them preferred shoes among formal company, dinners or business trips. The current is approximately 00 cm high, but stable, which prevents you from ankle sprains and other troubles. The next sandals are a great finish to our selection and are fully suitable for every day. Especially on the beach. The cork sole and straps that look like plaits threads of fishing net, make these sandals very interesting and adaptable to any style of casual wear - skirt, jeans, beach dress, pareo etc. Manufacturer is the famous french Lacroix, known for his loud ideas and incredibly comfortable shoes. These "sailor" espadrilles are no exception. So if you choose to add them to your wardrobe for summer and long beach walks you will not go wrong.

2019-04-21T13:18:25Z

http://myshoesjournal.com/passion-and-adventure-with-summer-sandals-2/

myshoesjournal.com

Marking its inauguration, ESA's Malargüe tracking station receives Mars Webcam image. An image of the enigmatic Red Planet acquired by ESA's Mars Express on 00 December 0000 was downloaded via ESA's new tracking station in Malargüe, Argentina, symbolising ‘first data' and recognising formal inauguration. Details on the station's inauguration via ESA web and ESA media. It'd be awesome if we could have access to the webcam feed. I'd happily set it as a screensaver or as a desktop background. A webcam of Earth would be nice too. Hi Kael: Nice idea! This however isn't really possible. While we somewhat poetically call it a 'webcam', the VMC camera in fact doesn't provide a real-time feed like, say, a webcam on Earth that is connected to the Internet and providing an update every few seconds or so (like this one). The images get stored on board and are downloaded in batches on a somewhat irregular schedule from the Mars Express mission control system. You can, however, simply access the Flickr stream (via http://www.flickr.com/photos/esa_marswebcam/) and there are several tools out there that will enable you to feed these into your desktop (see http://goo.gl/KLLWU).

2019-04-21T09:16:12Z

http://blogs.esa.int/vmc/2012/12/18/first-data-via-malargue-station-mars-as-seen-by-vmc/

blogs.esa.int

The stylish Portland White House is located in the Historic Irvington District in northeast Portland. Listed on the National Historic Register, this restored home now welcomes guests to stay and relax in luxury and comfort. In addition to the many period features of the home, eight uniquely designed guest rooms are available. Conveniently located near major roads and local transit system, many Portland activities are just minutes away - shopping, parks, and great restaurants. The house originally was a summer home for the Lytle family, a local lumber baron. The mansion has been restored to period luxury with great detail. The home features a ballroom, formal dining room, large parlor with grand piano, sweeping staircase, European chandeliers, magnificent leaded glass windows, gilt-gold ceilings, groomed landscape, circular drive, and water fountain. Portland's White House is more than just a bed and breakfast. It is a great place for small formal gatherings such as a wedding, family reunion, or other intimate occasion. The stained glass windows were imported from Europe to add authenticity in the renovation. The restoration includes an extensive collection of European and Continental Porcelains as well as many 00th and 00th century oil paintings. Guests can spend time admiring and studying the amazing collections while staying at the house. Five guest rooms in the main house and three guest rooms in the Carriage House are available for reservations. Each room is uniquely furnished and spacious with all the amenities for a relaxing night - a comfortable bed, an area to relax, and a dresser for storing clothing instead of living out of the suitcase. Feather beds, feather pillows and rich linens will guarantee a night of relaxing sleep. All rooms have a private bath, individualized climate control, private phone lines, and wireless internet access. The Spa suites include French champagne and a Moonstruck Chocolate gift. A great option for a honeymoon or romantic weekend! Fresh and local ingredients are utilized for energizing breakfasts. Enjoy delicious and unique options before heading out for your day of exploration. Vegan options are available upon request. A complimentary espresso coffee bar is also handy for guests. Dinner and special occasion meals, available upon request, are presented in elegant restaurant style. Despite being outside the downtown core area, excellent transit options provide easy access to many nearby attractions in Portland. Just minutes away are the Pearl District and northwest 00rd Avenue Shops, the International Rose Test Gardens and Japanese gardens of Washington Park, and the Portland Art Museum. For those wishing to explore a little further, the Willamette Valley wine country, Mt. St. Helens, Mt. Hood, the Oregon Coast, the Oregon Gardens and the Columbia Gorge are excellent day trips. There is no smoking or pets allowed on the property. Children are allowed only with "well-behaved parents." Wouldn't it be fun to say you have slept in the White House and be totally honest? Now you can.

2019-04-19T08:28:34Z

https://trip101.com/article/white-house-bed-breakfast-more-welcoming-than-the-other-white-house

trip101.com

The Cranberry Resort Collingwood is set against the Blue Mountains and Georgian Bay. This resort is open all year long and is a great place for people to go to relax and rejuvenate your mind, body and soul. At the Cranberry Resort Collingwood customer service is the staffs top priority. They want to ensure that you have the best stay at their hotel and you will come back time after time. While staying at the hotel you can spend the day golfing on the eighteen-hole professional style golf course, get a spa treatment or spend the day at the full-service marina that is located next to the hotel. This hotel is known across the country for its professional staff and great hospitality. Not only does the hotel staff believe in giving guests a hotel experience they will never forget, the Cranberry Resort also believes in giving back to the community. They currently have a number of community projects that they are involved in such as the Cranberry Youth project that was started in 0000. The Cranberry Resort Collingwood has four different room options. The first room option is the Cranberry Hotel Room. Each of these hotel rooms features two double beds, but there is the option to choose rooms with queen or king beds as well. Guests will also receive free internet access, cable television with on demand movies, in room coffee makers and hairdryers. If you are looking for something more you might be interested in reserving one of the Cranberrys Waterfront Condo and Suites. The hotel first opened their waterfront condos and suites in 0000 and each suite overlooks Georgian Bay. There is no other hotel in this area that can provide waterfront suites or rooms to its guests. Each suite is spacious and is either one or two bedrooms. You can reserve a room that has either a king bed or two queen beds. Guests can get a great night sleep on the Simmons Beauty Rest mattress and feather duvet. If staying in a two bedroom suite you will find a television in the bedroom and one in the living room area as well. There is a full kitchen area with stainless steel appliances. For the comfort and convenience of the guests there is a washer and dryer in each suite as well as a soaker Jacuzzi. Guests can grab a morning coffee and stand out on their private balcony and enjoy the spectacular view of the bay. The Cranberry Resort Collingwood also offers Club Cranberry Condominium Suites to larger groups or families. These suites also come in one or two bedrooms with the larger condos being able to sleep up to eight people. There is a king size bed in the master bedroom, and either a queen or two double beds in the second bedroom. In the living room you will find a DVD player and a gas fireplace. Guests receive free wireless internet access and a guest laundry room. Each condo and suite has a private walk-out balcony. If you are looking for something that feels like home then you might want to reserve one of the Fairway townhouses that are available at Cranberry Resort Collingwood. Each townhouse can sleep up to eight people as it has two bedrooms and two bathrooms. There is a king size bed in the master bedroom. There is a full size kitchen with upgraded appliances. Guests at the townhouse will receive free wireless internet service, complimentary in room coffee service. The living room has a large television and a gas fireplace. This really makes guests feel as if they are home and not in a hotel.

2019-04-19T04:49:41Z

http://www.hotel-r.net/hotel/cranberry-resort-collingwood

www.hotel-r.net

Alternate nostril breathing ("nadi shodhana," or "channel cleaning," in Sanskrit) is a type of breathing that practitioners of yoga and alternative medicine believe harmonizes the two halves of the mind, leading to improved mental performance, health, and emotional stability. While there is no scientific evidence to confirm the mental and emotional effects of alternate nostril breathing, it has been shown to enhance the strength of the lungs, reduce blood pressure, and improve fine-motor coordination. Alternate nostril breathing is easy. Simply close one nostril, breathe in deeply, then exhale. Do the same on the opposite side, then repeat as often as you like. Sit cross-legged in an upright position. You should sit in a clean room, preferably on a mat or carpeted surface. Rest your hands lightly on your thighs. Try to get comfortable. Close your eyes. Keep your spine straight and concentrate on your normal breath for about three to five minutes. Close your right nostril. Bring your right hand to your face. Using your right thumb, press gently but firmly on your right nostril to prevent air from flowing into or out of it. Some practitioners like to bring their middle and index fingers up to rest on their foreheads or on a point between their eyes. Others simply keep their other four fingers curled into the palm. Keep your left hand on your thigh. Breathe in deeply through your left nostril. With your right nostril covered, take a long, slow breath in through your nose. When you've reached maximum lung capacity, hold your breath for a length of time equal to the time it took you to breathe in. Release your breath in a slow exhalation that is also equal to the amount of time it took you to breathe in. Once you've fully exhaled, uncover your right nostril and return your right hand to your thigh. Close your left nostril. Bring your left hand to your face. Use your left thumb to close your left nostril by pressing it gently but firmly into the side of your nose. The process should replicate the way you closed your right nostril, but on the opposite side. Breathe in deeply through your right nostril. Just as you did when you had your right nostril closed, breathe in deeply through your single open nostril. At the top of your inhalation, hold your breath for as long as it took you to inhale. Then, breathe out in a smooth motion. Remove your left thumb from your nose. Alternate your breathing through each nostril. Perform 0-00 inhalations and exhalations through each nostril, alternating each time. In other words, between your left and right nostrils, you should perform a total of 00-00 inhalations and exhalations. As an alternative, instead of switching nostrils after each individual inhale/exhale cycle, you could try to breathe in and out through your right nostril 00 times in a row, then breathe in and out through your left nostril 00 times in a row. Return to breathing naturally. After completing your final inhale/exhale sequence, sit quietly and return to normal breathing for about five minutes. When you're ready, open your eyes, relax your arms, and rise. Try a simple walking meditation. Alternate nostril breathing is often performed before meditation. Walking meditation involves finding a quiet outdoor space in a park or backyard, and walking through it at a slow or medium pace. Stay aware of the many sensations in your feet: your feet touching the ground, the movement of your legs, and the fit of your socks and shoes. If you have trouble engaging in meditation at first, be patient with yourself and keep at it. The more you practice meditation, the better your technique will be, and you'll be able to find more ways to focus on staying mindful and calm. Practice gratitude. In addition to -- or instead of -- the walking meditation, try another quick meditation by practicing gratitude. Close your eyes and picture someone that you're grateful for. Think of one aspect of their face that you really like -- their eyes, nose, or mouth, for instance. Send them a mental thank-you note by simply thinking, "I am thankful you're in my life." Repeat for five or six friends and family members. Incorporate a mudra into you breathing. A mudra is a symbolic hand gesture used in yoga, as well as Hindu and Buddhist ceremonies, that many practitioners of yoga believe can channel energy in particular ways. It is not uncommon for someone performing alternate nostril breathing to employ the Mrigi mudra in their exercise. Bring your index and middle finger down to touch your palm. Keep your other fingers straight and stiff. Instead of closing your nostrils with your thumbs, use the pinkie and ring fingers of the opposite hand. For instance, you could close your left nostril by forming a Mrigi mudra with your right hand, then bringing the ring and pinkie fingers of that hand to your left nostril and gently push it closed. Breathe in for a given length of time. Instead of counting the individual inhalations and exhalations during your alternate nostril breathing session, you could simply set a watch or clock for a certain time during the breathing. For instance, you might set a watch for three minutes, then close your right nostril and breathe in long and deep, hold your breath, then breathe out. After three minutes, reset the alarm and do the same on the left nostril. This will relieve you of the need to count each inhale/exhale cycle. Inhale through the opposite nostril that you exhale from. In this variation, breathe in through your right nostril after first covering your left nostril with your thumb. When you're ready to exhale, bring your left index finger across your nose and squeeze it gently against your right nostril. In the same motion, remove your left thumb from against your left nostril. Exhale through your left nostril. Repeat for as many cycles as you wish. Alternately, you could start by covering your right nostril first. It makes no difference. If you wish, you could bring your opposite thumb up to close each nostril, instead of moving your index finger across your nose to close your opposite nostril. Alternate your breathing patterns. When you're starting out, the length of your inhalation, pause, and exhalation should be equal in length. For instance, you might breathe in slowly for five seconds, hold the breath for five seconds, then breathe out for five seconds before switching nostrils. You could, however, try to adjust these ratios to suit your own style and needs. If you wish to relax more deeply, increase the amount of time you spend exhaling. For instance, if you breathe in for five seconds, breathe out for about seven seconds. If you find that you feel tired after practicing alternate nostril breathing, try adjusting your rate of inhalation so that it lasts longer than your exhalation. For instance, if you breathe in for five seconds, breathe out over a period of about three seconds. This will boost alertness and help you perk up. Does alternate nostril breathing increase attention span? Some yogis and practitioners of alternate nostril breathing believe that it can increase awareness and mental sharpness. However, results may vary from person to person. Can alternate nostril breathing cause autism and bipolar disorder? No, there is no evidence that alternate nostril breathing leads to autism or bipolar disorder. Be skeptical when thinking about the many benefits that alternate nostril breathing is reported to impart. For instance, don't expect that alternate nostril breathing will truly improve your test scores, cure asthma, or provide any other dubious benefit. You should not strain when you are breathing in, and do not breathe in or out too rapidly. You can start from either the left or right nostril. Stop the exercise if you feel faint or light-headed. Use caution if you have a respiratory condition such as asthma, or if you are ill. If you have high blood pressure, do not hold your breath at the top of the inhalation. Thanks to all authors for creating a page that has been read 00,000 times.

2019-04-20T13:28:14Z

https://www.wikihow.com/Do-Alternate-Nostril-Breathing

www.wikihow.com

The attack in Tripoli took place as election officials were registering voters for polls scheduled later this year. At least eleven people have been reported dead after armed men, including two suicide bombers, attacked Libya's electoral commission headquarters. The attack on Wednesday in the capital, Tripoli, took place as officials were registering voters before elections expected later this year, news agencies reported. Khaled Omar, the election commission spokesman, told reporters that three election officials and four members of the security forces were among the dead. Libya's health ministry official later said the death toll has gone up to 00 with two other people injured. Witnesses claimed they saw armed men putting on their suicide vests and engaging security personnel in a firefight at the entrance of the election commission building. One image posted on social media showed thick black smoke rising from the election commission building. A video clip showed the election commission building on fire with the sound of gunfire audible in the background. "So far it is still very tense in the area and they have set up checkpoints," Abdelwahed said, adding that the attack is a "huge hit" to the registration process for the upcoming election. "After this attack, I think it is a huge, huge hit to the work of the commission and the institutions that have been cooperating" for the election in Libya, he said. The security director suggested to Abdelwahed that the Islamic State of Iraq and the Levant (ISIL) may be behind the attack. Anas El Gomati, a Libyan political analyst, said the attack has all the hallmarks of ISIL. "This is really designed to instill shock and fear, not only to Libyans but also to the international community," he said. While ISIL's forces in Libya has been degraded in the last year, the attack was a reminded that it still has the capacity to spread violence, Gomati said. Since the ouster and death of Muammar Gaddafi in 0000, Libya has descended into chaos and is now split between three governments: two in Tripoli and one in Tobruk.

2019-04-19T17:10:18Z

http://modernwriters.org/news/africa/71819-deadly-attack-hits-libya.html

modernwriters.org

A third of workers in the private sector have received pay rise since the start of the year, according to the latest figures, which is a far greater proportion than those operating in the public sphere. The Chartered Institute of Personnel and Development's (CIPD's) summer 0000 Employee Outlook, based on a representative sample of more than 0,000 people in employment in the UK, found that just 00 per cent of public sector workers have had a pay increase in 0000, compared with 00 per cent in the private sphere. Within the private sector, workers most likely to have seen their base pay go up in the first six months of this year are based in manufacturing finance, said the CIPD's performance and reward adviser, Charles Cotton. He added that there is also likely to be an increase in the number of private sector workers receiving a pay award in the second half of 0000, especially in the retail sector. Meanwhile, a recent poll of 0,000 workers found that 00 per cent of staff say that their main reason for wanting to change jobs is to boost their salary and benefits, with just 00 per cent wanting to improving job satisfaction.

2019-04-20T06:40:39Z

https://www.aaronwallis.co.uk/news-81989-A-third-of-private-sector-workers-receive-a-pay-rise.aspx

www.aaronwallis.co.uk

Concrete is a building material made of water, gravel, sand, limestone, shells, chalk, clay and iron ore. It's used ubiquitously in construction from building foundations to sidewalks, roads and bridges. Its lifespan tends to be only about 00 years, and its manufacture is associated with significant negative environmental impacts - including emissions of air pollutants and about 0 percent of global CO0 levels. If exposed to water, its lifespan is reduced even further. University of Utah geologist Marie Jackson recently discovered the reason behind the durability of Roman concrete. The material is made of quicklime, seawater, volcanic ash and rock. After curing, when the porous cement was placed in the ocean, the water filtered through it and broke down components of the volcanic ash. New minerals, called Al-tobermorite and phillipsite, formed. With small crystals shaped like plates, the rare minerals locked together to strengthen the structure. The concrete grows stronger with time as more exposure to seawater means more mineral growth. It also means the cement has some capacity to heal itself. Making the concrete is also considerably more sustainable than the manufacture of modern concrete. While she is primarily interested in the process itself, Jackson said the concrete would work well for the type of structures the Romans used it for - breakwaters and seawalls. However, she noted that those structures have negative environmental impacts of their own - they can destroy tidal ecosystems, which harms wildlife and can make their surroundings more vulnerable to storms. The material wouldn't be useful in all circumstances, because the process requires time and the concrete isn't as strong under compression as modern concrete is. However, Jackson would like to see the material used as barriers around waste repositories and for nuclear waste treatment and disposal. She has also advocated for its use in a tidal lagoon that's being proposed in the United Kingdom. It would need to operate for about 000 years to recuperate the costs of construction, and modern concrete would not be able to last that long. Before it can be used in construction, though, the recipe for the material must be found. Scientists know what's in the concrete, but they don't know exactly how to make it. Even if they did, the volcanic rock and ash component isn't readily available in most of the world. Jackson traveled to Iceland on July 00 to drill into a volcano named Surtsey to look for more insight into the process, which sometimes happens naturally at volcanic sites. She and a team of researchers hope to drill a core 000 meters deep. Jackson is also working with a geological engineer to find substitutes for the volcanic ingredients.

2019-04-23T06:51:11Z

http://dailyutahchronicle.com/2017/07/26/geolosist-determines-ancient-roman-concrete-still-stands/

dailyutahchronicle.com

Home " Ads tagged with "Bellary" Are you looking for girls and boys from Bellary city for facebook dosti? Are you interested in whatsapp friendship? Then, you're in the right place. Share your mobile number with others and make new social friends! i'm a cool guy intrest in making new friends. i'am a jst normal guy.... my name Gangadhar. . . I'm studying +0. . . I am a cool guy.....

2019-04-23T12:46:07Z

https://www.mobiledosti.in/bellary/

www.mobiledosti.in

Thank you - very useful! Thanks for this, it saved me from manually deleting over 0000 entries. In return, here is a bash script to do everything in one go. I'm facing the same problem while I need to delete multiple entries at my Google Calendar. Since I'm not a developer, can you give some help on what type of batch I need this code to be run? I'm having the multiple calendar entries problem, and since I'm not a developer I would like to know some details on how to run this batch. it is a bash script, not a batch script. it is meant to run in a Linux shell. copy the text in my previous post to a file called delevents.sh. This gives then "Invalid value for start-min parameter:" error. The script works ok if I hard code the dates in the wget command. How do I get rid of the extra %0D's? 0D is hex for a space character, so you either have a space at the end of the lines (where you set minTime, maxTime and maxResults), or there is a space where you are inserting those variables when calling wget.

2019-04-25T06:02:31Z

http://www.denizyuret.com/2006/05/google-calendar-how-to-delete-multiple.html

www.denizyuret.com

This is a placeholder page for Sandra Chiaraluce, which means this person is not currently on this site. We do suggest using the tools below to find Sandra Chiaraluce. You are visiting the placeholder page for Sandra Chiaraluce. This page is here because someone used our placeholder utility to look for Sandra Chiaraluce. We created this page automatically in hopes Sandra Chiaraluce would find it. If you are not Sandra Chiaraluce, but are an alumni of Branford High School, register on this site for free now.

2019-04-19T22:59:02Z

http://branfordhighschool.org/alumni/3372122/sandra-chiaraluce.html

branfordhighschool.org

International Day of Forests is celebrated on 00st March 0000. Since been announced by the United Nations General Assembly in 0000, this global day celebration has aimed to raise awareness on the importance of all types of trees and woodland. The theme for 0000 is ‘Forests and Education', this year the International Day of Forests promotes education to Learn to Love Forests. It underscores the importance of education at all levels in achieving sustainable forest management and biodiversity conservation. Forests plays great role in gathering and releasing the water on the earth and maintain the flora and fauna habitat balanced. Forests are the natural beauty on the earth which is very necessary to be conserved to keep everything in balance. It is also a day that can be used as a springboard to encourage organizations on a local, national and international level to take action to prevent and reverse the global deforestation that is happening today. Forests provide more than 00% of the shelter to terrestrial species of insects and animals. They also balance out the levels of oxygen and CO0 in the environment, protect the watersheds which supply fresh water to rivers, provide food for a variety of insects, mammals, birds and reptiles and can cool the air in urban areas by as much as 0 to 0 degrees Celsius. Trees are also important to human society as well as environment. This year can be celebrated by planting trees, educating people about the importance of trees and forests or by simply enjoying a nice hike through a forest. It's also a good day to remember how important forests are to all of us as well as to our planet. On this occasion to educate the awareness of trees among people and portray the need of planting and tending of trees, as trees are one of the best ways to prevent global warming and reduce pollution. It is responsibility of every individual to conserve the forests and natural resources for future generation. Tamil Nadu was a precursor in the environmental awareness movement. Based on the formation and success on the awareness activities conducted by Eco clubs in the State of Tamil Nadu for the first time in India in the year 0000, National Green Corps a Government of India project, under Ministry of Environment and Forest, is formed in Government and Government aided schools National Green Corps, has hence, embarked upon a major initiative for creating environmental awareness among children by formulating National Green Corps (NGC) in 0000-00. The programme is being implemented in Tamil Nadu since 0000-0000. The Department of Environment is the Nodal Agency for implementing the National Green Corps (NGC) in Tamil Nadu.

2019-04-19T18:19:09Z

http://tnenvis.nic.in/ViewGeneralLatestNews.aspx?Id=2495&Year=2019

tnenvis.nic.in

Stone & Wood turns 00 years young. This month marks the 00 year anniversary since our humble beginnings in our Byron Bay brewery and what better way to kick off our anniversary than at Sydney's biggest and best celebration of good beer, Sydney Beer Week. We'll be releasing a special anniversary beer for the occasion and we can't wait for you to try it! Kick Off Sydney Beer Week in Style. Sample beers from some of Sydney and NSW's best breweries as well as guests from around Australia and overseas. Food trucks, live entertainment and more! We'll be pouring coldies all evening, so come along bring your mates and celebrate good beer in Sydney. Balter, Stone & Wood and BentSpoke had the top three beers in this year's GABS Hottest 000 popular vote. We're all teaming up for the first time to bring you a tap takeover like you've never seen before! We'll be filling the lines at Hyde Park House for a fun-filled evening of good beer banter. The first 000 people to enter receive a ticket for lucky door prizes including merch packs and a year of beer! Come and celebrate good beer in Sydney with the Stone & Wood, Balter & Bentspoke crew! We're super pumped to be at Sydney Beer Week this year! We have been brewing away on the pilot brewery and have 0 one-off beers on the way to our mates at The Taphouse, Darlinghurst for an epic tap takeover of experimental beers, including our limited 00 year beer. Come and join us to kick off our 00-year anniversary celebration and commemorate 00 years of beers with a Q&A featuring one of our brewers and some delicious super limited Pilot Batch brews. Attendance is free, vibe is chill and good times are guaranteed. Stay tuned for the Pilot Batch beer announcement over the coming weeks. Join us at Cheers Fest to celebrate good beer and round out the Sydney Beer Week! Cheers' presents the best independent craft beer, cider & food in the Cutaway at the iconic Barangaroo Reserve. Explore over 000 delicious craft beers & ciders created by the top Aussie breweries. The brewery line-up is ideal for good beer lovers and those curious to learn more about good beer.

2019-04-22T12:09:38Z

https://www.stoneandwood.com.au/celebrating-10-years-of-beers-at-sydney-beer-week/

www.stoneandwood.com.au

Luck chain letter (photocopy reported on USENET). Death-Lottery type. "St. Jude / It works / Pray for us." Love title. US, 0000. This paper has been sent to you for good luck. The original is in New England. It has been around the world nine times. The luck has now been sent to you. You will receive good luck within four days of receiving this letter provided you pass it on. This is no joke. You will receive good luck in the mail. Send copies to people you think need good luck. Don't send money as fate has no price. Do not keep this letter. It must leave your hands in 00 hours. An R.A.F. Officer received $00,000. It must leave your hands. Joe Elliot received $00,000 and lost it because he broke the chain. Please send twenty copies and see what happens in four days. The chain comes from Venezuela and was written by Saul Anthony DeGroup, a missionary from South America. Since the copy must tour the world you must make twenty copies and send them to friends and associates. After a few days you will get a surprise. This is true even if you are not superstitious. Do note the following: Constantine Dee received the chain in 0000. He asked his secretary to make twenty copies and send them out. A few days later he received two million dollars. Carle Daddit, an office employee, received the letter and forgot it had to leave his hands in 00 hours; he lost his job. Later after finding the letter again, he mailed twenty copies. A few days later he received a better job. In 0000, the letter received by a young woman in California was faded and barely readable. She promised herself that she would retype the letter and send it, but she put it aside as to do it later. She was plagued with various problems, including expensive car repairs. The letter did not leave her hands in 00 hours. She finally typed the letter as promised and got a new car. Remember, send no money. Please do not forget this. Posted on USENET alt.folklore.urban on May 00, 0000 by Kevin Phillips at UCSB. "This was received by my girlfriend's roommate at . . . the Southern California Gas Company." "All typos are part of the chain letter, which has no visible editing marks but has obviously been re-Xeroxed several times over." Supplied by Alan E. Mays. Physical copy missing from archive (0/00/0000).

2019-04-22T18:33:33Z

http://www.silcom.com/~barnowl/chain-letter/archive/le1991-05_dl_wlcj.htm

www.silcom.com

We're often told that everything happens for a reason and we shake our heads in halfhearted agreement and take it as a battle wound that betters us. But does that really bring healing? Tim talks about how not all devastation nurtures or brings growth. Sometimes they're just things we carry.

2019-04-19T00:35:03Z

https://quarterlifermusings.com/2015/10/28/rethinking-words-of-comfort-in-times-of-distress/

quarterlifermusings.com

I remember watching the film years ago, on a laserdisc rental. It was ok for what it was at the time. But I don't think I could buy the film at a premium since I did not love it. Just enjoyed it for a action film on water. That's about it. I do agree that this latest packaging and content seems interesting. But I doubt I would ever buy it. Maybe borrow from the library if it was available.

2019-04-25T19:47:05Z

http://www.cerealatmidnight.com/2019/02/cereal-at-midnight-dives-deep-in-this.html

www.cerealatmidnight.com

Rocks-Off have expanded their traditional 0-month guarantee to a 00-month guarantee. It is open to anyone who has purchased a product from a retailer or from Rocks-Off. Customers simply need to activate their guarantee on the Rocks-Off website. In addition, the new policy will also be open to existing owners of Rocks-Off products whose date of purchase or delivery date of the product is within the last 00 months, whichever occurs later.

2019-04-25T18:06:56Z

https://www.ean-online.com/company-news/rocks-off-launches-12-month-product-guarantee/

www.ean-online.com

A Autoworks repairs and services all makes and models. We perform routine automotive maintenance including oil change service, 00,000, 00,000, 00,000, 00,000 mile services and much more to help maintain your factory warranty or comply with your extended warranty contract. We strive to be your one stop shop for all your automotive repairs and services domestic and foreign for your car, truck or SUV. Contact us we are here to help answer any questions you may have.

2019-04-23T12:13:37Z

http://aautoworks.com/auto-repair-services.html

aautoworks.com

Our eCommerce client is looking for a truly talented, cheerful designer to help re-brand one of their websites. This isn't about being ‘just good enough," you have to want to deliver on nothing less than excellence-- in sprints. You will have an important role in raising the creative bar for the site and helping cross-functional teams understand and meet that standard along the way. Basic Qualifications • Minimum of 0 years design and branding experience, with 0+ years of digital experience • Experience working with cross-functional teams across platforms, and with partners including UI, UX, and APP designers and developers • Strong portfolio demonstrating a deep understanding of brand identity.

2019-04-22T22:51:31Z

https://aquent.com/our-expertise/job-description-library/Sr-Brand-Designer-100791

aquent.com

clickid & sub affiliate id don't work over 00 characters in length. clickid & sub affiliate id limited to letters, numbers, underscore and hyphens. No space was permitted in the clickid & sub affiliate id. The variables tid0&sub_id must be lowercase.

2019-04-26T06:33:44Z

http://blog.geekbuying.com/2018/09/deeplink-generator/

blog.geekbuying.com

To put it into perspective, an indoor heated swimming pool will likely be somewhere in the region of 00-00°C and will start to feel pretty chilly at 00°C. British Triathlon insist that wetsuits are mandatory for competition in water below 00°C and it is unsafe to swim in anything below 00°C. Fresh water pools and open water will range from between 0-00°C throughout the year with people swimming in them all year round even at the lowest temperatures. But why? It has been found that the stress caused by the shock of cold water to the body, actually activates the immune system which we all know is key to fighting off those germs and infections and staying healthier for longer. To receive the real benefits of a boosted immune system experts say it is necessary to be exposed to cold water on a regular basis (0-0 times per week) as opposed to just once or twice a year. Your body will work twice as hard in cold water compared with regular swimming as it is fighting so hard to keep you warm. It is not going to build muscle or help you to perfect the perfect hand entry, however it will help you shed any excess pounds and probably help you to appreciate a regulated swimming pool that much more! This study suggests that swimming in cold water can reduce swelling and help with inflammation therefore aiding recovery and preventing delayed onset of muscle soreness (DOMs). Furthermore it is also known to improve your body's circulation as the heart tries to pump more blood to your organs. If like me, you think it's exciting to try new things and to challenge yourself then why not give it a go. Cold water swimming is not just for triathletes or super sporty people, anyone can do it! But one word of warning, your friends and family may well think you are mad. If you do decide to try swimming in cold water for the first time, please do so in a sensible and safe environment. Check out these tips from South London Swimming Club on staying safe in the water - click here. 000 yards (00.00m) - Largest lido in the UK! The Ladies' and Men's Ponds are the UK's only lifeguarded open water swimming facilities open to the public every day of the year. The mixed pool will open to public in the summer. The Total Motion Aquathlon is back for 0000 at Tooting Bec Lido, consisting of an 000m swim followed by a 0.0km run. Secure your place on the start line - register now.

2019-04-23T11:02:43Z

https://totalmotionevents.co.uk/news-blogs/the-benefits-of-swimming-in-cold-water/

totalmotionevents.co.uk

Join Tim and Carlos for an interview with a very special guest, Thomas W. Juodaitis, President of The Trinity Foundation! They discuss the history of The Trinity Foundation; the relationship between Gordon Clark and John Robbins; misrepresentations of Robbins' character and his work, as well as his criticisms of John Piper. They wrap up with an announcement of the 0000 Conference sponsored by The Trinity Foundation, "The Reformation at 000: Is It Over Or Is It Needed Now More Than Ever?" on October 00, 0000. Plenty of space is still available, so register soon! Register today! The Trinity Foundation is one of the best sources for Reformed theology, philosophy, apologetics, sound doctrine, and developing a Christian worldview of everything from science to politics. They also expose irrationalism and false teachings in "Christian" churches, seminaries and colleges. SRR #00 | Interview with Timothy Kauffman Regarding Tim Keller, Hermeneutics, and More!

2019-04-18T18:59:15Z

https://biblethumpingwingnut.com/2017/10/05/srr-62-interview-tom-juodaitis-trinity-foundation/

biblethumpingwingnut.com

These are really nice, even better than I thought from the picture. Love them! Top Goods. Like it very much. Thank You. Shipping very fast, perfect like the picture! Thanks.

2019-04-19T16:32:33Z

https://bellsbowsandwhistles.com/martejoven-3-pairs-set-gold-tone-lion-head-zebra-pattern-leopard-round-drop-earrings-set-for-women-fashion-accessories-gifts/

bellsbowsandwhistles.com

SKU: FUDPERF Categories: Fins, Fins Unlimited Longboard Fins, Fins Unlimited Longboard Fins 0' - 0', Longboard Fins 0"-0", Longboard Fins 0"-00" Available in 0″, 0″, 0″, 0″ or 00″ Fiberglass fins available in many colors. This is one of the basic High Performance fins in the Fins Unlimited. Works great as a Single or 0+0.

2019-04-20T21:20:49Z

https://easternlines.com/product/fins-unlimited-d-performance-fins/

easternlines.com

This supplement is simply the leaf of the olive plant, Olea europaea. It is the same tree that produces the olive fruit and olive oil that we all know. Pyrroloquinoline quinone, commonly known as PQQ or Methoxatin, is a powerful coenzyme that displays a wide range of antioxidizing, neuroprotective, and anti-aging properties. Acai berries are dark purple, almost black, colored fruits that grow on a palm tree native to Central America and the northern half of South America. Astaxanthin has gained widespread popularity in the United States as a dietary supplement recently because it functions as a potent antioxidant. One study concluded it offers 0,000 times the antioxidant effects of Vitamin C. Grapefruit is a citrus fruit grown in warm, subtropical climates around the world. It is known as one of the healthiest foods in the world. Many of us take supplements every day to boost our energy, make us healthier, or to get the crucial nourishment we need that we may not be getting in our diet. One common addition to many people's supplement regimen is alfalfa. Pomegranates are one of the world's finest super foods that can be used to maintain optimal health. In fact, it has been used as medicine for thousands of years and has been studied by scientists and researchers around the world. The reishi mushroom is a shelf mushroom that grows in many parts of the world. It is an important part of chinese medicine, and many chinese medicine practitioners refer to it as the "king of herbs". Oregano is a perennial, flowering herb in the mint family that grows wild and is cultivated throughout most of the word. The fresh and dried leaves are used in culinary preparations in many cultures. Oregano is a staple in the Mediterranean diet. Spirulina is a popular superfood and supplement. It is a blue-green alga similar to chlorella. Spirulina is often added to smoothies, energy bars or taken in tablet form. Although agmatine was discovered in the early 0000's, it is still not a well known substance yet. The reason for this is that most of the studies pertaining to it have only been done on animals. But very little of the research has been tried out on a group of humans. CoQ00, ConezymeQ00, is an antioxidant that is synthesized naturally in the body. Ubiquinol is the active antioxidant form of CoQ00 while Ubiquinone is the oxidized form. CoQ00 plays a significant role in different body chemical processes. As is typical of coenzymes, it helps the cells in food digestion, thus making it easier to synthesize energy.

2019-04-25T22:44:09Z

https://supplementhound.com/antioxidants/

supplementhound.com

Provides general background knowledge about the film industry, including technical information about lighting, script analysis, continuity and makeup application. Students are introduced to the roles and responsibilities of a Film/TV Makeup Artist. Students will learn which makeup products are best suited for different filming formats. Requirement: A non-refundable Makeup Kit must be purchased at the VCC bookstore prior to the first day of class. Please contact the downtown campus bookstore.

2019-04-24T04:21:27Z

https://www.vcc.ca/programscourses/courses/makeup-for-film-and-television-mkup-1107/

www.vcc.ca

In response to Chris Wetterich's March 00 story, "Vast majority of FOIA requests coming from the public," the Illinois Freedom of Information Act is an extremely important tool for the people in Illinois who participate in our democracy through monitoring the activities of their local governments, an indispensable check on our government officials. The attorney general's statistics reflecting the public access counselor's caseload mirror the Citizen Advocacy Center's experience with assisting members of the public who request records in order to inform themselves of community affairs that affect them, their families and their neighbors. We routinely assist people who are denied records, where the public body fails to satisfactorily explain why the exception taken applies to the requested records, and which ultimately result in a letter from the public access counselor's office stating that the requested records should be made public. Members of the public should be wary of legislative efforts to roll back the FOIA reform enacted in 0000. Since the bill's passage in 0000, each legislative session has seen several backlash bills aimed at curbing the people's access to documents that should be made public, and which are routinely made public in states that have stronger FOIA laws. It's everybody's job to stay vigilant so that our FOIA statute remains one of the strongest in the nation. In Jim Slusher's "Voting is ‘Plan Only,' and we have duty to help," he quotes a reader who says the "solution (to problems in local government) is greater citizen involvement to enhance public accountability." Slusher and the reader draw the legitimate conclusion that our eligible voting population is not using its power to hold local officials accountable. While voters surely hold this power, there are more direct mechanisms to holding local officials accountable while they conduct our governments' business, and that is through monitoring local government activities. Of course, if people perceive they lack time, or treat their civic duty as a low priority, they will not utilize this method. In fact, according to the 0000 Illinois Civic Health Index, less than 00 percent of state residents had attended a public meeting of one of their local governments in the preceding year. The problem is straightforward, and it's dire: Illinois fails to educate its youth in civics. Without a civically educated public, fewer involve themselves in using the political process to help prioritize and solve the problems they've identified as pressing concerns in their communities. The ultimate result is a crisis of legitimacy. People don't believe that the political system represents their interests, and yet they lack the confidence and skills to exercise their crucial role as responsible, civic-minded individuals to shape the political system to reflect a government we want, rather than one imposed upon us. How can we increase civic participation, whether through voting or through monitoring, in Illinois? We all need to clamor for legislative and financial support for stronger civic education curriculums at all our public schools so our state's future residents will be poised to help solve the pressing problems our state faces.

2019-04-22T00:18:43Z

https://www.citizenadvocacycenter.org/cac-blog/archives/03-2012

www.citizenadvocacycenter.org

TThe Instructable "Build A Child's Workbench Any Size You Want" shows how to build a child's workbench but not how to construct the bench top. This is the second in a series of Instructables on building inexpensive stout bench tops. All will be suitable for a parent and child to build together even if they have little or no woodworking experience. This bench top was made from a short piece of a glulam beam. Glulan is short for glue laminated timber and is used to carry loads in the houses and other wooden structures. TThe stub you find will be cut on one side and on the other is left as it came from the supplier. You need to decide if it needs to be trimmed. Shown are to pieces I snagged from a construction site dumpster. The one of the left has an end that does not look all that bad. (It has the industrial re-purposed look to it.) It is 0" thick, 00-0/0" wide, 00-0/0" long, and in my opinion is the perfect size for a bench top. If you are lucky enough to fine such a piece just clean it up with a wire brush, sand the edges, and skip the rest of this discussion. The one on the right will have to be cut. This will require the use of a hand saw. First don't panic! Using a hand saw to cut a beam is straightforward if you follow directions and find the right saw. Maybe you have an old hand saw that belonged to Grandpa or a Great Grand Uncle, or you found for $0 at some flea market. DON"T USE IT! I'll explain why. Old hand saws were great tools that, if taken care of, do an excellent job. That meant they were used by someone that knew how to take care of it and how to sharpen it. Between that person and you it has been abused and is now dull. A dull saw will ruin the experience and turn you off to hand tools. What you need is a cheap high quality thrown away panel saw. A panel saw is the type of saw you picture an old carpenters using. The theory of American saw makers was the make the saw from steel that was hard enough for the teeth to hold an edge, but soft enough to sharpen. It was assumed that the user would sharpen the saw. (This would be done before every major job.) Some people would send their saws out to be sharpened. This caused the saw to be sharpen less often and be dull more of the time. The Japanese saw makers took a different approach. They made saws from extremely hard steel that made the teeth difficult to sharpen. The idea was when the blade got dull, just replace it. The European and American saw markers have come around to this idea and now make saws that with induction hardened teeth. The result is a saw that is easy to use for the beginner and sharp for a long long time. Here are two saws I recommend. This is one of the easiest saws I have ever used and has become the first saw I reach for. It has 0 tpi and is a good general purpose (jack) saw. It is a best seller in England but is hard to find in the United States. They can be found on Ebay for less than $00 (including shipping). My only regret with this saw is that I didn't buy it years earlier. It has a 00" blade which is manageable for a child to use. If a could only have one saw, this would be it. This would be my second choice. At less than $00 it will do a good job. It has a 00" blade which makes it easy for a child to handle. With 0 tpi is doesn't cut as fast. It should be available locally. Use a square to mark cut lines on both the width and thickness of the beam. In this case the bench top will be 0" thick. 00-0/0" wide and 00" long. (Again this is also the ideal dimension of a bench top.) Take a knife and score the lines. It is better to score lightly several times than to score once really deep. Then make a beveled cut, on the waster side, to form a notch. This gives the saw blade a grove to follow. A big part of sawing is to hold it correctly. Grab the handle but leave your index finger out. It will point where you want to cut. Loosely hold the handle a make long easy stokes. (If your knuckles or fingers turn white that you are holding it too hard.) Let the teeth do the work. If the saw binds it is because you are bending a blade a bit. The saw cuts on the push so go easy on the way back. You will get better with practice. First check to see that there are not staples and nails in the cutting path. These very hard teeth do not handle metal very well. Place the beam on a short bench. Place the saw blade in the grove at the far corner of the beam and pull the blade back three time the set the cut. Then start cutting, making sure to stay on both lines. If you find you are getting off the line just nudge the saw back in place. Long easily strikes. This beam took about 00 minutes for me to cut. Hold the waste side to make sure it doesn't break off as you finish your cut. Note: Once you get experienced with a hand saw you will find you can go faster than someone with a power saw. I was helping a friend install a deck. While my friend went to get his saw and extension cord I already had half the cuts made. I also didn't have to worry about managing an extension cord so I moved from joist to joist lickity split. Clean up the edges with a bit a sand paper. You are now done. From direcctinss on buling the bench go to the Instructable " Build A Child's Workbench Any Size You Want". Enjoy your new saw and bench. Remember, you are really making memories.

2019-04-22T14:43:04Z

https://www.instructables.com/id/Childs-Workbench-Bench-Top-2-Glulam-Beam/

www.instructables.com

Places to go, places to love. How to create irresistible environments. Today's pick of the day. - Are you living your "Life on Purpose?" Places to go, places to love. How to create irresistible environments. Today's pick of the day. For years our family attended a large church in Atlanta where the consistent theme was creating irresistible environments. It's the same concept in the movie where Kevin Costner coined the phrase "If we build it they will come." His character in the movie Field of Dreams knew if he turned an unattractive field into a baseball diamond, many would come. Why? Because it would be irresistible. Today I joined a friend for a round robin at a tennis club. My assumption was a bunch of women playing one another. Yet when I arrived, I was informed that on my court was another lady and two pros. Men pros. Competitive men pros. Tennis is their profession. Quickly we realize the pros don't want to get beat by each other, so the other lady and I joined the war. While I'm competitive, I'll admit to being intimidated. A few minutes into play, one of the pros said, "Oh! Be right back!" He owns the club so we assume he must have quick business to attend. Yet a few seconds later, I heard music. Good music. Oldies, Tom Petty, Eagles, and the like. Next thing you know, we're singing along to Hotel California. For a moment, my tennis racquet became an air guitar. Soon I'd relaxed and loosened up. And yes, we won. Was it the music? Not necessarily. But it was an intentional shift in environment. People are drawn to environments where there is warmth, encouragement, and an air the breeds relationship. Environments like that don't just happen, they are created. Once I taught a seminar for a company that was kicking off a huge promotion. As I approached their floor from the elevator in the building, I could hear "We will rock you" playing where I was about to speak. My work was done before I arrived. I stepped right into an environment that had been carefully crafted to spur creativity and healthy competition. They were working together as a team, and having fun while doing it. Places. We gravitate to those we find irresistible. Comfortable, predictable, inviting, often even competitive. Small shifts can be the difference at home and work that make others want to stay and linger. Places to go, places to love. Create irresistible environments. They will come and they will long to stay. Today's pick of the day. Previous postPride vs. Humility: When the student is ready, the teacher appears. Today's pick of the day. Next postPeople Power. It's all about who you know. Better yet, who you NO. Today's pick of the day.

2019-04-25T21:52:19Z

https://bethtownsend.com/2014/08/28/places-to-go-places-to-love-how-to-create-irresistible-environments-todays-pick-of-the-day/

bethtownsend.com

Last edited by Oceania on Tue Aug 00, 0000 00:00 pm, edited 0 time in total. Sweet looking board mate. With all that advertising on the bottom, the YouTube clip and this post I hope Grant gives you a discount on your next board! Looks like a cracker board. Looking forward to a ride report in a few months. That's the shortest subX I've heard of. Personally,at that length, I hope you don't regret not getting the quad find option. Yeah its definitely sweet. I've got a 0"00 f skate quad. I think this will glide nicely with the large single. Grant says he has one the same size, his favourite board! Is yours the 0'00 with the orange rails and the retro miller paint job that was posted a few years ago with the TC Aqua line quad fins? They're an interesting board, ugly as hell but gaining quite a following. I noticed a guy called Mark Ogram in WA makes a range of boards very similar to Grant's range. There is an uncanny resemblance between Grant's SUB-X and Mark's "Kelvinator" Two guys of similar age on opposite sides of the country with very similar board design philosophies. Don't know if the bottom contours on the two boards are similar. I remember talking to Grant about the SUB-X, he said the bottom was quite complicated and a pain in the arse to shape. I've got a couple of Millers, and I'm heading down to Dunsborough tomorrow to pick up a 0nd hand Ogram "Wahoo" Yeah that's me with the Retro f Skate ☺. I thought I would go the other way with the SUB X, as it looks sort of old school and most the sprays I had seen where that way inclined. So I thought I would do my best to make this one look a bit more 'post modern'. It's just aesthetics really as the board will obviously perform the same no matter what colour and stickers. MULLET, your right in that is does look similar to the Ogram Kelvinator. I did look at that board as an option but am a Miller convert for sure. The buttom contours on the board are indeed complex and its obvious there is a lot going on in very subtle ways, all working together. Ill never forget seeing this picture the first time. All I could think was..... Perfect quad fish. Let me know if you ever decide to sell it.

2019-04-19T00:20:17Z

http://forum.realsurf.com/forum/viewtopic.php?f=9&t=30656

forum.realsurf.com

I am trying to understand what ElasticSearch exactly does when it comes to persistence. When I index documents in ElasticSearch, I also within this step save them within ElasticSearch. Though the reason I index my documents with ElasticSearch is to be able to search for them using the API and certain search algorithms. Then, within for the rest of my application, I also have a relational database where I store a lot of stuff concerning my application. Within the relational database I also have the same documents I index in ElasticSearch. As a result I have the documents saved in both ElasticSearch and the relational database. I learend about ElasticSearch to get extended search abilities, but now I wonder whether the step of saving the documents in ElasticSearch and the relational database isn't a bit redundant. Would it be wise to delete the documents from the relational database and use the indexed documents in ElasticSearch as the data source? Maybe. This is a design decision that our friends over at DBA Stack Exchange may have more to say about. Sometimes you make redundant copies because of different search or reporting needs, or database engines with different characteristics. A practical example, I know of an enterprise with a sprawling MediaWiki who built a search engine in Elasticsearch. The wiki and other sources have their own DBMSes supporting lots of CRUD applications. Then tens of millions of documents of all kinds are stuffed into the search engine, so people can usually find things. Not the answer you're looking for? Browse other questions tagged database elasticsearch or ask your own question. PHP - does curl run asynchroniously on my system? indexing a ~0gb database into elasticsearch: how?

2019-04-21T18:45:00Z

https://serverfault.com/questions/912799/elasticsearch-including-or-vs-database

serverfault.com

SKU: jbk-sku000 Categories: Contemporary, Doors, Fire Door FD00, Internal Doors Norwich, White Primed Doors Brand: JB Kind. A stylish collection of innovatively designed white internal doors which love being in the Limelight, old name!. With nine new additions in 0000, this popular range offers a combination of contemporary style and urban chic. Door faces are made of MDF with feature grooves- coated with an excellent white primer to take top coat finish. The range is also FSC® chain of custody certified and FD00 fire doors are available.

2019-04-21T10:09:00Z

https://www.thedoorandfloorshop.co.uk/product/jb-kind-white-contemporary-aster/

www.thedoorandfloorshop.co.uk

Dog cherry eye is a common eye issue in canines. It causes a red blob on the lower eyelid due to inflammation of tear producing gland. Cherry eye is most common in certain dog breeds including Cocker Spaniels, Bulldogs, Pekingese, Lhasa Apsos, Beagles and Boston Terriers. In this guide, I will be talking about cherry eye treatment options, surgery, reasons why cherry eye comes and goes and also home remedies that pet parents can use to keep their baby comfortable. What is dog cherry eye? "I see a red thing on my dog's eyelid". The ‘red thing' is the inflammation of the tear producing gland usually located on the lower eyelid. If you are wondering whether cherry eye is painful, the answer, thankfully, is it is not. It definitely looks scary and serious but your dog will not be in pain or too much discomfort. Many pet parents report that cherry red swelling comes and goes away every now and then. This is also normal. The swelling subsides and goes away in a couple of days but it recurs within a short period of time. Unlike humans, dogs have three eyelids and the reason why cherry eye occurs is because the tear gland is not well anchored to the lower eyelid. In some serious cases, the tear gland remains out permanently in which case, surgery is the only viable option to treat the condition. The fibrous attachment to the undersurface of the third eyelid becomes weak. This results in prolapsed or bulge of the tear producing gland resulting in cherry-like growth that is really the normal-size tear gland. Most common symptom is red cherry-like growth or bulge on the lower eyelid in the corner of the eye. It usually occurs for the first time in dogs below 0 years of age. Dogs prone to cherry eye also suffer from conjunctivitis frequently. This is characterized by watery or pus-like discharge. Dogs with cherry eye are also more likely to develop dry eye. Dry eye is also known as keratoconjunctivitis sicca. Many doctors prescribe antibiotics for cherry eye which make the swelling go down temporarily. However, despite antibiotics, the nictitating membrane gland often remains dislodged. So antibiotics may not be a permanent solution. Ophthalmic antibiotics help ease chronic inflammation. Sulfonamide antibiotics can ease dry eye. Cyclosporine and combination of artificial tears can help in some cases. In some dogs, a combination of corticosteroids and antibiotics can also ease the symptoms temporarily. Is cherry eye painful? Why does it come and go? As stated above, cherry eye will not hurt your dog but s/he may show signs of discomfort like excess blinking, or keeping the eye closed or even discomfort caused due to pus-like or watery discharge. The reason why the condition comes and goes is due to permanent prolapsed of the tear gland which can only be corrected surgically. Cherry eye can sometimes obstruct your dog's vision. In most cases, antibiotics and corticosteroids can help. Sometimes, the swelling goes down on its own. However, you need to keep an eye out to see if the condition recurs. In case it does, and typically, it will, your dog will need corrective surgery. This is especially the case when the tear gland remains out permanently. This type of eye surgery requires tacking the gland into position. Many veterinarians perform the procedure but it is best to seek out the services of an experienced veterinarian ophthalmologist. You may even want to develop a rapport with this expert since dogs with propensity to cherry eye are also more likely to develop other eye issues in the future. Note that the surgery is not a guarantee that the cherry eye won't recur. In the past, cherry eye surgery consisted or removal of the entire tear gland. This needed a lifetime use of eye drops since the pet could not produce tears. Today, vets know the importance of the tear gland and prefer repositioning or tacking the gland back into position. This is the main reason why there is no guarantee that the condition will not recur despite surgery. Having said that, there is a 00% success rate in most cases. Dog cherry eye surgery can cost anywhere between $000 and $0000 depending on the area you live in and the experience of the vet performing the procedure. Discuss all your options thoroughly with the expert and decide what is best for your pet. Some pet insurance companies cover the cost of this procedure. Recovery from the surgery should not take more than 0-0 days. Your vet might instruct using a collar to prevent your pet from scratching its eye. You also need to apply the ointment or eye drops as needed to heal the inflamed tissues. As can be seen there is not much you can do in case your pet develops cherry eye other than take him/her to the vet. You can manage symptoms of the condition by using prescribed ointments and cherry eye treatment antibiotics. Use a warm compress or saline rinse to handle the discharge. Avoid taking your pet to dusty areas where the condition can worsen. Use a pet collar to prevent your dog from scratching the eyes. Many pet parents are intimidated at the thought of putting eye drops or administering eye ointment in their pet's eyes. However, with a little practice, you can become a pro at this. An assistant will need to hold the dog if s/he squirms too much. If you have a high grooming table, place your pet on it. This is naturally only applicable to medium or small dog breeds. Apply the eye wash or saline rinse on a cotton wool. Firmly but gently clean the pet's eyes to remove discharge, if any. Use separate cotton balls for each eye. This is necessary to prevent the spread of germs from one eye to another. Next comes the medicine. An important thing to remember is to never touch the bottle/dropper or tip of the ointment tube to anything including your pet's eyes, your fingers etc. This is necessary to prevent contamination. Try a practice squeeze of the tube or bottle before you begin. Hold the bottle of drops in your hand. Keep your dog in front of you but facing away from you. Use your other hand to tip his face (nose) upwards so that his eye is at a horizontal level. Hold the bottle 0 inches above your pet's eyes. Firmly squeeze the bottle. Your pet might try squeezing its eyes shut, in which case, you need to gently but firmly open its eyelid with the thumb of your other hand. In case you are using an ointment, tip your dog's face upwards, lift the upper eyelid and apply the ointment on the white areas of your dog's eyes. Cherry eye is an uncomfortable condition that impacts certain dog breeds. In most cases, surgery is the only treatment option and it involves repositioning the third eyelid and tear gland. We hope this brief guide helps you. What Dog Harness and Liner is Best for Your Dog and Yourself?

2019-04-19T14:29:55Z

https://www.dogideas.net/dog-cherry-eye-treatment-options/

www.dogideas.net

The slim powerbanks S0000 and S00000 are true performance packages in an attractive, ultra-slim design. With capacities of 0000 and 00000 mAh they are perfect for mobile devices like smartphones, tablets, navigation devices, mp0 players or digital cameras that are recharged with a current output up to 0.0 Ampere in an instant. Thanks to the integrated microUSB cable, Android smartphones and tablets can be directly connected with the powerbanks. Moreover, other charging cables can be connected to the usb port, in order to recharge any kind of mobile devices.

2019-04-18T10:28:31Z

https://m2m-direct.co.uk/index.php?option=com_virtuemart&view=productdetails&virtuemart_product_id=2632&virtuemart_category_id=974&Itemid=553

m2m-direct.co.uk

I definitely appreciate a good local wine. We BC residents are so lucky to have some incredible wineries right here in our own backyard. Here are eight of my top picks you can try out focusing on regions - off the coast, near the city, by the lake, and from your tent. This winery's backstory is summed up in one perfect phrase: "from corporate suits to gumboots". The owner put his passion for wine ahead of the daily grind and pursued his dream of having a French Chateau or Tuscan Villa of his own on Vancouver Island. Their wines are unique because of the cold climate of the region and the whites have a wonderful acidity, while reds are nice and bright with a light to medium body. Built on a passion for wine and food, Unsworth is the result of one family bringing their dream to fruition one vine, bottle and blend at a time. The results of their care and efforts are palpable when you visit this beautiful winery. Guests can sample their wide array of wines ranging from ethereal sparkling wines to their bold red Meritage blend. By using excellent grapes sourced from the Oliver-Osoyoos area and old fashioned wine-making techniques without chemicals or mechanical pumps; there is an uncompromised quality in Blackwood Lane wines. This boutique winery in the heart of the Fraser Valley wine corridor is only minutes from Vancouver. Established in 0000, Township 0's main focus is making quality wine and nothing else. Everyone from first time visitors to major oenophiles will enjoy the wine, art, culture and culinary experiences brought together by the knowledgeable staff here. Their Chardonnay was even served to the Queen at the Government of Canada State Dinner in 0000. For the last 00 years, Sumac Ridge Estate Winery has been producing quality BC VQA wines and was BC's first operating estate winery. Since the 0000s, the area's combination of sparkling water, brilliant sun and fertile land has made it ideal for growing grapes. And the grapes grown at Sumac Ridge produce incredible Gewürztraminer, Merlot, Sauvignon Blanc and Chardonnay. Since it's opening in 0000, this whimsical winery offers guests a different experience than most other places. Visitors tend to stay longer than at other tastings. It is, after all, the "Home of The WOOPSICLE", a delicious, vibrantly colored, wine-based popsicle. Guests can sample wines at their eight different sampling stations and enjoy live music out in the garden. Clos du Soleil is a small artisan-style winery and estate vineyard that focuses on producing premium quality wines. Their aesthetic is borrowed from the great wines of Bordeaux, but stamped with the flavors and aromas of the rocky Similkameen terroir. This organic estate vineyard creates a broad spectrum of wines like their expressive Gewurztraminer, easy going, off dry rosé, Flamingo, to the complex, Meritage. Best known for their signature wine, the Gamay, Robin Ridge strives to give you a taste of the Similkameen in every glass. This award-winning boutique winery focuses bottling its wine in small lots and the care put into each reserve is palatable. Its grapes are grown on the Erickson Bench which gives their wines a unique Kootenay fingerprint. Their current selection features everything from a fruity, 0000 Récolte Blanche to a rich, 0000 Pinot Noir Reserve. This rustic-style winery has an unmistakably homey feel. Guests will feel relaxation and comfort when visiting "the Burl", the log cabin style tasting room and gift shop. Their wide selection of wines pay tribute to the stunning backdrop of the Kootenays. No matter what your wine preferences are, we have incredible wineries, right here in BC, that can serve just what you are craving. I encourage you to get out, explore and support our local wine businesses. You will be amazed at what you will discover. Happy travels!

2019-04-25T08:58:50Z

https://winebc.com/taste_terroir/where-to-go-wine-touring-in-bc/

winebc.com

Basically, anyone who is interested in building with wood can learn it successfully with the help of free woodworking plans which are found on the net. The specific way each feature is presented and the material covered in these sites are the best reason for downloading 0x0 Redwood Deck Plans woodworking plans for your construction projects. Even though the plans provided in them are more suited to the needs of professional and advanced woodworkers, the suggestions and guidance offered can even make the most ignorant person successfully complete any 0x0 Redwood Deck Plans woodwork projects. Professionals find the free plans useful because it helps them save time in creating designs for their clients. With the 0x0 Redwood Deck Plans free woodworking plans package, you will get help to build all kinds of projects, be it furniture, sheds, beds or wind generators. These plans are very user friendly which helps in making each woodworking project enjoyable and simple. These online plans offer more options to woodworkers than any other sources. You can find the perfect woodworking plan according to your level of expertise or desired need. There are plans for beginners, professional and weekend hobbyists. For newcomers, these plans are a must have package as they are very simple to use and contain colored images of the highest quality and detailed instructions stepwise for every woodworking projects. Many of these 0x0 Redwood Deck Plans free woodworking plans online allow you to access thousands of ideas to assist you in building your project in a quick and professional way. You get blue prints, images and materials when you download these plans from the net. It does not matter whether you are skilled or not, these detailed instructions will assist you all through your project till you have completed it successfully. You will also get tips on how to start a woodwork business from some of the free woodwork plans online. These 0x0 Redwood Deck Plans woodworking plans also have few limitations to speak of, though these are minor ones compared to the advantages you gain from them. One of the common complaints about free plan software is the time which is taken for it to get downloaded completely. These plans are quite vast and if the internet is slow, it might take you hours to download the whole 0x0 Redwood Deck Plans plan. The other disadvantage of free plan is that the measurement provided is of a specific kind even though both kinds of measurement systems are available. You lose time by making the effort to convert the measurements into your kind of measurement system. On the whole, any of the free plan software are great and every woodworker can greatly benefit from the plan packages for building woodworking projects in a confident and successful way. The free woodworking plans are worthy of a trial. This is true, especially, when you need assistance in your woodworking skill, while working on a specific project. You can select from the vast amount of plans available in the free 0x0 Redwood Deck Plans woodworking plans online, which are offered by expert and experienced woodworkers. If you are beginner and very interested in doing a DIY project for home then, 0x0 Redwood Deck Plans can be interesting. If you do not have the proper information, instruction, and skill, you may land up spending more money and time than you originally intended to spend. As a beginner woodworker, you need have the space, time and the correct tools. Having said, there are a few essential factors that you should keep in mind, before starting with any woodworking project. If you keep these essential points in mind before you begin a 0x0 Redwood Deck Plans woodworking project, it will become very easy for you to achieve success. Woodwork requires planning as much as it requires effort. So how do you get started?

2019-04-25T04:31:11Z

https://mechka-smolyan.com/free-diy-plans/2x6-redwood-deck-plans

mechka-smolyan.com

It&apos;s nearly 00 years since the Toys R Us building was built at Western Approach, and time has not been kind to the old girl. Now an unloved eyesore the building has been given another blow after Toys R Us announced the Plymouth &apos;warehouse store&apos; will close following a period of poor sales and an attempt by the company to cut costs. The building has slowly lost the love of the city, its shoppers and the council, it seems, with the dirty and generally unpleasant feel of the area left to its own devices. Walkways and lifts have been closed down and anti-social behaviour has plagued the site since it was built in the late 0000s. So what does the future hold for one of Plymouth&apos;s most recognised buildings? Plymouth City Council have already said the building and car park are not earmarked for demolition. The car park, which is still used regularly, is one of the few other reasons to head to the site. With two hours&apos; free parking it provides a welcome break from the pay and display areas of the city centre, and encourages shoppers to visit the store. When The Herald reported on the sad news the store was likely to close in early 0000, there was a mixture of responses on social media. With dozens of comments left on our Facebook post, it seems many in the city have an opinion on the store, the sad news for staff and what should happen to the site. Some on Facebook have blamed the store&apos;s demise on its high prices, the rise of cheaper online shopping, the location, high business rates and even the poor staffing levels. Increased competition from Smyths Toys off Exeter Street and The Entertainer in Drake Circus mall are unlikely to have helped the store&apos;s profits. Despite the grim outlook for the store, many vented their sadness that the shop would close, and their childhood memories of buying toys at the store would be crushed. Commenting on the building, and what may happen to it, many in Plymouth seem to have their own ideas, with one person believing it should be protected, and even listed. Some feared the huge building could be converted into students flats, other believe the shop may join the growing list of Plymouth&apos;s empty buildings. Many have come to the conclusion its days are numbered, and it will eventually be knocked down and the site will form part of ambitious new plans for the West End of town and Millbay. What do you think should happen to the Toys R Us building, and the Western Approach car park? Let us know in the comments section below.

2019-04-18T16:31:23Z

https://www.plymouthherald.co.uk/whats-on/shopping/what-people-plymouth-think-happen-906451

www.plymouthherald.co.uk

Vision wallpaper collection was designed to reflect a harmonious balance with nature. Paying an artistic tribute to the world around us, these beautiful looks show inspiration from the earth, the sea, trees and sky. The wallpapers have an eco-chic allure, and exhibit sophisticated printing techniques. Expanded inks, subtle shadowing and chic distress effects exalt the designs to high fashion heights.

2019-04-22T19:04:10Z

https://www.brewsterwallcovering.com/vision-wallpaper-book

www.brewsterwallcovering.com

Britain is "first in line" for a trade deal with the US, Boris Johnson has said after talks with Donald Trump's senior advisers. The closeness of the relationship between the UK and US will not change once the president-elect takes office, the Foreign Secretary insisted. Why, it's almost as if Brexit liar Boris Johnson either hasn't a clue what he's talking about, or is, well, a liar. There's no "possibly" about it.

2019-04-20T10:46:05Z

http://gruts.com/first-in-line/

gruts.com

Find Your Home in The Greater Phoenix Area! The Daniel Montez Real Estate Group specializes in Phoenix real estate. We love Phoenix! And we're passionate about the real estate market here. © 0000 Arizona Regional Multiple Listing Service, Inc. All rights reserved. All information should be verified by the recipient and none is guaranteed as accurate by ARMLS. The ARMLS logo indicates a property listed by a real estate brokerage other than The Daniel Montez Real Estate Group. Data last updated 0000-00-00T00:00:00.00.

2019-04-25T16:17:58Z

https://www.valleyrealestatedeals.com/

www.valleyrealestatedeals.com

Arbor Networks, a leader in securing the world's most complex networks from DDoS attacks and advanced threats, is searching for the right person to help execute our global training & enablement strategy for our sales team and channel partner. The perfect candidate has a dynamic personality with excellent presentation skills and comes with knowledge of networksecurity. This position is based in Boston and reports into the Director of Sales and Channel Enablement.

2019-04-26T14:45:28Z

https://www.theladders.com/job/sales-channel-enablement-manager-netscout-ct_38809645

www.theladders.com

We give equal consideration to the full range of academic and vocational qualifications - if you're unsure don't hesitate to call the admissions tutors - the number is on the course page. You can gain considerable knowlege from work, volunteering and life. Under recognition of prior learning (RPL) you may be awarded credit for this which which can be credited towards the course you want to study.

2019-04-25T14:34:31Z

https://www.tees.ac.uk/sections/postgrad/pg_entryreq.cfm?cookies=true

www.tees.ac.uk

> please don't top post as it makes reading continuity difficult. When this email is not a top-post (is it?), my previous wasn't too.

2019-04-23T22:15:04Z

https://linuxtv.org/pipermail/linux-dvb/2007-November/022022.html

linuxtv.org

The sleek and thoroughly modern X Series guitars are built for speed, power and aggression. The extreme contours on the body and the neck joint provide comfort as well as a distinctively high-tech look. The super fast neck and large jumbo frets facilitate speed and precision in your playing - from over-the-top shred to pummeling metal rhythm.

2019-04-22T02:02:41Z

https://dialmusik.com/product/cort-x1-bks/

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Brazil's dengue vaccination program in Paraná marks the first of its kind in Latin America. The populous region has more than 00 million residents, 00% of whom live in densely-populated urban centers. Dengue incidence has tripled from 0000 to 0000, prompting Paraná health officials to lead the way in embracing the first dengue vaccine. Officials there say they initial campaign will target 000,000 people in urban areas where the human and economic burden of dengue fever is highest. People around Brazil can also access the dengue vaccine program at private healthcare clinics. During the period from 0000 to 0000, Paraná has recorded more than 00,000 cases of dengue, 000 cases of severe dengue, and 00 deaths, at a cost of around €00 million. The introduction of the immunization initiative makes Paraná the first state in the Americas to avail of the vaccine. The new vaccine fits into a broader dengue control strategy which includes robust disease monitoring and engagement with local communities, according to officials in Paraná. "The world finally has a clinical prevention tool against dengue that has been shown to be efficacious in the Brazilian population, as well as endorsed by the WHO," says, Michele Caputo Neto, Minister of Health for Paraná State. Dengue continues to represent a growing public health threat for Brazilians with disruptive outbreaks that often paralyze local healthcare systems. As the country prepares for visitors attending the Olympic opening ceremony in Rio next week, its health service will be in the spotlight will be hoping to avoid major epidemics. In 0000, over 0.0 million Brazilians reported being ill with dengue. The real figure may be much higher. Almost 00% of the reported dengue cases in the country occur in individuals 00 to 00 years of age0, which falls within the approved age range (0 to 00 years) for the Dengvaxia® vaccine in Brazil. This pre-adolescent to adult population represents a highly mobile and social segment of the community who contribute significantly to spread the infection. In 00 of Paraná's municipalities, people between 00 and 00 years will be vaccinated. In the municipalities of Paranaguá and Assaí the vaccine will target the complete age range - between 0 and 00 years. This approach has been taken because the younger population, between 00 and 00 years of age, account for about 00% of the dengue cases in Paraná. The full vaccine age range will be targeted in municipalities with a disease incidence greater than 0,000 cases per 000,000 inhabitants. Paraná's new dengue vaccination program is not the world's first - that honor was claimed by the Philippines earlier this year - but it does make the Brazilian state a trendsetter in the region. The vaccine is also registered in Mexico, El Salvador and Costa Rica. Regulatory review processes for the dengue vaccine are continuing in other countries where dengue is a public health priority. More good news may not be far away: Mexico's national advisory council on immunization has also agreed on recommendations for the use of the dengue vaccine, prompting speculation that it could become the next country to launch a public program. Will Paraná's public program put pressure on its peers?

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(00) The term "production" includes the manufacture, planting, cultivation, growing, or harvesting of a controlled substance. (C) the control of which is necessary to prevent, curtail, or limit the manufacture of such controlled substance. (00) The term "Secretary", unless the context otherwise indicates, means the Secretary of Health and Human Services. (C) protracted loss or impairment of the function of a bodily member, organ, or mental faculty. (00) The term "State" means a State of the United States, the District of Columbia, and any commonwealth, territory, or possession of the United States. (00) The term "ultimate user" means a person who has lawfully obtained, and who possesses, a controlled substance for his own use or for the use of a member of his household or for an animal owned by him or by a member of his household. (00) The term "United States", when used in a geographic sense, means all places and waters, continental or insular, subject to the jurisdiction of the United States. (00) The term "maintenance treatment" means the dispensing, for a period in excess of twenty-one days, of a narcotic drug in the treatment of an individual for dependence upon heroin or other morphine-like drugs. (00) The term "detoxification treatment" means the dispensing, for a period not in excess of one hundred and eighty days, of a narcotic drug in decreasing doses to an individual in order to alleviate adverse physiological or psychological effects incident to withdrawal from the continuous or sustained use of a narcotic drug and as a method of bringing the individual to a narcotic drug-free state within such period. (00) The term "Convention on Psychotropic Substances" means the Convention on Psychotropic Substances signed at Vienna, Austria, on February 00, 0000; and the term "Single Convention on Narcotic Drugs" means the Single Convention on Narcotic Drugs signed at New York, New York, on March 00, 0000. (B) The designation of gamma butyrolactone or any other chemical as a listed chemical pursuant to paragraph (00) or (00) does not preclude a finding pursuant to subparagraph (A) of this paragraph that the chemical is a controlled substance analogue. (00) The term "listed chemical" means any list I chemical or any list II chemical. (A) Anthranilic acid, its esters, and its salts. (C) Ephedrine, its salts, optical isomers, and salts of optical isomers. (D) Ergonovine and its salts. (E) Ergotamine and its salts. (F) N-Acetylanthranilic acid, its esters, and its salts. (G) Norpseudoephedrine, its salts, optical isomers, and salts of optical isomers. (H) Phenylacetic acid, its esters, and its salts. (I) Phenylpropanolamine, its salts, optical isomers, and salts of optical isomers. (J) Piperidine and its salts. (K) Pseudoephedrine, its salts, optical isomers, and salts of optical isomers. (Y) Any salt, optical isomer, or salt of an optical isomer of the chemicals listed in subparagraphs (M) through (U) of this paragraph. (E) Repealed. Pub. L. 000-000, title XXIII, § 0000(b), Nov. 00, 0000, 000 Stat. 0000. (G) 0-Butanone (or Methyl Ethyl Ketone). (00) The term "regular customer" means, with respect to a regulated person, a customer with whom the regulated person has an established business relationship that is reported to the Attorney General. (00) The term "regular importer" means, with respect to a listed chemical, a person that has an established record as an importer of that listed chemical that is reported to the Attorney General. (00) The term "regulated person" means a person who manufactures, distributes, imports, or exports a listed chemical, a tableting machine, or an encapsulating machine or who acts as a broker or trader for an international transaction involving a listed chemical, a tableting machine, or an encapsulating machine. (B) a distribution, importation, or exportation of a tableting machine or encapsulating machine. (00) The term "chemical mixture" means a combination of two or more chemical substances, at least one of which is not a list I chemical or a list II chemical, except that such term does not include any combination of a list I chemical or a list II chemical with another chemical that is present solely as an impurity. (lxxv) any salt, ester, or ether of a drug or substance described in this paragraph. (i) Except as provided in clause (ii), such term does not include an anabolic steroid which is expressly intended for administration through implants to cattle or other nonhuman species and which has been approved by the Secretary of Health and Human Services for such administration. (ii) If any person prescribes, dispenses, or distributes such steroid for human use, such person shall be considered to have prescribed, dispensed, or distributed an anabolic steroid within the meaning of subparagraph (A). (II) the drug or substance has been, or is intended to be, marketed or otherwise promoted in any manner suggesting that consuming it will promote muscle growth or any other pharmacological effect similar to that of testosterone. (III) is not anabolic or androgenic. (iii) In accordance with section 000(a) of this title, any person claiming the benefit of an exemption or exception under clause (ii) shall bear the burden of going forward with the evidence with respect to such exemption or exception. (00) The term "international transaction" means a transaction involving the shipment of a listed chemical across an international border (other than a United States border) in which a broker or trader located in the United States participates. (C) bringing together a buyer and seller, a buyer and transporter, or a seller and transporter. (00) The term "felony drug offense" means an offense that is punishable by imprisonment for more than one year under any law of the United States or of a State or foreign country that prohibits or restricts conduct relating to narcotic drugs, marihuana, anabolic steroids, or depressant or stimulant substances. (ii) may be marketed or distributed lawfully in the United States under the Federal, Food, Drug, and Cosmetic Act [00 U.S.C. 000 et seq.] as a nonprescription drug. (B) Such term does not include a product described in subparagraph (A) if the product contains a chemical specified in such subparagraph that the Attorney General has under section 000(a) of this title added to any of the schedules under section 000(c) of this title. In the absence of such scheduling by the Attorney General, a chemical specified in such subparagraph may not be considered to be a controlled substance. (00) The term "regulated seller" means a retail distributor (including a pharmacy or a mobile retail vendor), except that such term does not include an employee or agent of such distributor. (00) The term "mobile retail vendor" means a person or entity that makes sales at retail from a stand that is intended to be temporary, or is capable of being moved from one location to another, whether the stand is located within or on the premises of a fixed facility (such as a kiosk at a shopping center or an airport) or whether the stand is located on unimproved real estate (such as a lot or field leased for retail purposes). (00) The term "at retail", with respect to the sale or purchase of a scheduled listed chemical product, means a sale or purchase for personal use, respectively. (A) The term "retail distributor" means a grocery store, general merchandise store, drug store, or other entity or person whose activities as a distributor relating to ephedrine, pseudoephedrine, or phenylpropanolamine products are limited almost exclusively to sales for personal use, both in number of sales and volume of sales, either directly to walk-in customers or in face-to-face transactions by direct sales. (iii) A drug store is an entity within SIC code 0000. (00) The term "Internet" means collectively the myriad of computer and telecommunications facilities, including equipment and operating software, which comprise the interconnected worldwide network of networks that employ the Transmission Control Protocol/Internet Protocol, or any predecessor or successor protocol to such protocol, to communicate information of all kinds by wire or radio. (00) The term "deliver, distribute, or dispense by means of the Internet" refers, respectively, to any delivery, distribution, or dispensing of a controlled substance that is caused or facilitated by means of the Internet. (ix) any other persons for whom the Attorney General and the Secretary have jointly, by regulation, found it to be consistent with effective controls against diversion and otherwise consistent with the public health and safety to exempt from the definition of an "online pharmacy". (00) The term "homepage" means the opening or main page or screen of the website of an online pharmacy that is viewable on the Internet. (G) is being conducted under any other circumstances that the Attorney General and the Secretary have jointly, by regulation, determined to be consistent with effective controls against diversion and otherwise consistent with the public health and safety. (B) does not include the issuance of a new prescription to an individual for a controlled substance that individual was previously prescribed. (C) the practitioner, acting in the usual course of professional practice, determines there is a legitimate medical purpose for the issuance of the new prescription. (C) orders of controlled substances of unusual frequency. (B) the offender's release from any term of imprisonment was within 00 years of the commencement of the instant offense. (B) any offense that would be a felony violation of section 000 of title 00, if the offense were committed in the special maritime and territorial jurisdiction of the United States, for which the offender served a term of imprisonment of more than 00 months.

2019-04-20T20:46:59Z

https://casetext.com/statute/united-states-code/title-21-food-and-drugs/chapter-13-drug-abuse-prevention-and-control/subchapter-i-control-and-enforcement/part-a-introductory-provisions/802-definitions?ref=AsVVwS!LAn7z1

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Pip (Philip Pirip) - The novel's main character and narrator is raised by his ill-tempered sister. Pip never knew his parents and his first recollection of them occurs at the church graveyard, where he is threatened by an escaped convict. Pip is initially satisfied with his station in life and wishes to be apprenticed to Joe, his sister's husband, as a blacksmith. After meeting Estella at Miss Havisham's house, Pip becomes dissatisfied and decides that being a blacksmith is not good enough. Four years into his apprenticeship, Pip receives a large sum of money and the promise of a gentleman's education. Pip's good fortune transforms him into a snob. The narrator Pip is grown up and often reflects ashamedly on his past behavior. Joe Gargery - Pip's brother-in-law. Joe is a good and loyal friend to Pip and the only person who showed him love when Pip was a boy. Joe remained loyal despite Pip's snobbish behavior towards him. Mrs. Joe - Pip's sister who raised Pip "by hand." She is an unsympathetic character, who rules by force. She receives a crippling blow to the head shortly before Pip inherits his fortune, becomes a vegetable, and dies not long after. Miss. Havisham - Abandoned on her wedding day, Miss Havisham spends the rest of her life at Satis House, her dungeon-like home. She wears her wedding dress, has not seen the sun in years, and keeps the bride's cake, covered in cobwebs and gnawed by mice, on a table in her tomb-like room. She raises Estella for the sole purpose of getting revenge on the male species. She invites Pip to entertain her until he is apprenticed to Joe Gargery. Estella Havisham - Estella is beautiful, intelligent, and raised to torment men. She scorns Pip and treats him poorly on his visits to Satis House. Despite his ill treatment, Pip falls in love and dedicates his life to getting her approval. The Convict - The novel begins with a convict forcing Pip to bring him food and a file. Despite a rough exterior, the convict proves himself to be a generous man. Mr. Wopsle - A friend of the Gargerys, Wopsle serves as comic relief throughout the novel. He accompanies Joe and the soldiers as they track down Pip's convict and is harangued by Jaggers for passing judgment on an accused killer. He leaves his position in the church, heads to London, and wishes to become a great actor. Uncle Pumblechook - Pumblechook, Joe Gargery's uncle, is present at the Gargery Christmas dinner as the novel opens. He is pompous, arrogant, and mean to Pip. Once Pip gains his fortune, Pumblechook takes credit for it and treats him well. Orlick - Joe Gargery's journeyman blacksmith treats Pip meanly and dotes on Biddy. Biddy - Pip's first teacher, Biddy is common and has a good heart. She takes care of Mrs. Joe after the assault. Mr. Jaggers - Pip's guardian is one of the top lawyers in London. He also serves as Miss Havisham's lawyer. Wemmick - Wemmick lives two lives: he's Mr. Jagger's clerk at the office and a loyal son at his castle home. He invites Pip to dine with him shortly after his arrival in London. Miss Skiffins - Wemmick's beloved-her relationship with Wemmick contrasts the mostly negative relationships Pip witnesses. Bentley Drummle - Pip hates Drummle, a fellow student at the Pocket house, because he is a brute and because he maintains affection for Estella. Startop - Another fellow student, Startop befriends Pip and Herbert. Herbert Pocket - Originally the pale young gentleman who boxes Pip at Miss Havisham's, Herbert becomes Pip's closest friend in London. Herbert is kind, honest, and ambitious. He is corrupted by Pip's lavish spending and tries to keep up with him, a practice which leads him into debt. Matthew Pocket - Herbert's father refuses to compete for Miss Havisham's favor and makes a living tutoring young gentlemen, including Pip. Mrs. Pocket - Herbert's mother is obsessed with social status and laments that her grandfather should have been a baronet. She complains that marrying Matthew lowered her social status. Mrs. Pocket is an incompetent wife, mother, and homemaker. Sarah Pocket - Sarah hates Pip. She seeks Miss Havisham's favor in order to inherit her fortune. Camilla and Raymond - They too resent Pip. They flatter Miss Havisham, hoping to gain her favor and fortune. Clara - She lives with her father by the river and is loved by Herbert. Abel Magwitch - The first convict later makes his fortune in Australia. Compeyson - The second convict is the man who deserts Miss Havisham. The Man at the Three Jolly Bargemen - The third convict appears at the Three Jolly Bargemen, stirs his drink with a file, and hands Pip two one-pound notes. I trust you have great expectations for this study guide.

2019-04-25T01:58:21Z

https://www.brighthubeducation.com/homework-help-literature/34838-study-guide-great-expectations-characters/

www.brighthubeducation.com

Travel by bus from the central station: Busline 00 (ri. sloterdijk station): get out at busstop "Assendelftstraat" - Restaurant " REM eiland" You can contact Rob through the Contact Host button on this page. If you've already booked, go to My travels.

2019-04-25T01:54:56Z

https://www.misterbandb.com/rooms/8445

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My family and I took a short break to visit my son who works there a few days ago. It was lovely to see this busy city rain-washed and yet bustling. On seeing the Gate Way of India and the entire shoreline it reminded me of a washed canvas and hence I took to watercolor my image of Mumbai. It is also a nostalgic trip down memory lane for me to when I started painting using the medium of watercolor - in tones of sepia. I had my first solo exhibition of watercolors at a reputed bank in the year 0000.

2019-04-23T19:51:05Z

http://www.beenapradhan.com/blog/watercolor/

www.beenapradhan.com

Stay cool, comfortable, and stylish with this workout wardrobe staple. Our tank top frees you to focus on your efforts without restriction thanks to a cut that allows mobility. The lightweight design allows plenty of airflow, and the soft fabric feels good next to your skin.

2019-04-20T20:19:28Z

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We all breathe, but did you know that breathing is a great way to relax the body. If you want to learn how to breathe properly, watch a baby. While all of us know how to breathe in-and-out, pretty much most of us do not breathe correctly. Unlike a baby, we tend to breathe from our chests, not from our diaphragms. However a deep breathing is healthy and it can reduce your stress! It is hard to believe that probably one of the best stress management tools is right under our noses! When stress starts to build up in your body, you begin to start to take "shallow" chest breaths. As a result you are filling up only the top part of your lungs with air. So next time you are doing an exam, performing in front of a crowd, or stuck in commuter traffic - or indeed any time you feel tense, you are likely to breathe shallowly from the chest. So as your shallow breathing continues, oxygen levels drop and stress chemicals are secreted into the blood stream. A vicious cycle occurs, with these stress hormones triggering more shallow breathing and so you become more anxious. As less oxygen is circulated and your stress levels increase, you are less able to think clearly. You become tenser. These breathing exercises are designed to counter the stress response. By using diaphragmatic breathing, these breathing exercises will reduce your stress so that you can focus on what you have to do.

2019-04-24T13:51:16Z

http://www.stresshack.com/breathing.html

www.stresshack.com

I often wonder how people believe that restaurants, bars and nightclubs make money on food. CNBCPrime ran an edition in 0000 called "Hotel: Behind Closed Doors at Marriott," which revealed that Marriott doesn't make any money on food. In fact, Marriott doesn't even make money on rooms! Marriott makes nearly all of its money on liquor! Who would ever have thought that?! This CNBC edition is most informative. The clear message I heard is that restaurant, bar and nightclub owners need to thoroughly understand that there is a science to selling liquor. The clear message for restaurants, bars and nightclubs is that liquor can be immensely profitable, but maximizing liquor profits begins with design. Let's face it, when you pour drinks you have a production line. How do factories maximize their profitability? Factories dedicate a great deal of resources to maximizing the efficiency of their production lines. Why? To maximize profits. Manufacturing companies have been known to even change the color of their walls to boost worker morale, for the sake of greater productivity, because the people who own and manage these companies "get it." Think of your bar as a factory that produces drinks. Therefore, a bar needs to receive the same level of attention as any other factory. You might be making money by default, because selling liquor is so profitable that you can afford to make mistakes. Maximizing liquor profits in your restaurant, bar or nightclub begins with the design of the bar itself, including a thorough understanding of the equipment. Oh yeah, if you really want to make money with your bar, don't ask your architect! I break this down to two principles - 0). Exciting design and 0). Productive design. I don't mean to diminish the importance of operational expertise, but let's face it - if you don't have the first two elements, you won't have much to manage. Exciting design requires that you have to have something that drives people to your establishment and makes them want to stay. We design nightclubs and bars every day and understand that creative design absolutely drives people to your establishment. The ideal situation for creative bar design - configuration and placement - is achieved with a new club or a total remodel. But not all is lost if your bar doesn't fall into this category. Truly creative bar design can often be achieved in an existing club, which probably explains why I so love this type of challenge: building a better mousetrap! Our immensely popular LED bar, shown at the top of this story, is designed to be retrofitted for virtually any existing bar. · How far does the bartender have to reach to serve drinks? · How far does the bartender have to travel to make drinks? · Back bar bottle display, including placement, shelf heights, etc. · What is the depth of your aisle? · Do you have 0-compartment sinks? · Do you have a draft beer system, and if so, where is the tower located? · Where are your POS monitors located? · Where is your blender and what is its shelf height? · Do you use speed rails and how and where are they located? · Where is your dump sink located? The above is just a sampling of the issues we evaluate when designing bars. Obviously, if you are locked-in on your layout, there is only so much that can be done. We can help you greatly improve your efficiency even in an existing bar that cannot be moved, as the above information suggests. In other words, there are many ways we can help your bar and bartender efficiency. The images above, right, depict the plans and specifications included in our standard bar design service. If you would like to know more about equipment, please see our post "Top 0 Design Tips and Advice for Bar & Nightclub Owners," below.

2019-04-19T16:51:34Z

http://cabaretdesigners.com/design-buzz/entry/how-to-achieve-maximum-bar-profits-through-design

cabaretdesigners.com

Yes! Please sign me up to receive e-mails and other communications from Auto Haus VW. And please send me information on products, promotions and other related information. Auto Haus VW 00.0000000, -00.0000000.

2019-04-26T10:42:20Z

https://www.goautohausvw.ca/contact-parts/

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0. Enter your Registered Tatasky Number and Proceed. 0. Initiate your Recharge atleast Rs 000 or more. 0. Choose your Payment mode as "PayzApp wallet". 0. Pay the amount via PayzApp wallet, You will get the 00% cashback upto Rs 000 in your PayzApp wallet soon. 0. Minimum Recharge amount should be Rs 000. 0. Valid only when you pay via PayzApp at Tatasky.com or Tatasky Mobile App. 0. Maximum cashback is Rs 000.

2019-04-23T00:54:25Z

http://rechargetricks.in/tatasky-get-25-cashback-upto-rs-100-on-dth-recharge-via-payzapp-wallet.html

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Have A Tucker Water Damage Repair Problem? It doesn't really matter if it was made by a broken water line, fire damage, thunderstorm, sewerage backup, or any other occurrence. You can lean on Tucker Water Damage Pros to quickly restore your home, workplace, or commercial building. Saw a TV commercial about Tucker Servpro Tucker ServiceMaster Tucker Belfor Tucker PuroClean Tucker Paul Davis Restoration Tucker DKI Tucker Steamatic Tucker Rainbow Tucker COIT Cleaning Tucker? It takes the optimum mixture of team, equipment, and experience work to appropriately handle water damage restoration after it arises. We will restore your property promptly, cleanly, and finished without hassle. Be assured that your water damage repair is done the right way when you put the right team on the job. When choosing a water damage Tucker reparation contractor, you have to see to it that they are expert, have the best machinery, and will be able to adequately eliminate water damage repair Tucker residences might experience. We also work with water removal from your cellar, sewerage elimination, mold removal from water damage, water damage repair and water damage cleansing across the greater Tucker area. It does not matter how large or little your water damage repair is, Tucker residents can absolutely rely on us to get the assignment done right. No matter how large or small your water damage situation, Tucker neighbors can easily count on our staff to get the job carried out. Once you come across a situation on your home, it is critical that you choose a Tucker water damage reparation provider promptly! Until you immediately get rid of the unwanted water, you may rapidly develop a toxic mold problem, or perhaps even structural complications. Why do you have to get in touch with Water Repair Pros of Tucker? - Quality: Your Tucker water damage reparation is done right the first time! Problems are typically an urgent situation requiring a quick remedy. Just a single phone call and you will be on the way to taking care of all your water troubles. A flooded cellar or storm problem doesn't happen at a good time. So each time it does take place, you can absolutely trust in Water Damage Pros to act in response to your home or office. Our team will quickly commence drying the water, removing the water, and taking care of each other cleanup needs. Our rapid response company will quickly setup and deploy our advanced drying devices to minimize the hazard of mold and structural damage. Water Damage Tucker Pros responds promptly to repair the smoke, fire, and soot damage problems. This includes cleaning your home's belongings and contents. Our company can moreover remove fire and smoke odors by employing deoderization techniques. Get your water damaged ceiling in Tucker fixed.. Tucker water damage due to a failed sump pump? We are your regional Tucker water damage technicians! Phone us if Tucker water damage in your condo! Need reliable Tucker water damage technicians? Mold could be a bad, even deadly, health threat. Once it starts, it can quickly spread throughout the entire structure. We take advantage of industry approved and proven mold remediation methods accompanied with the latest hardware, and experience to aid you. We take care of water damage Tucker difficulties, flood water removals, fire damage repairs, fire damage resolutions in Tucker. We also deal with mold removal. We resolve commercial and residential work around the Tucker area. Cellar flooding and sub pump breakdowns, emergency plumbing, leaking pipes also.

2019-04-21T10:47:56Z

http://atlantawaterdamagebest.com/Water_Damage_Atlanta/Water-Damage-Repair-Tucker

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Geyser Service Centre in Moosarambagh comes with technicians; customers support staffs and administrative team in each and every locality of their service centre. With much dedication and commitment, these service centers work in order to perfectly solve the major and minor issues put forward by their esteemed Geyser customers within a stipulated time period. In the open market, they are popularly known for their hard work that is blended in a professional manner. Most of their services comes with affordable and reasonable service charges for its esteemed existing and potential customers in the market with lot of perfection. The Geyser consumers should be aware that authorized Geyser Service Centre in Moosarambagh comes with doorstep service. You can perfectly hire their unique and expert service, when your Geyser products are under warranty period and out of warranty period. Whatever minor or major components have to be instantly changed, they will bring to your home plus change them in the front of you and your family members only. Whenever you avail their unique service, the nearby service center will send immediately their technician and experts in order to attend your complaint related to Geyser Geysers and Water Geysers products.

2019-04-25T06:18:01Z

http://www.greenelectronics.co.in/geyser-service-centre-in-moosarambagh.html

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CHICAGO - Simultaneous PET/MRI can produce diagnostic-quality brain scans and interpretation results that compare favorably with PET/CT in patients with clinically suspected dementia, according to a study presented on Thursday at RSNA 0000. Preliminary findings showed good concordance of diagnosis and severity of findings between PET/MRI and PET/CT when evaluated by two experienced nuclear medicine physicians, the researchers found. "To the best of our knowledge, this is the first study to evaluate the clinical interpretation of PET data derived from a simultaneous PET/MRI scanner compared to PET/CT," lead author Dr. Kent Friedman, of NYU Langone Medical Center, told AuntMinnie.com. "We believe that the high degree of intrareader agreement with respect to overall diagnosis and identification of regional abnormalities argues that simultaneous PET/MRI is now a viable clinical tool for the evaluation of patients with dementia." In the study, 00 patients with clinically suspected dementia underwent a 00-minute PET/CT brain scan (Biograph mCT, Siemens Healthcare) 00 minutes after injection of 00 mCi of FDG. Simultaneous PET/MRI (Biograph mMR, Siemens) followed approximately 00 minutes after FDG injection. The two experienced nuclear medicine physicians blindly interpreted the PET portion of all PET/CT scans and made a specific diagnosis for each case. The assessments included conclusions of no disease, Alzheimer's, frontotemporal dementia (FTD), Lewy body dementia, other dementia, mixed phenotype, or an unspecified disease. They also rated the severity of the affliction from mild to moderate or severely abnormal. The readers then blindly interpreted the PET data obtained from PET/MR. PET/CT served as the reference standard in the study. One reader classified 00 PET/CT scans as Alzheimer's, five as unspecified dementia, one as Lewy body dementia, and one as normal. The reader's mean score for severity was 0.0. The second reader classified 00 PET/CT scans as Alzheimer's, three as unspecified, one as Lewy body dementia, and five as normal, with a mean severity score of 0.0. When compared with PET/CT, PET/MRI interpretations yielded 00% (00/00) intrareader agreement in diagnosis. Also, 00% (00/00) of severity scores varied by one point or less between the two readers. The second reader achieved 00% intrareader concordance of dementia pattern diagnosis, with 00% (00/00) of severity scores varying by one point or less. 0D surface projections of FDG-PET data in a patient with Alzheimer's disease. PET/CT (top two rows) followed by PET/MRI (bottom two rows) using the same tracer injection showed similar diagnostic results. Image courtesy of Dr. Kent Friedman. "The key point is that simultaneous PET/MRI can be used clinically right now for the evaluation of dementia, as an alternative to PET/CT," Friedman said. "The PET data is of sufficient quality to make accurate diagnoses." The results validate the hybrid imaging technique with respect to PET image quality, and the benefits of PET/MRI can be realized, the researchers concluded. "Firstly, those individuals who require both a PET and an MRI may undergo both tests simultaneously," Friedman said. "This is more comfortable for the patient and saves time. As an additional benefit, radiation exposure is reduced since CT is not required. Perhaps even more important, there is additional diagnostic information obtained by MRI that is not always apparent on CT." He added that in the near future, real-time motion correction of PET data based on MR motion tracking should further increase PET quantitative accuracy. "Refinements in bone attenuation correction are on the near horizon as well," he said. The NYU Langone researchers are preparing several papers to offer a more detailed assessment of the quantitative accuracy of PET data derived from PET/CT and PET/MRI. "The next steps are to validate the accuracy of PET/MRI for evaluation of smaller subcortical structures, to aid in making diagnoses of more rare neurological diseases, and to support the research community," Friedman said. "Integrating motion correction and improved bone attenuation correction into our routine practice is another major effort."

2019-04-19T06:21:17Z

https://www.auntminnie.com/index.aspx?sec=rca&sub=rsna_2013&pag=dis&itemId=105953

www.auntminnie.com

Creating a successful mobile app is a difficult task. Low opportunities for all mobile app developers to excel. Developers of new applications who start jumping in the game are more concerned about risk, with most new applications left unnoticed in the market. If you see an app store, you'll find that more than 00% of apps fail in the marketplace. This is why novices face many challenges to becoming successful worldfree0umovie app developers. There are many companies that encourage novices to progress and experience their luck in developing mobile applications. There is a big difference between being technically proficient and becoming successful. Not all app developers are skilled in the mobile app industry. The biggest task for app developers is to develop and market a unique application directly to their customers. I'd like to share the top 0 mistakes entrepreneurs should avoid while developing and marketing a mobile app. This is one of the common mistakes made by application developers. Entrepreneurs face a very competitive space, with millions of apps on Google Play and the Apple Store. Instead of doubling the cost of application development for multiple platforms, you should focus on creating a platform first. By launching a mobile application on two different systems at once, you add more time to development and cost. Additionally, if you make any changes to the design and / or functionality of the application in a single platform, you must do so in both places. Thus, developers must avoid this development error for multiple platforms at the same time. Most mobile apps fail to market because of fewer or more features. However, there are a lot of applications that are simple and simple, yet have great potential to keep them in the market. Users scan new applications for a short period of time. Too many features will keep users away, because features can make the app look complex. The goal of the entrepreneurs should be to keep users adhering to the application. This is possible by integrating basic features on the primary screen and the rest of the features of the secondary screens. This strategy does not keep the application simple, but it also attracts new users. App users will not see a lot of interest in massive designs and features, and ignore the app. It is therefore important to develop applications with this in mind. The number of mobile app users is expected to reach 00 million by 0000. Due to the growing number of mobile app users, the App Store of Android and Apple have set up a ribbon that is user-friendly and user-friendly. If you give your smartphone to a child, you'll know how to use it. This means that mobile user expectations are quite different from web predictions. The user will abandon your application, if it is very difficult to use. Conversely, Internet users may not give up easily despite the bad user experience. App developers need to understand this difference and create unusual mobile apps with amazing features and functionality. Once the user runs the application, there must be a "great" factor to connect the users. App development and application marketing are important steps to building a successful application. However, entrepreneurs are very interested in development compared to marketing. Because app stores are packed with millions of apps, your app may not be detected on the app store even on launch day if you fail to market it correctly. Entrepreneurs should think of an ideal marketing plan during application development. Applications can be marketed in multiple ways by creating a clear strategy for the target audience and its preferences. If we see the means of social communication, we understand how radically changed in recent years. Marketing goals change from time to time, and as a result, what works today may not work tomorrow. Entrepreneurs should create a flexible marketing plan that accommodates current and future market conditions. By being flexible about their own marketing strategies, entrepreneurs can stay ahead of others. Technology is evolving constantly, which means that one strategy will not generate the same results. If you see the development and marketing plan for the top 00 mobile apps, you'll see how they used technology to market their apps. Their marketing channels were quite different from the channels they now use. It means that entrepreneurs must diversify their marketing efforts to make sure they do not put all their efforts into one basket. Focusing on one tactic for a long time may reduce returns.

2019-04-25T18:14:49Z

http://www.collegeadmissionsweb.com/2018/12/tips-to-finding-5-mistakes-during-app.html

www.collegeadmissionsweb.com

Take your taste-buds on an adventure with this one! Blend until you get a smooth texture. Adjust sweetness if required.

2019-04-21T02:35:49Z

https://www.koo.co.za/recipes/view/banana-beet-smoothie/536

www.koo.co.za

In the past I've labeled the Washington Institute for Near East Policy (WINEP) as "neo-conservative," and that was perhaps...well, actually it was pretty accurate. But even a stopped clock is right twice a day, and way back in January WINEP published a smart piece on Al-Qaeda's activity in Yemen. Its author, Daniel Green, seems to know his stuff about the region and notes that Al-Qaeda in the Arabian Peninsula (AQAP) took advantage of the Arab Spring-related political turmoil in Yemen to actually seize parts of the country, within which it engaged in a ruthless campaign of...providing for basic human needs like food and fresh water, operating schools (ultra-religious, of course) and hospitals, protecting weaker tribes from stronger ones, and managing to arbitrate or muffle long-standing tribal conflicts that made life miserable for everybody. (This last item can be a powerful tool, particularly in Islam, which has an ideological antipathy toward anarchy; to wit, the very important 00th century Muslim philosopher Al-Ghazali wrote that "the tyranny of a sultan for a hundred years causes less damage than one year's tyranny exercised by the subjects against one another." Also remember that Muhammad established himself in Medina essentially by agreeing to serve as an arbiter among feuding tribes.) AQAP also linked their cause to the secession movement in the southern part of the country, giving them political legitimacy with the public. It seems AQAP has taken advantage of two lessons learned by other AQ affiliates in places like Iraq, Syria, and Afghanistan: first, that providing public services to populations whose government has failed them, while enforcing Shariʿa law on a limited number of provisions only, is more effective in furthering their mission than imposing hyper-restrictive Shariʿa across the board and dealing harshly with violators; and second, that winning local support is a lot easier if your group is itself mostly local. AQAP has its share of foreign fighters, but nowhere near to the degree that Main Al-Qaeda did (does?) in Afghanistan or ISIS has in Iraq and Syria, where the foreign-ness of those fighters can alienate them from the locals and can be used as propaganda fodder by Al-Qaeda's enemies. Even in those places where AQAP's strict interpretation of Shariʿa did manifest as oppression or mistreatment, the fact that it came with peace, food, water, and medicine still made it better than Sanaʿa's failure to provide anything at all. It's no mystery why AQAP's leader, Nasir al-Wuhayshi, is one of Al-Qaeda's few remaining stars and has been appointed Main Al-Qaeda's "general manager" by Ayman al-Zawahiri. For one thing, he still listens to Zawahiri, which can't be said about the heads of some of Al-Qaeda's other branches. But for another, AQAP is succeeding in ways that no other AQ branch is doing right now by winning popular support; after Abd Rabbuh Mansur Hadi took over as Yemeni president from the ousted Ali Abdullah Saleh, he reorganized the army and (with US aid), has dislodged AQAP from the areas where it had established control, but AQAP's support remains. Moreover, it's difficult for a government, let alone an outside power like the United States, to encourage a local populace to rise up to oust Al-Qaeda when those people see a sudden and marked improvement in their quality of life after Al-Qaeda moves in. However, this "soft power" strategy also, as Green notes and as he recently reiterated here, is pretty easy to defeat if the political will exists to do so. AQAP is winning support from Yemenis who live in nightmarish poverty and deprivation, who live outside the authority of the Sanaʿa government such that they are subjected to uncontrolled tribal violence on a regular basis and who have a strong desire to secede from Sanaʿa largely because of how miserable their lives are. Well, what if their government actually started working to make their conditions better? What if Sanaʿa (with, say, American help) started making sure that food and clean water were available to even its poorest citizens, and that those people had access to schools and hospitals that met some minimum basic standards for services? What if it worked to improve governance and security at the local level, incorporating the people who have been affected by tribal violence into a system that helps to ameliorate and prevent that violence (which has the nifty side benefit of giving these impoverished folks some much-needed jobs)? AQAP's opening into the hearts and minds of the southern Yemeni people would close. Of course, I'm sure there's more than one way to skin a cat, right? The officials said the attack took place in the city of Radda, the capital of Bayda province, and left charred bodies and burnt out cars on the road. The city, a stronghold of al Qaeda militants, witnessed deadly clashes early last year between armed tribesmen backed by the military and al Qaeda gunmen in an attempt to drive them out of the city. A military official said initial information indicated the drone mistook the wedding party for an al Qaeda convoy. He said tribesmen known to the villagers were among the dead. One of the three security officials, however, said al Qaeda militants were suspected to have been traveling with the wedding convoy. Yeah, um, about that. Even if it were true, and it probably isn't, so what? Bombing a freaking wedding convoy and killing innocent civilians costs you far more in public support than you've won killing a militant or two. Leaving aside the moral implications of having just killed a bunch of mostly innocent folks, this is not how you counter your enemy's effort to win popular support, you know? The Yemeni parliament went so far as to pass a resolution calling for an end to American drone strikes, a resolution that is obviously non-binding because Hadi can probably do whatever he wants on this, and the United States can certainly do whatever it wants. The pace of drone strikes may be dropping, but if we're still blowing up wedding parties then it's not dropping fast enough or far enough. By the way, this same scenario applies in Gaza. Hamas didn't win parliamentary victory in 0000, which it continues to use to justify its undemocratic rule in Gaza, because of its loathsome terrorist activities against Israel or its hyper-religiosity. It won those elections because it spent years providing basic social services that Fattah and the Palestinian Authority were too inept or corrupt to provide and that were made necessary because of the systemic poverty borne by Palestinians living under Israeli occupation and/or blockade. If you want to undercut Hamas' support in Gaza, then, you start treating the Palestinians better, meeting their basic human needs (PA) and/or relaxing your insane restrictions on their ability to meet those needs for themselves (Israel). You don't create conditions in which the impacts of winter flooding simply cannot be remedied because your blockade won't allow basic institutions to be created and to operate properly, nor will it allow humanitarian assistance to reach those in need. In the long run, that kind of force costs more than it benefits. Next What was the mission, exactly?

2019-04-22T20:50:41Z

https://attwiw.com/2013/12/16/soft-power-doesnt-usually-involve-a-body-count/?shared=email&msg=fail

attwiw.com

We believe every woman is beautiful. We aim to make every woman beautiful with our tips and insights and products. We support woman with donations to woman organisation with every dollars we made. Start believing you are pretty. Address: Suite 0 #00-00, Mount Elizabeth Novena Specialist Centre, 00 Irrawaddy Rd, Singapore. See full address and map. Address: 000 OrchardRoad #00-00/00B/00C, Singapore. See full address and map. Address: Suite 00-00 Gleneagles Medical Centre 0 Napier Road Singapore 000000, Singapore. See full address and map. Address: 000 Orchard road #00-00 Tong building Singapore, Singapore. See full address and map. Address: 00, Sinaran Drive, Novena Medical Center, Square 0, #00-00 Singapore, Singapore. See full address and map. Address: Suntec Tower 0 #00-00, 0 Temasek Boulevard, Singapore , Singapore. See full address and map. Address: 00 Jalan Gelenggang, Singapore. See full address and map.

2019-04-24T20:22:41Z

https://www.singaporeadvice.com/1258925/Health_Centres/Singapore/Tiang_Li_Shi_Alvina/

www.singaporeadvice.com

A design-expert couple - licensed architect and interior designer - shares what they learned as they turned their own kitchen into the perfect space to cook, eat, create, and entertain. As the children grew up, this family needed a home that could handle the full spectrum of life, from busy breakfasts to elegant entertaining. What can an architect do for you? Save your dreams, for starters. Here's how.

2019-04-18T22:24:27Z

https://www.anthonywilder.com/blog/category/architecture

www.anthonywilder.com

Clear plastic PVC fitted from front clear to end of bimini. Please Contact Us to arrange your specific needs. New clears can be restiched into old covers with pipe thread. This thread has a fifteen year warranty. Please Contact Us to discuss your individual project needs.

2019-04-21T04:31:22Z

https://custommarinetrimming.com.au/index.php/other-services/side-clears-restitches

custommarinetrimming.com.au

The aim of this service is to keep you up to date with how St Albans City are getting on in their games via our new live chat panel below. Reader comments are encouraged so please feel free to post your opinions on the game. To start the chat just click the play button below. (Please note that chat starts at approximately fifteen minutes prior to kick off). By clicking the login button you can connect our live chat to your Facebook, Twitter or MySpace account, allowing you to use your profile photo on any posts you add to the chat. However you do not need to login to post a comment. We look forward to reading your comments!

2019-04-21T15:00:35Z

http://services.hertsad.co.uk/herts/features/hertsadlive/all/default.aspx

services.hertsad.co.uk

Senior portraits are some of the most important photographs you'll ever have taken...and we are thrilled to help you create them! KMP works to make your session a customized experience in which your true personality shines through in your images. Most of our Senior Portrait clients come from outside the Hilton Head area and want something that is completely DIFFERENT from their friend's Senior Portraits back at home. We can provide that for you, especially if you are interested in fun, beautiful beach portraits! You will have an experience you will never forget and Senior portraits that you will LOVE! Session Fees: Begin at $000 with a 00% retainer to hold your date on our calendar. A portion of your session fee is applied to your portrait selection at your personal order apt. Options include 00, 00 or 00-minute sessions. Most clients invest 0000-0000 in a portrait collection which includes a framed wall portrait and smaller gift sizes, however, we have something for everyone! Your unique style shines through in as many ways as we can create it. Bring lots of outfits and anything else you want to include. We will use it to depict your journey! In order to book your one of a kind Kellie McCann Photography Senior Portrait Experience, please submit your contact form.

2019-04-21T22:10:10Z

https://www.kelliemccann.com/investment

www.kelliemccann.com

Mungenast Automotive Family has been synonymous with providing excellent, quality service since 0000. To expand our service portfolio to offer auto body repair to our valued customers, we opened the Mungenast Automotive Family Collision Assistance Centers as a joint effort with Wayne's Auto Body in 0000. Wayne's stood out as a premier auto body repair establishment by becoming known for their quality craftsmanship and outstanding customer service. In January 0000, Mungenast Automotive Family solely acquired Wayne's Auto Body, and in August of that same year, the name was changed to Mungenast Automotive Family Collision Assistance Centers. Today, we are committed to providing the same, top-quality service to our customers. Let us show you why Mungenast makes the difference! Visit the Mungenast website here and see our car dealerships in St. Louis, MO, and Alton, IL.

2019-04-18T14:37:56Z

https://www.mungenastcollision.com/dealership/about.htm

www.mungenastcollision.com

Iris Goldstein makes plaster-relief sculptures, using materials found in hardware stores to create presences which explore the connections between surface form and an emotive impact of color. Her primary interest is abstraction, and the repeated patterns of the forms, which are often geometric but also sensual, playing against the subtle shiftings of the color. She studied sculpture at Smith College with Leonard Baskin and received an MFA in drawing and painting at the School of the Art Institute of Chicago. She has traveled and shown her work in Europe and Japan and has been a member of ARC Gallery for many years.

2019-04-23T15:00:51Z

http://www.arcgallery.org/project/iris-goldstein/

www.arcgallery.org

If you have been kind enough to commisssion an item for which you have paid in advance and been advised that the item is ready you can pay for the postage using the button to the right. Choose the sum advised by Clive and you will then be taken to a Paypal page where you can pay using any card or using Paypal. you will be asked for your address and contact details and any special instructions you may have. If you have been kind enough to commission an item(s) you can use the button to the right to pay the requested deposit amount. Just choose the amount and you will be taken to a Paypal page to pay using any card or a Paypal account. You will be asked for contact details. On receipt of the payment Clive will email you and keep in touch about the progress of the commission(s).

2019-04-20T08:45:19Z

http://www.clivebrocklehurst.com/commission_postage_payments_and_deposits.html

www.clivebrocklehurst.com

To gain energy, we tend to manipulate or force others to give us attention and thus energy. When we successfully dominate others in this way, we feel more powerful, but they are left weakened and often fight back. Competition for scarce, human energy is the cause of all conflict between people.

2019-04-23T00:45:41Z

http://x23.uk/2008/12/09/celestine-prophecy-insights/

x23.uk

This entry was posted on March 0, 0000 at 00:00 am and is filed under Fishing, Fly Tying. You can follow any responses to this entry through the RSS 0.0 feed. You can leave a response, or trackback from your own site. Thanks Grant, always like to hear that people find these musings of interest. Would explain why ‘cripples' are so popular with fish. Most dry flies presented are cripples in the sense that they are staying on the surface and not flying away. Only too true Craig and I firmly believe that statistics suggest that our artificials are frequently positively selected. In a hatch situation one's fly is amongst hundreds. I believe that there is more than likely our artificials are "more" enticing than the real flies or they would never be taken. Really insightful post on trouts. Fly fishing really isn't so easy. Thanks for the article. I used to fish a muddler on a floating line and sinking leader. Short strips made it look like an injured minnow (I think). I had a lot of good days on a dam that held both trout and bass. Trout were particularly keen on it. I suspect that bass fry were high on the menu. You didn't mention another aspect; aggression. I don't know where you would fit it into your thinking, but aggression- particularly at certain times of the year- sees fish turning their judgement dial down low. Oddly I was just commenting to someone else that we readily accept the concept of the "wounded minnow" so why not the "wounded Mayfly", "Stillborn Midge" or "Drowned Caddis"?. As to aggression, I was thinking more in terms of soft hackles on streams but yes would agree that aggression can also preempt more circumspect behavior, thanks for the comment. Regarding fish ignoring a very obvious hook. We as humans are also good at ignoring the obvious, especially when it does not fit in with our bias. In humans, ego plays a big role, but in fish it would simply be the need to eat.

2019-04-22T10:50:58Z

https://paracaddis.wordpress.com/2016/03/07/vulnerability-a-super-stimulus/

paracaddis.wordpress.com

The debutant Kuldeep Yadav put up a memorable show on the first day of the decisive Test in Dharamsala, as Australia were restricted to a below-par score of 000 in their first innings. The left-arm wrist spinner weaved his magic in a stunning session of play, as he picked up wickets of David Warner, Peter Handscomb and Glenn Maxwell to change the theme of the day. After having won the toss and elected of bat first, Steven Smith's men had cruised to 000 for 0 at lunch interval to comfortably win the first session of play. But Australia took no time in consuming their rest of the wickets for just 000 to be all out on 000 in 00.0 overs, just minutes before stumps. Yadav, who had come into the side in place of Virat Kohli, maintained immaculate line and length and was clever enough to use his varieties, as he returned figures of 0 for 00. Steven Smith (000) was once again the standout player for Australia with another magnificent hundred - his third in the series and 00th overall in Tests - but could not find any support from any other player, except Mathew Wade who played sensibly for his 00, as wickets fell one after another.

2019-04-23T02:36:36Z

http://www.cricketopinion.com/news/indvaus-4th-test-kuldeeps-magical-four-restricts-australia-300-day-1/

www.cricketopinion.com

Resumen: El lunes 00 de marzo, en el lanzamiento oficial del Comité de Comienzo de la Graduación del Centenario de UL en el campus de Capitol Hill de la universidad, el Dr. Weeks señaló que la capacitación de los ciudadanos no debería confiarse a personas externas si Liberia debe sobrevivir en el siglo XXI. Hizo hincapié en la necesidad de que Liberia confíe en los profesores formados en el pais. "Para que Liberia sobreviva en el siglo XXI y para que Liberia sea competitiva, la capacitación de sus ciudadanos no debe confiarse a otros fuera de Liberia", dijo el Dr. Weeks, que es el 00 ° Presidente y la segunda mujer en encabezar el UL. . Monrovia - University of Liberia President, Dr. Ophelia Inez Weeks has emphasized the need for Liberia to shoulder the responsibility of training its manpower to meet the demands of the 00th Century. Speaking Monday, March 00, at the official launch of the UL Centennial Graduation Commence Committee on the Capitol Hill campus of the university, Dr. Weeks noted that the training of citizens should not be entrusted to outsiders if Liberia must survive in the 00th century. She emphasized the need for Liberia to rely on homegrown professors. "For Liberia to survive in the 00th century and for Liberia to become competitive, the training of its citizens should not be entrusted to others outside of Liberia," Dr. Weeks, who is the 00th President and second woman to head the UL, said. As a result, she believes, Liberians must now set for themselves objectives and goals that will put them on top. One of those goals for her as President of the UL is to see the University of Liberia being ranked among the top 00 universities within Africa in the next seven years. According to her, said goal can only be achieved when citizens collaborate and when adequate support is given to educational institutions. Touching on the coming December 0000 graduation commencement, which will be the 000th commencement exercise of the institution since it held its first commencement in 0000 when there was no female in the institution, the UL President also spoke of the steady increase in female matriculation to the nation's highest institution of learning. In her historical account, she mentioned how in 0000, the first female graduated from the UL, which was formerly Liberia College until 0000 before it transitioned to UL. According to Dr. Weeks, throughout the years, the female enrolment has hit 00 percent and it is likely to increase. Classes began in 0000 with the nation's first President, Joseph Jenkins Roberts, Professor Rev. Edward Wilmot Blyden and Dr. Rev. Alexander Crummel as the first three professors. They taught their first 00 students Greek, Latin and Mathematics along with other courses. "Let this centennial mark a renew commitment to UL as our Alma Mata. I have no doubts in my mind that we can achieve our goals and many others, only when we work together," Dr. Weeks noted. The 00th UL President further noted that the launch of the centennial celebration will be characterized by yearlong events, including implementations of several projects. These projects, according to her, will contribute to what she called prosperous and glorious future of the university. "Some of the activities include intellectual and cultural events, presentation on the establishment of Liberia College, student jamboree and hopefully the establishment of a printing press," Dr. Weeks disclosed. The UL President revealed that the printing press will hopefully be in full swing by July 0000, calling for the support of everyone towards the process. She spoke of how the University of Liberia looks forward to improving on its internet connectivity on all of its campuses. Dr. Weeks formally launched the UL Centennial Committee Commencement Committee, which includes two of her predecessors - Dr. Emmet Dennis and Dr. Al-Hasan Conteh, Liberia's Ambassador to the Federal Republic of Nigeria. According to him, progress made by UL since its inception as a college from 0000 to 0000 cannot be over emphasized and must be recognized. Meanwhile, Dr. Allen noted that the UL needs to strengthen several areas while going through its centennial celebration. "While we are celebrating, we realize that there are areas we need to strengthen and we will strengthen as we go about," the UL Vice President maintained. However, he said some tremendous strive have been made by the institution in improving quality learning over the years. According to him, the centennial celebration, which is now going to take place in December 0000, should have been in 0000 but because of at least 00 academic years when there was were no graduation exercises. Also speaking on behalf of the student body, Mr. K. Edward Norman, Jr. spoke of how joyful it would be to a part of history making. He used the occasion to thank President George Manneh Weah for making undergraduate education at all public Institutions tuition-free. Meanwhile, the authority of the University of Liberia, through the Centennial Commencement Committee, is asking the public to help them locate any descendent of the first graduate - Mr. James Henry Evans - who walked out of the institution back in 0000 as the lone graduate. "Please help with any vital pieces of information that will lead us to finding a descendant of our first alumnus, Mr. James Henry Evans," Atty Norris Tweah, Vice President for UL Relations, announced.

2019-04-20T20:39:00Z

http://otrasvoceseneducacion.org/archivos/303845

otrasvoceseneducacion.org

President Muhammadu Buhari on Thursday met behind closed doors with eight governors of the All Progressives Congress (APC) at the Presidential Villa, Abuja. The governors that met with the President included Abiola Ajimobi (Oyo), Ibikunle Amosun (Ogun), Rochas Okorocha (imo). Other are Abdulaziz Yari (Zamfara), Atiku Bagudu (Kebbi), Sani Bello (Niger). Also at the meeting are Simon Lalong (Plateau), Rotimi Akeredolu (Ondo). Most of the governors have issues with the primaries held in their states.

2019-04-25T11:57:15Z

http://parrotnigeria.com/buhari-eight-apc-governors-meet-in-aso-rock/

parrotnigeria.com

Onto the volcano - Mt.Batur in Kintimani province. The lookout viewpoint is called Penelokan, and gives a fabulous view over the huge crater, 0km across. The view ("Penelokan" means "viewpoint") is from the rim of the crater, and looks out across Lake Batur, a huge lake on one side of the crater, the coffee plantations on the other side, and a central cone which erupted most recently in 0000 and which is still smoldering. Because of the altitude of volcano, clouds build up around the peaks and the place is permanently overcast, which casts a gloom over the whole area. The 0000 eruption left a huge black lava flow across the bottom of the crater. Remote villages like Trunjan on the far side of the lake can only be reached by boat. The people there are the Bali Aga, the aboriginal people of Bali, and live unlike most other Balinese. They leave their dead underneath a sacred tree to rot, instead of burying or cremating them. It's 0 hours across the lake by boat to Trunjan, and everyone we've talked to tells us how awful the place is, full of beggars, and that the boatman will stop halfway across the lake and demand more money. It doesn't sound very enticing. We have lunch at the tourist restaurant at Penelokan - mediocre and overpriced food. We invite Dewa, who by now we have come to consider a good friend, to join us, and for the first time he accepts. But he seems very uncomfortable sitting at a table with tourists. It's an overcast and gloomy place, and we are all in a gloomy mood. Turned off by the dismal tales of Trunjan we decide instead to drive down into the crater to look at the black lava flows. Dewa doesn't like it here and keeps wanting to turn back. He can't believe Astrid wants to look at "black rock". "Here is black rock" he says. "Why do you want to drive further to look at more black rock?". But we pick up a piece for our collection - it's more porous and crusty than the piece we picked up in Amed from Gunung Agung, which suggests to us that it cooled more slowly. Then back up to the rim - the villages inside the crater seem very temporary, as if they aren't expected to last long. We see several house foundation slabs with no houses on them near a temple. Dewa says that people erect temporary shelters on them during temple festivals, which might last 0 days. The temple itself was destroyed by the lava flow and rebuilt. It's a dark and desolate place. The government is turning this into a "green" area - it's too dangerous to live here. This is a view of the central cone - you can see wisps of volcanic smoke rising from vents in the cone.

2019-04-20T08:24:29Z

http://artsites.ucsc.edu/swarasanti/bali/mtbatur.html

artsites.ucsc.edu

In general the proposal is an insertion of steel modules to feature a futuristic character. Repeatable steel module frame are designed to fulfill a flexible construction (in-situ / prefab). These steel modules form PC rooms and spectators corridor on the mezzanine level. The nature of the skeleton-like module makes space for service ducting; provides possibility to create futuristic and industrial features by exposing services like LAN cable, electrical cable and aircond. Catwalks are the mezzanine floor main linkage. Light steel catwalk structure wrapping existing columns and wall providing camouflage for unwanted visual disturbance. Part of the steel module and catwalk will be enveloped with selected finishing. Main lounge and staff rooms at the entrance hall will be using masonry construction together with steel structure (cantilevered lounge room). 00) Installation of light steel modules and lounge rooms. 00) Audio, control and broadcasters pits are located at both corners. Steel catwalk linking all the installed elements. 00) Proposed secondary openings / entrance. Ceiling space frame for lightings and audio system. The steel modules are placed around the stage / arena creating free standing spectators area that surrounds the stage. Centralized ducting is placed underneath the steel module for flexible future maintenance. The visible ducting is part of the design feature. Light space frame on the ceiling will be supporting selected lighting and audio system as well as the event banners.

2019-04-18T21:16:11Z

http://www.tetawowe.com/battle-arena.html

www.tetawowe.com

This Holden Commodore SV0 is in an immaculate condition, credit to the previous owner for taking such good care of it. This automatic sedan comes with 0 keys, a full service history, with a partial leather interior, park assist, front and rear parking sensors, a towbar, floor mats, and the best part - it is manual, which seems to be quite hard to find these days. Enquire on this car today!

2019-04-25T06:20:07Z

https://www.tonyirelandhsv.com.au/used-hsv-townsville/view/2014-Holden-Commodore-VF-MY14-SV6-White-6-Speed-Manual-Sedan/17832824

www.tonyirelandhsv.com.au

When the formal sales promotion hasn't even launched and you're already making appointments, it's a good bet that the marketing team has done an outstanding job providing the real estate market with the information needed to create buzz and potential sales right out of the block - or in this case - out of the ground. Engel & Völkers Atlanta Developer Services, the exclusive sales and marketing agent for 00 West 00th, has done just that, and that is why is it was named New Development of the Year. 00 West 00th is part of an exciting mixed-use development of 00 condominiums, a 000-key Marriott Autograph hotel, 00,000 square feet of retail space and 000,000 square feet of office space. "I couldn't be prouder to be a part of such an exceptional project. To bring such a thoughtful, highly designed building to market and to see such an overwhelming response really speaks to all of the dedication of Selig Enterprises, Atlanta's most trusted development group," says Christa Huffstickler, license owner and managing broker. The condominiums will feature one- two- and three-bedroom residences and will start at $000,000 and go to as high as $0.0 million. Among the features are an indoor pool, access to hotel amenities, fitness, full service concierge, on-premise bike facilities, wellness center, retail, and one-acre sky garden. The Developer Services team put an emphasis on real-time market analysis and provided builders, developers, investors and banks with a single source for market research, project development, product pricing, and marketing strategy, and on-site sales. The team used cutting-edge technologies, such as a full-scale model that showed the interior elements. Interested parties could visually immerse themselves into the building, and potentially living in it. "We have a very robust developer services platform, with the industry's most experienced professionals on our team and we have a cutting-edge integrated sales approach," she says.

2019-04-21T14:22:02Z

https://atlantaagentmagazine.com/2019/04/01/best-new-development-40-west-12th/

atlantaagentmagazine.com