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COVID-19 symptoms can sometimes persist for months
are heart complications likely in patients with COVID-19?
The cardiovascular system is also affected, with complications including myocardial injury, myocarditis, acute myocardial infarction, heart failure, dysrhythmias, and venous thromboembolic events. Current therapies for COVID-19 may interact with cardiovascular medications.
Neutral
COVID-19 symptoms can sometimes persist for months
are heart complications likely in patients with COVID-19?
the greater susceptibility of individuals with underlying cardiovascular conditions to develop more severe Covid-19 with higher mortality rate is likely to be confounded, in part, by age and the type of co-morbidities. Patients with heart failure or chronic kidney disease might show an excess risk
Neutral
hydroxychloroquine may limit spread of SARS-CoV-2 and morbidity and mortality of COVID-19 pandemic
does hydroxychloroquine treat COVID-19?
Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.
Supports
hydroxychloroquine may limit spread of SARS-CoV-2 and morbidity and mortality of COVID-19 pandemic
does hydroxychloroquine treat COVID-19?
the use of hydroxychloroquine alone was associated with increased mortality in COVID-19 patients.
Refutes
hydroxychloroquine may limit spread of SARS-CoV-2 and morbidity and mortality of COVID-19 pandemic
does hydroxychloroquine treat COVID-19?
Since COVID-19 outbreak, various agents have been tested but no proven effective therapies have been identified.
Refutes
hydroxychloroquine may limit spread of SARS-CoV-2 and morbidity and mortality of COVID-19 pandemic
does hydroxychloroquine treat COVID-19?
HCQ should be prescribed as a part of treatment for critically ill COVID-19 patients, with possible outcome of saving lives.
Supports
Vitamin D reduces infection and impact of COVID-19
Does Vitamin D impact COVID-19 prevention and treatment?
ecological investigation on 51 countries including 408,748 participants, analyses indicated no correlation between vitamin D levels and recovery rate (r= 0.041) as well as mortality rate (r=-0.073) globally.
Refutes
Vitamin D reduces infection and impact of COVID-19
Does Vitamin D impact COVID-19 prevention and treatment?
testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.
Supports
Vitamin D reduces infection and impact of COVID-19
Does Vitamin D impact COVID-19 prevention and treatment?
A significant negative correlation (p=0.033) has been observed between mean vitamin D levels and COVID-19 cases per one million population in European countries.
Supports
Vitamin D reduces infection and impact of COVID-19
Does Vitamin D impact COVID-19 prevention and treatment?
Vitamin D dose was not significantly associated with testing positive for COVID-19.
Refutes
While most of the drug treatments (the FDA-approved drugs lopinavir-ritonavir, hydroxychloroquine sulfate, and emtricitabinetenofovir against SARS-CoV-2 infection) marginally reduced clinical symptoms, they did not reduce virus titers, with the exception of emtricitabine-tenofovir treatment, which led to diminished virus titers in nasal washes at 8 dpi.
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
Thus, our goal is to test the most active antivirals identified in adequate animal models infected with SARS-CoV-2, to add more information about possible in vivo efficacy. In turn, successful antivirals could be tested in clinical trials as treatments for infected patients, but also as pre-exposure prophylaxis to avoid novel infections until an effective and safe vaccine is developed.
Neutral
While most of the drug treatments (the FDA-approved drugs lopinavir-ritonavir, hydroxychloroquine sulfate, and emtricitabinetenofovir against SARS-CoV-2 infection) marginally reduced clinical symptoms, they did not reduce virus titers, with the exception of emtricitabine-tenofovir treatment, which led to diminished virus titers in nasal washes at 8 dpi.
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
The results suggest the effectiveness of Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir as potent drugs against SARS-CoV-2 since they tightly bind to its RdRp. In addition, the results suggest guanosine derivative (IDX-184), Setrobuvir, and YAK as top seeds for antiviral treatments with high potential to fight the SARS-CoV-2 strain specifically.
Neutral
While most of the drug treatments (the FDA-approved drugs lopinavir-ritonavir, hydroxychloroquine sulfate, and emtricitabinetenofovir against SARS-CoV-2 infection) marginally reduced clinical symptoms, they did not reduce virus titers, with the exception of emtricitabine-tenofovir treatment, which led to diminished virus titers in nasal washes at 8 dpi.
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.
Neutral
While most of the drug treatments (the FDA-approved drugs lopinavir-ritonavir, hydroxychloroquine sulfate, and emtricitabinetenofovir against SARS-CoV-2 infection) marginally reduced clinical symptoms, they did not reduce virus titers, with the exception of emtricitabine-tenofovir treatment, which led to diminished virus titers in nasal washes at 8 dpi.
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
We show that a high (5106 pfu) and medium (5104 pfu) dose of SARS-CoV-2 induces consistent upper respiratory tract (URT) viral RNA shedding in both groups of six challenged animals, whilst a low dose (5102 pfu) resulted in only one of six displaying signs of URT viral RNA replication.
Neutral
camostat mesylate inhibited infection of important target cells - human lung epithelial cells,
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
Several efforts are currently made to find a treatment for COVID-19 patients. So far, several anti-viral and immunosuppressive or immunomodulating drugs have demonstrated some efficacy on COVID-19 both in vitro and in animal models as well as in cases series.
Neutral
camostat mesylate inhibited infection of important target cells - human lung epithelial cells,
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
Thus, our goal is to test the most active antivirals identified in adequate animal models infected with SARS-CoV-2, to add more information about possible in vivo efficacy. In turn, successful antivirals could be tested in clinical trials as treatments for infected patients, but also as pre-exposure prophylaxis to avoid novel infections until an effective and safe vaccine is developed.
Neutral
camostat mesylate inhibited infection of important target cells - human lung epithelial cells,
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
At this point, the data here presented on hydroxychloroquine either alone or combined with azithromycin (together with previously reported in vivo data in macaques and ferrets) provide no scientific basis for further use of the drug in humans.
Neutral
camostat mesylate inhibited infection of important target cells - human lung epithelial cells,
are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?
When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.
Neutral
mask-wearing can lessen COVID-19 severity
Can face masks protect me from the coronavirus disease?
In this study, we demonstrated, using avian coronavirus of infectious bronchitis virus to mimic SARSCoV2, that medical masks and N95 masks remained their blocking efficacy after being steamed on boiling water even for 2 hours.
Supports
mask-wearing can lessen COVID-19 severity
Can face masks protect me from the coronavirus disease?
Together, this study suggested that medical masks are adequate for use on most social occasions, and both medical masks and N95 masks can be reused for a few days with steam decontamination between use.
Supports
mask-wearing can lessen COVID-19 severity
Can face masks protect me from the coronavirus disease?
Wearing medical masks or N95 masks (namely N95 respirators) can slow the virus spread and reduce the infection risk.
Supports
mask-wearing can lessen COVID-19 severity
Can face masks protect me from the coronavirus disease?
It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2).
Supports
People wearing face coverings will take in fewer coronavirus particles, evidence suggests, making disease less severe.
Can face masks protect me from the coronavirus disease?
It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2).
Supports
People wearing face coverings will take in fewer coronavirus particles, evidence suggests, making disease less severe.
Can face masks protect me from the coronavirus disease?
and 3) provides suggestion that the public should wear the mask during COVID-19 pandemic according to local context.
Supports
People wearing face coverings will take in fewer coronavirus particles, evidence suggests, making disease less severe.
Can face masks protect me from the coronavirus disease?
We find that the critical mask adherence is 5 per 100 when 80% wear face masks.
Supports
People wearing face coverings will take in fewer coronavirus particles, evidence suggests, making disease less severe.
Can face masks protect me from the coronavirus disease?
Our results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals.
Supports
The virus survives better in cold
how does the coronavirus respond to changes in the weather
The current study focuses on the relationship between environmental parameters and the growth rate of COVID-19. The statistical analysis suggests that the temperature changes retarded the growth rate and found that -6.28C and +14.51C temperature is the favorable range for COVID-19 growth.
Supports
The virus survives better in cold
how does the coronavirus respond to changes in the weather
Temperature is the most influential parameter that reduces the growth at the rate of 13-16 cases/day with a 1{degrees}C rise in temperature
Supports
The virus survives better in cold
how does the coronavirus respond to changes in the weather
We show that the delay between exposure and detection of infection complicates the estimation of weather impact on COVID-19 transmission, potentially explaining significant variability in results to-date
Neutral
The virus survives better in cold
how does the coronavirus respond to changes in the weather
In the southern cities, the ambient temperature and air pollution have a negative interactive effect on COVID-19 transmission, implying that rising temperature restrains the facilitating effects of air pollution and that they jointly lead to a decrease in new confirmed cases.
Supports
there is currently no evidence that animals, including pets, can be infected with the coronavirus, and no evidence that animals can spread the virus
Can pets get the coronavirus disease?
It is now accepted that the wild fauna, probably bats, constitute the initial reservoir of the virus, but little is known about the role pets can play in the spread of the disease in human communities, knowing the ability of SARS-CoV-2 to infect some domestic animals.
Refutes
A more specialized mask, known as an N95 respirator, can protect against the new coronavirus, also called SARS-CoV-2.
Can face masks protect me from the coronavirus disease?
Together, this study suggested that medical masks are adequate for use on most social occasions, and both medical masks and N95 masks can be reused for a few days with steam decontamination between use.
Supports
A more specialized mask, known as an N95 respirator, can protect against the new coronavirus, also called SARS-CoV-2.
Can face masks protect me from the coronavirus disease?
2) addresses controversies surrounding the mask from perspectives of attitude, effectiveness, and necessity of wearing the mask with evidence that the use of mask would effectively interrupt the transmission of infectious diseases in both hospital settings and community settings;
Supports
A more specialized mask, known as an N95 respirator, can protect against the new coronavirus, also called SARS-CoV-2.
Can face masks protect me from the coronavirus disease?
We find that the critical mask adherence is 5 per 100 when 80% wear face masks.
Supports
A more specialized mask, known as an N95 respirator, can protect against the new coronavirus, also called SARS-CoV-2.
Can face masks protect me from the coronavirus disease?
Our results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals.
Supports
recovered COVID-19 patients have protection for 3 months
Are you immune to COVID-19 after recovering from it?
A multiple sclerosis patient infected by SARS-CoV-2 during fingolimod therapy was hospitalized with moderate clinical features, and recovered in 15 days.
Neutral
recovered COVID-19 patients have protection for 3 months
Are you immune to COVID-19 after recovering from it?
Recently, an increasing number of reports have indicated that a few patients who were believed to have recovered from COVID-19 initially tested negative but later tested positive.
Refutes
recovered COVID-19 patients have protection for 3 months
Are you immune to COVID-19 after recovering from it?
Several studies suggest that acquired immunity may protect upon further exposure to SARSCOV2
Supports
recovered COVID-19 patients have protection for 3 months
Are you immune to COVID-19 after recovering from it?
we serially analysed immune responses in 113 COVID-19 patients with moderate (non-ICU) and severe (ICU) disease.
Neutral
Flu: Flu viruses can cause mild to severe illness, including common signs and symptoms listed above. COVID-19: Other signs and symptoms of COVID-19, different from flu, may include change in or loss of taste or smell.
How does the coronavirus differ from seasonal flu?
Temporal analyses of laboratory results revealed that compared to influenza, patients with COVID-19 exhibited a continued increase in the white blood cell count, rapid decline of hemoglobin, more rapid increase in blood urea nitrogen (BUN) and D-dimer, and higher level of alanine transaminase, C-reactive protein, ferritin, and fibrinogen.
Supports
Flu: Flu viruses can cause mild to severe illness, including common signs and symptoms listed above. COVID-19: Other signs and symptoms of COVID-19, different from flu, may include change in or loss of taste or smell.
How does the coronavirus differ from seasonal flu?
There are significant differences in the clinical and laboratory courses between COVID-19 and influenza.
Supports
there is no risk of being infected by groceries and packages that we have delivered
touching a contaminated surface will not make you sick
The most common coronaviruses may well survive or persist on surfaces for up to one month.
Neutral
there is no risk of being infected by groceries and packages that we have delivered
touching a contaminated surface will not make you sick
Inefficient human-to-human transmission of zoonotic strains may initially limit the spread of transmission, but an infection may be contracted by touching contaminated surfaces.
Refutes
there is no risk of being infected by groceries and packages that we have delivered
touching a contaminated surface will not make you sick
Most viruses from the respiratory tract, such as coronaviruses, influenza, SARS-CoV, or rhinovirus, can persist on surfaces for a few days.
Neutral
there is no risk of being infected by groceries and packages that we have delivered
touching a contaminated surface will not make you sick
Our findings of extensive viral RNA contamination of surfaces and air across a range of acute healthcare settings in the absence of cultured virus underlines the potential risk from surface and air contamination in managing COVID-19, and the need for effective use of PPE, social distancing, and hand/surface hygiene.
Neutral
Can you boost your immune system to fight COVID-19? This is the question on everyone's mind as we face a worldwide crisis.
will SARS-CoV2 infected people develop immunity?
In this study, we collected blood from COVID-19 patients who have recently become virus-free and therefore were discharged, and analyzed their SARS-CoV-2-specific antibody and T cell responses. We observed SARS-CoV-2-specific humoral and cellular immunity in the patients. Both were detected in newly discharged patients, suggesting both participate in immune-mediated protection to viral infection.
Neutral
Can you boost your immune system to fight COVID-19? This is the question on everyone's mind as we face a worldwide crisis.
will SARS-CoV2 infected people develop immunity?
The number of these epitopes and the prevalence of the common coronaviruses suggest that a large part of the world population has some degree of specific immunity against SARS-CoV-2 already, even without having been infected by that virus.
Neutral
Can you boost your immune system to fight COVID-19? This is the question on everyone's mind as we face a worldwide crisis.
will SARS-CoV2 infected people develop immunity?
Thus both qualitative and quantitative features of B and T cell immunity to spike constitute informative biomarkers of the protective potential of novel SARS-CoV-2 vaccines.
Neutral
Can you boost your immune system to fight COVID-19? This is the question on everyone's mind as we face a worldwide crisis.
will SARS-CoV2 infected people develop immunity?
we discovered evidence that SARS-CoV-2, along with related coronaviruses, used mutations to evade attack from the human immune system. Overall, we present an immunological resource for SARS-CoV-2 that could promote both therapeutic development and mechanistic research.
Neutral
The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces
touching a contaminated surface will not make you sick
Frequent touching of contaminated surfaces in public areas is therefore a potential route of SARS-CoV-2 transmission.
Neutral
The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces
touching a contaminated surface will not make you sick
Coronavirus disease 2019 (COVID-19) originated in the city of Wuhan, Hubei Province, Central China
Neutral
The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces
touching a contaminated surface will not make you sick
This provides evidences strongly supporting scientific hypotheses that bats and pangolins are probable hosts for the COVID-19 virus. At the whole genome analysis level, our findings also indicate that bats are more likely the hosts for the COVID-19 virus than pangolins.
Neutral
The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces
touching a contaminated surface will not make you sick
It was found that 83% and 77% of the bedside surfaces of MRSA-positive and MRSA-negative patients respectively were contaminated with staphylococci at 08:00 hours, and that the staphylococcal concentrations increased by 80% at 1200 h over a 4-hour period with routine ward and clinical activities.
Supports
As a smoker, you or the people who care about you may be worried about a connection between COVID-19 and smoking.
Can smoking help in preventing COVID-19?
Cannabis thus joins tobacco as a SARS2-CoV-2 risk factor.
Supports
As a smoker, you or the people who care about you may be worried about a connection between COVID-19 and smoking.
Can smoking help in preventing COVID-19?
Cannabis smoking is linked with poor respiratory health, immunosuppression and multiple contaminants. Potential synergism between the two epidemics would represent a major public health convergence. Cigarettes were implicated with disease severity in Wuhan, China.
Supports
As a smoker, you or the people who care about you may be worried about a connection between COVID-19 and smoking.
Can smoking help in preventing COVID-19?
Conclusions This representative population sample will, to our knowledge, present the first comprehensive examination of the association between smoking, nicotine use without smoking, respiratory disease, and severity of COVID-19.
Neutral
As a smoker, you or the people who care about you may be worried about a connection between COVID-19 and smoking.
Can smoking help in preventing COVID-19?
Data indicate CVIR demonstrates significant trends across cannabis use intensity quintiles and with relaxed cannabis legislation. Recent cannabis use is independently predictive of CVIR in bivariate and multivariable adjusted models and intensity of use is interactively significant.
Supports
A face covering can prevent people who are asymptomatic carriers of Covid-19 from spreading the virus
Can wearing masks help in preventing the spread of the coronavirus disease?
Wearing medical masks or N95 masks (namely N95 respirators) can slow the virus spread and reduce the infection risk.
Supports
A face covering can prevent people who are asymptomatic carriers of Covid-19 from spreading the virus
Can wearing masks help in preventing the spread of the coronavirus disease?
This study 1) illustrates transmission routes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); 2) addresses controversies surrounding the mask from perspectives of attitude, effectiveness, and necessity of wearing the mask with evidence that the use of mask would effectively interrupt the transmission of infectious diseases in both hospital settings and community settings; and 3) provides suggestion that the public should wear the mask during COVID-19 pandemic according to local context.
Supports
A face covering can prevent people who are asymptomatic carriers of Covid-19 from spreading the virus
Can wearing masks help in preventing the spread of the coronavirus disease?
Evidence that face masks provide effective protection against respiratory infections in the community is scarce. However, face masks are widely used by health workers as part of droplet precautions when caring for patients with respiratory infections. It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2).
Supports
A face covering can prevent people who are asymptomatic carriers of Covid-19 from spreading the virus
Can wearing masks help in preventing the spread of the coronavirus disease?
Face masks are an avenue to curb the spread of coronavirus, but few people in Western societies wear face masks.
Supports
Coronavirus: No proof yet that pets can get COVID-19 from owners
Can animals spread COVID-19 to people?
There is evidence that SARS-CoV-2 can infect felines, dogs and minks, and there is evidence of human-to-animal infection.
Refutes
Coronavirus: No proof yet that pets can get COVID-19 from owners
Can animals spread COVID-19 to people?
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)--the virus that causes coronavirus disease (COVID-19)--has been detected in domestic dogs and cats, raising concerns of transmission from, to, or between these animals.
Refutes
Coronavirus: No proof yet that pets can get COVID-19 from owners
Can animals spread COVID-19 to people?
Although animal-to-animal transmission has been shown to be possible, there is no evidence of animal-to-human transmission.
Refutes
Coronavirus: No proof yet that pets can get COVID-19 from owners
Can animals spread COVID-19 to people?
There are now many reports of SARS-CoV-2 positive cases in dogs, cats, tigers, lion, and minks. Experimental data showed ferrets and cats are highly susceptible to SARS-CoV-2 as infected by virus inoculation and can transmit the virus directly or indirectly by droplets or airborne route.
Refutes
hand dryers are effective in killing the new covid-19
what hand sanitizers kill COVID-19?
There is currently no vaccine for COVID-19, leaving governments and public health agencies with little defense against the virus aside from advising or enforcing best practices for virus transmission prevention, which include hand-washing, physical distancing, use of face covers, and use of effective disinfectants.
Neutral
hand dryers are effective in killing the new covid-19
what hand sanitizers kill COVID-19?
Efficient SARS-CoV-2 inactivation was demonstrated for all tested alcohol-based disinfectants. These findings show the successful inactivation of SARS-CoV-2 for the first time and provide confidence in its use for the control of COVID-19.
Neutral
hand dryers are effective in killing the new covid-19
what hand sanitizers kill COVID-19?
Most alcohol based hand sanitizers are effective at inactivating enveloped viruses, including coronaviruses.
Neutral
hand dryers are effective in killing the new covid-19
what hand sanitizers kill COVID-19?
The index of India has remained very low (161) so far, mainly due to early implementation of social lockdown, social distancing, and sanitizing hands.
Neutral
IL-17A helps trigger immune system response during early infection and INF-g combats replication of the virus. Higher levels of the two molecules may be associated with better outcomes in COVID-19 patients
will SARS-CoV2 infected people develop immunity?
Based on animal experiments, already acquired data on other coronavirus types and plausibility assumptions, it can be assumed that seroconverted patients have an immunity of limited duration and only a very low risk of reinfection.
Neutral
IL-17A helps trigger immune system response during early infection and INF-g combats replication of the virus. Higher levels of the two molecules may be associated with better outcomes in COVID-19 patients
will SARS-CoV2 infected people develop immunity?
we discovered evidence that SARS-CoV-2, along with related coronaviruses, used mutations to evade attack from the human immune system. Overall, we present an immunological resource for SARS-CoV-2 that could promote both therapeutic development and mechanistic research.
Neutral
IL-17A helps trigger immune system response during early infection and INF-g combats replication of the virus. Higher levels of the two molecules may be associated with better outcomes in COVID-19 patients
will SARS-CoV2 infected people develop immunity?
Distinguishing pre-existing and de novo antibody responses to SARS-CoV-2 will be critical for serology, seroprevalence and vaccine studies, as well as for our understanding of susceptibility to and natural course of SARS-CoV-2 infection.
Neutral
IL-17A helps trigger immune system response during early infection and INF-g combats replication of the virus. Higher levels of the two molecules may be associated with better outcomes in COVID-19 patients
will SARS-CoV2 infected people develop immunity?
Distinguishing pre-existing and de novo antibody responses to SARS-CoV-2 will be critical for serology, seroprevalence and vaccine studies, as well as for our understanding of susceptibility to and natural course of SARS-CoV-2 infection.
Neutral
Although there have not been reports of pets or other animals becoming sick with 2019-nCoV, several types of coronaviruses can cause illness in animals and spread between animals and people.
Can coronaviruses spread from people to animals?
Therefore, there is a possibility of spreading SARS-CoV-2 through domestic pets. There are now many reports of SARS-CoV-2 positive cases in dogs, cats, tigers, lion, and minks.
Refutes
Although there have not been reports of pets or other animals becoming sick with 2019-nCoV, several types of coronaviruses can cause illness in animals and spread between animals and people.
Can coronaviruses spread from people to animals?
Although coronavirus infections in pets are known to be predominantly related to the gastrointestinal tract, it has been observed that there are human-to-animal transmissions in this outbreak and some animals have similar symptoms to humans.
Refutes
Although there have not been reports of pets or other animals becoming sick with 2019-nCoV, several types of coronaviruses can cause illness in animals and spread between animals and people.
Can coronaviruses spread from people to animals?
A novel coronavirus emerged in human populations and spread rapidly to cause the global coronavirus disease 2019 pandemic.
Neutral
Although there have not been reports of pets or other animals becoming sick with 2019-nCoV, several types of coronaviruses can cause illness in animals and spread between animals and people.
Can coronaviruses spread from people to animals?
Coronaviruses, which were generally considered harmless to humans before 2003, have appeared again with a pandemic threatening the world since December 2019 after the epidemics of SARS and MERS.
Neutral
Excessive alcohol use can weaken the immune system
Can drinking alcohol help in preventing COVID-19?
Is drinking a healthy way of coping? No.
Supports
Excessive alcohol use can weaken the immune system
Can drinking alcohol help in preventing COVID-19?
While it remains much too early to determine precisely how alcohol use might affect risk for or progression of COVID19, any efforts to connect the dots from past alcohol research would suggest it wise for nondrinkers and lowrisk drinkers to maintain that status during this public health crisis.
Supports
Coronavirus may have originated in bats or pangolins.
what is the origin of COVID-19
Zhou et al (1) mentioned that 'Direct contact with intermediate host animals or consumption of wild animals was suspected to be the main route of SARSCoV2 transmission.
Supports
Coronavirus may have originated in bats or pangolins.
what is the origin of COVID-19
This provides evidences strongly supporting scientific hypotheses that bats and pangolins are probable hosts for the COVID-19 virus. At the whole genome analysis level, our findings also indicate that bats are more likely the hosts for the COVID-19 virus than pangolins.
Supports
Coronavirus may have originated in bats or pangolins.
what is the origin of COVID-19
A novel coronavirus (severe acute respiratory syndrome-CoV-2) that initially originated from Wuhan, China, in December 2019 has already caused a pandemic.
Neutral
Coronavirus may have originated in bats or pangolins.
what is the origin of COVID-19
This paper investigates the COVID-19 virus origin by using artificial intelligence (AI) and raw genomic sequences of the virus.
Neutral
animals develope fever as an evolutionary response to infection.
Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?
For NSAIDs, there is no clear scientific evidence linking ibuprofen and other NSAIDs to worsening of COVID-19; however, it seems prudent to continue them, if necessary to control pericarditis, and on the other hand, to prefer paracetamol for fever and systemic symptoms related to COVID-19.
Refutes
animals develope fever as an evolutionary response to infection.
Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?
At this time, there is no supporting evidence to discourage the use of ibuprofen.
Refutes
animals develope fever as an evolutionary response to infection.
Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?
In the setting of pericardial diseases, there are two possible different scenarios to consider: the patient being treated for pericarditis who subsequently becomes infected with SARS-CoV-2, and the patient with COVID-19 who develops pericarditis or pericardial effusion.
Neutral
animals develope fever as an evolutionary response to infection.
Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?
CONCLUSIONS: In this cohort of COVID-19 patients, ibuprofen use was not associated with worse clinical outcomes, compared with paracetamol or no antipyretic.
Refutes
the virus could remain stable for long periods at 4 degrees C
touching a contaminated surface will not make you sick
The contaminated surface environment in hospitals plays an important role in the transmission of several key nosocomial pathogens including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp., Clostridium difficile, Acinetobacter spp., and norovirus.
Neutral
the virus could remain stable for long periods at 4 degrees C
touching a contaminated surface will not make you sick
We report here that pathogenic human coronavirus 229E remained infectious in a human lung cell culture model following at least 5 days of persistence on a range of common nonbiocidal surface materials, including polytetrafluoroethylene (Teflon; PTFE), polyvinyl chloride (PVC), ceramic tiles, glass, silicone rubber, and stainless steel.
Neutral
the virus could remain stable for long periods at 4 degrees C
touching a contaminated surface will not make you sick
Contacting contaminated nonfabric surfaces may pose an indirect contact risk up to three orders of magnitude higher than that of contacting contaminated fabric surfaces.
Neutral
the virus could remain stable for long periods at 4 degrees C
touching a contaminated surface will not make you sick
In this new study, human coronavirus 229E was rapidly inactivated on a range of copper alloys (within a few minutes for simulated fingertip contamination) and Cu/Zn brasses were very effective at lower copper concentration.
Neutral
face masks can provide a temporary barrier against viruses
Can face masks protect me from the coronavirus disease?
Our results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals.
Supports
face masks can provide a temporary barrier against viruses
Can face masks protect me from the coronavirus disease?
We also demonstrated that three brands of medical masks blocked over 99% viruses in aerosols. The avian coronavirus was completely inactivated after being steamed for 5 minutes.
Supports
face masks can provide a temporary barrier against viruses
Can face masks protect me from the coronavirus disease?
Wearing medical masks or N95 masks (namely N95 respirators) can slow the virus spread and reduce the infection risk.
Supports
face masks can provide a temporary barrier against viruses
Can face masks protect me from the coronavirus disease?
and 3) provides suggestion that the public should wear the mask during COVID-19 pandemic according to local context.
Supports
Blood Pressure Meds Can Affect COVID-19 Care
are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?
The present study has found that the use of ACE inh/ARBs therapy might be associated with an increased in-hospital mortality in patients who were diagnosed with Covid-19 pneumonia.
Neutral
Blood Pressure Meds Can Affect COVID-19 Care
are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?
among patients who were diagnosed with COVID-19, ACEI/ARB use was not associated with increased risk of hospital admission.
Refutes
Blood Pressure Meds Can Affect COVID-19 Care
are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?
This has led to the hypothesis that use of ACEIs and ARBs may increase the risk of developing severe COVID-19.
Supports
Blood Pressure Meds Can Affect COVID-19 Care
are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?
Our results strongly support the recommendation that ACEI and ARB should be continued in the population and in COVID-19 positive patients, reinforcing the position of several scientific societies.
Neutral
COVID-19 spreads less commonlythrough contact with contaminated surfaces, and rarely between people and animals.
Can animals spread COVID-19 to people?
ferrets and cats are highly susceptible to SARS-CoV-2 as infected by virus inoculation and can transmit the virus directly or indirectly by droplets or airborne routes.
Supports