jarod0411/cm_v6_idx8 · Datasets at Hugging Face

prompt stringlengths 49 261	first_mask_count int64 0 16	first_start_index int64 0 198	first_mask_gen_count int64 1 16	first_mask_tokens stringlengths 0 16	first_mask_gen_count_real int64 0 29	generated_smiles stringlengths 12 233	original_smiles stringlengths 12 223	generated_tokens stringlengths 0 29
<\|startoftext\|><L>COc1ccc(/C<mask_1:1>c2ncnc3[nH]cnc23)c(OC)c1<mask_1:1>	4	10	1	=N/N	1	COc1ccc(/CNc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	N
<\|startoftext\|><L>COc1ccc(/C=N<mask_1:5>Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:5>	1	12	5	/	5	COc1ccc(/C=N/NCCCNc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	/NCCC
<\|startoftext\|><L>COc1ccc(/C=N/Nc2ncnc3[nH]c<mask_1:5>)c(OC)c1<mask_1:5>	4	26	5	nc23	4	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	nc23
<\|startoftext\|><L>COc1ccc(/C=N/Nc2ncn<mask_1:4>]cnc23)c(OC)c1<mask_1:4>	5	19	4	c3[nH	5	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	c3[nH
<\|startoftext\|><L>COc1ccc(/<mask_1:5>N/Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:5>	2	9	5	C=	5	COc1ccc(/C(C)=N/Nc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	C(C)=
<\|startoftext\|><L>COc1ccc(<mask_1:4>C=N/Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:4>	1	8	4	/	4	COc1ccc(C=C/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	C=C/
<\|startoftext\|><L>COc1ccc(/C<mask_1:2>2ncnc3[nH]cnc23)c(OC)c1<mask_1:2>	5	10	2	=N/Nc	2	COc1ccc(/CNc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	Nc
<\|startoftext\|><L>COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(<mask_1:3>OC)c1<mask_1:3>	0	33	3		3	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OCCOC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	OCC
<\|startoftext\|><L>COc1ccc(<mask_1:5>=N/Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:5>	2	8	5	/C	5	COc1ccc(/C(C)=N/Nc2ncnc3[nH]cnc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	/C(C)
<\|startoftext\|><L>COc1ccc(/C=N/Nc2ncnc3[nH]c<mask_1:4>nc23)c(OC)c1<mask_1:4>	0	26	4		4	COc1ccc(/C=N/Nc2ncnc3[nH]c(Br)nc23)c(OC)c1	COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1	(Br)
<\|startoftext\|><L>Cc1nc([C@@H]2<mask_1:3>(C(=O)C3=COCCC3)C2)no1<mask_1:3>	4	13	3	CCCN	3	Cc1nc([C@@H]2CCN(C(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	CCN
<\|startoftext\|><L>Cc1nc(<mask_1:5>[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:5>	0	6	5		5	Cc1nc(CN(C)[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	CN(C)
<\|startoftext\|><L>Cc1nc([C@@H]2CC<mask_1:2>N(C(=O)C3=COCCC3)C2)no1<mask_1:2>	1	15	2	C	2	Cc1nc([C@@H]2CCCCN(C(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	CC
<\|startoftext\|><L>Cc1nc([C@@H]2C<mask_1:5>C(=O)C3=COCCC3)C2)no1<mask_1:5>	4	14	5	CCN(	5	Cc1nc([C@@H]2CCCN(CC(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	CCN(C
<\|startoftext\|><L>Cc1nc([<mask_1:1>]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:1>	4	7	1	C@@H	1	Cc1nc([C]2CCCN(C(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	C
<\|startoftext\|><L>Cc1nc(<mask_1:3>[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:3>	0	6	3		3	Cc1nc(COC[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	COC
<\|startoftext\|><L>Cc1nc([C@@H]2CCCN(C(=O)C3=<mask_1:3>CCC3)C2)no1<mask_1:3>	2	26	3	CO	3	Cc1nc([C@@H]2CCCN(C(=O)C3=CCCCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	CCC
<\|startoftext\|><L>Cc1nc([C@@H]2CCCN(C(=O)C3=CO<mask_1:5>CC3)C2)no1<mask_1:5>	1	28	5	C	5	Cc1nc([C@@H]2CCCN(C(=O)C3=COC(=O)CC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	C(=O)
<\|startoftext\|><L>Cc1nc([C@@H]2CCCN(C(=O)C<mask_1:2>=COCCC3)C2)no1<mask_1:2>	1	24	2	3	2	Cc1nc([C@@H]2CCCN(C(=O)CC3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	C3
<\|startoftext\|><L>Cc1<mask_1:4>[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:4>	3	3	4	nc(	4	Cc1nc(C[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1	nc(C
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccc<mask_1:4>c23)C1<mask_1:4>	1	39	4	c	4	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3cccc(F)c23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	c(F)
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N<mask_1:6>2cccc3ccccc23)C1<mask_1:6>	3	27	6	(Cc	6	O=C(Cn1cccn1)N[C@H]1CC(=O)N(CCCOc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	(CCCOc
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1C<mask_1:1>O)N(Cc2cccc3ccccc23)C1<mask_1:1>	3	21	1	C(=	1	O=C(Cn1cccn1)N[C@H]1C(O)N(Cc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	(
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3<mask_1:5>cccc23)C1<mask_1:5>	1	36	5	c	5	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3c(Cl)cccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	c(Cl)
<\|startoftext\|><L>O=C(Cn1cccn1)<mask_1:6>@H]1CC(=O)N(Cc2cccc3ccccc23)C1<mask_1:6>	3	13	6	N[C	6	O=C(Cn1cccn1)NCC[C@@H]1CC(=O)N(Cc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	NCC[C@
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC<mask_1:1>O)N(Cc2cccc3ccccc23)C1<mask_1:1>	2	22	1	(=	1	O=C(Cn1cccn1)N[C@H]1CC(O)N(Cc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	(
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1<mask_1:1>CC(=O)N(Cc2cccc3ccccc23)C1<mask_1:1>	0	20	1		1	O=C(Cn1cccn1)N[C@H]1CCC(=O)N(Cc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	C
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N<mask_1:6>cccc3ccccc23)C1<mask_1:6>	4	27	6	(Cc2	6	O=C(Cn1cccn1)N[C@H]1CC(=O)N(CCOc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	(CCOc2
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)<mask_1:5>ccc3ccccc23)C1<mask_1:5>	6	26	5	N(Cc2c	5	O=C(Cn1cccn1)N[C@H]1CC(=O)N(c2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	N(c2c
<\|startoftext\|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N<mask_1:4>Cc2cccc3ccccc23)C1<mask_1:4>	1	27	4	(	4	O=C(Cn1cccn1)N[C@H]1CC(=O)N(CCOCc2cccc3ccccc23)C1	O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1	(CCO
<\|startoftext\|><L>CO<mask_1:2>c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:2>	4	2	2	CCn1	2	COn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	n1
<\|startoftext\|><L>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(<mask_1:8>c1ccc(F)cc1)c(=O)n2C<mask_1:8>	6	31	8	=O)n(C	8	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(CCCc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	=O)n(CCC
<\|startoftext\|><L>COCCn1c(-n2nc(C)c(<mask_1:8>nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:8>	6	18	8	C)c2C)	8	COCCn1c(-n2nc(C)c(C)c2C#N)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	C)c2C#N)
<\|startoftext\|><L>COCCn1c(-n2nc(C)c<mask_1:8>)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:8>	6	17	8	(C)c2C	8	COCCn1c(-n2nc(C)c(C)c2C#N)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	(C)c2C#N
<\|startoftext\|><L>CO<mask_1:8>CCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:8>	0	2	8		8	COCCNC(=O)CCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	CCNC(=O)
<\|startoftext\|><L>COCCn1c(-n2nc(C)<mask_1:5>C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:5>	6	16	5	c(C)c2	5	COCCn1c(-n2nc(C)cc2COC)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	cc2CO
<\|startoftext\|><L>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O<mask_1:7>1ccc(F)cc1)c(=O)n2C<mask_1:7>	5	33	7	)n(Cc	7	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(CCCc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	)n(CCCc
<\|startoftext\|><L>COCC<mask_1:3>c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:3>	2	4	3	n1	3	COCCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	Cn1
<\|startoftext\|><L>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O<mask_1:6>C<mask_1:6>	3	53	6	)n2	6	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2CCOC	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	)n2CCO
<\|startoftext\|><L><mask_1:3>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:3>	0	0	3		3	COCCOCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C	COC
<\|startoftext\|><L>C[C@@H](NC(=O)<mask_1:3>(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:3>	5	14	3	CC(C)	3	C[C@@H](NC(=O)COC(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	COC
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O<mask_1:5>ccccn2)CC1<mask_1:5>	6	34	5	)CCCc2	5	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	)CCc2
<\|startoftext\|><L>C[C@@H](NC(=O)<mask_1:1>(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:1>	2	14	1	CC	1	C[C@@H](NC(=O)C(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	C
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2cc<mask_1:6>n2)CC1<mask_1:6>	2	42	6	cc	6	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccc(Cl)cn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	c(Cl)c
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CC<mask_1:5>C(=O)CCCc2ccccn2)CC1<mask_1:5>	2	28	5	N(	5	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(CCNC(=O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	N(CCN
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F)<mask_1:4>(C(=O)CCCc2ccccn2)CC1<mask_1:4>	5	24	4	C1CCN	4	C[C@@H](NC(=O)CC(C)(F)F)C1CN(C(=O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	C1CN
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CC<mask_1:6>cccn2)CC1<mask_1:6>	4	37	6	Cc2c	6	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCc2c(O)cccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	c2c(O)
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F)C1C<mask_1:4>O)CCCc2ccccn2)CC1<mask_1:4>	6	27	4	CN(C(=	4	C[C@@H](NC(=O)CC(C)(F)F)C1CN(C(O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	N(C(
<\|startoftext\|><L>C[C@@H](<mask_1:6>O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:6>	4	8	6	NC(=	6	C[C@@H](CCNC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	CCNC(=
<\|startoftext\|><L>C[C@@H](NC(=O)CC(C)(F)F<mask_1:7>)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:7>	0	23	7		7	C[C@@H](NC(=O)CC(C)(F)F)CNC(=O)C1CCN(C(=O)CCCc2ccccn2)CC1	C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1	)CNC(=O
<\|startoftext\|><L>O=C(NC[C@H]<mask_1:4>CCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:4>	2	11	4	1C	4	O=C(NC[C@H]1CN=CCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	1CN=
<\|startoftext\|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc<mask_1:6>O)[O-]<mask_1:6>	7	42	6	1[N+](=	7	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	1[N+](=
<\|startoftext\|><L>O=C(NC[C@H]1CCCC<mask_1:4>)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:4>	8	16	4	[C@@H]1O	4	O=C(NC[C@H]1CCCCN1CO)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	N1CO
<\|startoftext\|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+]<mask_1:5>(=O)[O-]<mask_1:5>	0	47	5		5	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)C(=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	(=O)C
<\|startoftext\|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)<mask_1:6>N+](=O)[O-]<mask_1:6>	4	40	6	cc1[	6	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1C/[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	cc1C/[
<\|startoftext\|><L>O=<mask_1:8>@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:8>	6	2	8	C(NC[C	8	O=C(NCC[C@@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	C(NCC[C@
<\|startoftext\|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F<mask_1:7>)F)cc1[N+](=O)[O-]<mask_1:7>	0	37	7		7	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	)C(F)(F
<\|startoftext\|><L>O=C(<mask_1:3>1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:3>	7	4	3	NC[C@H]	3	O=C(NCC1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	NCC
<\|startoftext\|><L>O=C(N<mask_1:8>C[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:8>	0	5	8		8	O=C(NCC(=O)NCC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	CC(=O)NC
<\|startoftext\|><L>O=C(NC[C@H]1<mask_1:5>CC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:5>	2	12	5	CC	5	O=C(NC[C@H]1CC=CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]	CC=CC
<\|startoftext\|><L>O=C(O)c1nnn2c1C<mask_1:4>O[C@H](c1ccc(Cl)cc1)C2<mask_1:4>	0	15	4		4	O=C(O)c1nnn2c1C(=O)O[C@H](c1ccc(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	(=O)
<\|startoftext\|><L>O=C(O<mask_1:5>c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:5>	1	5	5	)	5	O=C(O)CCCOc1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	)CCCO
<\|startoftext\|><L>O=C(O)c1<mask_1:5>nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:5>	0	8	5		5	O=C(O)c1cc(O)nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	cc(O)
<\|startoftext\|><L>O=C(O)<mask_1:2>1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:2>	1	6	2	c	2	O=C(O)Cc1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	Cc
<\|startoftext\|><L>O=C(O)c1nnn2c1CO[C@<mask_1:1>H](c1ccc(Cl)cc1)C2<mask_1:1>	0	19	1		1	O=C(O)c1nnn2c1CO[C@@H](c1ccc(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	@
<\|startoftext\|><L>O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1<mask_1:3>C2<mask_1:3>	1	34	3	)	3	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C=C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	)C=
<\|startoftext\|><L><mask_1:5>O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:5>	4	0	5	O=C(	5	COC(=O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	COC(=
<\|startoftext\|><L>O=C(O)c1nnn2c1CO[C@H](<mask_1:2>(Cl)cc1)C2<mask_1:2>	5	22	2	c1ccc	2	O=C(O)c1nnn2c1CO[C@H](c1(Cl)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	c1
<\|startoftext\|><L>O=C(O)c1nnn2c1CO[C@H](c1ccc(<mask_1:4>cc1)C2<mask_1:4>	3	28	4	Cl)	4	O=C(O)c1nnn2c1CO[C@H](c1ccc(C=O)cc1)C2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	C=O)
<\|startoftext\|><L>O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1<mask_1:2>C2<mask_1:2>	1	34	2	)	2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)CC2	O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2	)C
<\|startoftext\|><L>Cc1cc(NC<mask_1:7>(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:7>	0	8	7		7	Cc1cc(NC(=O)COC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	(=O)COC
<\|startoftext\|><L>Cc1<mask_1:8>O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:8>	7	3	8	cc(NC(=	8	Cc1cc(CNC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	cc(CNC(=
<\|startoftext\|><L>C<mask_1:5>C(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:5>	6	1	5	c1cc(N	5	Cc1cc(C(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	c1cc(
<\|startoftext\|><L>Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(<mask_1:6>)F)cc3)c2=O)no1<mask_1:6>	1	38	6	F	6	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)OC(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	F)OC(F
<\|startoftext\|><L>Cc1cc(N<mask_1:8>2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:8>	7	7	8	C(=O)Cn	8	Cc1cc(NC(=O)CCn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	C(=O)CCn
<\|startoftext\|><L>Cc1cc(NC(=O)Cn2cnc3c(nn<mask_1:5>(OC(F)(F)F)cc3)c2=O)no1<mask_1:5>	8	23	5	n3-c3ccc	5	Cc1cc(NC(=O)Cn2cnc3c(nnn3c3c(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	n3c3c
<\|startoftext\|><L><mask_1:4>Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:4>	0	0	4		4	CCCCCc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	CCCC
<\|startoftext\|><L>Cc1cc(NC(=O)Cn2cnc3c(nnn3-<mask_1:8>C(F)(F)F)cc3)c2=O)no1<mask_1:8>	7	26	8	c3ccc(O	8	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OCC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	c3ccc(OC
<\|startoftext\|><L><mask_1:6>(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:6>	5	0	6	Cc1cc	6	CCc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	CCc1cc
<\|startoftext\|><L>Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3c<mask_1:3>C(F)(F)F)cc3)c2=O)no1<mask_1:3>	4	29	3	cc(O	3	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(C(F)(F)F)cc3)c2=O)no1	Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1	cc(
<\|startoftext\|><L>Cc1n[nH]<mask_1:5>(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:5>	7	8	5	c(C)c1C	5	Cc1n[nH]cc1NC(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	cc1NC
<\|startoftext\|><L>Cc<mask_1:6>)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:6>	9	2	6	1n[nH]c(C	6	Cc1noc(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	1noc(C
<\|startoftext\|><L>Cc1n[nH]c(C<mask_1:5>O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:5>	6	11	5	)c1C(=	5	Cc1n[nH]c(C)c1C(O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	)c1C(
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H<mask_1:9>cc(C(C)C)cc1<mask_1:9>	5	47	9	]1c1c	9	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1c(Cl)cc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	]1c1c(Cl)
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=<mask_1:8>C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:8>	9	17	8	O)C1=C(O)	9	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	O)C1=C(O)
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=O)C1<mask_1:6>(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:6>	2	21	6	=C	6	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	=C(O)C
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)<mask_1:1>[C@H]1c1ccc(C(C)C)cc1<mask_1:1>	0	43	1		1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	C
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(<mask_1:9>1<mask_1:9>	8	55	9	C(C)C)cc	9	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)(C)C)1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	C(C)(C)C)
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=O<mask_1:3>(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:3>	5	18	3	)C1=C	3	Cc1n[nH]c(C)c1C(=O)C1(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	)C1
<\|startoftext\|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(<mask_1:2>1<mask_1:2>	8	55	2	C(C)C)cc	2	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C)1	Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1	C)
<\|startoftext\|><L>C[C@@H](CCc1cccn1C<mask_1:4>Nc1cnn(C)c(=O)c1Cl<mask_1:4>	1	18	4	)	4	C[C@@H](CCc1cccn1C)NCCNc1cnn(C)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	)NCC
<\|startoftext\|><L>C[C@@H](CCc1cccn1C)Nc1cnn(C<mask_1:4>(=O)c1Cl<mask_1:4>	2	27	4	)c	4	C[C@@H](CCc1cccn1C)Nc1cnn(CCN)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	CN)c
<\|startoftext\|><L>C[C@@H](CCc1cccn1C)Nc1cnn(C<mask_1:1>)c(=O)c1Cl<mask_1:1>	0	27	1		1	C[C@@H](CCc1cccn1C)Nc1cnn(Cl)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	l
<\|startoftext\|><L>C[C@@H]<mask_1:2>CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:2>	1	7	2	(	2	C[C@@H](CCCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	(C
<\|startoftext\|><L>C[C@@H](CCc1cccn1C)Nc1cnn(<mask_1:5>)c(=O)c1Cl<mask_1:5>	1	26	5	C	5	C[C@@H](CCc1cccn1C)Nc1cnn(C(F)F)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	C(F)F
<\|startoftext\|><L>C[C<mask_1:2>(CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:2>	4	3	2	@@H]	2	C[CH](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	H]
<\|startoftext\|><L>C[C@@H](<mask_1:4>ccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:4>	5	8	4	CCc1c	4	C[C@@H](Cc1nccn1C)Nc1cnn(C)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	Cc1n
<\|startoftext\|><L>C[C@@H](CCc1cccn1C)Nc1c<mask_1:2>c(=O)c1Cl<mask_1:2>	5	23	2	nn(C)	2	C[C@@H](CCc1cccn1C)Nc1ccoc(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	co
<\|startoftext\|><L>C[C@<mask_1:1>(CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:1>	3	4	1	@H]	1	C[C@](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	]
<\|startoftext\|><L>C[C@@H](<mask_1:1>1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:1>	3	8	1	CCc	1	C[C@@H](c1cccn1C)Nc1cnn(C)c(=O)c1Cl	C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl	c

<|startoftext|><L>COc1ccc(/C<mask_1:1>c2ncnc3[nH]cnc23)c(OC)c1<mask_1:1>

4

10

1

=N/N

1

COc1ccc(/CNc2ncnc3[nH]cnc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

N

<|startoftext|><L>COc1ccc(/C=N<mask_1:5>Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:5>

1

12

5

/

5

COc1ccc(/C=N/NCCCNc2ncnc3[nH]cnc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

/NCCC

<|startoftext|><L>COc1ccc(/C=N/Nc2ncnc3[nH]c<mask_1:5>)c(OC)c1<mask_1:5>

4

26

5

nc23

4

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

nc23

<|startoftext|><L>COc1ccc(/C=N/Nc2ncn<mask_1:4>]cnc23)c(OC)c1<mask_1:4>

5

19

4

c3[nH

5

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

c3[nH

<|startoftext|><L>COc1ccc(/<mask_1:5>N/Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:5>

2

9

5

C=

5

COc1ccc(/C(C)=N/Nc2ncnc3[nH]cnc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

C(C)=

<|startoftext|><L>COc1ccc(<mask_1:4>C=N/Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:4>

1

8

4

/

4

COc1ccc(C=C/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

C=C/

<|startoftext|><L>COc1ccc(/C<mask_1:2>2ncnc3[nH]cnc23)c(OC)c1<mask_1:2>

5

10

2

=N/Nc

2

COc1ccc(/CNc2ncnc3[nH]cnc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

Nc

<|startoftext|><L>COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(<mask_1:3>OC)c1<mask_1:3>

0

33

3

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OCCOC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

OCC

<|startoftext|><L>COc1ccc(<mask_1:5>=N/Nc2ncnc3[nH]cnc23)c(OC)c1<mask_1:5>

2

8

5

/C

5

COc1ccc(/C(C)=N/Nc2ncnc3[nH]cnc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

/C(C)

<|startoftext|><L>COc1ccc(/C=N/Nc2ncnc3[nH]c<mask_1:4>nc23)c(OC)c1<mask_1:4>

0

26

4

COc1ccc(/C=N/Nc2ncnc3[nH]c(Br)nc23)c(OC)c1

COc1ccc(/C=N/Nc2ncnc3[nH]cnc23)c(OC)c1

(Br)

<|startoftext|><L>Cc1nc([C@@H]2<mask_1:3>(C(=O)C3=COCCC3)C2)no1<mask_1:3>

4

13

3

CCCN

3

Cc1nc([C@@H]2CCN(C(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

CCN

<|startoftext|><L>Cc1nc(<mask_1:5>[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:5>

0

6

5

Cc1nc(CN(C)[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

CN(C)

<|startoftext|><L>Cc1nc([C@@H]2CC<mask_1:2>N(C(=O)C3=COCCC3)C2)no1<mask_1:2>

1

15

2

C

2

Cc1nc([C@@H]2CCCCN(C(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

CC

<|startoftext|><L>Cc1nc([C@@H]2C<mask_1:5>C(=O)C3=COCCC3)C2)no1<mask_1:5>

4

14

5

CCN(

5

Cc1nc([C@@H]2CCCN(CC(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

CCN(C

<|startoftext|><L>Cc1nc([<mask_1:1>]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:1>

4

7

1

C@@H

1

Cc1nc([C]2CCCN(C(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

C

<|startoftext|><L>Cc1nc(<mask_1:3>[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:3>

0

6

3

Cc1nc(COC[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

COC

<|startoftext|><L>Cc1nc([C@@H]2CCCN(C(=O)C3=<mask_1:3>CCC3)C2)no1<mask_1:3>

2

26

3

CO

3

Cc1nc([C@@H]2CCCN(C(=O)C3=CCCCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

CCC

<|startoftext|><L>Cc1nc([C@@H]2CCCN(C(=O)C3=CO<mask_1:5>CC3)C2)no1<mask_1:5>

1

28

5

C

5

Cc1nc([C@@H]2CCCN(C(=O)C3=COC(=O)CC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

C(=O)

<|startoftext|><L>Cc1nc([C@@H]2CCCN(C(=O)C<mask_1:2>=COCCC3)C2)no1<mask_1:2>

1

24

2

3

2

Cc1nc([C@@H]2CCCN(C(=O)CC3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

C3

<|startoftext|><L>Cc1<mask_1:4>[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1<mask_1:4>

3

4

nc(

4

Cc1nc(C[C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

Cc1nc([C@@H]2CCCN(C(=O)C3=COCCC3)C2)no1

nc(C

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccc<mask_1:4>c23)C1<mask_1:4>

1

39

4

c

4

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3cccc(F)c23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

c(F)

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N<mask_1:6>2cccc3ccccc23)C1<mask_1:6>

3

27

6

(Cc

6

O=C(Cn1cccn1)N[C@H]1CC(=O)N(CCCOc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

(CCCOc

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1C<mask_1:1>O)N(Cc2cccc3ccccc23)C1<mask_1:1>

3

21

1

C(=

1

O=C(Cn1cccn1)N[C@H]1C(O)N(Cc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

(

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3<mask_1:5>cccc23)C1<mask_1:5>

1

36

5

c

5

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3c(Cl)cccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

c(Cl)

<|startoftext|><L>O=C(Cn1cccn1)<mask_1:6>@H]1CC(=O)N(Cc2cccc3ccccc23)C1<mask_1:6>

3

13

6

N[C

6

O=C(Cn1cccn1)NCC[C@@H]1CC(=O)N(Cc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

NCC[C@

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC<mask_1:1>O)N(Cc2cccc3ccccc23)C1<mask_1:1>

2

22

1

(=

1

O=C(Cn1cccn1)N[C@H]1CC(O)N(Cc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

(

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1<mask_1:1>CC(=O)N(Cc2cccc3ccccc23)C1<mask_1:1>

0

20

1

O=C(Cn1cccn1)N[C@H]1CCC(=O)N(Cc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

C

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N<mask_1:6>cccc3ccccc23)C1<mask_1:6>

4

27

6

(Cc2

6

O=C(Cn1cccn1)N[C@H]1CC(=O)N(CCOc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

(CCOc2

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)<mask_1:5>ccc3ccccc23)C1<mask_1:5>

6

26

5

N(Cc2c

5

O=C(Cn1cccn1)N[C@H]1CC(=O)N(c2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

N(c2c

<|startoftext|><L>O=C(Cn1cccn1)N[C@H]1CC(=O)N<mask_1:4>Cc2cccc3ccccc23)C1<mask_1:4>

1

27

4

(

4

O=C(Cn1cccn1)N[C@H]1CC(=O)N(CCOCc2cccc3ccccc23)C1

O=C(Cn1cccn1)N[C@H]1CC(=O)N(Cc2cccc3ccccc23)C1

(CCO

<|startoftext|><L>CO<mask_1:2>c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:2>

4

2

CCn1

2

COn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

n1

<|startoftext|><L>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(<mask_1:8>c1ccc(F)cc1)c(=O)n2C<mask_1:8>

6

31

8

=O)n(C

8

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(CCCc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

=O)n(CCC

<|startoftext|><L>COCCn1c(-n2nc(C)c(<mask_1:8>nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:8>

6

18

8

C)c2C)

8

COCCn1c(-n2nc(C)c(C)c2C#N)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

C)c2C#N)

<|startoftext|><L>COCCn1c(-n2nc(C)c<mask_1:8>)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:8>

6

17

8

(C)c2C

8

COCCn1c(-n2nc(C)c(C)c2C#N)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

(C)c2C#N

<|startoftext|><L>CO<mask_1:8>CCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:8>

0

2

8

COCCNC(=O)CCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

CCNC(=O)

<|startoftext|><L>COCCn1c(-n2nc(C)<mask_1:5>C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:5>

6

16

5

c(C)c2

5

COCCn1c(-n2nc(C)cc2COC)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

cc2CO

<|startoftext|><L>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O<mask_1:7>1ccc(F)cc1)c(=O)n2C<mask_1:7>

5

33

7

)n(Cc

7

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(CCCc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

)n(CCCc

<|startoftext|><L>COCC<mask_1:3>c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:3>

2

4

3

n1

3

COCCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

Cn1

<|startoftext|><L>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O<mask_1:6>C<mask_1:6>

3

53

6

)n2

6

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2CCOC

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

)n2CCO

<|startoftext|><L><mask_1:3>COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C<mask_1:3>

0

3

COCCOCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(Cc1ccc(F)cc1)c(=O)n2C

COC

<|startoftext|><L>C[C@@H](NC(=O)<mask_1:3>(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:3>

5

14

3

CC(C)

3

C[C@@H](NC(=O)COC(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

COC

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O<mask_1:5>ccccn2)CC1<mask_1:5>

6

34

5

)CCCc2

5

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

)CCc2

<|startoftext|><L>C[C@@H](NC(=O)<mask_1:1>(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:1>

2

14

1

CC

1

C[C@@H](NC(=O)C(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

C

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2cc<mask_1:6>n2)CC1<mask_1:6>

2

42

6

cc

6

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccc(Cl)cn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

c(Cl)c

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CC<mask_1:5>C(=O)CCCc2ccccn2)CC1<mask_1:5>

2

28

5

N(

5

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(CCNC(=O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

N(CCN

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F)<mask_1:4>(C(=O)CCCc2ccccn2)CC1<mask_1:4>

5

24

4

C1CCN

4

C[C@@H](NC(=O)CC(C)(F)F)C1CN(C(=O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

C1CN

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CC<mask_1:6>cccn2)CC1<mask_1:6>

4

37

6

Cc2c

6

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCc2c(O)cccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

c2c(O)

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F)C1C<mask_1:4>O)CCCc2ccccn2)CC1<mask_1:4>

6

27

4

CN(C(=

4

C[C@@H](NC(=O)CC(C)(F)F)C1CN(C(O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

N(C(

<|startoftext|><L>C[C@@H](<mask_1:6>O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:6>

4

8

6

NC(=

6

C[C@@H](CCNC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

CCNC(=

<|startoftext|><L>C[C@@H](NC(=O)CC(C)(F)F<mask_1:7>)C1CCN(C(=O)CCCc2ccccn2)CC1<mask_1:7>

0

23

7

C[C@@H](NC(=O)CC(C)(F)F)CNC(=O)C1CCN(C(=O)CCCc2ccccn2)CC1

C[C@@H](NC(=O)CC(C)(F)F)C1CCN(C(=O)CCCc2ccccn2)CC1

)CNC(=O

<|startoftext|><L>O=C(NC[C@H]<mask_1:4>CCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:4>

2

11

4

1C

4

O=C(NC[C@H]1CN=CCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

1CN=

<|startoftext|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc<mask_1:6>O)[O-]<mask_1:6>

7

42

6

1[N+](=

7

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

1[N+](=

<|startoftext|><L>O=C(NC[C@H]1CCCC<mask_1:4>)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:4>

8

16

4

[C@@H]1O

4

O=C(NC[C@H]1CCCCN1CO)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

N1CO

<|startoftext|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+]<mask_1:5>(=O)[O-]<mask_1:5>

0

47

5

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)C(=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

(=O)C

<|startoftext|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)<mask_1:6>N+](=O)[O-]<mask_1:6>

4

40

6

cc1[

6

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1C/[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

cc1C/[

<|startoftext|><L>O=<mask_1:8>@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:8>

6

2

8

C(NC[C

8

O=C(NCC[C@@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

C(NCC[C@

<|startoftext|><L>O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F<mask_1:7>)F)cc1[N+](=O)[O-]<mask_1:7>

0

37

7

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

)C(F)(F

<|startoftext|><L>O=C(<mask_1:3>1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:3>

7

4

3

NC[C@H]

3

O=C(NCC1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

NCC

<|startoftext|><L>O=C(N<mask_1:8>C[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:8>

0

5

8

O=C(NCC(=O)NCC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

CC(=O)NC

<|startoftext|><L>O=C(NC[C@H]1<mask_1:5>CC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]<mask_1:5>

2

12

5

CC

5

O=C(NC[C@H]1CC=CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

O=C(NC[C@H]1CCCC[C@@H]1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

CC=CC

<|startoftext|><L>O=C(O)c1nnn2c1C<mask_1:4>O[C@H](c1ccc(Cl)cc1)C2<mask_1:4>

0

15

4

O=C(O)c1nnn2c1C(=O)O[C@H](c1ccc(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

(=O)

<|startoftext|><L>O=C(O<mask_1:5>c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:5>

1

5

)

5

O=C(O)CCCOc1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

)CCCO

<|startoftext|><L>O=C(O)c1<mask_1:5>nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:5>

0

8

5

O=C(O)c1cc(O)nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

cc(O)

<|startoftext|><L>O=C(O)<mask_1:2>1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:2>

1

6

2

c

2

O=C(O)Cc1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

Cc

<|startoftext|><L>O=C(O)c1nnn2c1CO[C@<mask_1:1>H](c1ccc(Cl)cc1)C2<mask_1:1>

0

19

1

O=C(O)c1nnn2c1CO[C@@H](c1ccc(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

@

<|startoftext|><L>O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1<mask_1:3>C2<mask_1:3>

1

34

3

)

3

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C=C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

)C=

<|startoftext|><L><mask_1:5>O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2<mask_1:5>

4

0

5

O=C(

5

COC(=O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

COC(=

<|startoftext|><L>O=C(O)c1nnn2c1CO[C@H](<mask_1:2>(Cl)cc1)C2<mask_1:2>

5

22

2

c1ccc

2

O=C(O)c1nnn2c1CO[C@H](c1(Cl)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

c1

<|startoftext|><L>O=C(O)c1nnn2c1CO[C@H](c1ccc(<mask_1:4>cc1)C2<mask_1:4>

3

28

4

Cl)

4

O=C(O)c1nnn2c1CO[C@H](c1ccc(C=O)cc1)C2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

C=O)

<|startoftext|><L>O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1<mask_1:2>C2<mask_1:2>

1

34

2

)

2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)CC2

O=C(O)c1nnn2c1CO[C@H](c1ccc(Cl)cc1)C2

)C

<|startoftext|><L>Cc1cc(NC<mask_1:7>(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:7>

0

8

7

Cc1cc(NC(=O)COC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

(=O)COC

<|startoftext|><L>Cc1<mask_1:8>O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:8>

7

3

8

cc(NC(=

8

Cc1cc(CNC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

cc(CNC(=

<|startoftext|><L>C<mask_1:5>C(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:5>

6

1

5

c1cc(N

5

Cc1cc(C(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

c1cc(

<|startoftext|><L>Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(<mask_1:6>)F)cc3)c2=O)no1<mask_1:6>

1

38

6

F

6

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)OC(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

F)OC(F

<|startoftext|><L>Cc1cc(N<mask_1:8>2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:8>

7

8

C(=O)Cn

8

Cc1cc(NC(=O)CCn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

C(=O)CCn

<|startoftext|><L>Cc1cc(NC(=O)Cn2cnc3c(nn<mask_1:5>(OC(F)(F)F)cc3)c2=O)no1<mask_1:5>

8

23

5

n3-c3ccc

5

Cc1cc(NC(=O)Cn2cnc3c(nnn3c3c(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

n3c3c

<|startoftext|><L><mask_1:4>Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:4>

0

4

CCCCCc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

CCCC

<|startoftext|><L>Cc1cc(NC(=O)Cn2cnc3c(nnn3-<mask_1:8>C(F)(F)F)cc3)c2=O)no1<mask_1:8>

7

26

8

c3ccc(O

8

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OCC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

c3ccc(OC

<|startoftext|><L><mask_1:6>(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1<mask_1:6>

5

0

6

Cc1cc

6

CCc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

CCc1cc

<|startoftext|><L>Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3c<mask_1:3>C(F)(F)F)cc3)c2=O)no1<mask_1:3>

4

29

3

cc(O

3

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(C(F)(F)F)cc3)c2=O)no1

Cc1cc(NC(=O)Cn2cnc3c(nnn3-c3ccc(OC(F)(F)F)cc3)c2=O)no1

cc(

<|startoftext|><L>Cc1n[nH]<mask_1:5>(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:5>

7

8

5

c(C)c1C

5

Cc1n[nH]cc1NC(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

cc1NC

<|startoftext|><L>Cc<mask_1:6>)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:6>

9

2

6

1n[nH]c(C

6

Cc1noc(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

1noc(C

<|startoftext|><L>Cc1n[nH]c(C<mask_1:5>O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:5>

6

11

5

)c1C(=

5

Cc1n[nH]c(C)c1C(O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

)c1C(

<|startoftext|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H<mask_1:9>cc(C(C)C)cc1<mask_1:9>

5

47

9

]1c1c

9

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1c(Cl)cc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

]1c1c(Cl)

<|startoftext|><L>Cc1n[nH]c(C)c1C(=<mask_1:8>C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:8>

9

17

8

O)C1=C(O)

9

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

O)C1=C(O)

<|startoftext|><L>Cc1n[nH]c(C)c1C(=O)C1<mask_1:6>(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:6>

2

21

6

=C

6

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

=C(O)C

<|startoftext|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)<mask_1:1>[C@H]1c1ccc(C(C)C)cc1<mask_1:1>

0

43

1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C[C@H]1c1ccc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

C

<|startoftext|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(<mask_1:9>1<mask_1:9>

8

55

9

C(C)C)cc

9

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)(C)C)1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

C(C)(C)C)

<|startoftext|><L>Cc1n[nH]c(C)c1C(=O<mask_1:3>(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1<mask_1:3>

5

18

3

)C1=C

3

Cc1n[nH]c(C)c1C(=O)C1(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

)C1

<|startoftext|><L>Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(<mask_1:2>1<mask_1:2>

8

55

2

C(C)C)cc

2

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C)1

Cc1n[nH]c(C)c1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)[C@H]1c1ccc(C(C)C)cc1

C)

<|startoftext|><L>C[C@@H](CCc1cccn1C<mask_1:4>Nc1cnn(C)c(=O)c1Cl<mask_1:4>

1

18

4

)

4

C[C@@H](CCc1cccn1C)NCCNc1cnn(C)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

)NCC

<|startoftext|><L>C[C@@H](CCc1cccn1C)Nc1cnn(C<mask_1:4>(=O)c1Cl<mask_1:4>

2

27

4

)c

4

C[C@@H](CCc1cccn1C)Nc1cnn(CCN)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

CN)c

<|startoftext|><L>C[C@@H](CCc1cccn1C)Nc1cnn(C<mask_1:1>)c(=O)c1Cl<mask_1:1>

0

27

1

C[C@@H](CCc1cccn1C)Nc1cnn(Cl)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

l

<|startoftext|><L>C[C@@H]<mask_1:2>CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:2>

1

7

2

(

2

C[C@@H](CCCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

(C

<|startoftext|><L>C[C@@H](CCc1cccn1C)Nc1cnn(<mask_1:5>)c(=O)c1Cl<mask_1:5>

1

26

5

C

5

C[C@@H](CCc1cccn1C)Nc1cnn(C(F)F)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

C(F)F

<|startoftext|><L>C[C<mask_1:2>(CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:2>

4

3

2

@@H]

2

C[CH](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

H]

<|startoftext|><L>C[C@@H](<mask_1:4>ccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:4>

5

8

4

CCc1c

4

C[C@@H](Cc1nccn1C)Nc1cnn(C)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

Cc1n

<|startoftext|><L>C[C@@H](CCc1cccn1C)Nc1c<mask_1:2>c(=O)c1Cl<mask_1:2>

5

23

2

nn(C)

2

C[C@@H](CCc1cccn1C)Nc1ccoc(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

co

<|startoftext|><L>C[C@<mask_1:1>(CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:1>

3

4

1

@H]

1

C[C@](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

]

<|startoftext|><L>C[C@@H](<mask_1:1>1cccn1C)Nc1cnn(C)c(=O)c1Cl<mask_1:1>

3

8

1

CCc

1

C[C@@H](c1cccn1C)Nc1cnn(C)c(=O)c1Cl

C[C@@H](CCc1cccn1C)Nc1cnn(C)c(=O)c1Cl

c