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stringlengths 49
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| first_mask_count
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| first_mask_gen_count
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int64 0
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stringlengths 12
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<|startoftext|><L>CC(=O)C1=C(O)<mask_1:2>(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:2> | 1 | 13 | 2 | C | 2 | CC(=O)C1=C(O)NC(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | NC |
<|startoftext|><L>C<mask_1:6>=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:6> | 2 | 1 | 6 | C( | 6 | COCCOC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | OCCOC( |
<|startoftext|><L>CC(=O)C1=<mask_1:3>(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:3> | 1 | 9 | 3 | C | 3 | CC(=O)C1=C=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | C=C |
<|startoftext|><L><mask_1:7>(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:7> | 2 | 0 | 7 | CC | 6 | C=CCOC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | C=CCOC |
<|startoftext|><L>CC(=O)C1=C(O)<mask_1:5>C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:5> | 0 | 13 | 5 | 5 | CC(=O)C1=C(O)C(=O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | C(=O) |
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<|startoftext|><L>CC(=O)C<mask_1:7>C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:7> | 6 | 7 | 7 | 1=C(O) | 7 | CC(=O)C1=C(O)CC(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | 1=C(O)C |
<|startoftext|><L>CC(=O)C1=C(O)C(=O<mask_1:6>2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:6> | 4 | 17 | 6 | )N(c | 6 | CC(=O)C1=C(O)C(=O)N(CCc2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | )N(CCc |
<|startoftext|><L>CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1cccc<mask_1:4>F<mask_1:4> | 2 | 45 | 4 | c1 | 4 | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1OCF | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | c1OC |
<|startoftext|><L>CC(=O)C1=C(O)C(=O)N(c2ccc(C)<mask_1:6>c2)[C@@H]1c1ccccc1F<mask_1:6> | 1 | 28 | 6 | c | 6 | CC(=O)C1=C(O)C(=O)N(c2ccc(C)c(C#N)c2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | c(C#N) |
<|startoftext|><L>CC(=O)C<mask_1:4>(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F<mask_1:4> | 7 | 7 | 4 | 1=C(O)C | 4 | CC(=O)C1=CC(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)[C@@H]1c1ccccc1F | 1=CC |
<|startoftext|><L>COc1ccccc1N1<mask_1:5>@@H](NC(=O)c2cn[nH]c2)CC1=O<mask_1:5> | 3 | 12 | 5 | C[C | 5 | COc1ccccc1N1CCC[C@@H](NC(=O)c2cn[nH]c2)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | CCC[C |
<|startoftext|><L>COc1ccccc1N1C[C@<mask_1:5>H](NC(=O)c2cn[nH]c2)CC1=O<mask_1:5> | 1 | 16 | 5 | @ | 5 | COc1ccccc1N1C[C@H][C@H](NC(=O)c2cn[nH]c2)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | H][C@ |
<|startoftext|><L>COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]<mask_1:6>CC1=O<mask_1:6> | 3 | 34 | 6 | c2) | 6 | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2Cl)CCC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | c2Cl)C |
<|startoftext|><L>COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]<mask_1:4>)CC1=O<mask_1:4> | 2 | 34 | 4 | c2 | 4 | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2Cl)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | c2Cl |
<|startoftext|><L>COc1ccccc1N1C[C@@H](N<mask_1:5>(=O)c2cn[nH]c2)CC1=O<mask_1:5> | 1 | 21 | 5 | C | 5 | COc1ccccc1N1C[C@@H](NS(=O)(=O)c2cn[nH]c2)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | S(=O) |
<|startoftext|><L>COc1ccccc1N1C[C@@H](NC<mask_1:6>(=O)c2cn[nH]c2)CC1=O<mask_1:6> | 0 | 22 | 6 | 6 | COc1ccccc1N1C[C@@H](NC(=O)NC(=O)c2cn[nH]c2)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | (=O)NC |
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<|startoftext|><L>COc1ccccc1N1C[<mask_1:1>@H](NC(=O)c2cn[nH]c2)CC1=O<mask_1:1> | 2 | 14 | 1 | C@ | 1 | COc1ccccc1N1C[C@H](NC(=O)c2cn[nH]c2)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | C |
<|startoftext|><L>COc1ccccc1N1C[C@@<mask_1:3>C(=O)c2cn[nH]c2)CC1=O<mask_1:3> | 4 | 17 | 3 | H](N | 3 | COc1ccccc1N1C[C@@H](C(=O)c2cn[nH]c2)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | H]( |
<|startoftext|><L>COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c<mask_1:4>)CC1=O<mask_1:4> | 1 | 35 | 4 | 2 | 4 | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2C#N)CC1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | 2C#N |
<|startoftext|><L>COc1ccccc1N1C[C@@H](NC(=O)c2cn[n<mask_1:5>C1=O<mask_1:5> | 6 | 32 | 5 | H]c2)C | 5 | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]n2)C1=O | COc1ccccc1N1C[C@@H](NC(=O)c2cn[nH]c2)CC1=O | H]n2) |
<|startoftext|><L>CO[C@H]1CCCN(c2ccc(<mask_1:4>(=O)CC(C)C)cc2)C1<mask_1:4> | 2 | 19 | 4 | NC | 4 | CO[C@H]1CCCN(c2ccc(CCNC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CCNC |
<|startoftext|><L>CO[C@H]1CCCN(<mask_1:4>ccc(NC(=O)CC(C)C)cc2)C1<mask_1:4> | 2 | 13 | 4 | c2 | 4 | CO[C@H]1CCCN(CCc2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CCc2 |
<|startoftext|><L>CO[C@H]1CCC<mask_1:3>(c2ccc(NC(=O)CC(C)C)cc2)C1<mask_1:3> | 1 | 11 | 3 | N | 3 | CO[C@H]1CCCCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CCN |
<|startoftext|><L>CO[<mask_1:2>1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1<mask_1:2> | 4 | 3 | 2 | C@H] | 2 | CO[C]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | C] |
<|startoftext|><L>CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)c<mask_1:3>1<mask_1:3> | 4 | 33 | 3 | c2)C | 3 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | c2) |
<|startoftext|><L>CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C<mask_1:5>c2)C1<mask_1:5> | 2 | 31 | 5 | )c | 5 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)c(C)c2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | )c(C) |
<|startoftext|><L>CO[C@H]1<mask_1:1>N(c2ccc(NC(=O)CC(C)C)cc2)C1<mask_1:1> | 3 | 8 | 1 | CCC | 1 | CO[C@H]1CN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | C |
<|startoftext|><L>CO[<mask_1:5>C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1<mask_1:5> | 0 | 3 | 5 | 5 | CO[C@H][C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | C@H][ |
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<|startoftext|><L>CO[C@H]<mask_1:2>N(c2ccc(NC(=O)CC(C)C)cc2)C1<mask_1:2> | 4 | 7 | 2 | 1CCC | 2 | CO[C@H]1CN(c2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | 1C |
<|startoftext|><L>CO[C@H]1CCCN<mask_1:5>c2ccc(NC(=O)CC(C)C)cc2)C1<mask_1:5> | 1 | 12 | 5 | ( | 5 | CO[C@H]1CCCN(CCCNc2ccc(NC(=O)CC(C)C)cc2)C1 | CO[C@H]1CCCN(c2ccc(NC(=O)CC(C)C)cc2)C1 | (CCCN |
<|startoftext|><L>Cc1ccc(C(=O)C(F)(F)<mask_1:1>C(F)(F)F)c(Cl)c1<mask_1:1> | 0 | 19 | 1 | 1 | Cc1ccc(C(=O)C(F)(F)OC(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | O |
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<|startoftext|><L>Cc1ccc(C<mask_1:2>(F)(F)C(F)(F)F)c(Cl)c1<mask_1:2> | 5 | 8 | 2 | (=O)C | 2 | Cc1ccc(COC(F)(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | OC |
<|startoftext|><L>Cc1ccc(C<mask_1:3>(F)(F)C(F)(F)F)c(Cl)c1<mask_1:3> | 5 | 8 | 3 | (=O)C | 3 | Cc1ccc(COCC(F)(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | OCC |
<|startoftext|><L>Cc1ccc(C(=O)<mask_1:5>(F)C(F)(F)F)c(Cl)c1<mask_1:5> | 4 | 12 | 5 | C(F) | 5 | Cc1ccc(C(=O)OC(F)(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | OC(F) |
<|startoftext|><L>Cc1ccc(C(=O)C(F)(F)C(<mask_1:1>F)(F)F)c(Cl)c1<mask_1:1> | 0 | 21 | 1 | 1 | Cc1ccc(C(=O)C(F)(F)C(CF)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | C |
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<|startoftext|><L>Cc1ccc(C(<mask_1:1>F)(F)C(F)(F)F)c(Cl)c1<mask_1:1> | 5 | 9 | 1 | =O)C( | 1 | Cc1ccc(C(CF)(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | C |
<|startoftext|><L>Cc1ccc(C<mask_1:3>(F)(F)C(F)(F)F)c(Cl)c1<mask_1:3> | 5 | 8 | 3 | (=O)C | 3 | Cc1ccc(CSCC(F)(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | SCC |
<|startoftext|><L>Cc1ccc(C(=O)C(F)(F)C<mask_1:5>(F)(F)F)c(Cl)c1<mask_1:5> | 0 | 20 | 5 | 5 | Cc1ccc(C(=O)C(F)(F)C(=O)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | (=O)C |
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<|startoftext|><L>Cc1ccc(C<mask_1:3>(=O)C(F)(F)C(F)(F)F)c(Cl)c1<mask_1:3> | 0 | 8 | 3 | 3 | Cc1ccc(COCC(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | OCC |
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<|startoftext|><L>Cc1ccc(C(=O)<mask_1:3>(F)C(F)(F)F)c(Cl)c1<mask_1:3> | 4 | 12 | 3 | C(F) | 3 | Cc1ccc(C(=O)C=C(F)C(F)(F)F)c(Cl)c1 | Cc1ccc(C(=O)C(F)(F)C(F)(F)F)c(Cl)c1 | C=C |
<|startoftext|><L>CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3<mask_1:6>(C)c3nc21<mask_1:6> | 4 | 33 | 6 | cccc | 6 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3ccc(C)(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | ccc(C) |
<|startoftext|><L>CCCCn1nc(NC(=O)<mask_1:2>c2cccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:2> | 0 | 15 | 2 | 2 | CCCCn1nc(NC(=O)COc2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CO |
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<|startoftext|><L>CCCCn1nc(NC(=O)c2<mask_1:4>ccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:4> | 1 | 17 | 4 | c | 4 | CCCCn1nc(NC(=O)c2c(C)ccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | c(C) |
<|startoftext|><L>CCCCn1nc<mask_1:4>C(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:4> | 2 | 8 | 4 | (N | 4 | CCCCn1nc(CCNC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | (CCN |
<|startoftext|><L>CCCCn1<mask_1:6>NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:6> | 3 | 6 | 6 | nc( | 6 | CCCCn1c(C)c(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | c(C)c( |
<|startoftext|><L>CCCC<mask_1:3>NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:3> | 5 | 4 | 3 | n1nc( | 3 | CCCC1(CNC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | 1(C |
<|startoftext|><L>CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3c<mask_1:3>)c3nc21<mask_1:3> | 5 | 34 | 3 | ccc(C | 3 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | c(C |
<|startoftext|><L>CCCC<mask_1:2>1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:2> | 1 | 4 | 2 | n | 2 | CCCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | Cn |
<|startoftext|><L>CCCCn1nc(<mask_1:2>=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21<mask_1:2> | 3 | 9 | 2 | NC( | 2 | CCCCn1nc(C(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | C( |
<|startoftext|><L>CCCCn1nc(NC(=O)c2cccc(OC)c2)<mask_1:4>ccc(C)c3nc21<mask_1:4> | 6 | 28 | 4 | c2cc3c | 4 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2c3ccc(C)c3nc21 | CCCCn1nc(NC(=O)c2cccc(OC)c2)c2cc3cccc(C)c3nc21 | c2c3 |
<|startoftext|><L>O=C(NC12CC3CC(CC(C<mask_1:3>C1)C2)c1n[nH]cc1[N+](=O)[O-]<mask_1:3> | 2 | 18 | 3 | 3) | 3 | O=C(NC12CC3CC(CC(C3)CC1)C2)c1n[nH]cc1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | 3)C |
<|startoftext|><L>O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc<mask_1:4>N+](=O)[O-]<mask_1:4> | 2 | 35 | 4 | 1[ | 4 | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1NC[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | 1NC[ |
<|startoftext|><L>O=<mask_1:7>C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-]<mask_1:7> | 0 | 2 | 7 | 7 | O=C(O)CCCC(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | C(O)CCC |
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<|startoftext|><L>O=C(NC12<mask_1:5>C3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-]<mask_1:5> | 1 | 8 | 5 | C | 5 | O=C(NC12CC(O)C3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | CC(O) |
<|startoftext|><L>O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1<mask_1:3>=O)[O-]<mask_1:3> | 5 | 36 | 3 | [N+]( | 3 | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1NC(=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | NC( |
<|startoftext|><L>O=C(NC12CC3CC(CC(C3)C1)C2)c1n[<mask_1:7>1[N+](=O)[O-]<mask_1:7> | 5 | 30 | 7 | nH]cc | 7 | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]c(S)1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | nH]c(S) |
<|startoftext|><L>O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+]<mask_1:6>[O-]<mask_1:6> | 4 | 40 | 6 | (=O) | 6 | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)CC[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | (=O)CC |
<|startoftext|><L>O=C(NC12CC3<mask_1:7>C3)C1)C2)c1n[nH]cc1[N+](=O)[O-]<mask_1:7> | 6 | 11 | 7 | CC(CC( | 7 | O=C(NC12CC3CC(CC(CC3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | CC(CC(C |
<|startoftext|><L>O=C(NC1<mask_1:5>(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-]<mask_1:5> | 6 | 7 | 5 | 2CC3CC | 5 | O=C(NC12CC3C(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | 2CC3C |
<|startoftext|><L>O=C(NC12CC3CC(CC(C<mask_1:5>2)c1n[nH]cc1[N+](=O)[O-]<mask_1:5> | 6 | 18 | 5 | 3)C1)C | 5 | O=C(NC12CC3CC(CC(C3)C1)2)c1n[nH]cc1[N+](=O)[O-] | O=C(NC12CC3CC(CC(C3)C1)C2)c1n[nH]cc1[N+](=O)[O-] | 3)C1) |
<|startoftext|><L>O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c<mask_1:2>Cl)cccc12<mask_1:2> | 1 | 33 | 2 | ( | 2 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(CCl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | (C |
<|startoftext|><L>O=C(NCc1cccs1)c1cc(-c2ccc<mask_1:4>cn2)nc2c(Cl)cccc12<mask_1:4> | 0 | 25 | 4 | 4 | O=C(NCc1cccs1)c1cc(-c2ccc(Cl)cn2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | (Cl) |
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<|startoftext|><L><mask_1:4>Cc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12<mask_1:4> | 5 | 0 | 4 | O=C(N | 4 | O=C(Cc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | O=C( |
<|startoftext|><L>O=C(NCc1ccc<mask_1:6>1)c1cc(-c2ccccn2)nc2c(Cl)cccc12<mask_1:6> | 1 | 11 | 6 | s | 6 | O=C(NCc1cccc(Cl)c1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | c(Cl)c |
<|startoftext|><L>O=C(NCc<mask_1:4>)c1cc(-c2ccccn2)nc2c(Cl)cccc12<mask_1:4> | 6 | 7 | 4 | 1cccs1 | 4 | O=C(NCc1CO1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | 1CO1 |
<|startoftext|><L>O=C<mask_1:6>1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12<mask_1:6> | 4 | 3 | 6 | (NCc | 6 | O=C(NCCCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | (NCCCc |
<|startoftext|><L>O=C(NCc1cccs1)c1cc(-c2ccccn2)n<mask_1:6>c2c(Cl)cccc12<mask_1:6> | 0 | 30 | 6 | 6 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nn1-c1cc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | n1-c1c |
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<|startoftext|><L>O=C(NCc1cccs1)c1cc(-c2cccc<mask_1:6>)nc2c(Cl)cccc12<mask_1:6> | 2 | 26 | 6 | n2 | 6 | O=C(NCc1cccs1)c1cc(-c2cccc(Cl)c2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | (Cl)c2 |
<|startoftext|><L>O=C(NCc1cc<mask_1:5>c1cc(-c2ccccn2)nc2c(Cl)cccc12<mask_1:5> | 4 | 10 | 5 | cs1) | 5 | O=C(NCc1ccccn1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | ccn1) |
<|startoftext|><L>O=C(NCc1cccs1)c1cc(-c2cc<mask_1:4>nc2c(Cl)cccc12<mask_1:4> | 5 | 24 | 4 | ccn2) | 4 | O=C(NCc1cccs1)c1cc(-c2ccco2)nc2c(Cl)cccc12 | O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 | co2) |
<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc<mask_1:2>1OC(C)C<mask_1:2> | 6 | 31 | 2 | (Br)cc | 2 | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccccc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | cc |
<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1O<mask_1:6>C)C<mask_1:6> | 2 | 39 | 6 | C( | 6 | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OCC(C)(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | CC(C)( |
<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(<mask_1:6>=O)c1ccc(Br)cc1OC(C)C<mask_1:6> | 0 | 23 | 6 | 6 | CCOC(=O)CN(Cc1ccccc1)C(=O)CC(=O)c1ccc(Br)cc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | =O)CC( |
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<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(=<mask_1:3>c1ccc(Br)cc1OC(C)C<mask_1:3> | 2 | 24 | 3 | O) | 3 | CCOC(=O)CN(Cc1ccccc1)C(=O)Nc1ccc(Br)cc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | O)N |
<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(=O)c1c<mask_1:5>(Br)cc1OC(C)C<mask_1:5> | 2 | 29 | 5 | cc | 5 | CCOC(=O)CN(Cc1ccccc1)C(=O)c1cc(C)c(Br)cc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | c(C)c |
<|startoftext|><L>CCOC(=O)<mask_1:2>CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C<mask_1:2> | 0 | 8 | 2 | 2 | CCOC(=O)CCCN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | CC |
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<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc<mask_1:1>C(C)C<mask_1:1> | 2 | 37 | 1 | 1O | 1 | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1C(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | 1 |
<|startoftext|><L>CCOC(=O)CN(C<mask_1:5>ccc1)C(=O)c1ccc(Br)cc1OC(C)C<mask_1:5> | 4 | 12 | 5 | c1cc | 5 | CCOC(=O)CN(CCc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | Cc1cc |
<|startoftext|><L>CCOC(=O)CN(Cc1c<mask_1:6>1)C(=O)c1ccc(Br)cc1OC(C)C<mask_1:6> | 4 | 15 | 6 | cccc | 6 | CCOC(=O)CN(Cc1cnn(C)c1)C(=O)c1ccc(Br)cc1OC(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | nn(C)c |
<|startoftext|><L>CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)<mask_1:2>C(C)C<mask_1:2> | 4 | 35 | 2 | cc1O | 2 | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)n1C(C)C | CCOC(=O)CN(Cc1ccccc1)C(=O)c1ccc(Br)cc1OC(C)C | n1 |
<|startoftext|><L>O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C<mask_1:1>1<mask_1:1> | 0 | 47 | 1 | 1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)CC1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | C |
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<|startoftext|><L>O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2ccc<mask_1:5>Cl)c2)C1<mask_1:5> | 2 | 38 | 5 | c( | 5 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2ccc(F)c(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | (F)c( |
<|startoftext|><L>O=S(=O)(c1ccccc1)N1CC[C@<mask_1:2>2(CCCN2Cc2cccc(Cl)c2)C1<mask_1:2> | 1 | 24 | 2 | ] | 2 | O=S(=O)(c1ccccc1)N1CC[C@@]2(CCCN2Cc2cccc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | @] |
<|startoftext|><L>O=S(=O)(c<mask_1:6>ccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1<mask_1:6> | 3 | 9 | 6 | 1cc | 6 | O=S(=O)(c1c(F)cccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | 1c(F)c |
<|startoftext|><L>O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc<mask_1:4>(Cl)c2)C1<mask_1:4> | 5 | 34 | 4 | 2cccc | 4 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2csc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | 2csc |
<|startoftext|><L>O=S(=O)(c1ccccc1)N1CC[C@]2(CC<mask_1:2>c2cccc(Cl)c2)C1<mask_1:2> | 4 | 29 | 2 | CN2C | 2 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCN2c2cccc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | N2 |
<|startoftext|><L>O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc<mask_1:3>C1<mask_1:3> | 7 | 39 | 3 | (Cl)c2) | 3 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2ccccc2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | c2) |
<|startoftext|><L>O=S(=O)(c1ccccc1)N1C<mask_1:1>C[C@]2(CCCN2Cc2cccc(Cl)c2)C1<mask_1:1> | 0 | 20 | 1 | 1 | O=S(=O)(c1ccccc1)N1CCC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | C |
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<|startoftext|><L>O=S(=O)(<mask_1:7>ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1<mask_1:7> | 2 | 8 | 7 | c1 | 7 | O=S(=O)(/C=C/c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | /C=C/c1 |
<|startoftext|><L>O=S(=O)(c1ccc<mask_1:6>)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1<mask_1:6> | 3 | 13 | 6 | cc1 | 6 | O=S(=O)(c1ccc(F)cc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | O=S(=O)(c1ccccc1)N1CC[C@]2(CCCN2Cc2cccc(Cl)c2)C1 | (F)cc1 |
<|startoftext|><L>C[C@H](NC(=S)Nc1ccc(Oc2cc<mask_1:5>)nc1)c1ccccc1<mask_1:5> | 4 | 25 | 5 | ccc2 | 5 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2F)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | ccc2F |
<|startoftext|><L>C[C@H](NC(=S)<mask_1:6>Nc1ccc(Oc2ccccc2)nc1)c1ccccc1<mask_1:6> | 0 | 13 | 6 | 6 | C[C@H](NC(=S)NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | NC(=S) |
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<|startoftext|><L><mask_1:6>C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1<mask_1:6> | 2 | 0 | 6 | C[ | 6 | CC(C)[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | CC(C)[ |
<|startoftext|><L>C[C@H](NC(=S)Nc1ccc(Oc2c<mask_1:5>nc1)c1ccccc1<mask_1:5> | 6 | 24 | 5 | cccc2) | 5 | C[C@H](NC(=S)Nc1ccc(Oc2ccon2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | con2) |
<|startoftext|><L>C[C@H](NC(=S)Nc1c<mask_1:2>c2ccccc2)nc1)c1ccccc1<mask_1:2> | 4 | 17 | 2 | cc(O | 2 | C[C@H](NC(=S)Nc1cn(c2ccccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | n( |
<|startoftext|><L>C[C@H](NC(<mask_1:6>=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1<mask_1:6> | 0 | 10 | 6 | 6 | C[C@H](NC(=O)NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | =O)NC( |
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<|startoftext|><L>C[C@H](NC(=S)Nc1ccc(Oc2ccc<mask_1:6>2)nc1)c1ccccc1<mask_1:6> | 2 | 26 | 6 | cc | 6 | C[C@H](NC(=S)Nc1ccc(Oc2ccc(Cl)cc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | (Cl)cc |
<|startoftext|><L>C[C@H]<mask_1:4>(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1<mask_1:4> | 3 | 6 | 4 | (NC | 4 | C[C@H](CNC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | (CNC |
<|startoftext|><L>C[C@H](NC(=<mask_1:5>cc(Oc2ccccc2)nc1)c1ccccc1<mask_1:5> | 6 | 11 | 5 | S)Nc1c | 5 | C[C@H](NC(=O)c1ccc(Oc2ccccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | O)c1c |
<|startoftext|><L>C[C@H](NC(=S)Nc1ccc(Oc2cc<mask_1:5>ccc2)nc1)c1ccccc1<mask_1:5> | 0 | 25 | 5 | 5 | C[C@H](NC(=S)Nc1ccc(Oc2cc(C#N)ccc2)nc1)c1ccccc1 | C[C@H](NC(=S)Nc1ccc(Oc2ccccc2)nc1)c1ccccc1 | (C#N) |