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<|startoftext|><L>O=C(C[C@@H]1C=CCC1)NCc1cccc(-n<mask_1:7>C(=O)O)n2)c1<mask_1:7> | 5 | 30 | 7 | 2ccc( | 7 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(CCC(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | 2ccc(CC |
<|startoftext|><L>O=C(C[C@@H]1C=CCC1)NCc1cccc(<mask_1:7>2ccc(C(=O)O)n2)c1<mask_1:7> | 2 | 28 | 7 | -n | 7 | O=C(C[C@@H]1C=CCC1)NCc1cccc(NC(=O)n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | NC(=O)n |
<|startoftext|><L>O=C<mask_1:5>[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:5> | 2 | 3 | 5 | (C | 5 | O=C(CCCC[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | (CCCC |
<|startoftext|><L>O=C(C[C@@H]1C=CCC<mask_1:4>NCc1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:4> | 2 | 17 | 4 | 1) | 4 | O=C(C[C@@H]1C=CCC1)NCNCc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | 1)NC |
<|startoftext|><L>O=C(C[C@@H]1C=CCC1)N<mask_1:1>1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:1> | 2 | 20 | 1 | Cc | 1 | O=C(C[C@@H]1C=CCC1)Nc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | c |
<|startoftext|><L>O=C(C[<mask_1:1>@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:1> | 2 | 6 | 1 | C@ | 1 | O=C(C[C@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | C |
<|startoftext|><L>O=C(C[C@@H<mask_1:7>CC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:7> | 5 | 10 | 7 | ]1C=C | 7 | O=C(C[C@@H]1C=CCCCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | ]1C=CCC |
<|startoftext|><L>O=C(C[C@@H]1C<mask_1:3>=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:3> | 0 | 13 | 3 | 3 | O=C(C[C@@H]1CCCC=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | CCC |
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<|startoftext|><L>O=C(C[<mask_1:3>C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1<mask_1:3> | 6 | 6 | 3 | C@@H]1 | 3 | O=C(C[C]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | C]1 |
<|startoftext|><L>O=C(C[C@@H]1C=CCC1)NCc1<mask_1:2>c(-n2ccc(C(=O)O)n2)c1<mask_1:2> | 3 | 23 | 2 | ccc | 2 | O=C(C[C@@H]1C=CCC1)NCc1csc(-n2ccc(C(=O)O)n2)c1 | O=C(C[C@@H]1C=CCC1)NCc1cccc(-n2ccc(C(=O)O)n2)c1 | cs |
<|startoftext|><L>N<mask_1:1>1ccc(-c2nc3ccccc3s2)cc1<mask_1:1> | 3 | 1 | 1 | #Cc | 1 | Nc1ccc(-c2nc3ccccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | c |
<|startoftext|><L>N#Cc1ccc(-c2n<mask_1:4>ccccc3s2)cc1<mask_1:4> | 2 | 13 | 4 | c3 | 4 | N#Cc1ccc(-c2nnc3cccccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | nc3c |
<|startoftext|><L>N#Cc1c<mask_1:4>c(-c2nc3ccccc3s2)cc1<mask_1:4> | 1 | 6 | 4 | c | 4 | N#Cc1cc(N)c(-c2nc3ccccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | c(N) |
<|startoftext|><L>N#Cc1ccc(-c2nc3ccccc3s2<mask_1:2>1<mask_1:2> | 3 | 23 | 2 | )cc | 2 | N#Cc1ccc(-c2nc3ccccc3s2)o1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | )o |
<|startoftext|><L>N#Cc1ccc(-c2nc3ccccc3s2)c<mask_1:4>c1<mask_1:4> | 0 | 25 | 4 | 4 | N#Cc1ccc(-c2nc3ccccc3s2)c(Cl)c1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | (Cl) |
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<|startoftext|><L>N#Cc1ccc(-c2<mask_1:2>cccc3s2)cc1<mask_1:2> | 4 | 12 | 2 | nc3c | 2 | N#Cc1ccc(-c2c3cccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | c3 |
<|startoftext|><L>N#Cc1<mask_1:4>cc(-c2nc3ccccc3s2)cc1<mask_1:4> | 1 | 5 | 4 | c | 4 | N#Cc1c(F)cc(-c2nc3ccccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | c(F) |
<|startoftext|><L>N#Cc1ccc<mask_1:3>-c2nc3ccccc3s2)cc1<mask_1:3> | 1 | 8 | 3 | ( | 3 | N#Cc1ccc(OC-c2nc3ccccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | (OC |
<|startoftext|><L>N#Cc1ccc(-c2nc3ccccc<mask_1:1>2)cc1<mask_1:1> | 2 | 20 | 1 | 3s | 1 | N#Cc1ccc(-c2nc3ccccc32)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | 3 |
<|startoftext|><L>N#Cc1ccc(-c2nc<mask_1:2>ccc3s2)cc1<mask_1:2> | 3 | 14 | 2 | 3cc | 2 | N#Cc1ccc(-c2nc3sccc3s2)cc1 | N#Cc1ccc(-c2nc3ccccc3s2)cc1 | 3s |
<|startoftext|><L>O=C(CN1C(=O)<mask_1:4>C1=O)N1CCOCC1<mask_1:4> | 3 | 12 | 4 | COC | 4 | O=C(CN1C(=O)CCSCC1=O)N1CCOCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | CCSC |
<|startoftext|><L>O=C(CN1C(=O)COCC1=O)<mask_1:3>OCC1<mask_1:3> | 4 | 20 | 3 | N1CC | 3 | O=C(CN1C(=O)COCC1=O)N1COCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | N1C |
<|startoftext|><L>O=C(CN1C(=O)COCC1=O)N1CC<mask_1:1>C1<mask_1:1> | 2 | 24 | 1 | OC | 1 | O=C(CN1C(=O)COCC1=O)N1CCCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | C |
<|startoftext|><L>O=C(CN1C(=O)COCC1=O)N<mask_1:2>OCC1<mask_1:2> | 3 | 21 | 2 | 1CC | 2 | O=C(CN1C(=O)COCC1=O)N1COCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | 1C |
<|startoftext|><L><mask_1:1>C(CN1C(=O)COCC1=O)N1CCOCC1<mask_1:1> | 2 | 0 | 1 | O= | 1 | CC(CN1C(=O)COCC1=O)N1CCOCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | C |
<|startoftext|><L>O=C(CN1C(=O)COCC1=O)N<mask_1:3>COCC1<mask_1:3> | 2 | 21 | 3 | 1C | 3 | O=C(CN1C(=O)COCC1=O)NC1CCOCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | C1C |
<|startoftext|><L>O=C(CN1<mask_1:4>(=O)COCC1=O)N1CCOCC1<mask_1:4> | 1 | 7 | 4 | C | 4 | O=C(CN1CCNC(=O)COCC1=O)N1CCOCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | CCNC |
<|startoftext|><L>O=C(CN1C(=O)C<mask_1:3>OCC1=O)N1CCOCC1<mask_1:3> | 0 | 13 | 3 | 3 | O=C(CN1C(=O)CCCCOCC1=O)N1CCOCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | CCC |
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<|startoftext|><L>O=C(CN1C(=O)COCC1<mask_1:2>O)N1CCOCC1<mask_1:2> | 1 | 17 | 2 | = | 2 | O=C(CN1C(=O)COCC1=NO)N1CCOCC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | =N |
<|startoftext|><L>O=C(CN1C(=O)COCC1=O)N1CC<mask_1:4>CC1<mask_1:4> | 1 | 24 | 4 | O | 4 | O=C(CN1C(=O)COCC1=O)N1CCN(C)CC1 | O=C(CN1C(=O)COCC1=O)N1CCOCC1 | N(C) |
<|startoftext|><L>CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2cc<mask_1:5>c2)c1<mask_1:5> | 2 | 33 | 5 | cc | 5 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccc(F)cc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | c(F)c |
<|startoftext|><L>CN(Cc1cnn(C)c1)C(=O<mask_1:5>c1cccc(Oc2ccccc2)c1<mask_1:5> | 2 | 19 | 5 | )N | 5 | CN(Cc1cnn(C)c1)C(=O)NCCOc1cccc(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | )NCCO |
<|startoftext|><L><mask_1:6>1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1<mask_1:6> | 5 | 0 | 6 | CN(Cc | 6 | CCN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | CCN(Cc |
<|startoftext|><L>CN(Cc1cnn(C)c<mask_1:5>=O)Nc1cccc(Oc2ccccc2)c1<mask_1:5> | 4 | 13 | 5 | 1)C( | 5 | CN(Cc1cnn(C)c1)CC(=O)Nc1cccc(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | 1)CC( |
<|startoftext|><L>CN(Cc1cnn(C)c1)C(=O)Nc1cccc(O<mask_1:1>c2ccccc2)c1<mask_1:1> | 0 | 29 | 1 | 1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(OCc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | C |
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<|startoftext|><L>C<mask_1:1>Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1<mask_1:1> | 2 | 1 | 1 | N( | 1 | C(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | ( |
<|startoftext|><L>CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2c<mask_1:6>cc2)c1<mask_1:6> | 2 | 32 | 6 | cc | 6 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccc(Cl)cc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | cc(Cl) |
<|startoftext|><L>CN(Cc1cnn(C)c1)C(=O)Nc<mask_1:4>(Oc2ccccc2)c1<mask_1:4> | 5 | 22 | 4 | 1cccc | 4 | CN(Cc1cnn(C)c1)C(=O)Nc1cnn(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | 1cnn |
<|startoftext|><L>C<mask_1:2>1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1<mask_1:2> | 4 | 1 | 2 | N(Cc | 2 | C(c1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | (c |
<|startoftext|><L>CN(Cc1cnn(C)c1)<mask_1:5>)Nc1cccc(Oc2ccccc2)c1<mask_1:5> | 4 | 15 | 5 | C(=O | 5 | CN(Cc1cnn(C)c1)CC(=O)Nc1cccc(Oc2ccccc2)c1 | CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Oc2ccccc2)c1 | CC(=O |
<|startoftext|><L>Cc1<mask_1:2>CN2CCc3ncnc(N(C)C)c3C2)n1<mask_1:2> | 4 | 3 | 2 | noc( | 2 | Cc1n(CN2CCc3ncnc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | n( |
<|startoftext|><L>Cc1noc(CN2CCc3<mask_1:4>nc(N(C)C)c3C2)n1<mask_1:4> | 2 | 14 | 4 | nc | 4 | Cc1noc(CN2CCc3[nH]nc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | [nH] |
<|startoftext|><L>Cc1noc(CN2CCc3ncnc(<mask_1:1>C)c3C2)n1<mask_1:1> | 4 | 19 | 1 | N(C) | 1 | Cc1noc(CN2CCc3ncnc(OC)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | O |
<|startoftext|><L>Cc1noc(CN2CCc<mask_1:2>nc(N(C)C)c3C2)n1<mask_1:2> | 3 | 13 | 2 | 3nc | 2 | Cc1noc(CN2CCc3onc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | 3o |
<|startoftext|><L>Cc1noc(<mask_1:4>2CCc3ncnc(N(C)C)c3C2)n1<mask_1:4> | 2 | 7 | 4 | CN | 4 | Cc1noc(CCCN2CCc3ncnc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | CCCN |
<|startoftext|><L>Cc1noc(<mask_1:2>CCc3ncnc(N(C)C)c3C2)n1<mask_1:2> | 3 | 7 | 2 | CN2 | 2 | Cc1noc(N2CCc3ncnc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | N2 |
<|startoftext|><L>Cc1noc(CN2<mask_1:4>3ncnc(N(C)C)c3C2)n1<mask_1:4> | 3 | 10 | 4 | CCc | 4 | Cc1noc(CN2CCOc3ncnc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | CCOc |
<|startoftext|><L>Cc1noc(<mask_1:4>2CCc3ncnc(N(C)C)c3C2)n1<mask_1:4> | 2 | 7 | 4 | CN | 4 | Cc1noc(CCCN2CCc3ncnc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | CCCN |
<|startoftext|><L>Cc1noc(CN2CCc3ncnc(<mask_1:4>)C)c3C2)n1<mask_1:4> | 3 | 19 | 4 | N(C | 4 | Cc1noc(CN2CCc3ncnc(NC(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | NC(C |
<|startoftext|><L>Cc1noc(C<mask_1:4>Cc3ncnc(N(C)C)c3C2)n1<mask_1:4> | 3 | 8 | 4 | N2C | 4 | Cc1noc(CCN2CCc3ncnc(N(C)C)c3C2)n1 | Cc1noc(CN2CCc3ncnc(N(C)C)c3C2)n1 | CN2C |
<|startoftext|><L>CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H<mask_1:4>N23)cc1<mask_1:4> | 5 | 36 | 4 | ](C)C | 4 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)N23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | ](C) |
<|startoftext|><L>CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C<mask_1:7>)CN23)cc1<mask_1:7> | 0 | 39 | 7 | 7 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C(C)(C)C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | (C)(C)C |
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<|startoftext|><L>CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[<mask_1:1>](C)CN23)cc1<mask_1:1> | 4 | 32 | 1 | C@@H | 1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | C |
<|startoftext|><L>CSc1ccc([C@@H](C<mask_1:7>2=NC[C@H]3CC[C@@H](C)CN23)cc1<mask_1:7> | 3 | 16 | 7 | )NC | 7 | CSc1ccc([C@@H](C)C(=O)C2=NC[C@H]3CC[C@@H](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | )C(=O)C |
<|startoftext|><L>CSc1ccc([C@@H](C)NC2=NC[C@<mask_1:7>C@@H](C)CN23)cc1<mask_1:7> | 6 | 26 | 7 | H]3CC[ | 7 | CSc1ccc([C@@H](C)NC2=NC[C@@H]3CC[C@@H](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | @H]3CC[ |
<|startoftext|><L>CSc1ccc([C@@H](C)NC2=NC[C<mask_1:2>H]3CC[C@@H](C)CN23)cc1<mask_1:2> | 1 | 25 | 2 | @ | 2 | CSc1ccc([C@@H](C)NC2=NC[C@@H]3CC[C@@H](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | @@ |
<|startoftext|><L>CSc1ccc(<mask_1:2>C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1<mask_1:2> | 7 | 8 | 2 | [C@@H]( | 2 | CSc1ccc(C(C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | C( |
<|startoftext|><L>CSc1ccc([C@@H](C)NC2=<mask_1:3>H]3CC[C@@H](C)CN23)cc1<mask_1:3> | 5 | 21 | 3 | NC[C@ | 3 | CSc1ccc([C@@H](C)NC2=N[CH]3CC[C@@H](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | N[C |
<|startoftext|><L>CSc1ccc([C@@H]<mask_1:5>C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1<mask_1:5> | 1 | 14 | 5 | ( | 5 | CSc1ccc([C@@H](C)N(C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | (C)N( |
<|startoftext|><L>CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)c<mask_1:5>1<mask_1:5> | 1 | 46 | 5 | c | 5 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)c(Cl)c1 | CSc1ccc([C@@H](C)NC2=NC[C@H]3CC[C@@H](C)CN23)cc1 | (Cl)c |
<|startoftext|><L>CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]<mask_1:6>[C@H]2C[C@@H](O)C[C@H]2C1<mask_1:6> | 2 | 30 | 6 | 1C | 6 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H](CN)C1[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | (CN)C1 |
<|startoftext|><L>CN(<mask_1:2>2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1<mask_1:2> | 8 | 3 | 2 | C(=O)c1c | 2 | CN(c12c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | c1 |
<|startoftext|><L>CN(C<mask_1:6>)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1<mask_1:6> | 3 | 4 | 6 | (=O | 6 | CN(CCNC(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CNC(=O |
<|startoftext|><L>CN(C(=O)c1c2c(nn1C)CCC<mask_1:6>1C[C@H]2C[C@@H](O)C[C@H]2C1<mask_1:6> | 8 | 22 | 6 | C2)[C@H] | 6 | CN(C(=O)c1c2c(nn1C)CCCCCC2)C1C[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CCC2)C |
<|startoftext|><L>CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C<mask_1:6>O)C[C@H]2C1<mask_1:6> | 7 | 39 | 6 | [C@@H]( | 6 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | [C@H]( |
<|startoftext|><L>CN(C(=O)<mask_1:7>2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1<mask_1:7> | 3 | 8 | 7 | c1c | 7 | CN(C(=O)/C=C/c12c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | /C=C/c1 |
<|startoftext|><L>CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H]<mask_1:6>H]2C1<mask_1:6> | 7 | 45 | 6 | (O)C[C@ | 6 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[CH]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | (O)C[C |
<|startoftext|><L>CN(C(=O)c1c2c(nn1C)CCCC2)[C<mask_1:8>C@H]2C[C@@H](O)C[C@H]2C1<mask_1:8> | 6 | 27 | 8 | @H]1C[ | 8 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@@H]1CC[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | @@H]1CC[ |
<|startoftext|><L>CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]<mask_1:4>H](O)C[C@H]2C1<mask_1:4> | 6 | 37 | 4 | 2C[C@@ | 4 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2[C@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | 2[C@ |
<|startoftext|><L><mask_1:3>(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1<mask_1:3> | 2 | 0 | 3 | CN | 3 | CCN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CN(C(=O)c1c2c(nn1C)CCCC2)[C@H]1C[C@H]2C[C@@H](O)C[C@H]2C1 | CCN |
<|startoftext|><L><mask_1:2>ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1<mask_1:2> | 3 | 0 | 2 | Cc1 | 2 | c1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | c1 |
<|startoftext|><L>Cc1ccc(C(=O)OCc2ccc(-n3cc<mask_1:4>n3)cc2)o1<mask_1:4> | 1 | 25 | 4 | c | 4 | Cc1ccc(C(=O)OCc2ccc(-n3ccc(C)n3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | c(C) |
<|startoftext|><L>Cc1ccc(C(=O)OCc2<mask_1:5>(-n3cccn3)cc2)o1<mask_1:5> | 3 | 16 | 5 | ccc | 5 | Cc1ccc(C(=O)OCc2cc(C)(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | cc(C) |
<|startoftext|><L>Cc<mask_1:3>ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1<mask_1:3> | 1 | 2 | 3 | 1 | 3 | Cc1ccccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | 1cc |
<|startoftext|><L>Cc1ccc(C(=O)OCc2ccc(-n3cc<mask_1:4>cn3)cc2)o1<mask_1:4> | 0 | 25 | 4 | 4 | Cc1ccc(C(=O)OCc2ccc(-n3cc(Br)cn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | (Br) |
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<|startoftext|><L>C<mask_1:4>c1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1<mask_1:4> | 0 | 1 | 4 | 4 | CCCCCc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | CCCC |
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<|startoftext|><L>Cc1ccc(C(=O)OCc2ccc(-n3cccn3)<mask_1:5>)o1<mask_1:5> | 3 | 29 | 5 | cc2 | 5 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2Cl)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | cc2Cl |
<|startoftext|><L>Cc1ccc(C<mask_1:5>=O)OCc2ccc(-n3cccn3)cc2)o1<mask_1:5> | 1 | 8 | 5 | ( | 5 | Cc1ccc(CCCNC(=O)OCc2ccc(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | CCNC( |
<|startoftext|><L>Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc<mask_1:2>1<mask_1:2> | 3 | 31 | 2 | 2)o | 3 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | 2)o |
<|startoftext|><L>Cc1ccc(C(=O<mask_1:5>c2ccc(-n3cccn3)cc2)o1<mask_1:5> | 3 | 11 | 5 | )OC | 5 | Cc1ccc(C(=O)N(C)c2ccc(-n3cccn3)cc2)o1 | Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)o1 | )N(C) |
<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O<mask_1:6>)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2<mask_1:6> | 0 | 30 | 6 | 6 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)NC(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | )NC(=O |
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<|startoftext|><L>CC(C)N1C(=O)c<mask_1:8>[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2<mask_1:8> | 7 | 13 | 8 | 2ccccc2 | 8 | CC(C)N1C(=O)c2ccccc2N[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | 2ccccc2N |
<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12<mask_1:5>CN(C(=O)c1ccccc1F)C2<mask_1:5> | 0 | 46 | 5 | 5 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C)CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | CN(C) |
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<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1<mask_1:6>C2<mask_1:6> | 8 | 56 | 6 | ccccc1F) | 6 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccsc1)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | ccsc1) |
<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(<mask_1:1>C)CC2)C12CN(C(=O)c1ccccc1F)C2<mask_1:1> | 0 | 37 | 1 | 1 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(CC)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | C |
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<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C<mask_1:8>2)C12CN(C(=O)c1ccccc1F)C2<mask_1:8> | 3 | 38 | 8 | )CC | 8 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)C(=O)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | )C(=O)CC |
<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O)<mask_1:5>N(C)CC2)C12CN(C(=O)c1ccccc1F)C2<mask_1:5> | 4 | 31 | 5 | N2CC | 5 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | N2CCC |
<|startoftext|><L>CC(C)N1C(=O)c2ccccc2<mask_1:4>H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2<mask_1:4> | 3 | 20 | 4 | [C@ | 4 | CC(C)N1C(=O)c2ccccc2[C@@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | [C@@ |
<|startoftext|><L>CC(C)N1C(=O)c<mask_1:1>C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2<mask_1:1> | 8 | 13 | 1 | 2ccccc2[ | 1 | CC(C)N1C(=O)c[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | [ |
<|startoftext|><L>CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2C<mask_1:1>C2)C12CN(C(=O)c1ccccc1F)C2<mask_1:1> | 6 | 34 | 1 | CN(C)C | 1 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCC2)C12CN(C(=O)c1ccccc1F)C2 | CC(C)N1C(=O)c2ccccc2[C@H](C(=O)N2CCN(C)CC2)C12CN(C(=O)c1ccccc1F)C2 | C |
<|startoftext|><L>COC(=O)[C@@H](NC(=O)c1ccnc(OC<mask_1:4>CC2)c1)C(C)C<mask_1:4> | 2 | 29 | 4 | C2 | 4 | COC(=O)[C@@H](NC(=O)c1ccnc(OC2CCCCC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | 2CCC |
<|startoftext|><L>COC(<mask_1:6>)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C<mask_1:6> | 2 | 4 | 6 | =O | 6 | COC(=O)N(C)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | =O)N(C |
<|startoftext|><L>COC(=O)[C@@H](NC(=O)<mask_1:4>c1ccnc(OCC2CC2)c1)C(C)C<mask_1:4> | 0 | 20 | 4 | 4 | COC(=O)[C@@H](NC(=O)NCCNc1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | NCCN |
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<|startoftext|><L>COC(=O)[C@@H](N<mask_1:3>C(=O)c1ccnc(OCC2CC2)c1)C(C)C<mask_1:3> | 0 | 15 | 3 | 3 | COC(=O)[C@@H](NCCNC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | CCN |
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<|startoftext|><L>C<mask_1:4>=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C<mask_1:4> | 3 | 1 | 4 | OC( | 4 | CCOC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC( |
<|startoftext|><L>COC(=O)[C@@<mask_1:5>NC(=O)c1ccnc(OCC2CC2)c1)C(C)C<mask_1:5> | 3 | 11 | 5 | H]( | 5 | COC(=O)[C@@](C)(NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | ](C)( |
<|startoftext|><L>COC(=O)[C@@H](NC(=<mask_1:6>O)c1ccnc(OCC2CC2)c1)C(C)C<mask_1:6> | 0 | 18 | 6 | 6 | COC(=O)[C@@H](NC(=S)NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | S)NC(= |
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<|startoftext|><L>COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC<mask_1:5>2)c1)C(C)C<mask_1:5> | 0 | 33 | 5 | 5 | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CCN(C)C2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | N(C)C |
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<|startoftext|><L>COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1<mask_1:2>C(C)C<mask_1:2> | 1 | 37 | 2 | ) | 2 | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)CC(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | )C |
<|startoftext|><L>COC<mask_1:2>[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C<mask_1:2> | 4 | 3 | 2 | (=O) | 2 | COCCC[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | COC(=O)[C@@H](NC(=O)c1ccnc(OCC2CC2)c1)C(C)C | CC |