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<|startoftext|><L>Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3O<mask_1:2>nc2)n1<mask_1:2> | 6 | 34 | 2 | Cc2ccc | 2 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OC2nc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | C2 |
<|startoftext|><L>Cc1csc(CN2CCO[C@H]3CC[C@H]<mask_1:4>C@H]3OCc2cccnc2)n1<mask_1:4> | 2 | 26 | 4 | 2[ | 4 | Cc1csc(CN2CCO[C@H]3CC[C@H]2CC[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | 2CC[ |
<|startoftext|><L>Cc1csc(CN2CCO[C@H]<mask_1:2>C@H]2[C@H]3OCc2cccnc2)n1<mask_1:2> | 4 | 18 | 2 | 3CC[ | 2 | Cc1csc(CN2CCO[C@H]3[C@H]2[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | 3[ |
<|startoftext|><L><mask_1:5>Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1<mask_1:5> | 0 | 0 | 5 | 5 | CC(C)Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | CC(C) |
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<|startoftext|><L>Cc1csc(CN2CCO[C@H]3CC[C@H]2<mask_1:3>]3OCc2cccnc2)n1<mask_1:3> | 4 | 27 | 3 | [C@H | 3 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | [C@ |
<|startoftext|><L>Cc1csc(CN2CCO[C@H]3C<mask_1:5>2[C@H]3OCc2cccnc2)n1<mask_1:5> | 6 | 20 | 5 | C[C@H] | 5 | Cc1csc(CN2CCO[C@H]3C[C@H]2[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | [C@H] |
<|startoftext|><L>Cc1csc(CN2CCO[C@H]3CC[C@H<mask_1:5>[C@H]3OCc2cccnc2)n1<mask_1:5> | 2 | 25 | 5 | ]2 | 5 | Cc1csc(CN2CCO[C@H]3CC[C@H]2COC[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | ]2COC |
<|startoftext|><L>Cc1csc(CN2CCO<mask_1:4>H]3CC[C@H]2[C@H]3OCc2cccnc2)n1<mask_1:4> | 3 | 13 | 4 | [C@ | 4 | Cc1csc(CN2CCO[C@@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | [C@@ |
<|startoftext|><L>Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2c<mask_1:4>cnc2)n1<mask_1:4> | 1 | 38 | 4 | c | 4 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cc(C)cnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | c(C) |
<|startoftext|><L>Cc1csc(CN2CCO[C@H]3<mask_1:6>H]2[C@H]3OCc2cccnc2)n1<mask_1:6> | 5 | 19 | 6 | CC[C@ | 6 | Cc1csc(CN2CCO[C@H]3CC[C@@H]2[C@H]3OCc2cccnc2)n1 | Cc1csc(CN2CCO[C@H]3CC[C@H]2[C@H]3OCc2cccnc2)n1 | CC[C@@ |
<|startoftext|><L><mask_1:5>Cn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21<mask_1:5> | 3 | 0 | 5 | C=C | 5 | CC(C)Cn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | CC(C) |
<|startoftext|><L>C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc<mask_1:3>21<mask_1:3> | 6 | 39 | 3 | 2ccccc | 3 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2sc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | 2sc |
<|startoftext|><L>C<mask_1:6>1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21<mask_1:6> | 4 | 1 | 6 | =CCn | 6 | CC(=O)n1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | C(=O)n |
<|startoftext|><L>C=CCn1c(COc2ccc(C<mask_1:7>nnc1SCC(=O)N1CCc2ccccc21<mask_1:7> | 6 | 17 | 7 | l)cc2) | 7 | C=CCn1c(COc2ccc(Cl)cc2C)nnc1SCC(=O)N1CCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | l)cc2C) |
<|startoftext|><L>C=CC<mask_1:7>c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21<mask_1:7> | 2 | 4 | 7 | n1 | 7 | C=CC(=O)Nn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | (=O)Nn1 |
<|startoftext|><L>C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)<mask_1:7>ccccc21<mask_1:7> | 6 | 34 | 7 | N1CCc2 | 7 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | N1CCCc2 |
<|startoftext|><L>C=CCn1c(COc2ccc(Cl)cc2)nnc1SC<mask_1:2>)N1CCc2ccccc21<mask_1:2> | 4 | 29 | 2 | C(=O | 2 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SC(C)N1CCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | (C |
<|startoftext|><L>C=CCn1c(COc2ccc(Cl)cc2)nnc1SC<mask_1:2>)N1CCc2ccccc21<mask_1:2> | 4 | 29 | 2 | C(=O | 2 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SC(C)N1CCc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | (C |
<|startoftext|><L>C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1C<mask_1:6>c2ccccc21<mask_1:6> | 1 | 37 | 6 | C | 6 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCC(=O)c2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | CC(=O) |
<|startoftext|><L>C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=<mask_1:4>Cc2ccccc21<mask_1:4> | 5 | 32 | 4 | O)N1C | 4 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1Cc2ccccc21 | C=CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)N1CCc2ccccc21 | O)N1 |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nn<mask_1:3>ccn12<mask_1:3> | 4 | 39 | 3 | c2cc | 3 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2sccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | c2s |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)<mask_1:4>nc2ccccn12<mask_1:4> | 3 | 35 | 4 | c1n | 4 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)Cc1nnc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | Cc1n |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nn<mask_1:7>ccn12<mask_1:7> | 4 | 39 | 7 | c2cc | 7 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2c(C)cccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | c2c(C)c |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)cc1C(=O)N<mask_1:3>C)c1nnc2ccccn12<mask_1:3> | 6 | 27 | 3 | [C@H]( | 3 | Cc1ccc(S(C)(=O)=O)cc1C(=O)NCC(C)c1nnc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | CC( |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O<mask_1:7>1C(=O)N[C@H](C)c1nnc2ccccn12<mask_1:7> | 3 | 17 | 7 | )cc | 7 | Cc1ccc(S(C)(=O)=O)c(Br)c1C(=O)N[C@H](C)c1nnc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | )c(Br)c |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc<mask_1:1>ccn12<mask_1:1> | 3 | 40 | 1 | 2cc | 1 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | 2 |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1<mask_1:7>c2ccccn12<mask_1:7> | 2 | 37 | 7 | nn | 7 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1cc(=O)nc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | cc(=O)n |
<|startoftext|><L>Cc1ccc(S(C<mask_1:5>)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12<mask_1:5> | 4 | 10 | 5 | )(=O | 4 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | )(=O |
<|startoftext|><L>Cc1ccc(S(C)(=O)=O)c<mask_1:3>N[C@H](C)c1nnc2ccccn12<mask_1:3> | 7 | 19 | 3 | c1C(=O) | 3 | Cc1ccc(S(C)(=O)=O)cc1CN[C@H](C)c1nnc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | c1C |
<|startoftext|><L>Cc1ccc(<mask_1:2>O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12<mask_1:2> | 6 | 7 | 2 | S(C)(= | 2 | Cc1ccc(C(O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | Cc1ccc(S(C)(=O)=O)cc1C(=O)N[C@H](C)c1nnc2ccccn12 | C( |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2<mask_1:4>cccc2C)c(OC)c1<mask_1:4> | 1 | 50 | 4 | c | 4 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2c(C)cccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | c(C) |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2<mask_1:2>(=O)c2ccccc2C)c(OC)c1<mask_1:2> | 5 | 39 | 2 | S(=O) | 2 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2CC(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | CC |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(O<mask_1:4>c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:4> | 2 | 25 | 4 | C) | 4 | COc1ccc([C@@H]2CC(c3ccc(OCCO)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | CCO) |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(OC)c(<mask_1:5>c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:5> | 3 | 29 | 5 | OC) | 5 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OCCO)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | OCCO) |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3c<mask_1:5>(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:5> | 7 | 21 | 5 | cc(OC)c | 5 | COc1ccc([C@@H]2CC(c3ccc(O)(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | cc(O) |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)<mask_1:5>1<mask_1:5> | 6 | 58 | 5 | c(OC)c | 5 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(O)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | c(O)c |
<|startoftext|><L><mask_1:1>c1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:1> | 2 | 0 | 1 | CO | 1 | Cc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | C |
<|startoftext|><L>COc1ccc(<mask_1:5>2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:5> | 6 | 8 | 5 | [C@@H] | 5 | COc1ccc([C@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | [C@H] |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN<mask_1:8>S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:8> | 1 | 38 | 8 | 2 | 8 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2C(=O)CNS(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | 2C(=O)CN |
<|startoftext|><L>COc1ccc([C@@H]2CC(c3ccc(OC)<mask_1:2>)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1<mask_1:2> | 4 | 27 | 2 | c(OC | 2 | COc1ccc([C@@H]2CC(c3ccc(OC)(O)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | COc1ccc([C@@H]2CC(c3ccc(OC)c(OC)c3)=NN2S(=O)(=O)c2ccccc2C)c(OC)c1 | (O |
<|startoftext|><L><mask_1:1>CCCSc1nnnn1-c1cccc(C)c1<mask_1:1> | 0 | 0 | 1 | 1 | CCCCSc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | C |
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<|startoftext|><L>CCCSc1nnnn1-c1cccc(C<mask_1:3>1<mask_1:3> | 2 | 20 | 3 | )c | 3 | CCCSc1nnnn1-c1cccc(Cl)c1 | CCCSc1nnnn1-c1cccc(C)c1 | l)c |
<|startoftext|><L>CCCSc1nnnn1-c1cccc<mask_1:3>C)c1<mask_1:3> | 1 | 18 | 3 | ( | 3 | CCCSc1nnnn1-c1cccc(OCC)c1 | CCCSc1nnnn1-c1cccc(C)c1 | (OC |
<|startoftext|><L>C<mask_1:1>CCSc1nnnn1-c1cccc(C)c1<mask_1:1> | 0 | 1 | 1 | 1 | C=CCSc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | = |
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<|startoftext|><L>C<mask_1:2>CSc1nnnn1-c1cccc(C)c1<mask_1:2> | 1 | 1 | 2 | C | 2 | C#CCSc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | #C |
<|startoftext|><L>CC<mask_1:3>CSc1nnnn1-c1cccc(C)c1<mask_1:3> | 0 | 2 | 3 | 3 | CCCCCCSc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | CCC |
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<|startoftext|><L>CCC<mask_1:2>nnnn1-c1cccc(C)c1<mask_1:2> | 3 | 3 | 2 | Sc1 | 2 | CCCc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | c1 |
<|startoftext|><L>CCCSc1nnnn1-c1cc<mask_1:3>cc(C)c1<mask_1:3> | 0 | 16 | 3 | 3 | CCCSc1nnnn1-c1cc(C)cc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | (C) |
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<|startoftext|><L>C<mask_1:2>CCSc1nnnn1-c1cccc(C)c1<mask_1:2> | 0 | 1 | 2 | 2 | CCCCCSc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | CC |
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<|startoftext|><L>CCCS<mask_1:3>nnnn1-c1cccc(C)c1<mask_1:3> | 2 | 4 | 3 | c1 | 3 | CCCSCc1nnnn1-c1cccc(C)c1 | CCCSc1nnnn1-c1cccc(C)c1 | Cc1 |
<|startoftext|><L>Cn1cc(B<mask_1:4>cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1<mask_1:4> | 2 | 7 | 4 | r) | 4 | Cn1cc(Br)cccc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | r)cc |
<|startoftext|><L>Cn1cc(Br)cc1C(=O)NC[C<mask_1:2>CC(=O)N(C2CC2)C1<mask_1:2> | 4 | 21 | 2 | @H]1 | 2 | Cn1cc(Br)cc1C(=O)NC[C]1CC(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | ]1 |
<|startoftext|><L>Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(<mask_1:6>2)C1<mask_1:6> | 4 | 33 | 6 | C2CC | 6 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(c2ccsc2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | c2ccsc |
<|startoftext|><L>Cn1cc(Br)cc1<mask_1:2>NC[C@H]1CC(=O)N(C2CC2)C1<mask_1:2> | 5 | 12 | 2 | C(=O) | 2 | Cn1cc(Br)cc1C=NC[C@H]1CC(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | C= |
<|startoftext|><L>Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(<mask_1:4>CC2)C1<mask_1:4> | 2 | 33 | 4 | C2 | 4 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CCCC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | C2CC |
<|startoftext|><L>Cn1cc(Br)cc1C(=O)NC[C@H]1C<mask_1:1>=O)N(C2CC2)C1<mask_1:1> | 2 | 26 | 1 | C( | 1 | Cn1cc(Br)cc1C(=O)NC[C@H]1C(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | ( |
<|startoftext|><L>Cn1c<mask_1:5>Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1<mask_1:5> | 2 | 4 | 5 | c( | 5 | Cn1c(O)c(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | (O)c( |
<|startoftext|><L>Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C<mask_1:3>2CC2)C1<mask_1:3> | 0 | 34 | 3 | 3 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(CCOC2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | COC |
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<|startoftext|><L>Cn1cc(Br)cc1C(=O)NC<mask_1:4>@H]1CC(=O)N(C2CC2)C1<mask_1:4> | 2 | 19 | 4 | [C | 4 | Cn1cc(Br)cc1C(=O)NCC[C@@H]1CC(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | C[C@ |
<|startoftext|><L>Cn1cc(Br)cc1C(=O)<mask_1:3>[C@H]1CC(=O)N(C2CC2)C1<mask_1:3> | 2 | 17 | 3 | NC | 3 | Cn1cc(Br)cc1C(=O)NCC[C@H]1CC(=O)N(C2CC2)C1 | Cn1cc(Br)cc1C(=O)NC[C@H]1CC(=O)N(C2CC2)C1 | NCC |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O<mask_1:6>2CCCC2)C1<mask_1:6> | 2 | 33 | 6 | )N | 6 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)NCCCN2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | )NCCCN |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C<mask_1:3>CCN(C(=O)N2CCCC2)C1<mask_1:3> | 5 | 20 | 3 | @H]1C | 3 | O=C(NCc1ccc(O)cc1)[CH]1CCN(C(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | H]1 |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@H]1CCCN(<mask_1:4>=O)N2CCCC2)C1<mask_1:4> | 2 | 29 | 4 | C( | 4 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(CCC(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | CCC( |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(<mask_1:5>=O)N2CCCC2)C1<mask_1:5> | 0 | 31 | 5 | 5 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)C(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | =O)C( |
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<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@<mask_1:6>CN(C(=O)N2CCCC2)C1<mask_1:6> | 5 | 21 | 6 | H]1CC | 6 | O=C(NCc1ccc(O)cc1)[C@@H]1CCCN(C(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | @H]1CC |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CC<mask_1:4>)C1<mask_1:4> | 3 | 38 | 4 | CC2 | 4 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | CCC2 |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=<mask_1:5>N2CCCC2)C1<mask_1:5> | 2 | 32 | 5 | O) | 5 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)CCCN2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | O)CCC |
<|startoftext|><L>O=C(NCc1ccc(O)cc<mask_1:2>)[C@H]1CCCN(C(=O)N2CCCC2)C1<mask_1:2> | 1 | 16 | 2 | 1 | 2 | O=C(NCc1ccc(O)cc1O)[C@H]1CCCN(C(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | 1O |
<|startoftext|><L>O=C(NCc1ccc(O)cc1)[C@H]1CC<mask_1:2>N(C(=O)N2CCCC2)C1<mask_1:2> | 1 | 26 | 2 | C | 2 | O=C(NCc1ccc(O)cc1)[C@H]1CCCCN(C(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | CC |
<|startoftext|><L>O=C(NC<mask_1:1>(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1<mask_1:1> | 5 | 6 | 1 | c1ccc | 1 | O=C(NC1(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | O=C(NCc1ccc(O)cc1)[C@H]1CCCN(C(=O)N2CCCC2)C1 | 1 |
<|startoftext|><L>Cc1ncc<mask_1:3>C(=O)c1cc(-c2ccc(F)cc2)[nH]n1<mask_1:3> | 4 | 6 | 3 | cc1N | 3 | Cc1nccn1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | n1N |
<|startoftext|><L>Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2<mask_1:2>[nH]n1<mask_1:2> | 1 | 32 | 2 | ) | 2 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2C)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | C) |
<|startoftext|><L>Cc1ncccc1NC(=O)c1cc(-c2<mask_1:1>(F)cc2)[nH]n1<mask_1:1> | 3 | 23 | 1 | ccc | 1 | Cc1ncccc1NC(=O)c1cc(-c2c(F)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | c |
<|startoftext|><L>Cc1ncccc1NC(=O)c1cc(-c2ccc(<mask_1:2>2)[nH]n1<mask_1:2> | 4 | 27 | 2 | F)cc | 2 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | F) |
<|startoftext|><L>Cc1ncccc1NC(<mask_1:5>c1cc(-c2ccc(F)cc2)[nH]n1<mask_1:5> | 3 | 12 | 5 | =O) | 5 | Cc1ncccc1NC(=O)CCc1cc(-c2ccc(F)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | =O)CC |
<|startoftext|><L><mask_1:2>ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1<mask_1:2> | 3 | 0 | 2 | Cc1 | 2 | c1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | c1 |
<|startoftext|><L>Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2<mask_1:4>n1<mask_1:4> | 5 | 32 | 4 | )[nH] | 4 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2Cl)on1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | Cl)o |
<|startoftext|><L>Cc1ncccc1NC(=O)c1cc(-c2ccc(<mask_1:5>2)[nH]n1<mask_1:5> | 4 | 27 | 5 | F)cc | 5 | Cc1ncccc1NC(=O)c1cc(-c2ccc(Br)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | Br)cc |
<|startoftext|><L>Cc1ncccc1NC(=O)c1cc(<mask_1:5>2ccc(F)cc2)[nH]n1<mask_1:5> | 2 | 20 | 5 | -c | 5 | Cc1ncccc1NC(=O)c1cc(CCCOc2ccc(F)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | CCCOc |
<|startoftext|><L>Cc1ncccc1NC(=O)c1c<mask_1:5>2ccc(F)cc2)[nH]n1<mask_1:5> | 4 | 18 | 5 | c(-c | 5 | Cc1ncccc1NC(=O)c1cc(COc2ccc(F)cc2)[nH]n1 | Cc1ncccc1NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 | c(COc |
<|startoftext|><L>CCC[C@H](NC(=O)[C@H<mask_1:8>OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:8> | 4 | 19 | 8 | ](C) | 8 | CCC[C@H](NC(=O)[C@H](CCSC)COC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | ](CCSC)C |
<|startoftext|><L>CCC[C@H](NC(=O)[<mask_1:3>H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:3> | 2 | 16 | 3 | C@ | 3 | CCC[C@H](NC(=O)[C@@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | C@@ |
<|startoftext|><L>CCC[C@H](NC(=O)[C@H](C)OC(<mask_1:6>=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:6> | 0 | 26 | 6 | 6 | CCC[C@H](NC(=O)[C@H](C)OC(=O)CC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | =O)CC( |
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<|startoftext|><L>CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c<mask_1:5>)c1ccccc1<mask_1:5> | 6 | 42 | 5 | (Br)c1 | 5 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(O)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | (O)c1 |
<|startoftext|><L>CCC[C@H](NC(=O)[C@H](C)<mask_1:5>1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:5> | 7 | 23 | 5 | OC(=O)c | 5 | CCC[C@H](NC(=O)[C@H](C)N(C)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | N(C)c |
<|startoftext|><L>CCC[C@H](NC<mask_1:1>O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:1> | 2 | 11 | 1 | (= | 1 | CCC[C@H](NC(O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | ( |
<|startoftext|><L>CCC[C@H](NC(=O)[<mask_1:7>(C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:7> | 4 | 16 | 7 | C@H] | 7 | CCC[C@H](NC(=O)[C@](C)C(C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | C@](C)C |
<|startoftext|><L>CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c<mask_1:5>c1<mask_1:5> | 8 | 47 | 5 | 1)c1cccc | 5 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)C1Cc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | 1)C1C |
<|startoftext|><L>CCC[C@H](NC(=<mask_1:8>H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:8> | 5 | 13 | 8 | O)[C@ | 8 | CCC[C@H](NC(=O)CC[C@@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | O)CC[C@@ |
<|startoftext|><L>CCC[C@H](<mask_1:4>(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1<mask_1:4> | 2 | 9 | 4 | NC | 4 | CCC[C@H](CCNC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCC[C@H](NC(=O)[C@H](C)OC(=O)c1c[nH]c(=O)c(Br)c1)c1ccccc1 | CCNC |
<|startoftext|><L>C<mask_1:6>1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1<mask_1:6> | 1 | 1 | 6 | c | 6 | CC(C)Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | C(C)Cc |
<|startoftext|><L>Cc1cc(CN2<mask_1:3>C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1<mask_1:3> | 0 | 9 | 3 | 3 | Cc1cc(CN2CCOC[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | CCO |
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<|startoftext|><L>Cc1cc(CN2C[<mask_1:6>CN(c4ncccc4C#N)C[C@@H]3C2)no1<mask_1:6> | 5 | 11 | 6 | C@H]3 | 6 | Cc1cc(CN2C[C@@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | C@@H]3 |
<|startoftext|><L>Cc1<mask_1:5>CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1<mask_1:5> | 3 | 3 | 5 | cc( | 5 | Cc1cc(CCCN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | cc(CC |
<|startoftext|><L>Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C<mask_1:2>3C2)no1<mask_1:2> | 4 | 34 | 2 | @@H] | 2 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | @] |
<|startoftext|><L>Cc1cc(C<mask_1:4>H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1<mask_1:4> | 6 | 7 | 4 | N2C[C@ | 4 | Cc1cc(C2[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | 2[C@ |
<|startoftext|><L>Cc1cc(CN2C[C@H]3CN<mask_1:4>ccc4C#N)C[C@@H]3C2)no1<mask_1:4> | 5 | 18 | 4 | (c4nc | 4 | Cc1cc(CN2C[C@H]3CN(c4sccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | (c4s |
<|startoftext|><L>Cc1cc(CN2C[C@H]3CN(c4nccc<mask_1:4>)C[C@@H]3C2)no1<mask_1:4> | 5 | 25 | 4 | c4C#N | 4 | Cc1cc(CN2C[C@H]3CN(c4ncccc4Cl)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | c4Cl |
<|startoftext|><L>Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N<mask_1:5>)C[C@@H]3C2)no1<mask_1:5> | 0 | 30 | 5 | 5 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C(=O)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | )C(=O |
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<|startoftext|><L>Cc1cc(CN2C[C<mask_1:6>CN(c4ncccc4C#N)C[C@@H]3C2)no1<mask_1:6> | 4 | 12 | 6 | @H]3 | 6 | Cc1cc(CN2C[C@@H]3CCN(c4ncccc4C#N)C[C@@H]3C2)no1 | Cc1cc(CN2C[C@H]3CN(c4ncccc4C#N)C[C@@H]3C2)no1 | @@H]3C |