jarod0411/cm_v6_idx6 · Datasets at Hugging Face

prompt stringlengths 49 215	first_mask_count int64 0 16	first_start_index int64 0 156	first_mask_gen_count int64 1 16	first_mask_tokens stringlengths 0 16	first_mask_gen_count_real int64 0 18	generated_smiles stringlengths 12 189	original_smiles stringlengths 12 175	generated_tokens stringlengths 0 18
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O<mask_1:4>)C(C)(C)c2ccccc2)CC1<mask_1:4>	0	23	4		4	Cn1nccc1C(=O)N1CCN(C(=O)N(C)C(C)(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	)N(C
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C<mask_1:5>)C(C)(C)c2ccccc2)CC1<mask_1:5>	3	20	5	(=O	5	Cn1nccc1C(=O)N1CCN(C(C)(C)C(C)(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	(C)(C
<\|startoftext\|><L>Cn1nc<mask_1:6>c1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1<mask_1:6>	1	5	6	c	6	Cn1nc(C#N)cc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	(C#N)c
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc<mask_1:5>)CC1<mask_1:5>	1	38	5	2	5	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)N(C)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	2)N(C
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C<mask_1:2>2ccccc2)CC1<mask_1:2>	5	27	2	)(C)c	2	Cn1nccc1C(=O)N1CCN(C(=O)C(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	)c
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(<mask_1:6>=O)C(C)(C)c2ccccc2)CC1<mask_1:6>	2	19	6	C(	6	Cn1nccc1C(=O)N1CCN(S(=O)(=O)C(C)(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	S(=O)(
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O<mask_1:3>(C)c2ccccc2)CC1<mask_1:3>	5	23	3	)C(C)	3	Cn1nccc1C(=O)N1CCN(C(=O)CN(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	)CN
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(<mask_1:3>(C)c2ccccc2)CC1<mask_1:3>	2	26	3	C)	3	Cn1nccc1C(=O)N1CCN(C(=O)C(C)N(C)c2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	C)N
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C)<mask_1:4>c2ccccc2)CC1<mask_1:4>	3	28	4	(C)	4	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)Cc2ccccc2)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	(C)C
<\|startoftext\|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2<mask_1:3>C1<mask_1:3>	2	39	3	)C	3	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2F)CC1	Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1	F)C
<\|startoftext\|><L>O=C(O)[C@H](CNC(<mask_1:8>)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:8>	2	16	8	=O	8	O=C(O)[C@H](CNC(=O)NC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	=O)NC(=O
<\|startoftext\|><L>O=C(O)[C@<mask_1:8>(CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:8>	2	9	8	H]	8	O=C(O)[C@@H](O)CN(CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	@H](O)CN
<\|startoftext\|><L>O=C(O)[C@H](CN<mask_1:3>@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:3>	7	14	3	C(=O)[C	3	O=C(O)[C@H](CNC[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	C[C
<\|startoftext\|><L>O=C(O)[C@H<mask_1:6>)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:6>	8	10	6	](CNC(=O	6	O=C(O)[C@H](CN(O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	](CN(O
<\|startoftext\|><L>O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]2<mask_1:8>C1<mask_1:8>	6	52	8	1)CC1C	8	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CCOC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	1)CC1CCO
<\|startoftext\|><L>O=C(O)[C@H](CNC(<mask_1:7>=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:7>	0	16	7		7	O=C(O)[C@H](CNC(=O)CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	=O)CNC(
<\|startoftext\|><L>O=C(O)[C@<mask_1:9>=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:9>	7	9	9	H](CNC(	9	O=C(O)[C@@H](CCNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	@H](CCNC(
<\|startoftext\|><L>O=C(O)[C@H](C<mask_1:3>)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:3>	5	13	3	NC(=O	3	O=C(O)[C@H](C(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	(=O
<\|startoftext\|><L>O=C(O)[C@<mask_1:9>O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:9>	8	9	9	H](CNC(=	9	O=C(O)[C@@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	@H](CNC(=
<\|startoftext\|><L>O=C<mask_1:3>](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:3>	7	3	3	(O)[C@H	3	O=C[S@](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1	[S@
<\|startoftext\|><L>Cc1ccccc1-c1nnn(<mask_1:6>c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:6>	5	16	6	CCCn2	6	Cc1ccccc1-c1nnn(CCCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	CCCCn2
<\|startoftext\|><L>Cc1ccccc1-c1nnn(CC<mask_1:7>O)c3c(ncn3C)n(C)c2=O)n1<mask_1:7>	6	18	7	Cn2c(=	7	Cc1ccccc1-c1nnn(CCOc2c(C=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Oc2c(C=
<\|startoftext\|><L>Cc1ccccc1-c1nnn(CCCn2c(<mask_1:6>O)c3c(ncn3C)n(C)c2=O)n1<mask_1:6>	1	23	6	=	6	Cc1ccccc1-c1nnn(CCCn2c(=O)c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	=O)c(=
<\|startoftext\|><L>Cc1ccccc1-c1nnn(CC<mask_1:7>Cn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:7>	0	18	7		7	Cc1ccccc1-c1nnn(CC(=O)NCCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	(=O)NCC
<\|startoftext\|><L>Cc1ccccc1-c1nnn(<mask_1:5>CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:5>	1	16	5	C	5	Cc1ccccc1-c1nnn(C(=O)CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	C(=O)
<\|startoftext\|><L>Cc1ccccc1-c1nnn(C<mask_1:5>c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:5>	4	17	5	CCn2	5	Cc1ccccc1-c1nnn(CCCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	CCCn2
<\|startoftext\|><L>Cc1ccccc1-c1nnn(CCCn2c(=<mask_1:1>O)c3c(ncn3C)n(C)c2=O)n1<mask_1:1>	0	24	1		1	Cc1ccccc1-c1nnn(CCCn2c(=SO)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	S
<\|startoftext\|><L>Cc1ccccc1-c1nnn<mask_1:6>(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:6>	7	15	6	(CCCn2c	6	Cc1ccccc1-c1nnn(CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	(CCn2c
<\|startoftext\|><L>Cc1ccccc1<mask_1:3>1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:3>	2	9	3	-c	3	Cc1ccccc1OCc1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	OCc
<\|startoftext\|><L>Cc1ccccc1-c1nn<mask_1:3>Cn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:3>	4	14	3	n(CC	3	Cc1ccccc1-c1nnn(CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1	n(C
<\|startoftext\|><L>C[C@@H](C(=O)NCCSCc1ccccc1C<mask_1:7>1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:7>	5	27	7	l)N(c	7	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(CCc1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	l)N(CCc
<\|startoftext\|><L>C[C@@H](C(=O)NCCSCc1cc<mask_1:4>cc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:4>	1	22	4	c	4	C[C@@H](C(=O)NCCSCc1cc(F)ccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	(F)c
<\|startoftext\|><L>C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(<mask_1:8>c2c(c1)OCCO2)S(C)(=O)=O<mask_1:8>	4	31	8	c1cc	8	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1cc(Cl)c2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	c1cc(Cl)
<\|startoftext\|><L>C[C@@<mask_1:7>(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:7>	2	5	7	H]	7	C[C@@H](CO)N(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	H](CO)N
<\|startoftext\|><L>C[C@@H<mask_1:7>C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:7>	2	6	7	](	7	C[C@@H](C(=O)C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	](C(=O)
<\|startoftext\|><L>C[C@@H](C<mask_1:4>CSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:4>	6	9	4	(=O)NC	4	C[C@@H](C(=O)CSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	(=O)
<\|startoftext\|><L>C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1<mask_1:2>OCCO2)S(C)(=O)=O<mask_1:2>	1	41	2	)	2	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)COCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	)C
<\|startoftext\|><L>C[C@@H](C(=O)NCCSCc1ccccc<mask_1:8>c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:8>	6	25	8	1Cl)N(	8	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(CCc1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	1Cl)N(CC
<\|startoftext\|><L>C[C@@H](C(=O)NCC<mask_1:3>ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:3>	4	16	3	SCc1	3	C[C@@H](C(=O)NCCOc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	Oc1
<\|startoftext\|><L>C[<mask_1:6>(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:6>	5	2	6	C@@H]	6	C[C@](C)(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O	C@](C)
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O<mask_1:7>)CC2)C(=O)O1<mask_1:7>	2	56	7	-]	7	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC(O)CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	-])CC(O
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2C<mask_1:10>(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:10>	8	25	10	CN(c3ccc	10	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3nc(C)(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	CN(c3nc(C)
<\|startoftext\|><L>C[C@@H]<mask_1:7>C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:7>	1	7	7	1	7	C[C@@H]1C(=O)CC[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	1C(=O)C
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])C<mask_1:7>O1<mask_1:7>	8	60	7	C2)C(=O)	8	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C2)C(=O)
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C<mask_1:3>c3[N+](=O)[O-])CC2)C(=O)O1<mask_1:3>	9	35	3	(F)(F)F)c	3	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(Cl)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	l)c
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3<mask_1:6>)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:6>	7	30	6	ccc(C(F	7	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	ccc(C(F
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc<mask_1:7>cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:7>	10	33	7	(C(F)(F)F)	7	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc4nnnn4ccc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	4nnnn4c
<\|startoftext\|><L>C[C<mask_1:5>[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:5>	6	3	5	@@H]1C	5	C[C@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	@H]1C
<\|startoftext\|><L>C[C@@H<mask_1:6>](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:6>	8	6	6	]1C[C@@H	6	C[C@@H]1C[C@](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	]1C[C@
<\|startoftext\|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])<mask_1:3>C(=O)O1<mask_1:3>	4	59	3	CC2)	3	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])C2)C(=O)O1	C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1	C2)
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)C(=<mask_1:5>c1cccc(CN2CCOCC2)c1<mask_1:5>	4	23	5	O)NC	5	COc1ccccc1O[C@@H](C)C(=O)NCCc1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	O)NCC
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)C(=O)<mask_1:3>ccc(CN2CCOCC2)c1<mask_1:3>	5	25	3	NCc1c	3	COc1ccccc1O[C@@H](C)C(=O)c1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	c1c
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)C(=O)NCc1ccc<mask_1:4>N2CCOCC2)c1<mask_1:4>	3	32	4	c(C	4	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CCN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	c(CC
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)C(=O<mask_1:4>c1cccc(CN2CCOCC2)c1<mask_1:4>	3	24	4	)NC	4	COc1ccccc1O[C@@H](C)C(=O)NCCc1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	)NCC
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)<mask_1:4>Cc1cccc(CN2CCOCC2)c1<mask_1:4>	6	20	4	C(=O)N	4	COc1ccccc1O[C@@H](C)C(O)Cc1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	C(O)
<\|startoftext\|><L>COc1<mask_1:6>cc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1<mask_1:6>	3	4	6	ccc	6	COc1ccc(C)cc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	ccc(C)
<\|startoftext\|><L>COc1ccccc1O[C@@H]<mask_1:6>C)C(=O)NCc1cccc(CN2CCOCC2)c1<mask_1:6>	1	17	6	(	6	COc1ccccc1O[C@@H](CC(C)C)C(=O)NCc1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	(CC(C)
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)C(=<mask_1:4>cccc(CN2CCOCC2)c1<mask_1:4>	6	23	4	O)NCc1	4	COc1ccccc1O[C@@H](C)C(=O)c1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	O)c1
<\|startoftext\|><L>CO<mask_1:2>1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1<mask_1:2>	1	2	2	c	2	COCc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	Cc
<\|startoftext\|><L>COc1ccccc1O[C@@H](C)C(=O)NCc<mask_1:6>ccc(CN2CCOCC2)c1<mask_1:6>	2	28	6	1c	6	COc1ccccc1O[C@@H](C)C(=O)NCc1c(Cl)ccc(CN2CCOCC2)c1	COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1	1c(Cl)
<\|startoftext\|><L>C[C@@H]1OCC<mask_1:3>1C(=O)NCCCc1nc2ccccc2n1C<mask_1:3>	6	11	3	[C@@H]	3	C[C@@H]1OCCCCN1C(=O)NCCCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	CCN
<\|startoftext\|><L>C[C@@<mask_1:4>OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:4>	3	5	4	H]1	4	C[C@@H]1COCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	H]1C
<\|startoftext\|><L>C[C@@H]1OCC[C@@H]1C(=O<mask_1:3>1nc2ccccc2n1C<mask_1:3>	6	22	3	)NCCCc	3	C[C@@H]1OCC[C@@H]1C(=O)Nc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	)Nc
<\|startoftext\|><L>C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n<mask_1:5>C<mask_1:5>	1	39	5	1	5	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C(C)C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	1C(C)
<\|startoftext\|><L>C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n<mask_1:4>C<mask_1:4>	1	39	4	1	4	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1CCOC	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	1CCO
<\|startoftext\|><L>C[C@@H]1OCC[C@@H]1C(=O)N<mask_1:3>CCc1nc2ccccc2n1C<mask_1:3>	1	24	3	C	3	C[C@@H]1OCC[C@@H]1C(=O)N(C)CCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	(C)
<\|startoftext\|><L>C[C@@H]1O<mask_1:1>[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:1>	2	9	1	CC	1	C[C@@H]1OC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	C
<\|startoftext\|><L>C[C@@H]<mask_1:5>CC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:5>	2	7	5	1O	5	C[C@@H]1CN=CCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	1CN=C
<\|startoftext\|><L>C[C@@H]1OCC<mask_1:2>1C(=O)NCCCc1nc2ccccc2n1C<mask_1:2>	6	11	2	[C@@H]	2	C[C@@H]1OCCCN1C(=O)NCCCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	CN
<\|startoftext\|><L>C[C@@H]1OC<mask_1:4>C[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:4>	0	10	4		4	C[C@@H]1OC(=O)C[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C	(=O)
<\|startoftext\|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@<mask_1:6>)n(C)n1<mask_1:6>	8	45	6	H]2CCCO2	6	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CC2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	H]2CC2
<\|startoftext\|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)<mask_1:3>O4)C[C@H]2CCCO2)n(C)n1<mask_1:3>	4	34	3	C)OC	3	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	C)O
<\|startoftext\|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO<mask_1:5>)n(C)n1<mask_1:5>	1	52	5	2	6	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)c(=O)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	2)c(=O
<\|startoftext\|><L>Cc1cc(C(=O)<mask_1:9>cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:9>	5	11	9	N(Cc2	9	Cc1cc(C(=O)N(C(=O)c2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	N(C(=O)c2
<\|startoftext\|><L>Cc1cc(C(=O<mask_1:6>)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:6>	0	10	6		6	Cc1cc(C(=O)CC(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	)CC(=O
<\|startoftext\|><L>C<mask_1:1>c1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:1>	0	1	1		1	CCc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	C
<\|startoftext\|><L>Cc1cc(C(=<mask_1:6>)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:6>	1	9	6	O	6	Cc1cc(C(=O)C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	O)C(=O
<\|startoftext\|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C<mask_1:5>C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:5>	1	33	5	)	5	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	)C(C)
<\|startoftext\|><L>Cc1cc(C<mask_1:2>(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:2>	5	7	2	(=O)N	2	Cc1cc(CCN(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	CN
<\|startoftext\|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)<mask_1:3>[C@H]2CCCO2)n(C)n1<mask_1:3>	6	36	3	OCO4)C	3	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)O4)[C@H]2CCCO2)n(C)n1	Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1	O4)
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)<mask_1:5>)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1<mask_1:5>	3	16	5	(=O	5	Cc1nn(C)cc1S(=O)CC(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	CC(=O
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2<mask_1:8>2[C@@H](C(F)(F)F)C[C@H]1C1CC1<mask_1:8>	9	24	8	c(C#N)cnn	8	Cc1nn(C)cc1S(=O)(=O)N1c2cc(F)ccc2[C@@H](C(F)(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	cc(F)ccc
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]<mask_1:2>C1CC1<mask_1:2>	1	56	2	1	2	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1CC1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	1C
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@<mask_1:4>F)(F)F)C[C@H]1C1CC1<mask_1:4>	6	37	4	@H](C(	4	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@](C(F)(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	](C(
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H]<mask_1:3>(F)F)C[C@H]1C1CC1<mask_1:3>	5	40	3	(C(F)	3	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](CC(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	(CC
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H]<mask_1:6>)(F)F)C[C@H]1C1CC1<mask_1:6>	4	40	6	(C(F	6	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](CCC(F)(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	(CCC(F
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C<mask_1:1>(F)F)C[C@H]1C1CC1<mask_1:1>	3	42	1	(F)	1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](CC(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	C
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)<mask_1:5>C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1<mask_1:5>	6	20	5	N1c2c(	5	Cc1nn(C)cc1S(=O)(=O)N1c2(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	N1c2(
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H]<mask_1:8>(F)F)C[C@H]1C1CC1<mask_1:8>	5	40	8	(C(F)	8	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(=O)OC(F)F)C[C@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	(C(=O)OC
<\|startoftext\|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)<mask_1:9>]1C1CC1<mask_1:9>	7	48	9	F)C[C@H	8	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@@H]1C1CC1	Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1	F)C[C@@H
<\|startoftext\|><L>Cc1ccc(CN2CCC(F)(F<mask_1:2>]3(CCN(c4ccccn4)C3)C2)s1<mask_1:2>	4	18	2	)[C@	3	Cc1ccc(CN2CCC(F)(F)[C]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	)[C
<\|startoftext\|><L>Cc1ccc(CN2CC<mask_1:3>F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:3>	2	12	3	C(	3	Cc1ccc(CN2CCCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	CC(
<\|startoftext\|><L>Cc1cc<mask_1:5>2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>	4	5	5	c(CN	5	Cc1ccc(CCN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	c(CCN
<\|startoftext\|><L>Cc1ccc(CN2CCC(F)(F)[C@]3<mask_1:1>N(c4ccccn4)C3)C2)s1<mask_1:1>	3	24	1	(CC	1	Cc1ccc(CN2CCC(F)(F)[C@]3(N(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	(
<\|startoftext\|><L>Cc1ccc(CN2CCC(F)(F)[C@]3(<mask_1:5>c4ccccn4)C3)C2)s1<mask_1:5>	4	25	5	CCN(	5	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(Cc4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	CCN(C
<\|startoftext\|><L>Cc1ccc(CN2CCC(<mask_1:5>C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>	6	14	5	F)(F)[	5	Cc1ccc(CN2CCC(=O)N[C@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	=O)N[
<\|startoftext\|><L>Cc1ccc(CN2CCC(F)(F)[<mask_1:4>3(CCN(c4ccccn4)C3)C2)s1<mask_1:4>	3	20	4	C@]	4	Cc1ccc(CN2CCC(F)(F)[C@@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	C@@]
<\|startoftext\|><L><mask_1:5>1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>	2	0	5	Cc	5	N#CCc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	N#CCc
<\|startoftext\|><L>Cc1ccc(CN2CCC(F)<mask_1:5>C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>	4	16	5	(F)[	5	Cc1ccc(CN2CCC(F)(F)C[C@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	(F)C[
<\|startoftext\|><L>Cc1ccc(CN2<mask_1:2>(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:2>	3	10	2	CCC	2	Cc1ccc(CN2CC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1	CC

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O<mask_1:4>)C(C)(C)c2ccccc2)CC1<mask_1:4>

0

23

4

Cn1nccc1C(=O)N1CCN(C(=O)N(C)C(C)(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

)N(C

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C<mask_1:5>)C(C)(C)c2ccccc2)CC1<mask_1:5>

3

20

5

(=O

5

Cn1nccc1C(=O)N1CCN(C(C)(C)C(C)(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

(C)(C

<|startoftext|><L>Cn1nc<mask_1:6>c1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1<mask_1:6>

1

5

6

c

6

Cn1nc(C#N)cc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

(C#N)c

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc<mask_1:5>)CC1<mask_1:5>

1

38

5

2

5

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)N(C)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

2)N(C

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C<mask_1:2>2ccccc2)CC1<mask_1:2>

5

27

2

)(C)c

2

Cn1nccc1C(=O)N1CCN(C(=O)C(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

)c

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(<mask_1:6>=O)C(C)(C)c2ccccc2)CC1<mask_1:6>

2

19

6

C(

6

Cn1nccc1C(=O)N1CCN(S(=O)(=O)C(C)(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

S(=O)(

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O<mask_1:3>(C)c2ccccc2)CC1<mask_1:3>

5

23

3

)C(C)

3

Cn1nccc1C(=O)N1CCN(C(=O)CN(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

)CN

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(<mask_1:3>(C)c2ccccc2)CC1<mask_1:3>

2

26

3

C)

3

Cn1nccc1C(=O)N1CCN(C(=O)C(C)N(C)c2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

C)N

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C)<mask_1:4>c2ccccc2)CC1<mask_1:4>

3

28

4

(C)

4

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)Cc2ccccc2)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

(C)C

<|startoftext|><L>Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2<mask_1:3>C1<mask_1:3>

2

39

3

)C

3

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2F)CC1

Cn1nccc1C(=O)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1

F)C

<|startoftext|><L>O=C(O)[C@H](CNC(<mask_1:8>)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:8>

2

16

8

=O

8

O=C(O)[C@H](CNC(=O)NC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

=O)NC(=O

<|startoftext|><L>O=C(O)[C@<mask_1:8>(CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:8>

2

9

8

H]

8

O=C(O)[C@@H](O)CN(CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

@H](O)CN

<|startoftext|><L>O=C(O)[C@H](CN<mask_1:3>@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:3>

7

14

3

C(=O)[C

3

O=C(O)[C@H](CNC[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

C[C

<|startoftext|><L>O=C(O)[C@H<mask_1:6>)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:6>

8

10

6

](CNC(=O

6

O=C(O)[C@H](CN(O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

](CN(O

<|startoftext|><L>O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]2<mask_1:8>C1<mask_1:8>

6

52

8

1)CC1C

8

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CCOC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

1)CC1CCO

<|startoftext|><L>O=C(O)[C@H](CNC(<mask_1:7>=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:7>

0

16

7

O=C(O)[C@H](CNC(=O)CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

=O)CNC(

<|startoftext|><L>O=C(O)[C@<mask_1:9>=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:9>

7

9

H](CNC(

9

O=C(O)[C@@H](CCNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

@H](CCNC(

<|startoftext|><L>O=C(O)[C@H](C<mask_1:3>)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:3>

5

13

3

NC(=O

3

O=C(O)[C@H](C(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

(=O

<|startoftext|><L>O=C(O)[C@<mask_1:9>O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:9>

8

9

H](CNC(=

9

O=C(O)[C@@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

@H](CNC(=

<|startoftext|><L>O=C<mask_1:3>](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1<mask_1:3>

7

3

(O)[C@H

3

O=C[S@](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

O=C(O)[C@H](CNC(=O)[C@@H]1[C@@H]2Cc3c(Cl)cccc3[C@H]21)CC1CC1

[S@

<|startoftext|><L>Cc1ccccc1-c1nnn(<mask_1:6>c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:6>

5

16

6

CCCn2

6

Cc1ccccc1-c1nnn(CCCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

CCCCn2

<|startoftext|><L>Cc1ccccc1-c1nnn(CC<mask_1:7>O)c3c(ncn3C)n(C)c2=O)n1<mask_1:7>

6

18

7

Cn2c(=

7

Cc1ccccc1-c1nnn(CCOc2c(C=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Oc2c(C=

<|startoftext|><L>Cc1ccccc1-c1nnn(CCCn2c(<mask_1:6>O)c3c(ncn3C)n(C)c2=O)n1<mask_1:6>

1

23

6

=

6

Cc1ccccc1-c1nnn(CCCn2c(=O)c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

=O)c(=

<|startoftext|><L>Cc1ccccc1-c1nnn(CC<mask_1:7>Cn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:7>

0

18

7

Cc1ccccc1-c1nnn(CC(=O)NCCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

(=O)NCC

<|startoftext|><L>Cc1ccccc1-c1nnn(<mask_1:5>CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:5>

1

16

5

C

5

Cc1ccccc1-c1nnn(C(=O)CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

C(=O)

<|startoftext|><L>Cc1ccccc1-c1nnn(C<mask_1:5>c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:5>

4

17

5

CCn2

5

Cc1ccccc1-c1nnn(CCCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

CCCn2

<|startoftext|><L>Cc1ccccc1-c1nnn(CCCn2c(=<mask_1:1>O)c3c(ncn3C)n(C)c2=O)n1<mask_1:1>

0

24

1

Cc1ccccc1-c1nnn(CCCn2c(=SO)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

S

<|startoftext|><L>Cc1ccccc1-c1nnn<mask_1:6>(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:6>

7

15

6

(CCCn2c

6

Cc1ccccc1-c1nnn(CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

(CCn2c

<|startoftext|><L>Cc1ccccc1<mask_1:3>1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:3>

2

9

3

-c

3

Cc1ccccc1OCc1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

OCc

<|startoftext|><L>Cc1ccccc1-c1nn<mask_1:3>Cn2c(=O)c3c(ncn3C)n(C)c2=O)n1<mask_1:3>

4

14

3

n(CC

3

Cc1ccccc1-c1nnn(CCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

Cc1ccccc1-c1nnn(CCCn2c(=O)c3c(ncn3C)n(C)c2=O)n1

n(C

<|startoftext|><L>C[C@@H](C(=O)NCCSCc1ccccc1C<mask_1:7>1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:7>

5

27

7

l)N(c

7

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(CCc1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

l)N(CCc

<|startoftext|><L>C[C@@H](C(=O)NCCSCc1cc<mask_1:4>cc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:4>

1

22

4

c

4

C[C@@H](C(=O)NCCSCc1cc(F)ccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

(F)c

<|startoftext|><L>C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(<mask_1:8>c2c(c1)OCCO2)S(C)(=O)=O<mask_1:8>

4

31

8

c1cc

8

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1cc(Cl)c2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

c1cc(Cl)

<|startoftext|><L>C[C@@<mask_1:7>(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:7>

2

5

7

H]

7

C[C@@H](CO)N(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

H](CO)N

<|startoftext|><L>C[C@@H<mask_1:7>C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:7>

2

6

7

](

7

C[C@@H](C(=O)C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

](C(=O)

<|startoftext|><L>C[C@@H](C<mask_1:4>CSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:4>

6

9

4

(=O)NC

4

C[C@@H](C(=O)CSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

(=O)

<|startoftext|><L>C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1<mask_1:2>OCCO2)S(C)(=O)=O<mask_1:2>

1

41

2

)

2

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)COCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

)C

<|startoftext|><L>C[C@@H](C(=O)NCCSCc1ccccc<mask_1:8>c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:8>

6

25

8

1Cl)N(

8

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(CCc1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

1Cl)N(CC

<|startoftext|><L>C[C@@H](C(=O)NCC<mask_1:3>ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:3>

4

16

3

SCc1

3

C[C@@H](C(=O)NCCOc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

Oc1

<|startoftext|><L>C[<mask_1:6>(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O<mask_1:6>

5

2

6

C@@H]

6

C[C@](C)(C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C[C@@H](C(=O)NCCSCc1ccccc1Cl)N(c1ccc2c(c1)OCCO2)S(C)(=O)=O

C@](C)

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O<mask_1:7>)CC2)C(=O)O1<mask_1:7>

2

56

7

-]

7

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC(O)CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

-])CC(O

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2C<mask_1:10>(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:10>

8

25

10

CN(c3ccc

10

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3nc(C)(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

CN(c3nc(C)

<|startoftext|><L>C[C@@H]<mask_1:7>C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:7>

1

7

1

7

C[C@@H]1C(=O)CC[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

1C(=O)C

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])C<mask_1:7>O1<mask_1:7>

8

60

7

C2)C(=O)

8

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

C2)C(=O)

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C<mask_1:3>c3[N+](=O)[O-])CC2)C(=O)O1<mask_1:3>

9

35

3

(F)(F)F)c

3

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(Cl)cc3[N+](=O)[O-])CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

l)c

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3<mask_1:6>)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:6>

7

30

6

ccc(C(F

7

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

ccc(C(F

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc<mask_1:7>cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:7>

10

33

7

(C(F)(F)F)

7

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc4nnnn4ccc3[N+](=O)[O-])CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

4nnnn4c

<|startoftext|><L>C[C<mask_1:5>[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:5>

6

3

5

@@H]1C

5

C[C@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

@H]1C

<|startoftext|><L>C[C@@H<mask_1:6>](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1<mask_1:6>

8

6

]1C[C@@H

6

C[C@@H]1C[C@](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

]1C[C@

<|startoftext|><L>C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])<mask_1:3>C(=O)O1<mask_1:3>

4

59

3

CC2)

3

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])C2)C(=O)O1

C[C@@H]1C[C@@H](OC(=O)C2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)C(=O)O1

C2)

<|startoftext|><L>COc1ccccc1O[C@@H](C)C(=<mask_1:5>c1cccc(CN2CCOCC2)c1<mask_1:5>

4

23

5

O)NC

5

COc1ccccc1O[C@@H](C)C(=O)NCCc1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

O)NCC

<|startoftext|><L>COc1ccccc1O[C@@H](C)C(=O)<mask_1:3>ccc(CN2CCOCC2)c1<mask_1:3>

5

25

3

NCc1c

3

COc1ccccc1O[C@@H](C)C(=O)c1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

c1c

<|startoftext|><L>COc1ccccc1O[C@@H](C)C(=O)NCc1ccc<mask_1:4>N2CCOCC2)c1<mask_1:4>

3

32

4

c(C

4

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CCN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

c(CC

<|startoftext|><L>COc1ccccc1O[C@@H](C)C(=O<mask_1:4>c1cccc(CN2CCOCC2)c1<mask_1:4>

3

24

4

)NC

4

COc1ccccc1O[C@@H](C)C(=O)NCCc1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

)NCC

<|startoftext|><L>COc1ccccc1O[C@@H](C)<mask_1:4>Cc1cccc(CN2CCOCC2)c1<mask_1:4>

6

20

4

C(=O)N

4

COc1ccccc1O[C@@H](C)C(O)Cc1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

C(O)

<|startoftext|><L>COc1<mask_1:6>cc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1<mask_1:6>

3

4

6

ccc

6

COc1ccc(C)cc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

ccc(C)

<|startoftext|><L>COc1ccccc1O[C@@H]<mask_1:6>C)C(=O)NCc1cccc(CN2CCOCC2)c1<mask_1:6>

1

17

6

(

6

COc1ccccc1O[C@@H](CC(C)C)C(=O)NCc1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

(CC(C)

<|startoftext|><L>COc1ccccc1O[C@@H](C)C(=<mask_1:4>cccc(CN2CCOCC2)c1<mask_1:4>

6

23

4

O)NCc1

4

COc1ccccc1O[C@@H](C)C(=O)c1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

O)c1

<|startoftext|><L>CO<mask_1:2>1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1<mask_1:2>

1

2

c

2

COCc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

Cc

<|startoftext|><L>COc1ccccc1O[C@@H](C)C(=O)NCc<mask_1:6>ccc(CN2CCOCC2)c1<mask_1:6>

2

28

6

1c

6

COc1ccccc1O[C@@H](C)C(=O)NCc1c(Cl)ccc(CN2CCOCC2)c1

COc1ccccc1O[C@@H](C)C(=O)NCc1cccc(CN2CCOCC2)c1

1c(Cl)

<|startoftext|><L>C[C@@H]1OCC<mask_1:3>1C(=O)NCCCc1nc2ccccc2n1C<mask_1:3>

6

11

3

[C@@H]

3

C[C@@H]1OCCCCN1C(=O)NCCCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

CCN

<|startoftext|><L>C[C@@<mask_1:4>OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:4>

3

5

4

H]1

4

C[C@@H]1COCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

H]1C

<|startoftext|><L>C[C@@H]1OCC[C@@H]1C(=O<mask_1:3>1nc2ccccc2n1C<mask_1:3>

6

22

3

)NCCCc

3

C[C@@H]1OCC[C@@H]1C(=O)Nc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

)Nc

<|startoftext|><L>C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n<mask_1:5>C<mask_1:5>

1

39

5

1

5

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C(C)C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

1C(C)

<|startoftext|><L>C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n<mask_1:4>C<mask_1:4>

1

39

4

1

4

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1CCOC

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

1CCO

<|startoftext|><L>C[C@@H]1OCC[C@@H]1C(=O)N<mask_1:3>CCc1nc2ccccc2n1C<mask_1:3>

1

24

3

C

3

C[C@@H]1OCC[C@@H]1C(=O)N(C)CCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

(C)

<|startoftext|><L>C[C@@H]1O<mask_1:1>[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:1>

2

9

1

CC

1

C[C@@H]1OC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

C

<|startoftext|><L>C[C@@H]<mask_1:5>CC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:5>

2

7

5

1O

5

C[C@@H]1CN=CCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

1CN=C

<|startoftext|><L>C[C@@H]1OCC<mask_1:2>1C(=O)NCCCc1nc2ccccc2n1C<mask_1:2>

6

11

2

[C@@H]

2

C[C@@H]1OCCCN1C(=O)NCCCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

CN

<|startoftext|><L>C[C@@H]1OC<mask_1:4>C[C@@H]1C(=O)NCCCc1nc2ccccc2n1C<mask_1:4>

0

10

4

C[C@@H]1OC(=O)C[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

C[C@@H]1OCC[C@@H]1C(=O)NCCCc1nc2ccccc2n1C

(=O)

<|startoftext|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@<mask_1:6>)n(C)n1<mask_1:6>

8

45

6

H]2CCCO2

6

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CC2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

H]2CC2

<|startoftext|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)<mask_1:3>O4)C[C@H]2CCCO2)n(C)n1<mask_1:3>

4

34

3

C)OC

3

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

C)O

<|startoftext|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO<mask_1:5>)n(C)n1<mask_1:5>

1

52

5

2

6

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)c(=O)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

2)c(=O

<|startoftext|><L>Cc1cc(C(=O)<mask_1:9>cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:9>

5

11

9

N(Cc2

9

Cc1cc(C(=O)N(C(=O)c2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

N(C(=O)c2

<|startoftext|><L>Cc1cc(C(=O<mask_1:6>)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:6>

0

10

6

Cc1cc(C(=O)CC(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

)CC(=O

<|startoftext|><L>C<mask_1:1>c1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:1>

0

1

CCc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

C

<|startoftext|><L>Cc1cc(C(=<mask_1:6>)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:6>

1

9

6

O

6

Cc1cc(C(=O)C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

O)C(=O

<|startoftext|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C<mask_1:5>C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:5>

1

33

5

)

5

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

)C(C)

<|startoftext|><L>Cc1cc(C<mask_1:2>(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1<mask_1:2>

5

7

2

(=O)N

2

Cc1cc(CCN(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

CN

<|startoftext|><L>Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)<mask_1:3>[C@H]2CCCO2)n(C)n1<mask_1:3>

6

36

3

OCO4)C

3

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)O4)[C@H]2CCCO2)n(C)n1

Cc1cc(C(=O)N(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)C[C@H]2CCCO2)n(C)n1

O4)

<|startoftext|><L>Cc1nn(C)cc1S(=O)<mask_1:5>)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1<mask_1:5>

3

16

5

(=O

5

Cc1nn(C)cc1S(=O)CC(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1

Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1

CC(=O

<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2<mask_1:8>2[C@@H](C(F)(F)F)C[C@H]1C1CC1<mask_1:8>

9

24

8

c(C#N)cnn

8

Cc1nn(C)cc1S(=O)(=O)N1c2cc(F)ccc2[C@@H](C(F)(F)F)C[C@H]1C1CC1

Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1

cc(F)ccc

<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]<mask_1:2>C1CC1<mask_1:2>

1

56

2

1

2

Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1CC1CC1

Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1

1C

<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@<mask_1:4>F)(F)F)C[C@H]1C1CC1<mask_1:4>

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37

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Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@](C(F)(F)F)C[C@H]1C1CC1

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<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H]<mask_1:3>(F)F)C[C@H]1C1CC1<mask_1:3>

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40

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Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](CC(F)F)C[C@H]1C1CC1

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<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H]<mask_1:6>)(F)F)C[C@H]1C1CC1<mask_1:6>

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Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](CCC(F)(F)F)C[C@H]1C1CC1

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<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C<mask_1:1>(F)F)C[C@H]1C1CC1<mask_1:1>

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<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)<mask_1:5>C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1<mask_1:5>

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Cc1nn(C)cc1S(=O)(=O)N1c2(C#N)cnn2[C@@H](C(F)(F)F)C[C@H]1C1CC1

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<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H]<mask_1:8>(F)F)C[C@H]1C1CC1<mask_1:8>

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<|startoftext|><L>Cc1nn(C)cc1S(=O)(=O)N1c2c(C#N)cnn2[C@@H](C(F)(F)<mask_1:9>]1C1CC1<mask_1:9>

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<|startoftext|><L>Cc1ccc(CN2CCC(F)(F<mask_1:2>]3(CCN(c4ccccn4)C3)C2)s1<mask_1:2>

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18

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<|startoftext|><L>Cc1ccc(CN2CC<mask_1:3>F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:3>

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<|startoftext|><L>Cc1cc<mask_1:5>2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>

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c(CN

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<|startoftext|><L>Cc1ccc(CN2CCC(F)(F)[C@]3<mask_1:1>N(c4ccccn4)C3)C2)s1<mask_1:1>

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24

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<|startoftext|><L>Cc1ccc(CN2CCC(F)(F)[C@]3(<mask_1:5>c4ccccn4)C3)C2)s1<mask_1:5>

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Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(Cc4ccccn4)C3)C2)s1

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<|startoftext|><L>Cc1ccc(CN2CCC(<mask_1:5>C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>

6

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Cc1ccc(CN2CCC(=O)N[C@]3(CCN(c4ccccn4)C3)C2)s1

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<|startoftext|><L>Cc1ccc(CN2CCC(F)(F)[<mask_1:4>3(CCN(c4ccccn4)C3)C2)s1<mask_1:4>

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20

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Cc1ccc(CN2CCC(F)(F)[C@@]3(CCN(c4ccccn4)C3)C2)s1

Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1

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<|startoftext|><L><mask_1:5>1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>

2

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<|startoftext|><L>Cc1ccc(CN2CCC(F)<mask_1:5>C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:5>

4

16

5

(F)[

5

Cc1ccc(CN2CCC(F)(F)C[C@]3(CCN(c4ccccn4)C3)C2)s1

Cc1ccc(CN2CCC(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1

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<|startoftext|><L>Cc1ccc(CN2<mask_1:2>(F)(F)[C@]3(CCN(c4ccccn4)C3)C2)s1<mask_1:2>

3

10

2

CCC

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