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stringlengths 49
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| first_mask_count
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| first_mask_gen_count
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stringlengths 0
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| first_mask_gen_count_real
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<|startoftext|><L>Cc1ccc([C@H]2/C(=C(<mask_1:9>c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:9> | 3 | 19 | 9 | \O) | 9 | Cc1ccc([C@H]2/C(=C(\O)C(=O)Nc3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | \O)C(=O)N |
<|startoftext|><L>Cc1ccc([C@H]2/C(=C(\O<mask_1:5>(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:5> | 6 | 21 | 5 | )c3ccc | 5 | Cc1ccc([C@H]2/C(=C(\O)c3sc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | )c3sc |
<|startoftext|><L>Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CC<mask_1:1>COCC2)o1<mask_1:1> | 4 | 49 | 1 | CN2C | 1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CC2COCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | 2 |
<|startoftext|><L>Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCC<mask_1:4>2CCOCC2)o1<mask_1:4> | 1 | 50 | 4 | N | 4 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCCCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | CCCN |
<|startoftext|><L>Cc1ccc([C@H]2/C(=C<mask_1:1>cc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:1> | 7 | 18 | 1 | (\O)c3c | 1 | Cc1ccc([C@H]2/C(=C3cc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | 3 |
<|startoftext|><L>Cc1ccc([C@H]2/C(<mask_1:7>C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:7> | 1 | 16 | 7 | = | 7 | Cc1ccc([C@H]2/C(=C(\O)\C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | =C(\O)\ |
<|startoftext|><L>Cc1cc<mask_1:5>c([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:5> | 0 | 5 | 5 | 5 | Cc1cc(=O)cc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | (=O)c |
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<|startoftext|><L>Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc<mask_1:8>C(=O)N2CCCN2CCOCC2)o1<mask_1:8> | 7 | 33 | 8 | 3)C(=O) | 8 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)NC(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | 3)C(=O)N |
<|startoftext|><L>Cc1ccc([C@H]2/C(=C(\O)c3c<mask_1:8>cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:8> | 6 | 25 | 8 | cc(Cl) | 8 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(OCCO)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | cc(OCCO) |
<|startoftext|><L>Cc1ccc<mask_1:7>C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1<mask_1:7> | 8 | 6 | 7 | ([C@H]2/ | 7 | Cc1ccc([C@H]2C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | Cc1ccc([C@H]2/C(=C(\O)c3ccc(Cl)cc3)C(=O)C(=O)N2CCCN2CCOCC2)o1 | ([C@H]2 |
<|startoftext|><L>CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(<mask_1:2>21<mask_1:2> | 4 | 33 | 2 | OC)c | 2 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(O)21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | O) |
<|startoftext|><L>CCn1/c(=N/C(=O)<mask_1:1>C(C)C)sc2c(OC)ccc(OC)c21<mask_1:1> | 0 | 15 | 1 | 1 | CCn1/c(=N/C(=O)CC(C)C)sc2c(OC)ccc(OC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | C |
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<|startoftext|><L>CC<mask_1:2>n1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21<mask_1:2> | 0 | 2 | 2 | 2 | CCCCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | CC |
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<|startoftext|><L>CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(<mask_1:1>)c21<mask_1:1> | 2 | 33 | 1 | OC | 1 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(O)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | O |
<|startoftext|><L>CCn1/c(=N/C(=O)C(C)C)sc2c(<mask_1:3>OC)ccc(OC)c21<mask_1:3> | 0 | 26 | 3 | 3 | CCn1/c(=N/C(=O)C(C)C)sc2c(OCCOC)ccc(OC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | OCC |
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<|startoftext|><L>CCn1/c(=N/C(=O)C(C)C)sc2<mask_1:1>ccc(OC)c21<mask_1:1> | 5 | 24 | 1 | c(OC) | 1 | CCn1/c(=N/C(=O)C(C)C)sc2cccc(OC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | c |
<|startoftext|><L><mask_1:3>CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21<mask_1:3> | 0 | 0 | 3 | 3 | C=CCCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | C=C |
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<|startoftext|><L>C<mask_1:3>1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21<mask_1:3> | 2 | 1 | 3 | Cn | 3 | CCCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | CCn |
<|startoftext|><L>CCn1/c(=N/C(=O)C(C)C)sc2c(OC)<mask_1:5>OC)c21<mask_1:5> | 4 | 29 | 5 | ccc( | 5 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(COC)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | ccc(C |
<|startoftext|><L>CCn1/c(=N/C(=O)C(C)C)sc2c(OC)<mask_1:2>C)c21<mask_1:2> | 5 | 29 | 2 | ccc(O | 2 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)c(C)c21 | CCn1/c(=N/C(=O)C(C)C)sc2c(OC)ccc(OC)c21 | c( |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)<mask_1:8>CSc1nc2ccccc2c(=O)n1C1CCCC1<mask_1:8> | 5 | 26 | 8 | C(=O) | 8 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)NCCCSc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | C(=O)NCC |
<|startoftext|><L>C[C@@H](C1CC1)N(CC<mask_1:6>F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1<mask_1:6> | 1 | 18 | 6 | ( | 6 | C[C@@H](C1CC1)N(CC(=O)C(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | (=O)C( |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C<mask_1:1>1nc2ccccc2c(=O)n1C1CCCC1<mask_1:1> | 7 | 27 | 1 | (=O)CSc | 1 | C[C@@H](C1CC1)N(CC(F)(F)F)Cc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | c |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C<mask_1:4>nc2ccccc2c(=O)n1C1CCCC1<mask_1:4> | 8 | 27 | 4 | (=O)CSc1 | 4 | C[C@@H](C1CC1)N(CC(F)(F)F)CCSc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | CSc1 |
<|startoftext|><L>C[C@@H](C<mask_1:8>CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1<mask_1:8> | 7 | 9 | 8 | 1CC1)N( | 8 | C[C@@H](CNC(=O)NCCC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | NC(=O)NC |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)<mask_1:7>C1CCCC1<mask_1:7> | 2 | 49 | 7 | n1 | 7 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C(=O)C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | n1C(=O) |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C<mask_1:3>CCC1<mask_1:3> | 2 | 52 | 3 | 1C | 3 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | 1CC |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C<mask_1:7>O)CSc1nc2ccccc2c(=O)n1C1CCCC1<mask_1:7> | 2 | 27 | 7 | (= | 7 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | (=O)C(= |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CC<mask_1:6>1<mask_1:6> | 2 | 55 | 6 | CC | 6 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCN(C)CC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | N(C)CC |
<|startoftext|><L>C[C@@H](C1CC1)N(CC(F)(F)F)C(<mask_1:5>1nc2ccccc2c(=O)n1C1CCCC1<mask_1:5> | 6 | 28 | 5 | =O)CSc | 5 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)Cc1nc2ccccc2c(=O)n1C1CCCC1 | C[C@@H](C1CC1)N(CC(F)(F)F)C(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 | =O)Cc |
<|startoftext|><L>N[C@H]1CN<mask_1:4>CCCn2cnnn2)C[C@@H]1C1CC1<mask_1:4> | 1 | 9 | 4 | ( | 4 | N[C@H]1CN(CCOCCCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | (CCO |
<|startoftext|><L>N[C@H]1CN<mask_1:1>n2cnnn2)C[C@@H]1C1CC1<mask_1:1> | 4 | 9 | 1 | (CCC | 1 | N[C@H]1CN(n2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | ( |
<|startoftext|><L>N[C@H]1CN(CCC<mask_1:5>2cnnn2)C[C@@H]1C1CC1<mask_1:5> | 1 | 13 | 5 | n | 5 | N[C@H]1CN(CCCCOCCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | COCCn |
<|startoftext|><L>N[C@H]1CN(CCCn2cnnn2)<mask_1:2>[C@@H]1C1CC1<mask_1:2> | 1 | 21 | 2 | C | 2 | N[C@H]1CN(CCCn2cnnn2)CC[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | CC |
<|startoftext|><L>N[C@H]1CN<mask_1:3>CCCn2cnnn2)C[C@@H]1C1CC1<mask_1:3> | 1 | 9 | 3 | ( | 3 | N[C@H]1CN(CCCCCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | (CC |
<|startoftext|><L>N[C@H]1CN(CCC<mask_1:4>nnn2)C[C@@H]1C1CC1<mask_1:4> | 3 | 13 | 4 | n2c | 4 | N[C@H]1CN(CCCCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | Cn2c |
<|startoftext|><L>N[C@H]1<mask_1:4>N(CCCn2cnnn2)C[C@@H]1C1CC1<mask_1:4> | 1 | 7 | 4 | C | 4 | N[C@H]1CCCCN(CCCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | CCCC |
<|startoftext|><L>N[C@H]1CN<mask_1:3>CCCn2cnnn2)C[C@@H]1C1CC1<mask_1:3> | 1 | 9 | 3 | ( | 3 | N[C@H]1CN(CCCCCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | (CC |
<|startoftext|><L>N[C@H]1CN<mask_1:4>2cnnn2)C[C@@H]1C1CC1<mask_1:4> | 5 | 9 | 4 | (CCCn | 4 | N[C@H]1CN(CCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | (CCn |
<|startoftext|><L>N[C@H]1CN(CC<mask_1:3>nnn2)C[C@@H]1C1CC1<mask_1:3> | 4 | 12 | 3 | Cn2c | 3 | N[C@H]1CN(CCn2cnnn2)C[C@@H]1C1CC1 | N[C@H]1CN(CCCn2cnnn2)C[C@@H]1C1CC1 | n2c |
<|startoftext|><L>Cc1cc(C(=O)N2CC[<mask_1:6>(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C<mask_1:6> | 5 | 16 | 6 | C@@]3 | 6 | Cc1cc(C(=O)N2CC[C@H]3C(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | C@H]3C |
<|startoftext|><L>Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2<mask_1:2>-c2ccco2)CO3)nn1C<mask_1:2> | 0 | 34 | 2 | 2 | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2CO-c2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | CO |
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<|startoftext|><L>Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nn<mask_1:7>cco2)CO3)nn1C<mask_1:7> | 6 | 32 | 7 | c2-c2c | 7 | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2CCc2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | c2CCc2c |
<|startoftext|><L>Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccc<mask_1:4>CO3)nn1C<mask_1:4> | 3 | 40 | 4 | o2) | 4 | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccccn2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | cn2) |
<|startoftext|><L>Cc1cc(C(=O<mask_1:7>2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C<mask_1:7> | 2 | 10 | 7 | )N | 7 | Cc1cc(C(=O)N[C@H]2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | )N[C@H] |
<|startoftext|><L>Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2cc<mask_1:5>CO3)nn1C<mask_1:5> | 4 | 39 | 5 | co2) | 5 | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2cccnc2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | cnc2) |
<|startoftext|><L>Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-<mask_1:7>co2)CO3)nn1C<mask_1:7> | 4 | 35 | 7 | c2cc | 7 | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2cc(C)co2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | c2cc(C) |
<|startoftext|><L>Cc1cc(<mask_1:4>O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C<mask_1:4> | 3 | 6 | 4 | C(= | 4 | Cc1cc(NC(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | NC(= |
<|startoftext|><L>Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c<mask_1:3>nnc2-c2ccco2)CO3)nn1C<mask_1:3> | 1 | 29 | 3 | ( | 3 | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnnnc2-c2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | (nn |
<|startoftext|><L>Cc1cc(C(=O<mask_1:4>N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C<mask_1:4> | 1 | 10 | 4 | ) | 4 | Cc1cc(C(=O)NCCN2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | Cc1cc(C(=O)N2CC[C@@]3(C2)Cn2c(nnc2-c2ccco2)CO3)nn1C | )NCC |
<|startoftext|><L><mask_1:5>cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1<mask_1:5> | 3 | 0 | 5 | Cc1 | 5 | CCCc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | CCCc1 |
<|startoftext|><L>Cc1cc(C[<mask_1:3>](=O)[C@@H](C)C(=O)NC2CCCC2)no1<mask_1:3> | 2 | 8 | 3 | S@ | 3 | Cc1cc(C[S@@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | S@@ |
<|startoftext|><L>Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC<mask_1:2>)no1<mask_1:2> | 6 | 31 | 2 | 2CCCC2 | 2 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NCCF)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | CF |
<|startoftext|><L>Cc1cc(C[S@](=<mask_1:6>O)[C@@H](C)C(=O)NC2CCCC2)no1<mask_1:6> | 0 | 13 | 6 | 6 | Cc1cc(C[S@](=O)CC(=O)[C@@H](C)C(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | O)CC(= |
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<|startoftext|><L>Cc1cc(C[S@](=O)[C@<mask_1:5>C(=O)NC2CCCC2)no1<mask_1:5> | 6 | 18 | 5 | @H](C) | 5 | Cc1cc(C[S@](=O)[C@H](C)C(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | H](C) |
<|startoftext|><L>Cc1cc(C[S@](=O)[C@<mask_1:3>)C(=O)NC2CCCC2)no1<mask_1:3> | 5 | 18 | 3 | @H](C | 3 | Cc1cc(C[S@](=O)[C@](C)C(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | ](C |
<|startoftext|><L>Cc1cc(C[S@](=O)[C@@H](C)C(=<mask_1:4>CCC2)no1<mask_1:4> | 6 | 27 | 4 | O)NC2C | 4 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)N2CCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | O)N2 |
<|startoftext|><L>Cc1cc(C[S@](=O)[C<mask_1:6>C)C(=O)NC2CCCC2)no1<mask_1:6> | 5 | 17 | 6 | @@H]( | 6 | Cc1cc(C[S@](=O)[C@@H](CC)C(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | @@H](C |
<|startoftext|><L>Cc1cc(C[S@](=O)[C@@H](<mask_1:6>=O)NC2CCCC2)no1<mask_1:6> | 4 | 22 | 6 | C)C( | 6 | Cc1cc(C[S@](=O)[C@@H](C)CCC(=O)NC2CCCC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | C)CCC( |
<|startoftext|><L>Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2<mask_1:4>no1<mask_1:4> | 6 | 32 | 4 | CCCC2) | 4 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CC2)no1 | Cc1cc(C[S@](=O)[C@@H](C)C(=O)NC2CCCC2)no1 | CC2) |
<|startoftext|><L>C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C<mask_1:5>12<mask_1:5> | 10 | 56 | 5 | (F)(F)F)cn | 4 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(Cl)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | l)cn |
<|startoftext|><L>C[C@H]1[C@<mask_1:8>C[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:8> | 7 | 10 | 8 | H](C)CC | 8 | C[C@H]1[C@H](C)CCCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | H](C)CCC |
<|startoftext|><L><mask_1:4>@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:4> | 3 | 0 | 4 | C[C | 4 | C[C@@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@ |
<|startoftext|><L>C[C@H]1[C@H](C)<mask_1:3>1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:3> | 9 | 15 | 3 | CCC[C@@H] | 3 | C[C@H]1[C@H](C)CCC1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | CCC |
<|startoftext|><L>C[C@H]1[C@H](C)CCC[C@@H]<mask_1:7>O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:7> | 5 | 24 | 7 | 1NC(= | 8 | C[C@H]1[C@H](C)CCC[C@@H]1N(C)C(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | 1N(C)C(= |
<|startoftext|><L>C[C@H]1[C@H](C)CCC<mask_1:5>C(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:5> | 8 | 18 | 5 | [C@@H]1N | 5 | C[C@H]1[C@H](C)CCC[CH]1C(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | [CH]1 |
<|startoftext|><L>C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc<mask_1:8>Cl)cc(C(F)(F)F)cn12<mask_1:8> | 7 | 42 | 8 | 1nnc2c( | 8 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(CCl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | 1nnc2c(C |
<|startoftext|><L>C[C@H]1[C@H](C)CCC[C<mask_1:9>=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:9> | 8 | 20 | 9 | @@H]1NC( | 9 | C[C@H]1[C@H](C)CCC[C@@H]1CNC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | @@H]1CNC( |
<|startoftext|><L>C[C@<mask_1:8>H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:8> | 0 | 4 | 8 | 8 | C[C@H](O)[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | H](O)[C@ |
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<|startoftext|><L>C[C@H]1[C<mask_1:2>CC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12<mask_1:2> | 7 | 9 | 2 | @H](C)C | 2 | C[C@H]1[CH]CC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | C[C@H]1[C@H](C)CCC[C@@H]1NC(=O)[C@@H](C)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 | H] |
<|startoftext|><L>CCn1cc(CNc2cn(CC<mask_1:4>)C)nc2C)cn1<mask_1:4> | 2 | 16 | 4 | (C | 4 | CCn1cc(CNc2cn(CCNC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | NC(C |
<|startoftext|><L>CCn1cc(C<mask_1:4>c2cn(CC(C)C)nc2C)cn1<mask_1:4> | 1 | 8 | 4 | N | 4 | CCn1cc(C(=O)c2cn(CC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | (=O) |
<|startoftext|><L>CCn1cc(CNc2c<mask_1:4>C(C)C)nc2C)cn1<mask_1:4> | 3 | 12 | 4 | n(C | 4 | CCn1cc(CNc2cnc(NC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | nc(N |
<|startoftext|><L>CCn1cc(CNc2cn(CC(C)C)nc<mask_1:4>cn1<mask_1:4> | 3 | 23 | 4 | 2C) | 4 | CCn1cc(CNc2cn(CC(C)C)nc2OC)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | 2OC) |
<|startoftext|><L>CCn1cc(C<mask_1:4>cn(CC(C)C)nc2C)cn1<mask_1:4> | 3 | 8 | 4 | Nc2 | 4 | CCn1cc(CNCc2cn(CC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | NCc2 |
<|startoftext|><L>CCn1cc(CNc2cn(CC(C)C)nc2C<mask_1:1>)cn1<mask_1:1> | 0 | 25 | 1 | 1 | CCn1cc(CNc2cn(CC(C)C)nc2Cl)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | l |
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<|startoftext|><L>CCn1cc(C<mask_1:2>c2cn(CC(C)C)nc2C)cn1<mask_1:2> | 1 | 8 | 2 | N | 2 | CCn1cc(CNCc2cn(CC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | NC |
<|startoftext|><L><mask_1:3>n1cc(CNc2cn(CC(C)C)nc2C)cn1<mask_1:3> | 2 | 0 | 3 | CC | 3 | CCCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | CCC |
<|startoftext|><L>CCn1cc(CN<mask_1:1>n(CC(C)C)nc2C)cn1<mask_1:1> | 3 | 9 | 1 | c2c | 1 | CCn1cc(CN2n(CC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | 2 |
<|startoftext|><L>CCn1cc(CNc2cn(CC(C)C)nc2<mask_1:3>1<mask_1:3> | 4 | 24 | 3 | C)cn | 4 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | CCn1cc(CNc2cn(CC(C)C)nc2C)cn1 | C)cn |
<|startoftext|><L>CC(C)C[C<mask_1:2>C(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O<mask_1:2> | 6 | 8 | 2 | @@H]1N | 2 | CC(C)C[C]1C(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | ]1 |
<|startoftext|><L>CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2<mask_1:7>(F)cc2)C1=O<mask_1:7> | 3 | 33 | 7 | ccc | 7 | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2cc(Cl)c(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | cc(Cl)c |
<|startoftext|><L>CC(C)<mask_1:6>C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O<mask_1:6> | 0 | 5 | 6 | 6 | CC(C)(C)SCCC[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | (C)SCC |
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<|startoftext|><L>CC(C)C[C@@H]1NC(=O)<mask_1:7>@H](O)c2ccc(F)cc2)C1=O<mask_1:7> | 6 | 19 | 7 | N(C[C@ | 7 | CC(C)C[C@@H]1NC(=O)N(CC[C@@H](O)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | N(CC[C@ |
<|startoftext|><L>CC(C)C[C@@H]1NC(=O)N(C<mask_1:1>[C@@H](O)c2ccc(F)cc2)C1=O<mask_1:1> | 0 | 22 | 1 | 1 | CC(C)C[C@@H]1NC(=O)N(CC[C@@H](O)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | C |
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<|startoftext|><L>CC(C)C[C@@H]1NC(=O)N(C[<mask_1:5>)c2ccc(F)cc2)C1=O<mask_1:5> | 7 | 23 | 5 | C@@H](O | 5 | CC(C)C[C@@H]1NC(=O)N(C[C@](C)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | C@](C |
<|startoftext|><L><mask_1:6>C(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O<mask_1:6> | 1 | 0 | 6 | C | 6 | CC(C)=C(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | CC(C)= |
<|startoftext|><L>CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2cc<mask_1:6>)cc2)C1=O<mask_1:6> | 3 | 35 | 6 | c(F | 6 | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(C(F))cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | c(C(F) |
<|startoftext|><L>CC(C)C[C@@H]1NC(=O)N(C[C@@H]<mask_1:1>cc(F)cc2)C1=O<mask_1:1> | 6 | 28 | 1 | (O)c2c | 1 | CC(C)C[C@@H]1NC(=O)N(C[C@@H]2cc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | 2 |
<|startoftext|><L>CC(C)C[C@@H]1NC(=O)N(C[C@@H](<mask_1:3>)c2ccc(F)cc2)C1=O<mask_1:3> | 1 | 29 | 3 | O | 3 | CC(C)C[C@@H]1NC(=O)N(C[C@@H](C#N)c2ccc(F)cc2)C1=O | CC(C)C[C@@H]1NC(=O)N(C[C@@H](O)c2ccc(F)cc2)C1=O | C#N |
<|startoftext|><L>CSc1nccnc1CN(C(=O)[C@H](C)<mask_1:2>N)C1CC1<mask_1:2> | 0 | 26 | 2 | 2 | CSc1nccnc1CN(C(=O)[C@H](C)C#N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | C# |
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<|startoftext|><L>CSc1nccnc1CN(C(<mask_1:3>)[C@H](C)N)C1CC1<mask_1:3> | 2 | 15 | 3 | =O | 3 | CSc1nccnc1CN(C(C#N)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | C#N |
<|startoftext|><L>CSc1nccnc1CN<mask_1:4>=O)[C@H](C)N)C1CC1<mask_1:4> | 3 | 12 | 4 | (C( | 4 | CSc1nccnc1CN(CC(=O)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | (CC( |
<|startoftext|><L><mask_1:2>1nccnc1CN(C(=O)[C@H](C)N)C1CC1<mask_1:2> | 3 | 0 | 2 | CSc | 2 | Cc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | Cc |
<|startoftext|><L>CSc1nccnc1<mask_1:4>N(C(=O)[C@H](C)N)C1CC1<mask_1:4> | 1 | 10 | 4 | C | 4 | CSc1nccnc1N(C)N(C(=O)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | N(C) |
<|startoftext|><L>CSc1nccnc1CN(C(=O)[<mask_1:2>](C)N)C1CC1<mask_1:2> | 3 | 19 | 2 | C@H | 2 | CSc1nccnc1CN(C(=O)[C@](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | C@ |
<|startoftext|><L>CSc1<mask_1:4>cnc1CN(C(=O)[C@H](C)N)C1CC1<mask_1:4> | 2 | 4 | 4 | nc | 4 | CSc1[nH]cnc1CN(C(=O)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | [nH] |
<|startoftext|><L>C<mask_1:1>Sc1nccnc1CN(C(=O)[C@H](C)N)C1CC1<mask_1:1> | 0 | 1 | 1 | 1 | CCSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | C |
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<|startoftext|><L>CSc1nccnc1C<mask_1:4>(=O)[C@H](C)N)C1CC1<mask_1:4> | 3 | 11 | 4 | N(C | 4 | CSc1nccnc1CCN(C(=O)[C@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | CN(C |
<|startoftext|><L>CSc1nccnc1CN(C(=O)[C<mask_1:1>@H](C)N)C1CC1<mask_1:1> | 0 | 20 | 1 | 1 | CSc1nccnc1CN(C(=O)[C@@H](C)N)C1CC1 | CSc1nccnc1CN(C(=O)[C@H](C)N)C1CC1 | @ |