Long-term cognitive outcomes after pediatric stroke. 
This study assessed neurocognitive and neurologic outcomes of children with neonatal and childhood strokes.  Twenty-one children with neonatal (mean age, 6.86 years) and 10 children with childhood (mean age, 8.21 years) strokes, identified via the Estonian Pediatric Stroke Database (1995-2006), participated.  A developmental neuropsychologic assessment was used for neurocognitive outcomes, and the Paediatric Stroke Outcome Measure for neurologic outcomes.  Neuromotor impairment was evident in 62% of children with neonatal strokes, and in 70% of children with childhood strokes.  Compared with control subjects, children with strokes exhibited worse attention, language, memory, and sensorimotor functions.  The sensorimotor domain comprised the most impaired neurocognitive area, whereas executive functions remained intact in both stroke groups.  A well-preserved executive function may account for the normal range of intelligence in children with strokes.  More severe impairment in neurocognitive skills was evident after neonatal strokes, and the visuospatial domain was more impaired than in children from the childhood group.  Prognoses were worse after left hemisphere strokes associated with epilepsy.  Our results on emerging neurocognitive deficits in several areas underline the importance of neuropsychologic testing and the follow-up of children with pediatric strokes.