Travoprost in children: adverse effects and intraocular pressure response. 
Because of the limited ability to perform controlled, randomized studies in children, the safety and effectiveness of topical medications in pediatric glaucoma is sometimes difficult to determine.  Although travoprost has been commercially available since 2001, there are no published reports on its use in children.  This retrospective study found travoprost to have minimal adverse events in children and to reduce IOP in select cases of pediatric glaucoma.