The assessment of bioequivalence in a two-period cross-over design: development of a simple BASIC program. 
The complete algorithms needed in the calculation of confidence intervals on the basis of observations from a two-way cross-over bioequivalence trial are described.  They do not contain assumptions as to the expected sampling distribution or possible period effects.  The algorithms were used in a BASIC program, which was developed subsequently.  Its validity is demonstrated here with a set of literature data.  The program is available from the authors upon request.