DTP and DTP-inactivated polio vaccines: comparison of adverse reactions and IGG, IGM and IGA antibody responses to DTP. 
Adverse reactions and anti-DTP antibody responses were compared between DTP- or DTP-inactivated-polio-vaccinated children.  The material consisted of 380 children whose adverse reactions were registered by detailed questionnaires given to the parents.  IgG-, IgM- and IgA-anti-DTP antibodies of 42 children were quantified using enzyme-linked immunosorbent assay (ELISA).  Fever, restlessness and local reactions were the most frequent adverse reactions observed.  DTP-polio vaccine induced significantly more restlessness than DTP.  This was the only significant difference in adverse reactions between the vaccines.  An enhancement of IgG-anti-DTP antibody responses at the age of 6 months was observed in the DTP-polio group.  The enhancement was transient in antitoxin responses but still present in pertussis antibodies at 8 months of age.  Very low and mostly undetectable levels of IgM- and IgA-anti-DTP antibodies were observed in both groups.