Validation of the Amharic version of the Pelvic Organ Prolapse Symptom Score (POP-SS). 
We aimed to translate and culturally adapt the Pelvic Organ Prolapse Symptom Score (POP-SS) into Amharic and evaluate its psychometric properties.  We followed an intercultural adaptation procedure to translate and adapt the POP-SS.  One hundred and eighty-six women with POP symptoms completed the Amharic POP-SS and Prolapse Quality of Life (P-QoL) questionnaires.  All women were examined using a simplified Pelvic Organ Prolapse Quantification (SPOP-Q) system and were divided into four groups based on the POP-Q scores as stage 1, 2, 3, and 4.  Internal consistency and test-retest reliability were determined using Cronbach's alpha and the intraclass correlation coefficient (ICC), respectively.  Criterion validity was assessed against the SPOP-Q stage and the P-QoL scale.  Furthermore, we tested construct validity using exploratory factor analysis.  The POP-SS score was successfully translated and achieved good content validity.  It had high internal consistency (Cronbach's alpha = 0.86) and test-retest reliability (ICC = 0.81; p < 0.001).  There was a statistically significant difference among four groups of stages in POP-SS score.  and women with stage 3 had the highest median score (Kruskal-Wallis test; p < 0.05).  The POP-SS score was also significantly correlated with the P-QoL score (Spearman's correlation coefficient = 0.28, p < 0.001).  The exploratory factor analysis identified two factors, namely, physical symptoms and evacuation symptoms.  The POP-SS scale was successfully translated to Amharic and appears reliable and valid for women with symptoms of POP.  However, further studies are needed to evaluate its responsiveness.