Population and formal genetics of the human C81(alpha-gamma) polymorphism. 
One hundred and ninety-six unrelated healthy individuals and 30 families with 75 offspring have been studied for the C81(alpha-gamma) polymorphism.  The following allele frequencies were calculated: C81*A = 0.5536; C81*B = 0.4286; C81*A1 = 0.0178.  Observed and expected phenotype frequencies were in a good agreement according to the Hardy Weinberg law.  No exceptions from the mode of inheritance were found.  In family W the segregation of the rare allele C81*A1 could be followed.  Comparing the results of this study with previous data from Boston and Oslo, a combined technology including C8-dependent lysis and C8 structural variation is suggested for future investigations.