XDS

XDS could refer to:

 Extended Data Services, a US standard for TV metadata transmission
 Direct Save Protocol (X Window Direct Save Protocol), an additional feature of the X Window System graphical user interface for Unix-like computer operating systems
 Cross Enterprise Document Sharing, a system for sharing clinical documents between healthcare institutions
 X-ray diffuse scattering, a materials analysis technique
 Xerox Data Systems, the name for Scientific Data Systems after it was purchased by Xerox Corporation
 Springfield Armory XDS, a variant of the Croatian-made HS2000 pistol designed for pocket carry
 External Development Summit, an event for the video game industry
 X-ray Detector Software, a software for processing single-crystal monochromatic diffraction data