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To overcome this disadvantage, the investigators aim to evaluate a single device that integrates in its tip bipolar radiofrequency and microwave, the Speedboat Ultraslim (Creo Medical, UK) for cutting and coagulation during POEM procedure. Some of the promise's advantages derived from its use are: (1) less inflammation... |
This single-center, prospective, interventional study will include patients with achalasia submitted to POEM procedure, with or without fundoplication (POEM-F). All stages (mucosal incision, submucosal tunneling, myotomy) of POEM will be performed using the Speedboat ultraslim flexible catheter. Technical and clinical ... |
<|newrecord|> nctId: NCT06264453 id: KH-001-D201 briefTitle: A Study to Evaluate the Efficacy and Safety of KH001 in Patients With Dentin Hypersensitivity overallStatus: NOT_YET_RECRUITING date: 2024-03-11 date: 2024-08-23 date: 2024-08-30 date: 2024-02-20 date: 2024-02-21 name: HysensBio Co., Ltd class: INDUSTRY brief... |
<|newrecord|> nctId: NCT06264440 id: 283HV104 briefTitle: A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-12 date: 2024-05-07 date: 2024-05-07 date: 2024-02-20 date: 2024-03... |
<|newrecord|> nctId: NCT06264427 id: KVUG - 2022 - 10 briefTitle: Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland overallStatus: RECRUITING date: 2022-07-15 date: 2025-12-31 date: 2026-12-31 date: 2024-02-20 date: 2024-02-20 name: Steno Diabetes Center Greenland class: OTHER name: ... |
The main questions it aims to answer are: |
* Are monogenetic diabetes variants associated with the same risk of developing late diabetic complications as other types of diabetes? |
* Can genotyping and thereby personalized medicine be implemented in Greenland, and can personalized medicine lead to improved treatment? |
* What is the prevalence of sleep apnea among high-risk individuals in Greenland? |
* Is it possible to develop and implement a simple algorithm for the identification of sleep apnea in Greenland that can ensure treatment of severe sleep apnea? |
Participants will: |
* Answer WHO-5 and FOSQ-10 questionnaires regarding quality of life and functional outcomes of sleepiness |
* Perform VAGUS examinations for Cardiovasculare Autonomic Neuropathy |
* Clinical examination of height, weight, circumference of hip, waist and neck, Friedman tonsil and tongue score, nasal air flow, nasal septal deviation |
* Blood samples for full genome sequencing conditions: Diabetes Mellitus, Type 2 conditions: Obesity, Morbid conditions: Obstructive Sleep Apnea conditions: MODY conditions: Diabetic Retinopathy conditions: Diabetic Neuropathies studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interve... |
'For the intervention, participants will be screened for obstructive sleep apnea (OSA). Participants with signs of OSA will be offered treatment with Continuos Positive Airway Pressure. primaryPurpose: TREATMENT masking: NONE count: 1000 type: ESTIMATED name: Whole genome sequencing name: VAGUS name: NightOwl name: CPA... |
<|newrecord|> nctId: NCT06264414 id: DTT106-III-0123 briefTitle: Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia acronym: AUSTRÁLIA overallStatus: NOT_YET_RECRUITING date: 2025-02 date: 2026-06 date: 2027-07 date: 2024-02-20 date: 2024-02-20 name: ... |
<|newrecord|> nctId: NCT06264401 id: menopausal with osteoporsis briefTitle: Treatment Exercises With Core Stability and Dynamic Resistance Exercise for Postmenopausal Women With Osteoporosis overallStatus: NOT_YET_RECRUITING date: 2024-02-22 date: 2024-12-31 date: 2024-12-31 date: 2024-02-20 date: 2024-02-21 name: Cai... |
treatment exercises the experimental group performed core stability and dynamic resistance exercises, a 45-min lumbar-pelvic/core strength and stability exercise program which include 5 min warming up and 5 min cooling down at the end of the session each exercise was executed for three sets of 15 seconds, which gradual... |
<|newrecord|> nctId: NCT06264388 id: 20231234 id: R21CA282543 type: NIH link: https://reporter.nih.gov/quickSearch/R21CA282543 briefTitle: DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma overallStatus: RECRUITING date: 2024... |
<|newrecord|> nctId: NCT06264375 id: E-SPORT briefTitle: Effect of a Specific and General Physical Exercise Intervention on Gaming and E-Sport Performance acronym: E-SPORT overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-19 date: 2024-04-19 date: 2024-09-30 date: 2024-02-20 date: 2024-04-23 name: Universitaet Innsbru... |
Participants are gamers and e-athletes who play at least \>2hours peer week. The main questions it aims to answer are: |
* Does physical training have an effect on e-sport related abilities (hand grip strength, reaction, anticipation) |
* Does the training of specific elements, which aim at these abilities "out-game", transfer on the actual skills needed using a keyboard and mouse |
Participants will be randomly - but mediated by hours of playing per week - distributed in 1 of 3 groups. |
* Group 1 will 3 times per week for 30 minutes perform a specific physical training with focus on abilities needed in e-sport (grip strength, reaction, anticipation) over a timespan of 8 weeks. |
* Group 2 will perform a similar physical training (load, intensity) to Group 1, but without specific elements. |
* Group 3 will serve as control group without any training. |
Researchers will compare Group 1, Group 2 and Groups 3 to see if the different trainings (Group 1 and Group 2) have different effect on e-sport performance and if no training (Group 3) differs in e-sport performance development. conditions: Physical Activity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED i... |
<|newrecord|> nctId: NCT06264362 id: K23AG081547 type: NIH link: https://reporter.nih.gov/quickSearch/K23AG081547 id: 1K23AG081547-01 type: NIH link: https://reporter.nih.gov/quickSearch/1K23AG081547-01 briefTitle: Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia overa... |
In Part 1 - The investigators are inviting the following people to participate in an interview: |
1. Individuals aged 60 years or older who do not live in a nursing home and have both memory issues and knee pain. |
2. Care partners of people with knee pain and memory issues. A care partner can be a family member or friend who helps regularly. |
3. Clinicians (exercise physiologists or rehabilitation therapists like physical and occupational therapists) who have worked with older adults with memory issues and knee pain. |
The goal of these interviews is to learn from the experiences of people with memory issues and knee pain and those who care for them. From these interviews, the investigators hope to design a non-drug, tailored physical activity program that will be interesting and helpful in managing knee pain for older adults with me... |
For people with memory problems and knee pain and their care partners: The investigators will ask some questions to determine eligibility to participate in the study. |
Those who qualify for the study will be invited to participate in an interview that could be completed online or in person (Philadelphia, PA). The interview could last up to 90 minutes (1 and a half hours) and can be completed as one or multiple sessions. |
For clinicians: Participants will engage in a 90-minute focus group with other clinicians where lunch will be served if in person. Those participating in an online focus group will receive a gift card equal to the value of lunch. |
In Part 2 - The program developed in Part 1 will be tested. The program will be physical activity-based. Specific program details for part 2 will be provided as they emerge. Participants can choose to sign up for either or both parts. Signing up for Part 1 does not mean participants have to sign up for Part 2. |
Please contact us for any questions. conditions: Pain, Chronic conditions: Dementia, Mild conditions: Mobility Limitation conditions: Physical Disability conditions: Osteo Arthritis Knee conditions: Mild Cognitive Impairment studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventio... |
<|newrecord|> nctId: NCT06264349 id: 05102023 briefTitle: Women and Maternity: Development of a Nutritional Education Project acronym: MATER overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-05-15 date: 2025-11-30 date: 2024-02-16 date: 2024-02-16 name: University of Pavia class: OTHER briefSummary: The "fi... |
Therefore, an educational program on an appropriate lifestyle during the "first 1000 days" can represent a crucial primary prevention strategy in reducing the risk of developing obesity and non-communicable diseases (NCDs) during childhood and later adulthood. conditions: Pregnancy conditions: Lactation studyType: INTE... |
<|newrecord|> nctId: NCT06264336 id: UIC AHS Pilot 2024 briefTitle: Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-16 date: 2024-02-28 name: University of Illinois ... |
<|newrecord|> nctId: NCT06264323 id: UI-5487 briefTitle: Incidence of Acute Injuries in Boxing overallStatus: COMPLETED date: 2017-09-01 date: 2018-05-30 date: 2018-11-30 date: 2024-02-16 date: 2024-02-16 name: University of Iceland class: OTHER briefSummary: A prospective cohort study with 9 months follow up was carri... |
<|newrecord|> nctId: NCT06264310 id: R2R01-WHF-201 briefTitle: To Evaluate the Safety, Tolerability and Efficacy of R2R01 Combined With SOC as Compared to SOC Alone in Outpatients With Worsening Heart Failure (WHF) overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-01 date: 2025-03 date: 2024-02-16 date: 2024-0... |
<|newrecord|> nctId: NCT06264297 id: 01-22-270-111 briefTitle: High-Voltage Pulsed Radiofrequency of the Lumbar Dorsal Root Ganglion for the Treatment of Chronic Lumbar Radicular and Neuropathic Pain; A Prospective, Doble-blinded and Randomized Controlled Trial acronym: Radiofrequency overallStatus: RECRUITING date: 20... |
<|newrecord|> nctId: NCT06264284 id: 2023PI163 briefTitle: Emergency (Red Code) Cesarean Section : Maternal and Fetal Prognosis Depending on Anesthetic Modalities in a Level 3 Maternity Ward overallStatus: COMPLETED date: 2018-07-19 date: 2023-07-19 date: 2023-07-19 date: 2024-02-16 date: 2024-02-16 name: Central Hospi... |
This study occurred in a Level 3 Maternity Ward. conditions: Anesthesia Complication studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 150 type: ACTUAL name: epidural anesthesia name: general anesthesia measure: To evaluate whether the type of anesthesia used influences the oc... |
<|newrecord|> nctId: NCT06264271 id: GIP-22-NL-06-203 briefTitle: The Effect of Nutrition Education on Glycemic Control in Patients With Type 1 Diabetes overallStatus: COMPLETED date: 2022-02-01 date: 2023-12-31 date: 2024-02-01 date: 2024-02-16 date: 2024-02-20 name: Charles University, Czech Republic class: OTHER nam... |
<|newrecord|> nctId: NCT06264258 id: STUDY2023_00000285 briefTitle: Game-based Pediatric Diabetes Education acronym: DVx-T1D overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2025-06-30 date: 2024-02-16 date: 2024-02-20 name: Carnegie Mellon University class: OTHER name: University of Pittsburgh briefSu... |
The investigators hypothesize that adoption of DVx-T1D™ by T1D patients will positively influence healthy dietary and physical activity behaviors by providing nutrition and lifestyle education through a playful, Artificial Intelligence (AI)-based, cartoon-style medium of mobile gaming, and result in improvements in the... |
The study will also assess changes in children's knowledge about the measured outcomes and investigate the feasibility and acceptability of game adoption and the barriers and challenges faced by patients, families and clinicians. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 80 type: ESTIMATED name: DVx-T1D™ app... |
<|newrecord|> nctId: NCT06264245 id: 2022-126 id: 2023-A00985-40 type: OTHER domain: ID RCB briefTitle: Users of Remote Conferencing and Compression of Sound Dynamics : Auditory Effects acronym: COMPRESSED overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-01-15 date: 2025-01-15 date: 2024-02-16 date: 2024-03-0... |
* be subject to high exposure to compressed sound, as defined by professional participation in events on broadcast platforms using sound signal processing systems, over the last 3 years, |
* be subject to moderate or limited exposure to compressed and manipulated sound, equivalent to that of a student following certain distance learning courses. on a videoconferencing platform, alternating with other face-to-face courses, with the ability to listen during breaks, which have been taught for a maximum of 2... |
The main objective of the COMPRESSED study is to evaluate the auditory effects of exposure to manipulated sounds (compression, filtering, equalisation, accentuation, etc.) from sound distribution platforms on the auditory system of participants who are regularly exposed to these sounds as a result of their professional... |
<|newrecord|> nctId: NCT06264232 id: AT ELANA 841P-BER-302-19 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-02-16 date: 2024-02-20 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06264219 id: H-24002284 briefTitle: Restoration of the Gut Microbiome After Cesarean Section acronym: RestoreGut overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-11-30 date: 2026-11-30 date: 2024-02-16 date: 2024-02-16 name: Professor Klaus Bønnelykke class: OTHER briefSummary: This... |
<|newrecord|> nctId: NCT06264206 id: CALLA_IVF_KIR briefTitle: Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype overallStatus: COMPLETED date: 2022-01-01 date: 2022-12-31 date: 2023-12-31 date: 2024-02-16 date: 2024-02-16 name: Calla IVF Center class: OTHER ... |
<|newrecord|> nctId: NCT06264193 id: Rowers briefTitle: The Impact of Hypoxia on the Biochemical and Morphological Parameters of Blood in Rowers. acronym: IHOBMPBR overallStatus: COMPLETED date: 2014-11-30 date: 2014-12-21 date: 2014-12-21 date: 2024-02-16 date: 2024-02-16 name: Poznan University of Physical Education ... |
<|newrecord|> nctId: NCT06264180 id: RP1-104 briefTitle: VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3) overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2029-01-01 date: 2034-08-31 date: 2024-02-16 date: 2024-02-16 name: Replimune Inc. cla... |
<|newrecord|> nctId: NCT06264167 id: NODE briefTitle: NODE (groiN ultrasOunD cancEr) acronym: NODE overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-03-31 date: 2028-03-31 date: 2024-02-16 date: 2024-02-16 name: Queensland Centre for Gynaecological Cancer class: OTHER_GOV name: Royal Brisbane and Women's Ho... |
30 eligible females aged 18 or older with clinically stage 1b or 2 vulvar cancer will receive a bilateral groin node ultrasound up to 30 days prior to planned surgery: |
Participants with normal/negative baseline groin ultrasounds will be randomly assigned to two groups (2:1 randomisation): one group undergoing radical procedures (groin lymph nodes are not removed) with bilateral groin ultrasound surveillance in conjunction with clinical examinations every 2 months, and the other group... |
Participants with suspicious/indeterminate baseline groin ultrasound (third group) will receive an upfront full groin LND or SNB, consistent with the current standard treatment, according to local clinical practice management guidelines. primaryPurpose: OTHER masking: NONE count: 30 type: ESTIMATED name: High-resolutio... |
<|newrecord|> nctId: NCT06264154 id: 854051 id: R01CA287474-01 type: NIH link: https://reporter.nih.gov/quickSearch/R01CA287474-01 briefTitle: The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-06 date... |
<|newrecord|> nctId: NCT06264141 id: NONS-RARS-01 briefTitle: Evaluation of Nitric Oxide Nasal Spray (NONS) for Treatment of Recurrent Acute Rhinosinusitis acronym: NONS-RARS-01 overallStatus: RECRUITING date: 2024-01-16 date: 2024-06 date: 2024-09 date: 2024-02-16 date: 2024-02-16 name: Sanotize Research and Developme... |
<|newrecord|> nctId: NCT06264128 id: TheraPAP Comfort briefTitle: TPAP for Comfort in OSA overallStatus: RECRUITING date: 2024-03-08 date: 2024-05-31 date: 2024-06-30 date: 2024-02-16 date: 2024-03-18 name: SleepRes Inc. class: INDUSTRY briefSummary: TheraPAP is a prototype device (with full documented electrical and i... |
<|newrecord|> nctId: NCT06264115 id: Soh-Med-24-01-05MS briefTitle: Outcomes of Three Ports Versus Four Ports Laparoscopic Cholecystectomy, Sohag General Surgery Department Experience overallStatus: ENROLLING_BY_INVITATION date: 2024-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-16 date: 2024-02-20 name: Sohag ... |
<|newrecord|> nctId: NCT06264102 id: 2024/1/1 briefTitle: Influence of Dalcroze Eurhythmics on Pains in Older Women overallStatus: COMPLETED date: 2019-01-11 date: 2019-03-08 date: 2019-07-15 date: 2024-02-16 date: 2024-02-16 name: Poznan University of Physical Education class: OTHER briefSummary: In this study, we att... |
<|newrecord|> nctId: NCT06264089 id: 202015 briefTitle: Effects of Preservation Rhinoplasty Nasal Valve Angle and Area overallStatus: COMPLETED date: 2020-08-06 date: 2023-08-30 date: 2023-08-30 date: 2024-02-16 date: 2024-02-16 name: Yuzuncu Yıl University class: OTHER briefSummary: The study planned to compare the in... |
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