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The primary goal of this prospective observational study is to understand why some patients with M. avium lung disease have persistent or recurrent M. avium in their sputum despite treatment. The aim is to understand whether it is usually due to treatment failure or new infection. conditions: Mycobacterium Avium condit... |
<|newrecord|> nctId: NCT06266429 id: STUDY00001304 briefTitle: Metabolomic Profiling of Racial Disparity overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-12-31 date: 2026-12-31 date: 2024-02-20 date: 2024-02-20 name: Olubukola Nafiu class: OTHER briefSummary: Tonsillectomy ± adenoidectomy (T\&A) is one of the... |
<|newrecord|> nctId: NCT06266416 id: 115207 briefTitle: IMARA for Black Male Caregivers and Girls Empowerment (IMAGE) acronym: IMAGE overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2027-05-31 date: 2028-05-31 date: 2024-02-20 date: 2024-04-24 name: University of Illinois at Chicago class: OTHER name: Universit... |
The researchers will simultaneously evaluate implementation determinants (barriers, facilitators, constraints) and processes at Community Based Organizations working through the 3 steps of the implementation model (Prepare, Roll out, and Sustain). primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: INVE... |
<|newrecord|> nctId: NCT06266403 id: STUDY00024154 briefTitle: Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2029-03 date: 2029-03 date: 2024-02-20 date: 2024-02-20 name: Penn State University class: OTHER briefSum... |
The question is, What are the effects of communicative interaction on verbal communication in people with ALS? |
Participants will read words and sentences while they are in a solo setting and interactive setting. conditions: Amyotrophic Lateral Sclerosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: PALS and age-matched adults will participate in one solo speech... |
Plans for Assignment - This is a single group study in which all participants will engage in the same tasks. primaryPurpose: BASIC_SCIENCE masking: NONE count: 300 type: ESTIMATED name: Structured Communicative Interaction name: Clear Speech name: Unstructured communicative interaction name: Clear Speech Structured Com... |
<|newrecord|> nctId: NCT06266390 id: 855007 briefTitle: Engaging sgACC With TMS for Depression overallStatus: NOT_YET_RECRUITING date: 2024-06-30 date: 2026-01-30 date: 2026-04 date: 2024-02-20 date: 2024-04-18 name: University of Pennsylvania class: OTHER name: National Institutes of Health (NIH) briefSummary: The pur... |
Study participation will include completing various questionnaires, clinical assessments, receiving a full transcranial magnetic stimulation (TMS) treatment intervention (every weekday for 4-6 weeks), and undergoing MRI scans, both with and without concurrent TMS. conditions: Depression conditions: Major Depressive Dis... |
<|newrecord|> nctId: NCT06266377 id: 11122023 briefTitle: AUT-MENU: Improving Meal Experience of Subjects With Autism Spectrum Disorder overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2025-06-01 date: 2025-11-30 date: 2024-02-20 date: 2024-02-20 name: University of Pavia class: OTHER name: Consiglio per la ric... |
<|newrecord|> nctId: NCT06266364 id: IRB-24-22 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-02-20 date: 2024-03-05 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06266351 id: LASIKIOP briefTitle: EVALUATION OF CATS TONOMETER PRISM IN LASIK SUBJECTS overallStatus: NOT_YET_RECRUITING date: 2024-02-12 date: 2024-06-01 date: 2024-08-01 date: 2024-02-20 date: 2024-02-20 name: Intuor Technologies, Inc. class: INDUSTRY briefSummary: The CATS Tonometer prism cli... |
<|newrecord|> nctId: NCT06266338 id: STU-2023-1118 briefTitle: Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix) overallStatus: RECRUITING date: 2024-03-11 date: 2025-10-31 date: 2026-10-31 date: 2024-02-20 date: 2024-03-13 name: University of Texas Southwestern Medical Cen... |
<|newrecord|> nctId: NCT06266325 id: 6138 briefTitle: Development and Validation of a Dementia Life Expectancy Tool overallStatus: COMPLETED date: 2010-04-01 date: 2022-12-31 date: 2022-12-31 date: 2024-02-20 date: 2024-03-04 name: University of Toronto class: OTHER name: Sunnybrook Research Institute name: Ottawa Hosp... |
<|newrecord|> nctId: NCT06266312 id: Maastricht UMC+ briefTitle: Feasibility of a Preoperative, Multimodal Lifestyle Intervention in Patients With Breastcancer acronym: APRIORI overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-03-01 date: 2024-02-20 date: 2024-02-20 name: Maastricht Univers... |
<|newrecord|> nctId: NCT06266299 id: 2269-001 briefTitle: A Study of KK2269 in Adult Participants With Solid Tumors overallStatus: RECRUITING date: 2024-01-25 date: 2027-12 date: 2027-12 date: 2024-02-20 date: 2024-04-26 name: Kyowa Kirin, Inc. class: INDUSTRY briefSummary: This is a first-in-human study of KK2269. Par... |
In Part 2, only participants with gastric adenocarcinoma, GEJ adenocarcinoma, esophageal adenocarcinoma, or NSCLC who have experienced at least one systemic therapy will be enrolled. In Part 2, the primary objective is to assess the safety and tolerability of KK2269 in combination with docetaxel and to determine the re... |
In both Part 1 and Part 2, participants who refuse to undergo standard therapy are also eligible. conditions: Advanced Solid Tumor conditions: Metastatic Solid Tumor conditions: Gastric Adenocarcinoma conditions: Gastroesophageal Junction Adenocarcinoma conditions: Esophageal Adenocarcinoma conditions: Non Small Cell L... |
<|newrecord|> nctId: NCT06266286 id: 2022-A00233-40 briefTitle: EXOPULSE Mollii Suit & Cerebral Palsy acronym: EXOCEP overallStatus: RECRUITING date: 2023-09-13 date: 2025-06-30 date: 2025-10-30 date: 2024-02-20 date: 2024-02-20 name: Institut De La Colonne Vertebrale Et Des Neurosciences class: OTHER briefSummary: Spa... |
Two weeks after the end of this phase (phase 1), a second phase of this trial, an open label phase, will be proposed for all patients to understand the effects of EXOPULSE Mollii suit and will consist of six months of active stimulation (sessions performed on a daily basis with the same parameters used for the active s... |
Summary: |
* Phase 1: randomized sham controlled crossover study (active versus sham condition) |
* Phase 2: Open label study (active condition) primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 32 type: ESTIMATED name: EXOPULSE MOLLII SUIT (active) name: EXOPULSE MOLLII SUIT (sham) measure: Improvement in balance using the PBS (Pédiatric B... |
<|newrecord|> nctId: NCT06266273 id: SBA 23/442 briefTitle: Investigating the Development, Validity, and Reliability of the Avoidance of Sports Activities Photo Scale overallStatus: RECRUITING date: 2024-01-01 date: 2024-06-30 date: 2024-08-30 date: 2024-02-20 date: 2024-02-20 name: Hacettepe University class: OTHER br... |
<|newrecord|> nctId: NCT06266260 id: 5486 briefTitle: Evaluation of the Performance of Direct Portal Pressure Measurement by Endoscopic Ultrasound in a Large Cohort of Patients With Advanced Chronic Liver Disease of Different Etiologies and Newly Diagnosed Clinically Significant Portal Hypertension (EVADIPP) acronym: E... |
<|newrecord|> nctId: NCT06266247 id: 06-2023/16 id: KMU-BAP type: OTHER domain: KMU briefTitle: How Sirtuin Levels Change During Behçet Disease overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-15 date: 2024-06-30 date: 2024-10-30 date: 2024-02-20 date: 2024-02-20 name: Karamanoğlu Mehmetbey University class: OTHER br... |
<|newrecord|> nctId: NCT06266234 id: APHP230600 id: 10723253 Bis type: OTHER domain: CESREES briefTitle: Characterization by Automated System on Infantile Spasmes acronym: REASSESS overallStatus: RECRUITING date: 2024-02-01 date: 2026-01 date: 2026-01 date: 2024-02-20 date: 2024-03-13 name: Assistance Publique - Hôpita... |
Because of its nature and duration, infantile spasm is often difficult to identify and is often confused with benign motor manifestations in children, such as hiccups or muscular jerks. This difficulty often leads to delays in diagnosis. Indeed, patients are often seen at the stage when cognitive regression has set in. |
The gold standard for diagnosing infantile spasms is to capture them on video-EEG to confirm the ictal correlate of the seizure. Although multiple variations are known, the ictal correlation is often a diffuse slow wave of high amplitude with subsequent electrodecrement. Yet continuous video electroencephalogram is an e... |
As part of Mr. Diop's thesis, the study team have developed a system for analyzing videos acquired in 2 dimensions from a simple smartphone or webcam and highlighting the existence of spasms in a child. The principle is to use computer vision and computer learning model to identify the spasms from these videos. The fir... |
The aim is to achieve a sensitivity and specificity of over 95% so that we can offer this detection system to healthcare professionals and parents of children who do not have rapid access to diagnosis. The aim is to develop a system enabling broad screening at the population level so that identified children can be mor... |
To achieve this goal, we need access to a standardized reference database that currently exists in the various pediatric electrophysiology laboratories of the Assistance Publique - Hôpitaux de Paris and the Île-de-France region. we propose using the films stored in these laboratories to teach the computer to recognize ... |
<|newrecord|> nctId: NCT06266221 id: APHP200073 id: 2022-000712-59 type: EUDRACT_NUMBER briefTitle: Severe Erythema Multiforme - CORTICO acronym: SEMCORTICO overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-06-01 date: 2027-11-01 date: 2024-02-20 date: 2024-02-20 name: Assistance Publique - Hôpitaux de Pari... |
The objectives of treatment for severe EM in the acute phase are to reduce the duration of lesions, prevent complications and mucosal sequelae. However, despite the lack of evidence and consensus some medical teams often use a short regimen of SCS hoping to obtain a quicker improvement of the condition. However, the us... |
This research will be a Phase III randomized, multicentric, double-blind, controlled trial with two parallel groups. The efficacy of prednisone, oral at 1 mg/kg/day for 3 days, tapered to 0.75 mg/kg/day for 3 days, 0.50 mg/kg/day for 3 days, 0.25 mg/kg/day for 3 days is compared to that of placebo, oral for 12 days or ... |
A stratification according to the food intake classification (0,1,2 vs 3) will be performed. |
An interim analysis is planned after the inclusion of 50 patients. Results of the interim analysis will be presented to the DSMB. During the interim analysis, inclusions may continue. conditions: Erythema Multiforme studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpo... |
<|newrecord|> nctId: NCT06266208 id: UCV/2021-2022/201 briefTitle: Utility of High-resolution Ultrasound to Evaluate Dorsal Osteophyte overallStatus: RECRUITING date: 2024-03-20 date: 2024-04-15 date: 2024-07-15 date: 2024-02-20 date: 2024-04-23 name: Fundación Universidad Católica de Valencia San Vicente Mártir class:... |
Nail curvature and osteophyte height will be measured in patients with clamp nails. Nail-phalange distance will also be measured with radiography and ultrasonography. |
The investigators to find a positive correlation between nail curvature and osteophyte height. Furthermore, a strong agreement is expected between both imaging techniques to measure nail-phalange distance. |
Ultrasonography could constitute a safe and effective alternative to radiology for detecting dorsal osteophytes in claw nails, especially in mild cases, follow-ups or young patients. conditions: Exostosis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 150 type: ESTIMATED n... |
<|newrecord|> nctId: NCT06266195 id: 5452 briefTitle: Spectroscopic Profiling of Extracellular Vesicles By Resonant Gold Nanostructures in the Infrared acronym: PROVEIR_1 overallStatus: RECRUITING date: 2023-03-15 date: 2023-12-31 date: 2025-02-28 date: 2024-02-20 date: 2024-02-20 name: Fondazione Policlinico Universit... |
<|newrecord|> nctId: NCT06266182 id: 2020/39/B/HS6/01927 briefTitle: The Effect of an Online ACT Intervention on Meaning-Making Process in Cancer Patients Following Hematopoietic Cell Transplantation overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-12 date: 2026-04 date: 2024-02-20 date: 2024-02-22 name: Univ... |
<|newrecord|> nctId: NCT06266169 id: fpc-2023-ivf-01 briefTitle: Application of Spectral Methods to Assess Gametes, Embryos, and Human Reproductive Capabilities overallStatus: RECRUITING date: 2023-09-20 date: 2024-02-28 date: 2025-12-31 date: 2024-02-20 date: 2024-02-20 name: Family Planning Center of Women's Welfare ... |
Embryos: 424 samples of the culture medium used from individually cultured blastocysts that were fresh and frozen before transferring a single embryo from the institution's internal biobank. Each sample is attributed based on the presence or absence of progressing pregnancy after transfer at 12-14 weeks. |
Semen: 340 samples of sperm from the internal biobank of couples undergoing ICSI, each sample is attributed based on the success or failure of the embryological stage. |
Endometrium: 300 samples of luminescent and visible spectra of patients' endometrium undergoing embryo transfer, each sample is attributed based on the presence or absence of ongoing pregnancy after transfer. |
For the prospective (interventional) stage of the study: |
For each object of study, the size of the dataset for prospective testing can only be determined after passing the observational part of the study. primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 1064 type: ESTIMATED name: making artificial intelligence based decisions of gamete, embryo and endometr... |
<|newrecord|> nctId: NCT06266156 id: BMU-HTUNC-01 briefTitle: Evaluation of The Effect of Consecutive Dental Visits on Dental Anxiety of Paediatric Patients overallStatus: COMPLETED date: 2023-08-05 date: 2023-11-03 date: 2023-12-27 date: 2024-02-20 date: 2024-02-20 name: Burdur Mehmet Akif Ersoy University class: OTHE... |
The main question\[s\]it aims to answer are: |
* Did the anxiety level of pediatric patients decrease in consecutive treatment sessions? |
* Were there changes in the physiological parameters related to stress level of pediatric patients in consecutive treatment sessions? |
Participants will fill out the questionnaire about dental anxiety in each dental treatment sessions before and after dental treatment. |
Researchers will compare paeditric patients have two caries on mandibular molars to see if changes dental anxiety levels and physiological parameters such as heart rates and oxygen saturations during dental treatments in consecutive dental treatment sessions. conditions: Dental Anxiety studyType: OBSERVATIONAL observat... |
<|newrecord|> nctId: NCT06266143 id: Y101D03 briefTitle: A Trial of Y101D in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Advanced Pancreatic Cancer overallStatus: ACTIVE_NOT_RECRUITING date: 2023-02-08 date: 2024-07-30 date: 2024-12-31 date: 2024-02-20 date: 2024-02-20 name: Wuhan YZY Biopharma... |
<|newrecord|> nctId: NCT06266130 id: EM-11-050087 briefTitle: Digital Bonding vs. Direct Bonding Study overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2024-08 date: 2026-08 date: 2024-02-20 date: 2024-02-20 name: 3M class: INDUSTRY briefSummary: This is a prospective, 2-armed, randomized, multi-site clinical stud... |
<|newrecord|> nctId: NCT06266117 id: SBF-HMS-GES-03 briefTitle: Pain, Anxiety, and Comfort Levels in Coronary Angiography overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-03-30 date: 2024-07-30 date: 2024-02-20 date: 2024-02-20 name: Abant Izzet Baysal University class: OTHER briefSummary: The study was de... |
<|newrecord|> nctId: NCT06266104 id: Protocol V1.4_04012024 briefTitle: Image Enhanced Endoscopy IBD overallStatus: RECRUITING date: 2024-04-03 date: 2025-12-31 date: 2026-03-01 date: 2024-02-20 date: 2024-04-12 name: Royal Perth Hospital class: OTHER briefSummary: Dye- spray chromoendoscopy remains the recommended gol... |
<|newrecord|> nctId: NCT06266091 id: M70102 briefTitle: Treat Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer With M701 Bispecific Antibody overallStatus: ACTIVE_NOT_RECRUITING date: 2021-11-24 date: 2024-03-31 date: 2024-12-31 date: 2024-02-20 date: 2024-02-20 name: Wuhan YZY Biopharma Co., Ltd. class: ... |
<|newrecord|> nctId: NCT06266078 id: School of Nursing briefTitle: A Human Factors Simulation Study Protocol for the Assessment of Usability of Innovative Personal Protective Equipment overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-01 date: 2024-12-15 date: 2024-02-20 date: 2024-02-20 name: University... |
After reaching consensus among the experts, the protocol will be piloted. Two identical sessions will be conducted using the cross-over method with all participants, so that the same participant performs the tasks using the innovative PPE and the comparative PPE, allowing the participants compare characteristics of bot... |
For the purpose of the development and piloting of this simulation protocol, the innovative PPE were selected according to compliance with the specifications required by the World Health Organization. It will enrolled 36 healthcare workers in piloting test. primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 9 type... |
<|newrecord|> nctId: NCT06266065 id: 8.1-23/260-2;02/013AG briefTitle: Impact of Coronary Sinus Flow Reducer on Coronary Microcirculation and Myocardial Ischemia overallStatus: RECRUITING date: 2024-02-27 date: 2026-06 date: 2026-06 date: 2024-02-20 date: 2024-03-06 name: Clinical Hospital Centre Zagreb class: OTHER br... |
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