input_ids
sequence
attention_mask
sequence
answer
stringlengths
1
933
start_positions
int64
157
69k
end_positions
int64
184
69.1k
token_type_ids
sequence
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Personal Protective Equipment
6,407
6,436
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it promotes germinal center formation, immunoglobulin (Ig) isotype switching, somatic hypermutation to enhance antigen affinity, and lastly, the formation of long-lived plasma cells and memory B cells
5,079
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considered safe and exhibits an adjuvant-like effect on mucosal and systemic immunity
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the first study to describe the role of NEAT1 in HTNV infection
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4 weeks
1,292
1,299
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weekly proportion of laboratory tests that are positive for influenza
404
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help scientists develop better ways to predict, prevent or limit the spread of viruses from bats to humans.
6,903
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a recombinant filamentous phage displaying a single polypeptide sequence on its surface (or more rarely, bispecific display achieved via fusion of polypeptides to two different capsid proteins)
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human papilloma virus (HPV), a DNA virus highly associated with head and neck cancers and respiratory papillomatosis,
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low-dose chest CT has been widely used in the screening of early lung cancer. It is well known that many early lung cancers are ground-glass opacities (GGO), so we believe that low-dose screening is also applicable for COVID-19. In addition, considering the rapid development of COVID-19, many CT 14 examinations may be conducted in the same individual to monitor disease progress. Low-dose scanning can reduce the radiation damage to patients.
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VEG-F-induced endothelial permeability
10,115
10,153
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the surface area can result in rapid absorption of the medication into the blood
3,446
3,526
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anticoccidial
3,094
3,107
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across the Arabian Peninsula and in parts of Africa
679
730
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high-throughput screening
4,596
4,621
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that viruses evolved in bat reservoirs possessing enhanced IFN capabilities could achieve more rapid within-host transmission rates without causing pathology to their hosts. Such rapidly-reproducing viruses would likely generate extreme virulence upon spillover to hosts lacking similar immune capacities to bats.
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3.2% [1.3%-7.6%]
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a 60 year old man from Bisha in the KSA
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qualitative real-time polymerase chain reaction
6,347
6,394
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within airway epithelial cells
7,487
7,517
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world-wide occurrence, ease of transmission and considerable morbidity and mortality effecting people of all ages
1,878
1,991
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modified vaccinia virus Ankara (MVA) and New York attenuated vaccinia virus NYVAC strains
6,675
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The advantages of Listeria are that it can invade a variety of cells, including antigen presenting cells (APCs). After invading the host cell, Listeria resides inside the phagosome; however, it can escape the phagosome with the help of listeriolysin O (LLO; Hly) and reside in the cytoplasm of the cells, thereby efficiently presenting antigen to both CD8 and CD4 T cells
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prior to availability of new conjugate vaccines confirmed S. pneumoniae and H. influenzae type B as the most important bacterial causes of pneumonia, with Staphylococcus aureus and Klebsiella pneumoniae associated with some severe cases. Respiratory syncytial virus was the leading viral cause, identified in 15-40% of pneumonia cases, followed by influenza A and B, parainfluenza, human metapneumovirus and adenovirus
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the presence of environmental factors such as allergens, pollutants, smoke, cold or dry air and pathogenic microbes in the airway
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The antiviral mechanism of carrageenan is based on the interference with viral attachment; as a consequence, viral entry is inhibited
5,365
5,498
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its receptor usage, interspecies transmission and pathogenesis.
9,058
9,121
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as candidate vaccines for cytomegalovirus (CMV)
18,710
18,757
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the average number of infections caused by one infected individual in a fully susceptible population
46,950
47,050
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betacoronavirus
4,258
4,273
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lower environ- mental temperatures and human nasal temperatures (bene- ficial to thermolabile Viruses such as influenza), optimal humidity, increased crowding indoors, and imperfect ven- tilation due to closed windows and suboptimal airflow
11,707
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at least 10
3,858
3,869
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alveolar macrophages
18,323
18,343
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global childhood population from 605 million in 2000 to 664 million in 2015
2,274
2,349
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specific antibody responses to the HA, and to a lesser extent NA proteins for protection.
5,071
5,160
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Human metapneumovirus (HMPV)
1,691
1,719
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Pseudorabies (PRV) and Rabies viruses (RABV)
2,185
2,229
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over half
18,779
18,788
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the construction of a chimeric CoV with a bat CoV S gene (SHC014) in the backbone of a SARS CoV that has adapted to infect mice (MA15) and is capable of infecting human cells
2,585
2,759
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Ae. aegypti and Ae. albopictus
2,164
2,194
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Global alignment of case definitions
67,480
67,516
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how viral induced changes to the upper airway may contribute to chronic airway inflammatory disease exacerbations, to provide a unified elucidation of the potential exacerbation mechanisms initiated from predominantly upper airway infections.
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time-consuming and expensive
3,293
3,321
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tobacco mosaic virus
2,689
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the prevalence of different respiratory viral infections in causing exacerbations in chronic airway inflammatory diseases.
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The categorization of hantaviruses as belonging to the family Bunyaviridae is due in part to
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into five compartments: susceptible people (S P ), exposed people (E P ), symptomatic infected people (I P ), asymptomatic infected people (A P ), and removed people (R P ) including recovered and death people.
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the importance of the virome within the airway microbiome environment and its impact on subsequent bacterial infection.
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descendants of the 1918 Virus still persists enzootically in pigs. They probably also circulated continuously in humans, undergoing gradual antigenic drift and causing annual epidemics, until the 1950s. With the appearance of a new H2N2 pandemic strain in 1957 (“Asian flu”), the direct H1N1 Viral descen- dants 0f the 1918 pandemic strain disappeared from human circulation entirely, although the related lineage persisted enzootically in pigs.
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an outbreak in 1993–94 in the southwestern United States
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the antiviral state induced by the interferon pathway protects live cells from mortality in tissue culture, resulting in in vitro epidemics of extended duration that enhance the probability of establishing a long-term persistent infection.
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that bats and rodents are the gene sources of most αCoVs and βCoVs, while avian species are the gene sources of most δCoVs and γCoVs.
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Local elaboration of inflammatory and chemotactic mediators
17,252
17,311
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readily manipulated
19,888
19,907
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Lee et al. (2002) engineered M13 phage to display a ZnS-binding peptide on pIII and showed that, in the presence of ZnS nanoparticles, they selfassemble into highly ordered film biomaterials that can be aligned using magnetic fields.
35,140
35,373
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on the day of illness onse
5,283
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MERS-CoV has a broader tropism, grows more rapidly in vitro, more rapidly induces cytopathogenic change, triggers distinct transcriptional responses, makes use of a different receptor, induces a more proinflammatory state and has a delayed innate antiviral response compared to SARS-CoV.
68,137
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it has the highest sensitivity at the earliest time point in the acute phase of infection
20,181
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Despite being a major cause of exacerbation, reports linking respiratory viruses to acute exacerbations only start to emerge in the late 1950s (Pattemore et al., 1992) ; with bacterial infections previously considered as the likely culprit for acute exacerbation
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patchouli alcohol possesses anti-influenza A (H2N2) virus activity
18,530
18,596
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a highly dynamic and structured membrane-less sub-nuclear compartment
565
634
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25.74%
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the nutrient profile in the airway through release of previously inaccessible nutrients that will alter bacterial growth
23,999
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using high throughput or "deep" sequencing methods for complete genome deduction
51,231
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in 2012
413
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LAIV immunization induces serum antibody responses, mucosal antibody responses (IgA), and T cell responses.
4,560
4,667
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particle swarm optimization
4,668
4,695
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less than 80 % identity between the amino acid sequence of MERS ORF 1ab and betacoronavirus relatives, Tylonycteris bat HKU4 and Pipistrellus bat HKU5
12,220
12,370
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a first or spring wave began in March 1918 and spread unevenly through the United States, Europe, and possibly Asia over the next 6 months
9,822
9,959
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Compound Topographical Index (CTI, also known as Topographical Wetness Index) is a measure of the tendency for water to pool. Studies in Thailand and elsewhere [54] have shown that the extent of surface water is a strong risk factor, possibly due to the role of water in long-range transmission and persistence of the virus. I
18,005
18,331
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infectious bronchitis virus (IBV)
710
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to elucidate the proximate causes of breeding failure behind the recent decline in productivity in the Spanish Pyrenees
662
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RoNi/7.1 (Rousettus aegyptiacus) cells
9,498
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544 base pairs
8,393
8,407
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enables modification of the vectors to attenuate the virus or enhance immunogenicity
7,085
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when not all exacerbation events occurred during the viral infection but may also occur well after viral clearance (Kim et al., 2008; Stolz et al., 2019) in particular the late onset of a bacterial infection
15,414
15,621
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a triterpene saponine
3,358
3,379
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~ 85% similarity
6,742
6,758
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VP1-VP4, VP6 and VP7
4,217
4,237
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the Pyrenees
3,127
3,139
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Nine swabs (5.3% of positive swabs) revealed co-infections with two viruses identified, among which six concerned co-infections with influenza viruses.
1,110
1,261
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2-3 weeks
4,427
4,436
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intrinsic augmentation of immunity induced by the vector.
43,357
43,414
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too early to detect substantial intervention impact in many countries at earlier stages of their epidemic
15,611
15,716
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the presence of new parenchymal infiltrates
3,577
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sensitive, validated reverse transcriptase real-time polymerase chain reaction (RT-rtPCR)-based diagnostics were quickly described
4,612
4,742
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up to 81% of severe pneumonia deaths occur outside a hospital
3,756
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homeostasis, differentiation, embryonic development, and organ physiology
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selective index of >10
812
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some bats have an antiviral immune response called the interferon pathway perpetually switched on
5,247
5,344
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intratracheal or intranasal delivery
5,840
5,876
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HAdV-55 may cause severe ARDS in immunocompetent young men with blood type B
12,906
12,982
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substantial exposure risk for ICU staff because of the following reasons
3,763
3,835
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from 3 to 7 days
10,323
10,339
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677,243 people have been identified as having had close contact with infected patients of whom13,701
4,931
5,031
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