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okay and whats your weight being doing
okay and whats your weight being doing
and so do you have any sort of ideas what might be going on yourself or any concerns at this point
and so do you have any sort of ideas what be going on yourself or any concerns at this point
yeah im a bit worried just because its been so well controlled for few years now im worried that my is my adalimumab stopped working or is something else causing my symptoms
im a bit worried just because its been so well controlled few years now im worried that my my adalimumab stopped working or something else causing my symptoms
or what do you think
or what do think
yeah so theres a few things that might be going on to know we only need few different tests so one of them youre right it could be that the adalimumab kind of lost its effectiveness which sometimes happens and we can test for that by doing a blood test to check for the level of the drug in your body and also um sometimes you could develop antibodies against the drug as well
so theres few things that might be going on we need few different tests so one of them youre right it could be that the adalimumab kind of lost effectiveness which sometimes happens and we can test for that by doing a blood test to check for level of drug in your body and also um sometimes you could develop against the drug as well
and which can make it ineffective so we can easily check that and the other thing is that because youve had surgery in the past that can sometimes affect how something called the bile salts get reabsorbed um and sometimes that can cause diarrhoea if youve got high levels of bile salts in your bowel motions but thats quite easy to check for us well
and which can make it ineffective so we can easily that and the other thing is that because youve had surgery in past that can sometimes affect how something called bile salts get reabsorbed um and sometimes that can cause diarrhoea if youve got high levels of bile salts in your bowel motions but quite easy to check for us well
and of course you need to also think about whether your disease is actually flaring up as well so the other thing well arrange to do is a faecal calprotectin in which youve probably done before
and of course you need to also think about your disease actually flaring so the other thing well arrange to do is faecal calprotectin in which youve done before
just a stool test to cheque for inflammation and the bowel so if thats high we might need to look at your medication and think about making some changes
just a stool test to cheque for inflammation and the bowel so if thats high we might to look at your medication about making some
do you have any questions about all of that quite a lot of information
do you have any about all of that quite a lot of information
yeah its okay if you do need to change my medication like what would be the next step
yeah its okay if you do need to change my medication like what be the next step
so theres a few different options so there is a medication called and infliximab which is similar to adalimumab or we might look at you know switching you to a completely different drug um as well also also called the biologic different works in a different way in the bodies it is called vedolizumab but yeah i think first of all well get some up to date tests on first might need to get a ct scan or also an mri scan of your small bowel just to have a look and see if theres any inflammation in the bowel that might be you know causing your symptoms
so theres a few different options so there is a medication called and infliximab which is similar to adalimumab or we might look at you know switching you a completely different drug um as well also called the biologic different works in a different way in the bodies it is called vedolizumab yeah i think first all well some up to date tests on might need to get a scan also an mri scan of your small bowel just to have a look and see theres any in the bowel that might be you know causing your
and i had surgery before my treatment wasnt working do you think thats a possibility in the future
i had surgery before my treatment wasnt working do you think thats a possibility in the future
so i mean its always possible we have to always keep it at the back of our mind and hopefully they you know we can try and work out whats going on and that do something medically but yeah ofcourse we have to always think about surgery is as a possibility
so i mean its always possible have always keep it at the back of our mind and hopefully they you we try and out whats going on and that medically but yeah ofcourse we have to always think about is a possibility
yeah but hopefully not
yeah but hopefully not
yeah thats fine thank you very much for seeing me
yeah thats fine thank you very much for seeing me
so hello my names dr kosher im one of the gastroenterology doctors and this is the ibd clinic inflammatory bowel disease clinic can you tell me why youve been referred here today
so hello my names kosher one of the gastroenterology doctors and this is the ibd clinic inflammatory bowel disease clinic can you tell me why youve been referred here today
yes so have been having this sort of that having diarrhoea for quite a while theres been a bit of blood in it as well have been a bit a bit concerned so went to see my gp and theyve sent me here
yes so have been having this sort of that having diarrhoea for quite a while theres been a bit blood in it as well have been a bit a bit so went to see my gp theyve sent here
okay and how longs that been going on for
okay and how longs that been going on for
well its three months three month
well its three months three month
and prior to that where you well
and prior to that where you well
yeah ive been ive been absolutely ground before that yeah
yeah ive been ive been absolutely ground that yeah
and how often would you say youre moving your bowels each day
and often would you say moving your bowels each day
probably probably about three or four times i think you know
probably probably about three or times think you know
three or four times okay has it ever been more than that
three or four times okay it ever been more than that
it was you know it has been a couple times where its been maybe four or five or six or so
it was you know it has been a couple times where been maybe four or or six or so
okay and is the blood mixed in or is it just on white thing would you say
okay and is blood mixed in or is it just on thing would you say
and if you had any abdominal pain
and if you had abdominal pain
yeah but its been yeah its been quite a kind of crampy crampy pain yeah
yeah but its been yeah its been quite kind of crampy crampy pain
okay um any other symptoms that youve had that you can think of
okay um other symptoms youve had that you can think of
um ive noticed that my appetite have not really been eating eating as well as i used to ive got kind of funny rash on my my shin as well
um ive noticed that my appetite have not really been eating eating well as i used to got kind of funny rash on my my shin as well
okay when did that start
okay did that start
so that started about a couple months ago as well
that started about a couple months as well
and do you have rashes anywhere else
and do you have anywhere else
no its just on my shins
no its just on my shins
okay any other medical conditions that you have
okay other medical conditions that you have
yeah i had ive got asthma but never really bothers me sometimes i have to take my blue inhaler
yeah i had ive got asthma but never really me sometimes i have to my inhaler
okay and any other medications that youre taking
okay and any other medications that taking
and have you got any family history of any significant medical conditions
and have you got any history of any significant medical conditions
yes my my grand my grand dad had ostrich colitis
yes my my grand my grand dad had ostrich colitis
and any other anyone else in the family with inflammatory bowel disease
and any other else in the family with inflammatory bowel disease
no i dont think so
no dont think
okay so so far youve had some investigations done so weve taken some samples of your stool to make sure that theres no infection there and you also had a colonoscopy a couple of weeks ago did anyone go through the results with you
okay so so far youve had investigations done so weve taken some samples of your stool to make sure that theres no infection there and you also had a colonoscopy a couple of weeks ago did anyone through the results with you
no not really no
no not really no
so that we took some biopsies when we did the colonoscopy and it looks like you do have something called ulcerative colitis okay so they were in keeping with with that condition i dont know how much you know about inflammatory bowel disease or ulcerative colitis
so that we took some biopsies when we did the colonoscopy and it looks like you do have something called ulcerative colitis so were in keeping with with that condition i much you know about inflammatory bowel disease or ulcerative colitis
i know wee bit because i have seen my grandma my grandfather had it i dont know i dont know a lot
i know wee bit because i have seen my grandma my grandfather had it i dont know i dont know a lot
okay so its what we call a chronic condition so its something that youre going to have life long unfortunately um but its a condition that we can control very well with medications in the vast majority of people so to start with well start you on a course of steroids i dont think youve had any from your gp yet but that should help to sort of calm down the inflammation in your bowel and then well get you started on some other maintenance therapies im going into details of that on at the next consultation do you have any questions about that just at the moment
so its what we call a chronic condition so its something that youre going to have life unfortunately um but its a condition that we can control very well with medications in the vast majority people so to start with well start you a course of i dont think youve had from your gp yet but should help to sort of calm down the inflammation in your and then get you on some other maintenance therapies im going into details of that on at the next consultation do you questions about that just at the
um so um yeah sorry its just lot to take in
um so um yeah sorry its just to take in
so how long will be on these steroids for is that for lifelong
so how long will be on these steroids for that for lifelong
so the steroids are normally just for eight to sixty eight weeks until the inflammation has has died down
so the steroids are normally just for eight sixty eight weeks until the inflammation has has died down
and hopefully your bowel have it should be going back to normal
and hopefully your have it should be going back to normal
and you should know its less blood as well if that doesnt happen with the steroids then we would want to know about that in case we need to do some further investigations but in terms of maintenance therapies that we talked about you will be on those for longer term and often people are on them lifelong or certainly for years depending on the course of their disease
you should know less blood if that happen with the steroids then we would want to know about that in case we need to do some further investigations but in terms of maintenance that we talked you will be on for longer term and often people are on them lifelong or certainly for years on the course of their disease
okay so and well also have to arrange some surveillance colonoscopy for you as well just to make sure that you dont develop other conditions that are associated with inflammatory bowel disease okay
okay so well also have to arrange some surveillance colonoscopy for you as well to make sure that you develop other conditions that are with bowel disease okay
so well arrange it to see you back in clinic in about six weeks time for a review thank you
so well arrange it to see you back clinic about six weeks time for a review thank
hello my name is dr kosher and im one of the gastroenterology registrars at the ibd clinic can i take your name please
hello my name is kosher and im one of the gastroenterology registrars at the ibd clinic i take your name please
yeah its john smith
yeah its john smith
okay nice to meet you john so tell me whats been going on
okay nice to meet you john so tell me whats been going
well so ive had crohns quite a while now i was diagnosed in early early twenties but i just its been its been okay for a while but its just ive been feeling very just very tired and more lethargic less rested like a few weeks or so i have not been able to go to work i had to call in sick ive got the my bowels have been a bit more bit watery and ive been going a bit more often
well so ive had crohns quite a now i was diagnosed in early early but i just its okay for a while but just ive been feeling very just very tired and more lethargic less rested a few weeks or so i have not been able to go to to call in sick ive got the bowels have been a bit more bit watery and ive been going a bit more often
okay how often would you say youve been moving your bowels in the last few months
how often would you say youve been moving your bowels in the last few months
probably about three or four times a day so yeah
probably about three or four times a so yeah
okay and you said youve not noticed any blood in your bowel motions
okay and you said not noticed any blood in your motions
no theres been no blood its just been really watery
no theres been no blood its just been really watery
okay and does that tend to be worse at night or during the day
okay and does that tend to be worse at night or during
i wouldnt say that much of a difference really its sometimes im up in the night but sometimes its not every night
wouldnt say of a difference really its sometimes im up the night but sometimes its not every night
and have you been having any abdominal pain or cramping
and have you been having any abdominal pain or cramping
yeah wee bit of a cramping and abdominal pain its not been too bad but of often have this having abdominal pain i wouldnt say its too much different they are normal for me
yeah wee bit a cramping and abdominal pain its not been too bad but of often have this having pain i wouldnt say its too much different they are normal for me
okay and if you noticed any skin rashes at all
okay and if you noticed skin rashes at all
and i know that youve been on fortnightly adalimumab
and i know that youve on fortnightly
and how hows that been going
and how hows that been going
yeah its been its been fine since yeah since i had surgery in two thousand and fifteen and yeah ive been ive been okay since then but yeah its just kind of recently ive just not been feeling that great
yeah its been its been fine yeah i had surgery in two thousand and fifteen and yeah been ive been okay then but yeah its just kind of recently ive not been feeling that great
okay and any problems at the injection sites sort of skin reactions or
okay and any problems at the injection sites sort of skin reactions or
okay and if you had any trouble with swallowing
okay and if you had any trouble with swallowing
okay what about vomiting or feeling nauseated
okay what about or feeling nauseated
i say i felt a wee bit a wee bit sick but ive not actually actually been sick
i say i felt a wee bit a wee bit sick but ive not actually been
okay and have you required any steroid courses from your gp recently
okay and have you required any courses from your gp
no not recently no
not recently no
okay okay and any other medical conditions that you have
okay and any other medical conditions that you
um yes ive got ive got arthritis and ive also got hay fever and asthma as well
yes ive got ive got arthritis and ive also got hay fever and asthma as well
and any other medications that youre on other than the adalimumab
any other youre on other than the
so i take i take some diclofenac thats for my my arthritis
so i take i take some diclofenac thats for my my arthritis
are you taking that regularly
are you taking that regularly
have you noticed any stomach upset with that
have you noticed any stomach upset with that
i mean well i suppose i have to have this abdominal pain in my tummy so i dont know could that be could be connected to that
i mean well i suppose i have to have pain in my tummy so i dont know could be could be connected to
yeah possibly so we do find people here on long term nonsteroidal medications like diclofenac that kind of upset your stomach especially if youre not taking omeprazole or a medication like that with it so we need to be might need to address that do you have any insight or ideas about what might be causing your symptoms preferably the diarrhoea and the weight loss
possibly so we do find people here on term nonsteroidal medications like that kind of upset your stomach especially if youre not taking omeprazole or a medication like that it so we need to be need to address that do you have any insight or ideas about what might be causing your symptoms preferably diarrhoea and the loss
and well i suppose i just assumed thats my crohns with that was being watery but i dont know about but do you think it could be anything else
and well i suppose i just assumed thats crohns with that was being watery but i dont know about but do you think it could be else
so yeah i think theres a few different things it could be i noticed that youve not had a colonoscopy for quite some time in fact not said to you shortly after you were diagnosed so we might need to look at repeating that i think in the first instance will get some blood tests off to check in inflammatory markers and we need to send some samples of your stool off to make sure theres no infection and also send off a special stool test called fecal calprotectin and thats to look for inflammation in your bowel that might be related to the crohns disease i think depending on what those are well maybe decide on whether you need another camera test up up the tail end to have a look at the lining of the bowel so i think thats thats what we are doing just at that the moment how does that sound to you
so yeah i think theres a few different things it could be noticed that youve not a colonoscopy for quite some time in fact not said to you shortly after were diagnosed so we need to look at repeating that i think the first instance will get some blood tests off to check in inflammatory markers and we need to some samples of your stool off make sure theres no infection and also send off a stool test called fecal calprotectin and thats to look for inflammation in that might be related to the crohns disease i depending on what are well maybe decide on whether you another test up the tail end to have a look the lining the bowel so i think thats thats what we are doing just at that the moment how does that sound to you
yeah i mean yes yeah thats thats all right yeah i just yeah i didnt really think could be getting all these tests and things quite a lot to take in
yeah i mean yeah thats thats all right yeah i just yeah i didnt really think could getting all these and things quite a lot to take in
yeah do you think i need to change my medication to something else
yeah do you think i need to change my medication to something
so one of the things we can do is to check the level of the medication in your blood called the adalimumab profile or checking the antibodies and the level of the drug but at the moment i wouldnt change you from your adalimumab just until weve got a bit more information about whats going on
so one of the things we can do is to check the level of the medication in your blood called the adalimumab profile or the antibodies and the level of the drug but at the moment i wouldnt change you from adalimumab just until weve got a bit information about whats going on
okay you think i might need more surgery
you think i might need more surgery
well again it depends a little bit on the investigations we might you know depending on what they show we might need to go on and get mri scan of your bowel just to have a look and make sure there arent any other points of narrowing in the bowel like you had last time if thats the case then we might need to look at surgery but thats a lot further down the line for a moment okay
well again it depends a little bit on the we might you know depending on what they show we might need to go on and scan of your bowel just have a look and sure there arent any other points of narrowing in the like you had time if thats the case then we might need to look at surgery but thats a lot further down line for a moment okay
hello my names amy i am one of the gastroenterology doctors can i take your name
hello my names amy i am one of gastroenterology doctors can i take your name
okay nice to meet you rachel so tell me why youve been referred to the gastroenterology clinic today
okay nice to you rachel so tell why youve referred to the gastroenterology clinic today
so for the past three months ive had a lot of diarrhoea and sometimes its quite bloody as well and its scaring me now
so for past three months ive had a lot of diarrhoea and sometimes quite well and scaring now
oh and have you ever had anything like that in the past
oh and have you ever had anything like that in the past
over the past few years id say its been a bit iffy and intermittently having diarrhoea but its been worse over the past three months
over the past few years id say its been a bit iffy and intermittently diarrhoea but its worse over the past three
okay and that you are passing blood each time
okay and that you are passing blood each time
most times and its mixed with the stool and sometimes i see clots and things as well
most times and its mixed with the stool and sometimes i see clots and things as well
okay have you noticed any mucus in your bowel motions
okay have you noticed any in your bowel motions
yeah theres a lot of mucus
theres a lot of mucus
and does that been the case for quite a few months as well
does that been case quite a few months as well