Datasets:

dzjxzyd

/

ppic_small_canonical

like 0

O = C ( [O-] ) / C = C \ C ( = O ) [O-] . O = S ( = O ) ( [O-] ) [O-]

O = C ( [O-] ) / C = C \ C ( = O ) [O-] . O = S ( = O ) ( [O-] ) [O-]

MTALNWKPFIYGGLASITAECGTFPIDLTKTRLQVQGQPNDAKYKEIRYRGMMHAIVRIWREEGVKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFVDCPEDETLVLNAFCGVLSGVVSSCIANPTDVLKIRMQAQGNVMQGGMIVNFINIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRSIRDASNSSYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKKLNL

O = S ( = O ) ( [O-] ) [O-] . O = C ( [O-] ) / C = C \ C ( = O ) [O-]

O = S ( = O ) ( [O-] ) [O-] . O = C ( [O-] ) / C = C \ C ( = O ) [O-]

MTALNWKPFIYGGLASITAECGTFPIDLTKTRLQVQGQPNDAKYKEIRYRGMMHAIVRIWREEGVKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFVDCPEDETLVLNAFCGVLSGVVSSCIANPTDVLKIRMQAQGNVMQGGMIVNFINIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRSIRDASNSSYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKKLNL

O = S ( = O ) ( [O-] ) [O-] . O = C ( [O-] ) / C = C \ C ( = O ) [O-]

O = C ( [O-] ) / C = C \ C ( = O ) [O-] . O = S ( = O ) ( [O-] ) [O-]

MTALNWKPFIYGGLASITAECGTFPIDLTKTRLQVQGQPNDAKYKEIRYRGMMHAIVRIWREEGVKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFVDCPEDETLVLNAFCGVLSGVVSSCIANPTDVLKIRMQAQGNVMQGGMIVNFINIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRSIRDASNSSYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKKLNL

O = C ( [O-] ) / C = C \ C ( = O ) [O-] . O = S ( = O ) ( [O-] ) [O-]

O = C ( [O-] ) / C = C \ C ( = O ) [O-] . O = S ( = O ) ( [O-] ) [O-]

MTALNWKPFIYGGLASITAECGTFPIDLTKTRLQVQGQPNDAKYKEIRYRGMMHAIVRIWREEGVKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFVDCPEDETLVLNAFCGVLSGVVSSCIANPTDVLKIRMQAQGNVMQGGMIVNFINIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRSIRDASNSSYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKKLNL

C [C@H] ( O ) C S C C S ( = O ) ( = O ) [O-]

C [C@H] 1 C O 1 . O = S ( = O ) ( [O-] ) C C S

MLIRGEDVTIPTSMVGNYPNPRWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDIISDGRVHGDNYAEQALYYYYRRLGYDLKGGYLGFPIYSRLHAGTLTGEVRRHGAIMVEQAKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFIQIDEFTWPYFFEDWAIEAFNAAVDGVKNAKIIAHVCWGNWGGTPAYYPDETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNHPLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQDKLHALVEGTKIVRAELAKAKQAA

O = S ( = O ) ( [O-] ) C C S . C [C@H] 1 C O 1

C [C@H] ( O ) C S C C S ( = O ) ( = O ) [O-]

MLIRGEDVTIPTSMVGNYPNPRWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDIISDGRVHGDNYAEQALYYYYRRLGYDLKGGYLGFPIYSRLHAGTLTGEVRRHGAIMVEQAKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFIQIDEFTWPYFFEDWAIEAFNAAVDGVKNAKIIAHVCWGNWGGTPAYYPDETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNHPLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQDKLHALVEGTKIVRAELAKAKQAA

C [C@H] ( O ) C S C C S ( = O ) ( = O ) [O-]

O = S ( = O ) ( [O-] ) C C S . C [C@H] 1 C O 1

MLIRGEDVTIPTSMVGNYPNPRWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDIISDGRVHGDNYAEQALYYYYRRLGYDLKGGYLGFPIYSRLHAGTLTGEVRRHGAIMVEQAKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFIQIDEFTWPYFFEDWAIEAFNAAVDGVKNAKIIAHVCWGNWGGTPAYYPDETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNHPLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQDKLHALVEGTKIVRAELAKAKQAA

C [C@H] 1 C O 1 . O = S ( = O ) ( [O-] ) C C S

C [C@H] ( O ) C S C C S ( = O ) ( = O ) [O-]

MLIRGEDVTIPTSMVGNYPNPRWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDIISDGRVHGDNYAEQALYYYYRRLGYDLKGGYLGFPIYSRLHAGTLTGEVRRHGAIMVEQAKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFIQIDEFTWPYFFEDWAIEAFNAAVDGVKNAKIIAHVCWGNWGGTPAYYPDETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNHPLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQDKLHALVEGTKIVRAELAKAKQAA

C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 = C 2 C C C ( = O ) [C@@] 2 ( C ) C C C 1 = O . O

C [C@@H] 1 C C C ( = O ) C ( C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) = C 1 C C C ( = O ) [O-] . [H+]

MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS

[H+] . C [C@@H] 1 C C C ( = O ) C ( C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) = C 1 C C C ( = O ) [O-]

C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 = C 2 C C C ( = O ) [C@@] 2 ( C ) C C C 1 = O . O

MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS

O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 = C 2 C C C ( = O ) [C@@] 2 ( C ) C C C 1 = O

C [C@@H] 1 C C C ( = O ) C ( C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) = C 1 C C C ( = O ) [O-] . [H+]

MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS

[H+] . C [C@@H] 1 C C C ( = O ) C ( C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) = C 1 C C C ( = O ) [O-]

O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 = C 2 C C C ( = O ) [C@@] 2 ( C ) C C C 1 = O

MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS

O = O . O = C C = O . O

[H+] . O = C C ( = O ) [O-] . O O

MLSLLAVVSLAAATLAAPAASDAPGWRFDLKPNLSGIVALEAIVVNSSLVVIFDRATGDQPLKINGESTWGALWDLDTSTVRPLSVLTDSFCASGALLSNGTMVSMGGTPGGTGGDVAAPPGNQAIRIFEPCASPSGDGCTLFEDPATVHLLEERWYPSSVRIFDGSLMIIGGSHVLTPFYNVDPANSFEFFPSKEQTPRPSAFLERSLPANLFPRAFALPDGTVFIVANNQSIIYDIEKNTETILPDIPNGVRVTNPIDGSAILLPLSPPDFIPEVLVCGGSTADTSLPSTSLSSQHPATSQCSRIKLTPEGIKAGWQVEHMLEARMMPELVHVPNGQILITNGAGTGFAALSAVADPVGNSNADHPVLTPSLYTPDAPLGKRISNAGMPTTTIPRMYHSTVTLTQQGNFFIGGNNPNMNFTPPGTPGIKFPSELRIETLDPPFMFRSRPALLTMPEKLKFGQKVTVPITIPSDLKASKVQVALMDLGFSSHAFHSSARLVFMESSISADRKSLTFTAPPNGRVFPPGPAVVFLTIDDVTSPGERVMMGSGNPPPTLE

O O . [H+] . O = C C ( = O ) [O-]

O = O . O . O = C C = O

MLSLLAVVSLAAATLAAPAASDAPGWRFDLKPNLSGIVALEAIVVNSSLVVIFDRATGDQPLKINGESTWGALWDLDTSTVRPLSVLTDSFCASGALLSNGTMVSMGGTPGGTGGDVAAPPGNQAIRIFEPCASPSGDGCTLFEDPATVHLLEERWYPSSVRIFDGSLMIIGGSHVLTPFYNVDPANSFEFFPSKEQTPRPSAFLERSLPANLFPRAFALPDGTVFIVANNQSIIYDIEKNTETILPDIPNGVRVTNPIDGSAILLPLSPPDFIPEVLVCGGSTADTSLPSTSLSSQHPATSQCSRIKLTPEGIKAGWQVEHMLEARMMPELVHVPNGQILITNGAGTGFAALSAVADPVGNSNADHPVLTPSLYTPDAPLGKRISNAGMPTTTIPRMYHSTVTLTQQGNFFIGGNNPNMNFTPPGTPGIKFPSELRIETLDPPFMFRSRPALLTMPEKLKFGQKVTVPITIPSDLKASKVQVALMDLGFSSHAFHSSARLVFMESSISADRKSLTFTAPPNGRVFPPGPAVVFLTIDDVTSPGERVMMGSGNPPPTLE

O = O . O . O = C C = O

O O . O = C C ( = O ) [O-] . [H+]

MLSLLAVVSLAAATLAAPAASDAPGWRFDLKPNLSGIVALEAIVVNSSLVVIFDRATGDQPLKINGESTWGALWDLDTSTVRPLSVLTDSFCASGALLSNGTMVSMGGTPGGTGGDVAAPPGNQAIRIFEPCASPSGDGCTLFEDPATVHLLEERWYPSSVRIFDGSLMIIGGSHVLTPFYNVDPANSFEFFPSKEQTPRPSAFLERSLPANLFPRAFALPDGTVFIVANNQSIIYDIEKNTETILPDIPNGVRVTNPIDGSAILLPLSPPDFIPEVLVCGGSTADTSLPSTSLSSQHPATSQCSRIKLTPEGIKAGWQVEHMLEARMMPELVHVPNGQILITNGAGTGFAALSAVADPVGNSNADHPVLTPSLYTPDAPLGKRISNAGMPTTTIPRMYHSTVTLTQQGNFFIGGNNPNMNFTPPGTPGIKFPSELRIETLDPPFMFRSRPALLTMPEKLKFGQKVTVPITIPSDLKASKVQVALMDLGFSSHAFHSSARLVFMESSISADRKSLTFTAPPNGRVFPPGPAVVFLTIDDVTSPGERVMMGSGNPPPTLE

O O . [H+] . O = C C ( = O ) [O-]

O = C C = O . O . O = O

MLSLLAVVSLAAATLAAPAASDAPGWRFDLKPNLSGIVALEAIVVNSSLVVIFDRATGDQPLKINGESTWGALWDLDTSTVRPLSVLTDSFCASGALLSNGTMVSMGGTPGGTGGDVAAPPGNQAIRIFEPCASPSGDGCTLFEDPATVHLLEERWYPSSVRIFDGSLMIIGGSHVLTPFYNVDPANSFEFFPSKEQTPRPSAFLERSLPANLFPRAFALPDGTVFIVANNQSIIYDIEKNTETILPDIPNGVRVTNPIDGSAILLPLSPPDFIPEVLVCGGSTADTSLPSTSLSSQHPATSQCSRIKLTPEGIKAGWQVEHMLEARMMPELVHVPNGQILITNGAGTGFAALSAVADPVGNSNADHPVLTPSLYTPDAPLGKRISNAGMPTTTIPRMYHSTVTLTQQGNFFIGGNNPNMNFTPPGTPGIKFPSELRIETLDPPFMFRSRPALLTMPEKLKFGQKVTVPITIPSDLKASKVQVALMDLGFSSHAFHSSARLVFMESSISADRKSLTFTAPPNGRVFPPGPAVVFLTIDDVTSPGERVMMGSGNPPPTLE

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C [C@H] ( [NH3+] ) C ( = O ) [O-] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . [H+]

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C C [NH3+] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . O = C = O

MNEPIDPKSFPSQPLSPYIPMHHIGKGPYKTIFNVLSLNRDHIHWEDYLYKHTPCELVANPETNQQVWFKREDYFAPLSCYMNGKQGINGSKLRQAIWLMVEHLKAGGSPDLIHGTVVGSPQSPMATAVSRHFGGKTTTVLGATKPTTCMNHDMVKMSAWFGSEFNFVGSGYNSTIQPRCKKLIEQQNPKAYYLEYGITLDHTLHSPERIAGFHMLGGEQVANIPDHITDLIIPAGSCNSCTSILTGLAMHPKPNLKNVYLIGIGPNRLDFIESRLRIIGKQANLPHITDFTRCYHDNPDYVYGKKDLQHASKSVSLAGLLMGIREKGESEITLPRFAVHHWDLHTTNWVRYNDLMDYQWGDIELHPRYEGKVMTWIQQHKPELLNENTLFWIVGSKPYIEPMKAACPELSMPEQVPVNEFTPD

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C C [NH3+] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . O = C = O

[H+] . * O [C@H] 1 C [C@H] ( n 2 c c ( C O C [C@H] ( [NH3+] ) C ( = O ) [O-] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

MNEPIDPKSFPSQPLSPYIPMHHIGKGPYKTIFNVLSLNRDHIHWEDYLYKHTPCELVANPETNQQVWFKREDYFAPLSCYMNGKQGINGSKLRQAIWLMVEHLKAGGSPDLIHGTVVGSPQSPMATAVSRHFGGKTTTVLGATKPTTCMNHDMVKMSAWFGSEFNFVGSGYNSTIQPRCKKLIEQQNPKAYYLEYGITLDHTLHSPERIAGFHMLGGEQVANIPDHITDLIIPAGSCNSCTSILTGLAMHPKPNLKNVYLIGIGPNRLDFIESRLRIIGKQANLPHITDFTRCYHDNPDYVYGKKDLQHASKSVSLAGLLMGIREKGESEITLPRFAVHHWDLHTTNWVRYNDLMDYQWGDIELHPRYEGKVMTWIQQHKPELLNENTLFWIVGSKPYIEPMKAACPELSMPEQVPVNEFTPD

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C [C@H] ( [NH3+] ) C ( = O ) [O-] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . [H+]

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C C [NH3+] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . O = C = O

MNEPIDPKSFPSQPLSPYIPMHHIGKGPYKTIFNVLSLNRDHIHWEDYLYKHTPCELVANPETNQQVWFKREDYFAPLSCYMNGKQGINGSKLRQAIWLMVEHLKAGGSPDLIHGTVVGSPQSPMATAVSRHFGGKTTTVLGATKPTTCMNHDMVKMSAWFGSEFNFVGSGYNSTIQPRCKKLIEQQNPKAYYLEYGITLDHTLHSPERIAGFHMLGGEQVANIPDHITDLIIPAGSCNSCTSILTGLAMHPKPNLKNVYLIGIGPNRLDFIESRLRIIGKQANLPHITDFTRCYHDNPDYVYGKKDLQHASKSVSLAGLLMGIREKGESEITLPRFAVHHWDLHTTNWVRYNDLMDYQWGDIELHPRYEGKVMTWIQQHKPELLNENTLFWIVGSKPYIEPMKAACPELSMPEQVPVNEFTPD

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C C [NH3+] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . O = C = O

* O [C@H] 1 C [C@H] ( n 2 c c ( C O C [C@H] ( [NH3+] ) C ( = O ) [O-] ) c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-] . [H+]

MNEPIDPKSFPSQPLSPYIPMHHIGKGPYKTIFNVLSLNRDHIHWEDYLYKHTPCELVANPETNQQVWFKREDYFAPLSCYMNGKQGINGSKLRQAIWLMVEHLKAGGSPDLIHGTVVGSPQSPMATAVSRHFGGKTTTVLGATKPTTCMNHDMVKMSAWFGSEFNFVGSGYNSTIQPRCKKLIEQQNPKAYYLEYGITLDHTLHSPERIAGFHMLGGEQVANIPDHITDLIIPAGSCNSCTSILTGLAMHPKPNLKNVYLIGIGPNRLDFIESRLRIIGKQANLPHITDFTRCYHDNPDYVYGKKDLQHASKSVSLAGLLMGIREKGESEITLPRFAVHHWDLHTTNWVRYNDLMDYQWGDIELHPRYEGKVMTWIQQHKPELLNENTLFWIVGSKPYIEPMKAACPELSMPEQVPVNEFTPD

O . [NH3+] C C C ( = O ) N C C c 1 c c c ( O ) c ( O ) c 1

[NH3+] C C C ( = O ) [O-] . [NH3+] C C c 1 c c c ( O ) c ( O ) c 1

MSSGKILPRRQAVPVLYTRGTHYEVGFDMGRTFGSMIKNFLILSKPLNETYLPLYQSPKGRQIYNETLGSVKDSFPQYVRELEGVADGAEVEFHKLFLLHLDEILPQALKHQPRSKNQPTGCSTIIVNQKNCRLLGHTEDALTETLNHYYFVVAHIISDKPQGKYNVKEEHFMSLCYAGHLPGYTMSHNHHGLVFSINTISAELLRSGKTPRHFITRALLATSNVDDAFRVLKDAGVGAADACSINFTFLADPRQMCYNVEMAPSPDRKNESHLNIKEVPLGEHNYHVNQFDRIRQDQANDLMISSSISRMQTFGAYNPPMSEQDVRHMLGDVSGGVYCVWRENNSCDEVVKTIAVGIFDLSARTISLYSDNPSETEPHCRLPLLYK

[NH3+] C C C ( = O ) [O-] . [NH3+] C C c 1 c c c ( O ) c ( O ) c 1

O . [NH3+] C C C ( = O ) N C C c 1 c c c ( O ) c ( O ) c 1

MSSGKILPRRQAVPVLYTRGTHYEVGFDMGRTFGSMIKNFLILSKPLNETYLPLYQSPKGRQIYNETLGSVKDSFPQYVRELEGVADGAEVEFHKLFLLHLDEILPQALKHQPRSKNQPTGCSTIIVNQKNCRLLGHTEDALTETLNHYYFVVAHIISDKPQGKYNVKEEHFMSLCYAGHLPGYTMSHNHHGLVFSINTISAELLRSGKTPRHFITRALLATSNVDDAFRVLKDAGVGAADACSINFTFLADPRQMCYNVEMAPSPDRKNESHLNIKEVPLGEHNYHVNQFDRIRQDQANDLMISSSISRMQTFGAYNPPMSEQDVRHMLGDVSGGVYCVWRENNSCDEVVKTIAVGIFDLSARTISLYSDNPSETEPHCRLPLLYK

O . [NH3+] C C C ( = O ) N C C c 1 c c c ( O ) c ( O ) c 1

[NH3+] C C C ( = O ) [O-] . [NH3+] C C c 1 c c c ( O ) c ( O ) c 1

MSSGKILPRRQAVPVLYTRGTHYEVGFDMGRTFGSMIKNFLILSKPLNETYLPLYQSPKGRQIYNETLGSVKDSFPQYVRELEGVADGAEVEFHKLFLLHLDEILPQALKHQPRSKNQPTGCSTIIVNQKNCRLLGHTEDALTETLNHYYFVVAHIISDKPQGKYNVKEEHFMSLCYAGHLPGYTMSHNHHGLVFSINTISAELLRSGKTPRHFITRALLATSNVDDAFRVLKDAGVGAADACSINFTFLADPRQMCYNVEMAPSPDRKNESHLNIKEVPLGEHNYHVNQFDRIRQDQANDLMISSSISRMQTFGAYNPPMSEQDVRHMLGDVSGGVYCVWRENNSCDEVVKTIAVGIFDLSARTISLYSDNPSETEPHCRLPLLYK

[NH3+] C C c 1 c c c ( O ) c ( O ) c 1 . [NH3+] C C C ( = O ) [O-]

O . [NH3+] C C C ( = O ) N C C c 1 c c c ( O ) c ( O ) c 1

MSSGKILPRRQAVPVLYTRGTHYEVGFDMGRTFGSMIKNFLILSKPLNETYLPLYQSPKGRQIYNETLGSVKDSFPQYVRELEGVADGAEVEFHKLFLLHLDEILPQALKHQPRSKNQPTGCSTIIVNQKNCRLLGHTEDALTETLNHYYFVVAHIISDKPQGKYNVKEEHFMSLCYAGHLPGYTMSHNHHGLVFSINTISAELLRSGKTPRHFITRALLATSNVDDAFRVLKDAGVGAADACSINFTFLADPRQMCYNVEMAPSPDRKNESHLNIKEVPLGEHNYHVNQFDRIRQDQANDLMISSSISRMQTFGAYNPPMSEQDVRHMLGDVSGGVYCVWRENNSCDEVVKTIAVGIFDLSARTISLYSDNPSETEPHCRLPLLYK

O = C ( [O-] ) C C = [N+] ( [O-] ) O . O = O . O

[H+] . O = N [O-] . O O . O = C C C ( = O ) [O-] . O = [N+] ( [O-] ) [O-]

MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG

O = [N+] ( [O-] ) [O-] . O = N [O-] . O = C C C ( = O ) [O-] . [H+] . O O

O . O = O . O = C ( [O-] ) C C = [N+] ( [O-] ) O

MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG

O = O . O . O = C ( [O-] ) C C = [N+] ( [O-] ) O

O = N [O-] . O = [N+] ( [O-] ) [O-] . O O . O = C C C ( = O ) [O-] . [H+]

MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG

[H+] . O = [N+] ( [O-] ) [O-] . O = C C C ( = O ) [O-] . O O . O = N [O-]

O . O = O . O = C ( [O-] ) C C = [N+] ( [O-] ) O

MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG

O . * C ( = O ) O [C@H] ( C O C ( = O ) C C C C C ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C

[H+] . * C ( = O ) [O-] . C C C C C C ( = O ) O C [C@@H] ( O ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C

MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ

C C C C C C ( = O ) O C [C@@H] ( O ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C . [H+] . * C ( = O ) [O-]

* C ( = O ) O [C@H] ( C O C ( = O ) C C C C C ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C . O

MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ

O . * C ( = O ) O [C@H] ( C O C ( = O ) C C C C C ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C

C C C C C C ( = O ) O C [C@@H] ( O ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C . [H+] . * C ( = O ) [O-]

MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ

C C C C C C ( = O ) O C [C@@H] ( O ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C . [H+] . * C ( = O ) [O-]

* C ( = O ) O [C@H] ( C O C ( = O ) C C C C C ) C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C . O

MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ

* O [C@H] 1 [C@@H] ( O ) [C@H] ( n 2 c c c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

* O [C@H] 1 [C@@H] ( O ) [C@H] ( c 2 c [nH] c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR

* O [C@H] 1 [C@@H] ( O ) [C@H] ( c 2 c [nH] c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

* O [C@H] 1 [C@@H] ( O ) [C@H] ( n 2 c c c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR

* O [C@H] 1 [C@@H] ( O ) [C@H] ( n 2 c c c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

* O [C@H] 1 [C@@H] ( O ) [C@H] ( c 2 c [nH] c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR

* O [C@H] 1 [C@@H] ( O ) [C@H] ( c 2 c [nH] c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

* O [C@H] 1 [C@@H] ( O ) [C@H] ( n 2 c c c ( = O ) [nH] c 2 = O ) O [C@@H] 1 C O P ( * ) ( = O ) [O-]

MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR

O . C O c 1 c c ( / C = C / C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

C O c 1 c c ( C ( O ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFSPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLAQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTEGGREQGMKQFLDDKSIKPGLQAYKR

C O c 1 c c ( C ( O ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

O . C O c 1 c c ( / C = C / C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFSPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLAQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTEGGREQGMKQFLDDKSIKPGLQAYKR

O . C O c 1 c c ( / C = C / C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

C O c 1 c c ( C ( O ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFSPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLAQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTEGGREQGMKQFLDDKSIKPGLQAYKR

C O c 1 c c ( C ( O ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

O . C O c 1 c c ( / C = C / C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 2 O [C@@H] ( n 3 c n c 4 c ( N ) n c n c 4 3 ) [C@H] ( O ) [C@@H] 2 O P ( = O ) ( [O-] ) [O-] ) c c c 1 O

MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFSPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLAQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTEGGREQGMKQFLDDKSIKPGLQAYKR

C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] . * N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S ) C ( * ) = O . [H+] . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C C ( = O ) [O-]

O = C = O . * N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 C ( = O ) c 2 c ( c c 3 c c ( O ) c c ( O ) c 3 c 2 O ) C C 1 ( O ) C C ( C ) = O ) C ( * ) = O . O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S

MKDNTHSTTLIFFGNEFPNDDLKGLFRCLLRLSKDRRFRQLAAFLEESTLVLKKEVAALPQPLRDLVPHFHTVLPLAELGDFRQGPLGAAMESALLTVLELGMFIGHYEAEGRDWNLLEHNTTLAGLSIGLLAAAGVALSTNLAEVAQNGAECVRVSFRLGVYVSEISRKLEAPQADGTLLSWAHVVTGETKSAIQDELSKYNSESGTPELLKVFISAADKTSVSVSGPPSRMKACFSSSHLLRYSKSFALPVYDGLCHASHLYNEDSINTVINSAESVIPVSRPVQLSLHSSNTGQPFPAATAHELFQAIGKELLTGTIYLDNIIDGIIKRIEGFNPSDLQVETFRTSIVFKSVRAALEGEFPDLEIKITDLIPWAFRDYGPRLPRSFAHSKLAVVGMACRMPGGGNDTELFWEILEQGRDVHTTVPADRFDLSTHYDPSGKTDNAATTPYGNFVDKPGLFDAGFFNMSPKEAEQTDPMQRLALVTAYEALEMAGVVPGRTASSNPKRIGTYYGQASDDWRELNASQNIGTYAVTGGVRAFGNGRINYYFKFPGPSFNVDTACSSGLAAVQVACSALWAGEADTVLAGGLNIITDPDNYAGLGCGHFLSKTGQCKVWDETADGYCRADGIGSVVIKRLEDAEADNDNIIAVVLSAATNHSAEAISITHPHAGNQKDNYRQVIDMAAVNPLDVSYIELHGTGTQAGDAVESESVLDVFAPRSPPRRPDQLLQLGAVKSNIGHGEAAAGIASFLKVLLMYQKNMIPAHIGIHTVINPTIPKDLEQRRVRLTQTNTPWPRLPGKKRIAMVNSFGAHGGNTTVLLEDAPERNKDVARENRSTHTVVISAKSKKSLQANIANLALHLEENPDIDLGDLSYTTCARRIHYTLRVGFAVSSIAGLKEALRKAGEKEALAEVRPTPGDVPPVVFAFTGQGAFYQGIARELFESFSYFRDEVLQLDHIVQRLGFQSIVPVIDGSIGENPSATVSQLSIVVIEIALAHLWTLLLGMQPSAVIGHSLGEYAALVVAGVLSTADGIFLAGRRAQLIEKCCTAGSHAMLSVRASVSEISKLLGNAKYEISCQNTLNDTVIGGTKANLDAARQVLESSSIKCVPVDVPFAFHTEQVDPVLDQLTRVAETVHFKAPSIPIISPLLRSVVFDGKTINSSYLIRATREPVHFAGAIEAAQDLGMVNDKTVWVDVGPHPICASFVRSLIPKARVASSCRRNEDNYATMAKNLVALHLAGCTPVWDEYFRANEKAYNLLTLPKYAWNDVNYWIQYIGTWTLDKAHLKYTGTNGPPQVKPSSSALRTSLIHEIIEETIGEETATLKTVSDLQHPEFLEAVHGHRMNNCGVATSSIWTDMSLTVGEYLYNKLAPGSKVHMNVGELEVLHATVANPAKNCTQNLYLDAHLDLRTQKMSLAWFNVDPATGSKAAESYATGSVRFEADAEKWKSEWERLTHLVLGRIETLESMAKDGQASQLSKALSYALFKNVVDYADHYRGMERVVMHDYEAFCDIKLTPERRGMFHTPPHWIDSVSHLAGLIMNGSDASNTRDYFFVTPGYESFRLLAKLDPDVKYQSYVRMFPLPEANMYGGDLYILQDNQIIGMVGHFKFRRVPRLLMDRFFSAEAASKQSVAASASSAPKTATKHAPLPASKPAQAPAEPTPSSLPTVQAQNTSPPQQVTPSKPAMNGVKTPEEEKPGKADAEGPNGTTSQPEATGVVGQCLQLIANETGQSVNELTPDATFVQLGVDSLMSLVLSEKFRAELGLEVKSSLFLECPTVGDMMDWLEQYC

* N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 C ( = O ) c 2 c ( c c 3 c c ( O ) c c ( O ) c 3 c 2 O ) C C 1 ( O ) C C ( C ) = O ) C ( * ) = O . O = C = O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S . O

C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] . [H+] . * N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S ) C ( * ) = O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C C ( = O ) [O-]

MKDNTHSTTLIFFGNEFPNDDLKGLFRCLLRLSKDRRFRQLAAFLEESTLVLKKEVAALPQPLRDLVPHFHTVLPLAELGDFRQGPLGAAMESALLTVLELGMFIGHYEAEGRDWNLLEHNTTLAGLSIGLLAAAGVALSTNLAEVAQNGAECVRVSFRLGVYVSEISRKLEAPQADGTLLSWAHVVTGETKSAIQDELSKYNSESGTPELLKVFISAADKTSVSVSGPPSRMKACFSSSHLLRYSKSFALPVYDGLCHASHLYNEDSINTVINSAESVIPVSRPVQLSLHSSNTGQPFPAATAHELFQAIGKELLTGTIYLDNIIDGIIKRIEGFNPSDLQVETFRTSIVFKSVRAALEGEFPDLEIKITDLIPWAFRDYGPRLPRSFAHSKLAVVGMACRMPGGGNDTELFWEILEQGRDVHTTVPADRFDLSTHYDPSGKTDNAATTPYGNFVDKPGLFDAGFFNMSPKEAEQTDPMQRLALVTAYEALEMAGVVPGRTASSNPKRIGTYYGQASDDWRELNASQNIGTYAVTGGVRAFGNGRINYYFKFPGPSFNVDTACSSGLAAVQVACSALWAGEADTVLAGGLNIITDPDNYAGLGCGHFLSKTGQCKVWDETADGYCRADGIGSVVIKRLEDAEADNDNIIAVVLSAATNHSAEAISITHPHAGNQKDNYRQVIDMAAVNPLDVSYIELHGTGTQAGDAVESESVLDVFAPRSPPRRPDQLLQLGAVKSNIGHGEAAAGIASFLKVLLMYQKNMIPAHIGIHTVINPTIPKDLEQRRVRLTQTNTPWPRLPGKKRIAMVNSFGAHGGNTTVLLEDAPERNKDVARENRSTHTVVISAKSKKSLQANIANLALHLEENPDIDLGDLSYTTCARRIHYTLRVGFAVSSIAGLKEALRKAGEKEALAEVRPTPGDVPPVVFAFTGQGAFYQGIARELFESFSYFRDEVLQLDHIVQRLGFQSIVPVIDGSIGENPSATVSQLSIVVIEIALAHLWTLLLGMQPSAVIGHSLGEYAALVVAGVLSTADGIFLAGRRAQLIEKCCTAGSHAMLSVRASVSEISKLLGNAKYEISCQNTLNDTVIGGTKANLDAARQVLESSSIKCVPVDVPFAFHTEQVDPVLDQLTRVAETVHFKAPSIPIISPLLRSVVFDGKTINSSYLIRATREPVHFAGAIEAAQDLGMVNDKTVWVDVGPHPICASFVRSLIPKARVASSCRRNEDNYATMAKNLVALHLAGCTPVWDEYFRANEKAYNLLTLPKYAWNDVNYWIQYIGTWTLDKAHLKYTGTNGPPQVKPSSSALRTSLIHEIIEETIGEETATLKTVSDLQHPEFLEAVHGHRMNNCGVATSSIWTDMSLTVGEYLYNKLAPGSKVHMNVGELEVLHATVANPAKNCTQNLYLDAHLDLRTQKMSLAWFNVDPATGSKAAESYATGSVRFEADAEKWKSEWERLTHLVLGRIETLESMAKDGQASQLSKALSYALFKNVVDYADHYRGMERVVMHDYEAFCDIKLTPERRGMFHTPPHWIDSVSHLAGLIMNGSDASNTRDYFFVTPGYESFRLLAKLDPDVKYQSYVRMFPLPEANMYGGDLYILQDNQIIGMVGHFKFRRVPRLLMDRFFSAEAASKQSVAASASSAPKTATKHAPLPASKPAQAPAEPTPSSLPTVQAQNTSPPQQVTPSKPAMNGVKTPEEEKPGKADAEGPNGTTSQPEATGVVGQCLQLIANETGQSVNELTPDATFVQLGVDSLMSLVLSEKFRAELGLEVKSSLFLECPTVGDMMDWLEQYC

* N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S ) C ( * ) = O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C C ( = O ) [O-] . C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] . [H+]

* N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 C ( = O ) c 2 c ( c c 3 c c ( O ) c c ( O ) c 3 c 2 O ) C C 1 ( O ) C C ( C ) = O ) C ( * ) = O . O = C = O . O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S

MKDNTHSTTLIFFGNEFPNDDLKGLFRCLLRLSKDRRFRQLAAFLEESTLVLKKEVAALPQPLRDLVPHFHTVLPLAELGDFRQGPLGAAMESALLTVLELGMFIGHYEAEGRDWNLLEHNTTLAGLSIGLLAAAGVALSTNLAEVAQNGAECVRVSFRLGVYVSEISRKLEAPQADGTLLSWAHVVTGETKSAIQDELSKYNSESGTPELLKVFISAADKTSVSVSGPPSRMKACFSSSHLLRYSKSFALPVYDGLCHASHLYNEDSINTVINSAESVIPVSRPVQLSLHSSNTGQPFPAATAHELFQAIGKELLTGTIYLDNIIDGIIKRIEGFNPSDLQVETFRTSIVFKSVRAALEGEFPDLEIKITDLIPWAFRDYGPRLPRSFAHSKLAVVGMACRMPGGGNDTELFWEILEQGRDVHTTVPADRFDLSTHYDPSGKTDNAATTPYGNFVDKPGLFDAGFFNMSPKEAEQTDPMQRLALVTAYEALEMAGVVPGRTASSNPKRIGTYYGQASDDWRELNASQNIGTYAVTGGVRAFGNGRINYYFKFPGPSFNVDTACSSGLAAVQVACSALWAGEADTVLAGGLNIITDPDNYAGLGCGHFLSKTGQCKVWDETADGYCRADGIGSVVIKRLEDAEADNDNIIAVVLSAATNHSAEAISITHPHAGNQKDNYRQVIDMAAVNPLDVSYIELHGTGTQAGDAVESESVLDVFAPRSPPRRPDQLLQLGAVKSNIGHGEAAAGIASFLKVLLMYQKNMIPAHIGIHTVINPTIPKDLEQRRVRLTQTNTPWPRLPGKKRIAMVNSFGAHGGNTTVLLEDAPERNKDVARENRSTHTVVISAKSKKSLQANIANLALHLEENPDIDLGDLSYTTCARRIHYTLRVGFAVSSIAGLKEALRKAGEKEALAEVRPTPGDVPPVVFAFTGQGAFYQGIARELFESFSYFRDEVLQLDHIVQRLGFQSIVPVIDGSIGENPSATVSQLSIVVIEIALAHLWTLLLGMQPSAVIGHSLGEYAALVVAGVLSTADGIFLAGRRAQLIEKCCTAGSHAMLSVRASVSEISKLLGNAKYEISCQNTLNDTVIGGTKANLDAARQVLESSSIKCVPVDVPFAFHTEQVDPVLDQLTRVAETVHFKAPSIPIISPLLRSVVFDGKTINSSYLIRATREPVHFAGAIEAAQDLGMVNDKTVWVDVGPHPICASFVRSLIPKARVASSCRRNEDNYATMAKNLVALHLAGCTPVWDEYFRANEKAYNLLTLPKYAWNDVNYWIQYIGTWTLDKAHLKYTGTNGPPQVKPSSSALRTSLIHEIIEETIGEETATLKTVSDLQHPEFLEAVHGHRMNNCGVATSSIWTDMSLTVGEYLYNKLAPGSKVHMNVGELEVLHATVANPAKNCTQNLYLDAHLDLRTQKMSLAWFNVDPATGSKAAESYATGSVRFEADAEKWKSEWERLTHLVLGRIETLESMAKDGQASQLSKALSYALFKNVVDYADHYRGMERVVMHDYEAFCDIKLTPERRGMFHTPPHWIDSVSHLAGLIMNGSDASNTRDYFFVTPGYESFRLLAKLDPDVKYQSYVRMFPLPEANMYGGDLYILQDNQIIGMVGHFKFRRVPRLLMDRFFSAEAASKQSVAASASSAPKTATKHAPLPASKPAQAPAEPTPSSLPTVQAQNTSPPQQVTPSKPAMNGVKTPEEEKPGKADAEGPNGTTSQPEATGVVGQCLQLIANETGQSVNELTPDATFVQLGVDSLMSLVLSEKFRAELGLEVKSSLFLECPTVGDMMDWLEQYC

O = C = O . * N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C 1 C ( = O ) c 2 c ( c c 3 c c ( O ) c c ( O ) c 3 c 2 O ) C C 1 ( O ) C C ( C ) = O ) C ( * ) = O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S . O

[H+] . C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] . * N [C@@H] ( C O P ( = O ) ( [O-] ) O C C ( C ) ( C ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S ) C ( * ) = O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S C ( = O ) C C ( = O ) [O-]

MKDNTHSTTLIFFGNEFPNDDLKGLFRCLLRLSKDRRFRQLAAFLEESTLVLKKEVAALPQPLRDLVPHFHTVLPLAELGDFRQGPLGAAMESALLTVLELGMFIGHYEAEGRDWNLLEHNTTLAGLSIGLLAAAGVALSTNLAEVAQNGAECVRVSFRLGVYVSEISRKLEAPQADGTLLSWAHVVTGETKSAIQDELSKYNSESGTPELLKVFISAADKTSVSVSGPPSRMKACFSSSHLLRYSKSFALPVYDGLCHASHLYNEDSINTVINSAESVIPVSRPVQLSLHSSNTGQPFPAATAHELFQAIGKELLTGTIYLDNIIDGIIKRIEGFNPSDLQVETFRTSIVFKSVRAALEGEFPDLEIKITDLIPWAFRDYGPRLPRSFAHSKLAVVGMACRMPGGGNDTELFWEILEQGRDVHTTVPADRFDLSTHYDPSGKTDNAATTPYGNFVDKPGLFDAGFFNMSPKEAEQTDPMQRLALVTAYEALEMAGVVPGRTASSNPKRIGTYYGQASDDWRELNASQNIGTYAVTGGVRAFGNGRINYYFKFPGPSFNVDTACSSGLAAVQVACSALWAGEADTVLAGGLNIITDPDNYAGLGCGHFLSKTGQCKVWDETADGYCRADGIGSVVIKRLEDAEADNDNIIAVVLSAATNHSAEAISITHPHAGNQKDNYRQVIDMAAVNPLDVSYIELHGTGTQAGDAVESESVLDVFAPRSPPRRPDQLLQLGAVKSNIGHGEAAAGIASFLKVLLMYQKNMIPAHIGIHTVINPTIPKDLEQRRVRLTQTNTPWPRLPGKKRIAMVNSFGAHGGNTTVLLEDAPERNKDVARENRSTHTVVISAKSKKSLQANIANLALHLEENPDIDLGDLSYTTCARRIHYTLRVGFAVSSIAGLKEALRKAGEKEALAEVRPTPGDVPPVVFAFTGQGAFYQGIARELFESFSYFRDEVLQLDHIVQRLGFQSIVPVIDGSIGENPSATVSQLSIVVIEIALAHLWTLLLGMQPSAVIGHSLGEYAALVVAGVLSTADGIFLAGRRAQLIEKCCTAGSHAMLSVRASVSEISKLLGNAKYEISCQNTLNDTVIGGTKANLDAARQVLESSSIKCVPVDVPFAFHTEQVDPVLDQLTRVAETVHFKAPSIPIISPLLRSVVFDGKTINSSYLIRATREPVHFAGAIEAAQDLGMVNDKTVWVDVGPHPICASFVRSLIPKARVASSCRRNEDNYATMAKNLVALHLAGCTPVWDEYFRANEKAYNLLTLPKYAWNDVNYWIQYIGTWTLDKAHLKYTGTNGPPQVKPSSSALRTSLIHEIIEETIGEETATLKTVSDLQHPEFLEAVHGHRMNNCGVATSSIWTDMSLTVGEYLYNKLAPGSKVHMNVGELEVLHATVANPAKNCTQNLYLDAHLDLRTQKMSLAWFNVDPATGSKAAESYATGSVRFEADAEKWKSEWERLTHLVLGRIETLESMAKDGQASQLSKALSYALFKNVVDYADHYRGMERVVMHDYEAFCDIKLTPERRGMFHTPPHWIDSVSHLAGLIMNGSDASNTRDYFFVTPGYESFRLLAKLDPDVKYQSYVRMFPLPEANMYGGDLYILQDNQIIGMVGHFKFRRVPRLLMDRFFSAEAASKQSVAASASSAPKTATKHAPLPASKPAQAPAEPTPSSLPTVQAQNTSPPQQVTPSKPAMNGVKTPEEEKPGKADAEGPNGTTSQPEATGVVGQCLQLIANETGQSVNELTPDATFVQLGVDSLMSLVLSEKFRAELGLEVKSSLFLECPTVGDMMDWLEQYC

C c 1 c c 2 c ( c c 1 C ) N ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 1 [nH] c ( = O ) [nH] c ( = O ) c 1 N 2 . O = O . C = C ( C ( = O ) [O-] ) [C@H] 1 C / C = C ( \ C ) C C / C = C ( \ C ) C C 1

O . C c 1 c c 2 n c 3 c ( = O ) [n-] c ( = O ) n c - 3 n ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 2 c c 1 C . C = C 1 C ( = O ) O [C@H] 2 C / C ( C ) = C / C C / C ( C ) = C / C [C@H] 1 2

MEPFTTFSLVASSLILLICWALVKANKPAKNLPPGPPKLPIIGNMHQLESQSPHRVLRKLSRKYGPIMHLQLGQVPTVVISTPRLVEEVVKHHDINFADRPTNTTSQIFYYNNQNVAWSSYGNYWRQIKKIVTLELLSVKKVRSFSSIRAEELTRAVKSVEPSVGSTINFRDLTSQTVNNMVSRATLGDVCKERHILLDTMNDILKTFNSFNVVNFFPSLQFLNVITGKKAKWLKIHKQLDHILENILEEHKSKPKGNQDDEDLIDVLLRVKDAGGQELPITNDNVKAITLEMLTAGTSSSSMTIEWAFCELMRHPEVMKKVQSDVRSAVKGNKVTEDDIQNMHYLKLVVKETLRLHGVPILVPRQNREDCNVLGYHIPAKTKILINAWACGTDPDTWEDPESFIPERFEKSSVSYFGTDFQLIPFGTGRRICPGVNFGIGTVEAVLSNFLYHFDWKLPDGVKPQDIDMTEVTGISTLPKYPLHIVPVSTVSQQK

O . C = C 1 C ( = O ) O [C@H] 2 C / C ( C ) = C / C C / C ( C ) = C / C [C@H] 1 2 . C c 1 c c 2 n c 3 c ( = O ) [n-] c ( = O ) n c - 3 n ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 2 c c 1 C

C = C ( C ( = O ) [O-] ) [C@H] 1 C / C = C ( \ C ) C C / C = C ( \ C ) C C 1 . C c 1 c c 2 c ( c c 1 C ) N ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 1 [nH] c ( = O ) [nH] c ( = O ) c 1 N 2 . O = O

MEPFTTFSLVASSLILLICWALVKANKPAKNLPPGPPKLPIIGNMHQLESQSPHRVLRKLSRKYGPIMHLQLGQVPTVVISTPRLVEEVVKHHDINFADRPTNTTSQIFYYNNQNVAWSSYGNYWRQIKKIVTLELLSVKKVRSFSSIRAEELTRAVKSVEPSVGSTINFRDLTSQTVNNMVSRATLGDVCKERHILLDTMNDILKTFNSFNVVNFFPSLQFLNVITGKKAKWLKIHKQLDHILENILEEHKSKPKGNQDDEDLIDVLLRVKDAGGQELPITNDNVKAITLEMLTAGTSSSSMTIEWAFCELMRHPEVMKKVQSDVRSAVKGNKVTEDDIQNMHYLKLVVKETLRLHGVPILVPRQNREDCNVLGYHIPAKTKILINAWACGTDPDTWEDPESFIPERFEKSSVSYFGTDFQLIPFGTGRRICPGVNFGIGTVEAVLSNFLYHFDWKLPDGVKPQDIDMTEVTGISTLPKYPLHIVPVSTVSQQK

C = C ( C ( = O ) [O-] ) [C@H] 1 C / C = C ( \ C ) C C / C = C ( \ C ) C C 1 . O = O . C c 1 c c 2 c ( c c 1 C ) N ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 1 [nH] c ( = O ) [nH] c ( = O ) c 1 N 2

O . C c 1 c c 2 n c 3 c ( = O ) [n-] c ( = O ) n c - 3 n ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 2 c c 1 C . C = C 1 C ( = O ) O [C@H] 2 C / C ( C ) = C / C C / C ( C ) = C / C [C@H] 1 2

MEPFTTFSLVASSLILLICWALVKANKPAKNLPPGPPKLPIIGNMHQLESQSPHRVLRKLSRKYGPIMHLQLGQVPTVVISTPRLVEEVVKHHDINFADRPTNTTSQIFYYNNQNVAWSSYGNYWRQIKKIVTLELLSVKKVRSFSSIRAEELTRAVKSVEPSVGSTINFRDLTSQTVNNMVSRATLGDVCKERHILLDTMNDILKTFNSFNVVNFFPSLQFLNVITGKKAKWLKIHKQLDHILENILEEHKSKPKGNQDDEDLIDVLLRVKDAGGQELPITNDNVKAITLEMLTAGTSSSSMTIEWAFCELMRHPEVMKKVQSDVRSAVKGNKVTEDDIQNMHYLKLVVKETLRLHGVPILVPRQNREDCNVLGYHIPAKTKILINAWACGTDPDTWEDPESFIPERFEKSSVSYFGTDFQLIPFGTGRRICPGVNFGIGTVEAVLSNFLYHFDWKLPDGVKPQDIDMTEVTGISTLPKYPLHIVPVSTVSQQK

O . C c 1 c c 2 n c 3 c ( = O ) [n-] c ( = O ) n c - 3 n ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 2 c c 1 C . C = C 1 C ( = O ) O [C@H] 2 C / C ( C ) = C / C C / C ( C ) = C / C [C@H] 1 2

O = O . C = C ( C ( = O ) [O-] ) [C@H] 1 C / C = C ( \ C ) C C / C = C ( \ C ) C C 1 . C c 1 c c 2 c ( c c 1 C ) N ( C [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O P ( = O ) ( [O-] ) [O-] ) c 1 [nH] c ( = O ) [nH] c ( = O ) c 1 N 2

MEPFTTFSLVASSLILLICWALVKANKPAKNLPPGPPKLPIIGNMHQLESQSPHRVLRKLSRKYGPIMHLQLGQVPTVVISTPRLVEEVVKHHDINFADRPTNTTSQIFYYNNQNVAWSSYGNYWRQIKKIVTLELLSVKKVRSFSSIRAEELTRAVKSVEPSVGSTINFRDLTSQTVNNMVSRATLGDVCKERHILLDTMNDILKTFNSFNVVNFFPSLQFLNVITGKKAKWLKIHKQLDHILENILEEHKSKPKGNQDDEDLIDVLLRVKDAGGQELPITNDNVKAITLEMLTAGTSSSSMTIEWAFCELMRHPEVMKKVQSDVRSAVKGNKVTEDDIQNMHYLKLVVKETLRLHGVPILVPRQNREDCNVLGYHIPAKTKILINAWACGTDPDTWEDPESFIPERFEKSSVSYFGTDFQLIPFGTGRRICPGVNFGIGTVEAVLSNFLYHFDWKLPDGVKPQDIDMTEVTGISTLPKYPLHIVPVSTVSQQK

* N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O

[H+] . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . * N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O

MEQLLRAQLHTTTLRAFGSSGGGCISEGYAYYTDSGPVFVKVNRRTQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKSKTRQNTVGCGAEGAEPQGVTKFGFHTVTCCGFIPQVNEWQEDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPDLFAGIEIVPALLHGDLWSGNVAEDDQGPVIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHRKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGVMRKLLR

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . [H+] . * N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O

* N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O

MEQLLRAQLHTTTLRAFGSSGGGCISEGYAYYTDSGPVFVKVNRRTQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKSKTRQNTVGCGAEGAEPQGVTKFGFHTVTCCGFIPQVNEWQEDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPDLFAGIEIVPALLHGDLWSGNVAEDDQGPVIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHRKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGVMRKLLR

* N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . * N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O . [H+]

MEQLLRAQLHTTTLRAFGSSGGGCISEGYAYYTDSGPVFVKVNRRTQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKSKTRQNTVGCGAEGAEPQGVTKFGFHTVTCCGFIPQVNEWQEDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPDLFAGIEIVPALLHGDLWSGNVAEDDQGPVIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHRKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGVMRKLLR

[H+] . * N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O

* N [C@@H] ( C C C C [NH2+] C C ( = O ) [C@H] ( O ) [C@H] ( O ) [C@H] ( O ) C O ) C ( * ) = O . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O

MEQLLRAQLHTTTLRAFGSSGGGCISEGYAYYTDSGPVFVKVNRRTQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKSKTRQNTVGCGAEGAEPQGVTKFGFHTVTCCGFIPQVNEWQEDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPDLFAGIEIVPALLHGDLWSGNVAEDDQGPVIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHRKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGVMRKLLR

C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) [O-] . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S

O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O . C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O

MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYSTIKI

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O . C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-]

C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) [O-] . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S

MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYSTIKI

C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) [O-]

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] . O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O

MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYSTIKI

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O . C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) S C C N C ( = O ) C C N C ( = O ) [C@H] ( O ) C ( C ) ( C ) C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-]

C C ( C ) ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) C ( = O ) N C C C ( = O ) N C C S . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 1 O . C C ( C ) C C C C ( C ) C C C C ( C ) C C C C ( C ) C C ( = O ) [O-]

MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYSTIKI

C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O ) c 1 O . C [S+] ( C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O

[H+] . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C S C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) [C@@H] ( O ) [C@H] 1 O . C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O C ) c 1 O

MLFAMQLASASVLPMVLKSAIELDLLEIIRGQDTCMSPTEIASHLPTTNPDAPAMVDRILRLLSCYSVVTCSVRSVDDQRVYGLAPVCKYLTKNQDGVSIAALCLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMSSFEYHGTDPRFNKVFNRGMSDHSTITMKKVFQAYQGFQGLTSLVDVGGGTGATLTMILSKYPTIRCINFDLPHVIEDAPEYPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKLLKNCYDALPNNGKVILAECILPEVPDSSLATKGVVHIDVITVAHNPGGKERTEKEFEALAKAAGFQGFQVFCNAFNTYIIEFSKQICN

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C S C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) [C@@H] ( O ) [C@H] 1 O . [H+] . C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O C ) c 1 O

C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O ) c 1 O . C [S+] ( C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O

MLFAMQLASASVLPMVLKSAIELDLLEIIRGQDTCMSPTEIASHLPTTNPDAPAMVDRILRLLSCYSVVTCSVRSVDDQRVYGLAPVCKYLTKNQDGVSIAALCLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMSSFEYHGTDPRFNKVFNRGMSDHSTITMKKVFQAYQGFQGLTSLVDVGGGTGATLTMILSKYPTIRCINFDLPHVIEDAPEYPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKLLKNCYDALPNNGKVILAECILPEVPDSSLATKGVVHIDVITVAHNPGGKERTEKEFEALAKAAGFQGFQVFCNAFNTYIIEFSKQICN

C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O ) c 1 O . C [S+] ( C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O

N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C S C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) [C@@H] ( O ) [C@H] 1 O . [H+] . C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O C ) c 1 O

MLFAMQLASASVLPMVLKSAIELDLLEIIRGQDTCMSPTEIASHLPTTNPDAPAMVDRILRLLSCYSVVTCSVRSVDDQRVYGLAPVCKYLTKNQDGVSIAALCLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMSSFEYHGTDPRFNKVFNRGMSDHSTITMKKVFQAYQGFQGLTSLVDVGGGTGATLTMILSKYPTIRCINFDLPHVIEDAPEYPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKLLKNCYDALPNNGKVILAECILPEVPDSSLATKGVVHIDVITVAHNPGGKERTEKEFEALAKAAGFQGFQVFCNAFNTYIIEFSKQICN

C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O C ) c 1 O . N c 1 n c n c 2 c 1 n c n 2 [C@@H] 1 O [C@H] ( C S C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) [C@@H] ( O ) [C@H] 1 O . [H+]

C O c 1 c c ( / C = C / C ( = O ) [O-] ) c c ( O ) c 1 O . C [S+] ( C C [C@H] ( [NH3+] ) C ( = O ) [O-] ) C [C@H] 1 O [C@@H] ( n 2 c n c 3 c ( N ) n c n c 3 2 ) [C@H] ( O ) [C@@H] 1 O

MLFAMQLASASVLPMVLKSAIELDLLEIIRGQDTCMSPTEIASHLPTTNPDAPAMVDRILRLLSCYSVVTCSVRSVDDQRVYGLAPVCKYLTKNQDGVSIAALCLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMSSFEYHGTDPRFNKVFNRGMSDHSTITMKKVFQAYQGFQGLTSLVDVGGGTGATLTMILSKYPTIRCINFDLPHVIEDAPEYPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKLLKNCYDALPNNGKVILAECILPEVPDSSLATKGVVHIDVITVAHNPGGKERTEKEFEALAKAAGFQGFQVFCNAFNTYIIEFSKQICN

C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O C ( = O ) C C C C C C C / C = C \ C C C C C C C C . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@@H] ( O ) C O

C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C C ( O ) C O C ( = O ) C C C C C C C / C = C \ C C C C C C C C . * O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O *

MGCLCLYRSTLLTGGLLFLLMLADPAFPAGSRPPVVLVPGDMGNQLEAKLDKPSVVHYVCSKRTDHYFTLWLNLELLLPVIIDCWIDNVRLIYNQTSHTTQFPEGVDVRVPGFGDTFSMEFLDPSKSSVGSYLHTMVESLVSWGYERGKDVRGAPYDWRRAPNENGPYFLALRKMIEEMYQLYGGPVVLVAHSMGNMYMLYFLQHQPQDWKDKYIRAFVALGPPWGGVPKTLRVLASGDNNRIPVIRSLKIRAQQRSAVSTTWLLPYSYTWSPQKVFVRTPKANYTLQDYRQFFQDIGFKDGWSMRQDTEGLVEATVPPGVRLHCLYGTGVPTPESFDYESFPDRDPKIHYGTGDGTVNLQSALHCHTWRGLQKQEVSLQALPGNEHIAMLANTTTLAYLKRVLLGP

* O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O * . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C C ( O ) C O C ( = O ) C C C C C C C / C = C \ C C C C C C C C

C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O C ( = O ) C C C C C C C / C = C \ C C C C C C C C . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@@H] ( O ) C O

MGCLCLYRSTLLTGGLLFLLMLADPAFPAGSRPPVVLVPGDMGNQLEAKLDKPSVVHYVCSKRTDHYFTLWLNLELLLPVIIDCWIDNVRLIYNQTSHTTQFPEGVDVRVPGFGDTFSMEFLDPSKSSVGSYLHTMVESLVSWGYERGKDVRGAPYDWRRAPNENGPYFLALRKMIEEMYQLYGGPVVLVAHSMGNMYMLYFLQHQPQDWKDKYIRAFVALGPPWGGVPKTLRVLASGDNNRIPVIRSLKIRAQQRSAVSTTWLLPYSYTWSPQKVFVRTPKANYTLQDYRQFFQDIGFKDGWSMRQDTEGLVEATVPPGVRLHCLYGTGVPTPESFDYESFPDRDPKIHYGTGDGTVNLQSALHCHTWRGLQKQEVSLQALPGNEHIAMLANTTTLAYLKRVLLGP

C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@@H] ( O ) C O . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O C ( = O ) C C C C C C C / C = C \ C C C C C C C C

* O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O * . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C C ( O ) C O C ( = O ) C C C C C C C / C = C \ C C C C C C C C

MGCLCLYRSTLLTGGLLFLLMLADPAFPAGSRPPVVLVPGDMGNQLEAKLDKPSVVHYVCSKRTDHYFTLWLNLELLLPVIIDCWIDNVRLIYNQTSHTTQFPEGVDVRVPGFGDTFSMEFLDPSKSSVGSYLHTMVESLVSWGYERGKDVRGAPYDWRRAPNENGPYFLALRKMIEEMYQLYGGPVVLVAHSMGNMYMLYFLQHQPQDWKDKYIRAFVALGPPWGGVPKTLRVLASGDNNRIPVIRSLKIRAQQRSAVSTTWLLPYSYTWSPQKVFVRTPKANYTLQDYRQFFQDIGFKDGWSMRQDTEGLVEATVPPGVRLHCLYGTGVPTPESFDYESFPDRDPKIHYGTGDGTVNLQSALHCHTWRGLQKQEVSLQALPGNEHIAMLANTTTLAYLKRVLLGP

* O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O * . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C C ( O ) C O C ( = O ) C C C C C C C / C = C \ C C C C C C C C

C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@H] ( C O P ( = O ) ( [O-] ) O C C [N+] ( C ) ( C ) C ) O C ( = O ) C C C C C C C / C = C \ C C C C C C C C . C C C C C C C C / C = C \ C C C C C C C C ( = O ) O C [C@@H] ( O ) C O

MGCLCLYRSTLLTGGLLFLLMLADPAFPAGSRPPVVLVPGDMGNQLEAKLDKPSVVHYVCSKRTDHYFTLWLNLELLLPVIIDCWIDNVRLIYNQTSHTTQFPEGVDVRVPGFGDTFSMEFLDPSKSSVGSYLHTMVESLVSWGYERGKDVRGAPYDWRRAPNENGPYFLALRKMIEEMYQLYGGPVVLVAHSMGNMYMLYFLQHQPQDWKDKYIRAFVALGPPWGGVPKTLRVLASGDNNRIPVIRSLKIRAQQRSAVSTTWLLPYSYTWSPQKVFVRTPKANYTLQDYRQFFQDIGFKDGWSMRQDTEGLVEATVPPGVRLHCLYGTGVPTPESFDYESFPDRDPKIHYGTGDGTVNLQSALHCHTWRGLQKQEVSLQALPGNEHIAMLANTTTLAYLKRVLLGP

C / C ( C = O ) = C \ C C [C@H] ( C ) / C = C / O

C C 1 = C O C ( O ) [C@H] 2 [C@@H] 1 C C [C@@H] 2 C

MASTANPMQVMKKKLEGKVVIVTGGASGIGQTAARVFAQHGARAVVIADIQSEVGKSVAKSIGDPCCYVQCDVSDEEEVKSMIEWTASAYGGLDMMFSNVGIMSKSAQTVMDLDLLEFDKVMRVNARGMAACLKHAARKMVELGTRGTIICTTTPLSSRGGQSMTDYAMSKHAVMGLVRSASIQLGAHGIRVNCVTPSVVLTPLAQRMGLATPDDFHTHFGNFTSLKGVYLTPEQVAEAVVYLASDDAAFITGHDLVLDGGLLCLPFFAPS

C C 1 = C O C ( O ) [C@H] 2 [C@@H] 1 C C [C@@H] 2 C

C / C ( C = O ) = C \ C C [C@H] ( C ) / C = C / O

MASTANPMQVMKKKLEGKVVIVTGGASGIGQTAARVFAQHGARAVVIADIQSEVGKSVAKSIGDPCCYVQCDVSDEEEVKSMIEWTASAYGGLDMMFSNVGIMSKSAQTVMDLDLLEFDKVMRVNARGMAACLKHAARKMVELGTRGTIICTTTPLSSRGGQSMTDYAMSKHAVMGLVRSASIQLGAHGIRVNCVTPSVVLTPLAQRMGLATPDDFHTHFGNFTSLKGVYLTPEQVAEAVVYLASDDAAFITGHDLVLDGGLLCLPFFAPS

C / C ( C = O ) = C \ C C [C@H] ( C ) / C = C / O

C C 1 = C O C ( O ) [C@H] 2 [C@@H] 1 C C [C@@H] 2 C

MASTANPMQVMKKKLEGKVVIVTGGASGIGQTAARVFAQHGARAVVIADIQSEVGKSVAKSIGDPCCYVQCDVSDEEEVKSMIEWTASAYGGLDMMFSNVGIMSKSAQTVMDLDLLEFDKVMRVNARGMAACLKHAARKMVELGTRGTIICTTTPLSSRGGQSMTDYAMSKHAVMGLVRSASIQLGAHGIRVNCVTPSVVLTPLAQRMGLATPDDFHTHFGNFTSLKGVYLTPEQVAEAVVYLASDDAAFITGHDLVLDGGLLCLPFFAPS

C C 1 = C O C ( O ) [C@H] 2 [C@@H] 1 C C [C@@H] 2 C

C / C ( C = O ) = C \ C C [C@H] ( C ) / C = C / O

MASTANPMQVMKKKLEGKVVIVTGGASGIGQTAARVFAQHGARAVVIADIQSEVGKSVAKSIGDPCCYVQCDVSDEEEVKSMIEWTASAYGGLDMMFSNVGIMSKSAQTVMDLDLLEFDKVMRVNARGMAACLKHAARKMVELGTRGTIICTTTPLSSRGGQSMTDYAMSKHAVMGLVRSASIQLGAHGIRVNCVTPSVVLTPLAQRMGLATPDDFHTHFGNFTSLKGVYLTPEQVAEAVVYLASDDAAFITGHDLVLDGGLLCLPFFAPS

[H+] . O . N c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) n 1

O = c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1 . [NH4+]

MGLKADSWIKKMSLEHGMISPFCEKQIGKDVISYGLSSYGYDIRVGSEFMLFDNKNALIDPKNFDPNNTTKIDASKEGFFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEVCEQSYKDRGGKYQGQVGITLPKILK

[NH4+] . O = c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1

N c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) n 1 . [H+] . O

MGLKADSWIKKMSLEHGMISPFCEKQIGKDVISYGLSSYGYDIRVGSEFMLFDNKNALIDPKNFDPNNTTKIDASKEGFFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEVCEQSYKDRGGKYQGQVGITLPKILK

N c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) n 1 . O . [H+]

[NH4+] . O = c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1

MGLKADSWIKKMSLEHGMISPFCEKQIGKDVISYGLSSYGYDIRVGSEFMLFDNKNALIDPKNFDPNNTTKIDASKEGFFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEVCEQSYKDRGGKYQGQVGITLPKILK

[NH4+] . O = c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1

[H+] . O . N c 1 c c n ( [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) n 1

MGLKADSWIKKMSLEHGMISPFCEKQIGKDVISYGLSSYGYDIRVGSEFMLFDNKNALIDPKNFDPNNTTKIDASKEGFFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEVCEQSYKDRGGKYQGQVGITLPKILK

N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1 . C [C@H] ( O ) [C@@H] 1 O C ( O ) [C@H] ( O ) [C@@H] 1 O

C [C@H] ( O ) [C@@H] 1 O C ( = O ) [C@H] ( O ) [C@@H] 1 O . [H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1

MTGLLNGKVVAITGGVTGIGRAIAIEMARNGAKVVVNHLPSEEQAQLAKELKEEISDGENNVLTIPGDISLPETGRRIVELAVEKFGEINVFVSNAGVCGFREFLEITPETLFQTVNINLNGAFFAIQAAAQQMVKQGKGGSIIGISSISALVGGAHQTHYTPTKAGILSLMQSTACALGKYGIRCNAILPGTISTALNEEDLKDPEKRKYMEGRIPLGRVGDPKDIAGPAIFLASDMSNYVNGAQLLVDGGLFVNLQ

C [C@H] ( O ) [C@@H] 1 O C ( = O ) [C@H] ( O ) [C@@H] 1 O . [H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1

C [C@H] ( O ) [C@@H] 1 O C ( O ) [C@H] ( O ) [C@@H] 1 O . N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1

MTGLLNGKVVAITGGVTGIGRAIAIEMARNGAKVVVNHLPSEEQAQLAKELKEEISDGENNVLTIPGDISLPETGRRIVELAVEKFGEINVFVSNAGVCGFREFLEITPETLFQTVNINLNGAFFAIQAAAQQMVKQGKGGSIIGISSISALVGGAHQTHYTPTKAGILSLMQSTACALGKYGIRCNAILPGTISTALNEEDLKDPEKRKYMEGRIPLGRVGDPKDIAGPAIFLASDMSNYVNGAQLLVDGGLFVNLQ

N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1 . C [C@H] ( O ) [C@@H] 1 O C ( O ) [C@H] ( O ) [C@@H] 1 O

N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1 . [H+] . C [C@H] ( O ) [C@@H] 1 O C ( = O ) [C@H] ( O ) [C@@H] 1 O

MTGLLNGKVVAITGGVTGIGRAIAIEMARNGAKVVVNHLPSEEQAQLAKELKEEISDGENNVLTIPGDISLPETGRRIVELAVEKFGEINVFVSNAGVCGFREFLEITPETLFQTVNINLNGAFFAIQAAAQQMVKQGKGGSIIGISSISALVGGAHQTHYTPTKAGILSLMQSTACALGKYGIRCNAILPGTISTALNEEDLKDPEKRKYMEGRIPLGRVGDPKDIAGPAIFLASDMSNYVNGAQLLVDGGLFVNLQ

C [C@H] ( O ) [C@@H] 1 O C ( = O ) [C@H] ( O ) [C@@H] 1 O . [H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1

C [C@H] ( O ) [C@@H] 1 O C ( O ) [C@H] ( O ) [C@@H] 1 O . N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1

MTGLLNGKVVAITGGVTGIGRAIAIEMARNGAKVVVNHLPSEEQAQLAKELKEEISDGENNVLTIPGDISLPETGRRIVELAVEKFGEINVFVSNAGVCGFREFLEITPETLFQTVNINLNGAFFAIQAAAQQMVKQGKGGSIIGISSISALVGGAHQTHYTPTKAGILSLMQSTACALGKYGIRCNAILPGTISTALNEEDLKDPEKRKYMEGRIPLGRVGDPKDIAGPAIFLASDMSNYVNGAQLLVDGGLFVNLQ

N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1 . O C c 1 c c c n c 1

O = C c 1 c c c n c 1 . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1 . [H+]

MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY

[H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1 . O = C c 1 c c c n c 1

O C c 1 c c c n c 1 . N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1

MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY

N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1 . O C c 1 c c c n c 1

O = C c 1 c c c n c 1 . [H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1

MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY

[H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1 . O = C c 1 c c c n c 1

O C c 1 c c c n c 1 . N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O P ( = O ) ( [O-] ) [O-] ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1

MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY

C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O ) [C@@H] ( O ) [C@H] 1 O . O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O [C@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1

[H+] . O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1 . C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O [C@@H] 2 O [C@@H] ( [C@@H] ( C O ) O [C@@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@H] ( O ) [C@H] 2 O ) [C@@H] ( O ) [C@H] 1 O

MTHTEVVCAVVVTHRRRELLATSLDAVVSQDRKPDHLIVVDNDNDPQVRELVTGQPVPSTYLGSRRNLGGAGGFALGMLHALALGADWIWLADDDGRPADTTVLSTLLSCAHTHSLAEVSPMVCNLDDPQRLAFPLRRGLVWRRLTSELRTDSSSSSGDLLPGIASLFNGALFRADTVDAVGVPDLRLFVRGDEVELHRRLVRSGLPFGTCLTASYLHPCGTDEFKPILGGRMHTQYPDDETKRFFTYRNRGYLLSQPGLRKLLPQEWLRFGWYFLVSRRDLAGLREWIRLRRLGRRERFQR

[H+] . O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1 . C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O [C@@H] 2 O [C@@H] ( [C@@H] ( C O ) O [C@@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@H] ( O ) [C@H] 2 O ) [C@@H] ( O ) [C@H] 1 O

O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O [C@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1 . C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O ) [C@@H] ( O ) [C@H] 1 O

MTHTEVVCAVVVTHRRRELLATSLDAVVSQDRKPDHLIVVDNDNDPQVRELVTGQPVPSTYLGSRRNLGGAGGFALGMLHALALGADWIWLADDDGRPADTTVLSTLLSCAHTHSLAEVSPMVCNLDDPQRLAFPLRRGLVWRRLTSELRTDSSSSSGDLLPGIASLFNGALFRADTVDAVGVPDLRLFVRGDEVELHRRLVRSGLPFGTCLTASYLHPCGTDEFKPILGGRMHTQYPDDETKRFFTYRNRGYLLSQPGLRKLLPQEWLRFGWYFLVSRRDLAGLREWIRLRRLGRRERFQR

C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O ) [C@@H] ( O ) [C@H] 1 O . O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O [C@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1

C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O [C@@H] 2 O [C@@H] ( [C@@H] ( C O ) O [C@@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@H] ( O ) [C@H] 2 O ) [C@@H] ( O ) [C@H] 1 O . [H+] . O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1

MTHTEVVCAVVVTHRRRELLATSLDAVVSQDRKPDHLIVVDNDNDPQVRELVTGQPVPSTYLGSRRNLGGAGGFALGMLHALALGADWIWLADDDGRPADTTVLSTLLSCAHTHSLAEVSPMVCNLDDPQRLAFPLRRGLVWRRLTSELRTDSSSSSGDLLPGIASLFNGALFRADTVDAVGVPDLRLFVRGDEVELHRRLVRSGLPFGTCLTASYLHPCGTDEFKPILGGRMHTQYPDDETKRFFTYRNRGYLLSQPGLRKLLPQEWLRFGWYFLVSRRDLAGLREWIRLRRLGRRERFQR

O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1 . C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O [C@@H] 2 O [C@@H] ( [C@@H] ( C O ) O [C@@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@H] ( O ) [C@H] 2 O ) [C@@H] ( O ) [C@H] 1 O . [H+]

C C ( = O ) N [C@H] 1 [C@@H] ( O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( / C ) C C / C = C ( \ C ) C C C = C ( C ) C ) O [C@H] ( C O ) [C@@H] ( O ) [C@@H] 1 O [C@@H] 1 O [C@@H] ( C ) [C@H] ( O ) [C@@H] ( O ) [C@H] 1 O . O = c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O [C@H] 3 O [C@@H] ( [C@H] ( O ) C O ) [C@H] ( O ) [C@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) [nH] 1

MTHTEVVCAVVVTHRRRELLATSLDAVVSQDRKPDHLIVVDNDNDPQVRELVTGQPVPSTYLGSRRNLGGAGGFALGMLHALALGADWIWLADDDGRPADTTVLSTLLSCAHTHSLAEVSPMVCNLDDPQRLAFPLRRGLVWRRLTSELRTDSSSSSGDLLPGIASLFNGALFRADTVDAVGVPDLRLFVRGDEVELHRRLVRSGLPFGTCLTASYLHPCGTDEFKPILGGRMHTQYPDDETKRFFTYRNRGYLLSQPGLRKLLPQEWLRFGWYFLVSRRDLAGLREWIRLRRLGRRERFQR

[H] * [H] . O O

O . *

MKRTLPTLSALALSMSLALAAGQTQAAETTTNSYWWPEQLDLSPLRQHGSESNPYGADYDYAKAFGSLDLVAVKADIKTVLTTSQDWWPADYGHYGPFFIRMAWHSAGVYRIFDGRGGASGGQQRFEPLNSWPDNVNLDKARRLLWPIKQKYGSKISWADLMVLAGNVSLESMGFKTFGFAGGRTDDWEAERVDWGHEKKWLDNKRHNEKGELAKPLGATQMGLIYVNPEGPNGVPDPLAAARDIRETFGRMAMNDEETVALIAGGHTFGKAHGAHDPAKCVGADPAAAGVEAQGLGWKNKCGKGHSEDTVTSGLEGAWSVSPTQWTMQYLDNLYGFEWVQSKSPAGHIQWIPANGAGDNLVPDAHVAGKRHAPIMFTTDIALKEDPSYREITSRFRKDPKAFELAFAKAWFKLTHRDMGPKTRYLGSDVPAEALIWQDPIPALDHAVIDTNDIAALKSAILASGIAVPELVRTAWASAASFRGTDMRGGANGARLRLEPQRSWEVNNPEELAKVLPKLEKIQKDFNKSLKGGKKVSLADVIVLAGGTAIEQAARSAGYSVTVPFTPGRMDATTAQTDVSSFAVLEPKADAFRNFFSEESYLPPAEALVEKATQLTLSVPEMTALVGGLRVLDANSNKAKHGVFTDKPGNLSNDFFVNLLDMSTRWEKSPREAGLYQGFDRQSGKLRWTATPVDLIFGSHAELRAVAEVYGANDGKDRFVEDFIAAWTKVMNLDRFDI

* . O

[H] * [H] . O O

MKRTLPTLSALALSMSLALAAGQTQAAETTTNSYWWPEQLDLSPLRQHGSESNPYGADYDYAKAFGSLDLVAVKADIKTVLTTSQDWWPADYGHYGPFFIRMAWHSAGVYRIFDGRGGASGGQQRFEPLNSWPDNVNLDKARRLLWPIKQKYGSKISWADLMVLAGNVSLESMGFKTFGFAGGRTDDWEAERVDWGHEKKWLDNKRHNEKGELAKPLGATQMGLIYVNPEGPNGVPDPLAAARDIRETFGRMAMNDEETVALIAGGHTFGKAHGAHDPAKCVGADPAAAGVEAQGLGWKNKCGKGHSEDTVTSGLEGAWSVSPTQWTMQYLDNLYGFEWVQSKSPAGHIQWIPANGAGDNLVPDAHVAGKRHAPIMFTTDIALKEDPSYREITSRFRKDPKAFELAFAKAWFKLTHRDMGPKTRYLGSDVPAEALIWQDPIPALDHAVIDTNDIAALKSAILASGIAVPELVRTAWASAASFRGTDMRGGANGARLRLEPQRSWEVNNPEELAKVLPKLEKIQKDFNKSLKGGKKVSLADVIVLAGGTAIEQAARSAGYSVTVPFTPGRMDATTAQTDVSSFAVLEPKADAFRNFFSEESYLPPAEALVEKATQLTLSVPEMTALVGGLRVLDANSNKAKHGVFTDKPGNLSNDFFVNLLDMSTRWEKSPREAGLYQGFDRQSGKLRWTATPVDLIFGSHAELRAVAEVYGANDGKDRFVEDFIAAWTKVMNLDRFDI

[H] * [H] . O O

* . O

MKRTLPTLSALALSMSLALAAGQTQAAETTTNSYWWPEQLDLSPLRQHGSESNPYGADYDYAKAFGSLDLVAVKADIKTVLTTSQDWWPADYGHYGPFFIRMAWHSAGVYRIFDGRGGASGGQQRFEPLNSWPDNVNLDKARRLLWPIKQKYGSKISWADLMVLAGNVSLESMGFKTFGFAGGRTDDWEAERVDWGHEKKWLDNKRHNEKGELAKPLGATQMGLIYVNPEGPNGVPDPLAAARDIRETFGRMAMNDEETVALIAGGHTFGKAHGAHDPAKCVGADPAAAGVEAQGLGWKNKCGKGHSEDTVTSGLEGAWSVSPTQWTMQYLDNLYGFEWVQSKSPAGHIQWIPANGAGDNLVPDAHVAGKRHAPIMFTTDIALKEDPSYREITSRFRKDPKAFELAFAKAWFKLTHRDMGPKTRYLGSDVPAEALIWQDPIPALDHAVIDTNDIAALKSAILASGIAVPELVRTAWASAASFRGTDMRGGANGARLRLEPQRSWEVNNPEELAKVLPKLEKIQKDFNKSLKGGKKVSLADVIVLAGGTAIEQAARSAGYSVTVPFTPGRMDATTAQTDVSSFAVLEPKADAFRNFFSEESYLPPAEALVEKATQLTLSVPEMTALVGGLRVLDANSNKAKHGVFTDKPGNLSNDFFVNLLDMSTRWEKSPREAGLYQGFDRQSGKLRWTATPVDLIFGSHAELRAVAEVYGANDGKDRFVEDFIAAWTKVMNLDRFDI

* . O

[H] * [H] . O O

MKRTLPTLSALALSMSLALAAGQTQAAETTTNSYWWPEQLDLSPLRQHGSESNPYGADYDYAKAFGSLDLVAVKADIKTVLTTSQDWWPADYGHYGPFFIRMAWHSAGVYRIFDGRGGASGGQQRFEPLNSWPDNVNLDKARRLLWPIKQKYGSKISWADLMVLAGNVSLESMGFKTFGFAGGRTDDWEAERVDWGHEKKWLDNKRHNEKGELAKPLGATQMGLIYVNPEGPNGVPDPLAAARDIRETFGRMAMNDEETVALIAGGHTFGKAHGAHDPAKCVGADPAAAGVEAQGLGWKNKCGKGHSEDTVTSGLEGAWSVSPTQWTMQYLDNLYGFEWVQSKSPAGHIQWIPANGAGDNLVPDAHVAGKRHAPIMFTTDIALKEDPSYREITSRFRKDPKAFELAFAKAWFKLTHRDMGPKTRYLGSDVPAEALIWQDPIPALDHAVIDTNDIAALKSAILASGIAVPELVRTAWASAASFRGTDMRGGANGARLRLEPQRSWEVNNPEELAKVLPKLEKIQKDFNKSLKGGKKVSLADVIVLAGGTAIEQAARSAGYSVTVPFTPGRMDATTAQTDVSSFAVLEPKADAFRNFFSEESYLPPAEALVEKATQLTLSVPEMTALVGGLRVLDANSNKAKHGVFTDKPGNLSNDFFVNLLDMSTRWEKSPREAGLYQGFDRQSGKLRWTATPVDLIFGSHAELRAVAEVYGANDGKDRFVEDFIAAWTKVMNLDRFDI

N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1 . O

O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] . [H+] . N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O ) O 2 ) c ( = O ) [nH] 1

MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ

[H+] . N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O ) O 2 ) c ( = O ) [nH] 1 . O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-]

N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1 . O

MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ

N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1 . O

[H+] . N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O ) O 2 ) c ( = O ) [nH] 1 . O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-]

MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ

[H+] . N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O ) O 2 ) c ( = O ) [nH] 1 . O = P ( [O-] ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-]

O . N c 1 n c 2 c ( n c n 2 [C@H] 2 C [C@H] ( O ) [C@@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) O 2 ) c ( = O ) [nH] 1

MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ

N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1 . O = C ( [O-] ) C C C O

[H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1 . O = C C C C ( = O ) [O-]

MKLLKLAPDVYKFDTAEEFMKYFKVGKGDFILTNEFLYKPFLEKFNDGADAVFQEKYGLGEPSDEMINNIIKDIGDKQYNRIIAVGGGSVIDIAKILSLKYTDDSLDLFEGKVPLVKNKELIIVPTTCGTGSEVTNVSVAELKRRHTKKGIASDELYATYAVLVPEFIKGLPYKFFVTSSVDALIHATEAYVSPNANPYTDMFSVKAMELILNGYMQMVEKGNDYRVEIIEDFVIGSNYAGIAFGNAGVGAVHALSYPIGGNYHVPHGEANYLFFTEIFKTYYEKNPNGKIKDVNKLLAGILKCDESEAYDSLSQLLDKLLSRKPLREYGMKEEEIETFADSVIEGQQRLLVNNYEPFSREDIVNTYKKLY

[H+] . O = C C C C ( = O ) [O-] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1

O = C ( [O-] ) C C C O . N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1

MKLLKLAPDVYKFDTAEEFMKYFKVGKGDFILTNEFLYKPFLEKFNDGADAVFQEKYGLGEPSDEMINNIIKDIGDKQYNRIIAVGGGSVIDIAKILSLKYTDDSLDLFEGKVPLVKNKELIIVPTTCGTGSEVTNVSVAELKRRHTKKGIASDELYATYAVLVPEFIKGLPYKFFVTSSVDALIHATEAYVSPNANPYTDMFSVKAMELILNGYMQMVEKGNDYRVEIIEDFVIGSNYAGIAFGNAGVGAVHALSYPIGGNYHVPHGEANYLFFTEIFKTYYEKNPNGKIKDVNKLLAGILKCDESEAYDSLSQLLDKLLSRKPLREYGMKEEEIETFADSVIEGQQRLLVNNYEPFSREDIVNTYKKLY

O = C ( [O-] ) C C C O . N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1

O = C C C C ( = O ) [O-] . [H+] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1

MKLLKLAPDVYKFDTAEEFMKYFKVGKGDFILTNEFLYKPFLEKFNDGADAVFQEKYGLGEPSDEMINNIIKDIGDKQYNRIIAVGGGSVIDIAKILSLKYTDDSLDLFEGKVPLVKNKELIIVPTTCGTGSEVTNVSVAELKRRHTKKGIASDELYATYAVLVPEFIKGLPYKFFVTSSVDALIHATEAYVSPNANPYTDMFSVKAMELILNGYMQMVEKGNDYRVEIIEDFVIGSNYAGIAFGNAGVGAVHALSYPIGGNYHVPHGEANYLFFTEIFKTYYEKNPNGKIKDVNKLLAGILKCDESEAYDSLSQLLDKLLSRKPLREYGMKEEEIETFADSVIEGQQRLLVNNYEPFSREDIVNTYKKLY

O = C C C C ( = O ) [O-] . N C ( = O ) C 1 = C N ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) C = C C 1 . [H+]

N C ( = O ) c 1 c c c [n+] ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O C [C@H] 3 O [C@@H] ( n 4 c n c 5 c ( N ) n c n c 5 4 ) [C@H] ( O ) [C@@H] 3 O ) [C@@H] ( O ) [C@H] 2 O ) c 1 . O = C ( [O-] ) C C C O

MKLLKLAPDVYKFDTAEEFMKYFKVGKGDFILTNEFLYKPFLEKFNDGADAVFQEKYGLGEPSDEMINNIIKDIGDKQYNRIIAVGGGSVIDIAKILSLKYTDDSLDLFEGKVPLVKNKELIIVPTTCGTGSEVTNVSVAELKRRHTKKGIASDELYATYAVLVPEFIKGLPYKFFVTSSVDALIHATEAYVSPNANPYTDMFSVKAMELILNGYMQMVEKGNDYRVEIIEDFVIGSNYAGIAFGNAGVGAVHALSYPIGGNYHVPHGEANYLFFTEIFKTYYEKNPNGKIKDVNKLLAGILKCDESEAYDSLSQLLDKLLSRKPLREYGMKEEEIETFADSVIEGQQRLLVNNYEPFSREDIVNTYKKLY

O . N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1

[H+] . N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1 . O = P ( [O-] ) ( [O-] ) O

MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAALWMEEGLPAQNAPGTL

[H+] . O = P ( [O-] ) ( [O-] ) O . N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1

N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1 . O

MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAALWMEEGLPAQNAPGTL

N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1 . O

[H+] . O = P ( [O-] ) ( [O-] ) O . N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1

MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAALWMEEGLPAQNAPGTL

O = P ( [O-] ) ( [O-] ) O . [H+] . N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1

N c 1 c c n ( [C@@H] 2 O [C@H] ( C O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) O P ( = O ) ( [O-] ) [O-] ) [C@@H] ( O ) [C@H] 2 O ) c ( = O ) n 1 . O

MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAALWMEEGLPAQNAPGTL