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CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many violations of Lipinski's Rule of Five are there for this compound, using the HBA_LIPINSKI and HBD_LIPINSKI counts? | 0 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many hydrogen bond acceptors does this compound have? | 4 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Determine if this drug is administered as a racemic mixture, a single stereoisomer, an achiral molecule, or has an unknown chirality. | Racemic mixture |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many hydrogen bond donors are there in this compound, calculated according to Lipinski's original rules (i.e., counting NH and OH groups)? | 1 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is this compound a small molecule polymer, such as polystyrene sulfonate? | No |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is this molecule characterized by a small molecular structure or a protein sequence? | It has a small molecule structure. |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the calculated ALogP value for this compound? | 1.93 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the molecular formula of this compound, including any salt that it may have? | C17H23NO3 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is it known whether this drug is administered parenterally? | Yes |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Please provide a description of this drug's mechanism of action. | Muscarinic acetylcholine receptor M1 antagonist |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Determine if this molecule is inorganic, meaning it contains only metal atoms and fewer than two carbon atoms. | No |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the highest development stage achieved for this compound across all indications? Please respond with Approved, Phase 3 Clinical Trials, Phase 2 Clinical Trials, Phase 1 Clinical Trials, Early Phase 1 Clinical Trials, or Clinical Phase Unknown. | Approved |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is it known whether this drug is applied topically? | Yes |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is there a black box warning associated with this drug? | No |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many heavy (non-hydrogen) atoms does this compound have? | 21 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is it known if this drug is the first approved in its class, regardless of the indication or route of administration, acting on a specific target? | No |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the polar surface area (PSA) value of this compound? | 49.77 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is this drug used for therapeutic purposes, rather than for imaging, additives, or other non-therapeutic applications? | Yes |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Please provide a description of this drug's mechanism of action. | Muscarinic acetylcholine receptor M2 antagonist |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Has this approved drug been withdrawn due to toxicity reasons for all indications, populations, and doses in at least one country (not necessarily the US)? | No |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many violations of Lipinski's Rule of Five (using HBA and HBD definitions) are there for this compound? | 0 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many aromatic rings does this compound have? | 1 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the molecular weight of this compound's parent molecule? | 289.38 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Determine the type of availability for this drug. | prescription only |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is this compound an acid, a base, or neutral? | BASE |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many hydrogen bond acceptors are there in this compound, calculated according to Lipinski's original rules (i.e., counting N and O atoms)? | 4 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is it known whether this drug is taken orally? | Yes |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Is the drug administered in this specific form, such as a particular salt? | Yes |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Determine if this compound is a prodrug. | No |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Please provide a description of this drug's mechanism of action. | Muscarinic acetylcholine receptor M3 antagonist |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | How many hydrogen bond donors does this compound have? | 1 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the first recorded year of approval for this drug? | 1960 |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the definition of this compound's USAN stem? | atropine derivatives |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | What is the classification of this molecule? Please respond with Small Molecule, Protein, Antibody, Oligosaccharide, Oligonucleotide, Cell, Enzyme, Gene, or Unknown. | Small molecule |
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 | Which USAN substem can this drug or clinical candidate name be matched with? | -trop- |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Does this compound satisfy the rule-of-three criteria? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many violations of Lipinski's Rule of Five are there for this compound, using the HBA_LIPINSKI and HBD_LIPINSKI counts? | 0 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Determine if this drug is administered as a racemic mixture, a single stereoisomer, an achiral molecule, or has an unknown chirality. | Racemic mixture |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is it known whether this drug is administered parenterally? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many hydrogen bond donors are there in this compound, calculated according to Lipinski's original rules (i.e., counting NH and OH groups)? | 1 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the molecular weight of this compound's parent molecule? | 284.36 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is this compound a small molecule polymer, such as polystyrene sulfonate? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the molecular formula of this compound, including any salt that it may have? | C17H20N2O2 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is this molecule characterized by a small molecular structure or a protein sequence? | It has a small molecule structure. |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Determine if this molecule is inorganic, meaning it contains only metal atoms and fewer than two carbon atoms. | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the highest development stage achieved for this compound across all indications? Please respond with Approved, Phase 3 Clinical Trials, Phase 2 Clinical Trials, Phase 1 Clinical Trials, Early Phase 1 Clinical Trials, or Clinical Phase Unknown. | Approved |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is it known whether this drug is applied topically? | Yes |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is there a black box warning associated with this drug? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many heavy (non-hydrogen) atoms does this compound have? | 21 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many aromatic rings does this compound have? | 2 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many rotatable bonds does this compound have? | 6 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is it known if this drug is the first approved in its class, regardless of the indication or route of administration, acting on a specific target? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many hydrogen bond acceptors does this compound have? | 3 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Which USAN substem can this drug or clinical candidate name be matched with? | trop- |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the polar surface area (PSA) value of this compound? | 53.43 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is this drug used for therapeutic purposes, rather than for imaging, additives, or other non-therapeutic applications? | Yes |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Has this approved drug been withdrawn due to toxicity reasons for all indications, populations, and doses in at least one country (not necessarily the US)? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the calculated ALogP value for this compound? | 2.21 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many violations of Lipinski's Rule of Five (using HBA and HBD definitions) are there for this compound? | 0 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is it known whether this drug is taken orally? | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is this compound an acid, a base, or neutral? | NEUTRAL |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Determine the type of availability for this drug. | prescription only |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many hydrogen bond acceptors are there in this compound, calculated according to Lipinski's original rules (i.e., counting N and O atoms)? | 4 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Is the drug administered in this specific form, such as a particular salt? | Yes |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Determine if this compound is a prodrug. | No |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | Please provide a description of this drug's mechanism of action. | Muscarinic acetylcholine receptor M3 antagonist |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | How many hydrogen bond donors does this compound have? | 1 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the first recorded year of approval for this drug? | 1960 |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the definition of this compound's USAN stem? | atropine derivatives |
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 | What is the classification of this molecule? Please respond with Small Molecule, Protein, Antibody, Oligosaccharide, Oligonucleotide, Cell, Enzyme, Gene, or Unknown. | Small molecule |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Determine if this drug is administered as a racemic mixture, a single stereoisomer, an achiral molecule, or has an unknown chirality. | Single stereoisomer |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Does this compound satisfy the rule-of-three criteria? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many violations of Lipinski's Rule of Five are there for this compound, using the HBA_LIPINSKI and HBD_LIPINSKI counts? | 0 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is it known whether this drug is administered parenterally? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is it known whether this drug is applied topically? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is this compound a small molecule polymer, such as polystyrene sulfonate? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the molecular weight of this compound's parent molecule? | 362.47 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is this molecule characterized by a small molecular structure or a protein sequence? | It has a small molecule structure. |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the polar surface area (PSA) value of this compound? | 32.78 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many hydrogen bond donors does this compound have? | 0 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Determine if this molecule is inorganic, meaning it contains only metal atoms and fewer than two carbon atoms. | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the highest development stage achieved for this compound across all indications? Please respond with Approved, Phase 3 Clinical Trials, Phase 2 Clinical Trials, Phase 1 Clinical Trials, Early Phase 1 Clinical Trials, or Clinical Phase Unknown. | Approved |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the calculated ALogP value for this compound? | 3.86 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is there a black box warning associated with this drug? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many aromatic rings does this compound have? | 2 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many heavy (non-hydrogen) atoms does this compound have? | 27 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is it known if this drug is the first approved in its class, regardless of the indication or route of administration, acting on a specific target? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many hydrogen bond acceptors does this compound have? | 3 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many hydrogen bond donors are there in this compound, calculated according to Lipinski's original rules (i.e., counting NH and OH groups)? | 0 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is this drug used for therapeutic purposes, rather than for imaging, additives, or other non-therapeutic applications? | Yes |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the definition of this compound's USAN stem? | muscarinic receptor antagonists |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Please provide a description of this drug's mechanism of action. | Muscarinic acetylcholine receptor M2 antagonist |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Which USAN substem can this drug or clinical candidate name be matched with? | -fenacin |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the first recorded year of approval for this drug? | 2004 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | What is the molecular formula of this compound, including any salt that it may have? | C27H32N2O6 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Has this approved drug been withdrawn due to toxicity reasons for all indications, populations, and doses in at least one country (not necessarily the US)? | No |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many violations of Lipinski's Rule of Five (using HBA and HBD definitions) are there for this compound? | 0 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Determine the type of availability for this drug. | prescription only |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | How many rotatable bonds does this compound have? | 2 |
O=C(O)CCC(=O)O.O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 | Is this compound an acid, a base, or neutral? | BASE |