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C0062934

An enzyme that catalyzes the demethylation of L-homocysteine to L-METHIONINE.

Homocysteine Transmethylase|Transmethylase, Homocysteine|Homocysteine methyltransferase (substance)|Methyltransferase, S-Adenosylmethionine Homocysteine|Homocysteine Methyltransferase, S-Methylmethionine|S-Methylmethionine Homocysteine Methyltransferase|S-Methyltransferase, Homocysteine|Methyltransferase, Homocysteine|S Adenosylmethionine Homocysteine Methyltransferase|S Methylmethionine Homocysteine Methyltransferase|Homocysteine S Methyltransferase|Methyltransferase, S-Methylmethionine Homocysteine|Homocysteine Methyltransferase|Homocysteine methyltransferase|Homocysteine Methyltransferase, S-Adenosylmethionine|S-Adenosylmethionine Homocysteine Methyltransferase

Homocysteine S-Methyltransferase

C0069676

Osteopontin (314 aa, ~35 kDa) is encoded by the human SPP1 gene. This protein is involved in the regulation of both tissue mineralization and cell-cell signaling.

Osteopontin (substance)|Sialoprotein 1, Bone|Bone Sialoprotein 1|osteopontin|Osteopontin|Sialoprotein 1|Bone Sialoprotein I|Sialoprotein I, Bone|Secreted Phosphoprotein 1

osteopontin

C0027651

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

NEOPLASMS|Tumour, NOS|Neoplasia|tumor|tumors|neoplastic growth|Neoplasm|Tumor, NOS|NEOPLASMS, NOS|Other Neoplasm|neoplasm|Oncological abnormality|neoplastic disease|Neoplasm (morphologic abnormality)|TUMOR|neoplasms|NEOPLASM|Neoplasias|tumours|Neoplastic Growth|Neoplastic Disease|NEOPLASM (NOS)|tumour|Tumour|neoplasias|NEOPLASIA|NEOPLASM NOS|Neoplasm, NOS|Tumors|Tumor|neoplastic syndrome|Neoplasms|Oncology|neoplasia

Neoplasms

C0911543

CP172732

C0911543

CP172732

C0033684

Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.

Protein (substance)|Protein|gene product|protein|PROTEINS|proteins|PROTEIN|Protein-containing product|Proteins|Protein, NOS|Protein (NOS)|Product containing protein (product)

Proteins

C0041904

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Up-Regulation|Up-Regulation (Physiology)|up regulation|up-regulation|Up Regulation|Upregulation|upregulation

Up-Regulation (Physiology)

C0016219

A group of 4-keto-FLAVONOIDS.

Flavones|flavone|2-Phenyl-2-Ene-Benzopyran-4-One Compounds|flavones

Flavones

C0001674

The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.

adsorption|Adsorptions|Adsorption

Adsorption (natural process)

C0729650

constituent|Constituents (substance)|constituents

Constituents

C1601799

PO4(3-).

PHOSPHATE|phosphate ion|Phosphate ion|Phosphate Ion|PHOSPHATE ION|Phosphate|phosphate|Phosphate (substance)|PO4 - Phosphate|inorganic phosphate

phosphate ion

C0025746

A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.

Blue N, Methylene|Blue, Swiss|Azul de Metileno|Methylthioninium Chloride|Methylthioninium chloride stain|Methylthioninii Chloridum|Methylene blue stain (substance)|Methylenium ceruleum|blue methylene staining|Methylenum Caeruleum|Methylene Blue|Product containing methylene blue stain (medicinal product)|Blu di Metilene|Lowacryl blue 9|Methylthioninium chloride|Methylthioninium chloride-containing product|Colour Index No. 52015|Cloruro de metiltioninio|Azul de metileno|CI Basic Blue 9|METHYLENE BLUE|methylthioninium chloride|methylene blue|Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride|methylene blue stain|Methylthionine Chloride|MB|Schultz No. 1038|Basic Blue 9|blue methylene|Tetramethylthionine Chloride Trihydrate|Swiss Blue|Blue 9, Basic|Methylene blue stain-containing product|Methylene blue stain|Blue, Methylene|C.I. basic blue 9|Methylene blue|Methylene Blue N

methylene blue

C0060600

Fraction of coal ash collected at the top section of chimneys.

Ash, Fly

Fly Ash

C0599444

The portion of the cell soma (neuronal cell body) that excludes the nucleus. [GOC:jl]

bodies cells|bodies cell|somas|neural cell body|soma|neuronal cell soma|body cell|neuronal cell body|Cell Body|body cells|Perikaryon|Soma of neuron|Cell body of neuron|cell body|neuron cell body|perikaryon

Cell body of neuron

C1441759

Thin film method

C0005456

The parts of a macromolecule that directly participate in its specific combination with another molecule.

RECEPTOR SITES|binding sites|Binding Site|reactive site|Site, Combining|Combining Site|Sites, Binding|Binding Sites|Sites, Combining|Site, Binding|Combining Sites|Binding site, NOS|Binding sites (Biochemistry)|receptor site|Receptor site, NOS|binding site|receptor sites

Binding Sites

C0003075

Negatively charged atoms, radicals or groups of atoms which travel to the anode or positive pole during electrolysis.

anion|anions|Anion|Anions|negatively charged particle

Anions

C0728940

The act of cutting out; the surgical removal of part or all of a structure or organ.

Abscission|Extirpation|resection|Surgical removal - action|removal surgical procedure|ectomy|Incision and removal, NOS|removals|removal surgical|EXCISIONS|Abscission, NOS|-ectomy|Excisional|Surgical Removal|Surgical Resection|Removal|excision|removal|procedures removal surgical|Surgical removal (procedure)|removal technique|Incision of T site to remove M|Excision (procedure)|Resection|Excision - action|Excision, NOS|Resection, NOS|Excision procedure|Incision and removal|Surgical removal - action (qualifier value)|Excision, NOS (-ectomy)|EXCISION|surgical excision|removal techniques|Surgical removal|surgical resection|procedure removal surgical|Excision|Extirpation, NOS|SR - Surgical removal|Removal, NOS|Excision - action (qualifier value)|surgical removal

Excision

C0072171

1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-|Apaxifylline|propentofylline|Propentofylline|PROPENTOFYLLINE|1-(5'-oxohexyl)-3-methyl-7-propylxanthine|3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione

propentofylline

C0031117

A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs.

PERIPHERAL NEUROPATHY|Peripheral Neuropathy|peripheral neuropathy|Peripheral nerve damage|Peripheral neuropathy|Peripheral neuritis|Peripheral Nerve Disorder

Peripheral Neuropathy

C0030193

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

painful|PAIN|Pain, NOS|Dolor|Painful|pain|Pain|pains|Part hurts|sense of pain|Pain NOS|Pain observations|Unspecified Pain|Pain (finding)|TYPES OF PAIN

Pain

C0042679

An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)

LEUROCRISTINE|Vincristina|VINCRISTINE|vincrystine|Vincristinum|vincristine|Vincristin|vinCRIStine|VCR|oxovincaleukoblastine|lcr|Vincaleukoblastine, 22-oxo-|22-Oxovincaleukoblastine|LCR|Leurocristine|Vincrystine|Product containing vincristine (medicinal product)|vcr|leurocristine|22-Oxovincaleukoblastin|Vincristine-containing product|Vincristine|Vincristine (substance)

vincristine

C0205099

A point or area that is approximately central within some larger region or structure.

centre|Central (qualifier value)|centered|center|CENTRAL|centers|central location|central|centres|Center|Centre|Central

Central

C0871125

The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse. [GOC:dph, PMID:10341260]

prepulse inhibition|Prepulse Inhibition|pre-pulse inhibition|Inhibition, Prepulse|PPI

prepulse inhibition activity

C0234173

An involuntary, primal response in the neonate to loud noise or the feeling of falling. The response is characterized by the infant's arms symmetrically spreading out to the side and then back to the midline, and involuntarily flexing the fingers and toes.

Moro reflex (observable entity)|Reflex, Moro|Moro reflex|reflex startle|Infant startle reflex|Embrace reflex|startle reflex|Startle Reflex|Startle reflex|moro reflex|Moro Reflex

Reflex, Moro

C0900627

Disks large homolog 4 (724 aa, ~80 kDa) is encoded by the human DLG4 gene. This protein is involved in synaptic signal transmission.

Disks Large Homolog 4|PSD-95|Postsynaptic Density-95|Presynaptic Density Protein 95|SAP-90|Synapse-Associated Protein 90|SAP90

Disks Large Homolog 4, Human

C0900627

Disks large homolog 4 (724 aa, ~80 kDa) is encoded by the human DLG4 gene. This protein is involved in synaptic signal transmission.

Disks Large Homolog 4|PSD-95|Postsynaptic Density-95|Presynaptic Density Protein 95|SAP-90|Synapse-Associated Protein 90|SAP90

Disks Large Homolog 4, Human

C1511501

An animal in a study that does not receive the treatment being tested. Comparing the health of control animals with the health of treated animals allows researchers to evaluate the effects of a treatment more accurately.

control animal

Control Animal

C0107103

A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)

BDNF|brain derived neurotrophic factor|Brain-Derived Neurotrophic Factor|brain derived neurotrophic factor (BDNF)|Brain Derived Neurotrophic Factor|bdnf|Neurotrophic Factor, Brain-Derived|Factor, Brain-Derived Neurotrophic

brain-derived neurotrophic factor

C0220839

glutamate|Glutamate|Glu|Glutamate (substance)|L Glutamate|l-glutamate|L-Glutamate

glutamate

C0234073

Neuronal excitation, function|Neuronal excitation, function (observable entity)|Neuronal excitation|Excitation, neuronal

Neuronal excitation

C0175202

Structure of hippocampal formation (body structure)|Structure of hippocampal formation|Hippocampal Formations|Hippocampus (Crosby)|Hippocampal Formation|hippocampal formation|Formation, Hippocampal|Formations, Hippocampal|Formatio hippocampi|Hippocampal formation

Structure of hippocampal formation

C0022471

(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.

Acid, Digenic|Acid, Kainic|acid kainic|Kainic acid|2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid|KAINIC ACID|3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-|L-alpha-Kainic Acid|Digenic Acid|kainic acid|Kainic Acid

Kainic Acid

C0270736

A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)

Essential Tremor, Benign|essential benign tremor|Benign Essential Tremor|Essential Tremor|BENIGN ESSENTIAL TREMOR SYNDROME|Essential tremor (disorder)|Benign Essential Tremors|PRESENILE TREMOR SYNDROME|Tremors, Essential|benign essential tremor syndrome|Tremor, Essential|Essential tremor|Essential Tremors, Benign|physiological tremor|Essential Tremors|Tremor, Benign Essential|Tremor, essential|tremor essential|Tremors, Benign Essential|benign essential tremor|Benign essential tremor|benign essential tremors|essential tremor|essential benign tremors|Tremor, physiological|essential tremors

Essential Tremor

C0040822

Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

quiver|tremor|Tremor, NOS|tremors|quivers|Trembled|Has a tremor|Tremor|shake|shakes|Shaking/Tremors|Shaking all over|the shakes|shaking|Tremor NOS|TREMOR|Tremor (finding)|quivering|d tremors|Tremors/Shaking|Involuntary shaking|Shaking|Shakes|The shakes|SHAKING|Tremors|TREMORS

Tremor

C0206518

Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.

gaba receptors|acid gamma aminobutyric receptors|Receptor, GABA|Receptor, gamma-Aminobutyric Acid|Receptors, gamma Aminobutyric Acid|gamma-Aminobutyric Acid Receptors|GABA receptors|GABA Receptor|GABA--Receptors|GABA Receptors|Receptors, GABA|Receptors, gamma-Aminobutyric Acid|GABA receptor|gaba receptor|gamma Aminobutyric Acid Receptors|gamma Aminobutyric Acid Receptor|gamma-Aminobutyric Acid Receptor

GABA Receptor

C0596611

The result of any gain, loss or alteration of the sequences comprising a gene, including all sequences transcribed into RNA.

gene mutations|gene mutation|mutation gene|genes mutation|Gene Mutation|Gene Mutation Type|Gene Alteration|Sequence Alteration|DNA Sequence Alteration|DNA Alteration

Gene Mutation

C0393615

Familial Tremor|Hereditary essential tremor (disorder)|tremor familial|Tremor, Familial|FAMILIAL TREMOR|Familial tremor|Tremors, Familial|Heredofamilial tremor|benign familial tremors|familial tremors|TREMOR, HEREDITARY, BENIGN|familial tremor|benign familial tremor|Familial Tremors|Hereditary essential tremor|Hereditary Essential Tremor

Familial Tremor

C1412554

ARSB|ARYLSULFATASE B|ARSB gene|arylsulfatase B

ARSB gene

C1412554

ARSB|ARYLSULFATASE B|ARSB gene|arylsulfatase B

ARSB gene

C0028936

Ovoid body resting on the CRIBRIFORM PLATE of the ethmoid bone where the OLFACTORY NERVE terminates. The olfactory bulb contains several types of nerve cells including the mitral cells, on whose DENDRITES the olfactory nerve synapses, forming the olfactory glomeruli. The accessory olfactory bulb, which receives the projection from the VOMERONASAL ORGAN via the vomeronasal nerve, is also included here.

Olfactory Bulb|olfactory bulbs|Main Olfactory Bulb|Olfactory Bulb, Main|Structure of olfactory bulb (body structure)|OLFACTORY BULB|Olfactorius, Bulbus|Bulb, Olfactory|Bulb, Main Olfactory|BRAIN, OLFACTORY BULB|Bulbus Olfactorius|Bulbus olfactorius|olfactory bulb|Bulbs, Main Olfactory|Olfactory Bulbs|Bulbs, Olfactory|Structure of olfactory bulb|Olfactory Bulbs, Main|Main Olfactory Bulbs|Olfactory bulb

Structure of olfactory bulb

C0597879

immunoreactivity

immunoreactivity

C0235678

Vaginal odour, NOS|vaginal odour|odor vaginal|VAGINAL ODOR|Vaginal odor, NOS|Vaginal odor (finding)|odours vaginal|vaginal odor|odors vaginal|Vaginal odour

Vaginal odor

C0720417

brand of ferrous fumarate

ferret|Ferret brand

Ferret brand of ferrous fumarate

C0031849

A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.

PHYSOSTIGMINE|Physostigmine-containing product|Physostigmine (substance)|Physostigmine|Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-|physostigmine|Product containing physostigmine (medicinal product)

physostigmine

C0034830

One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.

Receptors, Nicotinic|Nicotinic acetylcholine receptor|receptor nicotinic|Nicotinic receptors|Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptors|Acetylcholine Receptors, Nicotinic|acetylcholine nicotinic receptor|Nicotinic Receptor|Receptor, Nicotinic|Nicotinic receptor|Acetylcholine Receptor, Nicotinic|Nicotinic receptor (substance)|nicotinic receptors|Receptor, Nicotinic Acetylcholine|nicotinic receptor|Nicotinic receptor site|Receptors, Nicotinic Acetylcholine|Nicotinic Receptors

Nicotinic Receptors

C0376702

CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CHLOROCEBUS AETHIOPS).)

COS-1|Cells, COS|COS Cells|COS Cell|cos cells|cos cell|Cell, COS

COS Cells

C0001041

A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

acetylcholine|Acetylcholine (substance)|2-(Acetyloxy)-N,N,N-trimethylethanaminium|O-Acetylcholine|ACETYLCHOLINE|Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-|ACh|Choline acetate|Acetylcholine preparation|Product containing acetylcholine (medicinal product)|Acetylcholine|Acetylcholine-containing product

acetylcholine

C0020505

Ingestion of a greater than optimal quantity of food.

hyperalimentation|Hyperalimentation NOS|Excessive eating, NOS|Overeating (finding)|HYPERPHAGIA|Hyperphagia|Excessive eating - polyphagia|POLYPHAGIA|Gluttony|Polyphagia|gluttony|Hyperalimentation, NOS|Excessive eating|Excessive oral food intake|excessive eating|Overeats|polyphagia|Polyphagias|Overeating, NOS|hyperphagia|Voracious appetite|Overeating|Excessive eating - polyphagia (finding)|overeat|overeating|over eating

Hyperphagia

C0021516

to supply an organ or a body part with nerves.

Innervation|innervation|Innervation (attribute)

nerve supply

C0037267

The outer covering of the body composed of the SKIN and the skin appendages, which are the HAIR, the NAILS; and the SEBACEOUS GLANDS and the SWEAT GLANDS and their ducts.

integumentary systems|integumentary system|integument|Integumentary System|system integumentary|Organ System, Dermatologic|The integument|Integumentary system structure|INTEGUMENTARY SYSTEM|Dermatologic Body System|Integumentary system, NOS|Structure of integumentary system (body structure)|Integumentum commune|Integumentary system|Dermatologic Organ System|Integument of body|System, Integumentary|Systems, Integumentary|Structure of integumentary system|Integument|Integumentary Systems|Body System, Dermatologic

Integumentary system

C0019010

The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.

Hemodynamics|Hemodynamic|hemodynamics

Hemodynamics

C0037658

Area of the parietal lobe concerned with receiving sensations such as movement, pain, pressure, position, temperature, touch, and vibration. It lies posterior to the central sulcus.

somesthetic sensory cortex|primary sensory cortex|Cortex, Somatosensory|Somatosensory cortex|Somatosensory Cortex|somatosensory cortex

Somatosensory Cortex

C0036658

The process in which specialized SENSORY RECEPTOR CELLS transduce peripheral stimuli (physical or chemical) into NERVE IMPULSES which are then transmitted to the various sensory centers in the CENTRAL NERVOUS SYSTEM.

Sensory perception, function|Sensation|sensory system function|Feeling - sensation|sense|functions sensory|Sensations|Esthesia|Organoleptic|Sensory function|Sensory perception, NOS|sensations|Sensation, NOS|Function, Sensory|sensory perception|Aesthesia|Sensory Functions|Observation of sensation|sensation|Sensory Function|perception by sense|Sensory perception, function (observable entity)|aesthesia|the senses|sensory function|Sensory perception|senses|Functions, Sensory|Sensory function (observable entity)|esthesia

Esthesia

C0423551

Sensory symptoms (finding)|sensory symptoms

Sensory symptoms

C0144576

A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.

[2aR-[2a alpha,4beta,4a beta,6beta,9alpha(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-(benzoylamino)-alpha-hydroxybenzene-propanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1a,33,4,-41,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-41,8,-12,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester|5beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one, 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|Product containing paclitaxel (medicinal product)|[2aR-[2a Alpha,4beta,4a beta,6beta,9alpha(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-(benzoylamino)-alpha-hydroxybenzene-propanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1a,33,4,-41,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-41,8,-12,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester|Paclitaxel-containing product|Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,1-2alpha,12aalpha,12balpha))-|TAX|5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|5Beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one, 4,10-Diacetate 2-Benzoate 13-Ester with (2R,3S)-N-Benzoyl-3-phenylisoserine|PACLITAXEL|(2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha R*,betaS*),11alpha,12alpha,12balpha))-beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Paclitaxel (substance)|Paclitaxel|PACLitaxel|Paclitaxel Preparation|paclitaxel

paclitaxel

C0006549

The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated. [NIF_Subcellular:nlx_subcell_20090210]

c fibers|c fiber|C-fiber|C Fiber|C-fibre|C fiber

C Fibers

C0682682

myelinated axon

C0026046

Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.

Micro-tubule|Microtubulus|microtubules|Microtubule|microtubuli|Micro Tubule|Microtubules|microtubule|microtubulus

Microtubules

C0026237

Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)

Mitochondrial|Mitochondrion (cell structure)|Mitochondrion|Mitochondrion, NOS|Mitochondrial structure (cell structure)|mitochondrion|mitochondria|Mitochondrial structure|Mitochondria|mitochondrial

Mitochondria

C0007894

Infections with true tapeworms of the helminth subclass CESTODA.

Cestode infection, NOS|cestode infection|Tapeworm infection NOS|Cestode Infections|tapeworm infections|Infection, Cestode|Infection, Tapeworm|Cestode infection (disorder)|cestode infections|tapeworm infection|cestode infestation|Cestode infestation|Infections, Tapeworm|Tapeworm infection|cestodes|Infections, Cestode|Tapeworm Infections|cestodiasis|Cestodiasis|Disease due to Cestoda|Tapeworm Infection|CESTODIASIS|Cestode infection|Cestodosis|Cestode Infection|tapeworm|Tapeworm NOS|Cestode infection, unspecified|DISEASES DUE TO CESTODA|Tapeworm infection, NOS|TAPEWORM INFECTION

Cestode Infections

C0034237

Broad spectrum antinematodal anthelmintic used also in veterinary medicine.

pamoate pyrantel|Pamoate, Pyrantel|Pyrantel Pamoate|PYRANTEL PAMOATE|Pyrantel pamoate|Pyrantel pamoate (substance)|Pyrantel Embonate|Embonate, Pyrantel|pyrantel embonate|pyrantel pamoate|2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy), compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)pyrimidine (1:1)

pyrantel pamoate

C0004573

A species of protozoa that is a cause of bovine babesiosis. Ticks of the genera Boophilus, Rhipicephalus, and IXODES are the chief vectors.

bovis, Babesia|Babesia bovi|Babesia bovis (organism)|Babesia bovis

Babesia bovis

C1166950

The plastid organelle found in apicomplexans. [ISBN:0521664470]

Plastids, Apicomplexan|Apicomplexan Plastids|apicoplast|Plastid, Apicomplexan|Apicomplexan Plastid|Apicoplast

Apicoplasts

C0001473

A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.

atpase|ATP Hydrolase|Adenosine triphosphatase|Adenosine Triphosphatases|Adenylpyrophosphatase|adenosinetriphosphatase|adenosine triphosphatases|ATP monophosphatase|Adenosine triphosphatase (ATP'ase)|Adenosinetriphosphatase (substance)|ATPase|ATPases|Adenosine Triphosphatase|adenosine triphosphatase|Adenosinetriphosphatase|ATP phosphohydrolase

Adenosine Triphosphatases

C1166795

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. [ISBN:0198547684]

spindle|Spindle|spindles

Spindle

C0344315

An emotional state characterized by feelings of sadness, emptiness, and/or tearfulness.

depression|Morose mood|Depressed Mood|melancholic|miserable|Morosity|Depressed mood (finding)|Depressed|Depressed mood|melancholy|depressed mood|depressed|Decreased Mood|depression moods|Low Mood|feeling down|depressing

Depressed mood

C1278838

Entire lumbar spinal cord|Entire lumbar spinal cord (body structure)

Entire lumbar spinal cord

C1185742

A bundle of nerve fibers crossing from one side to the other side of the brain or spinal cord.

Commissura|Commissure|commissure|commissures

Commissure

C0007450

The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)

Felis silvestris catus|Feline species|cats|Domestic cat|Cats|Cat, Domestic|Domestic Cat|Mammals, Cats|FELIS CATUS|domesticus felis|Felis domestica|CAT|Felis domesticus|cat|Feline, NOS|Cats, Domestic|Domestic Cats|FELINE SPECIES|felines|Cat|Felis sylvestris catus|Felis catus (organism)|Feline Species|Felis catus|domestic cat

Felis catus

C0004461

Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.

Axon structure|axone|neuraxons|Axon|Axon structure (cell structure)|neuraxon|axon|Axons|axons

Axon

C0058990

A component of eukaryotic initiation factor-4F that is involved in multiple protein interactions at the site of translation initiation. Thus it may serve a role in bringing together various initiation factors at the site of translation initiation.

Eukaryotic-Translation Initiation Factor 4G|eIF-4G|EIF-4G|Eukaryotic Peptide Initiation Factor-4G|EIF 4G|eIF-4-gamma|Eukaryotic Translation Initiation Factor 4 gamma|Peptide Initiation Factor EIF 4G|eIF4G|Eukaryotic Peptide Initiation Factor 4G|EIF4G|Eukaryotic Initiation Factor-4G|Eukaryotic Initiation Factor 4G|eIF4G Family|Eukaryotic Translation Initiation Factor 4 Gamma|Peptide Initiation Factor EIF-4G|Eukaryotic Translation Initiation Factor 4G|Eukaryotic Translation Initiation Factor 4 Gamma Family

Eukaryotic Initiation Factor-4G

C0058990

A component of eukaryotic initiation factor-4F that is involved in multiple protein interactions at the site of translation initiation. Thus it may serve a role in bringing together various initiation factors at the site of translation initiation.

Eukaryotic-Translation Initiation Factor 4G|eIF-4G|EIF-4G|Eukaryotic Peptide Initiation Factor-4G|EIF 4G|eIF-4-gamma|Eukaryotic Translation Initiation Factor 4 gamma|Peptide Initiation Factor EIF 4G|eIF4G|Eukaryotic Peptide Initiation Factor 4G|EIF4G|Eukaryotic Initiation Factor-4G|Eukaryotic Initiation Factor 4G|eIF4G Family|Eukaryotic Translation Initiation Factor 4 Gamma|Peptide Initiation Factor EIF-4G|Eukaryotic Translation Initiation Factor 4G|Eukaryotic Translation Initiation Factor 4 Gamma Family

Eukaryotic Initiation Factor-4G

C0031715

The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.

Phosphorylation|phosphorylation|Phosphorylation, function (observable entity)|Phosphorylations|Phosphorylation Process|Phosphorylation, function

Phosphorylation

C0597304

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah]

Degradations, Protein|Proteolyses|Protein Degradation|Proteolytic|peptidolysis|Proteolysis|Degradation, Protein|proteolysis|Protein Degradations|Protein Cleavage

Proteolysis

C0018790

Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.

HEART ARREST|arrest|arrested|STANDSTILL CARDIAC|Heart stops beating|asystole|CARDIAC ARREST|Heart Arrest|Cardiac arrest (disorder)|cardiac asystole|Asystole|CARDIAC ASYSTOLE|cardiac arrest|VENTRICULAR ASYSTOLIA|Asystoles|Cardiac arrest|ventricular asystole|heart arrest|Arrest, Heart|ASYSTOLE|Arrest, Cardiac|Asystole (disorder)|asystolia|Cardiac standstill|Cardiac Arrest|arrest [as an cardiac arrest]|ARREST CARDIAC|SCA

Cardiac Arrest

C0058990

A component of eukaryotic initiation factor-4F that is involved in multiple protein interactions at the site of translation initiation. Thus it may serve a role in bringing together various initiation factors at the site of translation initiation.

Eukaryotic-Translation Initiation Factor 4G|eIF-4G|EIF-4G|Eukaryotic Peptide Initiation Factor-4G|EIF 4G|eIF-4-gamma|Eukaryotic Translation Initiation Factor 4 gamma|Peptide Initiation Factor EIF 4G|eIF4G|Eukaryotic Peptide Initiation Factor 4G|EIF4G|Eukaryotic Initiation Factor-4G|Eukaryotic Initiation Factor 4G|eIF4G Family|Eukaryotic Translation Initiation Factor 4 Gamma|Peptide Initiation Factor EIF-4G|Eukaryotic Translation Initiation Factor 4G|Eukaryotic Translation Initiation Factor 4 Gamma Family

Eukaryotic Initiation Factor-4G

C0021792

Most generally any NEURONS which are not motor or sensory. Interneurons may also refer to neurons whose AXONS remain within a particular brain region in contrast to projection neurons, which have axons projecting to other brain regions.

Interneurons|internuncial neuron|Interneuron|Neuron, Intercalated|connector neuron|Intercalated Neurons|Internuncial Neuron|Neurons, Intercalated|intercalated neuron|interneurons|Internuncial Cell|Connector Neuron|intercalary neuron|internuncial cell|interneuron|Intercalated Neuron

Interneurons

C0486805

fragments

Fragments

C0014653

see:http://www.nlm.nih.gov/mesh/MBrowser.html

Equilibrium, function (observable entity)|equilibrium|Balancing|Equilibrium|Balance|Balance (observable entity)|balance|Equilibrium, function|Equilibrium, NOS|balancing

Equilibrium

C0394006

Dysequilibrium syndrome|DES - Dysequilibrium syndrome|dysequilibrium syndrome|Dysequilibrium syndrome (disorder)|Dysequilibrium|Disequilibrium|disequilibrium syndrome

Dysequilibrium syndrome

C0035339

A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization.

Retinoid|Product containing retinoid (product)|Retinoids|Retinoic Acid and Derivatives|Retinoic Acid Agent|retinoids|Retinoic Acids|Retinoid-containing product|Retinoid (substance)|retinoid

Retinoids

C0026649

The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.

body movement|Movement (observable entity)|Movement|body movements|Movements|Quality of movement

Movement

C0031843

Used with organs, tissues, and cells of unicellular and multicellular organisms for normal function. It is used also with biochemical substances, endogenously produced, for their physiologic role.

function|physiology

physiological aspects

C0002658

A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.

Amfetamine (substance)|α-methylbenzeneethaneamine|Desoxynorephedrine|speed|Amfetamine|α-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|rac-amphetamine|1-phenylpropan-2-amine|Amfetamine-containing product|d,1-alpha- Methylphenethylamine|AMPHETAMINE|β-aminopropylbenzene|Amphetamine, NOS|Benzeneethanamine, alpha-methyl-, (+-)-|dl-Amphetamine|Amphetamine-containing product|Desoxynorephedrin|Amfetaminum|1-phenyl-2-aminopropane|dl-alpha-methylphenethylamine|amfetamine|Product containing amfetamine (medicinal product)|Phenamine|Amfetamina|alpha-Methylbenzeneethaneamine|amphetamine|Phenopromin|beta-Aminopropylbenzene|Amphetamine|Phenylaminopropane

amphetamine

C0005034

Compounds with BENZENE fused to AZEPINES.

Product containing benzazepine (product)|Benzazepine (substance)|Benzazepine|benzazepines|Benzazepine-containing product|benzazepine

Benzazepines

C0681814

A coordinated set of actions and observations designed to generate data, with the ultimate goal of discovery or hypothesis testing.

experimental study|experimental studies|experimenting|research study|Experiments|experiments|experimental research|experiment|research studies|Experiment

research study

C1522240

A sequence of events which produces some outcome.

Processed|Process (observable entity)|Process

Process

C0151740

Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.

increase intracranial pressure|hypertension intracranial|HYPERTENSION INTRACRANIAL|Intracranial Pressure, Elevated|PRESSURE CEREBROSPINAL FLUID INCREASED|Raised intracranial pressure (finding)|Increased intracranial pressure|Cerebrospinal fluid pressure, increased|ICP, Elevated (Intracranial Pressure)|Pressure Increase, Intracranial|Intracranial pressure elevation|intracranial pressure increase|Hypertension, Intracranial|RIP - Raised intracranial pressure|raised intracranial pressure|increased intracranial pressure|Pressure, Elevated Intracranial|Increased cerebrospinal fluid pressure|intracranial hypertension|ICP (Intracranial Pressure) Elevation|Elevated ICP (Intracranial Pressure)|Intracranial Pressure Increase|ICP (Intracranial Pressure) Increase|PRESSURE INTRACRANIAL INCREASED|Rise in pressure inside skull|INTRACRANIAL PRESSURE, INCREASED|Raised intracranial pressure|Intracranial hypertension|INTRACRANIAL PRESSURE INCREASED|intracranial pressure raised|INTRACRANIAL HYPERTENSION|Elevated Intracranial Pressure|hypertensions intracranial|Intracranial Hypertension|intracranial increased pressure

Intracranial Hypertension

C0020255

Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA.

Hydrencephalus|hydrocephaly|Water on the brain|hydrencephalus|Hydrocephalus|Nonsyndromal hydrocephalus|Hydrocephaly|hydrencephaly|hydrocephalus|Hydrocephalus (disorder)|HYDROCEPHALUS|Too much cerebrospinal fluid in the brain|Hydrencephaly

Hydrocephalus

C1442858

Shunt|Surgical fistula (morphologic abnormality)|Surgical fistula

Surgical fistula

C0021153

An incision that relieves abnormal pressure on a structure

Decompressive incision|Decompression|Incision, decompressive|Decompressive incision (procedure)|decompression

Decompressive incision

C0149784

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:mah]

stress reactions|stress response|Reactions to Crisis|response stress|reaction stress|responses stress|stress reaction|STRESS REACTION|response to stress|reactions stress|biological adaptation to stress

biological adaptation to stress

C0180463

A container designed to give out the contents in convenient or/and prescribed amounts.

Dispenser|dispenser|dispensers|Dispenser (physical object)|Dose dispenser|Dispensers

Dispenser

C0035372

An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)

retts syndrome|Autism, Dementia, Ataxia, and Loss of Purposeful Hand Use|rett disorder|disorder retts|Rett's disorder|AUTISM, DEMENTIA, ATAXIA, AND LOSS OF PURPOSEFUL HAND USE|rett's syndrome|rett syndrome|Retts Syndrome|RTS|Retts syndrome|Autism-Dementia-Ataxia-Loss of Purposeful Hand Use Syndrome|Rett Disorder|Syndrome, Rett|Rett disorder|Rett's Disorder|Cerebroatrophic Hyperammonemia|Syndrome, Rett's|Cerebroatrophic hyperammonemia|Autism Dementia Ataxia Loss of Purposeful Hand Use Syndrome|Rett's disorder (disorder)|Cerebroatrophic Hyperammonemias|cerebroatrophic hyperammonemia|Hyperammonemia, Cerebroatrophic|RETT SYNDROME|Rett syndrome|rett's disorder|Cerebroatrophic hyperammonaemia|Hyperammonemias, Cerebroatrophic|RTS - Rett syndrome|Rett's Syndrome|syndrome rett|RTT|Rett Syndrome

Rett Syndrome

C0012940

Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.

Binding Protein, DNA|DNA-binding proteins|DNA Binding Protein|DNA binding protein|DNA Binding Proteins

DNA-Binding Proteins

C1414204

This gene is involved in both protein phosphorylation and signaling.

DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1A|DYRK1A|DYRK1A Gene|MNBH|DYRK|MNB|DYRK1|DYRK1A gene|DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE|dual specificity tyrosine phosphorylation regulated kinase 1A|MINIBRAIN, DROSOPHILA, HOMOLOG OF|DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1|MNB PROTEIN KINASE, SERINE/THREONINE-SPECIFIC

DYRK1A gene

C1414204

This gene is involved in both protein phosphorylation and signaling.

DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1A|DYRK1A|DYRK1A Gene|MNBH|DYRK|MNB|DYRK1|DYRK1A gene|DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE|dual specificity tyrosine phosphorylation regulated kinase 1A|MINIBRAIN, DROSOPHILA, HOMOLOG OF|DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1|MNB PROTEIN KINASE, SERINE/THREONINE-SPECIFIC

DYRK1A gene

C1148748

Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide. [GOC:jl, PMID:11746232]

methyl-CpG binding

C0684063

Organism or cells with a nucleus separated from the cytoplasm by a two membrance nuclear envelope and compartmentalization of function into distinct cytoplasmic organelles.

Eukaryotida|Eukaryotae|eukaryote organism|Domain Eukarya|eucariote organisms|eukarya|Superkingdom Eukaryota|eucaryotae|Eukaryotes|eukaryotes|Eucaryotae|eukaryota|Eukaryote|Eukaryotas|Eukarya|Eucarya|Domain Eukarya (organism)|Eukaryota

Eukaryota