ENTITY
stringlengths
8
8
DEFINITION
stringlengths
3
8.47k
ALIASES
stringlengths
2
13.6k
NAME
stringlengths
2
1.98k
C0063082
null
null
hydroethidine
C0241950
null
Bowel infarction|infarcts intestinal|intestinal infarction|Intestinal infarction|INTESTINAL INFARCTION
bowel infarction
C0241950
null
Bowel infarction|infarcts intestinal|intestinal infarction|Intestinal infarction|INTESTINAL INFARCTION
bowel infarction
C1182610
null
Corneal epithelial cell|Epithelial cell of cornea
Corneal epithelial cell
C0040676
Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor). The classification is based on the scheme "donor:acceptor group transferase". (Enzyme Nomenclature, 1992) EC 2.
Substance with transferase mechanism of action|transferase|EC 2|transferases|TRANSFERASES|Substance with transferase mechanism of action (substance)|Transferase, NOS|Transferase|Transferases
Transferase
C0033063
Region of hypothalamus between the ANTERIOR COMMISSURE and OPTIC CHIASM.
Nuclei, Preoptic|Preoptic area structure|Area preoptica|Preoptic region of hypothalamus|Area Preoptica|Preoptic Areas|Preoptic nuclei|Preoptic Nucleus|preoptic nucleus|preoptic region|preoptic area|Area, Preoptic|Preoptic area structure (body structure)|Nucleus, Preoptic|Preoptic area|Areas, Preoptic|Preopticas, Area|Area Preopticas|Preoptic Nuclei|Preoptic Area|Preoptica, Area|Area praeoptica
Preoptic Areas
C1257880
A collective term for a group of around nine geometric and positional isomers of LINOLEIC ACID in which the trans/cis double bonds are conjugated, where double bonds alternate with single bonds.
Linoleic Acids, Conjugated|CONJUGATED LINOLEIC ACID|conjugate linoleic acid|conjugated linoleic acids|acid conjugated linoleic|Acids, Conjugated Linoleic|Conjugated Linoleic Acids|Conjugated Linoleic Acid (CLA)
linoleic acids, conjugated
C0242606
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
oxidative stress|Oxidative Stress|Stresses, Oxidative|Stress, Oxidative|Oxidative stress|Oxidative Stresses|stress oxidative
Oxidative Stress
C0032105
The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.
blood plasma|Plasma (substance)|PLASMA|Blood Plasmas|plasma|Plasma, Blood|Blood plasma|Plasmas|Plasma|Portion of plasma|Blood plasma (product)|Blood Plasma|Plasmas, Blood
Plasma
C0020473
Conditions with excess LIPIDS in the blood.
hyperlipemia|Hyperlipemia|Hyperlipidaemia|HYPERLIPEMIA|Hyperlipidemia, NOS|HYPERLIPAEMIA|Hyperlipemias|Hyperlipidaemia, NOS|excessive fat in the blood|HLD - Hyperlipidemia|hyperlipidaemias|Hyperlipidemias|Hyperlipidemia|hyperlipidemia|Elevated lipids in blood|Hyperlipidemia (disorder)|hyperlipidaemia|HYPERLIPIDEMIA|Hyperlipidemia NOS|Lipidaemia|Lipidemia|lipidemia|HLD - Hyperlipidaemia|hyperlipidemias|Disorder characterized by hyperlipidemia|lipidaemia
Hyperlipidemia
C0022203
The phenomenon whereby certain chemical compounds have structures that are different although the compounds possess the same elemental composition. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Isomerism|Isomerisms|isomer|isomers|isomerism|Isomer
Isomerism (chemical phenomenon)
C0253005
null
chitotriosidase
chitotriosidase
C0850624
null
cardiovascular factors risk|cardiovascular factor risk
cardiovascular risk factor
C0024432
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
Monocyte-Derived Macrophages|Clasmatocyte|Bone Marrow Derived Macrophages|Macrophage, Bone Marrow-Derived|macrophages|Macrophages|Macrophages, Monocyte Derived|Macrophages, Bone Marrow-Derived|Monocytes / Macrophages / APC|macrophage|Macrophage, Monocyte-Derived|Bone Marrow-Derived Macrophage|Bone Marrow-Derived Macrophages|Macrophages, Monocyte-Derived|Macrophage (cell)|Macrophage|Monocyte-Derived Macrophage|Monocyte Derived Macrophages
macrophage
C0024880
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
Marrow mast cell|Cells, Mast|mastocyte|Basophils, Tissue|Histaminocyte|Tissue Basophils|cell mast|Mast Cell|Mast cells|Mast cell|Mastocyte|cells mast|Basophil, Tissue|Mast cell (cell)|Basophilic histiocyte|Tissue basophil|Mast Cells|mastocytes|mast cell|Tissue Basophil|mast cells|tissue basophil|Cell, Mast
mast cell
C0440752
null
cells inflammatory|Inflammatory cell (cell)|inflammatory cells
Inflammatory cell
C0003842
The vessels carrying blood away from the heart.
Arterial vessel|Arteries|Arterial tree|Arterial tree (organ part)|Artery|arteri|Arterial subtree|Arterial|Arterial structure (body structure)|anatomy arteries|arteris|Artery, NOS|Arteries set|ARTERY|arterial structure|Set of arteries|artery|Arteriae|Arterial structure|Arterial tree organ part|arteries anatomy|Arteria|arteries
Arteries
C0023820
Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
Lipoproteins|Lipoprotein-containing product|Circulating Lipoproteins|lipoproteins|Lipoprotein|Lipoprotein, NOS|Lipoproteins, Circulating|Lipoprotein (substance)|lipoprotein|Product containing lipoprotein (product)
Lipoproteins
C0023820
Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
Lipoproteins|Lipoprotein-containing product|Circulating Lipoproteins|lipoproteins|Lipoprotein|Lipoprotein, NOS|Lipoproteins, Circulating|Lipoprotein (substance)|lipoprotein|Product containing lipoprotein (product)
Lipoproteins
C0004358
Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.
Autoantibodies|antibodies autoimmune|autoantibodies|Autoantibody (substance)|self reactive antibody|autoimmune antibody|Autoantibody|autoantibody|Abs - Autoantibodies
Autoantibodies
C0030705
Individuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures.
patient|Patients|PATIENT|LAY USER/PATIENT|Patient (person)|patients|Patient|PT
Patients
C0003338
Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.
Protozoal antigen|Antigen of Protozoa (substance)|protozoal antigen|Protozoan Antigens|Antigen of Protozoa|Protozoa Ag|Protozoa antigen
Antigens, Protozoan
C0003338
Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.
Protozoal antigen|Antigen of Protozoa (substance)|protozoal antigen|Protozoan Antigens|Antigen of Protozoa|Protozoa Ag|Protozoa antigen
Antigens, Protozoan
C0009566
In medicine, a medical problem that occurs during a disease, or after a procedure or treatment. The complication may be caused by the disease, procedure, or treatment or may be unrelated to them.
Complication, NOS|complications|complication|Complication|Complications|complications medical|Other complication|Medical Complication|Complication (disorder)|medical complication
Complication
C0010054
Thickening and loss of elasticity of the CORONARY ARTERIES, leading to progressive arterial insufficiency (CORONARY DISEASE).
coronary heart disease|ashd|myocardial ischemia|ARTERIOSCLEROTIC HEART DISEASE|CORONARY SCLEROSIS|ARTERIOSCLEROSIS CORONARY ARTERY|ASHD|coronary sclerosis|CORONARY ATHEROSCLEROSIS|CORONARY ARTERIOSCLEROSIS|Coronary Atherosclerosis|coronary arteriosclerosis|coronary atheroma|cardiac ischemia|Coronary arteriosclerosis|coronary artery disease|Coronary Atheroscleroses|Arteriosclerosis, Coronary|Atherosclerosis of coronary artery|coronary artery diseases|ATHEROSCLEROTIC CORONARY VASCULAR DISEASE|coronary artery atherosclerosis|Atherosclerosis, Coronary|myocardial ischaemia|Arteriosclerotic heart disease|Atheroscleroses, Coronary|Atherosclerosis of native coronary artery|Coronary sclerosis|Coronary Arteriosclerosis|Arterioscleroses, Coronary|Coronary atherosclerosis|coronary atherosclerosis|Coronary artery sclerosis|atherosclerotic heart disease|cardiac ischaemia|Plaque build-up in arteries supplying blood to heart|Coronary arteriosclerosis (disorder)|arteriosclerotic heart disease|ischaemic heart disease|ATHEROSCLEROTIC HEART DISEASE|Arteriosclerotic coronary artery disease|Atherosclerosis of coronary artery (disorder)|Coronary artery atherosclerosis|Coronary artery arteriosclerosis|Coronary Arterioscleroses|Atherosclerotic heart disease
Coronary Arteriosclerosis
C0205847
A person between young adult and elderly, approximately 40-60 years of age.
middle aged|Middle Aged|aged middle|middle ages|ages middle|Middle Ages|Middle Adult|Middle Age
Middle Aged
C0205042
A principal artery that originates in the aorta. It supplies blood to the muscular tissue of the heart.
Coronary artery, NOS|Artery, Coronary|coronary artery|CORONARY ARTERY|Coronary Arteries|Arteries, Coronary|Set of coronary arteries|coronary arteries|Coronary arteries|Coronary artery|Coronary artery structure (body structure)|Coronary arterial tree|CORONARY ARTERIES|Coronary arteries set|Coronary artery structure|ARTERY, CORONARY|Coronary Artery|Arteriae cornarae
Coronary artery
C0040395
Imaging methods that result in sharp images of objects located on a chosen plane and blurred images located above or below the plane.
Diagnostic tomography, NOS|tomograms|Tomographic imaging|Tomogram|Tomographic imaging - action (qualifier value)|Diagnostic tomographic examination, NOS|tomogram|Diagnostic laminographic examination, NOS|Diagnostic tomography (procedure)|Tomographic imaging procedure (procedure)|Tomography|Tomographic imaging, plain radiologic - action|Tomographic imaging procedure|tomography|Tomographic imaging - action|Diagnostic laminographic examination|Diagnostic tomography|Tomographic imaging, plain radiologic - action (qualifier value)|Diagnostic tomographic examination|tomographies|Tomographies
tomography
C0022877
Facilities equipped to carry out investigative procedures.
LABORATORY|Laboratory|Laboratories|laboratories|Laboratory (environment)|laboratory|Lab
Laboratory
C0201699
A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of PROTEINS; NUCLEIC ACIDS; and CARBOHYDRATES. (Segen, Dictionary of Modern Medicine, 1992)
Capillary Zone Electrophoreses|Electrophoreses, Capillary|Capillary Electrophoresis|Capillary Zone Electrophoresis|Electrophoreses, Capillary Zone|Zone Electrophoreses, Capillary|Zone Electrophoresis, Capillary|Electrophoresis, Capillary Zone|Fractionation, Capillary Electrophoresis|Capillary electrophoresis|CAPILLARY ELECTROPHORESIS|Capillary electrophoresis (procedure)|Capillary Electrophoreses|capillary electrophoresis|Capillary electrophoresis, NOS
Electrophoresis, Capillary
C0075615
The active metabolite of sulindac, a sulfinylindene derivative with anti-inflammatory, analgesic and antipyretic properties. Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) which inhibits cyclooxygenase (COX-1 and-2)-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins. This agent may possess chemopreventive activity against colorectal tumors through a mechanism that involves the induction of apoptosis. The sulfide metabolite is excreted in the bile and reabsorbed from the intestine, thereby helping to maintain constant blood levels and reduce gastrointestinal side effects. (NCI04)
Sulindac Sulfide|(1Z)-5-Fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic Acid|Sulindac sulfide|1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-(4-(methylthio)phenyl)methylene-, (Z)-|Sulindac sulfide (substance)
sulindac sulfide
C0075616
An inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac. After oral administration, sulindac undergoes extensive biotransformation including irreversible oxidation to sulindac sulfone. Approximately, one half of an administered dose of sulindac is eliminated through the urine, mostly as the conjugated sulfone metabolite. (NCI04)
Sulindac Sulfone|EXISULIND|Exisulind|5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid|Sulindac sulfone|exisulind|cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid|(Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid
sulindac sulfone
C0182324
An object designed to fill a hole tightly; anything that resembles such an object in appearance or origin.
Plug|plugs|plug|Plug (physical object)
Plug (physical object)
C0038792
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Product containing sulindac (medicinal product)|(Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid|sulindac|cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid|cis-5-fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid|(Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|SULIN|Sulindac-containing product|Sulindaco|Sulindacum|1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-|Sulindac|Sulindac (substance)|SULINDAC|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
sulindac
C0243114
null
purification
purification aspects
C0871615
null
word recognition
Word Recognition
C0439824
Expressed in spoken words.
Verbal (qualifier value)|Verbal|verbal
Verbal
C1504389
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
cell stem transplantation|Stem Cell Transplantation|Stem Cell Transplantations|Stem cells--Transplantation|Transplantations, Stem Cell|cells stem transplantations|Transplantation, Stem Cell|cells stem transplantation|stem cell transplantation|stem cell transplantations
Stem cell transplant
C0024312
Reduction in the number of lymphocytes.
Disorder characterized by lymphopenia|Lymphopenia|Lymphopenias|Lymphocytopenias|Lymphocytopenia|lymphocytopenia|lymphopenia|Absolute lymphocyte count decrease|LYMPHOPENIA|decreased lymphocyte|Low lymphocyte number|Lymphocytopenia, NOS|LYMPHOCYTOPENIA|Decreased blood lymphocyte number|decreased lymphocytes|Lymphocytopenia (disorder)
Lymphopenia
C1515126
Development of bone marrow-derived stem cells in the thymus through stages of positive selection under the influence of epithelial cells in the thymic cortex and negative selection under the influence of bone marrow-derived dendritic cells at the corticomedullary junction. Thymic T cell precursors (thymocytes) progress through phases expressing both CD4 and CD8 coreceptors to a single positive stage expressing only CD4 or CD8 in addition to the T cell receptor. They are then allowed to leave the thymus and enter the periphery via the lymphatics or venules of the circulatory system as mature T cells. (NCI/OSP)
T-Lymphocyte Development|T-Cell Development|T cell development|T-Cell Differentiation|T-Cell Ontogeny
T-Cell Development
C0175996
The organized colloidal complex of organic and inorganic substances (as proteins and water) that constitutes the living nucleus, cytoplasm, plastids, and mitochondria of the cell. It is composed mainly of nucleic acids, proteins, lipids, carbohydrates, and inorganic salts.
Protoplasms|protoplasm|intracellular|internal to cell|Protoplasm
Protoplasm
C0040732
Transference of a tissue or organ from either an alive or deceased donor, within an individual, between individuals of the same species, or between individuals of different species.
Transplant Procedure|Transplantation - action|Tx - Transplant|Transplantation (procedure)|transplanting|transplantation|transplantation procedure|transplant procedure|Transplant procedure|transplant|transplanted|transplantations|Transplantations|Transplantation - action (qualifier value)|Surgery, Transplantation|procedures transplant|Transplantation|Transplant|Transplant (qualifier value)|Transplantation Surgery|Transplantation, NOS|Grafting Procedure|procedures transplantation
Transplantation
C1272835
A packaged system consisting of the main component materials necessary to perform one or more designated diagnostic tests or procedures.
test kit|Test Kit|kits testing|kit testing|Test kit (physical object)|Test Kits|kits test
Test kit
C0443769
null
Volatile compound|volatile substances|Volatile agent|Volatile agent (substance)|agents volatile|volatiles|Volatile substance
volatile substances
C0027061
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
heart muscles|Cardiac muscle|CARDIAC MUSCLE TISSUE|Cardiac muscle tissue|Cardiac Muscles|cardiac muscle (tissue)|Cardiac muscle (tissue) (body structure)|Cardiac muscle (tissue)|myocardia|Heart Muscle|Muscles, Heart|Heart Muscles|Myocardia|heart muscle|Muscle of heart|Muscle, Heart|Myocardium, NOS|Cardiac Muscle|Muscle, Cardiac|Myocardial tissue|Myocardial Tissue|cardiac muscles|Muscles, Cardiac|Heart muscle|Myocardium structure|Textus muscularis cardiacus striatus|cardiac muscle tissue|Myocardium|cardiac muscle|myocardium|Myocardial|Myocardium structure (body structure)
Myocardium
C0136157
formed by the diffusion limited reaction of superoxide with nitric oxide; may be a major mechanism of oxidative damage in the heart.
Peroxonitrites|Peroxynitrite|Peroxonitrite|Peroxynitrites|peroxynitrite
Peroxynitrite
C0000970
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
ACMP|4-Hydroxyacetanilide|ACETAMINOPHEN|4'-hydroxyacetanilide|Acetamide, N-(4-hydroxyphenyl)-|Hydroxyacetanilide|Product containing paracetamol (medicinal product)|Acetaminofén|4-acetamidophenol|Paracetamol (substance)|Paracetamol|p-Hydroxyacetanilide|p-Acetylaminophenol|Acetominophen|paracetamol|Paracetamol-containing product|N-acetyl-p-aminophenol|Acenol|p-hydroxyacetanilide|Paracétamol|Acetamidophenol|p-Acetamidophenol|4-(Acetylamino)phenol|Acetaminophen|Acetaminophen-containing product|N-(4-Hydroxyphenyl)acetamide|p-acetaminophenol|acetaminophen|p-hydroxy-acetanilid|N-(4-hydroxyphenyl)acetamide|N-Acetyl-p-aminophenol|Paracetamolum|APAP|p-acetamidophenol|N-(4-Hydroxyphenyl)acetanilide
acetaminophen
C1522565
Of or relating to a ventricle (of the heart or brain).
Ventricular
Ventricular
C0596981
Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.
cells muscle|Myocyte|Mature Muscle Cell|Muscle cells|Myocytes|Muscle Cell, Mature|myocytes|Muscle cell|Muscle Cells, Mature|Mature Muscle Cells|cell muscle|muscle cell|muscle cells|myocyte|Muscle Cell|Muscle Cells
Muscle Cells
C0172537
A secreted endopeptidase homologous with INTERSTITIAL COLLAGENASE, but which possesses an additional fibronectin-like domain.
Type IV collagenase|TBE-1|Metalloproteinase 2, Matrix|Metalloproteinase, MMP-2|72kDa Gelatinase|72-kDa Type IV Collagenase|MMP2 Metalloproteinase|Gelatinase A|EC 3.4.24.24|MMP2|72 kDa Type IV Collagenase|MMP 2 Metalloproteinase|MMP-2|Matrix Metalloproteinase-2|72-kDa Gelatinase|72 kDa Gelatinase|gelatinase-A (MMP-2)|mmp-2|Matrix metalloproteinase 2|MMP-2 Metalloproteinase|Matrix Metalloprotease 2|Matrix Metalloproteinase 2|Gelatinase, 72-kDa|Matrix Metalloprotease-2|type iv collagenase|Metalloproteinase, MMP2|Gelatinase A (substance)|72kDa Type IV Collagenase
Matrix Metalloproteinase 2
C0003402
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
antioxidants|Antioxidant|Anti Oxidants|Anti-Oxidants|Antioxidants|antioxidant
Antioxidants
C0949707
Photosensory rhodopsins found in microorganisms such as HALOBACTERIA. They convert light signals into biochemical information that regulates certain cellular functions such as flagellar motor activity.
Rhodopsins, Sensory
Sensory Rhodopsins
C0033727
Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.
Hydrogen ion|Hydrogen Ion|hydrogen ions|H+ element|H^+^|Proton|H+|proton|Hydrogen Ions|Ions, Hydrogen|Proton (substance)|Protons|hydrogen ion|protons|H<sup>+</sup>|Ion, Hydrogen
Protons
C0968156
A member of the cofilin family of proteins that is expressed in MUSCLE CELLS. It has ACTIN depolymerization activity that is dependent on HYDROGEN-ION CONCENTRATION.
Muscle Cofilin|Cofilin, Muscle|CFL2 Protein|M-Cofilin|Cofilin-2|Cofilin 2
Cofilin 2
C1180307
A fibrillar actin polymer.
F-Actin|F Actin|Fibrillar actin|Filamentous Actin|Polymerized actin|F-actin
F-Actin
C0050633
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
Cofilin Proteins|Depolymerizing Proteins, Actin|ADF Proteins (Actin Depolymerizing Factors)|Actin Depolymerizing Proteins|Cofilins|Depolymerizing Factors, Actin
Actin Depolymerizing Factors
C0920283
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
DNA Unwinding Proteins|DNA Helicases|Helicase|helicases|EC 3.6.4.12|DNA helicases|DNA unwinding enzyme|helicase|Helicases|DNA Helicase|Helicases, DNA|Unwinding Proteins, DNA
DNA Helicases
C1517336
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)
Guanine Quadruplexes|G-Quartet Structures|G Quadruplexes|G-Quadruplexes DNA|G-Tetrads|Guanine-Quadruplexes|G-Quartets|G-Quadruplex|G4-DNA|G-Quadruplexes
G-Quadruplexes
C0680022
One of the persons who compose a social group, especially an individual who has joined and participates in a group organization.
member|Member|members|Member of (attribute)|Member of
member
C0015219
The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.
organic evolution|evolution|biological evolution|Evolution, Biological|Evolution
Biological Evolution
C0664843
null
null
1,3-dimethylisoguanine
C0664843
null
null
1,3-dimethylisoguanine
C1510779
null
Malignant Glandular Cell
Adenocarcinoma Cell
C0949466
<p>Molecular, Western Blot</p>
western blots|Western Immunoblots|western blot analysis|western blot assay|Blots, Western|blot testing western|Western blot analysis|western blot test|Western Blots|blot test western|western blot|western immunoblot|Western Immunoblot|blot western|assay blot western|Western blot assay|Immunoblots, Western|Western Blot|Western blot assay (procedure)|Immunoblot, Western|Blot, Western
Western Blot
C0027540
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Necroses|Cellular necrosis|Necrosis (morphologic abnormality)|cellular necrosis|Necrotic Process|NECROSIS|Necrosis, NOS|Necrosis|necrosis|NECROSES|Cellular necrosis, NOS|tissue death|death tissue|Tissue devitalization|Necrotic|necrotic cell death|necrotic|Tissue devitalisation
Necrosis
C1122629
A substance that has been studied in the treatment of several types of cancer. ZD6126 destroys blood vessels in tumors and may prevent the growth of new blood vessels that tumors need to grow. It is a type of vascular targeting agent and a type of antiangiogenesis agent.
ZD6126|Vascular Disrupting Agent ZD6126|ZD 6126|ZD-6126|zd6126
ZD-6126
C0024398
A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes.
Macaca|Macaca, NOS|macaca|Genus Macaca (organism)|Macacas|Macaques|macaque|macaques|Macaque|Macaque, NOS|Macacus|Genus Macaca
Macaca
C1282914
Extending on all sides of simultaneously; encircling.
circumscribed|Circumscribed|surrounding|surrounds|Circumscribed (qualifier value)|Surrounding (qualifier value)|Surrounding|Surround|surrounded|surround|Peri|surroundings|Surrounded
Surrounding (qualifier value)
C0206745
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
knockout mouse|Mice, Knock out|knock out mice|knockout mice|Knockout Mouse|Knock-Out Mouse|Knock-out Mice|Mouse, Knockout|Null Mouse|Knockout Mice|Mice, Knock-out
Mice, Knockout
C1001041
null
Alangium|Alangiums
Alangium
C0010614
An order of fish with 26 families and over 3,000 species. This order includes the families CYPRINIDAE (minnows and CARPS), Cobitidae (loaches), and Catostomidae (suckers).
ORDER CYPRINIFORMES|Cypriniformes|Order Cypriniformes|Order Cypriniformes (organism)
Cypriniformes
C0010614
An order of fish with 26 families and over 3,000 species. This order includes the families CYPRINIDAE (minnows and CARPS), Cobitidae (loaches), and Catostomidae (suckers).
ORDER CYPRINIFORMES|Cypriniformes|Order Cypriniformes|Order Cypriniformes (organism)
Cypriniformes
C0010614
An order of fish with 26 families and over 3,000 species. This order includes the families CYPRINIDAE (minnows and CARPS), Cobitidae (loaches), and Catostomidae (suckers).
ORDER CYPRINIFORMES|Cypriniformes|Order Cypriniformes|Order Cypriniformes (organism)
Cypriniformes
C0017428
The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.
Genome, NOS|Genomic|genome|genomes|Genomes|Genome (substance)|Genome
Genome
C0079941
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
Region, Protein Coding|open reading frame|Regions, Protein Coding|orf|Reading Frame, Open|Frame, Open Reading|Protein Coding Sequence|Frames, Open Reading|ORF|open reading frame (ORF)|Coding Region|Open Reading Frames|Coding Feature|Protein Coding Regions|Coding Region, Protein|Coding Regions, Protein|orfs|Protein Coding Region|protein coding sequences|Open Reading Frame|ORFs|Reading Frames, Open|Coding Sequence
Open Reading Frames
C0529535
null
PRKC apoptosis WT1 regulator protein|prostate apoptosis response-4 protein
PAWR protein
C0596901
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
membrane structure|membrane
Membrane
C0008555
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
vapor phase chromatography|Chromatography, Gas|Gas Chromatography|GC|Gas chromatography measurement (procedure)|gas chromatography|Gas Chromatographies|chromatography gas|Gas chromatography measurement, NOS|Gas chromatography (GC)|Gas chromatography|Chromatographies, Gas|Gas chromatography measurement
Gas Chromatography
C0008059
A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.
Children (0-21)|0-11 years old|CHILD|Children|children|Childhood age person (person)|Child Youth|Child|Child (person)|child|Child, NOS|Childhood age person
Child
C0032098
Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.
Kingdom Viridiplantae (organism)|Chlorophyta/Embryophyta group|green plants|plants|plant|Plant|Kingdom Viridiplantae|Chlorobionta|Plants|Kingdom Plantae|chlorophyte/embryophyte group|Viridiplantae|KINGDOM PLANTAE - PLANTS|Plantae|Kingdom Plantae (organism)|Plant, NOS|Plants, General
Plants
C0001128
Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant & Hackh's Chemical Dictionary, 5th ed)
Acid, NOS|Acid|acid substances|Acids|acidity|Acid (substance)|Acidic|acids|acid
Acids
C0002065
The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed)
alkane|Alkane (substance)|Alkane|alkanes|Alkanes
Alkanes
C0021156
Any of the eight frontal teeth (four maxillary and four mandibular) having a sharp incisal edge for cutting food and a single root, which occurs in man both as a deciduous and a permanent tooth. (Jablonski, Dictionary of Dentistry, 1992, p820)
incisor (dental)|Dens incisivus|incisor tooth|incisor|TOOTH, INCISOR|Incisor tooth|Structure of incisor tooth|INCISOR|incisors|Incisor|Structure of incisor tooth (body structure)|Incisors|Incisor tooth, NOS
Incisor
C1541679
null
Central incisor
Central incisor
C0340152
null
Acute pneumonitis caused by chemical fumes|Acute pneumonitis caused by chemical fumes (disorder)
Acute pneumonitis due to chemical fumes
C0340152
null
Acute pneumonitis caused by chemical fumes|Acute pneumonitis caused by chemical fumes (disorder)
Acute pneumonitis due to chemical fumes
C0340152
null
Acute pneumonitis caused by chemical fumes|Acute pneumonitis caused by chemical fumes (disorder)
Acute pneumonitis due to chemical fumes
C0340152
null
Acute pneumonitis caused by chemical fumes|Acute pneumonitis caused by chemical fumes (disorder)
Acute pneumonitis due to chemical fumes
C0340152
null
Acute pneumonitis caused by chemical fumes|Acute pneumonitis caused by chemical fumes (disorder)
Acute pneumonitis due to chemical fumes
C0040426
One of a set of bone-like structures in the mouth used for biting and chewing.
Tooth structure|tooth|Set of all teeth|Set of teeth|teeth|Dentes|structure tooth|set of teeth|Tooth|Tooth structure (body structure)|anatomy teeth|tooth structure|Dentition|teeth anatomy|TOOTH|Teeth set|Teeth|Tooth, NOS|sets teeth|structures tooth
Tooth structure
C0214745
null
p-octylphenol
4-octylphenol
C0678951
null
gene polymorphism|gene polymorphisms
gene polymorphism
C0699791
Cancer that forms in tissues lining the stomach.
Carcinoma of the Stomach|Gastric cancer, NOS|GASTRIC CARCINOMA|carcinomas gastric|Gastric Cancer|stomach carcinoma|Stomach Cancer|Gastric carcinoma|carcinoma of stomach|Cancer of the Stomach|Gastric (Stomach) Cancer|Carcinoma of Stomach|GASTRIC CANCER, CARCINOMA|Cancer of Stomach|CARCINOMA GASTRIC|Carcinoma of stomach (disorder)|carcinoma stomach|carcinomas stomach|carcinoma gastric|STOMACH CARCINOMA|Carcinoma of stomach|Gastric Carcinoma|Stomach Carcinoma|gastric cancer|gastric carcinoma|stomach cancer|CARCINOMA OF STOMACH|STOMACH, CARCINOMA|CARCINOMA STOMACH
Stomach Carcinoma
C0036614
Fluid from the prostate and other sex glands that helps transport sperm out of the man's body during orgasm. Seminal fluid contains sugar as an energy source for sperm.
Seminal fluid|seminal fluid|Semen|Portion of seminal fluid|semen|Seminal fliud|SEMINAL FLUID|Seminal fluid (substance)|Seminal Fluid
Seminal fluid
C0032615
A fatty acid containing more than one double bond (C=C). The essential fatty acids omega-3 and omega-6 are polyunsaturated fatty acids (PUFAs) that contain 2 or more cis double bonds. Dietary intake of some PUFAs may have beneficial effects on blood pressure, serum lipds, and inflammation. Some PUFAs, such as omega-3 PUFAs, may have antineoplastic or chemopreventive activities.
acids fatty polyunsaturated|Fatty Acid, Total Polyunsaturated|PUFA|PUFA (polyunsaturated fatty acid)|Polyunsaturated fatty acid (substance)|Polyunsaturated Fatty Acids|polyunsaturated fatty acids|polyunsaturated fatty acid|Polyunsaturated Fatty Acid|pufas|Acids, Polyunsaturated Fatty|Polyunsaturated fatty acid|pufa|Fatty Acids, Polyunsaturated|acid fatty polyunsaturated|PUFA - Polyunsaturated fatty acid
Polyunsaturated Fatty Acids
C0042874
A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
Vitamin E and vitamin E derivative (substance)|vitamin E|3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol|Vitamin E and vitamin E derivative-containing product|vitamin-E|tocopherol (vit E)|tocopherol|E vitamin|VITAMIN E PREPARATIONS|Vitamin E and vitamin E derivative|Product containing vitamin E and vitamin E derivative (product)|VIT E|Vitamin E|2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol|VITAMIN E|5,7,8-trimethyltocol|Vitamin E Compound|VIT-E|Vitamin E preparation|Vitamin E preparation, NOS|E Vitamin|5,7,8-Trimethyltocol|vit e
vitamin E
C0010405
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
Cryopreservation, NOS|cryopreservation|cold preservation|Storage, Cryopreservation|cold storage|Cryopreserved|Cryopreservation|Cryofixation|cryofixation|Cryopreservation (procedure)
Cryopreservation
C1518744
Tissue comprised of specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships in order to carry out the functions of production and ovulation of oocytes and the production and secretion of hormones.
Human Ovarian Tissue
Ovarian Tissue
C0042136
null
infections uterine|infection of uterus|UTERUS INFECTION|Infection of uterus|Uterine infection|infection uterus|uterine infection|uterus infection|UTERINE INFECTION|Infection of uterus (disorder)|infections uterus
Infection of uterus
C0021359
A reduced or absent capacity to reproduce.
Cannot achieve a pregnancy|INFERTILITY|Fertility issues|STERILITY|infertility|infertile|sterile|Not fertile|Infertile (finding)|sterility|Infertility, NOS|Sterile|Sterility|unable (to) get pregnant|Sterility, NOS|Infertility|unable to get pregnant|Sterility (finding)|Infertile|fertility issues|Difficulty conceiving|get pregnant unable
Infertility