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'Breathtaking': the consequences of chronic respiratory disorder. | ructured; tape-recorded interviews in order to cover in more detail some of the issues raised in the first quantitative stage of the study. Low correlations were found between lung function and disability (-0.38 p less than 0.001); accounting for only 14% of the variance; and high correlations between measures of dyspnoea and disability (-0.90 p less than 0.001). Major areas of disability and handicap included: household management; ambulation; sleep and rest; recreation and pastimes; and work. Financial pr | 2634677 | [
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'Breathtaking': the consequences of chronic respiratory disorder. | oblems and difficulties; housing problems and problems of social isolation were also frequently reported. The paper then attempts to explore the relationship between impairment; disability and handicap; drawing on both the quantitative and qualitative data collected in order to illustrate the variable nature of this relationship. The paper concludes by suggesting both the need for a more integrated approach to the care and rehabilitation of COAD patients and their families; and for a complementary social pe | 2634677 | [
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'Breathtaking': the consequences of chronic respiratory disorder. | rspective and approach to COAD and its treatment. | 2634677 | [
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Use of disablement resettlement officers by patients with musculoskeletal disorders. | to define the use of disablement resettlement officers (DRO) by patients with locomotor disorders.questionnaire for patients with locomotor disorders potentially handicapping them from obtaining work.outpatient clinics.52 patients; capable of work; aged 55 years or less; with a locomotor disorder; 19 had chronic arthritis and 18 back disorders. QUESTIONNAIRE: obtained details of diagnosis; work status; contact with DRO and results of referral.21 had seen the DRO and three of these were dissatisfied; 15 were | 2634676 | [
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Use of disablement resettlement officers by patients with musculoskeletal disorders. | referred to the DRO and only three were placed in employment; 16 did not want referral to the DRO; overall 60% were unemployed.Many patients are reluctant to see the DRO. Only a minority either attend or find work on referral. A modified system is needed to improve the employment prospects of patients with locomotor disorders. | 2634676 | [
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0.033451065,
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0.025395129,
0.043948587,
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0.036924124,
0.016999722,
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0.031126985,
0.0425907,
0.000097159624,
0.039248202,
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0.078862,
0.1123914,
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0.0078992555,
0.035331216,
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0.076041766,
0.06794666,
0.03995326,
0.0025688903,
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0.051887013,
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0.06794666,
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0.0350962,
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0.03384276,
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0.18007693,
0.054472223,
0.011829299,
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0.021687048,
0.008630427,
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0.06047827,
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0.004941931,
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0.018919045,
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0.055568982,
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0.08685265,
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0.012175299,
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0.0028936737,
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0.026609395,
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0.02673996,
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0.029064039
] |
The probability index. | nan | 2634696 | [
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0.02807132,
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0.0025753803,
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0.038098656,
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0.060477372,
0.05770941,
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0.034808435,
0.0049875556,
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0.017952587,
0.008982822,
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0.018905707,
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0.05551593,
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0.08685136,
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0.017769799,
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0.03394671,
0.047577623,
0.091760576,
0.06402872,
0.00862377,
0.07013913,
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0.06564772,
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0.0022146965,
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0.051442325,
0.004638296,
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0.05906728,
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0.045880288,
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0.05844057,
0.0043184133,
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0.007011302,
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0.012149006,
0.059485085,
0.0028658859,
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0.12116365,
0.0062507647,
0.17808968,
0.026504548,
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0.014819046,
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0.042668406,
0.069721326,
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0.02171284,
0.041023295,
0.052330162,
0.0095638335,
0.051834017,
0.071183644,
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0.022117589,
0.026635112,
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0.026739564,
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0.034860663,
0.09964666,
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0.024650535,
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0.019323513,
0.021987025,
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0.022457056,
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0.029063608
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0.027993396,
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0.03799477,
0.040945563,
0.078862,
0.0050822897,
0.046768818,
0.008016765,
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0.043191303,
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0.022927428,
0.020538066,
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0.014518963,
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0.04123281,
0.04073666,
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0.01630772,
0.007605482,
0.027784491,
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0.05217426,
0.0022538994,
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0.014923718,
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0.043112963,
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0.0017185778,
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0.00432827,
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0.022627125,
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0.24337542,
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Management of long standing post burn deformities of hand. | A study of 50 cases of long standing post burn deformities of hand in respect to their type of deformities; their operative correction; reconstruction and subsequent recovery had been carried out during the period from January 1979 to May 1986. Contractures were mainly due to shortage of skin and soft tissue; joint deformities developed secondary to that. Purpose of this study was to provide the patient with a good functioning hand. Of them 19 cases required skin grafting and 31 cases required different typ | 2634699 | [
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Management of long standing post burn deformities of hand. | es of skin flap like groin flap in 13; abdominal flap in 12 and transposition flap in 3;Z-plasty in 2 and buttock flap in one case for resurfacing the raw area which was created following release of contracture of skin and soft tissue. Six patients required capsulotomy and collateral ligament excision; 2 required excision arthroplasty and one patient required excision of lower end of ulna along with a flap cover. Deformities corrected at an earlier date showed better functional recovery than those which wer | 2634699 | [
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Management of long standing post burn deformities of hand. | e treated at a much later date. In this series; 3 children required secondary correction of their contracted flap due to their growing age; 3 adult patients developed contracture to the grafted skin for not using splint or having any physiotherapy; 2 patients had little extension deformities even after correction flap cover of hyperextension deformity; 2 patients with excision arthroplasty had weak grip and 3 patients were not followed up. Rest had good results. Extensive physiotherapy; proper splinting and | 2634699 | [
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Management of long standing post burn deformities of hand. | regular follow-up at least for 3 to 5 years after operation are the secrets of better functional recovery. | 2634699 | [
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Gall bladder disease: an analytical report of 250 cases. | Two hundred and fifty cases of biliary tract disease were studied as regards case history; physical and laboratory investigations; surgery and follow-up. It was found that females especially multipara were frequently affected; majority of cases were in 3rd to 5th decade of their life; rise in age showing decline in incidence. Majority of cases (82.4%) were vegetarians and had used vegetable fats (oriental diet). Most of the cases (98.8%) belonged to middle and poor class and were lean and thin. Pain in the | 2634700 | [
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Gall bladder disease: an analytical report of 250 cases. | right upper quadrant of the anterior abdominal wall had been the commonest symptom; in about half the cases it got aggravated by fatty meals. A mass was felt in the right hypochondrium in 29.6% and Murphy's sign was positive in 55.5% of cases. Radio-opaque calculi were present in 8% of cases; in another 10.8% the calculi were demonstrated by oral cholecystography; radiography could detect calculi in 47 (25.4%) cases and its overall diagnostic success rate has been low (56.8%). Ultrasonography proved more va | 2634700 | [
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Gall bladder disease: an analytical report of 250 cases. | luable tool for diagnosis; bile culture was positive in 8.8% of cases only for Esch coli; proteus; klebsiella; staphylococci or paracolon. Right subcostal incision gave the best results. Chronic cholecystitis with cholelithiasis (74%) was more common than acalculus cholecystitis (26%); incidence of carcinoma was 2.8%; and in 5 out of 7 cases malignancy was associated with cholelithiasis. Early diagnosis and cholecystectomy for gallstones can prevent malignancy. Surgery on the whole proved beneficial and it | 2634700 | [
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Gall bladder disease: an analytical report of 250 cases. | can be more rewarding if pre-operatively other causes of dyspepsia are either excluded or confirmed. Excluding cases of malignancy; the mortality has been quite low and thus acceptable. | 2634700 | [
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Usefulness of exploratory burr holes in the management of severe head injury. | The authors performed burr hole exploration for the diagnosis of intracranial haematomas in 110 consecutive patients with severe head injury. Burr hole revealed extra-axial mass lesions in 61 patients and 49 patients had negative exploration. Post-mortem study showed that only a very few clots were missed by routine burr holes. The study indicated that diagnostic burr hole exploration was a sensitive method for detecting extracerebral mass lesions in centres where CT scanning facilities were not available. | 2634701 | [
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Stricture urethra: aetiology and management. | Seventy-four male cases of stricture urethra; in all age groups up to 70 years were studied with regard to the aetiology of stricture; clinical presentation; investigations and treatment in Medical College Hospitals; Calcutta during June 1984 to May 1986. Depending on the site of affection and the aetiological consideration the treatment consisted of meatal dilatations; meatotomy; urethral dilatation and various methods of urethroplasty. Sixty-seven patients could be rendered asymptomatic. Traumatic strictu | 2634702 | [
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Stricture urethra: aetiology and management. | res specially of the anterior urethra was found to have a better prognosis. Preventive aspects like gentle urethral instrumentation; use of appropriately sized catheters made of non-reactive material and referral of patients with stricture urethra to urological centres were stressed upon. | 2634702 | [
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Comparative evaluation of the antihypertensive effect of timolol and propranolol in patients with essential hypertension. | Fifty patients with essential hypertension were studied for the antihypertensive effect of timolol and propranolol. In 16 out of 25 patients on timolol therapy (64%) blood pressure could be brought well under control (defined as diastolic blood pressure less than 90 mmHg) while with propranolol 13 out of 25 patients (52%) responded. Side-effects were negligible with timolol as compared to propranolol therapy. This study revealed that timolol is an effective and safe drug in essential hypertension; and is to | 2634703 | [
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Comparative evaluation of the antihypertensive effect of timolol and propranolol in patients with essential hypertension. | lerated better than propranolol by the patients. | 2634703 | [
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Quaternary structure of the immunostimulating complex (iscom). | Proteins of either HIV-1; hepatitis B; or rabies virus were incorporated with the adjuvant substance Quil A and cholesterol into the immunostimulating complex: iscom. Formation and symmetry of this regular complex were analyzed by electron microscopy. Micellar structures with a diameter of about 12 nm; occasionally with a 7-nm stain-filled center; were formed in a 0.03% water suspension of Quil A. Cavities or holes appeared in the smooth structures of cholesterol upon the addition of Quil A; and after mixin | 2634709 | [
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Quaternary structure of the immunostimulating complex (iscom). | g Quil A and cholesterol 1:1 fragile and flattened structures of matrix were produced with a diameter of about 40 nm. By freeze-drying the matrix was preserved as a cage-like; isometric particle. Stable iscom particles composed of Quil A; cholesterol; and selected viral proteins had an approximate diameter of 32 nm. The particles had an uniform; cage-like structure; exhibiting icosahedral symmetry; irrespective of the viral proteins incorporated. Tilting experiments and rotational image analysis indicated t | 2634709 | [
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Quaternary structure of the immunostimulating complex (iscom). | hat the iscoms were composed of 20 morphological subunits assembled in a pentagonal dodecahedron with a hole on each of the 12 pentagonal faces. The symmetrical shape of the iscom might explain both its remarkable stability and its capacity to efficiently present antigens to the immune system. | 2634709 | [
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Scanning transmission electron microscopic study of molluscan hemocyanins in various aggregation states: comparison with light scattering molecular weights. | The masses of individual particles of the hemocyanins of six members of two molluscan classes; Polyplacophora and Gastropoda; have been determined by scanning transmission electron microscopy (STEM) of unstained specimens dried from the frozen state. The decameric hemocyanins of two chitons; Mopalia muscosa and Stenoplax conspicua; had masses of 4.20 +/- 0.18 and 4.47 +/- 0.56 MDa; respectively; the didecameric hemocyanins of two gastropods; Fasciolaria tulipa and Pleuroploca gigantea; had masses of 8.67 +/ | 2634708 | [
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Scanning transmission electron microscopic study of molluscan hemocyanins in various aggregation states: comparison with light scattering molecular weights. | - 0.44 and 8.96 +/- 0.39 MDa; respectively; and the tridecameric hemocyanin of Lunatia heros had a mass of 13.50 +/- 0.44 MDa. The STEM values were in close agreement with those obtained by light scattering measurements of the same samples in solution. For Busycon contrarium; a gastropod with a multidecameric hemocyanin; nine size classes from didecamers to decadecamers with masses that corresponded to multiples of a basic decamer (4.4 MDa) were detected. The appearance of unstained specimens of the cylindr | 2634708 | [
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] |
Scanning transmission electron microscopic study of molluscan hemocyanins in various aggregation states: comparison with light scattering molecular weights. | ical particles differs from negatively stained specimens. Viewed end-on the cylinders show no internal structure; but in well-preserved specimens cavities are apparent in the side views of the cylinders that resemble those seen in negatively stained specimens. Although they lack the characteristic "tiered" appearance; the number of decameric units can be counted and their arrangement within the particle seen. | 2634708 | [
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Cellular polarity in cultured animal pole cells of Xenopus embryos. | The expression of intracellular and surface polarity in cultured animal pole cells of Xenopus embryos (stages 6; 8; and 10) was examined morphologically and immunocytochemically. When control embryos reached stage 23; daughter cells derived from a single or a few animal pole cells formed aggregates. Outer cells of the aggregates displayed intracellular and surface polarity and expressed an epidermis-specific antigen (XEP-1) on the apical surface circumference; while these characteristics had not yet been es | 2634710 | [
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Cellular polarity in cultured animal pole cells of Xenopus embryos. | tablished in the animal pole cells at the time of isolation. However; inner cells of the aggregates did not display the cellular polarity along an outer-inner axis of the aggregates and displayed the antigen randomly within the aggregates. These results indicate that the expression of cellular polarity in epidermal differentiation of Xenopus embryos in vitro depends on the position within the aggregates formed by daughter cells derived from isolated animal pole cells. | 2634710 | [
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The role of non-sterile gloves in clinical practice. | The role of gloves as part of the overall control of cross-infection in dental practice is examined. The case for the wearing of gloves is made; and the paper also deals with glove material; single or multiple use; hand protection; adverse reactions; and advice on glove use. | 2634712 | [
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A retrospective cephalometric study of the effects of the Harvold appliance in the treatment of 20 patients with a Class II division 1 malocclusion. | The aim of the study was to investigate the effects of the Harvold appliance on the dentoalveolar and skeletal structures and note the changes produced. The primary impact of the Harvold appliance as shown in this study was dentoalveolar. | 2634713 | [
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The causes of tooth mortality of permanent teeth in a Malaysian population. | The reasons underlying the need for extraction of 2765 permanent teeth carried out over a 6 month period in the Out-patient Clinic in the Dental Faculty; University of Malaya; was investigated. The present study showed that dental caries (67.4%) is the leading cause for extraction followed by periodontal disease (19.6%). Caries accounted for the highest proportion of extractions up to the age of 50 whereas periodontal disease becomes the major factor beyond this age. The highest frequency of extractions car | 2634714 | [
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The causes of tooth mortality of permanent teeth in a Malaysian population. | ried out was between the ages of 21-30. | 2634714 | [
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The effect of heterologous gonadotropins on the fecundity of rhesus monkeys. | Ovarian stimulation with heterologous gonadotropins over a period of a single month did not depress the fecundity or fecundability of 50 rhesus monkeys as compared to 60 untreated monkeys in a timed breeding colony. The birth rates; seasonality of births; interbirth intervals; and waiting time to the next pregnancy were not significantly different before treatment; after treatment; or among the untreated. The stillbirth rate was not increased after treatment. | 2634719 | [
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Surgical treatment of iliofemoral vein thrombosis technical aspects. Possible secondary interventions. | From October 1982 to February 1989 148 patients underwent venous thrombectomy. Priority for surgery was given especially in patients under 40 years with posttraumatic; postoperative and postpartum thrombosis where lysis was not possible. Our standardized operative technique includes atraumatic exposure of the vessels; clot extraction by balloon catheter and ring stripper; endoscopic control of the lumen and establishment of a temporary arteriovenous fistula. Postoperative angiography revealed that more than | 2634715 | [
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Surgical treatment of iliofemoral vein thrombosis technical aspects. Possible secondary interventions. | 10% of the patients needed secondary dilatation of iliac vein stenosis which can be carried out easily at the time of closing the fistula. Functional and anatomical parameters as well as the clinical outcome after 12 months show good to excellent results which confirm venous thrombectomy as a useful treatment modality at an acceptable risk level. | 2634715 | [
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Thromboembolism. Clues for the presence of occult neoplasia. | It has been stated that it is inappropriate to conduct an extensive search for occult malignancy in patients with thromboembolism; unless there is some more specific indication. The present study defines those specific indices. By analyzing the clinical features of 11 consecutive patients with occult cancer presenting with thromboembolism (TE); criteria which differentiate TE in occult cancer from TE complicating other disorders were defined. These are the absence of an apparent cause for the TE at the time | 2634716 | [
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Thromboembolism. Clues for the presence of occult neoplasia. | of the patient's admission; age more than 50 years; multiple sites of venous TE; associated venous and arterial TE; TE resistant to therapy with oral anticoagulants; and the presence of associated paraneoplastic syndromes. The incidence of these parameters in case reports from the literature was also analyzed. The six criteria that were prevalent in our series of patients with paraneoplastic TE; were observed to occur with similar incidence in different groups of historical cases. These criteria may be use | 2634716 | [
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Thromboembolism. Clues for the presence of occult neoplasia. | ful for stratification of patients with TE with regard to the probability of the presence of an occult cancer and the indications for further investigations. | 2634716 | [
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Normal fertilization in men with high antibody sperm binding by the addition of sufficient unbound sperm in vitro. | A high incidence of fertilization failure has been reported in men with over 70% of their sperm bound with isoantibodies. In three men with greater than 80% antisperm antibody binding with IgG and IgA immunoglobulins; a normal rate of fertilization (29/46 oocytes; 63%) was achieved by adding a sufficient number of motile sperm to provide at least 50;000 unbound sperm per oocyte. This method appears to be simpler and more effective than attempting to separate unbound sperm in vitro. | 2634720 | [
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Thromboendarterectomy (TEA) in the recipient as a major risk of arterial complication after kidney transplantation. | The authors analyze a series of 383 kidney transplantation pointing out the role of recipient's vessels atherosclerosis in the determination of vascular complication of the kidney graft. Three groups were considered. The first included 55 patients which required TEA for severe atherosclerotic lesion of the anastomosed vessels. The second group included 305 patients who didn't required TEA; the third group was of 20 patients who received a graft with multiple arteries which required more than one anastomosis | 2634717 | [
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Thromboendarterectomy (TEA) in the recipient as a major risk of arterial complication after kidney transplantation. | . A significative higher rate of arterial complications was evident in the first group (p less than 0.001). Within this group the end to end arterial anastomosis was more frequently associated to thrombosis or stenosis than the end to side one (p less than 0.05). Kidney with multiple vessels also presented with an higher rate of complications (p less than 0.05). | 2634717 | [
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Single- and double-lumen needles for oocyte harvesting. | nan | 2634721 | [
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The effects of a hydrocolloid dressing on bacterial growth and the healing process of leg ulcers. | Thirty patients with lower extremity ulcers of different aetiologies; although mainly of venous origin; were treated with an occlusive hydrocolloid dressing twice a week for a maximum period of 12 weeks. No antibacterial chemotherapy was utilized. A culture was taken of the exudate of the ulcer before commencement of treatment and weekly or bi-weekly thereafter. The results showed a mixed flora with prevalence of Staphylococcus aureus. The average duration of the treatment period was 67 +/- 11 days with a t | 2634718 | [
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The effects of a hydrocolloid dressing on bacterial growth and the healing process of leg ulcers. | otal of 26 patients being healed by the end of this period. The average interval between dressing changes was 4.1 days. Subsequent bacterial cultures showed a persistence of the original flora; but there was no correlation between the type of flora present and clinical evidence of infection or between the type of flora present and the rate of healing of the ulcer. Clinical evaluation of the results obtained with the hydrocolloid dressing was favourable in respect to reduced risk of contamination of the ulce | 2634718 | [
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The effects of a hydrocolloid dressing on bacterial growth and the healing process of leg ulcers. | r; lower pain perception and less trauma to the granulation tissue during dressing changes. | 2634718 | [
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How information-gathering, its documentation, its communication, and a heads-up philosophy can reduce your exposure to malpractice claims and help you serve your patients more completely. | nan | 2634723 | [
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Fasting serum gastrin values in normal Chinese children. | To determine the reference ranges and developmental pattern of serum gastrin in Chinese children; fasting serum samples of 362 Chinese infants and children aged from newborns to 14 years were measured by radioimmunoassay. All the participants were healthy and were without gastrointestinal disorders. The mean gastrin values for cord blood (111.55 +/- 68.05 pg/ml) and newborns (100.05 +/- 72.43 pg/ml) are higher than those for adult controls (43.85 +/- 15.59 pg/ml). The mean gastrin value achieves its highest | 2634726 | [
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Fasting serum gastrin values in normal Chinese children. | level of 179.86 +/- 94.61 pg/ml on the 3rd day of age. Physiologic hypergastrinemia persists throughout the whole neonatal period. The mean gastrin value for infants between 6 days and 6 months of age is 96.08 +/- 50.05 pg/ml; this decreases to 76.73 +/- 44.23 pg/ml at 7 to 12 months of age; and to 75.89 +/- 43.88 pg/ml at 1 year of age. It reaches the low adult level (40-45 pg/ml) at about 2 years of age. | 2634726 | [
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Comparison of penile vascular effect induced by intracavernous injection of papaverine and prostaglandin E1. | An intracavernous injection with papaverine or prostaglandin E1 (PGE1) combined with duplex ultrasonography is an objective technique to conduct a penile blood flow study (PBFS). Three hundred patients with impotence underwent papaverine (9-60 mg) induced PBFS at the University of California School of Medicine; San Francisco (UCSF); U.S.A. and another 80 patients with impotence received PGE1-induced (20 micrograms) PBFS at Veterans General Hospital-Taichung (VGH-TC); R.O.C. Preliminary evaluation of age; du | 2634727 | [
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Comparison of penile vascular effect induced by intracavernous injection of papaverine and prostaglandin E1. | ration of disease and pre-injection diameter of cavernous arteries disclosed no significant difference in these 2 series. It was interesting to find that almost all parameters of vascular response to pavaverine vs PGE1 differed significantly; such as onset of response (6.5 +/- 6.5 vs 11.7 +/- 6.4 min; slower in the PGE1 group; p less than 0.001); post-injection diameter of cavernous arteries (right: 0.73 +/- 0.20 vs 0.79 +/- 0.18 mm; p = 0.03; left: 0.74 +/- 0.20 vs 0.82 +/- 0.21 mm; p = 0.005); diametral i | 2634727 | [
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] |
Comparison of penile vascular effect induced by intracavernous injection of papaverine and prostaglandin E1. | ncrement of cavernous arteries (right: 0.23 +/- 0.17 vs 0.33 +/- 0.17 mm; p less than 0.001; left: 0.24 +/- 0.17 vs 0.36 +/- 0.19 mm; p less than 0.001) and peak velocity (right: 27.5 +/- 16.1 vs 42.0 +/- 20.1 cm/sec; p less than 0.001; left: 28.9 +/- 15.9 vs 39.7 +/- 17.9 cm/sec; p less than 0.001). The side effects; primarily injection pain (23.8%; 19/80) in the PGE1 group and dizziness (3.0%; 9/300) in the papaverine group; were minor in these 2 series. Prolonged erection was not encountered in either se | 2634727 | [
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Comparison of penile vascular effect induced by intracavernous injection of papaverine and prostaglandin E1. | ries; however; immediate treatment was performed if a papaverine-induced erection lasted over 60 minutes.(ABSTRACT TRUNCATED AT 250 WORDS) | 2634727 | [
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Surgical management of congenital coronary artery fistula. | Over a period of 6 years; 8 patients underwent surgical treatment at our hospital for congenital coronary artery fistula (CAF). The ages of the patients ranged from 4 months to 50 years (mean 22.7 years). Continuous heart murmurs could be heard in all patients; except one. The diagnosis was made by retrograde aortography and/or selective coronary arteriography. Only one patients had associated cardiac disease. All the drainage sites of the CAF were on the right side of the heart (right atrium; right ventric | 2634728 | [
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Surgical management of congenital coronary artery fistula. | le; pulmonary artery). Two patients had both right and left CAFs. Symptoms due to "coronary steal" by a coronary artery fistula were demonstrated by a nuclear medicine study in one of our patients. Four patients were operated on with the aid of cardiopulmonary bypass. The other 4 patients were treated with suture ligation directly. There was no surgical mortality or morbidity; and the longterm results have been good. Since surgical correction is safe and effective; it would appear desirable for all patients | 2634728 | [
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Surgical management of congenital coronary artery fistula. | with CAF be operated on. However; surgical intervention is controversial in asymptomatic patients. | 2634728 | [
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Acute primidone intoxication: report of a case. | A case of acute primidone intoxication; due to overdose; was evaluated at National Taiwan University Hospital. Serial assessment of the clinical manifestations; electroencephalograms and serum levels of primidone and phenobarbital were made. From these data; we conclude that the toxic effects; such as depression of the central nervous system and dysequilibrium; are due mostly to primidone itself; rather than its metabolite; phenobarbital. | 2634729 | [
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Paradoxical enlargement of intracranial tuberculomas during treatment of tuberculous meningitis: report of a case. | We report a case of a 32-year-old man who showed paradoxical enlargement of pathologically verified intracranial tuberculomas during a course of adequate antituberculous chemotherapy. Serial computed tomographic scans of the brain disclosed this uncommon phenomenon. Total excision of the lesions with concomitant four-combined antituberculous therapy proved successful. Although the mechanism of this paradoxical phenomenon is not well understood; a defective local tissue immune response with gradually increas | 2634730 | [
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Paradoxical enlargement of intracranial tuberculomas during treatment of tuberculous meningitis: report of a case. | ing maturity of the lesions during antituberculous therapy; which results in poor penetration of these drugs into the lesions; might be a possible explanation. | 2634730 | [
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[Surgical treatment of ureteropelvic junction stricture]. | Forty-five patients with hydronephrosis due to pelviureteric junction stricture were operated on at Kaohsiung Medical College Hospital between 1971 and 1986. In unilateral cases; the left kidney was affected more frequently than the right (24 to 13); while 8 (18%) had bilateral ureteropelvic stricture. Of the 45 cases; 24 cases (53%) underwent Anderson-Hynes pyeloplasty; 5 cases underwent Y-V plasty; 5 cases underwent ureterolysis and 11 cases underwent simple nephrectomy due to severe hydronephrosis. Excep | 2634731 | [
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[Surgical treatment of ureteropelvic junction stricture]. | t for the 11 nephrectomy cases; 11 of the remaining 34 cases had ureteral catheter placement and 9 cases had double-J ureteral catheter placement; postoperatively; another 14 cases received no ureteral stent for draining urine. The results were very encouraging with clinical improvement in 64% of the patients; and improvement in the pelviocaliceal system and early appearance of contrast medium in the ureter in 47% of the patients. The results of pyeloplasty with and without a nephrostomy or ureteral stent w | 2634731 | [
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[Surgical treatment of ureteropelvic junction stricture]. | ere compared. Patients with a nephrostomy or ureteral stent tended to have an increased incidence of urinary tract infections and longer hospital stays. In general; the results of treatment were poorer for patients with a nephrostomy or ureteral stent; than for patients without. | 2634731 | [
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Effect of estrogen on platelet aggregation in guinea pigs. | This experiment was carried out to explore the effect of estrogen on platelet aggregation; using Hartly strain guinea pigs. For the in vivo experiments; estradiol benzoate 1 mg/kg or 4 mg/kg was injected into male guinea pigs to observe the effects of this drug on platelet aggregation. In vitro studies were performed by incubating platelet-rich plasma with estradiol benzoate for 30 minutes at 37 degrees C. Aggregation was induced by the addition of aggregating agents: adenosine diphosphate (ADP; lobster or | 2634732 | [
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Effect of estrogen on platelet aggregation in guinea pigs. | rabbit muscle; Merck); and collagen (calf skin; Bio-Data). The change in transmittance at 660 nm was recorded using NKK HEMA TRACER 1; model PAT-4A (Nippon Denshi Kagaku Co.; Japan). Our results revealed that a 1 mg/kg injection of estrogen had a statistically significant suppressive effect on both ADP and collagen-induced platelet aggregation. While in the group with the 4 mg/kg injection of estrogen; this suppressing effect was not significant. In vitro studies by incubating platelet-rich plasma with estr | 2634732 | [
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Effect of estrogen on platelet aggregation in guinea pigs. | adiol had no inhibitory effect on aggregation induced by both ADP and collagen. | 2634732 | [
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Effects of monomeric and polymeric diets on small intestine following massive resection. | Since the introduction of long-term total parental nutrition; it has been possible to raise the survival rate in patients with massive intestinal resection. How to increase the remaining intestinal mucosa hyperplasia in these patients has become the focus of many studies. Early postoperative enteral feeding with exogenous intraluminal nutrition was considered to be one of the most essential factors. The best enteral food pattern; however; is still not conclusive. In this study; we used the animal model of r | 2634733 | [
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Effects of monomeric and polymeric diets on small intestine following massive resection. | ats with 60% small intestinal resection; giving them different kinds of enteral diets through gastrostomy tubes. The monomeric diet included amino acid; glucose; disaccharide; and triglyceride. The polymeric diet included the usual source of nutrition such as protein; polysaccharide; and fat. The rats were killed three weeks later. Histopathological changes of the remaining bowel and H3 thymidine incorporation to mucosal DNa were measured. We found: (1) hyperplasia of the remaining bowel in the 60% resected | 2634733 | [
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Effects of monomeric and polymeric diets on small intestine following massive resection. | rats was definitely increased more than the rats of the sham operation; (2) from the protein content; the DNA content of mucosa cells; the villus height and crypt depth points of view; the polymeric diet fed rats had a better adaptation; (3) on the 21st postoperative day; the DNA synthetic rate was still very high in polymeric diet fed rats; but returned to preoperative levels in rats fed with a monomeric diet. Our conclusion of this study is that a polymeric diet can contribute to a better intestinal muco | 2634733 | [
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Effects of monomeric and polymeric diets on small intestine following massive resection. | sa regeneration than a monomeric diet in the rats with massive intestinal resection. | 2634733 | [
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Experimental allograft in spinal fusion in dogs. | Fifty-six dogs were used for the comparison of the allogenous and autogenous bone graft in anterior interbody and posterior spinal fusion. Excluding 7 cases with wound infections; the end results of the allograft and autograft in anterior interbody and posterior spinal fusion were nearly the same; provided that the rules of technique for the spinal fusion were strictly followed; especially in the allograft group. Grossly; there was a reduction tendency in the fusion mass of the allograft group that was prov | 2634734 | [
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Experimental allograft in spinal fusion in dogs. | en by roentgenographic examination of the harvested spinal block. Histologically; there was no evidence of regeneration of the allograft that can be readily detected in the autograft. In the allograft group; osteogenesis can only be seen in the recipient sites; the allograft transplants become sequestrated and resorbed. | 2634734 | [
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Increase in negative charge of cytosolic aspartate aminotransferase in vitamin B6 deficiency and during incubation. | Several subforms of cytosolic aspartate aminotransferase (AspATc) in the crude extracts of rat liver and kidney were separated by isoelectric focusing using immunoblotting and staining of activity to detect the enzyme protein and activity; respectively. Vitamin B6-deficiency resulted in decrease in the subforms with higher isoelectric points and increase in those with lower ones both in the liver and in the kidney. When pyridoxal phosphate was added to those preparations from vitamin B6-deficient rats; the | 2634735 | [
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Increase in negative charge of cytosolic aspartate aminotransferase in vitamin B6 deficiency and during incubation. | isoelectric focusing pattern of kidney was recovered to the similar one to that of the controls. However; the liver preparation was affected only partially by the addition of PLP. The pattern of subforms was altered during in vitro incubation at 37 degrees C for 24 h in both liver and kidney preparations; and their patterns were very similar to that of liver preparation from VB6-deficient rats. The enzyme activity also decreased during this incubation; especially in preparations of the enzyme from the liver | 2634735 | [
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Increase in negative charge of cytosolic aspartate aminotransferase in vitamin B6 deficiency and during incubation. | of vitamin B6-deficient rats. This loss of enzyme activity was not affected by addition of PLP alone; but was almost completely prevented by addition of substrate. The inactivation was recovered by addition of substrate and pyridoxal phosphate simultaneously. This finding suggests that the inactivation may be related with a conformational change around the catalytic site of the AspATc molecule. | 2634735 | [
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Purification, properties, and developmental changes of cellular retinol-binding protein, type II, in chicken intestine. | Two distinct cellular retinol-binding proteins were detected in chicken small intestine. A predominant form was purified to homogeneity. The apparent molecular weight of this protein was estimated to be 17;200. This form was larger than a second minor form partially purified (molecular weight of 15;000). The absorption and fluorescence spectra of the bound retinol to the purified proteins were typical for the known cellular retinol-binding proteins. The results suggest that the purified binding protein corr | 2634736 | [
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Purification, properties, and developmental changes of cellular retinol-binding protein, type II, in chicken intestine. | esponds to CRBP(II); previously identified in small intestine of rats and humans. To gain an insight into the possible role of CRBP(II) in chicken small intestine; the CRBP(II) contents in cytosols of small intestine of embryonic and post-hatch chicks were determined by enzyme-linked immunosorbent assay. The amount of CRBP(II) per unit DNA in small intestine was low at 15- and 17-day embryonic stage; but rapidly increased around the period of hatching. The increased level was still maintained in 6-week-old | 2634736 | [
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Purification, properties, and developmental changes of cellular retinol-binding protein, type II, in chicken intestine. | chicks; which accounted for 0.9% of total proteins in duodenum. The developmental pattern and the presence of abundant amount of CRBP(II) in chicken small intestine supports the hypothesis that CRBP(II) might play some role in the intestinal absorption of retinoids. Thus the involvement of a tissue-specific cellular retinol-binding protein in the intestinal absorption of retinoids appears to be common in mammalian and avian species. | 2634736 | [
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Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats. | Effect of proportion of three branched-chain amino acids (leucine; valine; and isoleucine:BCAA) for nitrogen utilization was studied in vivo by an intragastric administration of 15N-L-leucine to control rats and liver-injured rats treated with carbon tetrachloride (CCl4-rats). Following the administration of isonitrogenous dose of three amino acid solutions [Standard (15N-L-leucine; L-valine; L-isoleucine; and L-alanine; 11; 8; 6; 18 mg/ml); Low-Val (11; 2; 6; 23 mg/ml); and High-Val (11; 32; 6; 0 mg/ml)]; | 2634737 | [
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Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats. | 15N enrichments in serum albumin; liver; skeletal muscle; and brain proteins and non-protein fractions; and urea nitrogen were compared by using 15N-analyzer. In CCl4-rats; the 15N enrichment in liver protein fraction was significantly lower in the High-Val group than in the Low-Val group. However; the difference of 15N enrichment in serum albumin between Low-Val and High-Val groups in CCl4-rats was unclear. The 15N enrichments in non-protein fractions of the brains in CCl4-rats were about twofold those in | 2634737 | [
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Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats. | the skeletal muscles and the highest 15N enrichment was recognized in the Low-Val group. In the non-protein fraction of skeletal muscle in CCl4-rats; significantly low 15N enrichment was shown in the High-Val group compared with the Low-Val group. The 15N enrichment in urinary urea was significantly higher in the High-Val group than in the Low-Val group in CCl4-rats. In the Standard group of control rats; 15N enrichments in serum albumin and protein fraction of skeletal muscle were higher than in other grou | 2634737 | [
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Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats. | ps. In non-protein fractions of control rats; the lowest 15N enrichment in liver and the highest 15N enrichment in skeletal muscle were recognized in the Standard group. These results suggest that a large amount of valine supplement among BCAA is less useful for leucine utilization in liver-injured rats than in normal rats. | 2634737 | [
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Spontaneous and luminol-dependent chemiluminescences from tissue preparations of benzo[a]pyrene-injected mice. | Chemiluminescence (CL) from tissue preparations of mice i.p. injected with and without the chemical carcinogen benzo[a]pyrene (BP) was detected by a single photon counting apparatus. The spontaneously emitted CL (spontaneous CL) and the CL after luminol addition (luminol-CL) were measured for mice with and without previous induction of their liver mixed-function oxidases (MFO) by phenobarbital. In MFO-non-induced mice; although the spontaneous CL was not notably modified by BP injection; the kidneys present | 2634738 | [
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Spontaneous and luminol-dependent chemiluminescences from tissue preparations of benzo[a]pyrene-injected mice. | ed three times greater luminol-CL after BP injection. On the other hand; MFO-induced mice had higher spontaneous CL of plasma; liver; kidneys; and lungs; as well as higher luminol-CL of liver after BP injection; when compared with the respective MFO-induced but BP-non-injected mice. The luminol-CL of liver was suppressed by scavengers of active oxygen and free-radicals such as TIRON; butylhydroxytoluene and in a less extent by superoxide dismutase. The CL detected from tissue preparations of mice after BP t | 2634738 | [
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