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Hyperkalaemia is a life-threatening electrolyte disorder that can occur in the first week of life in almost 50% of preterm infants with a birth weight less than 1000 g [extremely low birth weight (ELBW)].
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They are also underdiagnosed and undertreated.
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BACKGROUND: Coagulation disorders can cause intracerebral bleeding that may be difficult to detect since subsequent aberrant clot formation may mask early detection.
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We report a case of interstitial pneumonitis induced by bicalutamide and/or leuprorelin acetate given as therapy for prostate cancer, in which the pneumonitis was successfully managed by steroid treatment.
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Nitrofurantoin-induced lung disease: two cases demonstrating resolution of apparently irreversible CT abnormalities.
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CASE REPORT: A 37-year-old white female patient admitted with epigastric pain and heartburn symptoms.
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These effects were maintained for the remainder of the patient's chemotherapy protocol.
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Thirty minutes after an anti-drug administration through the chest drainage tube, he lost consciousness shortly after coughing.
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A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome.
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Broncho-pulmonary infection in a 50-year-old male with acute, hypertensive, intracerebral bleeding, necessitated therapy with cefpirome (2 g/day, 6 days), ciprofloxacin (800 mg/d, 11 days) and tazobactam/piperacillin (9 g/day, 11 days).
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We present a brief review of the mechanism of action of TNF-alpha antagonists and their ability to predispose to various infections including viral pneumonia by interfering with the immune response.
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They conclude that the vascular surgeon should be aware of this possibility and that oral anticoagulants should be used very carefully in the "medical" management of cholesterol embolization.
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The occurrence of neuromuscular blockade and the resulting potentiation of muscle relaxants during magnesium sulfate (MgSO4) administration is well known.
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At 8 months after surgery, hair again covered his entire head.
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Spontaneous coronary artery dissection is an unusual cause of acute myocardial ischemia.
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In both cases there was a progressive increase during treatment, in peripheral blood lymphocyte counts, skin reactions and in vitro cellular responses to PPD, and a sudden rise in ESR at the time of their deterioration.
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Tiny black granules were most numerous in the basal laminae of vessels in electron microscopic observation.
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An infant girl with choanal atresia, athelia, minor anomalies, and mild to moderate mental retardation was born to a woman treated for hyperthyroidism throughout pregnancy with methimazole and propranolol.
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Levofloxacin induced polymorphic ventricular tachycardia with normal QT interval.
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Drug-induced agranulocytosis during treatment with infliximab in enteropathic spondyloarthropathy.
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Dental and gingival pain as side effects of niacin therapy.
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Cultures from the site of corneal abscess and vitreous grew coagulase-negative Staphylococcus.
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Acute asymptomatic hepatitis in a healthy normal volunteer exposed to 2 oral doses of amodiaquine and artesunate.
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Complications of encephalitis of unknown origin were successfully treated with steroid therapy and the patient has been in CR for 16 months after BMT.
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In one patient after three tablets of Mexase a clioquinol concentration of 12 microgram/ml in plasma was found 24 hours after the specified dose, which is an unexpectedly high concentration compared to those reported as late as 24 hours after a single equal dose of Mexase or any other clioquinol-containing preparation.
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Adverse effects of propafenone after long-term therapy with the addition of citalopram.
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Torsades de pointes was diagnosed in the Emergency Department (ED).
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We report the case of a young HIV seropositive patient with severe hemophilia A who presented rapid liver failure related to his chronic C hepatitis.
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Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease.
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Following 7 days of tigecycline she developed severe abdominal pain and elevated pancreatic enzymes suggesting acute pancreatitis.
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Seizures and transient blindness following intravenous pulse methylprednisolone in children with primary glomerulonephritis.
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Subsequently, he developed hyperglycemia (fasting blood glucose 138 mg/dL) that resolved when olanzapine was stopped and recurred (fasting blood glucose 150 mg/dL) after 2 days of rechallenge with olanzapine 2.5 mg twice daily.
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Severe symptomatic hyponatremia during sibutramine therapy: a case report.
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There are a few case reports of other fluoroquinolones that have been associated with toxic epidermal necrolysis.
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CONCLUSIONS: Mycobacterial keratitis is a potentially vision-threatening complication after LASIK, characterized by a long latent period, delayed diagnosis, and a protracted course even under intensive specific antibiotic therapy.
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A positive rechallenge occurred in seven cases (20%).
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Furthermore, the concomitant use of fluoxetine and clozapine is discouraged, with citalopram suggested as a suitable antidepressant in those depressed patients receiving clozapine.
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Based on these properties, GIRK activators have been suggested as candidates for antiepileptic drug development.
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One twin had clinically appreciable hypoparathyroidism and had received calcitriol since early infancy.
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Obidoxime was reinstituted after the 9 d interruption and muscle strength improved with the first dose.
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A 65-year-old woman with bipolar disorder and complicated cardiovascular disease who was on maintenance lithium therapy developed a movement disorder following high doses of trazodone for treatment of an acute depression.
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Early-onset acute transverse myelitis following hepatitis B vaccination and respiratory infection: case report.
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Corticosteroid management of airway hemangiomas: long-term follow-up.
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We have reported the first case of successful treatment of disseminated histoplasmosis in a renal allograft recipient using a short course (14 days) of amphotericin B in combination with prolonged therapy (161 days) with ketoconazole.
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Two children, one with renal manifestations of systemic lupus erythematosus and the other with idiopathic nephrotic syndrome, were treated with methylprednisolone pulses.
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A 64-year-old woman with blepharospasm, sustained clenching of the jaw, antecollis, and a strained, high-pitched phonation continued chronic trihexyphenidyl therapy despite the lack of any obvious benefit.
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He developed hyperpyrexia with oligohidrosis and central neurological symptoms, including, chorea-like involuntary movements, resting tremor, and cogwheel rigidity.
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Phenytoin toxicity and thyroid dysfunction.
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Even though the pathogenic mechanism of acute leukemia after cytotoxic treatment is not known, the possibility must be considered that the incidence of this malignant disease is increased after cytotoxic treatment for nonmalignant diseases.
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Seven months after treatment onset, a combination of nortriptyline, clonazepam, and relaxation procedures has successfully controlled the patient's facial pain symptoms.
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False positive results due to cross-reactive compounds in drug assays may lead to misdiagnosis and mismanagement, especially when child abuse is suspected.
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The intensive care unit (ICU) represents a dynamic interaction between patient factors and interventional factors.
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A patient is presented with typical hyperthyroidism, who developed a severe proximal muscle weakness and a raised creatine phosphokinase after treatment for hyperthyroidism with propylthiouracil (100 mg orally, three times a day).
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This report describes our experience with four adult patients who suffered anthracycline extravasation and were treated with a regimen of ice, local glucocorticoid injection, and dimethylsulfoxide (DMSO) 55%-99% applied topically every 2-4 h after extravasation for a minimum of 3 days.
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Thiazolidinedione drugs are in widespread use for the treatment of type 2 diabetes.
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RESULTS: Bimatoprost was discontinued and diclofenac initiated.
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He recovered after administration of anti-histamines and steroids.
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With many HIV-infected patients surviving alkylator and topoisomerase inhibitor-based treatment and radiation therapy for AIDS-defining cancers and NADCs, long-term follow-up for therapy-related complications assumes greater importance.
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Diagnosis of lipoid pneumonia was made by diagnostic bronchoscopy with bronchoalveolar lavage (BAL).
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Terlipressin was discontinued, and the patient's QTc interval subsequently returned to baseline.
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The chemotherapeutics, including vincristine, actinomycin D, and epirubicin in case 1 and vincristine and actinomycin D in case 2, were given before the hepatotoxicity developed.
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The evidence for this mechanism is not convincing.
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Four months later, she continued to exhibit decreased fluency and dysarthria with ataxia.
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The time course of events suggested that amphotericin B was the cause of the seizures in this AIDS patient.
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We report a case of symphysitis causing hospitalization and severe pain and discomfort of the patient.
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The uncontrolled case report: a double-edged sword.
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At five years of age elevated serum and urinary androgen levels unsuppressible with dexamethasone were noted.
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The mechanism by which sunitinib induces gynaecomastia is thought to be associated with an unknown direct action on breast hormonal receptors.
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This case and others indicate that caution should be exercised in administering IFN because low doses can be correlated with myasthenia gravis in patients without malignancies.
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Primary ovarian large B-cell lymphoma in patient with juvenile rheumatoid arthritis treated with low dose Methotrexate.
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Her serum creatinine was elevated to 2.2 mg/dl (baseline 1.5 mg/dl), and trough tacrolimus level was markedly elevated (> 30 ng/ml).
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A 67 year old man presented to his local dentist for restorative treatment.
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Finally a renal biopsy was performed and it showed a pauci-immunologic glomerulonephritis and the bronchioloalveolar lavage confirmed the diffuse alveolar hemorrhage.
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Liver biopsy showed bridging hepatocellular necrosis as well as canalicular cholestasis.
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Patients typically have surgical rhinoplasty to correct unsightly noses resulting from trauma, surgery, or heredity.
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With the immunocompromised patient it is important to seek early ophthalmologic consultation when even minor ocular symptoms develop.
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Antipsychotic-induced RLS and PLMS are not well-recognized side effects of antipsychotics, with the symptoms often misdiagnosed as psychotic agitation.
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Because of the presence of severe ascites and massive ovarian enlargement, it was elected to treat this patient with methotrexate therapy rather than surgery.
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The diagnosis of destructive thyroiditis was confirmed by anti-TSH receptor antibody (TSHRAb) negativity and the absence of radionuclide ((123)I or (99)Tc) uptake on thyroid scintiscans.
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The second patient, a 39-year-old man, showed endophthalmitis of the right eye.
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Baclofen withdrawal syndrome resulting from underdosing of oral baclofen should be considered as a potential source of prolonged fever in the intensive care unit.
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OBJECTIVE: To report a case of Carbamazepine toxicity following the administration of Oxybutynin and Dantrolene.
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OBJECTIVES: Successful excision of the mass and identification of the causative agent by histologic and microbiologic studies.
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Trimethoprim-sulfamethoxazole-induced hypersensitivity syndrome associated with reactivation of human herpesvirus-6.
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A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency who developed a syringotropic hypersensitivity reaction after 9 months of therapy with infliximab and leflunomide is described.
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Methamphetamine's extensive physiologic effects, inconsistent street purity, and multiple routes of administration offer many possibilities for injury to the cornea.
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A 66 year old HIV infected male heavy smoker presented with arthralgia, myalgia, and weight loss which was originally ascribed to nucleoside induced mitochondrial toxicity.
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The optimal management of anthracycline extravasation remains unclear.
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We describe a 66-year-old woman with chronic paranoid schizophrenia who was prescribed olanzapine along with several other psychiatric drugs and an antihypertensive drug.
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Our report highlights the importance of taking a detailed occupational history and considering lead poisoning in the differential diagnosis of acute abdominal colic of unclear cause.
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The patient recovered well after surgical drainage and antimicrobial therapy.
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Hypotension and sinus arrest with nifedipine in pulmonary hypertension.
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We report an example of ACC and review the relevant literature.
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The lactic acidosis occurred in the absence of mitochondrial myopathy, hepatomegaly, or liver failure.
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This article demonstrates that POS may be a useful drug in mucormycosis in children.
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STUDY DESIGN: Case report of a 31-year-old woman who presented with toxic myelopathy due to intrathecal administration of doxorubicin.
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To increase the drug concentration at the infection site, we irrigated the capsular bag with antibiotics.
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OBJECTIVE: To describe and discuss the use of continuous intravenous infusions of haloperidol to treat severe delirium and agitation in 3 intensive care unit (ICU) patients.
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OBJECTIVE: To describe a case of exacerbated mania potentially related to an interaction between lopinavir/ritonavir and valproic acid (VPA) and propose a mechanism of action for this interaction.
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Emphasis is placed on the significance of the possible relationship and similarity between NIS and catatonic stupor, and on the theoretical possibilities which this offers.
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