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Q: Does $N_{r-1}\subset N_r$ or $N_r\subset N_{r-1}$? Let $r\in\mathbb{N}$ and $0<\lambda_1\dots\lambda_r<\dots$ be a sequence of eigenvalues and let $E_{r}$ the corresponding eigenspaces. We denote $$N_r =\oplus_{i=1}^r E_i\qquad\mbox{ and }\qquad M_r = (N_r)^{\perp}.$$ My question is: it is possible to determine some relation of inclusions between the spaces $N_r$ and $M_r$? I mean, does an inequality like $N_{r-1}\subset N_r$ or $N_{r}\subset N_{r-1}$ hold? Similarly, we can say something about the spaces $M_r$. Intuitively, I would say that $N_{r-1}\subset N_r$ and $M_r\subset M_{r-1}$ hold, but I would like to prove it. Could someone help me or give me a reference? Thank you in advance! A: Obviously $N_{r-1}\subset N_r$ because for $v$ in the direct sum we have $v=e_1+...+e_r$, take $e_r=0$ then we get $N_{r-1}$. The inequality is strict because eigenspaces are nonempty and disjoint. Let $v\in M_{r}$. Then $v$ is orthogonal to everything in $E_1,...,E_r$. So $v$ is orthogonal to everything in $E_1,...,E_{r-1}$. Therefore $M_r\subseteq M_{r-1}$. The equality case it not clear, it depends on the field because of the Spectral theorem. On a complex vector space, an orthonormal basis of eigenvectors exists if and only if the operator is normal. So if the operator is not normal, we cannot guarantee $M_r\neq M_{r-1}$ (is that clear?)
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How Does the Silverlight Client Talk to the Server in a 3 Tier Lightswitch Application? LightSwitch HTML Client (VS2013 Update 4) - how to hide column programmatically? Does Lightswitch HTML support full-fledged web application development? Lightswitch 2012 was dead... Had to upgrade to 2013,this caused a heap of breaks, but eventually I got it publishing. How do I Allow an Active Directory group member to do anything in my LightSwitch HTML Client application? LightSwitch HTML Client: How to get the content/value of a custom control? It is possible that your custom save button is causing the problem. Any chance you could implement the beforeApplyChanges event and handle any updates there? Out of the box Light Switch HTML app has a null error in IE9? Query in light switch returns only one line? How to make my lightswitch application available to the internet?
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namespace swift { class ASTContext; class TypeRepr; /// TypeLoc - Provides source location information for a parsed type. /// A TypeLoc is stored in AST nodes which use an explicitly written type. class alignas(1 << TypeLocAlignInBits) TypeLoc { Type Ty; TypeRepr *TyR = nullptr; public: TypeLoc() {} TypeLoc(TypeRepr *TyR) : TyR(TyR) {} TypeLoc(TypeRepr *TyR, Type Ty) : TyR(TyR) { setType(Ty); } bool wasValidated() const { return !Ty.isNull(); } bool isError() const; // FIXME: We generally shouldn't need to build TypeLocs without a location. static TypeLoc withoutLoc(Type T) { TypeLoc result; result.Ty = T; return result; } /// Get the representative location of this type, for diagnostic /// purposes. /// This location is not necessarily the start location of the type repr. SourceLoc getLoc() const; SourceRange getSourceRange() const; bool hasLocation() const { return TyR != nullptr; } TypeRepr *getTypeRepr() const { return TyR; } Type getType() const { return Ty; } bool isNull() const { return getType().isNull() && TyR == nullptr; } void setInvalidType(ASTContext &C); void setType(Type Ty); TypeLoc clone(ASTContext &ctx) const; friend llvm::hash_code hash_value(const TypeLoc &owner) { return llvm::hash_combine(owner.Ty.getPointer(), owner.TyR); } friend bool operator==(const TypeLoc &lhs, const TypeLoc &rhs) { return lhs.Ty.getPointer() == rhs.Ty.getPointer() && lhs.TyR == rhs.TyR; } friend bool operator!=(const TypeLoc &lhs, const TypeLoc &rhs) { return !(lhs == rhs); } }; } // end namespace llvm #endif
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package org.bigtester.ate.xmlschema; import org.apache.commons.lang3.StringUtils; import org.bigtester.ate.GlobalUtils; import org.bigtester.ate.constant.XsdElementConstants; import org.bigtester.ate.model.page.atewebdriver.MyChromeDriver; import org.eclipse.jdt.annotation.Nullable; import org.springframework.beans.factory.BeanDefinitionStoreException; import org.springframework.beans.factory.support.AbstractBeanDefinition; import org.springframework.beans.factory.support.BeanDefinitionBuilder; import org.springframework.beans.factory.xml.AbstractSingleBeanDefinitionParser; import org.springframework.beans.factory.xml.ParserContext; import org.w3c.dom.Element; // TODO: Auto-generated Javadoc /** * This class SimpleDateFormatBeanDefinitionParser defines .... * * @author Jun Yang * */ public class ChromeDriverBeanDefinitionParser extends AbstractSingleBeanDefinitionParser { /** * {@inheritDoc} */ protected Class<MyChromeDriver> getBeanClass(@Nullable Element element) { return MyChromeDriver.class; } /** * {@inheritDoc} */ protected void doParse(@Nullable Element element, @Nullable BeanDefinitionBuilder bean) { // this will never be null since the schema explicitly requires that a // value be supplied if (bean == null || element == null) throw GlobalUtils.createNotInitializedException("element and bean"); String preserveCookies = element .getAttribute(XsdElementConstants.ATTR_CHROMEDRIVER_PRESERVECOOKIES); if (!StringUtils.isEmpty(preserveCookies)) { bean.addConstructorArgValue(Boolean.parseBoolean(preserveCookies)); } String startArguments = element .getAttribute(XsdElementConstants.ATTR_CHROMEDRIVER_START_ARGUMENTS); if (!StringUtils.isEmpty(preserveCookies)) { bean.addConstructorArgValue(startArguments); } } /** * (non-Javadoc) * * @see org.springframework.beans.factory * .xml.AbstractBeanDefinitionParser#resolveId(org.w3c.dom.Element, * org.springframework.beans.factory.support.AbstractBeanDefinition, * org.springframework.beans.factory.xml.ParserContext) */ protected String resolveId(@Nullable Element element, @Nullable AbstractBeanDefinition definition, @Nullable ParserContext parserContext) throws BeanDefinitionStoreException { return "MyWebDriver2"; } }
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This is a true story about the most interesting person you've never heard of: Arthur Cravan, major figure in pre-WWI cutting-edge art circles, was among the greatest mysterious figures of the Twentieth Century. A self-confessed thief, forger, and con-artist, he used a roster of assumed names and false identities. He was known, at various times, as a novelist, poet, painter, art critic, lecturer, publisher, and the lightweight boxing champion of France. Always a rebellious, restless spirit, this dedicated rule-breaker was a political radical whose friendship with Leon Trotsky earned him the surveillance of the U.S. government-even through his immigration to Mexico with his wife, the poet Mina Loy. In 1918, at the age of thirty-one, the fascinating physical giant vanished without a trace, and-despite several supposed sightings over the years-was never seen again. Is it possible that he became the mysterious, reclusive novelist B. Traven, who wrote The Treasure of the Sierra Madre?
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Welcome to the UK Scene, with a quiet spot compared the amount of information poor Mitch had to deal with. So, let's get on with the news in the UK Scene this week. As seen on the TWO forums, there has been some confusion as to the safety and whereabouts of Sweet Saraya. There is a report that she walked into a police station to declare herself fit and well, but unfortunately she didn't return home. There is no point being speculative about the reasons as to why, just that it is taking its toll on Ricky Knight and his family. Not only has their daughter Saraya-Jade collapsed and has been taken into hospital the stress has got to Ricky as he has been hospitalised himself to recover from stress and an alcohol problem. I feel a bit icky being part of washing their problems out in public, but it is good emphasis that you wrestling fans, marks and Smarks alike should realise that we wrestlers are human beings too. Ricky has asked that all the shows he has organised carry on without him while he recovers and we at Wrestling101 wish him and his family our sympathy and good wishes. One of the effected shows will be HEW's refreshingly abrubt "Show number 3" whish will take place on Friday October 21st at The Takeley Silver Jubilee Hall in Takeley, Hertfordshire. The current card looks like this: Simply Luscious vs. Skye vs. Lamia Dave Dearden vs. Nathan Reigns Ricky Relentless vs. Zak Zodiac James Tighe vs. Aviv Maayan The UK Pitbull vs. Saul Adams & Jack Storm, if The UK Pitbulls lose then they will leave HEW Ricky Knight & Andy Simmonz vs. Bash & Paul Travell With Ricky hospitalised the final match will have to be changed, but now you know why cards are always subject to change. Ticket Prices are adults for �10, children for �8 and a family ticket for �30. Doors open: 6:30pm, show starts: 7:30pm The final connection that worries me is that I was wandering around the net and I noticed that the WAW website is temporarily closed. Not good news! FWA are coming up a little shy on news as of late, the only news really of note is Jack Xavier being injured in training. I know how that one feels! Best wishes to Jack and a speedy recovery. However, one FWA talent has decided to take advantage of the unfortunate event, Paul travell has insisted that he be the one to take on Iceman on Sunday 17th. So the turn of events could be very interesting for FWA fans. 1PW are continuing their American wet dream with no turning back, continuing to use the American talent on British soil approach. Hell I can't blame em, it makes money, because I cannot see anyone paying �80 to see any British talent right now! There is rumour though that 1PW are going to fund smaller British talent shows, with the effect of promoting UK Talent up to the standard of their big shows. It is a big undertaking, as unfortunately, the UK seems to be glitzed by the TV boys. Unfortunately so does 1PW, so I doubt we will see 1PW being the bastion of British wrestling it promised to be. They are giving a certain element of fans what they want so they are succeeding in a way though and it is very hard to criticise success. Speaking to Mitchell, as you may have noticed, we are trying to involve you, the UKScene fan in our reporting. No, we're not trying to get you to do the work, what we are trying to do is to get coverage of all the UKScene shows and you can help your favorite fed by submitting match reports to either Mitch, myself or even Kam. If you are a federation we can help you if you help us, make sure you email your shows and news directly to Mitchell or myself, also make sure that you give the lovely Devilish Angel a buzz and she will enter your shows onto the news round up. On a personal note, I'm beginning to notice that a lot of companies have been criticised in the past for having ambition. If you are a UK based promotion then we are on your side! Don't be scared to tell us what you want the country to know. [Mitchell@wretling101.com] [Saracen@wrestling101.com] [DA@wrestling101.com] Both Mitchell and I give priority to news items sent to our inboxes. LPW: The New Breed Added To April 15th ShowBy Devilish Angel - 04/10/2006 4:08 PM WWE: Survivor Series Matches Announced From Tomorrow & TJ WilsonBy Devilish Angel - 11/06/2006 2:25 PM Upcoming WAW Show DetailsBy Goldy - 06/10/2004 2:51 PM FWA Morecambe News Update By Goldy - 09/02/2004 4:05 PM FCW Update & Full Card For "Walsall Town Brawl" 18/03/05By Goldy - 03/15/2005 11:16 PM Results for ASW - Aylesbury - 14/03/05By Goldy - 03/14/2005 10:17 PM IWF v 3CW This Saturday, April 9th By Goldy - 04/06/2005 3:56 PM WAR Press ReleaseBy Goldy - 02/15/2005 1:39 PM BWA: First Matches Announced For August 11th ShowBy Devilish Angel - 07/25/2006 1:44 PM 3CW: Latest Card For November 10th ShowBy Devilish Angel - 10/30/2006 3:18 PM ST: I am back!By Saz - 05/27/2007 1:01 PMST: Wow...By Saz - 06/06/2007 10:23 PMOpinion and fact.By Saz - 12/09/2009 10:37 PMST: More wrestler ramblingsBy Saz - 07/22/2007 11:49 AMST: Time to get the attitude rightBy Saz - 09/22/2007 11:03 AMST: What does TV do for the UK Scene?By Saz - 11/27/2007 9:32 PMST: Viva l'Espania!By Saz - 08/18/2007 10:33 PMST: Yup, I got moreBy Saz - 06/19/2007 12:31 PMST: Do not talk to me about fakeBy Saz - 01/06/2008 1:17 PM
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package main import ( "github.com/stretchr/testify/assert" "testing" ) func TestConfig(t *testing.T) { assert.NotNil(t, args, "nil config args") assert.NotNil(t, args.Pub, "nil pub") assert.NotNil(t, args.Pub.URI, "nil uri") assert.True(t, len(args.Pub.URI) > 0, "no uris") assert.NotNil(t, args.Server, "nil server") assert.NotNil(t, args.Server.Host, "nil host") assert.NotEqual(t, args.Server.Port, 0, "nil Port") assert.NotNil(t, args.Server.Root, "nil root") assert.NotNil(t, args.Server.Token, "nil root") }
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As a busy mum you will be used to devoting lots of time to your family, but with the increasing cost of living, you may also want to find ways to generate some extra income at the same time. Nowadays, thanks to the internet, it's perfectly possible to find ways to earn money online which can be fitted around your busy family life. In today's competitive market, companies don't want to waste money on product development without knowing they are going to get a good return for their investment. To do this, they carry out market research into a whole host of different products and services, so by signing up to some of the online survey sites, you can make money by telling them what you think. Reputable sites such as SurveySavvy or Toluna South Africa are free to join, and you can then find out about available surveys either by signing in or via emails. You need to have a bit of patience for this, as it's quite common to get 'screened out' of survey if you don't fit the customer profile for that particular set of questions, but there is money to be made if you are persistent. Some sites focus on specific subjects. For example, the Brand Institute produces surveys about medical matters, so do a little research to find which sites work best for you. It may be that you are already skilled and qualified to offer services online. Accounting and bookkeeping are just two possible jobs that you can do with a good internet connection. Most businesses nowadays keep electronic records, and it's completely feasible to run an online accountancy business from home. Of course, this service may be less easy to fit around your existing commitments, as you might need to devote concentrated time to it, but it's perhaps possible if you know you can work at it once your children are in bed, or if you can share childcare with a partner to give you the time you need to complete jobs. This is something of a 'specialist' option, but if you are a keen photographer, and can take high quality photos, you could earn money by selling your photos to an online photo agency. It's important to use good equipment (a DSLR camera rather than an iPhone!) and you will need a good eye for an interesting photo opportunity, but sites such as iStockPhoto and Fotolia will pay for good images, and also offer useful advice about taking and preparing suitable photos to increase your chance of success. Parenting is a demanding and busy role, so why not make the most of your skills and knowledge by using the internet to target other parents? You could consider setting up an online business to sell baby items such as slings, clothing and toys. Sites such as PetitPoppet offer an online shop, but also have a local element, using a network of parents to offer support to others, such as giving advice about the best baby slings. By including blogs and forums, this kind of online site can develop into a thriving business. So, don't think that being at home with your family prevents you from earning money! Have the best of both worlds, by spending quality time with your children, whilst harnessing the internet to help you increase your spending power.
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After the careless, lame outing by the Super Eagles of Nigeria against South Africa's Bafana Bafana, the Matchday 24 encounter in the Nigeria Professional Football League (NPFL) gets the attention of football followers in the country. Hopefully, the action packed league encounters will make up for the weekend. The central talking point is the Abia Clasico, which is to hold on unaccustomed terrain, the UJ Esuene Stadium, Calabar. This will be the first time the both teams will trade their rivalry outside Abia State. The stakes are high for the clash between Enyimba FC and Abia Warriors, but the momentum it used to gather by way of fans trooping in to see the game will certainly drop. Consider that Nigerian fans have a poor travelling attitude, coupled with the fact Enyimba have been out of touch with their traditional home, Aba where a huge majority of their 'die-hard' fans reside. In Jos, league leaders are back home after playing on the road for two consecutive Matchdays. They host struggling Gombe United and this game might add to Manu Garba's woes considering the standing of his side on the long. For Gombe to get a positive result in Jos is as hard as winning the league title. FC in the previous game. Also on the radar of hot games to be served is the western derby involving MFM FC and relegation threatened Shooting Stars Sports Club. MFM FC's home record is not flawed so far. Their guests have been having bitter experiences in the league and there is a high probability that the Church Boys will give their visitors more reasons to be concerned in the top flight. The north is not left out of the party. There will be exciting times in Bauchi as Niger Tornadoes pay Wikki Tourists a visit. In katsina, the clash between Katsina United and El-Kanemi is worthy of note. El-Kanemi Warriors lost some surprise point in Maiduguri after their draw with defending champions, Rangers. Meanwhile, Sunshine Stars will travel to the Pyramid City without Austin Eguavoen who threw in the towel this week owing to series of poor performances. Kano Pillars got a draw, on the road, against Shooting Stars. This will serve as some morale booster as they host the Owena Waves. Tony Okpotu, still basking in the euphoria of his second hat trick of the season, will lead Loni Stars to Sagamu as the face bottom placed Remo Stars. The homers are not a "walk-over" side. In their previous game, in Umahia, they shared the spoils with Abia Warriors. Lobi Stars will have a tough date. Rivers United has been the shadow of themselves this term. At the beginning, they had some well-intentioned preparations, including a trip to Spain and an abroad coaching course for gaffer, Stanley Eguma. But all these have yet to materialize and put smiles on the faces of Port Harcourt fans. Quite awful on the road, not too convincing at home, the Port Harcourt based side have not lived up to the full potentials both in the individuals that make up the squad and the support from its financiers. This weekend, they host FC Ifeanyi Ubah who has been on a steady rise to the top. The visitors currently spot the second position and this is due to their good form both home and away. Rivers United needs the maximum point to consolidate their place in the domestic league, while they fight to stay put on the continent where they are still at the group stage. FC Ifeanyi Ubah who have since been ousting from the same competition on the continent have their full concentration on the domestic scene. One thing is sure; Rivers United will face a good squad in Yaw Preko's lads. They might likely drop points.
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Interior decoration and design have become increasingly popular in today's culture based on the success of shows such as Trading Spaces. Trading Spaces employs a handful of designers to decorate the houses of show guests. The guests are typically neighbors, but quite often friends and family as well. They "trade spaces" for a weekend, and each team works with a different designer on the other team's room. A budget is set as is a time limit, and after a grueling weekend of painting, sewing, and building, each team is surprised with a completely renovated room. If you are thinking about becoming an interior decorator, read on -- below are ten steps for you to consider when pursuing the interior decorating career. Spatial composition means using the available space in order to create the desired environment and convey the mood that the owner or builders picture. It is important for designers to know the space they are designing and to incorporate the size and proportionality into the design of the space. If a room is large, and the owner desires a look of power, then an interior designer would want to use items that enhance the size of the ceiling, floor, and room. There are several professional organizations for design and decoration in the United States. Becoming a member of one or more of these professional organizations is a great way for interior designers to stay informed about the latest in the interior design industry, network with other interior designers across the country, and learn about services and events for interior design professionals. See the list of professional organizations below. The main difference between an interior designer and an interior decorator is that a designer is required to possess a broader range of skills than an interior decorator does. As a result, an Interior Designer has more earnings potential than an interior decorator. While a decorator may focus purely on the aesthetics, an interior designer works to improve the function and safety of a space. A career in design thus entails a combination of engineering and art. Becoming an interior designer requires a lot more than knowing how to place furniture in a room. Coursework to receive an associate or bachelor's degree in interior design includes classes that teach technical skills, presentation techniques, technical understanding, history of style, materials and finishes, the design process, business procedures and administration, and contextual studies.
{ "redpajama_set_name": "RedPajamaC4" }
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/* * To change this license header, choose License Headers in Project Properties. * To change this template file, choose Tools | Templates * and open the template in the editor. */ package Datos; import java.sql.Connection; import java.sql.PreparedStatement; import java.sql.ResultSet; import java.sql.Statement; import java.text.SimpleDateFormat; import java.util.Calendar; import java.util.Date; import javax.swing.JOptionPane; import Datos.Socio; import java.awt.HeadlessException; import java.sql.SQLException; import java.util.ArrayList; import java.util.logging.Level; import java.util.logging.Logger; /** * * @author Bruno Matias */ public class Resolucion { private int id_resolucion; private String numero_resolucion; private String tipo; private String estado; private String descripcion_solicitud; private String descripcion_resolucion; private String fecha; private int id_socio; private String legajo_socio; private String ruta; private Statement sentencia; private ResultSet rsDatos; private Connection connection;//para la Conexion private PreparedStatement preparedStatement;//para preparar las querys private ResultSet resultSet; /** * @return the id_resolucion */ public int getId_resolucion() { return id_resolucion; } /** * @return the numero_resolucion */ public String getNumero_resolucion() { return numero_resolucion; } /** * @param numero_resolucion the numero_resolucion to set */ public void setNumero_resolucion(String numero_resolucion) { this.numero_resolucion = numero_resolucion; } /** * @return the tipo */ public String getTipo() { return tipo; } /** * @param tipo the tipo to set */ public void setTipo(String tipo) { this.tipo = tipo; } /** * @return the estado */ public String getEstado() { return estado; } /** * @param estado the estado to set */ public void setEstado(String estado) { this.estado = estado; } /** * @return the descripcion_solicitud */ public String getDescripcion_solicitud() { return descripcion_solicitud; } /** * @param descripcion_solicitud the descripcion_solicitud to set */ public void setDescripcion_solicitud(String descripcion_solicitud) { this.descripcion_solicitud = descripcion_solicitud; } /** * @return the legajo_socio */ /** * @param legajo_socio the legajo_socio to set * * * / ** * @param tipoEstado * * @param socioX */ public Resolucion GenerarResolucion(Socio socioX, int tipoEstado) { //Tipo de Resolucion que puede tener el socio // Matriculacion // suspendido // 1 = activo // 2 = suspendido Resolucion re = new Resolucion(); try { setConnection(Conexion.Cadena()); int id_Socio = socioX.getId_socio(); String leg = socioX.getLegajo_socio(); String Estado = "Aceptada"; String descripcionR = "Fue Aceptada"; String descripcionS = ""; String tipoRes = ""; Date fechaActual = new Date(); SimpleDateFormat formatoFecha = new SimpleDateFormat("yyyy-MM-dd"); String fechaResolucion = formatoFecha.format(fechaActual); Calendar fecha = Calendar.getInstance(); int año = fecha.get(Calendar.YEAR); System.out.println(año); String nResolucion = id_Socio + "/" + año; preparedStatement = connection.prepareStatement("INSERT INTO resoluciones (numero_resolucion,tipo,estado,descripcion_Solicitud ,descripcion_resolucion,fecha_resolucion,legajo_socio,id_socio) VALUES (?, ? , ? , ?, ?,?,?,?)"); preparedStatement.setString(1, nResolucion); // preparedStatement.setString(2, "Matriculacion"); switch (tipoEstado) { case 1: tipoRes = "matriculacion"; descripcionS = "La solicitud es de Matriculacion0"; preparedStatement.setString(2, tipoRes); preparedStatement.setString(4, descripcionS); break; case 2: tipoRes = "suspension"; descripcionS = "La solicitud es de Suspension"; preparedStatement.setString(2, tipoRes); preparedStatement.setString(4, descripcionS); break; } // Fin Switch preparedStatement.setString(3, Estado); preparedStatement.setString(5, descripcionR); preparedStatement.setString(6, fechaResolucion); preparedStatement.setString(7, leg); preparedStatement.setInt(8, id_Socio); int res = getPreparedStatement().executeUpdate(); if (res > 0) { JOptionPane.showMessageDialog(null, "Resolucion Guardada"); //System.out.println("Hola entre Si"); //CAMBIAR ESTADO DEL SOCIO AFUERA DE ESTE METODO, PUEDE SER ANTES //Socio cambioE = new Socio(); //cambioE.cambiarEstado(socioX, 2); re.setNumero_resolucion(nResolucion); re.setTipo(tipoRes); re.setEstado(Estado); re.setDescripcion_solicitud(descripcionS); re.setDescripcion_resolucion(descripcionR); re.setFecha(fechaResolucion); re.setLegajo_socio(leg); re.setId_socio(id_Socio); } else { JOptionPane.showMessageDialog(null, "Error al Guardar Resolucion"); System.out.println("Hola entre NO"); } getConnection().close(); } catch (ClassNotFoundException | SQLException | HeadlessException e) { boolean ex; } return re;//devuelve resolucio sin ID } // fin de generar Resolcuion public void guardarRutaArchivo(int id_res, String ruta) throws ClassNotFoundException, SQLException{ try { connection = Conexion.Cadena(); System.out.println("ID RES: "+id_res); System.out.println("Ruta: "+ruta); preparedStatement = connection.prepareStatement("UPDATE resoluciones SET ruta = ? WHERE id_resolucion=?"); preparedStatement.setString(1, ruta); preparedStatement.setInt(2, id_res); int resp = preparedStatement.executeUpdate(); if (resp > 0) { //System.out.println("Nuevo Estado: "+socioX.getEstado()+"\n"); System.out.println("Resolucion Actualizado"); //JOptionPane.showMessageDialog(null, "Socio Actualizado: "+socioX.getId_socio()); //LimpiarCajas(); } else { System.out.println("Error\n"); //JOptionPane.showMessageDialog(null, "Error al Actualizar Socio"); //LimpiarCajas(); } connection.close(); } catch (Exception e) { } } public Resolucion BuscarX(String num_res) throws ClassNotFoundException { Resolucion nuevaRes=new Resolucion(); try { Connection cn = Conexion.Cadena(); String SQL = "SELECT * FROM resoluciones"+ " WHERE numero_resolucion ='"+num_res+"' "; sentencia=cn.createStatement(ResultSet.TYPE_SCROLL_SENSITIVE, ResultSet.CONCUR_READ_ONLY); rsDatos = sentencia.executeQuery(SQL); String num,tipo,estado,descrip_solic,descrip_res,fecha,leg_socio, ruta; int id_res,id_socio; if(rsDatos.first()){ id_res=rsDatos.getInt("id_resolucion"); id_socio=rsDatos.getInt("id_socio"); num=rsDatos.getString("numero_resolucion"); tipo=rsDatos.getString("tipo"); estado=rsDatos.getString("estado"); descrip_solic=rsDatos.getString("descripcion_solicitud"); descrip_res=rsDatos.getString("descripcion_resolucion"); leg_socio=rsDatos.getString("legajo_socio"); ruta=rsDatos.getString("ruta"); SimpleDateFormat formatoFecha = new SimpleDateFormat("yyyy-MM-dd"); fecha = formatoFecha.format(rsDatos.getDate("fecha_resolucion")); // System.out.println(nom); // System.out.println(ape); // System.out.println(categ); // System.out.println(leg); // System.out.println(tel); nuevaRes.setId_resolucion(id_res); nuevaRes.setId_socio(id_socio); nuevaRes.setNumero_resolucion(num); nuevaRes.setTipo(tipo); nuevaRes.setEstado(estado); nuevaRes.setDescripcion_solicitud(descrip_solic); nuevaRes.setDescripcion_resolucion(descrip_res); nuevaRes.setFecha(fecha); nuevaRes.setLegajo_socio(leg_socio); nuevaRes.setRuta(ruta); }else{ System.out.println("es nulo"); } } catch (SQLException ex) { System.out.println("No Correcto"); Logger.getLogger(Socio.class.getName()).log(Level.SEVERE, null, ex); } return nuevaRes; } public ArrayList<Resolucion> listar(){ ArrayList listaResoluciones = new ArrayList(); Resolucion res; try { Connection cn = Conexion.Cadena(); String SQL = "SELECT * FROM resoluciones"; sentencia=cn.createStatement(ResultSet.TYPE_SCROLL_SENSITIVE, ResultSet.CONCUR_READ_ONLY); rsDatos = sentencia.executeQuery(SQL); //System.out.println("Correcto"); while (rsDatos.next()) { res = new Resolucion(); res.setNumero_resolucion(rsDatos.getString(2)); res.setTipo(rsDatos.getString(3)); res.setEstado(rsDatos.getString(4)); res.setFecha(rsDatos.getString(7)); res.setLegajo_socio(rsDatos.getString(8)); res.setRuta(rsDatos.getString(9)); listaResoluciones.add(res); } } catch (Exception e) { } return listaResoluciones; } /** * @return the id_socio */ public int getId_socio() { return id_socio; } /** * @return the sentencia */ public Statement getSentencia() { return sentencia; } /** * @param sentencia the sentencia to set */ public void setSentencia(Statement sentencia) { this.sentencia = sentencia; } /** * @return the rsDatos */ public ResultSet getRsDatos() { return rsDatos; } /** * @param rsDatos the rsDatos to set */ public void setRsDatos(ResultSet rsDatos) { this.rsDatos = rsDatos; } /** * @return the connection */ public Connection getConnection() { return connection; } /** * @param connection the connection to set */ public void setConnection(Connection connection) { this.connection = connection; } /** * @return the preparedStatement */ public PreparedStatement getPreparedStatement() { return preparedStatement; } /** * @param preparedStatement the preparedStatement to set */ public void setPreparedStatement(PreparedStatement preparedStatement) { this.preparedStatement = preparedStatement; } /** * @return the resultSet */ public ResultSet getResultSet() { return resultSet; } /** * @param resultSet the resultSet to set */ public void setResultSet(ResultSet resultSet) { this.resultSet = resultSet; } /** * @return the legajo_socio */ public String getLegajo_socio() { return legajo_socio; } /** * @return the descripcion_resolucion */ public String getDescripcion_resolucion() { return descripcion_resolucion; } /** * @param descripcion_resolucion the descripcion_resolucion to set */ public void setDescripcion_resolucion(String descripcion_resolucion) { this.descripcion_resolucion = descripcion_resolucion; } /** * @return the fecha */ public String getFecha() { return fecha; } /** * @param fecha the fecha to set */ public void setFecha(String fecha) { this.fecha = fecha; } /** * @param id_socio the id_socio to set */ public void setId_socio(int id_socio) { this.id_socio = id_socio; } /** * @param legajo_socio the legajo_socio to set */ public void setLegajo_socio(String legajo_socio) { this.legajo_socio = legajo_socio; } /** * @return the ruta */ public String getRuta() { return ruta; } /** * @param ruta the ruta to set */ public void setRuta(String ruta) { this.ruta = ruta; } /** * @param id_resolucion the id_resolucion to set */ public void setId_resolucion(int id_resolucion) { this.id_resolucion = id_resolucion; } } // Fin de CLASS RESOLCUION
{ "redpajama_set_name": "RedPajamaGithub" }
31,809
The syntax used to add a foreign key constraint to a table. Get the name of the database type appropriate for casting operations (via the CAST() SQL function) for the given Types typecode. Get the string to append to SELECT statements to acquire WRITE locks for this dialect. Is this dialect known to support what ANSI-SQL terms "row value constructor" syntax; sometimes called tuple syntax. Does this dialect support referencing the table being mutated in a subquery. constraintName - The FK constraint name. primaryKey - The explicit columns in the referencedTable referenced by this FK. Basically, does it support syntax like "... where (FIRST_NAME, LAST_NAME) = ('Steve', 'Ebersole') ...". True if this SQL dialect is known to support "row value constructor" syntax; false otherwise. Get the string to append to SELECT statements to acquire WRITE locks for this dialect. Location of the of the returned string is treated the same as getForUpdateString. timeout - in milliseconds, -1 for indefinite wait and 0 for no wait. The appropriate LOCK clause string. Does this dialect support referencing the table being mutated in a subquery. The "table being mutated" is the table referenced in an UPDATE or a DELETE query. And so can that table then be referenced in a subquery of said UPDATE/DELETE query. True if this dialect allows references the mutating table from a subquery.
{ "redpajama_set_name": "RedPajamaC4" }
44,646
TidyHQ Terms of Service TidyHQ ABN 88 609 879 601 1.1 TidyHQ is a comprehensive software solution for the management of clubs, associations, businesses any other organisations. TidyHQ is proudly Australian owned and developed. In general, TidyHQ wants to have as many happy Customers as possible. We would be remiss to change pricing, features or services in a way that made Customer's unhappy. However, as a SaaS product, TidyHQ will change over time (for the better, of course). 1.2 In these Terms of Service, the "Important Terms" mostly deal using TidyHQ, and the "General Conditions" set out the legal basis on which TidyHQ is provided. You must accept these terms to use TidyHQ. 1.3 TidyHQ treats the confidentiality of our Customer's information seriously, and handles all personal information in accordance with Australian privacy laws. Simply, we protect our Customers' information, not exploit it. IMPORTANT TERMS A KEY TERMS A.1 The following terms are used regularly throughout these Terms of Service and have a particular meaning: (a) Account means a registered TidyHQ account. (b) Agreement means the agreement formed in accordance with these Terms of Service between the Company and the User. (c) Application means the TidyHQ SaaS application accessible via login through the Site. (d) API means the TidyHQ application programming interface. (e) Authorised User means a User that has been granted access to another User's Account by the owner of that Account. (f) Company means TidyHQ Pty Ltd ABN 88 609 879 601. (g) Customer means the person that TidyHQ is licensed to under this Agreement (which if in doubt shall be the named Account holder). (h) Event means an event created by a Customer within TidyHQ, for which a fee may be payable by a Member. (i) Fee means any fees payable to the Company for access to, or use of TidyHQ. (j) Free Account means a Customer Account for which no Fees are payable. (k) Member means a registered user of TidyHQ that is not a Customer. (l) Membership means registration as a member of an Organisation via TidyHQ. (m) Organisation means a club, association, business or any other type of organisation that is managed by a Customer using TidyHQ. (n) Privacy Policy means the Company's privacy policy as updated from time-to-time, accessible from here: http://www.tidyhq.com/privacy (o) Site means the website found at http://www.TidyHQ.com (p) Services means the services provided by the Company via TidyHQ. (q) Subscription Fee means the fee charged for access to the Application. (r) Third Party Services means any of the Customer's third party service account connected to and/or integrated with TidyHQ. (s) TidyHQ means the Company's suite of tools, applications and services, known together as "TidyHQ", licensed to a User under this Agreement. (t) User means either or both of a Customer and a Member, as the use of the term in its context implies. (u) User Data means all information, records, data, code, documents and other such materials that the User either owns or is authorised to make available for use via TidyHQ. (v) Visitor means a visitor to a TidyHQ webpage that does not require an Account to view. B AGREEMENT B.1 The licence granted under this Agreement shall be ongoing until terminated in accordance with the terms of this Agreement. B.2 The User agrees to use TidyHQ in accordance with the terms of this Agreement. C PAYING FOR TIDYHQ C.1 Fees (a) Fees apply as advertised to the use of TidyHQ, and the terms of those Fees are set out in the General Conditions. (b) The Company may charge a Fee on any transaction between Users of TidyHQ. C.2 Currency. All Fees are quoted in Australian dollars, however transactions may be processed in an equivalent foreign currency (such as US dollars or British pounds). C.3 GST. For Customers in Australia, GST is applicable to any Fees charged by the Company to the User. Unless expressed otherwise, all Fees shall be deemed inclusive of GST. The Company will provide the Customer with a Tax Invoice for any payments. C.4 Refunds. No refunds of Fees are offered other than as required by law. C.5 Late Payment. (a) If the Customer does not pay the full Subscription Fees as required, the Company may suspend all User access to TidyHQ for that Account. (b) If Subscription Fees are not brought out of arrears within 28 days of becoming overdue, the Company may terminate the Customer's Account in TidyHQ without notice and end this Agreement. (c) The User agrees that the Company shall not be responsible or liable in any way for: i Interruptions to the availability of TidyHQ in the event of (a); ii Loss of User Data in the event of (b). D USING TIDYHQ D.1 To access TidyHQ, each User must register with TidyHQ (either as a Customer or as a Member, as the case may be) with a valid email address. D.2 The Company provides instructional documentation on the Site and within TidyHQ to assist Users with TidyHQ. This documentation shall be updated from time-to-time. D.3 The perquisites to use TidyHQ are: (a) Access to the Application; an (b) An internet connection. D.4 Application (a) The Application is accessible to registered Users via login from the Site. To use TidyHQ, it is necessary that the User has access to the Application. (b) The Application: i Contains the User Data that the User enters into the Application; ii Connects the User's Account with Third Party Services; and iii Provides the User with Account management. D.5 Third Party Services (a) TidyHQ connects to and integrates with many Third Party Services. (b) TidyHQ cannot warrant the ongoing availability or efficacy of any Third Party Services. (c) The User authorises the Company to access the User Data in any Third Party Services enabled by the User. (d) The User must comply with the terms of use of any Third Party Service, and in no way will the Company be liable for any breach of such terms by the User's connection of TidyHQ to a Third Party Service. D.6 Dependencies (a) The User agrees and acknowledges that: i TidyHQ has third party dependencies which may affect its availability, including (without limitation) infrastructure providers; and ii The Company has no means of controlling the availability of such dependencies, although each of those services has a robust operating standard suitable for commercial dependency. D.7 Use of API (a) TidyHQ may provide access to the API for a Fee. (b) In addition to this Agreement, A User's use of the API will be subject to the TidyHQ API Terms of Service. D.8 Financial Matters (a) While the Company endeavours to make TidyHQ as user-friendly, reliable and accurate as possible, a User that makes or receives payment, or uses financial features of TidyHQ does so at their own risk. To the extent permitted by law the Company accepts no responsibility for: i Fees charged by a Customer in relation to a Membership or Event; or ii The accuracy of a financial information generated by TidyHQ. D.9 Support (a) The Company provides user support for TidyHQ via a dedicated support email. (b) The Company shall endeavour to respond to all support requests within 24 hours. (c) The Company reserves the right to require the payment of reasonable Fees for non-standard support requests prior to the provision of such support. E ACCOUNT ACCESS USING THIRD PARTY SERVICES E.1 Registration & Login (a) A User may be able to register for the Application, and access the Services, by using an account with certain Third Party Services (including, but not limited to, Facebook); (b) As part of the functionality of the Application a User may connect their profile with a Third Party Service by: i Providing the User's Third Party Service login information to the Company through the Application; or ii Allowing the Company to access the User's Third Party Service in accordance with its terms & conditions of service; and (c) When connecting to the Application using a Third Party Service the User warrant that they are not in breach any of the Third Party Service' terms & conditions of service. E.2 Ongoing Availability (a) The User agrees that access to the Application may be unavailable if the Third Party Service becomes unavailable, and that the User may lose functionality or content that is shared between the Third Party Service and the Application; (b) The User may disconnect the connection between the Application and the Third Party Service at any time. (c) The Company has no relationship with any Third Party Service and cannot guarantee the efficacy of any Third Party Service connection. E.3 Data from Third Party Services Where a User connects and/or registers their profile using a Third Party Service, the User authorises the Company to use data from that Third Party Service to create the User's profile on the Application. F CUSTOMER TERMS F.1 The Customer warrants that it is a natural person authorised to create an account to establish, maintain and pay for the Customer Account on behalf of each Organisation. F.2 The Customer shall be responsible to the Company for: (a) Each Organisation that it manages using the Customer's account; (b) The accuracy of the information it makes available via the Application; (c) Each Authorised User to whom the Customer provides access to the Customer's account. F.3 Assignment of Account (a) In the event that the Customer ceases to be authorised by an Organisation, and the Organisation has given authority to another individual, or simply wishes to transfer the Customer account to another individual (Delegate) to operate a Customer account, then the Customer must arrange with the Company to assign the Customer Account to the Delegate. (b) The procedure that must be followed in order to effect an assignment of a Customer account shall be as detailed on the Company's Website from time-to-time, or within TidyHQ. In default the Customer must contact the Company to request an assignment of a Customer account. (c) The Customer will not be released of its obligations under this Agreement, and an assignment to the Delegate will not be affected until: i The Delegate has supplied such information as is required by the Company to create a Customer Account; ii The Delegate has accepted these Terms of Service; and iii The Company is satisfied (in its absolute discretion) that the Delegate has the authority to act on behalf of the Organisation, and is competent to assume all the responsibilities of a Customer subject to this Agreement. F.4 Connecting Organisations (a) Organisations subject to separate Customer accounts may be linked with other Organisations within TidyHQ provided that: i One of the Organisations is designated as the parent Organisation (Parent) and the other Organisation is designated as the subordinate Organisation (Child); ii Each Customer consents to link their Organisation with the other; iii Each Customer indemnifies the Company from any negative consequences of linking the Organisations. Any dispute that arises between Customers holding linked accounts shall be dealt with strictly between themselves. (b) The Customer that holds each linked Organisation may set the administrative privileges and features that the other Customer may access. F.5 Termination of Customer Account The Customer may terminate this Agreement by written notice and cease using TidyHQ. No pro-rata refunds are offered for terminated accounts. The Company may terminate this Agreement on no less than 14 days' written notice to the Customer, and access shall terminate at the end of the Customer's billing cycle active at the expiry of that notice period (if applicable). G MEMBER TERMS G.1 Registration. (a) A Member must register as a Member to access the Application; and (b) Until registration as a Member is confirmed by the Company a license to access the Application will not be granted. G.2 Verification The Member may be required to verify their identity by (without limitation) email, telephone, residential or business address, social media, referrals, references and/or formal photographic identification. A Member must provide the Company with all necessary verifications the Company requires in order to provide access to the Application. G.3 Termination of Member Account Either the Company or the Member may end this Agreement at any time by written notice to the other in accordance with these Terms. H VISITOR TERMS H.1 Except where specifically stated to the contrary, the Company makes no representations as to the accuracy of any information contained in a webpage generated by a Customer via TidyHQ. H.2 In no circumstance will the Company be liable to a Visitor for its use of, or access to the Site. I SPECIAL CONDITIONS I.1 The parties may agree to any Special Conditions to this Agreement in writing. Where the parties make such Special Conditions those Special Conditions shall prevail over any inconsistency with any other provisions of this Agreement. ‍1 INTERPRETATION 1.1 The following definitions apply in this document: (a) ABN means Australian Business Number. (b) ACN means Australian Company Number. (c) Business Day means a day (other than a Saturday, Sunday or public holiday) on which banks are open for general banking business in Melbourne, Australia. (d) Commencement Date means the date set out in this Agreement. (e) Confidential Information means all information (whether or not it is described as confidential) in any form or medium concerning any past, present or future business, operations or affairs of either party, including, without limitation: i all technical or non-technical data, formulae, patterns, programs, devices, methods, techniques, plans, drawings, models and processes, source and object code, software and computer records; ii all business and marketing plans and projections, details of agreements and arrangements with third parties, and User and supplier information and lists; iii all financial information, pricing schedules and structures, product margins, remuneration details and investment outlays; iv all information concerning any employee, customer, contractor, supplier or agent of the relevant party; v the party's policies and procedures; and vi all information contained in this document, but excludes information that the other party can establish: vii Is known by or is in the other party's possession or control other than through a breach of this document and is not subject to any obligation of confidence; or viii Is in the public domain other than by a breach of this document or any obligations of confidence. (f) Corporations Act means the Corporations Act 2001 (Cth). (g) Force Majeure means an event or cause beyond the reasonable control of the party claiming force majeure. It includes each of the following, to the extent it is beyond the reasonable control of that party: i Act of God, lightning, storm, flood, fire, earthquake or explosion cyclone, tidal wave, landslide, adverse weather conditions; ii Act of public enemy, war (declared or undeclared), terrorism, sabotage, blockade, revolution, riot, insurrection, civil commotion, epidemic; iii The effect of any change in applicable laws, orders, rules or regulations of any government or other competent authority; and iv Embargo, inability to obtain necessary materials, equipment or facilities, or power or water shortage. (h) General Conditions means the terms and conditions set out in the section of this Agreement entitled "General Conditions". (i) GST has the meaning given by the A New Tax System (Goods and Services Tax) Act 1999 (Cth). (j) Intellectual Property means all copyright, patents, inventions, trade secrets, know-how, product formulations, designs, circuit layouts, databases, registered or unregistered trademarks, brand names, business names, domain names and other forms of intellectual property; (k) Intellectual Property Rights means, for the duration of the rights in any part of the world, any Moral Rights, industrial or intellectual property rights, whether registrable or not, including in respect of Intellectual Property, applications for the registration of any Intellectual Property and any improvements, enhancements or modifications to any Intellectual Property registrations. (l) Moral Rights means: i Moral rights pursuant to the Copyright Act 1968 (Cth); ii Or any rights analogous to the rights set out in Article 6bis of the Berne Convention for Protection of Literary and Artistic Works 1886 (as amended from time to time). (m) Important Terms means this Agreement's details and variables set out in the section of this Agreement entitled "Important Terms". (n) Privacy Act means the Privacy Act 1989 (Cth). (o) Special Conditions means the terms and conditions set out in the section of this agreement entitled "Special Conditions". (p) Tax Invoice has the meaning given by the A New Tax System (Goods and Services Tax) Act 1999 (Cth). 1.2 Headings are only for convenience and do not affect interpretation. The following rules apply unless the context requires otherwise: (a) The singular includes the plural and the opposite also applies. (a) If a word or phrase is defined, any other grammatical form of that word or phrase has a corresponding meaning. (b) A reference to a clause refers to clauses in this Agreement. (c) A reference to legislation is to that legislation as amended, re enacted or replaced, and includes any subordinate legislation issued under it. (d) Mentioning anything after includes, including, or similar expressions, does not limit anything else that might be included. (e) A reference to a party to this Agreement or another agreement or document includes that party's successors and permitted substitutes and assigns (and, where applicable, the party's legal personal representatives). (f) A reference to a person, corporation, trust, partnership, unincorporated body or other entity includes any of them. (g) A reference to information is to information of any kind in any form or medium, whether formal or informal, written or unwritten, for example, computer software or programs, concepts, data, drawings, ideas, knowledge, procedures, source codes or object codes, technology or trade secrets. (h) A reference to dollars or $ is to an amount in Australian currency. 2 APPLICATION OF THIS AGREEMENT 2.1 This Agreement applies to use of and access to TidyHQ. 2.2 Where the User does not accept, or can no longer comply with the terms and conditions of this Agreement, the User must immediately cease using TidyHQ. 2.3 This Agreement may be updated by the Company at its absolute discretion from time-to-time, and unless stated otherwise by the Company in writing, such updates shall come into effect for use of TidyHQ at the commencement of the User's next billing period. 3 SOLUTION 3.1 The User agrees and accepts that TidyHQ is: (a) Hosted by the Company using a secure third-party hosting service and shall only be installed, accessed and maintained by the Company; (b) Accessed by the User using the internet or other connection to the servers hosting the TidyHQ and is not available 'locally' from the User's systems; and (c) Managed and supported exclusively by the Company from the Company's third party hosting service and that no 'back-end' access to TidyHQ is available to the User unless expressly agreed in writing. 3.2 As a hosted and managed service, the Company reserves the right to upgrade, maintain, tune, backup, amend, add or remove features, redesign, improve or otherwise alter TidyHQ. 3.3 The Company shall not exercise its rights under clause 3.2 in a manner that would intentionally cause the User to lose access to User Data or fundamentally decrease the utility of TidyHQ to the User, other than in accordance with the terms of this Agreement. 4 LICENSE 4.1 By accepting the terms and conditions of this Agreement, the User is granted a limited, non-exclusive and revocable license to access and use TidyHQ for the duration of this Agreement, in accordance with the terms and conditions of this Agreement. 4.2 The Company may revoke or suspend the User's license(s) in its absolute discretion for any reason that it sees fit, including for breach of the terms and conditions in this Agreement by the User or any of its users. The Company will ordinarily advise the User of any suspension or revocation however it is under no obligation to do so. 5 USE 5.1 The User agrees that it shall only use TidyHQ for legal purposes and shall not use it to engage any conduct that is unlawful, immoral, threatening, abusive or in a way that is deemed unreasonable by the Company in its discretion. 6 AUTHORISED USERS 6.1 The Customer shall authorise users to access TidyHQ in its absolute discretion. The Customer agrees that additional Fees may be payable for each additional user it authorises. 6.2 The Company accepts no liability for access to User Data by users authorised by the User or using login details of users authorised by the User. 6.3 The User is solely responsible for the security of its username and password for access to TidyHQ. 6.4 The User is responsible for ensuring that users comply with this Agreement in full and are liable for any breach of them. 7 USER DATA 7.1 The Company obtains no right, title or interest in User Data including any Intellectual Property found within it. 7.2 The Company accepts no liability for the content of User Data. 7.3 The User is responsible for the accuracy, quality and legality of User Data and the User's acquisition of it, and the users that create, access and/or use User Data. 7.4 Despite clause 7.1, the Company shall be authorised to permanently delete User Data where outstanding Fees remain unpaid in accordance the Important Terms. 7.5 The Company shall not access, use, modify or otherwise deal with User Data except where required by compulsion of law or upon the User's authority (such as to provide support for TidyHQ). 8 PRIVACY 8.1 The Company maintains the Privacy Policy in compliance with the provisions of the Privacy Act for data that it collects about the User and other customers. 8.2 The Privacy Policy does not apply to how the User handles User Data. It is the User's responsibility to meet the obligations of the Privacy Act by implementing a Privacy Policy in accordance with law. 8.3 The Company makes no warranty as to the suitability of TidyHQ in regards to the User's privacy obligations at law or contract, and it is the User's responsibility to determine whether TidyHQ is appropriate for the User's circumstances. 9 INVOICING & PAYMENTS 9.1 The Company shall issue the User a Tax Invoice for all Fees for which GST applies. 9.2 The terms of payment set out in the Important Terms shall apply. 9.3 Should the User dispute a Tax Invoice, the User must notify the Company of the disputed item within 5 Business Days of the date of the Tax Invoice. The User must pay the amount of the Tax Invoice not in dispute within the prescribed payment period. 9.4 Overdue Tax Invoices shall accrue interest at the rate of 1.5% per month, or in default, the maximum rate of penalty interest prescribed under law. 10 DATA 10.1 Security. The Company takes the security of TidyHQ and the privacy of its Users very seriously. The User agrees that the User shall not do anything to prejudice the security or privacy of the Company's systems or the information on them. 10.2 Transmission. The Company shall do all things reasonable to ensure that the transmission of data occurs according to accepted industry standards. It is up to the User to ensure that any transmission standards meet the User's operating and legal requirements. 10.3 Storage. The Company may limit the amount of data that the User stores in TidyHQ, and shall advise the User of such. Data that is stored with the Company shall be stored according to accepted industry standards. 10.4 Backup. The Company shall perform backups of its entire systems in as reasonable manner at such times and intervals as is reasonable for its business purposes. The Company does not warrant that it is able to backup or recover specific User Data from any period of time unless so stated in writing by the Company. 11 ACCESS 11.1 Solution. By accepting the terms of this Agreement the User agrees that the Company shall provide access to TidyHQ to the best of its abilities, however it accepts no responsibility for ongoing access to TidyHQ. 12 INTELLECTUAL PROPERTY 12.1 Trademarks. The Company has moral & registered rights in its trademarks and the User shall not copy, alter, use or otherwise deal in the marks without the prior written consent of the Company. 12.2 Proprietary Information. TidyHQ may use software and other proprietary systems and Intellectual Property for which the Company has appropriate authority to use, and the User agrees that such is protected by copyright, trademarks, patents, proprietary rights and other laws, both domestically and internationally. The User warrants that it shall not infringe on any third-party rights through the use of TidyHQ. 12.3 Solution. The User agrees and accepts that TidyHQ is the Intellectual Property of the Company and the User further warrants that by using TidyHQ the User will not: (a) Copy TidyHQ or the services that it provides for the User's own commercial purposes; and (b) Directly or indirectly copy, recreate, decompile, reverse engineer or otherwise obtain, modify or use any source or object code, architecture, algorithms contained in TidyHQ or any documentation associated with it. 12.4 Content. All content (with the exception of User Data) remains the Intellectual Property of the Company, including (without limitation) any source code, ideas, enhancements, feature requests, suggestions or other information provided by the User or any other party with respect to TidyHQ. 13 CONFIDENTIALITY 13.1 The Company agrees to keep all User Data in the strictest confidence, and to the extent User Data is accessed and/or received by TidyHQ it shall be deemed as Confidential Information for the purposes of this Agreement. 13.2 Each party acknowledges and agrees that: (a) The Confidential Information is secret, confidential and valuable to the disclosing party (Discloser); (b) To owes an obligation of confidence to the Discloser concerning the Confidential Information; (c) It must not disclose the Confidential Information to a third party except as permitted in this Agreement; (d) All Intellectual Property rights remain vested in the Discloser but disclosure of Confidential Information does not in any way transfer or assign any rights or interests in the Intellectual Property to the receiving party; and (e) Any breach or threatened breach by the receiving party of an obligation under this Agreement may cause the Discloser immediate and irreparable harm for which damages alone may not be an adequate remedy. Consequently the Discloser has the right, in addition to other remedies available at law or in equity, to seek injunctive relief against the receiving party (and its agents, assigns, employees, officers and directors, personally) or to compel specific performance of this clause. 13.3 A party must notify the Discloser in writing, giving full details known to it immediately, when it becomes aware of: (a) Any actual, suspected, likely or threatened breach by it of any obligations it has in relation to the Confidential Information. (b) Any actual, suspected, likely or threatened breach by any person of any obligation in relation to the Confidential Information; or (c) Any actual, suspected, likely or threatened theft, loss, damage, or unauthorised access, use or disclosure of or to any Confidential Information. 13.4 The receiving party must promptly take all steps that the Discloser may reasonably require and must co-operate with any investigation, litigation or other action of the Discloser or of a related body corporate if there is: (a) Any actual, suspected, likely or threatened breach of a term of this Agreement; or (b) Any theft, loss, damage or unauthorised access, use or disclosure of or to any Confidential Information that is or was in its possession or control. 14 LIABILITY & INDEMNITY 14.1 The User agrees that it uses TidyHQ at its own risk. 14.2 The User acknowledges that the Company is not responsible for the conduct or activities of any user and that the Company is not liable for such under any circumstances. 14.3 The User agrees to indemnify the Company for any loss, damage, cost or expense that the Company may suffer or incur as a result of or in connection with the User's use of TidyHQ or conduct in connection with TidyHQ, including any breach by the User of this Agreement. 14.4 In no circumstances will the Company be liable for any direct, incidental, consequential or indirect damages, loss or corruption of data, loss of profits, goodwill, bargain or opportunity, loss of anticipated savings or any other similar or analogous loss resulting from the User's access to, or use of, or inability to use TidyHQ, whether based on warranty, contract, tort, negligence, in equity or any other legal theory, and whether or not the Company knew or should have known of the possibility of such damage, to business interruption of any type, whether in tort, contract or otherwise. 14.5 Certain rights and remedies may be available under the Competition and Consumer Act 2010 (Cth) or similar legislation of other States or Territories and may not be permitted to be excluded, restricted or modified. Apart from those that cannot be excluded, the Company and the Company's related entities exclude all conditions and warranties that may be implied by law. To the extent permitted by law, the Company's liability for breach of any implied warranty or condition that cannot be excluded is restricted, at the Company's option to: (a) The re-supply of services or payment of the cost of re-supply of services; or (b) The replacement or repair of goods or payment of the cost of replacement or repair. 15 BREACH 15.1 Where a party is in breach of this Agreement, the other party may issue a written notice (Breach Notice) requiring the party in breach that must set out: (a) The nature of the breach; (b) The provisions of the Agreement that are alleged to have been breached; (c) A reasonable timeframe to remedy the breach in no less than 10 Business Days; and (d) The action required to remedy the breach. 15.2 Where a party issues a compliant Breach Notice in accordance with clause 15.1, the receiving party shall be required to respond and/or remedy the breach as so set out in the Breach Notice. Failure to respond in writing setting out: (a) The steps taken to remedy the breach; or (b) Why the party believes it is not in breach as put forward in the Breach Notice, (c) Shall not in itself confirm the alleged breach but shall be in itself a breach of this Agreement. 15.3 Failure to remedy a breach set out in a Breach Notice shall be a material breach of this Agreement (Material Breach). 16 TERMINATION 16.1 Breach. Where a party is in Material Breach of this Agreement, the other party may terminate this Agreement by giving written notice of termination, which shall become effective 5 Business Days after the date of the notice. 16.2 Insolvency. Either party may terminate this Agreement immediately by notice, if either party: (a) Stops or suspends or threatens to stop or suspend payment of all or a class of its debts; (b) Is insolvent within the meaning of section 95A of the Corporations Act; (c) Fails to comply with a statutory demand (within the meaning of section 459F(1) of the Corporations Act) unless: (d) The debt to which the statutory demand relates is discharged within 15 Business Days of the date of the failure; or (e) The party demonstrates to the satisfaction of the other party (acting reasonably) that it is able to pay all its debts as and when they become due and payable; (f) Has an administrator appointed in respect of it; (g) Has a controller within the meaning of section 9 of the Corporations Act or similar officer appointed to the whole or a substantial part of its assets or undertaking and that controller or similar officer is not removed within 15 Business Days of the appointment; (h) Has an order made or a resolution passed for its winding up or dissolution or it enters into an arrangement, compromise or composition with or assignment for the benefit of its creditors or a class of them; (i) Has any security enforced over, or a distress, execution or other similar process levied or served against, the whole or a substantial part of its assets or undertaking; or (j) Is subject to any event, which, under the law of any relevant jurisdiction, has an analogous or equivalent effect to any of the events listed above. 16.3 Expiry or termination of this Agreement is without prejudice to and does not affect the accrued rights or remedies of any of the parties arising in any way out of this Agreement up to the date of expiry or termination. 16.4 The rights and obligations under the relevant provisions of clauses 6, 7, 8, 9, 12, 13, 14, 15, 16, 17, 18 and 19 survive termination of this Agreement. 17 DISPUTES 17.1 All disputes shall be handled in accordance with the Company's dispute resolution policy. 17.2 Where the Company does not have a relevant dispute resolution policy for a type of dispute, the following process shall apply: (a) Negotiation. If there is a dispute between the parties relating to or arising out of this Agreement, then within 5 Business Days of a party notifying the other party of a dispute, senior representatives from each party must meet (or discuss directly via the telephone or internet) and use all reasonable endeavours acting in good faith to resolve the dispute by joint discussions; (b) Mediation. If the dispute between the parties relating to or arising out of this Agreement is not resolved within five Business Days of notification of the dispute under Clause 17.1, the parties must agree to submit the dispute to mediation, administered by lawyers engaged in alternative dispute resolution; (c) Court proceedings. A party may not commence court proceedings in relation to a dispute relating to or arising out of this Agreement until it has exhausted the procedures in this clause 17.2 unless the party seeks appropriate injunctive or other interlocutory relief to preserve property or rights or to avoid losses that are not compensable in damages. 18 FORCE MAJEURE 18.1 If a party is prevented in whole or in part from carrying out its obligations under this Agreement as a result of Force Majeure, it will promptly notify the other party accordingly. The notice must: (a) Specify the obligations and the extent to which it cannot perform those obligations; (b) Fully describe the event of Force Majeure; (c) Estimate the time during which the Force Majeure will continue; and (d) Specify the measures proposed to be adapted to remedy or abate the Force Majeure. 18.2 Following a notice of Force Majeure in accordance with clause 18.1 and while the Force Majeure continues, the obligations which cannot be performed because of the Force Majeure will be suspended, other than obligations to pay money that is due and payable. 18.3 The party that is prevented from carrying out its obligations under this Agreement as a result of Force Majeure must remedy the Force Majeure to the extent reasonably practicable and resume performance of its obligations as soon as reasonably possible. 18.4 The party that is prevented from carrying out its obligations under this Agreement as a result of Force Majeure must take all action reasonably practicable to mitigate any loss suffered by the other party as a result of the party's failure to carry out its obligations under this Agreement. 18.5 The term of this Agreement will not be extended by the period of Force Majeure. 19 ELECTRONIC COMMUNICATION AND ASSIGNMENT 19.1 The words in this clause that are defined in the Electronic Transactions Act 1999 (Cth) have the same meaning. 19.2 The User can direct notices, enquiries, and complaints and so forth to the Company as set out in this Agreement. The Company will notify the User of a change of details from time-to-time. 19.3 The Company will send the User notices and other correspondence to the details that the User submits to the Company, or that the User notifies the Company of from time-to-time. It is the User's responsibility to update its contact details as they change. 19.4 A consent, notice or communication under this Agreement is effective if it is sent as an electronic communication unless required to be physically delivered under law. 19.5 Notices must be sent to a party's most recent known contact details. 19.6 The User may not assign or otherwise create an interest in this Agreement without the written consent of the Company. 19.7 The Company may assign or otherwise create an interest in its rights under this Agreement by giving written notice to the User. 20 GENERAL 20.1 Prevalence. Each party to this Agreement agrees to the clauses in the Important Terms and the Special Conditions. The Important Terms, any Special Conditions and the General Conditions form a single legal agreement. To the extent that the Important Terms or the Special Conditions are inconsistent with the General Conditions, the terms of the Important Terms will prevail. To the extent that the Special Conditions are inconsistent with the Important Terms, the Special Conditions will prevail. 20.2 Disclaimer. Each party acknowledges that it has not relied on any representation, warranty or statement made by any other party, other than as set out in this Agreement. 20.3 Relationship. The relationship of the parties to this Agreement does not form a joint venture or partnership. 20.4 Waiver. No clause of this Agreement will be deemed waived and no breach excused unless such waiver or consent is provided in writing. 20.5 Further Assurances. Each party must do anything necessary (including executing agreements and documents) to give full effect to this Agreement and the transaction facilitated by it. 20.6 Governing Law. This Agreement is governed by the laws of the state of Victoria, Australia. Each of the parties hereby submits to the non-exclusive jurisdiction of courts with jurisdiction there. 20.7 Severability. Any clause of this Agreement, which is invalid or unenforceable is ineffective to the extent of the invalidity or unenforceability without affecting the remaining clauses of this Agreement.END GENERAL CONDITIONS
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Yankees Series Review: Really? The Jays Beat Us? Posted on August 31, 2012 August 4, 2014 by Martin Stezano Jobu reviews the Yankees' terrible series against the Toronto Blue Jays. If you couldn't tell by the title, or the summary line, the Yankees played a pretty terrible series against the Blue jays. While they managed to win a game against the last place, minor-league-line-upped Jays, they dropped two. The losses happened because of bad hitting, defense and pitching, so at least the collapse was consistent. Game 1: Blue Jays 8, Yankees 7 The Jays proved too much for the Yankees in game one. (Jeff Zelevansky/Getty Images) I had the pleasure of being at the stadium to witness the Yankees snatch defeat from the jaws of victory in this game. They sent young David Phelps to the mound against Henderson Alvarez (I dubbed him "Hendu"). The Game started out great, but in the end, no untucked shirts. Thank You David The Yankees' starting pitching has been pretty crappy of late. As we wait for Andy Pettitte to come back, and hope that Iván Nova doesn't, it's nice that Phelps has really provided some solid pitching for us at a key time. He pitched well enough to win this game, giving up a couple of homers but mostly getting the Jays out easily. He also had a bunch of PC Richards, which is always great to see. (If you don't know what that is, go to a game and find out). His final line looked like this: 6.1 Ip, 5 H, 4 R, 1 BB, 7 Ks, 88 pitches and a no-decision. (note: the fourth run was allowed by Cody Eppley in relief). The real culprits in this game were Rafael Soriano, who blew the save by allowing a two-out, three-run homer to Colby Rasmus to give the Jays a 7-6 lead in the ninth, and Derek Lowe, whose pickoff throw error gave the Jays the win in the top of the eleventh. Thanks everyone. Not Much You Can Do The Yankees put up seven runs in a game in which their starter only allowed four. That should be enough to win every time out. There really wasn't much they could have done. Canó homered twice, Swisher hit a two-run homer and The Captain tied the game with a leadoff homer in the bottom of the tenth. In all, the Yankees had seven runs on eight hits. They left seven men on base, and only went 1-5 with runners in scoring position, but come on. That's good enough to win. Notable Offense: HR – Canó 2 (27), Swisher (20), Jeter (14), RBI – Canó 2 (70), Martin (35), Ibañez (52), Swisher 2 (75), Jeter (45), 3 hits for Chavez, 2 for Canó Boxscore – 8/27/2012 Game 2: Yankees 2, Blue Jays 1 Hughes was on point in game two. Great job, good effort. (Kathy Kmonicek/AP) The Yankees sent Phil Hughes to the mound against Rick Romero in game two. They didn't get much offense, but got some great pitching and a game two win. Hughesy Poo There really isn't much to write about here. Hughes was pretty great. He did give up a solo home run to Adeiny Hechavarria, but homers are best when they're solo, and the run didn't really make a difference in the game anyway. Hughes' final line looked like this: 7 Ip, 4 H, 1 R, 3 BBs, 5 Ks, 110 pitches and his thirteenth win of the season (13-11). Robertson pitched a solid eighth and a notably surly Soriano rebounded wonderfully with a 123 ninth inning for his 34th save of the year. Just Enough Sometimes you're gonna get shut down. Sure, Ricky Romero hadn't won in his last eleven starts, and he hadn't come particularly close, but he's still Ricky Romero. You know he has the talent to shut offenses down, and he did in this one. It didn't help that, for some reason, Steve Pearce was hitting cleanup and Russell Martin was hitting fifth. I mean really? That's all we have left? Anywho, the Yankees scored single runs in the third (on an RBI single by Swisher_ and in the fourth (on a sac fly by Curtis Granderson). That's all they would need on this night. Notable Offense: RBI – Swisher (76), Granderson (75), SB – Nix (5), 2 hits for Nix This guy had three doubles and a homer? Come on! (Jeff Zelevansky/Getty Images) What can I say about game three that I haven't said all season long? The Yankees had their "Ace" on the mound against J.A. Happ, held two different leads, and still lost the game and the series. Can't wait for the Orioles to come to town if we're playing like this. Bad CC Again As good as Sabathia was against the Indians, he was once again brutal against the Jays, who are equally terrible. For some reason, CC hasn't been able to consistently put together good starts this season. It solidifies Kuroda's status as the new ace and it is very frustrating. The Yankees led 2-0 before CC and the defense let up three in the third, and 4-3 until CC gave the lead up again in the sixth. How can you hand your ace two separate leads and not win? CC's final line looked like this: 7 Ip, 9 H, 5 R (2 earned), 0 BBs, 8 Ks, 99 pitches and his fourth loss of the season (13-4). Girardi somehow used five pitchers to get through the last two innings, and none of them pitched particularly well. They ended up letting the Jays tack on a couple of back=breaking runs late. Oh by the way, Yunel Escobar went 4-5 with three doubles and a home run… I think I've had enough. Terrible Offense I know the Yankees scored five runs in this game, which should pretty much always be enough with CC on the mound, but they weren't very good. The real story in this game wasn't the five runs the Yankees didn't score. It was the ten other ones they probably could have and should have scored but didn't. The Yankees had eight hits and five walks, but slumped terribly with men on base. They left eight guys on and only went 3-17 with RISP. 3-17! This is how they played in April/May when everyone thought they would end up sitting at home in October like the Sox. It's despicable. Notable Offense: RBI – Jones (31), Granderson 3 (78), Martin (36), at least no one strained anything in this game. yikes. I didn't realize the Yankees were just keeping first place warm for the Orioles or Rays this entire season. They've played .500 ball since the break and both of those teams are breathing down their necks. Now that Tex is hurt, and the Yankees have refused to DL him, they'll have to survive a few games with Steve Pearce manning first base against lefties and (I guess?) Nick Swisher against righties. The bullpen, other than Robertson and Soriano, has been awful of late, and they can't seem to get consistent starting pitching out of anyone other than Kuroda and Phelps…. Is it time to panic? Not yet, but the Yankees will host the Orioles this weekend, and still have six games left against the Rays, so that time might come soon. Featured image courtesy of: Rich Schultz/AP Posted in BaseballTagged new york yankees, toronto blue jays, Yankees Series Review ten + 14 =
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Unstable è il secondo album in studio della band statunitense Adema, pubblicato nel 2003 dall'Arista Records. Tracce Traccia bonus nell'edizione giapponese Someone Else's Lies - 3:27 Formazione Mark Chavez - voce Tim Fluckey - chitarra solista Mike Ransom - chitarra ritmica Dave DeRoo - basso Kris Kohls - batteria, percussioni Altri musicisti Deborah Lurie - tastiera in So Fortunate Classifiche Note Collegamenti esterni Album pubblicati dall'Arista Records
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Man found on road in Woking sustained 'serious injuries' due to being drunk, police say He remains in hospital in a serious condition A police cordon in Forge End, Woking on Saturday (March 9) (Image: Will Bradley) A man found lying on the road in Woking on March 8, sustained "serious injuries" due to being "intoxicated", Surrey Police say. He was found by a member of the public at around 5am in Forge End, just off Victoria Way on Friday (March 8). A police cordon remained at the entrance of the road, opposite the Premier Inn, on Saturday morning (March 9). The man, in his 30s, remains in hospital in a "serious condition", according to police. It was originally unclear how the man had suffered the injuries and whether a third party was involved but police have now concluded investigations. A spokesman said: "We have carried out a full and thorough investigation after a man was found with serious injuries in Woking in the early hours of March 8. 8 EastEnders actors that are from Surrey Couple 'violated' after tools stolen New Surrey Heath council leader speaks Man bitten on the arm in Co-Op assault "This has included speaking to witnesses, carrying out house to house enquiries and viewing available CCTV footage. "Following these enquiries, it is not believed there was any third party involvement in how the man sustained his injuries or that he was involved in a collision. "It is believed that the man was intoxicated and that his injuries are consistent with a number of falls." "A member of the public came across the man, who is in his 30s, lying on the side of the road on Forge End, just off Victoria Way, around 5am." "South East Coast Ambulance Service (SECAmb) attended and took him to hospital where he remains in a serious condition." Person dies after being 'hit by a train' near Woking station Officers would still like to speak to anyone who they have not heard from already, who may have seen the man or saw him in the area between 11pm on March 7 and 5am on March 8. The man is described as Nepalese , 5ft 8in, with short black hair. He was possibly wearing a green beanie hat and wearing dark clothing, according to police. Anyone with information is asked to contact Surrey Police on 101 (999 in an emergency) or online quoting reference PR/P19053835. Alternatively, call Crimestoppers anonymously on 0800 555 111 or through its anonymous online form. Join our 'Woking Live' group We've created a Facebook group on all things Woking. This is the perfect place on social media to discuss everything happening in the area. You can join here. Woking town centre
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Research ArticleDEVELOPMENT AND HORMONE ACTION The Transcriptional Repressor ARR1-SRDX Suppresses Pleiotropic Cytokinin Activities in Arabidopsis Alexander Heyl, Eswar Ramireddy, Wolfram G. Brenner, Michael Riefler, Joke Allemeersch, Thomas Schmülling Alexander Heyl Eswar Ramireddy Wolfram G. Brenner Michael Riefler Joke Allemeersch Thomas Schmülling Published July 2008. DOI: https://doi.org/10.1104/pp.107.115436 The signal transduction of the phytohormone cytokinin is mediated by a multistep histidine-to-aspartate phosphorelay system. One component of this system are B-type response regulators, transcription factors mediating at least part of the response to cytokinin. In planta functional analysis of this family is hampered by the high level of functional redundancy of its 11 members. We generated a dominant repressor version of the Arabidopsis (Arabidopsis thaliana) response regulator ARR1 (ARR1-SRDX) using chimeric repressor silencing technology in order to study the extent of the contribution of B-type response regulators to cytokinin activities. In a protoplast test system, ARR1-SRDX suppressed ARR6:β-glucuronidase reporter gene activation by different B-type ARRs. 35S:ARR1-SRDX transgenic Arabidopsis plants showed phenotypic changes reminiscent of plants with a reduced cytokinin status, such as a strongly reduced leaf size, an enhanced root system, and larger seeds. Several bioassays showed that 35S:ARR1-SRDX plants have an increased resistance toward cytokinin. The rapid induction of a large part of the cytokinin response genes was dampened. The transcript levels of more than 500 genes were more than 2.5-fold reduced in 35S:ARR1-SRDX transgenic seedlings, suggesting a broad function of B-type ARRs. Collectively, the suppression of pleiotropic cytokinin activities by a dominant repressor version of a B-type ARR indicates that this protein family is involved in mediating most, if not all, of the cytokinin activities in Arabidopsis. In addition, a role for B-type ARRs in mediating cross talk with other pathways is supported by the resistance of 35S:ARR1-SRDX seeds to phytochrome B-mediated inhibition of germination by far-red light. This study demonstrates the usefulness of chimeric repressor silencing technology to overcome redundancy in transcription factor families for functional studies. The plant hormone cytokinin is involved in many developmental processes and plays a critical role in numerous physiological responses to changes in the environment (Mok and Mok, 2001). In recent years, significant progress has been made toward the understanding of how the cytokinin signal is perceived and transduced (Heyl and Schmülling, 2003; Kakimoto, 2003; Mizuno, 2004; Heyl et al., 2006; Hwang and Sakakibara, 2006; Müller and Sheen, 2007). In the current model, which has been developed mainly in Arabidopsis (Arabidopsis thaliana), the hormone is perceived by membrane-bound hybrid His-kinase receptors, which autophosphorylate upon binding of the hormone ligand. After transphosphorylation within the receptor, the phosphate group is transferred to His phosphotransfer proteins, which subsequently locate to the nucleus, where they activate B-type response regulators (ARRs) via phosphorylation. These transcription factors regulate the transcription of their target genes, one group of which codes for A-type response regulators. A negative feedback on the cytokinin signaling pathway was shown to be mediated by members of this protein class (Hwang and Sheen, 2001; To et al., 2004). Arabidopsis encodes 11 B-type ARRs. They possess, in addition to the response regulator domain, a MYB-class DNA-binding domain (Riechmann et al., 2000). The DNA-binding domains share a high degree of sequence conservation, in particular in the nine amino acids that were identified in ARR10 to be most likely in direct contact with the DNA (Hosoda et al., 2002). Several B-type ARRs have been shown to bind to the same or very similar sequence motifs (Sakai et al., 2000; Hosoda et al., 2002; Imamura et al., 2003). B-type ARRs regulate the transcription of their target genes in response to cytokinin treatment (Sakai et al., 2000; Hwang and Sheen, 2001; Lohrmann et al., 2001; Imamura et al., 2003). Reverse transcription-PCR, microarray, and promoter-GUS fusion experiments have demonstrated that the members of the B-type ARR family have large and overlapping expression domains (Mason et al., 2004; Tajima et al., 2004; Zimmermann et al., 2004; summarized by Heyl et al., 2006). The analysis of B-type ARR mutants has revealed their involvement in cytokinin signaling but also a high degree of functional redundancy (Sakai et al., 2001; Horák et al., 2003; Hass et al., 2004; Mason et al., 2005). Loss-of-function mutants of single B-type ARR genes (ARR1, ARR2, ARR10, ARR11, and ARR18) caused no strong phenotypic alterations. However, different cytokinin response assays showed increasing cytokinin resistance for higher order mutants (Mason et al., 2005; Yokoyama et al., 2007). Surprisingly, besides quantitative changes of the root system and a defect of vascular development in the arr1 arr10 arr12 triple mutant (Mason et al., 2005; Yokoyama et al., 2007), no strong morphological alterations were described. This indicates that the degree of redundancy among B-type ARRs is very high and/or that other transcriptional regulators compensate for the loss of B-type ARRs, such as the cytokinin response factors of the ethylene response factor (ERF) transcription factor family (Rashotte et al., 2006). In order to explore the functions of B-type response regulators, we took advantage of the chimeric repressor silencing technology (CRES-T; Hiratsu et al., 2003). This technology has been developed to study the consequences of silencing of the target genes of single transcription factors and has also been used to overcome the experimental limitations caused by functional redundancy of transcription factor families. In 2001, Ohta and colleagues mapped a repression motif of transcriptional repressors of the class II ERFs (Ohta et al., 2001). This ERF-associated amphiphilic repression motif or variations of it are found in numerous plant transcriptional repressors (Ohta et al., 2001; Tiwari et al., 2004; Kazan, 2006). Further improvement resulted in the SRDX motif (Hiratsu et al., 2003). Fusion of this motif to transcriptional activators converts them into dominant repressors, even in the presence of the original activator domain (Hiratsu et al., 2003). Interestingly, these dominant repressors may repress not only the transcription of their own target genes but also the expression of target genes of other members of their respective gene families and thus overcome functional redundancy (Hiratsu et al., 2003; Mitsuda et al., 2007). In this study, the SRDX motif was fused to the C terminal end of ARR1 and expressed under the control of a 35S promoter in wild-type Arabidopsis plants. The resulting transgenic plants showed a cytokinin deficiency phenotype, including reduced shoot and enhanced root growth, altered reproductive organs, and increased resistance to cytokinin. Molecular analysis revealed the attenuation of early transcriptional responses to cytokinin. The implications for the function of this class of transcription factors are discussed. ARR1-SRDX Suppresses the Cytokinin-Dependent Induction of a Cytokinin Primary Response Gene in Planta A dominant repressor for the B-type ARRs was generated by introducing a 36-bp DNA sequence (5′-CTGGATCTGGATCTGGAACTGCGCCTGGGCTTTGCG-3′) encoding the SRDX domain (LDLDLELRLGFA; Hiratsu et al., 2003) replacing the last 20 nucleotides 5′ of the ARR1 stop codon (Supplemental Fig. S1). ARR1 was chosen as it is the best characterized B-type response regulator in Arabidopsis (Sakai et al., 2000, 2001, Mason et al., 2004, 2005; Taniguchi et al., 2007). The in planta effect of ARR1-SRDX was first examined in a protoplast transactivation assay (Ehlert et al., 2006) using a 1,000-bp promoter fragment upstream of the translational start of ARR6, a primary cytokinin response gene (Hwang and Sheen, 2001), fused to the GUS reporter gene. The addition of cytokinin resulted in a more than 3-fold induction of the reporter gene expression compared with the noninduced condition (Fig. 1A ). Cotransfection with ARR1 under the control of a 35S promoter led to a strong increase in GUS activity even in the absence of cytokinin. The addition of cytokinin caused a further 2-fold increase of the GUS activity, indicating that ARR1 mediates the cytokinin response in this assay. In contrast, the expression of ARR1-SRDX under the control of a 35S promoter effectively suppressed the cytokinin induction of GUS expression. Furthermore, ARR1-SRDX completely abolished the ARR1-caused expression of the reporter gene in the absence and presence of cytokinin (Fig. 1A). The expression of the GUS reporter gene under the control of a 35S promoter was not cytokinin inducible. In the next step, we tested in the same assay system whether other B-type ARRs activate the transcription of the ARR6:GUS reporter and whether this activation could be suppressed by ARR1-SRDX. For these experiments, ARR2 was chosen as this is the B-type ARR most closely related to ARR1. ARR10 and ARR12 were tested as well, as both have been shown to be at least partly functionally redundant to ARR1 (Yokoyama et al., 2007; Ishida et al., 2008). Furthermore, ARR19 and ARR21 were included in the analysis as representatives of the two pairs of more distantly related B-type ARRs. All of these B-type ARRs increased ARR6:GUS expression without cytokinin to a different extent (Fig. 1B). The addition of cytokinin in most cases increased the reporter gene activity further. The coexpression of ARR1-SRDX effectively repressed reporter gene activation by all of the B-type ARRs in the absence and presence of cytokinin (Fig. 1B). These results clearly demonstrate the potential of ARR1-SRDX as a dominant repressor of the primary transcriptional response to cytokinin in planta. 35S:ARR1-SRDX represses the transactivation capacity of B-type ARRs in a protoplast transactivation assay. A, 35S:ARR1-SRDX represses the activation of an ARR6:GUS reporter gene by ARR1. B, 35S:ARR1-SRDX represses the activation of an ARR6:GUS reporter gene by several B-type ARRs. The activation of the ARR6:GUS reporter gene was measured without and 16 h after the addition of 500 nm t-zeatin (tZ). The ARR6:GUS reporter construct and a 35S:GUS construct without any effector plasmid were used as controls. Protoplasts were cotransfected with the ARR6:GUS reporter and an effector plasmid expressing ARR1, ARR2, ARR10, ARR12, ARR19, ARR21, or ARR1-SRDX or two effector plasmids expressing the respective B-type ARR and ARR1-SRDX. Variations in transformation efficiencies were normalized using a 35S:NAN reporter construct. The mean values and sd of four independent transfection assays were calculated and shown as relative GUS/NAN activity units. Transgenic Arabidopsis Plants Expressing a Dominant ARR1-SRDX Repressor Next, we established transgenic lines by transforming the 35S:ARR1-SRDX gene into wild-type Columbia (Col-0) plants. Because B-type ARR expression was detected in virtually all tissues investigated (Heyl et al., 2006) and we aimed to study the effects of the repression of as many B-type ARRs as possible (not just ARR1 in the ARR1 expression domain), we purposefully chose the 35S promoter to drive gene expression. The 35S promoter has been previously used successfully in combination with CRES-T (Koyama et al., 2007). More than 10 independent transgenic lines with a similar phenotype, but distinct from the wild type, were recovered (Supplemental Fig. S2). Two of those lines, ARR1-S-8 and ARR1-S-10, which showed a characteristic phenotype with different expressivity, were characterized in more detail. Experiments were carried out with homozygote and phenotypically uniform progeny. Northern-blot analysis using a SRDX-specific probe showed the expression of the ARR1-SRDX transcript in both lines (Fig. 2A ). The steady-state transcript level was higher in ARR1-S-8 compared with ARR1-S-10 (Fig. 2A). In order to check whether the transcript level of the ARR1 gene itself was altered in the transgenic lines, we compared its level with the wild type using a probe that specifically recognizes the wild-type ARR1 but not ARR1-SRDX transcripts. This analysis revealed an increased ARR1 transcript level in both 35S:ARR1-SRDX transgenic lines, indicating a feedback regulation of ARR1 (Fig. 2B). This increase in transcript level was specific for ARR1 and did not affect four other B-type ARR genes, which were detectable in our microarray experiments (see below) and showed similar transcript levels in the transgenic lines and the wild type. Expression of the 35S:ARR1-SRDX gene fusion and of the ARR1 gene. A, Total RNA samples were isolated from 3-week-old plants, and the transcript was detected by northern-blot hybridization using a probe specific for the ARR1-SRDX gene fusion. The ACTIN2 transcript was used as a loading control. WT, Wild-type Col-0; ARR1-S-8 and ARR1-S-10 are independent lines of 35S:ARR1-SRDX transgenic plants. B, Analysis of ARR1 transcript levels. Total RNA was isolated from 5-d-old wild-type and 35S:ARR1-SRDX transgenic seedlings. Northern blots were hybridized with a probe specific for that C-terminal part of ARR1 that had been deleted during the construction of the 35S:ARR1-SRDX gene and thus hybridizes only with the native ARR1 and not with the ARR1-SRDX fusion transcript. Total RNA was used as a loading control. 35S:ARR1-SRDX Transgenic Plants Display a Pleiotropic Shoot Phenotype Transgenic plants expressing the 35S:ARR1-SRDX construct displayed a strong pleiotropic shoot phenotype, with a higher expressivity in line ARR1-S-8 than in line ARR1-S-10 (Fig. 3A ). Plants were generally smaller, and after flowering numerous individuals showed to a varying degree enhanced branching of the shoot. The leaves of the dominant repressors were strongly reduced in both size and number compared with wild-type plants. In the stronger expressing line ARR1-S-8, the true leaves were only about the size of the cotyledons in the wild type (Fig. 3B). Twenty days after germination (DAG), the wild-type plant had on average nine rosette leaves, while the ARR1-SRDX-expressing plants had only seven leaves at that time point (Fig. 3C). Shoot phenotype of 35S:ARR1-SRDX transgenic plants. A, Shoot phenotype of transgenic 35S:ARR1-SRDX plants at 35 DAG compared with the wild type. B, Leaf phenotypes of a plant of line ARR1-S-8 and of a wild-type plant at 20 DAG. The leaves on the left are the cotyledons, followed by the true leaves in order of their formation. C, 35S:ARR1-SRDX transgenic plants have formed fewer leaves than the wild type at the onset of flowering. The total number of rosette leaves was counted at 19 DAG. Error bars represent sd (n ≥ 20). Pairwise Student's t test was used to compare values with the wild-type. **, 0.001 < P < 0.01. ARR1-S-8 and ARR1-S-10 are two independent lines of 35S:ARR1-SRDX transgenic plants. [See online article for color version of this figure.] 35S:ARR1-SRDX Plants Develop an Enlarged Root System In contrast to the reduced shoot size, 35S:ARR1-SRDX transgenic plants showed a generally enhanced root system compared with the wild type (Fig. 4A ). While the ARR1-S-8 plants had only a slightly longer primary root than the wild type at 10 DAG, the primary root of line ARR1-S-10 was more than 30% longer (34.9 ± 3.1 mm in the wild type compared with 51.9 ± 6.6 mm in line ARR1-S-10; Fig. 4B). The difference between the transgenic lines and the wild type was also marked in the number of lateral roots. At 10 DAG, plants of line ARR1-S-8 had developed about twice as many lateral roots as the wild type and line ARR1-S-10 had about three times more (13.2 ± 1.9 lateral roots compared with 4.8 ± 1.1 lateral roots in the wild type; Fig. 4C). Root phenotype of 35S:ARR1-SRDX transgenic plants. A, Transgenic plants show longer and more branched roots than wild-type plants. Seedlings were grown vertically on MS medium plates. The photograph was taken at 10 DAG. Bar = 1 cm. B, 35S:ARR1-SRDX transgenic plants produce longer primary roots than wild-type plants. The length of the primary root was determined at 10 DAG. C, 35S:ARR1-SRDX transgenic plants produce more lateral roots compared with the wild type. The number of emerged lateral roots was determined at 10 DAG. Results shown in B and C represent means from at least three independent replicates for each line. Error bars represent sd (n ≥ 15). Pairwise Student's t test was used to compare values with the wild type. **, 0.001 < P < 0.01. ARR1-S-8 and ARR1-S-10 are two independent lines of 35S:ARR1-SRDX transgenic plants. [See online article for color version of this figure.] Reproductive Development of 35S:ARR1-SRDX Plants Is Altered The 35S:ARR1-SRDX transgenic plants flowered earlier than wild-type plants (Fig. 5A ). In the wild type, the first flower buds opened at 19 DAG. In contrast, both transgenic lines flowered at around 14 DAG (Fig. 5B). In the 35S:ARR1-SRDX transgenic plants, all reproductive organs were reduced in size. This was more pronounced in line ARR1-S-8, in which the flowers were only half the size of the wild-type flowers (Fig. 5C). The smaller flowers of the 35S:ARR1-SRDX plants gave rise to smaller siliques. The length of the siliques of line ARR1-S-8 was about 30% of the length of the wild-type siliques. The shape differed also from the wild type, as it was twisted and crooked (Fig. 5D). The phenotype of line ARR1-S-10 was weaker, as the reduction of the silique size was not as dramatic as in line ARR1-S-8, and the shape resembled more that of the wild type (Fig. 5D). While the number of seeds obtained by selfing was considerably lower in the 35S:ARR1-SRDX plants (data not shown), the seeds themselves showed increased size (Fig. 5E). Their weight was 40% and 50% higher in the lines ARR1-S-8 and ARR1-S-10, respectively (Fig. 5F). Reproductive development of 35S:ARR1-SRDX transgenic plants. A, Flower induction occurs earlier in 35S:ARR1-SRDX transgenic plants compared with wild-type plants. The plants were grown under long-day conditions and photographed at 19 DAG. B, Quantitative analysis of the early-flowering phenotype of 35S:ARR1-SRDX transgenic plants. The graph shows the time (DAG) of flower bud opening in transgenic plants compared with the wild type. C, Flower morphology of 35S:ARR1-SRDX transgenic plants compared with the wild type. D, Siliques of 35S:ARR1-SRDX transgenic plants compared with wild-type plants. E, Seeds of 35S:ARR1-SRDX transgenic lines compared with the wild type. F, The seeds of 35S:ARR1-SRDX transgenic plants have increased weight. Seed weight was determined by weighing 10 pools of 200 seeds for each line. Error bars represent sd. Bars in C to E = 1.0 mm. Pairwise Student's t test was used to compare values with the wild type. ***, P < 0.001. ARR1-S-8 and ARR1-S-10 are two independent lines of 35S:ARR1-SRDX transgenic plants. [See online article for color version of this figure.] The Cytokinin Response of 35S:ARR1-SRDX Plants Is Altered in Shoots and Roots As the phenotype of the 35S:ARR1-SRDX plants is reminiscent of plants with reduced cytokinin signaling (Higuchi et al., 2004; Nishimura et al., 2004; Riefler et al., 2006), we carried out several cytokinin sensitivity assays. Cytokinin is known to delay the onset of leaf senescence and to increase the chlorophyll retention in detached leaves incubated in the dark (Richmond and Lang, 1957; Riefler et al., 2006). Detached wild-type leaves kept in the dark for 10 d lost more than 80% of their chlorophyll compared with fresh leaves (Fig. 6A ). The addition of increasing amounts of cytokinin reversed this effect. In wild-type leaves, 0.1 μm 6-benzyladenine (BA) strongly increased chlorophyll retention, and at 5 μm BA the chlorophyll level of dark-incubated detached leaves was similar to that in fresh leaves. In contrast, while in both 35S:ARR1-SRDX lines the loss of chlorophyll under dark conditions was similar to that in the wild type, the addition of cytokinin to the medium caused only a minor increase in chlorophyll retention, even at the highest concentration (Fig. 6A). This indicates that the cytokinin sensitivity in the leaves had been almost completely lost. 35S:ARR1-SRDX plants are less sensitive to cytokinin. A, Chlorophyll retention in dark-incubated leaves by cytokinin. Fully expanded leaves were excised from 24-d-old plants and floated for 10 d in the dark on water supplemented with various concentrations of cytokinin before the chlorophyll concentration was determined. Time 0 indicates the chlorophyll concentration at the beginning of the experiment. B, Cytokinin sensitivity of primary root elongation. Root elongation was measured for each line between 4 and 9 DAG. The root elongation of each line is expressed as a percentage of its DMSO control. The original data for the transgenic lines were significantly different from the wild-type data, with 0.001 < P < 0.01 as calculated by pairwise Student's t test. C, Cytokinin sensitivity of lateral root formation. The number of lateral roots was determined following growth on vertical plates for 9 DAG. The number of lateral roots between the wild type and the transgenic lines was significantly different (P < 0.01). Error bars represent sd (n ≥ 15). ARR1-S-8 and ARR1-S-10 are two independent lines of 35S:ARR1-SRDX transgenic plants. To investigate the cytokinin response in roots, seedlings of the wild type and the 35S:ARR1-SRDX lines were grown on medium containing increasing amounts of cytokinin. On control medium without cytokinin, the transgenic seedlings developed a longer primary root compared with the wild type (Fig. 4A). The relative difference in root length increased with increasing cytokinin concentrations (Fig. 6B). Seedlings of line ARR1-S-8 displayed a higher resistance to cytokinin than line ARR1-S-10. A 50% inhibition of root elongation was achieved by an approximately 5-fold higher cytokinin concentration. However, the sensitivity to cytokinin, while being clearly reduced, was not completely eliminated in either ARR1-SRDX line (Fig. 6B). Subsequently, we tested whether lateral root formation was altered in the presence of the hormone. In all seedlings, the addition of cytokinin to the medium led to a dramatic decrease in the number of lateral roots (Fig. 6C). But whereas the lateral root formation of the wild type was almost totally repressed at 0.01 μm BA, lateral root formation of both 35S:ARR1-SRDX lines was only halved at this cytokinin concentration. At 0.1 μm BA, the wild type was unable to produce lateral roots, while the dominant repressor lines still showed a significant number (Fig. 6C). 35S:ARR1-SRDX Plants Show a Reduced Induction of Cytokinin Response Genes The phenotypic changes and cytokinin bioassays described above report altered long-term responses to the hormone. To analyze whether rapid cytokinin responses were also altered in the 35S:ARR1-SRDX transgenic lines, the expression of two known primary cytokinin response genes was tested. The transcript levels of ARR5 and ARR7, which both encode A-type ARRs, are direct targets of the B-type ARRs and rapidly induced by cytokinin (D'Agostino et al., 2000; Romanov et al., 2002; To et al., 2004). Both genes were rapidly and strongly induced in wild-type seedlings following the application of cytokinin. This induction was strongly diminished in both transgenic lines (Fig. 7A ). 35S:ARR1-SRDX gene expression dampens the early cytokinin response. A, Northern-blot analysis of ARR5 and ARR7 transcript levels. Total RNA was isolated from 5-d-old wild-type and 35S:ARR1-SRDX seedlings before treatment and after 15, 30, and 120 min of treatment with 5 μm BA. Northern blots were hybridized with a probe specific for the cytokinin response genes ARR5 and ARR7. The ACTIN2 gene was used as a loading control. B, Interaction plots of A-type ARR genes. Interaction plots show the relative normalized expression values for all seven A-type ARR genes present on the CATMA V2.4 array plotted against the time points of cytokinin treatment: BA0 (control), BA15 (15 min of BA treatment), and BA120 (120 min of BA treatment). The table in the lower right corner shows the significance of differences in gene expression. C (cytokinin effect) represents the responsiveness of the respective gene to cytokinin treatment. G (genotype effect) denotes whether the average expression of the respective gene in line ARR1-S-8 differs significantly from that in the wild type. The cytokinin response of genes with a significant I (interaction effect) is dependent on the genotype. The significance codes are based on the uncorrected P value for each gene. Symbols are as follows: no symbol, P > 0.05; *, 0.01 < P < 0.05; **, 0.001 < P < 0.01; ***, P < 0.001. Transcriptome Analysis Reveals Complex Changes in 35S:ARR1-SRDX Plants Next, we investigated the changes occurring at 15 and 120 min following cytokinin treatment of 5-d-old seedlings in the transcriptome of the wild type and line ARR1-S-8 using the CATMA V2.4 array. Seedlings of both genotypes show only minor morphological differences at this stage. In all experiments, we regarded genes in which the expression was changed by ≥2.5-fold, the false discovery rate (FDR)-corrected P value (q value) was ≤0.05, and that had 50% or more spots above background in the higher expressed condition as significantly regulated. In total, 658 genes were found with a lower steady-state mRNA level and 505 genes were found with a higher steady-state mRNA level in seedlings of line ARR1-S-8 compared with the wild type (Table I ; Supplemental Table S1). Examples of down-regulated and up-regulated genes in 35S:ARR1-SRDX transgenic seedlings Steady-state mRNA levels of seedlings of the wild type and line ARR1-S-8 were analyzed at 5 DAG. The data are sorted according to the ratio. The rank in the table of all significantly regulated genes (>2.5-fold difference, q < 0.05) is given. The q value is the FDR-corrected P value and was calculated as described (Benjamini and Hochberg, 1995). First we analyzed whether the expression of known ARR1 target genes was altered. Eleven of the 23 ARR1 target genes described by Taniguchi et al. (2007) were also on our array and could be detected. All of these were also induced in the wild type under our conditions, 10 showed a diminished and/or delayed induction in the 35S:ARR1-SRDX plants, and seven showed a lower basal expression level in the 35S:ARR1-SRDX plants compared with wild-type plants (Supplemental Table S2). Together, this shows a significant repressive influence of ARR1-SRDX at least on ARR1 target gene expression. Target genes of other B-type ARRs could not be analyzed as they are mostly not known. We then studied broader cytokinin-induced changes in the transcript abundance, which should reveal whether there is an overall dampening of the cytokinin response or whether specific changes could be observed. In 35S:ARR1-SRDX transgenic seedlings, the total number of genes up-regulated by cytokinin treatment was about half the number observed in the wild type (Supplemental Table S1). The induction of the 10 strongest cytokinin-regulated genes in the wild type was reduced in line ARR1-S-8 to 6% and 30% after 15 and 120 min, respectively (Supplemental Table S1). Comparison of other subsets of up-regulated genes between the wild type and 35S:ARR1-SRDX transgenic seedlings yielded similar results. For example, the response to cytokinin of the majority of the seven A-type ARR genes that are represented in the CATMA V2.4 array was dampened and/or delayed (Fig. 7B), which is consistent with the result of the northern-blot analysis (Fig. 7A). However, the response curves show individual differences. For example, for ARR4 and ARR16, the early increase of transcript abundance seen in the wild type is completely missing in the 35S:ARR1-SRDX transgenic seedlings. Other genes, like ARR6 and ARR7, show a weaker response at the early time point (Fig. 7B). In total, 73% of the genes induced by cytokinin in the wild type were not induced in line ARR1-S-8. We then checked whether genes that are down-regulated by cytokinin would show enhanced repression in 35S:ARR1-SRDX seedlings. Analysis of a set of 56 early or late cytokinin down-regulated genes (Brenner et al., 2005) revealed only five examples that show a stronger down-regulation following cytokinin treatment in the 35S:ARR1-SRDX seedlings compared with the wild type. In addition, this concerned only genes that were down-regulated at 2 h after cytokinin treatment but none of the genes that were rapidly (15 min) down-regulated. This result argues against the possibility that ARR1-SRDX enhances a putative repressor function of ARR1. Analysis of the classes of genes and individual genes that are constitutively down-regulated in 35S:ARR1-SRDX plants should yield indications about the direct or indirect regulatory functions of B-type ARRs. There are numerous genes in line ARR1-S-8 that showed only one-tenth or even less of their wild-type transcript level, indicating that they are directly or indirectly regulated by B-type ARRs. Prominent examples are the nitrate reductase gene NR2 and the ammonium transporter gene AMT2, the nitrate transporter gene NTL1, two sugar transporter genes (STP1 and STP4), and the genes encoding the repressors of GA responses, RGA1 and RGA2 (Table I; Supplemental Table S1). Among the individual genes that were very strongly up-regulated in ARR1-S-8 is a gene encoding an ELIP (for early light-induced protein) of the chlorophyll a/b-binding protein family and the cyclin-dependent kinase inhibitor gene ICK2. Among the cytokinin-related genes, IPT5 was 2.5-fold up-regulated (Table I; Supplemental Table S1). The Ethylene Response of 35S:ARR1-SRDX Seedlings The large number of differentially expressed genes in the 35S:ARR1-SRDX transgenic seedlings indicates the possibility that this family of transcription factors might not have a function solely in cytokinin signaling but also in other pathways. An involvement of the B-type ARR2 in ethylene signaling has been discussed (Hass et al., 2004; Mason et al., 2005). To test the possible involvement of B-type ARRs in mediating the ethylene response, the growth response of 35S:ARR1-SRDX seedlings on medium containing the ethylene precursor 1-aminocyclopropane-1-carboxylic acid (ACC) was compared with that in wild-type seedlings. The hypocotyl lengths of wild-type and 35S:ARR1-SRDX seedlings decreased with increasing concentrations of ACC in the medium (Fig. 8A ). In contrast to the wild type, in which hypocotyl length decreased more with further increasing ACC concentrations, the 35S:ARR1-SRDX seedlings showed resistance to ACC concentrations greater than 1 μm, as their hypocotyl length did not decrease further (Fig. 8A). However, root shortening of wild-type and 35S:ARR1-SRDX seedlings was similar at low and high ethylene concentrations (Fig. 8B). Also, the bending of the apical hook did not differ between the genotypes (data not shown). Hypocotyl and root elongation of 35S:ARR1-SRDX transgenic seedlings in response to ethylene. A, Hypocotyl elongation of 35S:ARR1-SRDX transgenic seedlings on ACC-containing medium compared with the wild type. Transgenic seedlings show resistance at higher concentrations of ACC. Seedlings were placed on vertical MS medium plates containing 0.1, 1.0, 10, or 30 μm ACC. Hypocotyl lengths were measured after 4 d of dark incubation. B, Primary root elongation of 35S:ARR1-SRDX transgenic plants on ACC-containing medium. Root elongation was inhibited to a similar extent in both wild-type and transgenic seedlings. Seedlings were grown on medium containing 10 μm ACC for 4 d in the dark. More than 15 seedlings in two replicates were analyzed for each genotype. Error bars represent sd (n ≥ 15). Pairwise Student's t test was used to compare values with the wild type. *, 0.01 < P < 0.05; **, 0.001 < P < 0.01. ARR1-S-8 and ARR1-S-10 are two independent lines of 35S:ARR1-SRDX transgenic plants. Germination of 35S:ARR1-SRDX Seeds Is Resistant to Inhibition by Far-Red Light Several experiments have indicated an involvement of the two-component signaling system in red light signaling (Sweere et al., 2001; To et al., 2004; Riefler et al., 2006, Mira-Rodado et al., 2007). We used a seed germination assay to explore the possible role of B-type ARRs in response to red light. Far-red light inhibits seed germination, a response that is, under our experimental conditions, mediated by phytochrome B and reversible by red light (Shinomura, 1997; Sullivan and Deng, 2003). The germination behavior of 35S:ARR1-SRDX transgenic seeds and wild-type seeds in white light was similar. At 48 and 60 h after transfer from cold treatment to room temperature, a similar percentage of the seeds of all genotypes had germinated and eventually reached about 100%, indicating that there was no marked difference in the timing or capability of germination (Fig. 9A ). Similarly, about 100% of the seeds germinated after a white light pulse or a red light pulse of 5 min followed by a dark period of 7 d (Fig. 9B). However, when wild-type seeds were exposed to a 5-min far-red light pulse prior to dark incubation, only around 10% of the seeds germinated (Fig. 9B). In contrast, 35% and 60% of the seeds of lines ARR1-S-8 and ARR1-S-10, respectively, germinated following this treatment. A similar difference between the wild type and the transgenic lines was seen when the far-red light treatment was preceded by a 5-min red light pulse. Then, the germination rate of the transgenic lines reached about 80%, while it remained around 10% for wild-type seeds (Fig. 9B). Germination behavior of 35S:ARR1-SRDX seedlings under different light conditions. A, Germination rate after treatment by a white light pulse (5 min, 30 μE) and subsequent incubation in the dark. B, Germination rate after red (R), far-red (FR), or R/FR treatment. Seedlings were treated for 5 min with the indicated light and kept subsequently in the dark. Germination frequency was determined from batches of approximately 100 seeds after 7 d of dark incubation (n = 2). Error bars represent sd. Pairwise Student's t test was used to compare values with the wild type. No symbol, P > 0.05; *, 0.01 < P < 0.05; **, 0.001 < P < 0.01; ***, P < 0.001. ARR1-S-8 and ARR1-S-10 are two independent lines of 35S:ARR1-SRDX transgenic plants. Application of the CRES-T Results in a Dominant Negative Effect and Thus Allows the Investigation of B-Type ARR Functions Previous studies have shown the involvement of several members of the B-type ARRs in mediating cytokinin signaling (Imamura et al., 2003; Tajima et al., 2004; Mason et al., 2005; Yokoyama et al., 2007). However, because of a high degree of functional redundancy, the extent of their contribution was unclear. Here, we have shown that a dominant repressor form of a B-type ARR, ARR1-SRDX, causes a strong cytokinin deficiency phenotype, which is most likely due to the concerted repression of the activities of ARR1 and related transcription factors. This suggests that the activity of B-type ARRs is involved in most, if not all, of the cytokinin-regulated processes. The results of the protoplast transactivation assay clearly demonstrate the dominant negative effect of the ARR1-SRDX protein on ARR1-dependent activation of a reporter gene as well as its induction by cytokinin (Fig. 1A). This dominant negative activity also suppressed the activity of all other B-type ARRs tested (Fig. 1B), further validating the chosen approach. The transcript level of the resident ARR1 gene was even enhanced in the 35S:ARR1-SRDX transgenic plants, indicating that the observed changes of gene expression and plant morphology were not due to cosuppression. The phenotypic changes described here were not observed in 35S:ARR1-overexpressing plants (Sakai et al., 2001; our unpublished data), making it unlikely that nonspecific negative effects such as transcriptional squelching (Kornberg, 2005) contribute to the phenotype. Importantly, the phenotypic changes occur in tissues expressing B-type ARR genes. Binding sites of several B-type ARRs are similar but not identical (Imamura et al., 2003). It is likely, therefore, that ARR1-SRDX suppresses the activity of most if not all B-type ARRs, which is supported by the results of the protoplast transactivation assay (Fig. 1B). However, we cannot completely exclude that part of the changes in phenotype and gene regulations caused by ARR1-SRDX are off-target effects due to interference with other related transcription factors. Candidates are the MYB domain-containing pseudo response regulators APRR2 and APRR4, which show in their DNA binding domains similarity to B-type ARRs, but nothing is known about the function of these APRRs (Makino et al., 2000). Recent experiments have indicated that the DNA motif necessary for ARR1 binding is actually longer than previously reported (Taniguchi et al., 2007), making it less likely that the effect of the ARR1-SRDX dominant repressor spreads far beyond the B-type ARRs. One also has to be aware that individual B-type ARRs are likely to have different functions and that some of the phenotypes seen in the 35S:ARR1-SRDX transgenic plants might be due to the repression of specific ARRs or combinations thereof and do not indicate functions for all members of this protein family. However, taken together, the phenotypic characteristics of the 35S:ARR1-SRDX plants clearly demonstrate that the CRES-T is useful to study larger transcription factor families and can be applied to study other regulatory pathways involving transcriptional regulators hampered by redundancy (Koyama et al., 2007). The Morphological Phenotype of 35S:ARR1-SRDX Plants Is Consistent with a Broad Function of B-Type ARRs in Cytokinin Signaling The phenotype of the 35S:ARR1-SRDX transgenic plants resembled in various aspects the phenotype of cytokinin receptor triple mutants and cytokinin-deficient plants (Werner et al., 2003; Yang et al., 2003; Higuchi et al., 2004; Nishimura et al., 2004; Riefler et al., 2006; Supplemental Fig. S3). As in those mutants, the shoot growth and in particular leaf size were strongly reduced, while seed size and the root system were enlarged. An exception to the similarities between 35S:ARR1-SRDX plants and plants with a reduced cytokinin status is the early-flowering phenotype, which contrasts with the retarded flowering reported for triple receptor mutants and cytokinin-deficient plants (Werner et al., 2003; Higuchi et al., 2004; Nishimura et al., 2004; Riefler et al., 2006). Earlier flowering in 35S:ARR1-SRDX plants was developmentally regulated, as fewer leaves had formed at the onset of flowering. This indicates that this function may be cytokinin-independent, as cytokinin deficiency causes only minor changes in leaf number at the onset of flower formation (Werner et al., 2003). A cytokinin-independent role in flowering has been suggested for the rice B-type response regulator gene Edh1 (Doi et al., 2004). Interestingly, arr2 mutant plants also flower earlier than wild-type plants, indicating a negative regulatory function of ARR2 in the induction of flowering (Hass et al., 2004). It could be that the early-flowering phenotype of the 35S:ARR1-SRDX plants is at least partially due to the suppression of ARR2 function, which was demonstrated in the protoplast transactivation assay (Fig. 1B). 35S:ARR1-SRDX Plants Show Specific Changes of Cytokinin Sensitivity A decreased cytokinin sensitivity of the 35S:ARR1-SRDX transgenic plants was detected in several bioassays. 35S:ARR1-SRDX plants showed complete resistance to cytokinin in the chlorophyll retention assay, which is similar to the phenotype of ahk2 ahk3 receptor mutants (Riefler et al., 2006). This indicates that the cytokinin activities in regulating chlorophyll retention are entirely dependent on B-type ARRs. In particular, ARR2, the closest homolog of ARR1, has been shown to play a role in mediating cytokinin-dependent chlorophyll retention (Kim et al., 2006) and thus may be suppressed in leaves of 35S:ARR1-SRDX plants. The reduction of cytokinin sensitivity was less pronounced in roots of 35S:ARR1-SRDX plants. One possibility to explain this distinction is that different sets of B-type ARRs act in shoots and roots and that the B-type ARRs in the roots are less affected by the dominant repressor activity of ARR1-SRDX. Alternatively, the affected B-type ARRs could play antagonistic roles in the root. The latter possibility is supported by the observation that the inclusion of an arr2 knockout allele in arr mutant combinations causes a reduction in the strength of the root phenotype, indicating that ARR2 might have an antagonistic function to the other B-type ARRs in regulating root elongation and root branching (Mason et al., 2005). Therefore, reduced activity of ARR2 in the dominant repression plants could explain the somewhat weaker root phenotype in the 35S:ARR1-SRDX transgenic plants. Early Cytokinin Responses Are Attenuated in 35S:ARR1-SRDX Seedlings The expression and inducibility of A-type ARR genes and other early cytokinin response genes, which have been shown to be direct target genes of B-type ARRs in the past (Hwang and Sheen, 2001; Taniguchi et al., 2007), were dampened in 35S:ARR1-SRDX transgenic seedlings (Fig. 7; Supplemental Table S1). This clearly shows that the ARR1-SRDX protein suppresses the activation of direct target genes of endogenous B-type ARRs. Interestingly, the response of the majority of the response genes was generally reduced, but each to a different extent. These differences may reflect the different contributions of ARR1 and related B-type ARRs to the cytokinin-dependent regulation of the respective genes. Furthermore, recent work has shown that the transcription of A-type ARRs is also regulated via a B-type ARR-independent pathway. The target genes of the cytokinin response factors of the ERF family of transcription factors partially overlap with those of the B-type ARRs (Rashotte et al., 2006). We have identified large sets of genes that show significant changes in their transcript levels in association with the cytokinin deficiency syndrome of the 35S:ARR1-SRDX plants. The function of the deregulated genes can be linked, in many cases, to known functions of cytokinin in plant physiology and development, such as nitrogen metabolism (Sakakibara et al., 2006) and GA action (Brenner et al., 2005; Jasinski et al., 2005). The fact that the transcript levels of genes related to these processes (e.g. NR2, AMT2, NTL1, RGA1, and RGA2; Table I) change in plants with repressed B-type ARR functions confirms that cytokinin plays an important role in the control of these processes and that the B-type ARRs are at least partly involved in this regulation. This data set will be an important source to identify and study processes downstream of B-type ARRs. B-Type ARRs Are Possible Nodes for the Integration of Different Signaling Pathways As developmental programs are subject to fine-tuning by different factors, the integration of different signaling pathways is necessary. Evidence for a function for B-type ARRs in cross talk came from the red light experiments. Red light is a key regulator of seed germination, and its effect is mediated by phytochromes (Shinomura, 1997; Sullivan and Deng, 2003). Red light stimulates seed germination, while far-red light is inhibitory. The response under our light regime is mediated by phytochrome B, and the reversibility of red light-stimulated germination by far-red light is a hallmark of its activity (Shinomura, 1997). This reversibility was almost completely lost in 35S:ARR1-SRDX transgenic seeds (Fig. 9B). This result is consistent with the previously described reduced far-red light sensitivity of cytokinin receptor mutant seeds (Riefler et al., 2006) and seeds of cytokinin-deficient plants (data not shown). A plausible explanation is that cytokinin in an unknown way alters the Pfr-Pr ratio of phytochrome B (e.g. by stabilization of the active Pfr form). This may be mediated directly by downstream factors such as A-type ARRs, as was proposed for red light-dependent regulation of hypocotyl elongation (Sweere et al., 2001; Mira-Rodado et al., 2007). The dominant repressor effect of ARR1-SRDX could block the cytokinin signal involved in regulating this process. Alternatively, B-type ARRs may be involved in regulating red light responses independent of cytokinin (e.g. by acting downstream of phytochromes). In any case, there is now considerable evidence that the cytokinin status has a strong influence on the reaction to red light. Using the CRES-T, we generated a dominant repressor of B-type ARR function and demonstrated that this approach is useful to overcome functional redundancy in this transcription factor family. Overall, we show that B-type ARRs are required for normal growth and development of the shoot and root, where they exert positive and negative regulatory functions. Comparisons with the phenotypes of cytokinin receptor mutants and cytokinin-deficient plants clearly show that the B-type ARRs, collectively, are involved in regulating most cytokinin-dependent processes in Arabidopsis. 35S:ARR1-SRDX transgenic plants and the data sets of deregulated genes will be a valuable tool for further investigation of the function of this class of transcription factors, in particular of their role in mediating the cross talk of the two-component signaling system with other pathways. Plant Material and Growth Conditions Plants of the Col-0 accession of Arabidopsis (Arabidopsis thaliana) were used as the wild type. The plants were grown in the greenhouse on soil at 22°C under long-day conditions (16 h of light/8 h of dark). For in vitro experiments, seeds were surface sterilized with saturated calcium hypochlorate solution. After sowing, they were kept at 4°C for 3 d in the dark and then exposed to white light (approximately 75 μE). Seedlings were grown at 22°C on medium containing 1× Murashige and Skoog (MS) salts, 3% Suc, 0.05% MES, and 0.9% agar (Merck) unless specified otherwise. For ethylene and red light experiments, Suc was omitted from the medium. For the flowering phenotype, the total number of rosette leaves was counted upon flower bud initiation. Gene Cloning and Transformation The protein-coding region of the ARR1 gene was amplified by PCR using a cDNA library from Arabidopsis C24 (Minet et al., 1992) and inserted in the plasmid pDONR201 (Invitrogen), yielding pDONR201-ARR1 (Dortay et al., 2006). The DNA fragment coding for the SRDX peptide (LDLDLELRLGFA) was synthesized with a TAA stop codon and a BsrGI restriction site at the 3′ end and an in-frame HhaI site at the 5′ end. The ARR1 gene was isolated from the plasmid pDONR201-ARR1 by restriction digestion with BsrGI, and the resulting fragment was further digested with HhaI. The DNA fragments were ligated and recloned into pDONR201. The resulting ARR1-SRDX gene was shuttled into the vector pB2GW7 (Karimi et al., 2002) for overexpression under the control of the 35S promoter. This construct was transformed using Agrobacterium tumefaciens-mediated transformation into Arabidopsis plants by the floral dip method (Clough and Bent, 1998). For the protoplast assay, the reporter plasmid was generated by amplifying the 1,000-bp fragment directly upstream of the ARR6 gene (for primers used, see Supplemental Table S3). The resulting PCR product was digested with HindIII and XbaI and ligated into the pBT10-GUS vector (Sprenger-Haussels and Weisshaar, 2000). The B-type ARR overexpression constructs were generated by shuttling the respective genes from the pDONR vector into the pB2GW7 vector (Karimi et al., 2002) for expression under the control of the 35S promoter. All B-type ARR genes were cloned as cDNAs, except for ARR2, which was a genomic clone (for primers used, see Supplemental Table S3). Protoplast Transformation and GUS Assays Protoplast isolation and transformation were carried out according to the method described by Hwang and Sheen (2001). For isolation of mesophyll protoplasts, 4- to 5-week-old rosette leaves were used. Transformation of protoplasts was mediated by 40% polyethylene glycol solution. For cytokinin treatment, protoplasts were incubated overnight with 500 nm trans-zeatin. For the transactivation assays, 9 μg of the ARR6:GUS reporter plasmid and 14 μg of each effector plasmid carrying 35S:ARR1 or other B-type ARRs and 35S:ARR1-SRDX were used. For normalization, 3 μg of a plasmid harboring the 35S:NAN gene (Kirby and Kavanagh, 2002) was added. Both GUS and NAN enzyme assays were performed according to Kirby and Kavanagh (2002). The ratios of GUS and NAN activities were calculated as relative GUS/NAN activity units. Gene Expression Analysis by Northern Blot Total RNA was extracted from 3-week-old soil-grown plants (Fig. 2) or 5-d-old seedlings grown in 0.5× MS liquid medium (Fig. 7A). Seedlings were treated with 5 μm BA and incubated at 0, 15, 30, and 120 min prior to harvesting. Preparation of total RNA and northern-blot analysis were performed as described (Brenner et al., 2005). For northern-blot analysis, 20 μg of RNA was separated on a denaturing agarose-formaldehyde gel (1.2%) containing 10% of 10× MOPS and 3% of 37% formaldehyde, transferred to a Hybond-N+ nylon membrane (Amersham), and after fixation hybridized with radioactive [α-32P]dCTP-labeled DNA. Hybridization was performed at 68°C in a phosphate buffer containing 7% SDS and 1% bovine serum albumin. Washing was done with 2× SSC and 0.2× SSC, 0.1% SDS at 65°C. As a control for loading, blots were reprobed with an ACTIN2 probe. The different probes were generated by amplifying the respective cDNAs (for primers used, see Supplemental Table S3). Root Growth Assay Arabidopsis seeds were grown on vertical MS medium plates containing different concentrations of BA ranging from 0.01 to 1.0 μm. Dimethyl sulfoxide (DMSO; 0.1%) was included as a vehicle control. The primary root lengths were determined at 10 DAG (Fig. 4), between days 4 and 9 after germination (Fig. 6), or after 4 d of growth in the dark (Fig. 8). Photographs were taken with a digital camera (Nikon Coolpix 8800), and root lengths were determined using the Scion Image program version Beta 4.0.3 (www.scioncorp.com). The number of lateral roots emerging from the epidermis of the primary root was counted with a microscope at 10 DAG. The experiments were performed using three independent replicates and at least 15 seedlings in each replicate. Chlorophyll Retention Assay This assay was performed as described previously (Riefler et al., 2006). Either the sixth or the seventh leaf was detached from 24-d-old in vitro grown seedlings and floated on distilled water supplemented with 0, 0.01, 0.1, 0.5, 1.0, or 5.0 μm BA in 0.1% DMSO in small petri dishes for 10 d at room temperature in the dark. Three replicates of each genotype, each consisting of five leaves, were prepared and two chlorophyll measurements were taken per plate. Chlorophyll was extracted with methanol for 24 h in the dark. The amount of chlorophyll was measured with a spectrophotometer and normalized to fresh weight, and the chlorophyll content was calculated as described (Porra et al., 1989). Ethylene Response Assay Seeds were surface sterilized and placed on vertical plates containing sugar-free MS medium. Different concentrations of ACC (0.1, 1.0, 10, or 30 μM) were included in the medium. The seeds were grown in the dark at room temperature. After 4 d, the hypocotyl lengths were measured using the Scion Image program version Beta 4.0.3 (www.scioncorp.com). The experiment was done in two replicates, each with more than 15 seedlings. The root elongation assay was performed in the same way, but using only one ACC concentration (10 μm). The experiment was done with 15 seedlings per genotype in two replicates. Determination of Seed Size and Weight Determination of seed size and seed weight was carried out as described by Riefler et al. (2006) and Werner et al. (2003), respectively. Seed size of the wild type and ARR1-SRDX overexpressors was determined by measuring the length and width of 60 seeds harvested from two different plants. The volume was estimated by calculating with the formula for a spheroid (volume = 4/3 × π × length × width × depth). Biomass of the seed was weighed using a fine balance LE244S (Sartorius). The weight of one seed was calculated from the weight of pools of 200 seeds. The sample size for each genotype was 10. Seed Germination Assay Seeds of wild-type and 35S:ARR1-SRDX plants used for germination experiments had been harvested and stored under the same conditions. Seed batches of approximately 100 seeds were sown on petri dishes on four layers of filter paper and moistened with 5 mL of distilled water. Seeds were vernalized for 3 d at 4°C in the dark, followed by 6 h at 35°C to alleviate the seeds of hypersensitivity to red light (Fankhauser and Casal, 2004), and for 30 min at 25°C immediately prior to the irradiation. For the different light treatments, seeds were exposed for 5 min to white light (30 μE), red light (660 nm, 6 μE), or far-red light (724 nm, 15 μE) or to a sequential treatment of 5 min of red light followed by 5 min of far-red light. Seeds were stored at room temperature in a dark place for 7 d. Radicle protrusion was employed as the criterion for germination. For microarray experiments, surface-sterilized seedlings of the wild type and line ARR1-S-8 were grown in sterile 0.5× MS liquid medium (1 g L−1 Suc and 0.5 g L−1 MES, pH 5.7) in petri dishes and cultured under the conditions described above. At 5 DAG, the seedlings were treated with either 5 μm BA dissolved in 1.13 mm KCl for 15 or 120 min (BA15 and BA120, respectively) or with 1.13 mm KCl solution for 120 min as a control (BA0). Timing of the treatment was such that the plants were harvested within an interval of 6 to 8 h after the onset of light. The content of two petri dishes was pooled to yield one sample of biological material. Two biological samples were harvested for each experimental condition. RNA was extracted as described previously (Brenner et al., 2005). To reduce the number of false positives due to nonspecific changes in gene expression, we hybridized RNA samples extracted from uninduced wild-type seedlings (BA0) as a reference sample onto an additional set of microarrays. Genes with a significant expression change between this reference sample and the experimental Col-0 BA0 sample were excluded from the genotype comparison. Preparation of the labeled samples for microarray hybridization was performed following the linear amplification protocol (Puskas et al., 2002) with modifications. A first-strand reaction was performed starting with 5 μg of total RNA using SuperScript II reverse transcriptase (Invitrogen). The whole product was used for second-strand synthesis with Escherichia coli DNA polymerase, E. coli DNA ligase, and E. coli RNase H (Invitrogen). After purification with the QiaQuick PCR purification kit (Qiagen), the whole second-strand product was used for in vitro transcription with the MEGAScript High Yield Transcription Kit (Ambion/Applera). The resulting copy RNA was purified with RNeasy mini columns (Qiagen). Five micrograms of the purified copy RNA was used for labeling with the SuperScript II reverse transcriptase (Invitrogen), 2 μg of random nonamers as primers, and 1.5 nmol Cy5-dCTP supplemented with a mixture of 2 nmol dCTP and 10 nmol dDTP. The labeled cDNA was purified with the help of QiaQuick PCR purification columns. We followed the hybridization strategy used in the European Compendium of Arabidopsis Gene Expression project (http://www.cagecompendium.org), employing a Cy3-labeled mixture of oligonucleotides complementary to the secondary primers for gene-specific tag amplification as a common reference sample and Cy5 labeling for the biological samples. Forty picomoles of incorporated Cy5 and 1 pmol Cy3-labeled oligonucleotide reference were dissolved in a mixture of 25% Microarray Hybridization Buffer (Amersham), 50% formamide, and 33.3 ng μL−1 poly(dT35) DNA, applied onto CATMA V2.4 microarrays (ArrayExpress accession no. A-MEXP-274; http://www.ebi.ac.uk/aerep), covered with a coverslip, and incubated in hybridization chambers (Scienion) in a water bath at 42°C for 15 h. The arrays were washed once with 1× SSC, 0.2% SDS for 10 min at 55°C, twice with 0.1× SSC, 0.2% SDS for 10 min at 55°C, and once with 0.1× SSC at 37°C and finally dipped five times into distilled water at room temperature. After drying with an air stream, the microarrays were scanned with a Fuji FLA-5000 scanner at 5-μm resolution and photomultiplier tube gain settings of 93 and 83 for Cy5 and Cy3, respectively. The images were saved in TIFF format. Each biological sample was hybridized onto two microarrays, resulting in a total of four hybridizations per experimental condition. The raw data were submitted to the ArrayExpress database at the European Bioinformatics Institute (www.ebi.ac.uk/aerep) and normalized with a preprocessing pipeline (Allemeersch, 2006) written in R/Bioconductor (Gentleman et al., 2004; RDC Team, 2005). After normalization, general linear models were fitted for each gene (Kerr et al., 2000; Wolfinger et al., 2001). The resulting data were used to generate the interaction plots as well as a table of all expression values, ratios, and P values. FDR-corrected P values (q values) were also included. This table was exported into Microsoft Access, the filtering functions of which were used to identify significantly regulated genes and intersections between groups of genes. A gene was called significantly regulated if it had a q value of ≤0.05, a fold change of ≥2.5, and at least half of the spots above background. The Arabidopsis Genome Initiative locus identifier for ARR1 is At3g16857. The raw data from the microarray experiment are accessible through the ArrayExpress database at the European Bioinformatics Institute (www.ebi.ac.uk/aerep). Supplemental Data The following materials are available in the online version of this article. Supplemental Figure S1. Schematic representation of the ARR1-SRDX fusion protein. Supplemental Figure S2. Phenotype of different 35S:ARR1-SRDX lines. Supplemental Figure S3. Phenotype of the 35S:ARR1-SRDX transgenic plants compared with a triple cytokinin receptor mutant and a cytokinin-deficient plant. Supplemental Table S1. Lists of all significantly regulated genes in the wild type and line ARR1-S-8. Supplemental Table S2. Regulation of ARR1 target genes in 35S:ARR1-SRDX transgenic seedlings. Supplemental Table S3. List of the primers used in this study. We thank Cordula Braatz for skillful technical assistance and Klaus Harter and Virtudes Mira-Rodado for the use of and technical help with the red light chambers. We are grateful to Andrea Ehlert and Wolfgang Dröge-Laser for support with the protoplast assays. We thank also Yves Moreau for help in bioinformatics and Takeshi Mizuno for sending plasmids harboring cDNAs of ARR12, ARR19, and ARR21. The author responsible for distribution of materials integral to the findings presented in this article in accordance with the policy described in the Instructions for Authors (www.plantphysiol.org) is: Thomas Schmülling (tschmue{at}zedat.fu-berlin.de). www.plantphysiol.org/cgi/doi/10.1104/pp.107.115436 ↵1 This work was supported by the Deutsche Forschungsgemeinschaft (grant no. Schm 814/20–2) in the frame of the Arabidopsis Functional Genomics Network. ↵2 These authors contributed equally to the article. ↵3 Present address: Flanders Interuniversity Institute for Biotechnology, MicroArray Facility, B–3000 Leuven, Belgium. ↵[C] Some figures in this article are displayed in color online but in black and white in the print edition. ↵[W] The online version of this article contains Web-only data. Received December 21, 2007. Accepted May 16, 2008. Published May 23, 2008. 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Science 318: 68–69 Nishimura C, Ohashi Y, Sato S, Kato T, Tabata S, Ueguchi C (2004) Histidine kinase homologs that act as cytokinin receptors possess overlapping functions in the regulation of shoot and root growth in Arabidopsis. Plant Cell 16: 1365–1377 Ohta M, Matsui K, Hiratsu K, Shinshi H, Ohme-Takagi M (2001) Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. Plant Cell 13: 1959–1968 Porra RJ, Thompson WA, Kriedemann E (1989) Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b with four different solvents: verification of the concentrations of chlorophyll standards by atomic adsorption spectroscopy. Biochim Biophys Acta 975: 384–394 Puskas LG, Zvara A, Hackler L Jr, Van Hummelen P (2002) RNA amplification results in reproducible microarray data with slight ratio bias. Biotechniques 32: 1330–1340 Rashotte AM, Mason MG, Hutchison CE, Ferreira FJ, Schaller GE, Kieber JJ (2006) A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway. Proc Natl Acad Sci USA 103: 11081–11085 RDC Team (2005) R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna Richmond AE, Lang A (1957) Effect of kinetin on protein content and survival of detached Xanthium leaves. Science 125: 650–651 Riechmann JL, Heard J, Martin G, Reuber L, Jiang CZ, Keddie J, Adam L, Pineda O, Ratcliffe OJ, Samaha RR, et al (2000) Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290: 2105–2110 Riefler M, Novak O, Strnad M, Schmülling T (2006) Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism. Plant Cell 18: 40–54 Romanov GA, Kieber JJ, Schmülling T (2002) A rapid cytokinin response assay in Arabidopsis indicates a role for phospholipase D in cytokinin signalling. FEBS Lett 515: 39–43 Sakai H, Aoyama T, Oka A (2000) Arabidopsis ARR1 and ARR2 response regulators operate as transcriptional activators. Plant J 24: 703–711 Sakai H, Honma T, Aoyama T, Sato S, Kato T, Tabata S, Oka A (2001) ARR1, a transcription factor for genes immediately responsive to cytokinins. Science 294: 1519–1521 Sakakibara H, Takei K, Hirose N (2006) Interactions between nitrogen and cytokinin in the regulation of metabolism and development. Trends Plant Sci 11: 440–448 Shinomura T (1997) Phytochrome regulation of seed germination. J Plant Res 110: 151–161 Sprenger-Haussels M, Weisshaar B (2000) Transactivation properties of parsley proline-rich bZIP transcription factors. Plant J 22: 1–8 Sullivan JA, Deng XW (2003) From seed to seed: the role of photoreceptors in Arabidopsis development. Dev Biol 26: 289–297 Sweere U, Eichenberg K, Lohrmann J, Mira-Rodado V, Baurle I, Kudla J, Nagy F, Schäfer E, Harter K (2001) Interaction of the response regulator ARR4 with phytochrome B in modulating red light signaling. Science 294: 1108–1111 Tajima Y, Imamura A, Kiba T, Amano Y, Yamashino T, Mizuno T (2004) Comparative studies on the type-B response regulators revealing their distinctive properties in the His-to-Asp phosphorelay signal transduction of Arabidopsis thaliana. Plant Cell Physiol 45: 28–39 Taniguchi M, Sasaki N, Tsuge T, Aoyama T, Oka A (2007) ARR1 directly activates cytokinin response genes that encode proteins with diverse regulatory functions. Plant Cell Physiol 48: 263–277 Tiwari SB, Hagen G, Guilfoyle TJ (2004) Aux/IAA proteins contain a potent transcriptional repression domain. Plant Cell 16: 533–543 To JP, Haberer G, Ferreira FJ, Deruere J, Mason MG, Schaller GE, Alonso JM, Ecker JR, Kieber JJ (2004) Type-A Arabidopsis response regulators are partially redundant negative regulators of cytokinin signaling. Plant Cell 16: 658–671 Werner T, Motyka V, Laucou V, Smets R, van Onckelen H, Schmülling T (2003) Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity. Plant Cell 15: 2532–2550 Wolfinger RD, Gibson G, Wolfinger ED, Bennett L, Hamadeh H, Bushel P, Afshari C, Paules RS (2001) Assessing gene significance from cDNA microarray expression data via mixed models. J Comput Biol 8: 625–637 Yang SH, Yu H, Goh CJ (2003) Functional characterisation of a cytokinin oxidase gene DSCKX1 in Dendrobium orchid. Plant Mol Biol 51: 237–248 Yokoyama A, Yamashino T, Amano Y, Tajima Y, Imamura A, Sakakibara H, Mizuno T (2007) Type-B ARR transcription factors, ARR10 and ARR12, are implicated in cytokinin-mediated regulation of protoxylem differentiation in roots of Arabidopsis thaliana. Plant Cell Physiol 48: 84–96 Zimmermann P, Hirsch-Hoffmann M, Hennig L, Gruissem W (2004) GENEVESTIGATOR: Arabidopsis microarray database and analysis toolbox. Plant Physiol 136: 2621–2632 You are going to email the following The Transcriptional Repressor ARR1-SRDX Suppresses Pleiotropic Cytokinin Activities in Arabidopsis Plant Physiology Jul 2008, 147 (3) 1380-1395; DOI: 10.1104/pp.107.115436 An Endogenous Carbon-Sensing Pathway Triggers Increased Auxin Flux and Hypocotyl Elongation Dynamic Changes in the Distribution of Minerals in Relation to Phytic Acid Accumulation during Rice Seed Development Differential Control of Ethylene Responses by GREEN-RIPE and GREEN-RIPE LIKE1 Provides Evidence for Distinct Ethylene Signaling Modules in Tomato Show more DEVELOPMENT AND HORMONE ACTION
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Free Shape Magazine Subscription with signup! Get a Free Subscription to Shape Digital Magazine while this offer is available! No strings attached. Shape Digital subscriptions are fulfilled through Zinio, a free app for Mac, PCs and mobile devices. You must register and log in to Zinio in order to access your digital subscription. SHAPE Magazine offers the latest health, fitness, beauty and fashion news. You'll find monthly strength and cardio workouts, strategies to help you eat right and motivational tips. Click 'Claim now!' below to open this deal in a new window, or 'Next Deal' if you're not interested. Published: May 29, 2015, 6:18 p.m.
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Pasadena, Texas teen, Gabriel 'Gabe' Fernandez 'accidentally' shot dead by his best friend while playing with gun. A 13 year old Texas teen has died after 'accidentally' being shot dead by his 'best friend' while the boy showed a gun at a Pasadena home. Killed was Gabriel 'Gabe' Fernandez – after a bullet fatally struck the boy in the head as a group of boys played with a loaded gun. The identity of the boy who killed Gabe Fernandez has not been released. The boys were said to have thought the gun was unloaded because the clip had been removed. The teen who is believed to have shot the gun lives with his grandparents, who have said they don't own a gun. Police are still investigating the incident, including the origin of the firearm, and no charges have been filed. According to Valdez, her son, Gabriel went over to his friend's house almost every day and walked home from school with that friend every day. 'He loved my son. They were best friends,' the mother told of the boy who shot dead her son. Gabe Fernandez mother: 'I could see where the bullet had exited out of his head'. What started as a normal Saturday, where Gabe and his 15-year-old brother Nick went over to their friend's house, ended in tragedy when Valdez received a 'hysterical' call from her older son about 20 minutes after the boys had left her home. 'He was just hysterical, telling me that 'Gabe's dead, Gabe's dead.' 'What do you mean Gabe's dead?' 'Gabe's dead, he shot him in the head,'' Valdez recalled. 'I ran over and there was people standing outside and little girls crying,' the mother said. 'I could see where the bullet had exited out of his head,' Valdez said. Nick said that a group of teens were in the room with a gun that he said had the clip taken out of it, so they all thought it didn't have any bullets in it. But in reality, many guns hold a bullet in the chamber, even once the clip has been removed. Valdez said her older son just kept saying, 'It was an accident, we didn't know. It was an accident'. Gabe was in the eighth grade at Queens Intermediate School in Pasadena, where he played defense on the Hornets football team. The athlete will be buried in his school football jersey, Valdez said. Another jersey will be signed by his teammates, framed and hung in the locker room, the mother added. Valdez has also gotten comfort from her decision to donate Gabe's organs, so that his death can mean life for others. She's opted for open donation, which means she'll have the ability to meet people who receive organs from her son. In the aftermath of Gabe's death, as his friends stop by, Valdez has said she's taken the opportunity to try to teach them from this horrific experience. 'I keep telling my son's friends who are coming over, "If you see a gun, just leave. If you're hanging out with your friends and they're talking about it and they bring it out just leave… you don't have to be cool. Just walk away,"' she said. In a Facebook post on Tuesday, Valdez shared the details of upcoming funeral arrangements for Gabe. The service will take place on on Saturday at Vazquez Funeral Home, located at 750 Uvalde Road in Houston, from 2pm-9pm. 'All are welcomed to come and wish my baby safe travels to heaven,' she said. Of note, 23 Houston-area children killed by gunfire in the past year, including 3 already in 2019. Seven of the 23 shootings were listed as accidental shootings, or about 30 percent reported the Houston Chronicle. Welcome to a trigger happy brave new America….
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Fidelity... 29/11/2022 Fidelity Charitable launches NFT raffle amid crypto downturn Fidelity Charitable, the nation's largest grantmaker, is getting into NFTs or nonfungible tokens despite a torrent of bad news about cryptocurrency companies FILE - A visitor wearing a face mask walks past artwork displayed at an NFT (non-fungible token)-themed coffee shop at the China International Fair for Trade in Services (CIFTIS) in Beijing, Sept. 3... Twitch Co-Founder's Gaming NFT Marketplace Expands to Polygon Network No, NFTs aren't copyrights NEW YORK --Fidelity Charitable is getting into NFTs, the digital images that are registered on the blockchain, despite a torrent of bad news from the adjacent world of cryptocurrencies. The nation's largest grantmaker is sponsoring a raffle that ends Tuesday, where participants can claim one of the NFTs, which stands for nonfungible token, and 50 will win $1,000 to donate through a donor advised fund at Fidelity. "The reason we're doing this is we really believe there's a whole new generation of givers and philanthropists out there," said Amy Pirozzolo, head of donor engagement for Fidelity Charitable. "We want to be where they are and the channels they use and the formats they use and further encourage their generosity." Around 16% of Americans say they invested in cryptocurrencies, according to a poll from Pew Research Center last year. The demographic most likely to invest were men between the ages of 18 and 29, with 43% reporting that they had invested. The blockchain is the technology that underlies the trading of cryptocurrencies, but it can also record the ownership of digital items like images, videos or Tweets. Fidelity said that 50,000 different wallets, potentially representing that many individuals, have already registered to create an NFT and potentially win the money to donate. Contributions in cryptocurrency to donor advised funds at Fidelity exploded last year, growing from the equivalent of $28 million in 2020 to $331 million in 2021, Fidelity has said. Speaking of the NFT project, Jacob Pruitt, president of Fidelity Charitable, said, "I think it'll be a unique way to engage with next gen investors. It's another way that I think Fidelity is innovating and leaning into a new space." Donor advised funds allow donors to claim a tax credit for charitable donations, but do not require them to give those funds away within any specific timeframe. Organizations that host DAFs, like Fidelity Charitable, also handle more complex donations, which includes exchanging the assets for cash and producing receipts for donors for tax purposes. "Many of the nonprofits either can't take on these assets or they have to hire outside counsel or people to staff to do it," Pirozzolo said. One reason for the jump in cryptocurrency donations is that until recently, their value had appreciated significantly. The cryptocurrency market saw a huge boom in 2021 with the price ofBitcoin, the first cryptocurrency, rising to an all time high of around $68,000 in November last year. But the meltdown of Terra — a stablecoin, or a type of cryptocurrency that tries to peg its value to an asset like the U.S. dollar — in May brought down a series of major cryptocurrency businesses. Then, earlier this month, one of the largest cryptocurrency exchanges, FTX and related entities, suddenly filed for bankruptcy leaving both American and international users unable to access assets they held on the exchange. James Lawrence, co-founder and CEO of Engiven, which facilitates cryptocurrency to nonprofits, including Christian ministries, observed that many people giving cryptocurrencies are making major gifts and that often those happen in the last quarter of the year. That means it's too early to say how the cryptocurrency market's fluctuations may impact donations this year. He said he doesn't see people donating cryptocurrencies as that different from other donors. "They just have a different asset to give and they're going to give the most appreciated asset they can," Lawrence said. Of the more than 1.5 million nonprofits registered with the Internal Revenue Service in the U.S., Lawrence estimated that only four or five thousand could receive cryptocurrency donations directly. "That's a huge market that still doesn't," he said. He also has observed that many giving large donations in cryptocurrency (they facilitated one donation of $10 million in cryptocurrency assets) are the same types of people who give large donations in general, and not necessarily the younger demographics that are more likely to invest in cryptocurrency. "Many of the largest gifts we've processed have been from an older demographic who have a tradition of giving large gifts in multiple asset classes," he said. Another organization, Endaoment, also facilitates cryptocurrency donations to nonprofit organizations as well as hosting pooled funds to benefit certain types of nonprofits. Robbie Heeger, the organization's president and CEO, said besides that fact that nonprofits may receive donations from cryptocurrency donors that they wouldn't otherwise, cryptocurrency proponents are also eager to draw in new users. "This is a leapfrog opportunity for nonprofit organizations to move from paper checks" to cryptocurrency Heeger said. "And the crypto space is very focused on adoption flywheels, on ways to incentivize or encourage the traditional economy to migrate into the crypto economy." He encouraged newcomers to the cryptocurrency space to carefully research projects they might get involved with and to look for ones that have gotten outside audits from professional auditors. Pirozzolo argued that the Fidelity Charitable promotion using NFTs is separate from the cryptocurrency ecosystem. "This is really about the blockchain and having a fun way to celebrate with digital art the generosity of giving," she said. The company is paying for the cost of creating the NFTs, which includes a "gas" fee that pays for the creation and registration of the item, and also said that it has compensated the artists who made the images. People who claim the NFTs will need to sign up for a cryptocurrency wallet that has access to the Polygon blockchain. The Fidelity Charitable NFTs will be hosted on the platform OpenSea. Participants will see the NFT in their wallet when they sign up, but the art itself and the winners of the $1,000 tickets won't be revealed until Giving Tuesday, Nov, 29. https://abcnews.go.com/Business/wireStory/fidelity-charitable-launches-nft-raffle-amid-crypto-downturn-94100732 Interesting NFTs Smile to Shreds, Neon Gwen The First KayPikeFashion Mint Ever. Ever feel so joyful and were grinning so hard you felt you could split in half? That punk rebel yell of glee when you pull of a particularly refined stunt? This is the paint of dreams, fangs and neon. Hellish and hard to pull off. I was able to with this work quietly paint a sweet inner tale of childhood influences, rat fink and autobody shops. All while pretending to paint gwenom for the audience. More on that in bonus material. This is my alternate animation made specifically for crypto art collectors. It will only ever exist in this format. You get the Shiny, unused in media verified image. More on that in the bonus material. Mixed Media: Bio/Digital. Glycerin on 5'9" human skin 10-14 hours Performance art. Shot on Canon EOS RP. 16 + hours Photoshop and DaVinci Resolve. All Works are SFW. Art has been Seen on the front page of Reddit, Featured in the New York Times, Galileo.tv, and multiple other promotions including Twitch.tv, Disney Interactive, RIOT games, WB games, AMD and more! More on how this art is unique and potentially explosive in the NFT world: https://youtu.be/CXbNF2Y6srs ------------------------- The purchase of this NFT Grants the buyer unique bonus material. Physical Mail Bonus Package: A verified physical Art Print. Autographed from the artist in 12x16. Please allow a few weeks for delivery. Digital Bonus Package: This image in .mp4. An "About the Art" Video and an "From the Artist" introduction. A README.txt about the artwork with some personal notes and Links relevant to the artwork. Death Dip #XCOPY #GIF #death #dip #lurking Yo! I'm Kitty #431210. I enjoy glaring at the neighbour's cat, chasing string, and being a nevernude. I put garlic butter on everything. Like, everything: hot dogs, hamburgers—everything! We're so fur-tunate to have found each other! CryptoPunk #6649 The CryptoPunks are 10,000 uniquely generated characters. No two are exactly alike, and each one of them can be officially owned by a single person on the Ethereum blockchain. Originally, they could be claimed for free by anybody with an Ethereum wallet, but all 10,000 were quickly claimed. Now they must be purchased from someone via the marketplace that's also embedded in the blockchain. The Complete MF Collection THE COMPLETE MF COLLECTION by Beeple
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Shortly after the November election, I wrote an article titled, "McCain Beats Romney!" The article focused on initial reports showing that Mitt Romney received fewer votes in 2012 than John McCain received in 2008. Those reports utterly shocked and depressed conservatives. More votes remained out there. Nonetheless, when the final count was tallied, I figured that Romney would still receive fewer votes than McCain. Well, the final count is alas approaching, chronicled by the 2012 National Popular Vote Tracker, maintained by David Wasserman. And it has a rare flicker of good news for Mitt Romney: He has surpassed John McCain's 2008 vote total. The latest near-final tally has Romney with 60.7 million votes, which is higher than McCain's 59.9 million votes. That's the good news for Mitt Romney. The bad news: It's not a lot higher than McCain's total, and certainly not high enough to have overtaken Barack Obama. In fact, Romney's total is only about 1 percent higher than McCain's. Who would have predicted that? Republicans expected far more votes for Mitt Romney in 2012 than McCain got in 2008. Sorry, didn't happen. So, Mitt Romney beats John McCain, but he didn't beat Barack Obama. Barack Obama was reelected with a little under 51 percent of the vote, similar to George W. Bush in his reelection. They both round up to 51 percent. Bush was reelected with 50.7 percent of the vote. Obama's final tally remains in flux. A week-and-a-half ago, it was 50.7 percent. The latest is 50.9 percent. It could go up slightly or down slightly, but not by much. Barack Obama is the first president to be reelected with less popular votes and less Electoral College votes. He got 4.2 million less votes in 2012 than in 2008. Obama also significantly decreased his margin of victory, shifting from a 7.3-percent margin in 2008 to a 3.6-percent margin in 2012. To the contrary, George W. Bush gained a staggering 11.6 million more total votes in 2004 than he had in 2000. Bush also increased his percent-margin from minus 0.5 percent in 2000 to plus 2.4 percent in 2004. And though Obama's Electoral College victory in his reelection was larger than Bush's, it still decreased. Bush's reelection also included his party retaining Congress. In fact, Republicans in 2004 picked up seats in both the House and the Senate, with sizable majorities in both. Obama was unable to come anywhere near that—quite the contrary. In 2012, Democrats retained the Senate but Republicans continued their huge margin in the House. And there's more: Bush was reelected with a larger number of states, winning 30 in 2000 (plus 10) and 31 in 2004 (plus 12). Obama lost states, going from 28 in 2008 (plus 6) to 26 in 2012 (plus 2), which is a bare majority. And should we even mention counties? The county map under Bush was a sea of red, and it remained a sea of red under Obama. For Obama and liberals, this isn't much to brag about, and hardly a sweeping mandate. Overall, it is difficult to claim that Barack Obama's reelection is much more decisive than George W. Bush's. If liberals didn't see a mandate for Bush in 2004, they certainly shouldn't be heralding one for Obama in 2012. In terms of raw numbers, this was not a huge victory for Barack Obama—a fact that ought to give Republicans some hope for 2016, assuming they can turn out notably more people in 2016 than they did in 2012 and 2008. Unfortunately for Republicans, it was just enough of a victory for Barack Obama to continue his "fundamental transformation" of this country.
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The 3 Nicole Lapin Net Worth 2023: Must Read Veteran financial journalist Nicole Lapin currently works as an anchor for CNN, CNBC, and Bloomberg. After being released in 2015, her debut book, "Rich Bitch: A Simple 12-Step Plan for Getting Your Financial Life Together…Finally," immediately shot to the top of the New York Times bestseller list. This article will discuss Nicole Lapin net worth, salary, personal life, dating, and more. What is Nicole Lapin's Net Worth and Salary 2023? Nicole Lapin Overview Why is Nicole Lapin famous? FAQs about Nicole Lapin How tall is Nicole Lapin? How old is Nicole Lapin? Who is Nicole Lapin husband? What is Nicole Lapin's nationality? What is Nicole Lapin net worth? Nicole Lapin is a popular American journalist and author. She has worked as a financial anchor for CNN, CNBC, and Bloomberg Television. As of 2023, Nicole Lapin's net worth is $2 million. She has earned her wealth through her successful career in journalism. Nicole also has her own show on Oprah Winfrey's OWN network. Based on this information, it is safe to assume that Nicole Lapin earns a very comfortable salary. Lapin, a scientist and a former beauty queen, was born and raised in Los Angeles, California. Her relatives are Jews. Lapin's parents forbade her from watching CNN's coverage of the Gulf War because of "the perceived negativity and carnage," but this is when she first developed an interest in journalism. When Lapin was a senior in high school, she worked as the news anchor for the Public-access television cable TV station, gaining her first experience in broadcasting. Career Beginnings In Los Angeles, Lapin was raised. She graduated summa cum laude and was the class valedictorian from Northwestern University's Medill School of Journalism in Evanston, Illinois. She became interested in journalism while working as a cable TV station's news anchor during high school. When Lapin was hired as a correspondent by CBS Stations in South Dakota and Kentucky, her professional career in broadcasting officially began. She started working for KPSP-LP as an investigative "I-Team" reporter around the same time. She also started working for First Business Network as a reporter on the floor of the Chicago Mercantile Exchange. Her wealth started to increase. Lapin joined CNN in 2005 and quickly rose to the position of the network's youngest anchor. She frequently appeared on CNN Headline News and CNN International, covering significant events like the 2009 Michael Jackson memorial service, the 2008 presidential election, the 2007 Virginia Tech shooting, and the 2006 Israel-Hezbollah conflict. She also developed a series of interviews with significant individuals under 30 called "Young People Who Rock." Lapin's work at CNN helped her gain recognition and substantially increased her wealth. She joined CNBC in New York in 2010 to anchor the network's business news program and as a US presenter for its sole global finance show, "Worldwide Exchange." She continued to appear on the program for a year, considerably increasing her popularity and wealth. Later that year, she started co-anchoring "The Kudlow Report," the network's news television show. Along with CNBC, Lapin also contributed to MSNBC and NBC, where she worked as a business and finance correspondent for the morning chat show "Morning Joe" and "The Today Show," the network's morning news and conversation program. Additionally, she has offered corporate news and financial reports to NBC affiliate stations like New York's WNBC and Los Angeles' KNBC. She started working for Bloomberg Television in 2012 as a non-exclusive business anchor and special reporter, solidifying her position as a well-known television personality and financial expert and boosting her financial standing. Lapin frequently appears as a guest on numerous programs, such as "Good Morning America" and "Dr. Oz," where she contributes her knowledge of money matters. She is "The Wendy Williams Show's" correspondent for money-saving tips and "The Insider's" special correspondent covering Hollywood's industry. She is also credited with founding the financial news website Recessionista and the AOL Originals program "I'll Never Forget My First," in which powerful women discuss how they achieved success. The CASH Smartwatch is a wearable gadget that Lapin and her retail partner HSN introduced in 2014. It tracks daily financial transactions. She published "Rich Bitch," her debut book, in the same year, and it quickly shot to the top of the New York Times Bestseller list. All of this increased her wealth, and she is currently writing her second book, "Boss Bitch." She has been the host and sole female judge of the CW Network's business competition program "Hatched" since 2015. Additionally, she has penned a financial column for Redbook Magazine. Lapin is rumored to be dating Michael Rubin, the founder and CEO of GSI Commerce, in her personal life. As a board member of Women in Need and an ambassador for groups like the Starlight Starbright Children's Foundation, Operation Smile, and Points of Light, Nicole is also a committed philanthropist. Prior to becoming a number one best-selling author, Lapin made history as the network's youngest-ever anchor on CNN. She later held the same position at CNBC, where she hosted the network's early morning program, Worldwide Exchange, while reporting on MSNBC and Today's business issues. Nicole's height is 5 feet 4 inches Nicole Lapin age is 54 years old. Lapin has been a vegan since 2002 and a vegetarian since she was a young child. She currently resides in Los Angeles with her fiancé Joe Sanberg. Nicole Lapin is an American journalist, novelist, and entrepreneur. Nicole Lapin has an estimated net worth of $2 million. If you're looking to stabilize your financial life, Nicole Lapin is a great role model to follow. Given her successful career as a financial journalist, she's definitely qualified to offer advice on the subject. Be sure to check out her book, "Rich Bitch: A Simple 12-Step Plan to Get Your Financial Life Together…Be sure to follow Fidlarmusic to learn more of her information." What is Nav Bhatia Net Worth 2023: Overview, Interview Top List 21 Vinessa Shaw Net Worth 2023: Full Info What is Lil Rob Net Worth 2023: Overview, Interview The 10+ What is Robert Wagner'S Net Worth 2023: Must Read The 7 Tj Lavin Net Worth 2023: Full Info
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In this paper, we review the evolution of the field of public health genomics in the United States in the past two decades. Public health genomics focuses on effective and responsible translation of genomic science into population health benefits. We discuss the relationship of the field to the core public health functions and essential services, review its evidentiary foundation, and provide examples of current US public health priorities and applications. We cite examples of publications to illustrate how Genetics in Medicine reflected the evolution of the field. We also reflect on how public-health genomics is contributing to the emergence of "precision public health" with near-term opportunities offered by the US Precision Medicine (AllofUs) Initiative. There is a genetic disorder affecting the immune system so severely that its patients often require protective isolation, hence the disease's nickname: "Bubble Boy Disease." Scientists know this disease as X-linked severe combined immunodeficiency disorder (XSCID). From the St. Jude Children's Research Hospital, scientists conduct the first-ever clinical trial in infants with XSCID to test the effectiveness of the newest gene therapy approach to treating the disease. This 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases. This article describes the hardships of patients living with sickle cell disease, and how it's an example of the broader discrimination experienced by African-Americans in the medical system. This article describles two different DNA-based strategies to treat spinal muscular atrophy (SMA): antisense oligonucleotides and gene therapy. Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein. This article describes a randomized, double-blind, sham-controlled, phase 3 efficacy and safety trial of nusinersen in infants with spinal muscular atrophy. Our genome contains thousands of genes, each of which has to be turned on and off at precisely the right times, or serious dysfunction in our bodies can result. If scientists could learn how to control when a gene is expressed or not, then it would be easier to relieve many human diseases. While there are a number of ways that have been developed and are being tested or such applications, new work is pursuing another avenue for the manipulation of gene expression. A pilot study was completed to determine the feasibility and utility of newborn screening for spinal muscular atrophy (SMA) in New York State.
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Spoon River Journal Canton Veterans Memorial makes progress Despite winter — or perhaps because it has been a mild season so far — the new veterans memorial at Lakeland Park is chugging along. After four re-designs, the $200,000 project features black granite monuments and flags overlooking Lakeland's 440 acres of reclaimed strip mines. It will have a specially-constructed brick terrace with a drainage system to stabilize the memorial bricks and keep maintenance to a minimum. Canton Park District Executive Director Jon Johnson says the foundation work is complete, along with the bases for the three largest flag poles. What he calls scaffolding and the construction folks call "tables and chairs" that hold the bricks in place may be delivered any day now. Meanwhile, the monuments are being lazer-etched, and should be ready by mid-March. "This has been a strange winter, but as soon as it is officially over (whenever that might be) we will begin the process of installing the 'tables and chairs' and then the bricks," Johnson said via email. Fundraising efforts broke the $150,000 mark last week, but the veterans committee could use more help. The 4-by-8-inch bricks sell for $100; 8-by-8-inch bricks for $500. For more information, call Bob Ems at 309-647-7174. Author Terry BiboPosted on February 23, 2012 March 15, 2013 Leave a comment on Canton Veterans Memorial makes progress the final bird word, for now For those of us who yearn to fly somewhere — anywhere — when we spy wild geese, February has been outstanding. According to Lee Albright, manager at Chautauqua National Wildlife Refuge, there were 125,000 snow geese on the South Pool last week. He says the honkers fly out to the fields to feed during the day, which is why random motorists can spot so many. Last Friday, looking up over Farmington, you could barely mark a single V in the raucous scrum overhead. It was more of an overlapping flapping alphabet of Ms and Ws and Js and Os. Just when it crosses your mind that looking up at so many geese may not be advisable, sans umbrella, there's a lone bald eagle cruising along beneath them. Perhaps more importantly, the Chautauqua folks also counted 9,300 mallards on the North Pool, and 650 mallards on the South Pool — about a third more than the 6,800-mallard high last fall. Albright suspects the birds are finding nutsedge seed, one of the main by-products of draining the pool to mimic the natural river cycles. Author Terry BiboPosted on February 22, 2012 March 15, 2013 Leave a comment on the final bird word, for now Living in West Central Illinois, you don't have to go far to see stunning displays of migratory birds. Living in West Central Illinois, you don't have to go far to see stunning displays of migratory birds. You can drive along the Illinois River to wildlife refuges such as Chautauqua or Emiquon. That's no guarantee. There were supposed to be 150,000 snow geese at Chautauqua a week ago, but they were gone by the time people came for the Eagle Day Festival Saturday. Dickson Mounds director Michael Bryant said they tend to head out to local cornfields en masse during the day, then return in the evening. Which means your other alternative may be stepping into the backyard at dawn or dusk. All week, snow geese have been honking through the fog by the thousands around here. This is a photo of some of them, probably Emiquon birds. snow geese from Emiquon Author Terry BiboPosted on February 16, 2012 March 15, 2013 Leave a comment on No place like home Chautauqua eagles Professional eagle watchers had warned that it might be difficult to spot the big birds Saturday. Warm weather was welcome for many reasons, but there's not much ice. Eagles are easier to spot mid-winter when they cluster around open water. Warm weather was welcome for many reasons, but there's not much ice. Eagles are easier to spot mid-winter when they cluster around open water. Still, the Eagle Day Festival was set months in advance. Just in case, there were live bird shows at Dickson Mounds and the new visitors center in Lewistown. Hundreds of people turned out, even though the weather abruptly turned seasonably cold. While they may not have seen dozens of eagles, you could spy a few here and there if you searched a bit. Here are a couple of examples, from the west side of the South Pool at Chautauqua: Author Terry BiboPosted on February 13, 2012 March 15, 2013 Leave a comment on Chautauqua eagles "The Age of Austerity" When the Canton City Council sat down for its daylong strategic planning session last Saturday, George Hall was at the table. Hall is chairman of the Fulton County Board, not a member of the council. But he goes to a lot of public meetings. Hall is chairman of the Fulton County Board, not a member of the council. But he goes to a lot of public meetings as a taxpayer, as well. He has an engineer's knack for obsessively grinding his way through any agenda until he gets to his objective, which grates on a lot of people. On the other hand, he definitely puts in some serious time. This is not meant as a political comment. His predecessor as board chairman, Ed Ketcham, also is running again this spring and addressed the council at the afternoon session. But as a bit of a civic aside, it was interesting to hear what Hall recommends as bedside reading between meetings. He's about halfway through a book called "The Age of Austerity: How Scarcity Will Remake American Politics" by Thomas Byrne Edsall. "All I'm interested in is cost-effective government," Hall says. Considering that Fulton County is hardly the only place where the strain on tax money sparks talk of service cutbacks, it's probably worth checking out. Author Terry BiboPosted on February 8, 2012 March 15, 2013 Leave a comment on "The Age of Austerity" Perhaps it is a coincidence that people have contacted me about blogs lately. They couldn't have known that Spoon River Journal was under consideration as a new blog about what's happening in Fulton and Mason Counties. But reader input has always been one of the things that keeps newspapers interesting. After all, how would we know what's going on if people didn't tell us? Contrary to popular opinion, most reporters don't make this stuff up. We couldn't. Perhaps it is a coincidence that people have contacted me about blogs lately. They couldn't have known that Spoon River Journal was under consideration as a new blog about what's happening in Fulton and Mason Counties. But reader input has always been one of the things that keeps newspapers interesting. After all, how would journalists know what's going on if people didn't tell us? Contrary to popular opinion, most reporters don't make this stuff up. Frequently, we couldn't. Max Latimer of Cuba was writing about the down side of computerized reader feedback, however. "What I had intended to speak about was how comments sections, and perhaps blogs also, include the height of incivility between people that can remain anonymous from each other. Our political arena has been a model of incivility as well as talent contests, reality TV shows, and YouTube videos of teens bullying someone not as hip as their peers think everyone should be," he wrote, while recovering from foot surgery. He said social media is reducing face to face communications. And he notes that just about anyone using the Internet has gotten derogatory emails from anonymous people who would never think of being so rude in person. Point taken. Seen it. Felt it. Didn't like it much. So here's a request. For the most part, this is a place for background and commentary. And if you want to use this space to sound off about things in Spoon River country, welcome. Just bring some proof and/or tell us who you are. Otherwise, buzz off. Author Terry BiboPosted on February 3, 2012 March 15, 2013 Leave a comment on Getting started musings in west central Illinois Walk and talk global change Kid's Fest offers free fun Sounds like bluegrass hit it off At the farmer's market Breakfast of (local) champions ajamcodes.com on Bilbo Baggins: eco-pioneer? doug smith on Kid's Fest offers free fun countrygirl2 on Snider starts new job KathyJean on Just sit on it. Please.
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Anime Boruto News Sasuke will feature in the new Boruto arc Post author By Vansh Gulati No Comments on Sasuke will feature in the new Boruto arc Post Time 12:04 am The Boruto anime adaptation is focusing on fillers. But fans are ready to watch another arc since it is after all, about Naruto's son. The show has yet to strike the audience with an amazing arc, and next one will hopefully be it. That's because the next arc is going to feature our favorite- Sasuke Uchiha and we are just as excited as Boruto Uzumaki about the return. Recently, a fan translator translated episode synopses into English, and it showed how this new arc will begin. "During the time of the Chunin Exams, Sasuke became Boruto's mentor. Since his mentor tends to be away from home, Boruto hasn't been able to receive much training from him. He's gotten tired of waiting on him to come back. But on this occasion, a message arrives at the village from Sasuke, Boruto stealthily eavesdrops on the contents of it and finds out that Sasuke is going to be dropping by for a short visit at a certain location in the Wind Country. In order to receive training from his somehow, Boruto then secretly rushes out of the village. But at the same time, various accidents keep happening one after another, and he isn't readily able to reach his destination. Will Boruto actually be able to meet up with his mentor!?" Looks like an exciting set of events in the new arc. The new arc will begin after Boruto wraps his current mission with Konohamaru about a memory-stealing demon. So, this Sasuke arc will feature in Episode 120 of Boruto – Next Generation. One more possibility is there that Gaara will be shown in this arc. As the synopsis says, Sasuke Uchiha is heading to Wind Country and all the Kages will be there in the sight. So, there is a possibility that Gaara will be there too. After all, Gaara hasn't been seen since the Chunin Exams. Tags Anime, Boruto, Kawaki, Manga, Naruto Uzumaki, Sasuke, Shinki Who is the strongest and weakest Uchiha in Naruto Shippuden? Why is Boruto sad and boring? Will it ever get good? Top 20 Strongest Characters in Naruto Shippuden, Ranked! How To Watch Boruto Anime? Easy Watch Order Guide Boruto Ship Thread: Who will Boruto marry? Will Sasuke Uchiha die in Boruto: Naruto New Generations? Vansh Gulati There is no anime or manga that I'm not aware of. Also the go-to guy for all things Epic in this humble abode. Since I turned 18 and legit - I'm on a journey to enjoy life with a cup of sake!
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Q: How to calculate a fullhouse after dealing 5 cards? In case you are not familiar with a fullhouse, it is when you have XXXYY (three of a kind + a pair). I am not that good calculating odds, but after time I manage to write all the possible combinations: However, I can't translate it to real odds, my questions: * *How can I translate it to odds? *(Since my approach is time consuming, and will be impossible to apply on larger problems) what other alternatives do I have? A: There are $\binom{52}{5}$ ways to choose $5$ cards from $52$. All these ways are equally likely. Now we will count the number of "full house" hands. For a full house, there are $\binom{13}{1}$ ways to choose the kind we have three of. For each of these ways, the actual cards can be chosen in $\binom{4}{3}$ ways. For each way of getting so far, there are $\binom{12}{1}$ ways to choose the kind we have two of, and for each there are $\binom{4}{2}$ ways to choose the actual cards. So our probability is $$\frac{\binom{13}{1}\binom{4}{3}\binom{12}{1}\binom{4}{2}}{\binom{52}{5}}.$$ Remark: We have used binomial coefficients systematically, even when a simpler expression was available. For example, there are clearly $13$ ways to choose the kind we have three of. To calculate the binomial coefficient $\binom{n}{k}$, a reasonably efficient procedure, a not too bad way, when $k$ is not large, is to use $$\binom{n}{k}=\frac{n(n-1)(n-2)\cdots(n-k+1)}{k!}.$$ For $\binom{52}{5}$ the numerator is $(52)(51)(50)(49)(48)$ and the denominator is $(5)(4)(3)(2)(1)$. A similar procedure can be used to find the probabilities of the other standard poker hands. The only place where a mistake is fairly common is the probability of two pairs. For example, to count the number of one pair hands, do this. The kind we have a pair of can be chosen in $\binom{13}{1}$ ways, and for each of these ways the actual cards can be chosen in $\binom{3}{2}$ ways. Now the three kinds we have one each of can be chosen in $\binom{12}{3}$ ways, and the actual cards can be chosen in $\binom{4}{1}\binom{4}{1}\binom{4}{1}$ ways, for a total of $\binom{13}{1}\binom{4}{2}\binom{12}{3} \binom{4}{1}\binom{4}{1}\binom{4}{1}$. A: The tree you have drawn has each state where a random choice occurs as an internal node, each edge weighted by the probability of descending from one state to another, and each final outcome as a leaf. To find the probability of a particular final outcome, you would take the product of the probabilities along the path from the root to that leaf. For instance, the probability of [XYZ] (one of many "bad" outcomes) is $\frac{52}{52}\times\frac{48}{51}\times\frac{44}{50}$. To find the probability of a class of outcome, you would sum these products over all the leaf nodes of that class (e.g., all those labeled "good"). You're right to point out that this isn't the most efficient way to get the result. The key is that if you don't care about the order in which the cards come, you don't have to calculate the probability of each ordered event separately. Instead, you can count the number of "good" hands and divide by the total number of hands (all of which are equally likely) to arrive at the probability you want. In this case, the number of good hands is just $13\times 4 \times 12 \times 6=3744$ (the # ranks for the three-of-a-kind, times the # of ways to choose three suits for the three-of-a-kind, times the # of remaining ranks for the pair, times the # of ways to choose two suits for the pair). The total number of hands is ${{52}\choose{5}}=2598960.$ So the probability of a full house is $$ \frac{3744}{2598960} = 0.001440576... $$ Which method you should use depends on your application, though. For calculating the probability that two cards form a pair, say, the tree method (second card matches the first with probability $3/51=1/17$) is simpler than the counting method (number of pairs is $13\times 6=78$, divided by number of two-card hands ${52\choose{2}}=1326$, gives $78/1326=1/17$).
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The slightly viscous clear oil of Papua/New Guinea Sandalwood presents a uniquely different top/heart-note from other sandalwoods I have encountered. After being placed on the AromaStone the oil gradually begins to transmit its sweet floral top-note to the atmosphere and it very soon joins its floral quality with a deep, rich vanillic/balsamic heart-note. Sitting just beneath this sweet floral-balsamic accord is a dry, precious woods note that deep into the dryout emerges with more distinction in the one to two hour range.
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(SEOUL) September 14, 2005 -- Kia Motors Corporation held the world premiere of its all-new Kia Magentis executive sedan (known as 'Optima' in some markets) at the Frankfurt Motor Show yesterday. Completely redesigned from the ground up, the new Magentis is a modern, high-quality, high-value sedan, which offers customers clean, crisp, and handsome styling; more power; higher performance; better handling and a smoother ride; more space; more luxury; a larger trunk and enhanced fuel economy. Created by Kia design teams in Korea, Germany and the USA, the new Magentis will transform Kia's global fortunes in the important D-segment. The 4,735 mm long new Magentis will provide customers with comfortable, spacious and refined transport in an elegantly understated all-new car. For the first time in the D-Segment, Kia will be offering customers a choice of gasoline and diesel engines. Available only in European Magentis models, Kia's new 2-liter 140 ps CRDi diesel engine features a variable-geometry turbocharger (VGT) and a diesel particle filter (DPF) as standard, for optimum performance and economy, with clean Euro4 compliant emissions. "The new Magentis continues the recent Kia tradition of introducing new models which are attractively styled, comfortably appointed, technically sophisticated and thoroughly modern," said Yong-Hwan Kim, Senior Executive Vice President and COO of Kia Motors Corporation. The new Magentis will be a highly competitive entry into a significant segment of the global market. Depending on the model selected and country, customers can choose from two equipment levels (LX and EX), two of three gasoline engines (2.7, 2.4 and 2.0-liter) and one 2.0-liter diesel engine (in Europe only). A 6-speed M/T and 4-speed A/T are mated to the 2.0-liter diesel, while the 2.0-liter gasoline has a 5-speed M/T and 4-speed A/T. The 2.4-liter powerplant is mated to a 5-speed M/T and 5-speed A/T, while the 2.7-liter engine is offered only with a 5-speed A/T. Taller 1,480 mm (+70 mm), wider 1,805 mm (+15 mm) -- excluding the old model's protruding door handles -- and longer (+5 mm) than the model it replaces, the new Magentis has a longer wheelbase 2,720 mm (+20 mm) and reduced front overhang 935 mm (-25 mm) to create much improved interior packaging, which offers significantly more cabin space, together with a larger 420-liter (SAE) trunk. The new, fully independent McPherson Strut front suspension and Multi-link rear suspension systems are designed to deliver a supple, comfortable ride with agile, responsive handling and good stability under the toughest road and weather conditions. An extensive range of optional equipment is also available. Kia's range-topping Magentis EX model can be ordered with a powerful, responsive, upgraded quad-cam 2.7-liter 188 ps V6 'Mu' petrol engine with VIS (Variable Intake System). An all-new 'Theta' 2.4-liter gasoline engine will also be available in the US and Australia (specifications to be confirmed closer to launch date). Available in both EX and LX Magentis models, the all-new 'Theta' 2.0-liter 144.5 ps petrol engine is an impressively quiet, state-of-the-art four-cylinder powerplant with CVVT. The new 2-liter CRDi diesel engine is also available in both EX and LX Magentis models. This SOHC engine produces 140 ps and 305 Nm of torque from 1,800 to 2,500 rpm (output to be confirmed). All four engines are smooth and powerful, with clean emissions complying with Euro4 standards. Unusually in the D-Segment, all Magentis engines will be available with an automatic transmission. Both petrol and 2-liter diesel (only in Europe) engines can be ordered with a four-speed automatic transmission as an extra-cost option, while the 2.7-liter is mated to a new five-speed automatic gearbox as standard. Fitted with Kia's Sport Mode automatic transmission, these gearboxes offer a choice of fully automatic changes or driver-controlled sequential-manual gear selection. As standard, the 2-liter petrol engine is fitted with a five-speed manual, while the 2-liter diesel engine (only in Europe) is supplied with an all-new, fuel-stretching six-speed manual gearbox. Each New Magentis is available with active and passive safety measures to avoid hazards and protect occupants in real-world accidents. The all-new body shell is manufactured with a large percentage of high-strength steel. ABS with EBD, front and side airbags, front 'active' head restraints and three-point seatbelts for all five occupants, are fitted as standard or as options depending on country. In addition, ESP stability control, reverse parking sensors and curtain airbags are available as options. The new Magentis is manufactured in Korea at Kia's Hwasung assembly plant. It is an exclusively Kia product, independently developed and built on the new MG platform. In future years, the MG platform will also form the foundation for the next generation Kia Carens compact MPV. The new Magentis range is scheduled to reach Kia showrooms in Europe and the general market at the beginning of 2006 and in North America in the Spring 2006 and will be available in nine distinctive exterior colors depending on country. Editors' Note: Specifications and standard equipment may vary depending on country. Kia Motors Corporation (www.kiamotors.com) ? one of the fastest growing automakers in the world -- was founded in 1944 and is Korea's oldest manufacturer of motor vehicles. As part of the Hyundai-Kia Automotive Group, Kia aims to become one of the world's premier automotive brands. Kia's 16 manufacturing and assembly operations in 12 countries produce more than 1.1 million vehicles a year that are sold and serviced through a network of distributors and dealers covering 155 countries. Kia today has over 32,000 employees and annual revenues of $14 billion. It is the major sponsor of the Australian Tennis Open and an official worldwide sponsor of the Davis Cup. Kia Motors Corporation's brand slogan -- "The Power to Surprise" -- represents the company's global commitment to surpassing customer expectations through continuous automotive innovation.
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ویروس کرونا - چگونه این ویروس به سرعت انتقال می یابد دوره: شصت ثانیه با علم / درس: مجموعه ی دوم / درس 5 شصت ثانیه با علم 10 درس | 200 درس درس 1 : مجموعه ی اول درس 2 : مجموعه ی دوم 1. روزهای ۲۳.۵ ساعته 2. رایانه ها تاثیر بتهوون را تایید می کنند 3. ویروس کرونا - کنار آمدن با مبحث فاصله ی اجتماعی 4. ویروس کرونا - پیش بینی راه و آنالیز ایمنی 5. ویروس کرونا - چگونه این ویروس به سرعت انتقال می یابد 6. ویروس کرونا - حیات وحش و بیماری انسانی 7. آیا حیوانات صدای تاریکی را شروع کردند؟ 8. اسپرسو با دانه های بزرگ می تواند بهتر باشد 9. گسترش عفونت بسیار جدی است 10. حقایقی درباره ی موش های خرما 11. سگ های ولگرد به علامت های دست انسان پاسخ می دهند 12. عصب های جنگ یا گریز باعث خاکستری شدن موش ها می شوند 13. یک کبوتر دریایی کنار قایق خود داشته باشید 14. آلودگی انقلاب صنعتی در یخ های تبت 15. ارتفاع جت می تواند بر روی آب و هوا تاثیر گذار باشد 16. استفاده ی انسان های نئاندتال از صدف ها به عنوان ابزار 17. لاک پشت های دریایی جذب پلاستیک های زباله می شوند 18. اسب های آبی پابلو اسکوبار 19. خفاش های بیمار از هم نوعان خود فاصله می گیرند. 20. والابی های مرداب از تریبل ها در زاد و ولد سر تر هستند درس 3 : مجموعه ی سوم درس 4 : مجموعه ی چهارم درس 5 : مجموعه ی پنجم درس 6 : مجموعه ی ششم درس 7 : مجموعه ی هفتم درس 8 : مجموعه ی هشتم درس 9 : مجموعه ی نهم درس 10 : مجموعه ی دهم در این قسمت در مورد ویروس کرونا و راه های انتقال آن صحبت خواهیم کرد. COVID-19 - How and Why the Virus Spreads Quickly This is another in our series of coronavirus episodes of Scientific American's Science Talk, posted on March 23, 2020. I'm Steve Mirsky. In this two-part episode, our contributing editor W. Wayt Gibbs in Washington State—a state hit early and hard by COVID-19—reports on scientists' fast-evolving understanding of this new coronavirus and the probable trajectory of this pandemic. Today, in part one, he focuses on why the new coronavirus is spreading so quickly and is so difficult to control. Check back in tomorrow for part two, when Gibbs looks at computer models that are predicting how long we'll need to shut down large parts of society to prevent hospitals from being overwhelmed. He also looks at how emerging tests for immunity to the virus could pose thorny ethical issues in the months to come. Wayt recorded this episode on March 22. The first voice you hear: Governor Jay Inslee of Washington. JI: "It is not rhetorical or hyperbolic when I say that everyone needs to change their behavior, change the way that we live—temporarily—if we are going to prevent significant loss of life for the people we love in the state of Washington. And when I say everyone, I mean, frankly, everyone. Because we all are potential transmitters of this virus, and we all, to some varying degree, are potential victims of this virus." WWG: That was Governor Jay Inslee, pleading with people in my state on March 20 to stay home and stay away from each other. All around the U.S.—and around the world—governors and mayors and prime ministers are urging, begging—in many places even ordering—their citizens to shelter in place. But it's not easy to resist our hardwired desires to spend time with our friends, to visit our parents and grandparents, to go to work. So here in Washington, like in lots of other places, compliance has been—kind of spotty. Traffic on some of the major highways here—a good proxy for human intermingling—is down only about 20 percent or so from normal. But as scientists learn more about the SARS-CoV-2 virus and the COVID-19 pandemic, it's becoming apparent that we're facing a much more serious situation than most of us thought even a couple weeks ago. Let me give you one example from here in Washington. On March 10, despite stern official warnings not to gather in groups, 56 people met for an event in Skagit County. All of them were apparently healthy at the time. But 10 days later, 43 of those 56 people have either been confirmed to have COVID-19 or are showing symptoms of the disease. Experts suspect that one or more people in the group was a so-called "supershedder," someone who has yet to show symptoms but is transmitting lots of infectious virus. In this two-part episode, we'll look at several new research studies and new tests announced this week that may help answer four crucial questions. Question 1: Can you catch this disease from someone who isn't in the same room as you? Question 2: Can you catch it from somebody who isn't sick—and is there a way to test for that? Question 3: What combination of shutdowns and closures will do the most to minimize the number of people who die from the pandemic? And how long will those tough restrictions need to continue? And question 4: How will each of us know when we're immune and no longer need to worry about catching COVID-19 or giving it to someone else? And what will we do with that information once we have it? Let's start with that first question: Do you have to come in contact with someone who has the virus—or with droplets they are spraying from a cough or a sneeze—to catch it? Well, that's almost certainly the easiest way to get it. So keeping your distance from others greatly reduces your risk of infection. But in a study out this week in the New England Journal of Medicine, researchers at a Montana biohazard lab run by the National Institutes of Health confirmed what many experts had feared: this coronavirus can also be infectious outside of a living body—in some cases for days. The other night I watched the 2011 movie Contagion, which certainly has some eerie parallels to the present. There's a scene where Kate Winslet's character, a CDC disease investigator, explains why that kind of durability is so troubling in a virus. KW: "So at this point I think we have to believe this is respiratory—maybe fomites, too." "What's that, fomites?" KW: "It refers to transmission from surfaces. The average person touches their face 2- or 3,000 times a day—three to five times every waking minute. In between, we're touching doorknobs, water fountains, elevator buttons and each other. Those things become fomites." WWG: The NIH researchers tested whether the SARS-CoV-2 virus can spread via fomites—which, by the way, is how you actually pronounce it. They sprayed infectious droplets onto cardboard, stainless steel and plastic. Then they checked the spatter as time passed to see how quickly the viral particles dried out and fell apart. On cardboard, it took a good four hours before the amount of live virus started to fall significantly, and the surface remained quite infectious eight hours later. So when an Amazon box appeared on my front porch a couple days ago, I was glad to see that the delivery man was wearing gloves. But after I opened the box, I still went to the sink and washed my hands. On stainless steel—think railings, shopping carts, gas pumps, jungle gyms—the coronavirus remained infectious for more than a day. And on plastic—so, our pens, our credit cards, our keyboards and keypads—it stayed viable for two to three days. Here in the Seattle area, store managers and bus operators have been wiping down surfaces more frequently and making disinfecting wipes available at the door for customers to use. We now know that should be standard practice everywhere. Inside that box I received from Amazon was a set of white cotton gloves that I had ordered for me and my family to wear when we go out. Tests have shown that a standard face mask really doesn't protect you from catching this virus because so much of the air you inhale leaks in around the edges rather than going through the filter. Wearing a mask is a nice courtesy, though, if you're going to be around others who may be vulnerable. But a pulmonary surgeon advised me to wear cotton gloves, as they do at his hospital, because the natural fibers trap the virus and it dries out and becomes inactive. Also, I find that wearing gloves helps me remember to avoid touching my face. So we can get infected from people we never even see—from the fomites they leave behind. But now let's turn to that second question: Can you catch COVID-19 from someone who hasn't tested positive or even from someone who may feel perfectly healthy? Studies seem to confirm that the answer is yes. In a paper that appeared on March 16 in the journal Science, an international group of researchers analyzed data on the outbreak in China in January. They concluded that only 14 percent of COVID-19 infections were documented, meaning that 86 percent—that's six out of seven cases—never showed up in the statistics as a confirmed case. Here's what Jeffrey Shaman of Columbia University, one of the authors of that paper, said about that in a news briefing last week: JS: "These undocumented infections were about half as infectious per person as a documented case who has more severe symptoms and may be shedding more. Because, however, there are many more of these undocumented cases, it's the undocumented infections that are driving the spread and growth of the outbreak." Shaman says these undocumented cases are mostly quite mild. JS: "And so most people may not recognize that they may think they have another cold, or they may not even really recognize that they're ill. If you were to project that number globally, given that we have 150,000 confirmed cases, it says that we're approaching close to a million infections globally. Generally, you're looking at about an order of magnitude more cases than have been confirmed." WWG: Of course, every day the count of confirmed cases rises. But the idea is that if you take the count today and multiply by seven, that's a more realistic estimate of the number of infections to date. So who is transmitting the virus? Obviously people who are very sick and have tested positive. Plus maybe seven times more people, many of them young, who have caught it but feel well enough that they wouldn't think to get tested or to self-quarantine. And then there's a third group: the fast increasing numbers of people who are infected and who—five or 10 days from now—will fall ill and become a confirmed case but who feel perfectly fine at the moment. In a preprint article published on March 18, researchers with the World Health Organization studied 94 COVID-19 patients in Guangzhou, China, to determine when they became infectious—and when they stopped shedding the virus. The scientists collected throat swabs from the patients as soon as they began showing symptoms and then tested them again every day for the following month. They saw a lot of variation from patient to patient. But overall, the patients tended to become less infectious as their symptoms progressed. Through some calculations, the scientists concluded that these coronavirus patients shed the most virus, and were probably most infectious to others, up to two days before they started feeling ill. So these are people like Senator Rand Paul of Kentucky, who, we learned on March 22, has tested positive for COVID-19 even though he isn't yet feeling any symptoms. These WHO researchers estimate that around half of the people who caught this virus in Guangzhou got it from someone who was still feeling healthy at the time. And other studies from China have documented cases where patients have fully recovered from COVID-19 but continued to test positive for the virus for more than a week after their symptoms disappeared. This phenomenon of presymptomatic and postsymptomatic transmission really complicates efforts to contain this virus, in particular because it will be a long time before we have enough coronavirus tests to check people who aren't yet showing symptoms. In a move to help ease shortages of coronavirus tests, the U.S. Food and Drug Administration last week gave emergency authorization to hospitals and labs to use a new automated test for COVID-19 that can detect infections in minutes rather than days. Cepheid, a biotech company in California, says it will start shipping the test kits this week. The Cepheid test performs essentially the same real-time PCR process that existing tests do, just much faster, says Cepheid's chief medical officer David Persing: DP: "So what we've developed is a reference-lab-quality test that can be run at the point of care in about 45 minutes or less. You take a sample, put it into this new cartridge that we've developed and, about 45 minutes later, you'll have the result. And that test can be run at the hospital as patients are being admitted. So the results are available much more quickly. And that means that those results will play into how those patients are managed: Who gets respiratory isolation. Who needs antibiotics? Who doesn't need antibiotics? Those kinds of decisions can be made in real time." Persing says that while the test could be used for screening in the community—and may be sensitive enough to detect presymptomatic supershedders—initially it will be available only for hospitals to use on their patients and health care workers. DP: "We think this will be a very important tool in being able to get rapid, actionable results to let patients know if they're carriers even if they're asymptomatic—to quarantine—and to know that they're being quarantined for a reason, not because they may have hay fever or some other cause. But really give them a reason for quarantine." Faster, easier tests should help us get a better handle on the true extent of this pandemic. But these tests aren't perfect. A number of studies, including one done by scientists at Wuhan University in February, have found that these RT-PCR tests we're relying on today aren't sensitive enough to reliably catch the infection in its early stages. So a negative test result is no guarantee that you're not carrying the virus. Nor does it tell you whether or not you are immune to the disease. But new tests for immunity are coming. These characteristics of the new coronavirus—its ability to lie in wait on surfaces and to spread easily among people who feel fine or well enough—that is what make this virus so contagious and hard to stop, as Elizabeth Halloran of the Fred Hutchinson Cancer Research Center explained at a news briefing last week: EH: "The basic reproductive number—that is, the average number of people that an average person infects at the beginning—is estimated to be about 2.5. And there are actually estimates that are higher. "That's before, of course, all this behavioral reduction and social distancing, which would reduce it. But it's going to be difficult, even if it does go down somewhat seasonally in the summer, to bring that down necessarily below one." And until we can drag that reproductive number from 2.5 or so down to less than one, the pandemic will continue to accelerate. In part two of this episode, we'll look at how computer models of the pandemic are predicting when we'll be able to emerge from our state of sequestration and start hanging out with each other again. Also in part 2, I'll update you on antibody tests for immunity to the virus that are now emerging from research labs. And we'll look at some tough ethical questions that society may confront as it uses this technology. Until then, for Scientific American's Science Talk, I'm Wayt Gibbs. تا کنون فردی در بازسازی این صفحه مشارکت نداشته است.
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Market Place by Jasons is a leading high-end supermarket in Hong Kong with an extensive range of quality fresh produce, gourmet groceries, international wine selections, household items, branded health and beauty products together with a pleasant shopping environment and friendly service. AIA Vitality members can enjoy 20% discount off Healthy Food (Fresh fruit and vegetables) at all Market Place by Jasons in Hong Kong when they purchased the Fresh Fruit and Vegetables voucher(s) through the AIA Vitality website. Plus, earn AIA Vitality Points as you purchase the voucher(s). You must complete your online AIA Vitality Nutrition Assessment in the last 12 months before you can purchase the Fresh Fruit and Vegetables voucher(s). You get 20% discount off all Fresh Fruit and Vegetables vouchers purchased through AIA Vitality. The voucher can be used to buy fresh fruit and vegetables at any Market Place by Jasons in Hong Kong. by purchase Fresh Fruit and Vegetables vouchers. Where do I buy the Fresh Fruit and Vegetables voucher? The voucher(s) can only be purchased on the Fresh Fruit and Vegetables Gift Voucher ordering page, accessed through the AIA Vitality website. There is a minimum order of two vouchers (value of HK$50 each) for each transaction. Voucher purchases are capped at HK$1,000 per calendar month, i.e. you may buy a maximum of 20 vouchers each month. The voucher limit will not be carried forward to the next month as it is reset on the first day of each calendar month. What can I buy with the Fresh Fruit and Vegetables voucher? You may buy fresh fruit and vegetables items at any Market Place by Jasons locations in Hong Kong. The full value of the voucher will be redeemed at check-out and no change will be given. Please note that voucher may only be used by the AIA Vitality member and are non-transferable. How many AIA Vitality Points do I earn? AIA Vitality members will earn 20 AIA Vitality Points for every voucher (worth HK$50) purchased. AIA Vitality Points earned from fresh fruit and vegetables spending are capped at 400 points a month and an overall cap of 4,800 AIA Vitality Points in each membership year. AIA Vitality Points will not be awarded to a member who has an inactive AIA Vitality membership. How do I get my voucher(s)? Your vouchers will be delivered to you by post. Please verify your mailing address under "Get Started" section before you proceed to the voucher ordering page. This is to ensure that your voucher(s) will be sent to the correct address. You will receive a confirmation email once your payment has been processed.
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This concise introduction to the Gettysburg campaign relates fascinating facts about all aspects of the battle and its participants. This concise introduction to the Gettysburg campaign relates fascinating facts about all aspects of the battle and its participants. Revised and expanded for the 150th anniversary of the battle, it explains why the battle began, how it was fought, who was in command, what the soldiers experienced, and how the nation, the armies, and the town of Gettysburg dealt with the aftermath of the fighting -- all in a compact, fun-to-read format.
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Uretra.it > Medici > HuRGUST > Guido Barbagli – Curriculum Vitae Guido Barbagli – Curriculum Vitae Guido Vincenzo Silvio Barbagli was born on January 22 1950 in Pieve Santo Stefano, Arezzo, Italy. In 1968, he graduated from a Classical Studies High School. He attended Medical School in Florence and discussed his thesis on "The role of inflammatory changes of the prostate in the male sterility". In October 1982, he obtained a Postgraduate Degree in Urology from the Urology Postgraduate Department of the University of Florence, Italy, receiving the highest marks in his class cum laude. From 1978 to 1989: Volunteer In-house Doctor at the Urologic Clinic of the University of Florence, Italy. From 1989 to 1990: Assistant Doctor at the Department of Urology, University of Florence, Italy. From 1990 to 1999: Fellow Associate Doctor in the Department of Urology, University of Florence, Italy, with voluntarily resigning from service on February 15, 1999. Currently, Guido Barbagli is the Director of the Center for Reconstructive Urethral Surgery, which he founded in 1999 in Arezzo, Italy. Scientific articles: ninety-one publications edited and printed in international scientific journals. Books: four books on Reconstructive Urethral Surgery. Chapters in books: "Repair of Bulbar Urethra Using the Barbagli Technique", in the book "Reconstructive Urethral Surgery". Authors: F. Schreiter and G.H. Jordan, Editor: Springer Medizin Verlag, Heidelberg, 2006, chapter 22, pp182-187. "Buccal Mucosal Graft Urethroplasty", in the book "Urethral Reconstructive Surgery". Author: S.B. Brandes, Editor: Humana Press, USA, 2008, chapter 11, pp119-135. "Anterior Urethral Reconstruction using Dorsal Graft", in the book "Reconstructive Urologic Surgery". Authors: D. Montague, I. Gill, K. Angermeier, J.H. Ross, Editor: Informa Healthcare, UK, London, 2008, chapter 56, pp466-472. Dr. Barbagli is a member of the following scientific societies: Société Internationale d'Urologie (SIU) American Urological Association (AUA) Società Italiana di Urologia (SIU) Società Italiana di Andrologia (SIA) Dr. Barbagli acts as a referee for the most important scientific journals. Dr. Barbagli has been a participant and invited keynote speaker to numerous National and International Meetings and Congresses. Dr. Barbagli has been appointed President of "THE SOCIETY OF GENITOURINARY RECONSTRUCTIVE SURGEONS (GURS)", for the period 2008 – 2009. Currently, Dr. Barbagli holds a position as a limited-term Professor for the Postgraduate School of Urology (Director Prof. Patrizio Rigatti) at the Department of Medicine and Surgery, University Vita Salute-San Raffaele, Milan, Italy. For more information please contact info@urethralcenter.it
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A super name for a realtor, home development, home services, a nanny, domestic services, home repairs, a spa or vacation destination, a summer camp and more! a Real Estate Services business, a Home Decor business, a Home Improvement business and more! Other Names Based On "fav"
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92,687
Silver mirror sunglasses can be expensive or difficult to find, but now you can have these classic vintage treasures at an affordable price. There is a distinctive, almost mysterious quality to having mirrored lenses, they hide your eyes. You can see them, but they cant see you. That, combined with the classic style, makes for an eye-catching piece of eyewear. You'll look great wearing them, and you can feel good about yourself knowing it. The frame is yellow and the mirrored lenses provide 100 percent UV400 protection. Measures 52mm tall, 146mm long, and 139mm wide. These are more neon green-yellow''ish than a bright yellow - a touch off from the picture. Otherwise, strong build and quality.
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package org.apache.nifi.processors.aws.dynamodb; import java.io.ByteArrayOutputStream; import java.io.IOException; import java.util.Arrays; import java.util.Collections; import java.util.HashMap; import java.util.List; import java.util.Map; import org.apache.commons.io.IOUtils; import org.apache.commons.lang3.StringUtils; import org.apache.nifi.annotation.behavior.InputRequirement; import org.apache.nifi.annotation.behavior.ReadsAttribute; import org.apache.nifi.annotation.behavior.ReadsAttributes; import org.apache.nifi.annotation.behavior.InputRequirement.Requirement; import org.apache.nifi.annotation.behavior.SupportsBatching; import org.apache.nifi.annotation.behavior.WritesAttribute; import org.apache.nifi.annotation.behavior.WritesAttributes; import org.apache.nifi.annotation.documentation.CapabilityDescription; import org.apache.nifi.annotation.documentation.SeeAlso; import org.apache.nifi.annotation.documentation.Tags; import org.apache.nifi.components.PropertyDescriptor; import org.apache.nifi.flowfile.FlowFile; import org.apache.nifi.processor.ProcessContext; import org.apache.nifi.processor.ProcessSession; import com.amazonaws.AmazonClientException; import com.amazonaws.AmazonServiceException; import com.amazonaws.services.dynamodbv2.document.BatchWriteItemOutcome; import com.amazonaws.services.dynamodbv2.document.DynamoDB; import com.amazonaws.services.dynamodbv2.document.Item; import com.amazonaws.services.dynamodbv2.document.TableWriteItems; import com.amazonaws.services.dynamodbv2.model.AttributeValue; import com.amazonaws.services.dynamodbv2.model.WriteRequest; @SupportsBatching @SeeAlso({DeleteDynamoDB.class, GetDynamoDB.class}) @InputRequirement(Requirement.INPUT_REQUIRED) @Tags({"Amazon", "DynamoDB", "AWS", "Put", "Insert"}) @CapabilityDescription("Puts a document from DynamoDB based on hash and range key. The table can have either hash and range or hash key alone." + " Currently the keys supported are string and number and value can be json document. " + "In case of hash and range keys both key are required for the operation." + " The FlowFile content must be JSON. FlowFile content is mapped to the specified Json Document attribute in the DynamoDB item.") @WritesAttributes({ @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_KEY_ERROR_UNPROCESSED, description = "Dynamo db unprocessed keys"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_RANGE_KEY_VALUE_ERROR, description = "Dynamod db range key error"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_KEY_ERROR_NOT_FOUND, description = "Dynamo db key not found"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_EXCEPTION_MESSAGE, description = "Dynamo db exception message"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_CODE, description = "Dynamo db error code"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_MESSAGE, description = "Dynamo db error message"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_TYPE, description = "Dynamo db error type"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_SERVICE, description = "Dynamo db error service"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_RETRYABLE, description = "Dynamo db error is retryable"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_REQUEST_ID, description = "Dynamo db error request id"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ERROR_STATUS_CODE, description = "Dynamo db error status code"), @WritesAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ITEM_IO_ERROR, description = "IO exception message on creating item") }) @ReadsAttributes({ @ReadsAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ITEM_HASH_KEY_VALUE, description = "Items hash key value"), @ReadsAttribute(attribute = AbstractDynamoDBProcessor.DYNAMODB_ITEM_RANGE_KEY_VALUE, description = "Items range key value") }) public class PutDynamoDB extends AbstractWriteDynamoDBProcessor { public static final List<PropertyDescriptor> properties = Collections.unmodifiableList( Arrays.asList(TABLE, HASH_KEY_NAME, RANGE_KEY_NAME, HASH_KEY_VALUE, RANGE_KEY_VALUE, HASH_KEY_VALUE_TYPE, RANGE_KEY_VALUE_TYPE, JSON_DOCUMENT, DOCUMENT_CHARSET, BATCH_SIZE, REGION, ACCESS_KEY, SECRET_KEY, CREDENTIALS_FILE, AWS_CREDENTIALS_PROVIDER_SERVICE, TIMEOUT, SSL_CONTEXT_SERVICE)); /** * Dyamodb max item size limit 400 kb */ public static final int DYNAMODB_MAX_ITEM_SIZE = 400 * 1024; @Override protected List<PropertyDescriptor> getSupportedPropertyDescriptors() { return properties; } @Override public void onTrigger(final ProcessContext context, final ProcessSession session) { List<FlowFile> flowFiles = session.get(context.getProperty(BATCH_SIZE).asInteger()); if (flowFiles == null || flowFiles.size() == 0) { return; } Map<ItemKeys, FlowFile> keysToFlowFileMap = new HashMap<>(); final String table = context.getProperty(TABLE).getValue(); final String hashKeyName = context.getProperty(HASH_KEY_NAME).getValue(); final String hashKeyValueType = context.getProperty(HASH_KEY_VALUE_TYPE).getValue(); final String rangeKeyName = context.getProperty(RANGE_KEY_NAME).getValue(); final String rangeKeyValueType = context.getProperty(RANGE_KEY_VALUE_TYPE).getValue(); final String jsonDocument = context.getProperty(JSON_DOCUMENT).getValue(); final String charset = context.getProperty(DOCUMENT_CHARSET).getValue(); TableWriteItems tableWriteItems = new TableWriteItems(table); for (FlowFile flowFile : flowFiles) { final Object hashKeyValue = getValue(context, HASH_KEY_VALUE_TYPE, HASH_KEY_VALUE, flowFile); final Object rangeKeyValue = getValue(context, RANGE_KEY_VALUE_TYPE, RANGE_KEY_VALUE, flowFile); if (!isHashKeyValueConsistent(hashKeyName, hashKeyValue, session, flowFile)) { continue; } if (!isRangeKeyValueConsistent(rangeKeyName, rangeKeyValue, session, flowFile)) { continue; } if (!isDataValid(flowFile, jsonDocument)) { flowFile = session.putAttribute(flowFile, AWS_DYNAMO_DB_ITEM_SIZE_ERROR, "Max size of item + attribute should be 400kb but was " + flowFile.getSize() + jsonDocument.length()); session.transfer(flowFile, REL_FAILURE); continue; } ByteArrayOutputStream baos = new ByteArrayOutputStream(); session.exportTo(flowFile, baos); try { if (rangeKeyValue == null || StringUtils.isBlank(rangeKeyValue.toString())) { tableWriteItems.addItemToPut(new Item().withKeyComponent(hashKeyName, hashKeyValue) .withJSON(jsonDocument, IOUtils.toString(baos.toByteArray(), charset))); } else { tableWriteItems.addItemToPut(new Item().withKeyComponent(hashKeyName, hashKeyValue) .withKeyComponent(rangeKeyName, rangeKeyValue) .withJSON(jsonDocument, IOUtils.toString(baos.toByteArray(), charset))); } } catch (IOException ioe) { getLogger().error("IOException while creating put item : " + ioe.getMessage()); flowFile = session.putAttribute(flowFile, DYNAMODB_ITEM_IO_ERROR, ioe.getMessage()); session.transfer(flowFile, REL_FAILURE); } keysToFlowFileMap.put(new ItemKeys(hashKeyValue, rangeKeyValue), flowFile); } if (keysToFlowFileMap.isEmpty()) { return; } final DynamoDB dynamoDB = getDynamoDB(); try { BatchWriteItemOutcome outcome = dynamoDB.batchWriteItem(tableWriteItems); handleUnprocessedItems(session, keysToFlowFileMap, table, hashKeyName, hashKeyValueType, rangeKeyName, rangeKeyValueType, outcome); // Handle any remaining flowfiles for (FlowFile flowFile : keysToFlowFileMap.values()) { getLogger().debug("Successful posted items to dynamodb : " + table); session.transfer(flowFile, REL_SUCCESS); } } catch (AmazonServiceException exception) { getLogger().error("Could not process flowFiles due to service exception : " + exception.getMessage()); List<FlowFile> failedFlowFiles = processServiceException(session, flowFiles, exception); session.transfer(failedFlowFiles, REL_FAILURE); } catch (AmazonClientException exception) { getLogger().error("Could not process flowFiles due to client exception : " + exception.getMessage()); List<FlowFile> failedFlowFiles = processClientException(session, flowFiles, exception); session.transfer(failedFlowFiles, REL_FAILURE); } catch (Exception exception) { getLogger().error("Could not process flowFiles due to exception : " + exception.getMessage()); List<FlowFile> failedFlowFiles = processException(session, flowFiles, exception); session.transfer(failedFlowFiles, REL_FAILURE); } } private boolean isDataValid(FlowFile flowFile, String jsonDocument) { return (flowFile.getSize() + jsonDocument.length()) < DYNAMODB_MAX_ITEM_SIZE; } /** * {@inheritDoc} */ protected Map<String, AttributeValue> getRequestItem(WriteRequest writeRequest) { return writeRequest.getPutRequest().getItem(); } }
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Black Friday is still the hot topic in the poker world, but the crew finds some time to discuss lighter topics including Phil Galfond's slide. The hosts are then joined by Andrew "BalugaWhale" Seidman, who offers his opinions about the current state of online poker in the United States. The PokerNews crew is at Mohegan Sun for the NAPT, and they had a chance to sit and talk about the decline in poker, Erik Seidel, Vanessa Selbst, and the upcoming Party Poker Big Game. They're then joined by Jason Mercier and Dan O'Brien to discuss a variety of topics including the Miami Heat, life coaches and six-bet shoving light. It's a slow news week, but the crew is back to discuss getting Fricke Rolled, Full Tilt Poker's venture with Station Casinos and, what everyone is dreading, taxes. They're then joined by Barry Greenstein who shares some insightful information about Wynn/PokerStars, High Stakes Poker and of course, beautiful Asian women.
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31,414
BizQuest has more Chincoteague Island, VA business for sale listings than any other source. Whether you are looking to buy a Chincoteague Island, VA business for sale or sell your Chincoteague Island, VA business, BizQuest is the Internet's leading Chincoteague Island, VA business for sale marketplace. Refine your search by location, industry or asking price using the filters below. The median income in Accomack County is between $15K and $25K, and the most common level of education is high school. The median age of a Accomack County resident is between 40 and 49 years old. Be the first to know when new Businesses for Sale in Chincoteague Island, VA are posted on BizQuest.
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collecting priceless relics of human history from ancient civilizations across the world. The treasures of Indus Valley, Mesopotamia, Ancient Tibet, middle East, China and Ancient Roman Empire. Mythical dZi beads said to have been made by the gods. Handcrafted art objects made by the descendants of Buddha in the ancient traditions of his time. ..All these and more have been collected by him in a quest spanning over 30 years. Indra has worked hard to keep time still &preserve the glorious traditions of antiquity.He brings his priceless collection of beads, jewels, art and antiquities once again to Tucson.
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In response to strong public input and a shortage of parks and trails in Loudoun County, a committee of Coalition members proposes Emerald Ribbons, a countywide interconnected system of linear parks and trails. Such a widely accessible network, built along streams and other natural corridors, can create an asset of enormous benefit to Loudoun County, raising property values, improving health and quality of life, attracting business investment and providing protection for natural areas and drinking water sources. The proposed countywide system would link east and west, north and south through a trails network that would allow residents and visitors to enjoy Loudoun's natural beauty.
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Drivin' N' Cryin' to release their first record in twelve years "GREAT AMERICAN BUBBLE FACTORY," September 29TH By CMP on July 21, 2009 in News "Crunching hard rock is the drivin' part, brittle countryish balladry the cryin', with the two linked by a heavy dose of Led Zeppelinphilia. If Paul Westerberg had grown up worshiping Angus Young instead of Alex Chilton, the Replacements might sound something like this youthful Atlanta trio." Rolling Stone review of Whisper Tames the Lion ATLANTA, GA – Drivin' N' Cryin' will put out their first record in twelve years. Great American Bubble Factory will be released on September 29, 2009 on Vintage Earth Music with marketing and distribution provided by Thirty Tigers/RED. "This record is the perfect crescendo to a long twenty-plus year career of the band. I think we've found the true essence of what we started to build back in 1985," says Kevn Kinney. Drivin' N' Cryin' originally started recording demos for this album on September 10, 2001. After 9/11 the band abandoned the sessions after deciding the time wasn't right for their stories of blue-collar optimism. They returned to Sonica Studios in Atlanta earlier this year where the band produced the album in collaboration with Anton Fier, who produced their 1987 album Whisper Tames the Lion and James Barber, their ex-manager-turned-producer. This record moves from the "Midwestern Blues" to the Flannery O'Connor South of "This Town" to the industrial grind of "Detroit City" to the optimistic anthem (and Dictators cover) "I Stand Tall" to the genuine pining for home in "I See Georgia." The current DNC line up is: Kevn Kinney (guitar & vocals), Tim Nielsen (bass, mandolin & backing vocals), Mac Carter (guitar), Dave V. Johnson (drums, percussion & backing vocals). The band will be on tour throughout the fall, tour dates will be announced soon. You can hear a preview of "Detroit City" on the band's myspace page: http://www.myspace.com/drivinncryin album, american, cryin, drivin n cryin, fall tour dates, flannery o connor, Great, kevn kinney, Paul Westerberg, Whisper J.B. Beverley and the Wayward Drifters "Watch America Roll By" Helltrain SAM BUSH TO RECEIVE LIFETIME ACHIEVEMENT FOR INSTRUMENTALIS
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89,594
Sproutology We also serve who only stand and wait; Prefab Sprout relics and rarities B Side Guide Buy The T Shirt SproutMash Karen Schoemer, Creem Magazine – October 1988 I gotta thank Prefab Sprout for one thing. I was in this record store in downtown Manhattan early one Friday evening looking for a copy of their second album, Two Wheels Good. because I had promised the editor I'd do a story on the band and I didn't own any of their records. The store didn't have it. so I headed up towards Tower Records and on my way decided to buzz by the building where Keith Richards lives, as I always do when I'm in the neighborhood, just in case. I had already passed the building. It's got a really nice foyer – when out of the corner of my eye I saw a small commotion around the doorway. Fuckin' a: it was Keith. I nealy shat. I ran back and pressed my nose against the foyer glass: he was boppin' across the floor with a lopey, rolling gait, wearing a black suit and big purple sunglasses. and his hair was pushed up in every direction just like in all those pictures. He was with his wife Patti. They got on the elevator. The elevator door closed. That was it. Bye. I found my way into Tower shortly thereafter. They didn't stock the Prefab Sprout record either. ll didn't matter. The other thing I have to thank Prefab Sprout for is that Paddy McAloon, their singer and songwriter, is one hell of a nice guy. at least to interview. I met him uptown at the offices of his record company; he wore a voluminous white suit and tortoise-shell specs. and he was smoking a cigar. In fact, the first thing he did was autograph the copy of their new record. From Langley Park to Memphis. which the record company so graciously provided for a friend of mine whose birthday was approaching and who was a huge Sprout fan. Paddy explains that he likes doing things like that and as a matter of fact. his brother Martin. who serves as Prefab Sprout's bassist. recently married and received as a wedding gift the sheet music for "Alfie." autographed by Burt Bachrach. Not only that. he continues. when they were in the studio recording a song called "Nightingales" for the new album. Stevie Wonder joined the band to add a harmonica solo onto the track. "My brother said to Stevie Wonder. 'Can I play Alfie with you?' Stevie said. 'Okay.' and they played a duet!" Paddy recalls. "So his life's complete." Wow. I replied. before asking if Burt Bachrach had been a big influence for Prefab Sprout. "He wrote very brilliant. adventurous pop songs." describes Paddy. "I realize he made what you would call 'smooth music.' it's not rock music. Whereas I still think what we do is rock—I don't know the distinction in this country. You speak of different things as 'rock' and 'pop.' I sort of blur them together." Paddy. like Keith Richards. is an English pop star; but unlike Richards. Paddy still lives in England. From Langley Park to Memphis was recorded in London and Los Angeles. and was produced, in part, by Thomas Dolby. Dolby manages to infuse McAloon's Bachrach fixation with a modern sheen—Langley Park is filled with broadly melodic, high-gloss pop. The first time I listened to it I gave up halfway through the second song and threw on Between the Buttons. because drums that don't sound like drums kinda freak me out. "The sound on this record," Paddy explains. "is my idea of paying strict attention to the songs and in some cases. forgetting about being a band. It's less of a band album than. say. the last album was. We all play on it. but the emphasis is purely on the songs. I don't play on certain songs; instead I've got the music arranged just the way I want it. Now that makes you unusual compared to a lot of people. like say R.E.M. or the Rolling Stones which are band bands." In the beginning. Though, Prefab Sprout was a band band. Paddy and Martin founded the enterprise around 1980 in their hometown near Newcastle, England. though Paddy had been writing songs (and darn good ones I might add) as early as 1976 or 1977. As a trio, with vocalist Wendy Smith. the group recorded a single for U.K. indie Kitchenware in 1983 called "Lions In My Own Garden (Exit Somewhere)". By the next year. they had been joined by a permanent drummer (Neil Conti) and recorded their debut album. Swoon. "Do you know Swoon. our first album?" Paddy inquires politely. I do: I had been lucky enough to come across it, on one of my post-Richards forays through New York City record stores in search of Prefab Sprout records. in a used bin, tremendously overpriced and marked in great white letters OUT OF PRINT. "I'm glad." smiles Paddy. "Lots of people don't. That is a more unusual record, in the sense that the song shapes and song structures are more unusual." It's actually a quite beautiful record. spread with colorful, impressionistic lyrics sung in Paddy's naive, soulful voice. The jumpy. playful melodies are fenced in by acoustic guitars and light piano arrangements that brought frequent comparisons to Aztec Camera. "The songs I wrote on Swoon were all written on acoustic guitar I've abandoned that slightly." Paddy offers. choosing "Venus Of The Soup Kitchen" from the Langley Park album. as an example. "What I've tried to do here is take some of my favorite elements, things I've come to over the past couple of years. One is a broad. longer sense of melody. So you think. okay. it's a big tune, you want big voices, It'd be good to have a gospel choir!" Paddy chose the Andrae Crouch singers. "Because the intention of the song is that it should be a modern idea of gospel music, which I realize has nothing to do with gospel as it is. but it's a song about being down and out, feeling on the edge of things. But a big melody also suggests Broadway. and yeah. I like Broadway as well. So the overall effect is that people who maybe in the past would think. 'Oh. yeah, Prefab Sprout. a lot of guitars going on there, ' now think. 'Oh. this is slightly different.' Which in some cases is difficult for people to take. and in other cases you reach people. they might be seduced by the overall glamour and romanticism of the song." In the song "Cars and Girls," however. Paddy tries to destructure romanticism by dissecting the romantic imagery commonly used by, say, Bruce Springsteen. The cover an on the British 12″ for the song shows a matchstick figure in torn jeans and a white T-shirt, holding a Fender Telecaster. its sulfur head spurting into flames. "The artwork was a continuation of the cheekiness of the song." explained Paddy. "which was to take a look at Springsteen's main metaphor, which is life's journey. 'Baby we were born to run.' I've pretended to be someone who's heard his songs and doesn't get it: what are you singing about a bike for. a girl on the back of the bike? I don't know any girls. I don't have a bike." Ironically. on the cover shot of Two Wheels Good. Paddy sits on a motorcycle in front of singer Wendy Smith. "It's a deliberate misinterpretation." Paddy continues. "l wanted to say. listen. life is too hard and too big an issue for any metaphor to contain." The night before the interview I still hadn't had any luck securing a copy of Two Wheels Good. so I hit yet another record store, where I found the import matchstick "Cars and Girls" 12″, as well as a 12″ for "Faron Young," the single off Two Wheels Good (titled Steve McQueen in the U.K.). Both were tremendously overpriced. so I picked up a copy of Beggars Banquet to compensate. I don't know what it is with the Stones fixation. I never really got into them as a kid. I just keep thinking there's something missing from pop music today. Anyway. on the B-side of "Cars and Girls." neatly tucked away for people with an irrational fear of modern production was "Nero the Zero," a meaty session leftover laden with heavy electric chords and chiming six-strings. The melody was straightforward and propped up with an ounce of melancholy; in the background hummed a wise harmonica refrain, like a teenager looking down on the follies of society. I played it five times over, it nailed me in the heart, and I told Paddy so. "It's lovely that you should pick up on that," says Paddy with so much sincerity I felt like squirming. "It's one we used to play live when we played in tiny pubs in Durham, where we come from. We went into a local studio in Newcastle for a couple of days and banged down six songs real quick, pretty much live, with a few embellishments. I wrote 'Nero the Zero' when I was 18 or 19, and it has a funny lyric, actually about playing in Durham." Indeed, the chorus ends. But don't you worry / In Durham County / What you're really feeling / You'll soon forget. " "You know what it is," he ponders. "l'm 31, and I went through that, and I like it, but I suppose with the intervening years I've changed in what I want to do. But I still like to go back to that. A lot of songs that I wrote, what I know some people think are some of my best things, I was 19. I was 20. I'm pleased that they still hold up and that people like them, but then I had the feeling of 'I wish I was better.' And I now think I am better. no matter what people think of the new songs compared to the old ones. But I still feel I'm not doing what I want to do. And that's healthy. I still feel I'm in the early days as a writer." Posted in Interviews Previous A Christmas Card from the Band… Next 1977 Demo Recordings Help with Sproutology Running Costs If you find the site useful or interesting, please consider a micro-donation to help with running costs and the purchase of obscure Eastern European magazines containing interviews and so on. Also coffee. Lots of coffee. Sproutmash... The Ultimate Prefab Sprout Song Ranking 2019 Interview Tracker - Sodajerker is BRILLIANT Paddy on George Michael The Essential Non Album Tracks - Where to find them It is happening again... John Birch's book Random Sprout Let's Search the Lofts for Music Jamming – Chris Heath, July 1985 Postbag Roundup – July 3rd Postbag Roundup – March 29th 2015 Prefab Sprout – the Gabriele years The Complete Radio Sessions iD Magazine – March 1988 Weekly Postbag, July 5th 2014 The Story of Steve McQueen © Copyright 2020 - Sproutology
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blink-182-inspired COVID-19 song gets Tom DeLonge, Mark Hoppus nods Joe Smith-Engelhardt Joe Smith-Engelhardt Published: March 23, 2020 People are getting pretty creative during the ongoing coronavirus pandemic in the ways they're offering new takes on music and Tom DeLonge, as well as Mark Hoppus, are showing their support of a new blink-182 cover being remixed to match the situation with the virus. San Diego punk trio Infinite Signal took on the challenge of covering a song about the current pandemic and spun out "Wash My Hands Again" to the tune of blink's "What's My Age Again?". Read More: Post Malone in "quarantine album mode" following tour postponement The band took on the challenge of covering a song about the pandemic and pulled off something truly incredible. "We were challenged to write/cover a song about the current pandemic and it turned out to be a lot of fun. It's important for us to note that we are taking COVID-19 seriously and we are aware of the severity of the virus. However, in uncertain & difficult times like these, it's also important to laugh," they wrote while posting the track. You can see the cover below. We were challenged to write/cover a song about the current pandemic and it turned out to be a lot of fun. It's important for us to note that we are taking COVID-19 seriously and we are aware of the severity of the virus. However, in uncertain & difficult times like these, it's also important to laugh. Wash My Hands Again To the tune of blink-182's "What's My Age Again?" A post shared by Infinite Signal (@infinitesignalca) on Mar 19, 2020 at 7:49am PDT Well, this is funny... :) @infinitesignalca A post shared by Official Tom DeLonge (@tomdelonge) on Mar 22, 2020 at 11:01am PDT What do you think of the blink-182 mockup cover track? Let us know in the comments below. See More: Warped Tour Atlantic City from the pit: ADTR, SWS, Neck Deep and more [envira-gallery id="217198"] Filed Under: blink 182, coronavirus, covers, mark hoppus, Music, tom delonge, what's my age again Categories: Music, News
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As you read this Will, Wigs, and I have begun our first of many drives in the coming months. Today we are making our way out to Los Angeles to get the first couple of interviews and visit some friends. I can hardly believe that this part of our journey has started, it seems like only the other day Will and I were trying to plan it out! So to start this trip with a bang, I'm teaming up with Shabby Apple to give my US readers (sorry international readers) a chance to win a $50 gift card! I am beyond excited for you guys, and I couldn't help but go and pick out a couple of my favorite pieces that I would love to wear during this road trip. Both these shirts look beyond comfy, and when you are sitting in a car for longer than 6 hours every couple of days you want to be comfy for sure. As you can probably guess I absolutely love stripes, they are just so fun! Ok now that you let me lust over some of these pieces a little bit let's get down to the nitty gritty of the giveaway! Optional/Addition Entries: Feel free to do any number of these, just make sure you leave a separate comment for each one. ◦ Tweet about the giveaway "Who wouldn't want to win a $50 gift card from @shabbyapple on @amandagoesmeep's blog?! http://tinyurl.com/b5cwjqa" Wow that's a whole lotta ways to win for sure! The giveaway will run until January 18th. And that's not all folks (haha I kind of sound like an infomercial) the lovely people at Shabby Apple are offering all my readers 10% off your purchase with the use of discount code littleladylittlecity10off good for the next month! Tiny Print: The giveaway is for US readers only and will run until January 18th 11:59 PM EST. The winner will be chosen at random by me via a random number generator. I will contact the winner in a timely mannor (be sure to leave an easy way for me to get a hold of you) and will post the winner on my site shorty after. I love the First Stop skirt. So cute! I'm starting an internship and need to build up my professional wardrobe without looking stuffy, and this skirt would be perfect. and Shabby Apple on Facebook. Oh my gosh, I LOVE the Puca Pucara dress!! Have a safe trip to LA!! I like LLLC on facebook! I follow LLLC on twitter! I follow LLLC on instagram!! Hooray! My fave is definitely the full steam ahead dress in red. Super cute. I love the cider dress! So cute! I love the Barefoot in the Park yellow dress! So simple and comfy looking! I am a follower of yours via gfc and I just liked shabby apple on Facebook! My favorite collection is the light house- I especially love the red and white beach comber dress from them! Being from California I could probably wear it year round! Thanks for the opportunity, I'm so excited! I am obsessed with the One For My Baby dress! Love it! I follow you via GFC, liked shabby apple on fb and I love their alice dress! My favorite piece is Hero shirt in red. Yay Giveaway! I follow you and I like Shabby apple on FB. I would totally get the tigris dress. I follow you via GFC and liked SA on FB ;-) I love the Champs Elysees dress. Following on GFC and liked Shabby Apple on FB. I LOVE the new caledonia dress! L'ete is like the cutest dress ever! I love the sweaters at the top too. Have fun on your road trip, update with cool pictures! I'm a GFC follower and Like Shabby Apple on FB. I love many of their frocks, but my current favorite is the Animalia. and looove the Alice dress! My favorite dress is the Blue Eyes, although I could be really happy with most of them! I love the BE MINE, VALENTINE NECKLACE, it's so adorable. I liked your blog on facebook - Sydney Nicole! oh wow, what a giveaway! I follow you on GFC, liked them on facebook and love the 'dining car' dress - so beautiful! and i followed you on instagram. you can contact me via my blog! My favorite item is the "One For My Baby" dress. It's perfect in every way. I also liked you fb page! I love the Spanish steps dress and the bathing suits! I like the Waimea dress!! GFC: Atreau. I like Shabby Apple on Facebook and I like the ARRIPIDAE dress.
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Taco Shack Hostel (Sairee Beach) was built with the traveler in mind. It is located in Sairee Beach, which is famous for it relaxing beach by day and electrifying nightlife. There are plenty of shops and restaurants close by to please any shopaholic, very easy to walk around from place to place. This property has 6-8 beds mixed aircon dorm rooms with en suite bathroom for your convenience. Each room offers large comfortable mattress, your own power outlets and nightlight. There is fast free Wi-Fi throughout the building, hot showers, and metal lockers for your safety. The rooms have a balcony to relax on with fantastic sea view. Breathtaking sunset view, 2 garden terraces and a huge rooftop for chilling out while watching the sunset - also used for movie nights. The restaurant serves great Mexican food with an island twist for those travellers who are a bit bored of rice and noodles. Every evening we set up games and activities for guests to make new friends and socialize with cheap beers, cocktails, and of course, buckets. - We reserve the right to cancel any reservation after 19:00, please email us if you are running late. 2. Check-out Time: until 11 am. (1) Half day fine for late checks out during 12: - 16:00. (2) 1 day fine for late check out after 16:00. 3. Payment: Cash, credit card or Paypal is welcomed upon arrival. 5. Age Restriction: The minimum age to check in is above 17 years old, no children.
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I have genuinely missed blogging! So then why haven't I blogged? I'm sure you can already guess my answer, but I've just been busy. The worries of every day life has gotten the best of me. On top of that, I was feeling a bit uninspired, to be honest. 1. Tired, so I just did not have the energy to work something up. 2. Life got a bit busy so I had to reprioritize a bit in order to stay somewhat sane. I've redone my blog a bit, YAY! I personally love the cleaner, more simple look. I'd love to hear what you think! I wanted to start up blogging again. I've been able to start 2016 with a more disciplined schedule that allows me to have some more time to do something other than go to work, school, and do homework. Therefore, I thought I'd put in some time creating some content for you to read/view. To begin, I thought I'd share some of my favorite moments from 2016 so far. ♥ My love and I began the year with some sparkle and floral. I'd say dressing up was my favorite part of New Year's night. You may think otherwise, but I absolutely loved our outfits. ♥ There's a new sightseeing place that opened up in Philadelphia towards the end of 2015, the One Liberty Observation Deck. You're basically 57 floors above Philadelphia and it is absolutely stunning, especially to watch the sunset! It made me realize how much I take the beauty of my city for granted as I walk the streets daily. ♥ If you're ever in Philadelphia, I highly recommend stopping by for a nice dinner at Bank & Bourbon. We went there the evening before Valentine's Day and everything about the place was abdolutely divine! The food, the service, the atmosphere. You can also stop by the Loew's Hotel next door and take the elevator to the highest floor to see another beautiful view of the city. Hope you enjoyed reading this little tid-bit! I'm so excited to start blogging again and am so excited to have a new post up again for you on Monday! How has your 2016 been lately?! I'd love to hear about it!
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End of Season cricket pitch works – defining processes…. Over the years I've worked on literally hundreds of natural turf cricket pitches, ranging from village grounds to first class and International venues. When surveying these pitches, assessing their fitness for purpose and making recommendations for works to remedy key cricket pitch issues I've always mulled over how to best to explain, in simple terms, the options for cricket pitch works to the club man and groundsman. A couple of years ago I sat down and did exactly that; creating a document that defines works into four key categories – or processes – and which has subsequently been agreed a good structure by ECB Pitch Consultant Chris Woods. Over the next few months I'll look in more detail at each of these processes – End of Season Renovation, Table Construction (Full Pitch and Profile), Square Restoration and Profile Regeneration – highlighting the kind of issues that each can help to remedy and any limitations. The processes range in scope from regular end of season works through to the construction of a brand new cricket table to remedy even the most severe of problem cricket pitches. The intermediary processes offer revolutionary solutions that can help address issues such as uneven surface levels, saddling, thatch and profile layering with immediate improvement to performance. While any process would need the fine detail tweaking to suit the individual attributes of the cricket pitch in question, this series should provide club groundsmen with a good insight into what works they should plan for.
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Q: How can I validate the date is not the future date in .net c# Just wandering, how can I validate the date is not the future date in .net c#. Example: I have applied a validation there for required field validation. But somehow I have no idea how to apply the validation to check the start date to make sure it's not the future date (date not greater then the current date)? <tr> <td align="right">Start Date:</td> <td><asp:TextBox runat="server" ID="activeDate" size="8"/>(YYYY-MM-DD) <asp:RequiredFieldValidator ID="reqvactiveDate" runat="server" ControlToValidate="activeDate" Display="Dynamic" EnableClientScript="true" ErrorMessage="required" /> </td> </tr> than I wrote the following code to tried out the date validation. The date validation doesn't seem working for me :( <tr> <td align="right">Start Date:</td> <td><asp:TextBox runat="server" ID="activeDate" size="8"/>(YYYY-MM-DD) <asp:RequiredFieldValidator ID="reqvactiveDate" runat="server" ControlToValidate="activeDate" Display="Dynamic" EnableClientScript="true" ErrorMessage="required" /> <asp:CustomValidator runat="server" ID="valDateRange" ControlToValidate="activeDate" onservervalidate="valDateRange_ServerValidate" ErrorMessage="enter valid date" /> </td> </tr> code behind: protected void valDateRange_ServerValidate(object source, ServerValidateEventArgs args) { DateTime minDate = DateTime.Parse("1000/12/28"); DateTime maxDate = DateTime.Parse("2011/05/26"); DateTime dt; args.IsValid = (DateTime.TryParse(args.Value, out dt) && dt <= maxDate && dt >= minDate); } A: I think you're getting the error for this: DateTime.Parse("1000/12/28") Instead, try DateTime.MinValue. You can also optionally use compareValidators.. Also, any reason you are not just doing [your date] < DateTime.now ? A: DateTime implements an IComparer interface. Check if its greater than DateTime.Now There is no reason to parse it, just do: if(datetime1>datetime2) { .... } A: Here is my code that does the validation of the date value not to be in the future on the client side: ASPX code: <tr> <td align="right"> Start Date: </td> <td> <asp:TextBox runat="server" ID="txtActiveDate" size="8"/>(YYYY-MM-DD) <!-- Validate if the entered date value is valid --> <asp:CompareValidator ID="cvIsActiveDateValid" runat="server" ControlToValidate="txtActiveDate" ErrorMessage="Invalid Start Date" Operator="DataTypeCheck" Type="Date"></asp:CompareValidator> <!-- Validate if the entered value is not future dated --> <asp:CompareValidator ID="cvIsActiveDateNotInFuture" runat="server" ControlToValidate="txtActiveDate" ErrorMessage="Start Date cannot be a future date." Operator="LessThanEqual" Type="Date"></asp:CompareValidator> </td> </tr> ASPX.CS code: protected void Page_Load(object sender, EventArgs e) { SetTodaysDateToCompareValidators(); ... } protected void SetTodaysDateToCompareValidators() { string defaultDateFormat = "YYYY-MM-DD"; string today = DateTime.Today.ToString(defaultDateFormat); cvActiveDate.ValueToCompare = today; }
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V1-1's are engineered to be leak-free, maximize flow and reduce the overall cost of ownership. So confident of their performance, only ValvTechnologies' V1-1 valves are backed by the best four year, zero-leakage warranty in the industry*. Backpressure protected sealing. Standard with the V1-1 valves, the design prevents the upstream spring from collapsing in a reverse flow condition, protecting the internals from damage and guaranteeing shutoff in the reverse direction. Requirement: Immediate shipment of a V1-1 metal seated ball valve for main steam draining was required to avoid extended outage time. Result: Receiving the emergency request on Saturday, ValvTechnologies quickly assembled a cross-functional team to provide the power plant with an immediate solution. Representatives from the Shipping, Warehouse and Service departments were called to the Houston office to solve the customer's issue. The ValvTechnologies' team was able to identify, assemble, test and ship a replacement V1-1 valve by the end of day Saturday, the very same day the emergency request was received. The customer received the V1-1 valve Monday morning and immediately installed it. The new valve functioned perfectly and the customer was able to go back online, saving thousands of dollars in potential down time and revenue loss. Background: Power plants around the world commonly use ball valves to control high-pressure spray water in their cooling towers. In these towers, water is sprayed through pressurized nozzles for cooling and reuse. A power plant in Poland was utilizing globe valves instead of ball valves for their spray water control. Their particular application required the valves to open and close at rapid speed. For this application, the globe valves were failing continuously, resulting in control loss of the spray water and decrease in plant efficiency. Additionally, the globe valves' stem packing was tearing, causing high-pressure, high-temperature water to be sprayed around the malfunctioning valves, creating a dangerous environment for operating staff. Requirement: The customer requested ValvTechnologies review their spray water application and recommend an alternative solution that would replace their bare stem valves but keep the existing actuators and positioners. They also required each gearbox be replaced and changed to rotating movement from linear movement. Additionally, all valves provided were required to be in accordance with FED and CE requirements. Most importantly, the plant required each valve to function without issue and without the replacement of any stem packing for a period of one year from the date of install. Solution: The ValvTechnologies' high-performance V Series ball valve was identified as the best solution for this application. Per the customer's specification, eight V1-1 valves were installed to replace the existing globe valves. After one year of operation, ValvTechnologies inspected the eight valves using an endoscope and found no sign of erosion or stem-packing problems. See photo 1 and 2 below. Plant management has approved the replacement of all globe valves used for spray water control to ValvTechnologies' V Series ball valves. ValvTechnologies' provided this customer with the best total cost of ownership solution available. ValvTechnologies was able to eliminate an unsafe environment, increase the quality of the spray system and improve plant efficiency. Background: A low-carbon economy is a concept that refers to an economy which has a minimal output of greenhouse gas emissions into the biosphere, specifically greenhouse gas, carbon dioxide (CO2). A power station near the town of Selby, England, is the largest, cleanest and most efficient coal burning power station in the United Kingdom. With a generating capacity of 3,960 megawatts, its current output levels generates enough electricity to meet the needs of seven percent of the United Kingdom. Understanding they have a very important role to play in the transition towards a low-carbon economy, this power station is committed to reducing hazardous emissions and has various projects ongoing which will not only reduce emissions, but deliver significant savings. Solution: Severe service valve leakage significantly reduces a plant's heat rate performance, because BTUs leak away, never reaching the turbine. By utilizing ValvTechologies' V Series metal seated ball valves and IsoTech® parallel slide gate valves for vents and drains, steam and water leakage is eliminated, improving the plant's thermal efficiency. Additionally, less fuel is burned to produce megawatts, which not only leads to lower emissions, but improved plant efficiency.ValvTechnologies' high-performance zero-leakage isolation valves typically improve a plant's heat rate performance by 1-2%, even up to 5-6% in some cases. In 2004 ValvTechnologies began suppling this power station with V Series severe service ball valves for problem areas such as drains and bypasses. Result: Due to the V Series valves reliability of isolation provided on the plant's drains and bypasses, the plant began using ValvTechnologies' IsoTech® valves their feed waters systems (start and standby feed pumps, HP heater feed inlet and outlets). The feed system pumps powerfully move water at a rate of 150 gallons every second. The IsoTech® valves provided single isolation, allowing maintenance to be carried out on tube leaks without shutting down the entire system. ValvTechnologies' zero-leakage valve range is seen as a solution provider where isolation is required for critical and severe service applications, and the way forward in helping achieve the targets set for reducing emissions. It is critical to chose the correct valve specifications when it comes to attemperator block valves. When zero leakage is demanded for improved plant heat rate efficiency and for overall increased megawatt output, ValvTechnologies offers its' V series, zero leakage, metal seated ball valve for attemperator spray block valve applications. Specialty industries: Other industry solutions available. Contact the factory for more information.
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Show most relevant results first | Most recent results are first | Show use by person Search only Marc MacSharry Search all speeches Results 21-40 of 5,442 for "section:" . (isset($hansardmajors[$1]["title"]) ? $hansardmajors[$z[1]]["title"] : "$z[1]") speaker:Marc MacSharry Written Answers — Department of Public Expenditure and Reform: Pension Provisions (26 Nov 2019) Marc MacSharry: 177. To ask the Minister for Public Expenditure and Reform further to Parliamentary Question No. 153 of 1 October 2019, when a determination will be made on the appeal (details supplied); and if he will make a statement on the matter. [48654/19] Written Answers — Department of Employment Affairs and Social Protection: Invalidity Pension Applications (26 Nov 2019) Marc MacSharry: 500. To ask the Minister for Employment Affairs and Social Protection when a person (details supplied) in County Sligo will receive a decision on an invalidity pension application; and if she will make a statement on the matter. [49083/19] Written Answers — Department of Employment Affairs and Social Protection: Invalidity Pension Appeals (26 Nov 2019) Written Answers — Department of Transport, Tourism and Sport: Sports Capital Programme (21 Nov 2019) Marc MacSharry: 18. To ask the Minister for Transport, Tourism and Sport his views on whether the sports capital funds allocated for 2019 are sufficient; and if he will make a statement on the matter. [48145/19] Written Answers — Department of Transport, Tourism and Sport: Haulage Industry (21 Nov 2019) Marc MacSharry: 31. To ask the Minister for Transport, Tourism and Sport the specific measures planned to assist hauliers in view of the higher operating costs and considerable negative impacts that Brexit will create for the industry. [48143/19] Written Answers — Department of Transport, Tourism and Sport: Public Transport (21 Nov 2019) Marc MacSharry: 39. To ask the Minister for Transport, Tourism and Sport if his attention has been drawn to the considerable capacity issues across the public transport system; and if he will take steps in the short to medium-term to address same. [48147/19] Written Answers — Department of Transport, Tourism and Sport: Public Transport Initiatives (21 Nov 2019) Marc MacSharry: 42. To ask the Minister for Transport, Tourism and Sport if he has considered establishing a transport security unit to tackle widespread and dangerous antisocial behaviour on public transport and at public transport hubs. [48144/19] Written Answers — Department of Health: National Treatment Purchase Fund Data (21 Nov 2019) Marc MacSharry: 157. To ask the Minister for Health the breakdown on the year-to-date distribution of the 2019 €75 million budget of the NTPF amongst each private and public hospital benefitting from same; and if he will make a statement on the matter. [48457/19] Marc MacSharry: 158. To ask the Minister for Health the amounts paid to individual public hospitals receiving NTPF and other HSE funding for the purposes of insourcing and outsourcing of surgical procedures; and if he will make a statement on the matter. [48458/19] Marc MacSharry: 159. To ask the Minister for Health the number and types of surgical procedures and treatments carried out to date in 2019 by each public and private hospital under the NTPF scheme; and if he will make a statement on the matter. [48459/19] Written Answers — Department of Transport, Tourism and Sport: Penalty Points System Offences (21 Nov 2019) Marc MacSharry: 208. To ask the Minister for Transport, Tourism and Sport if he is considering measures to ensure that in circumstances in which a person is found guilty of a penalty point offence, the correct number of penalty points are endorsed on their licence. [40157/19] Written Answers — Department of Transport, Tourism and Sport: Taxi Data (21 Nov 2019) Marc MacSharry: 216. To ask the Minister for Transport, Tourism and Sport the number of taxi drivers operating illegally; the measures he is taking to follow up on such taxi drivers; and if he will make a statement on the matter. [48452/19] Written Answers — Department of Health: Vaccination Programme (19 Nov 2019) Marc MacSharry: 467. To ask the Minister for Health if his attention has been drawn to the fact that there have been no BCG vaccinations for babies since May 2015 due to a shortage of the vaccine here; and if he will make a statement on the matter. [47770/19] Written Answers — Department of Education and Skills: School Transport Administration (12 Nov 2019) Marc MacSharry: 183. To ask the Minister for Education and Skills if he has requested individual accounts from Bus Éireann in view of the fact that a company (details supplied) would have to audit the separate annual profit and loss accounts for the provision of school transport in order to audit the statutory account of Bus Éireann as published in the annual reports; if he is in receipt of the... Written Answers — Department of Transport, Tourism and Sport: Air Services Provision (12 Nov 2019) Marc MacSharry: 468. To ask the Minister for Transport, Tourism and Sport the process by which fifth freedom aviation agreements are set out. [46123/19] Marc MacSharry: 469. To ask the Minister for Transport, Tourism and Sport the process through which the safety standards of partner airlines that are applying for or have been granted fifth freedom flight rights are verified and assessed. [46124/19] Marc MacSharry: 470. To ask the Minister for Transport, Tourism and Sport the number of permits issued to airlines outside the State under the fifth freedom over the past five years. [46125/19] Marc MacSharry: 471. To ask the Minister for Transport, Tourism and Sport his views on the granting of fifth freedom traffic rights to an airline (details supplied) for the Dublin to Madrid route; his views on whether the decision potentially creates a competitive distortion in view of the different obligations on an airline with such rights; the policy in this regard; and if he will make a statement on the... Written Answers — Department of Employment Affairs and Social Protection: Jobseeker's Benefit Eligibility (12 Nov 2019) Marc MacSharry: 523. To ask the Minister for Employment Affairs and Social Protection when the provisions for the self-employed to have access to jobseeker's benefit will be enacted in view of the Social Welfare Act 2019 being signed on 24 October 2019; and if she will make a statement on the matter. [46013/19] Written Answers — Department of Transport, Tourism and Sport: Rail Services Provision (6 Nov 2019) Marc MacSharry: 188. To ask the Minister for Transport, Tourism and Sport the status of the purchasing of additional rail carriages for Iarnród Éireann; and the date by which he expects these carriages to be delivered. [45730/19] Result page:« Previous 1 2 3 4 5 6 7 8 9 10Next » Being alerted to new search results Subscribe to an email alert for "section:" . (isset($hansardmajors[$1]["title"]) ? $hansardmajors[$z[1]]["title"] : "$z[1]") speaker:Marc MacSharry Or get an RSS feed KildareStreet search is case-insensitive, and tries to match all the search terms within a document. 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Word to the wise – when a flight attendant asks you to turn off your cell phone, turn it off. I have always been amazed at the audacity of individuals who choose to ignore multiple instructions from a flight attendant to turn their cell phones off. In every previous case that I have witnessed, the instructions are normally heeded before the flight attendant has to take it to the next level and begin issuing warnings. Not on my flight last night. A woman a few rows ahead of me and across the aisle was warned multiple times to turn her cell phone off. When she ignored the flight attendant, she was then told that further refusal to comply with the flight attendant's instructions would result in the plane having to return to the gate where she would be escorted off the plane into the welcoming arms of airport security. Apparently the thought of having to pay hefty fines and face possible federal criminal charges wasn't enough to persuade her into ending the conversation. After entering into a heated discussion with the person behind her (who just wanted her to end the call so everyone could get on their way), the flight attendants had enough and ordered the plane back to the gate where the unruly woman and her unlucky travelling companion were politely escorted off the plane to the cheering applause of the rest of the paying customers who could now continue on with their travels. While we've all complained about how much our cell phone bills keep increasing, something tells me this woman may have just placed on of the most expensive phone calls ever made on a mobile device. Although I was surprised that someone would choose to act this way and potentially have a negative impact on the travel plans of almost 200 other people, I was equally amazed at the response of those other 200 people. Not once did I hear anyone complain or grumble about the situation. They simply accepted it as it was and let the flight attendants do their job. Flying is stressful enough as it is. When you add this explosive situation to the simmering cauldron that exists in most of us trying to fly from point A to point B, you expect some sort of expression of exasperation from the affected actors. Not on this flight. Maybe it was the realization that the flight attendants weren't going to put up with much or the thought of the potential walk of shame through a throng of cheering spectators was enough to deter them. Whatever it was, it worked and I was proud of my fellow travelers. I don't get to say that often so I couldn't pass up the chance to say thank you to the crew and passengers on Southwest flight 4634 from FLL to MDW on September 3rd for handling a delicate and tricky situation in the best way possible. Kudos! Have you encountered any similar situations during your travels or flights in particular? How did the crew and passengers handle it? How did you handle it? Share your stories and advice and you could possibly make someone's next flight a little bit easier. Well said. I was concerned the flight crew would back off their warning and I applaud them for not doing that. Hopefully the lesson was learned. Is this Facebook? Can I "like" this entry? Top notch story, and a great end to what appears (via other FB posts) to have been a great vacation! Thanks for the kind comments, Bruce! Did I also mention that the plane fishtailed upon landing? It was a great vacation and a memorable ending!
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The holidays are upon us, and that means it's time to start planning (and saving) for all the gifts and stocking stuffers you'll be purchasing over the next few weeks. I'm willing to bet there's at least one Harry Potter super-fan on your shopping list, and chances are, they already have enough Harry Potter mugs, Harry Potter candles, Harry Potter collectable books, and Harry Potter home accessories to fill a storage unit. So if you're looking to gift them something they don't already have, try your hand at this DIY Golden Snitch Necklace. The entire step-by-step process is featured below, and it's so easy, you can have it totally complete before you've finished marathoning the first Harry Potter movie! Find out how to DIY a Golden Snitch Necklace below, and get the details on 29 other Harry Potter crafts in The Unofficial Guide to Crafting the World of Harry Potter by Jamie Harrington, available wherever books are sold. The Golden Snitch is the most important part of any Quidditch match, which makes the Golden Snitch Necklace one of my favorite pieces of jewelry to create. It's important to follow the directions exactly, or you might end up with one of your wings upside down or flipped around backwards! 1. Use your wire cutters to cut your small gold chain into 2 even pieces of 9." each. 2. Next use your jewelry pliers to open a jump ring. Do this by grasping the jump ring with the pliers, making sure the split in the ring faces up, and holding the other side of the ring with your fingers. Now slowly and gently twist the pliers toward you and twist your other hand away from you. 3. Thread the open jump ring through the last link of one of the jewelry chains. 4. Now thread the small loop on the end of the jewelry clasp through this same jump ring. Use your jewelry pliers to squeeze the jump ring closed by holding one side of the ring with the pliers and the other with your fingers. Twist the sides toward each other to bring them together and close the ring. 5. Use your jewelry pliers to open your second jump ring. Thread the last link of the other jewelry chain (the one without the clasp) through the jump ring and then use your pliers to close the ring. Your clasp will attach to this ring to connect the finished necklace ends. 6. Run the gold eyepin through the gold bead. 7. Cut off the excess wire using your wire cutters. 8. Use your pliers to bend the recently cut end of the eyepin into a small loop. 9. Arrange your necklace pieces as shown in the photo. This is how the necklace will fit together. 10. Open a third jump ring and thread it through the tip of one of your gold wing charms. Then thread the last link of one of the chains through the jump ring. Close the jump ring. Repeat this using your fourth jump ring, the other gold wing charm, and the other half of the necklace. 11. Open the jump ring that came attached to the gold wing charm. Thread the ring through one of the loops on the gold bead. Close the ring. Repeat this using the other gold wing charm and the other loop on the gold bead. 12. Now you have the cutest little snitch necklace ever! Wear it and enjoy. You can decide how long you want your necklace to be. Just cut your chain to whatever size you want! Excerpted from The Unofficial Guide to Crafting the World of Harry Potter by Jamie Harrington. Copyright © 2016 F+W Media, Inc. Used by permission of the publisher. All rights reserved. Photos courtesy of iStockphoto.com and F+W Media, Inc.
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and Omelia BADDER to Simon MIFFIN 1866 p73. Was widr when married 1825 Catherine BURCH Who was wf1 Any ch? wit : John BALMER and Emily PRINCE. Lewis died 1869 Rachel died 1876 Where are they bur? What twp was Lewis born Who were prnts? Where from? ml899 Elizabeth Jane DARROCH Portage LaPrairie MB, Edith, Fern, Alice. witns Clara M BARRETT of Uxbridge relationship? Any desc of Mary or Clara? Are they all related? How? Does this group belong to McCOMBS from Niagara area? George BAYNHAM born 1853 London twp Middlesex Co died post 1929? Poss 1 son lost in WW1 who? John Baptist bc1786 PQ wife Dorathea poss APPLETON? bc1792 ON? Rosanna/ L CHAPELLE m2 REED?/ REID, Edward/ M PROULX? Other CH? Where did she go? Bur? Elizabeth D. c1870, Mary Ann G. c1873, John C. Wesley c1878. Agnes DENTON 23 to James WINGROVE 30 Jan 1867 p95. of Charles DESROCHERS or DUROCHER or DEROCHER, wife Julie HOULE, son Noe. Have Noe married Notre Dame RC Hull Que 1891 to Georgianna BEAUDIN. Seek 1871,81,91 census trail of David ARCHY, wife Mary DARNEL, dtr Sara. Have Sara married Sainte Anne RC Sudbury Ont 1893 to David BEAUDRY. Charles BEZZO bc1831 Norfolk Co m Mary Ann SMITH dtr of Isaac SMITH? when? Was Charles s of Andrew BEZO and Sophia BEAUPRE? Johanna BEISE, 26, St. Catharines, St. Catharines, died of James and Sarah." Series 1-6 B, Volumes 1 - 86 for additional information. 1932 Canal Road, P.O. box 3012, Saint Catharines, ON L2R 7C2. neither record gives the maiden name of their mother Mary. Charles Alexis in Grey Co ON 1830s disappears poss to USA Louisiana? Seek info desc of Henry LOUCKS and Esther HACKNEY Orford Kent married 1876. Cordelia LOUCKS married 1909 William Ira BICUM of Harwich. Alice LOUCKS married 1910 Henry DICKMAN. Rebur within Toronto 1854-1855 but can't find where. Have 1900 Sudbury marriage and 1943 Sudbury obit for William Foster JARVIS born Madoc Tp Hastings Co Ont ca 1875 : siblings Walker of Flin Flon, James of Calgary, Mrs R. BIRD of Marmora. Seek additional info on siblings, father James JARVIS, mother Sarah JOHNSON. Seek marriage ca 1850 Oliver BISSON to Marie Delphine LATOUR- FORGET. wit : William PAXTON and Joseph GOATBY. wit : Joseph and Thomas GOTBY. mar 28 Jun 1840 wit : Joseph and Ann HOWARD. Jean b?d? m Mathida FOURNIER b?d? prnts of Jean Baptist b?d? son of Jean Baptiste/John BOURDEAU and Minnie/Marie LETOURNEAU, m when? where? Church of Eng with Tos DEWER and Charlotte BOWLS, both of Beckwith, as witnesses. Joseph s of Joseph BRANKLEY engineer Great Lakes ship killd c1870 where? Seek desc/reltvs of Lawrence CONWAY bc1810 where? mc1840 Th�r�se RENAUD bc1820 where? sis poss Jessie McCLOUDE Vilma had 2 sis who? Seek 1891 and 1901 census listings for William BUATOALA, wife Katharine, dtr Eva Maria born 1891. Have Eva Maria CofE baptism at Copper Cliff near Sudbury 1891 but family was not in Sudbury 1891 census. Mary M. CARTER 17 of Malahide, born Malahide, dtr of Silas and Levas? mar 1 Oct 1861 Ellen MIDDLETON 21 of Malahide. son of Peter FISHER and wife Mary Jane KILLABY. son of Robert ORMSBY and Eiiza McMAHON m LiIIian? Where? Any fam? Bur Beachwood cem Ottawa Did he live in Australia? lvd con 7 Lot 10 1851 cens very large fam Where did they come from? George and Lydia? born where? Their son my grgrgrpa William Charles born where sibs? William born 1847 Montreal PQ son of Charles TOMLINSON and wife Mary Ann ? Samuel Finnlayson m Florence GAUDAIR and Esther Francis.
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of the museum itself? When does online digital content become a genuine museum experience? This paper looks at how both science and art museums use digital channels to engage substantial non-visiting audiences with digital media. Using Wellcome Collection, the free museum and library for the incurably curious as a case study, we will look at how digital transformation and a product-centred approach to the website allowed us to build a content team that works alongside other product teams to challenge people's ideas about health and make connections between art and science. We ask what the experience of journalism brings to museum content and the role of social media in amplifying narrative content, creating dialogue with visitors and increasing our understanding of audiences. We'll talk about the challenges we've faced in this approach and include the experiences of other digital content people, who have experimented with this approach in museums . Digital content can address a diversity strategy through bringing new voices in to speak through the museum. We will share insights about our analytics, audiences and how we measure the impact of our work and its value to the organisation. Finally, we ask what difference it could make to museums to commit to a strategy of using online digital content to reach audiences well beyond their visitor base, to participate in public debate, and to add to the overall public engagement with art, science and cultural heritage.
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These days, novelty accounts are all the rage. In most cases, novelty accounts centered on celebrities are parodies that point out their flaws. But when it comes to world-renowned DJ The Black Madonna, her Twitter bot might actually be a form of flattery. It's no secret that The Black Madonna is one of the most outspoken voices in dance music. In keeping with Chicago house music's socially progressive roots, she is often first to criticize politicians and expose misogyny in the music industry while championing LGBT rights. On the other hand, The Bot Madonna (@botmadonnachi) is a (presumably) bot Twitter account that randomly tweets snippets that The Black Madonna (@blackmadonnachi) used. The bot account first began tweeting on June 6, and as of August 16, is almost at 2,500 tweets. Whoever put this bot account together seems to have a keen awareness of the DJ's prestige. The bio, which reads "2016 MixMag! Bot of the Year", is a reference to Black Madonna's title as Mixmag DJ of the Year in 2016. Here are some highlights from The Bot Madonna. Going through middle America isn't great? Going through the bot account's feed is an experience that sums up Black Madonna's Twitter presence quite succinctly. Intrigued? Follow The Bot Madonna (@botmadonnachi). But you probably need context first, so you might want to follow The Black Madonna (@blackmadonnachi) first. Feature image courtesy of Aldo Paredes and Billboard.
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Korea Launches First Official Music Charts Gaon By Han Sang-hee Popular K-pop songs will now be listed on a local music chart resembling the United States' Billboard Charts, enabling both fans and artists to further enjoy, protect and spread K-pop music. The Ministry of Culture, Sports and Tourism and the Korea Music Content Industry Association launched the ``Gaon'' Charts at a hotel in Seoul, Tuesday, with hopes that it will create a more systemized and reliable music industry. The word ``gaon'' means ``middle'' or ``center'' in Korean, and it was chosen to represent fairness and reliability. Compared to U.S.'s Billboard Charts, which was launched in 1940, and Japan's 42-year Oricon, the local chart may be a bit late on the international music scene, but experts are expecting it will work as a well-balanced and an upgraded version of music charts. The Gaon Chart is based on both online and offline data of album and music sales. It has ruled out radio airings, which play an important part in the Billboard Charts, and decided to focus on the transaction between music and buyers. ``It was only last year when we started this project. We have done many things to protect the rights of our musicians and their works, and I believe this chart will help as well. Music charts work as a bridge that introduces, spreads and exchanges musical contents to the world, and I believe this will be a chance to nurture the music industry,'' said Culture Minister Yu In-chon. The local chart is divided into five categories: the Gaon Chart, Digital Chart, Online Chart, Mobile Chart and Album Chart. The Album Chart sums up album sales by six major album distributing firms such as LOEN Entertainment, SM Entertainment, Sony Music Korea, Warner Music Korea, Universal Music and Mnet Media ―while the Mobile Chart will estimate the best selling ringtones and caller ring tunes each week. The Online Chart will calculate music source sales, online album sales and streaming services. Finally, the Digital Chart will sum up Online and Mobile Charts, while the Gaon Chart will present the final list that accumulates all of the top results. The Gaon Chart will be released once every six months, while the other four will be released offline and online on a weekly basis. Online results will be made by calculating data given by top music Web sites such as Melon (www.melon.co.kr), Dosirak (www.dosirak.co.kr), Mnet (www.mnet.com) and Cyworld (www.cyworld.com). According to the association, the offline and online data will be those based on the results made by approximately 97 percent of Internet users who purchase music online. Meanwhile, popular girl band Girls' Generation and boy group Super Junior took first place in the digital and album sales categories last year, respectively. According to the association, Girls' Generation's ``Gee'' was the most popular song, while Super Junior's ``Sorry Sorry'' sold the most albums throughout Korea in 2009. Steve Choi, the director of the Korea Music Content Industry Association, explained that the online estimates needed more polishing, as they have not yet come up with a definite strategy on how to calculate online data. ``The Gaon Charts you see today is not the final product. It's the beginning of Korea's official chart and we need to polish it up for the time being,'' he said. Indeed, the Gaon Charts is in its infancy. It is yet to be released in other languages other than Korean and still has a long way to go to be acknowledged by fellow countries. While major charts such as the Billboard Charts and the Oricon Charts categorize their system depending on the music genre, radio airings and type of albums, respectively, it has categorized its charts based on online and offline sales. This had made it a leading charting system in the digital age of music purchasing, but whether it will successfully be embedded in the music industry remains in question. ``We have never had an official music chart, despite the popularity of K-pop around the world. The music industry has changed drastically thanks to the Internet, and the Gaon Charts will be in the forefront of such changes in both technology and music distribution,'' said Bang Geuk-gyun, the head of the Korea Music Content Industry Association. Internet users can find the Gaon Charts by visiting its Web site at www.gaonchart.co.kr. sanghee@koreatimes.co.kr
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I just picked up Canon's new 40mm f/2.8 STM pancake lens. I'm going to post some test footage later, but couldn't wait to share. When I started shooting I had an entry level DSLR that at the time (2007) shot video, but it wasn't great and the sound quality was horrible. Now 5 years later, even entry level DSLR cameras shoot HD video and can record incredible sound with an external mic. Because my DSLR couldn't be used for video I had to also bring an HD video camera. I looked kind of silly, I shot stills with my DSLR and built a bracket that would hold my HD video camera on it. I was a one man show so I had to improvise.
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In this talk, I will describe how to improve the performances of light emitting diodes (GaN-based and GaInP based) and III-V solar cells by MEMS technology. Using the MEMS technology containing wafer bonding, electroplating and smart cutting, epilayers can be separated from epitaxial substrate and transferred onto the functional permanent substrate. Using the same process, the traditional ribbon microphone is all also miniaturized and fabricated into mini-ribbon microphone. Ray-Hua Horng received her Bachelor of Science degree in 1987 from the Department of Electrical Engineering, National Cheng Kung University, Tainan, Taiwan and her Ph.D. degree in 1993 from the Department of Electrical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan. She is currently a professor in the Department of Electro-Optical Engineering at the National Cheng Kung University, Tainan, Taiwan. She has worked in the Research Laboratories of the Industrial Technology Research Institute (ITRI) in Hsin Chu, Taiwan and taught in the Department of Electrical Engineering at Da-Yeh University in Chang Hwa, Taiwan and the Graduate Institute of Precision Engineering at the National Chung Hsing University in Taichung, Taiwan prior to her current appointment. Her research interests include solid-state lighting devices, solar cells, flexible electronics, optoelectronics, nitride and oxide semiconductor MOCVD growths, and mini-microphones. This entry was written by Scott Melvin, posted on April 26, 2011 at 2:28 pm, filed under Communications Society Chapter, Computer Society Chapter, Events. Bookmark the permalink. Follow any comments here with the RSS feed for this post. Both comments and trackbacks are currently closed.
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IFComp Scores Filed under: IFComp,Interactive Fiction — matt w @ 9:37 am Tags: interactive fiction, Interactive Fiction @SoM The deadline for IFComp voting is tomorrow. I haven't finished posting my reviews, but I've played all the ones I'm going to vote on, and I've submitted my scores. So here's the scores, with a brief non-spoilery explanation. My base line is that a solid, substantial game that I generally enjoyed playing and that sent me to the hints a few times gets a 7. As Sam and I said, there doesn't seem to be any clear front-runner this year; I thought a lot of the games were either very short or hugely ambitious but flawed. Anyway, scores and mostly spoiler-free explanations below the jump; full reviews here for elaboration on what I'm talking about. A word on the two-hour time limit. Unlike the other year that I thoroughly played the comp, this year a lot a lot of the games were long enough that I couldn't finish them within two hours, or even close. I don't time my playing (partly because I tend to play for a few minutes, leave the game open, do something else, come back for a few minutes), but I made a good-faith effort to discount everything that happened in my playthrough after around two hours of play. Some of those are noted below. If a game gets me to play for two hours, that's generally something of an accomplishment. Games are listed in order of their score; games with the same score are not listed in any particular order. PataNoir: 9. A great gameplay idea, lots of puzzles, the writing isn't absolutely top-notch and some of the puzzles are a bit confusing which keeps it from a 10. The most confusing puzzles came after the two-hour limit. The Play: 8. An excellent choice-based game with a good mechanism and with some things to say. Again, the writing is good but not enough to put in the top bracket; if Christine Love had written it it'd probably be a 10. (Well, that's true of anything.) As Carl observed, the slapstick doesn't really work in the medium; slapstick can work in IF (more in my Death of Schlig review) but this particular slapstick doesn't have the "a bunch of little disasters piling up on the player" mechanism that makes that go. The author has other things to do. The Hours: 8. I'm not sure I can justify this vote, but this may have been the playthrough I enjoyed most. The forward momentum of the play was enough to take me past its polish issues, and as I said that was part of the charm for me. Still probably should be a 7, but I'm rounding up because no one else seemed to like it. (Also, Carl says that your seemingly inconsequential dialogue choices affect the ending, which is kind of innovative and done subtly enough that I didn't notice it.) Cana according to Micah: 8. Makes it for the great atmosphere and the NPCs. And the hint system; most of the puzzles seemed pretty much unsolvable to me (I'm going to have to think about whether there's a single one I solved on my own), although that may be partly because of my unfamiliarity with the details of the Bible story. But I enjoyed playing through with the hints. Taco Fiction: 8. Funny and engaging. Basically starts off with a 9, gets two points docked for a timed puzzle that wound up being out of sync with the spirit of the playthrough, gets a point back for implementing a hilarious action (though that was part of the reason that I didn't expect the timed puzzle to bite me). Would probably lose something more for the best ending either being completely bugged or inadequately clued and hinted, but I found that out after more than two hours. [UPDATE: I am informed that the ending is working as intended, but that setting it up requires doing some stuff that I had done in my first playthrough but not my second, which provides the PC with the necessary motivation. Apologies, Mr. Veeder! More details in the updated review. This doesn't affect the score I wish I'd given, since as I said I didn't take it into account in my original score.] Cold Iron: 7. The best of the short games. I'm going to guess Eric Eve as the author (though the college whose members he thanks isn't at Oxford — yes, I looked it up). Sentencing Mr Liddell: 7. The game I'm most conflicted about. Hugely ambitious, a lot of emotional power if most of it's unpleasant, but some polish issues and some incomprehensible puzzles take it back to a 7. The Binary: 7. A solid puzzler implemented as a choice-based narrative, with a little more going on besides. I should play the other game in this series, too. Escape from Santaland: 7. Another solid puzzler, well-written and with a lot of stuff implemented. The room-to-interesting-stuff ratio is pretty high, but basically a 7 through and through. Beet the Devil: 7. Another paradigmatic 7, one per deadly sin. Some of the puzzles seem perfect to me, some make no sense to me, you'll probably have a different set. A couple of issues (man do I hate unwinnable states) might push this below Escape from Santaland, but the puppy and the distinctive voice push it back up, and we'd be talking about shades of 7 anyway. Having the walkthrough easily accessible in-game helped, and the linear order was also a good idea (if I have to solve every single puzzle anyway, you may as well have me focus on one at a time). It: 7. Slight but solid, and some interesting things with multiple endings. Six: 7. Much more substantial, and all the bells and whistles should perhaps push it up to an 8, but in the end the gameplay wasn't involving enough for me to rank it higher. I realize that this is partly because it's for kids, but I reserve the right to judge it as a non-kid. I'd like to combine it with It to get the Australian hide-and-seek game of my dreams, which is a dream I didn't know I had. Ted Paladin And The Case Of The Abandoned House: 6. A self-conscious, fourth-wall breaking puzzle box, and the puzzles are clever, but I wish there'd been more to them — especially the last one, which could've been a spectacular tour de force but which was basically a proof of concept. Also one of the puzzles was mistakenly clued, although in a way that didn't waste too much time. Last Day of Summer: 6. The second-best of the short games. Not as evocative as Cold Iron, for me. Keepsake: 6. Might also be the second-best of the short games. I liked the idea, not sure it would be possible to develop it into more than a sketch, a sketch is what it is. Calm: 6. Should be utterly awesome after a leisurely revision. For now, various polish issues keep it below 7 level (am I illegitimately docking it for the game-breaking bug I encountered after more than two hours?) Also, Yoon is right: Don't insult the player in the hint file. Tenth Plague: 6. Short, kind of massively unsubtle with a moral message that perhaps doesn't need to be delivered, didn't involve me emotionally in the way it ought to have for reasons that will be explained in my review. But solid and well put together. Might just be not to my taste. Blind: 5. My review of this was probably too mean; despite a couple unclued interactions it does work as a puzzle game, and apparently there are mutliple ways through in a way that might be interesting. I still don't think the author has really inhabited the perspective of a blind person or a woman, and that's a problem in this game, but that aside there's nothing much wrong with it. Playing Games: 5. This game is there. What writing there is is fine, I enjoyed playing through it, but it's almost aggressively insubstantial. How Suzy Got Her Powers: 5. Short! Contains dubious fire safety lessons, I suspect. The Life (and Deaths) of Doctor M: 5. Objectively may be better than this, but got knocked down to a 6 for annoying gameplay that made me unable to get very far into it in two hours, and then another point off for the factual distortions that I discuss in my review. The Guardian: 5. Another short one. Mostly about moving through large spaces and reading descriptions. The writing is decent but perhaps needs to be awesomer to sustain it, especially given the vagueness of the plot. (See Cold Iron for how adding more detail to both those things can get you two more points.) Cursed: 5. Hugely ambitious, another one I got about halfway through in two hours. As many others have observed, there's far too much prose, but some neat puzzles (more when I review it), and the dialogue section at least helps you through it by bolding the topics. But in the end, the verb-guessing (on timed puzzles!) makes it too hard to play. Also, the hints were sometimes actively unhelpful; I would be in a situation where I knew I needed to do X to Y but couldn't guess the verb, and would dutifully page through the hints, which would would end "Maybe you should do X to Y" and ho for the walkthrough. The Ship of Whimsy: 4. So, so slight. Docked a point for the obnoxious ending. Death of Schlig: 4. Not actually fun to play. Needed to be fun. Andromeda Awakening: 3. The ambition and world-building are commendable, but playing it gave me a blinding headache. Much venting in my review. Awake the Mighty Dread: 3. The polish issues make this pretty much unplayable, since an (apparently) crucial NPC must be reached by interacting with an object that refuses all the obvious ways to interact with it. Professor Frank: 3. Is genial and up-front about how messy it is, but I can't actually recommend it. Vestiges: 1. Problematic in many ways. Gigantic run-on sentence explaining why some games aren't rated: I beta-tested Kerkerkruip and Fan Interference, can't play Dead Hotel on my computer, got booted out of the online server for the Myothian Falcon and never found a block of uninterrupted time to play it all the way through (especially because rumor has it it's pretty long), had a hang-up on the first turn of online play of Return to Camelot, gave up on Luster after a few turns ("these jewels will bring you fame and fortune" is not a good hook — I do all the work, the PC gets the fame and fortune — also, a typo in your blurb doesn't inspire confidence), was turned off Fog Convict by the other reviews (I know this is irresponsible), never went back to Operation Extraction after it turned out to be very complicated (but it's an interesting idea!), and never got back to the revision of the Elfen Maiden after having trouble on my initial playthroughs (kudos for responding to feedback, though the particular revision may have been way too ambitious for an intra-comp update; really I was just hoping for more time for the initial puzzle, which I may have got.) […] is my last batch of reviews for the IFComp! It's not my final thoughts, though, which are here. More reviews are here. And though the comp is over, you can still play the games here! If you need […] Pingback by IFComp Reviews, Part 8 and Last « Saucers of Mud — November 19, 2011 @ 12:09 am
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An MSN in Leadership and Management is a Master of Science in Nursing program that lets students and nurses enhance their nursing education and experience in the field. It is an accredited program recognized by the Commission on Collegiate Nursing Education system. The course is open to registered nurses with a Bachelor's Degree in Nursing or other RNs in different fields. A Masters of Science in Nursing degree is also offered to registered nurses who do not have a baccalaureate degree. All they need to do is to meet general requirements from their previous course. Students under this program will have to complete the MSN and Bachelor's Science in Nursing degree or BSN programs. The MSN course aims to prepare nurses for leadership in a managerial position. leading other nurses, they will also train those under them. Once you finish the course, part of your tasks will involve improving public health programs in communities. If you take this course, you can also participate in research and announcing your latest findings at presentations or through publications and journals. Other elements that you may also touch on are advanced classes in humanities, sciences, and medical theories that support complex nursing programs. You will be in charge of evaluating and applying the delivery of health care to various sectors by creating a working strategy. Your objective will vary depending on the situation of each case. With more and more nurses in the field, the need for a leader and administrator also increases. The MSN program was designed to prepare nurses to handle more complicated and high level duties as a leader. The program also introduces people in the nursing field to new trends and leadership methods applicable in the health care business. You will have to make policy decisions in your health organization which will affect everyone including other nurses, patients, doctors, and the organization as a whole. You will be taught different business functions, finance, and economics during your course of study. You can take this course at a college campus, a health care training facility, or through online classes. Distance learning on the internet is ideal for nurses who are employed. Studying via the Net will allow you to continue working as a nurse while learning an advanced degree in MSN. Online courses will entail the same curriculum as a regular class on campus. A fully registered nurse with an MSN in Nursing Management can become a director of nursing, manager, union leader, legal consultant, or ethicist in the nursing field. You can get hired at hospitals, pharmaceutical companies, insurance companies, or managed care facilities. Your wage and benefits will be much higher than those of an ordinary registered nurse.
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The exhibition Who is the Victor? One fundamental feature of sports matches is the time limitation placed on them by the rules of the sport, which clearly define the beginning and end of the contest. Athletes are much-admired sporting idols, whose exceptional achievements are a result of natural talent, hard work, determination, commitment and bravery. When competing, they often have to overcome not only their own limitations, but also various other obstacles and difficulties. Like individuals in ordinary life, their "victories" are determined by their goals, which in turn are a product of their individual preferences. The leitmotif running through the exhibition "Who is the Victor?" is the concept of the route, a time-defined sequence, a journey through life, a path running from point A (the start) to point B (the finish?). At the core of the exhibition is a projection of Igor Korpaczewski's work depicting the figure of a man (The Timeman, 1998), a runner measuring time. This is the central anchor-point for the multidirectional spatial configuration of the exhibition, which presents a mixture of works in both traditional and new media. The mass sharing of sports events – based on the coexistence of an anonymous mass of individuals all committed to the same cause – greatly intensifies the (co-)experience of victory. Powerful emotional experiences create bonds among people. The feeling of sharing the same cause blurs the boundaries among us. A major factor influencing the intensity of our experience is the extent to which the spectators identify with the athletes. The intense media focus on sports events has accelerated the growth of sport's global popularity – accompanied by a growth in the prosperity of the organizations supporting, sponsoring and organizing sports events. The athletes themselves are becoming a new form of currency. The question "Who is the Victor?" – the central idea of the exhibition – can be answered in countless ways. The answer depends on the context. The victor of what? Between whom? Over what or whom?
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Following several years of discussion and a very close vote, Peoria incorporated on June 7, 1954. County supervisors appointed a seven-member town council to serve the inaugural term—four who had been in favor of incorporation (Charles Brice, Manuel Leyva, F. L. Turner, and Roland Pomeroy) and three against (Don Wagoner, O. M. "Mac" Bradshaw, and Carl Hunt). The new council was sworn in and held its first organizational meeting on June 14, selecting schoolteacher Roland Pomeroy to be the city's first mayor. One year later, the residents of Peoria went to the polls to select the town's first elected officials; returning councilmen Hunt, Kosier, Leyva, and Pomeroy were joined by new members Clarence Meeker, Edmund Tang, and Charles K. Vickrey, who became Peoria's second mayor.
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Davy Kaye MBE (25 March 1916 in London - 3 February 1998, Paradise Island in the Bahamas), born as David Kodeish, was an English comedy actor and entertainer. Born in Mile End Road in the East End of London to Jewish parents Koppel and Dora Kodeish, Kaye was so small at birth that he was not expected to live. As a schoolboy he appeared in amateur revues and shows at his school, making his professional debut at the Mile End Empire in 1935. On the outbreak of the Second World War Kaye tried to join up but was turned down due to his short stature, later telling the story that the medical officer had said, "When we declare war on pygmies - we'll send for you." Instead, he spent the war years entertaining troops at RAF bases, munitions factories and Army camps as well as on BBC radio where he was a regular with such shows as Midday Music Hall and Variety Bandbox. Following the war the 4' 11" tall Kaye toured in his own revues with his then agent Joe Collins, the father of Jackie and Joan Collins in a partnership which lasted for more than thirty years. He played Benny Southstreet in the original 1953 London production of Guys and Dolls at the London Coliseum, and played five different characters in the 1961 Wolf Mankowitz musical Belle (based on the case of Dr Crippen) at the Strand Theatre. From 1954 to 1968 Kaye presented a new show each month at London's Embassy Club, and also starred in Androcles and the Lion and The Bishop's Bonfire at the Mermaid Theatre. He appeared in many films including The Wrong Arm of the Law (1963), Crooks in Cloisters (1964), Those Magnificent Men in Their Flying Machines (1965), Carry On Cowboy (1965), Chitty Chitty Bang Bang (1968), Carry On at Your Convenience (1971) and Alice's Adventures in Wonderland (1972). On television he appeared in Sapphire and Steel. He also appeared in pantomime Kaye's last British television appearance was on the Barrymore Show where he performed his famous One Man Band act. A brash man who was said to be difficult to work with, he nevertheless was rarely out of work and on two occasions the Variety Club of Great Britain gave a lunch in his honour at the Dorchester Hotel in 1985 and 1995 to celebrate his 50th and 60th year in show business respectively, both of which were televised on the BBC.Noted for his charity work, over the years Kaye raised more than one million pounds for a number of charities, including the Bud Flanagan Leukaemia Fund, The Duke of Edinburgh's Award Scheme, the Prince Philip Trust Fund, the Nightingale House home for elderly Jews and the Ealing Jewish Youth Club. He was a Past King Rat of the Grand Order of Water Rats (1984), and later was Preceptor. Kaye was awarded the Badge of Merit and Bar, the highest honour that the Order can award. Kaye was awarded the MBE in Her Majesty The Queen's 1995 New Year Honours for his services to charity. He died in Paradise Island in the Bahamas.
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Q: How to link a pdf file in ePub 3? i'm developing an ePub using Sigil. I have addedd some PDF file in my Misc Folder. Now i've created a link to that file, and everything is working fine with iBooks on my Mac. But on iBooks for iOS7 when i tap the link it load (in overlay) a gray page, is this a bug? Should i use another way for link the PDF? Thanks. A: This is probably an issue with iBooks for mac not really requiring strict ePub code. Many times things that "work" in iBooks for mac aren't actually compliant at all. I can't speak for Sigil directly, but can help with the ePub itself: I am guessing you need to change some things in your .opf file: you need to include the pdf as an item in your manifest AND as a nonlinear page in your spine: , . You should use ePubcheck (https://github.com/IDPF/epubcheck) to make sure you are exporting a valid ePub. If you need a tool to zip/unzip your ePub I would use this: http://www.mobileread.com/forums/showthread.php?t=55681 Good luck!
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Text size: AAA low graphics Parish & Community Mass & Services Music Diary Organ Recitals Service Music Cathedral Pilgrimages CHAPLAIN'S MESSAGE: Time for a rest! In our Gospel this weekend we hear the parable of the Good Samaritan. One of the key features of this story is that when the Priest and then the Levite see the man lying at the side of the road, they rushed past him, whilst the Samaritan traveller, moved with compassion, cared for him and took him to the nearest inn, where he could recover. Many of us today might be like the Priest and Levite, not because we are nasty people, but because we are busy and feel we can't spare the time to stop for too long. London is a busy place; outside the Cathedral we easily get swept up in the crowds hurrying to and from Victoria Station. Everyone is in a rush somewhere for something, with their heads down and a schedule to keep. But in this season of summer and holidays, perhaps this is an important weekend to focus on an important, but far too frequently forgotten teaching of the Church: the importance of rest. In the Compendium of the Social Doctrine of the Catholic Church, there is a section dedicated to 'The dignity of work' and under this a sub-heading 'Rest from work'. This begins: 'Rest from work is a right. As God "rested on the seventh day from all the work which he had done" (Gen 2:2), so too men and women, created in his image, are to enjoy sufficient rest and free time that will allow them to tend to their family, cultural, social and religious life.' (284) Primarily this points to the sanctity of the Sabbath as a day for resting from work, but it has wider implications. We live in a society where work is seen as a central part of our lives - much of our focus each day is on our work - and becomes something we must do above everything else. But here we need to look at the origins of the word 'work' itself. In the ancient world work was a form of 'non-leisure'. In Greek, the word for leisure is schole, and the word for business ascholia, which is the negative of schole. The same is true in Latin. The word for rest or leisure is otium. Its negative, negotium, means business or work. In this summer season as things generally get quieter, let us see rest and leisure as a positive thing in our relationship with God and with each other. Let us remember the need to follow the example of God himself, and stop, spending time looking around us, so that like the Good Samaritan we can truly see what is important. Fr Andrew Gallagher See also: College of Chaplains THIS WEEK'S DIARY Friday 12 July Feria 09.30 Hinsley Room Fitness and Coffee Morning 19.00 Cathedral Hall Charismatic Prayer Group Saturday 13 July Blessed Virgin Mary on Saturday 10.00 Hinsley Room Centering Prayer Group 16.00 Lady Chapel Extraordinary Form Mass Special Collection at the Vigil Mass: Apostleship of the Sea Sunday 14 July 15th SUNDAY IN ORDINARY TIME Special Collection at all Masses: Apostleship of the Sea 09.30-13.30 Cathedral Hall SVP Book Sale 13.00 Cathedral Divine Mercy Prayer Group 16.45 Cathedral Organ Recital: Michael Butterfield (London) 19.45 The Windsor Castle Young Adults' Group Monday 15 July St Bonaventure, Bishop & Doctor 10.00 Hinsley Room Mothers and Toddlers Group 11.30 Hinsley Room Prayer Group 13.30 Clergy House Room 2 Legion of Mary Group 2 18.30 Hinsley Room Christian Meditation Group 18.30 Cathedral Guild of the Blessed Sacrament 19.00 Clergy House Room 2 Studying the Catechism Together Tuesday 16 July Our Lady of Mount Carmel 18.30 Cathedral Guild of St Anthony 10.30am Mass cancelled. Confessions 12.15-1.45pm and 5-6pm only. Thursday 18 July 10.30am Mass cancelled. confession 12.15-1.45pm and 5-6pm only. 18.30 Clergy House Room 2 Legion of Mary Friday 19 July Saturday 20 July 14.30 Cathedral LMS High Mass: Bp Campbell Sunday 21 July SIXTEENTH SUNDAY OF THE YEAR 12.00 Hinsley Room Catholic Grandparents' Association 14.00 Hinsley Room Filipino Club 16.45 Cathedral Organ Recital: Joseph Wicks, Truro Cathedral VOLUNTEERS FOR THE CARDINAL HUME CENTRE Cardinal Hume Centre is seeking new volunteers for their Homework Club and After School Clubs for the Autumn Term in September. Clubs are for local, disadvantaged primary school children and involves helping with maths and English and/or playing and supporting children in arts and crafts, cooking and games. Great opportunity for 16 and 17 year olds but all welcome. Email Ioanna at volunteering@cardinalhumecentre.org.uk. Related links: Email for Cardinal Hume Centre THE PASSAGE GARDEN PARTY - FRIDAY 19TH JULY Please support the excellent work which The Passage does for homeless people in Central London, by attending the annual Garden Party in the beautiful and historic College Garden at Westminster Abbey on Friday 19 July, from 6pm to 8pm. Tickets, at £45 each, include wine, soft drinks, buffet supper and live music. Tickets are available online through Eventbrite: (https://www.eventbrite.co.uk/e/the-passage-garden-party-2019-tickets-59008227196) or from The Passage, St Vincent's Centre, Carlisle Place, London SW1P 1NL. Tel: 020 7592 1856. Email: tickets@passage.org.uk. It will not be possible to purchase tickets at the Abbey. All proceeds are in aid of The Passage. Related links: Link for Tickets Email for Tickets SUMMER EDITION OF OREMUS NOW AVAILABLE The July and August edition of Oremus, the Cathedral Magazine, is now available for collection from the stand at the back of the Cathedral, with the usual interesting mix of articles, information and images. Oremus is free, but your donations in appreciation of it are much appreciated and assist with the costs of publication. It is also available to read on Issuu. Please see below for the link to access a digital copy. Related links: Link for Oremus July and August Edition For parents with children at the end of Year 2 or older, and who would like to make their first communion next year, please collect a form from Clergy House Reception. Details on the course, the expectations of the Cathedral and instructions on returning the forms will be provided with the form. CATHEDRAL SUMMER FAIR - SATURDAY 3RD AUGUST Our annual Summer Fair will be held on Saturday, 3 August from 11am to 3pm in Cathedral Hall, Ambrosden Avenue. Please save the date and come along and support us. There will be the usual range of stalls selling gifts, jewellery, toys, books and much more. We will also have delicious food provided by our Filipino and Nigerian community among others, so no need to eat before you come! There will be a Pimms stall too and music and dancing displays by members of our popular Filipino Club. However, in order to help make the event a success and try to raise funds for the Cathedral, we need all of you to help too. You can do this by donating good quality items for us to sell on the stalls such as unwanted or unused Christmas and birthday presents. Homemade jams and preserves, cakes and handicrafts are always popular and sell well. Plus, please do not forget bottles for the tombola stall. Offers of help on the day would be welcome. Donations may be left at Clergy House, 42 Francis Street, for Mary Maxwell. Raffle tickets are now available! MOTHERS AND TODDLERS GROUP Croissants and Christianity: coffee morning with faith and fellowship for those with bumps, babies and toddlers. Join us on Monday morning from 10am to 11.30am in the Hinsley Room off Morpeth Terrace. We have a cup of tea and chat while children play, enjoying an opportunity to pray the rosary together, share common concerns and lend each other spiritual support in an informal and friendly context, often benefiting from input from one of the Cathedral priests. It is free and runs during term time and occasionally during school holidays. The Hinsley Room is on the left as you walk down Morpeth Terrace to Francis St, accessed via an iron gate and up a path alongside the little garden. SUMMER CHARITY TEA DANCE - SUNDAY 18TH AUGUST The Filipino Club will be holding their Summer Charity Tea Dance on Sunday, 18 August from 2pm to 5pm in Cathedral Hall. There will be dancing all afternoon with light refreshments and a grand raffle draw at the end of the day. Tickets are available at the door. Entrance fee is £5 and Raffle Tickets £1 each. The Club never sells tickets on line so please only buy at the door or from a Club Member. All are welcome. DIOCESAN PILGRIMAGE TO WALSINGHAM - SUNDAY 21ST SEPTEMBER Once again we will be taking part in the Diocesan Pilgrimage to Walsingham. This takes place on Saturday, 21 September. We will be leaving the Cathedral at 6.30am and returning at approximately 7pm. The cost will be £21.00 per adult and £11 per child. To book, please leave the required money, in an envelope clearly marked with your name and contact details, at Clergy House Reception. AMERICAN FRIENDS American taxpayers can receive a US income tax deduction for their contributions to support the work and heritage of the Cathedral by directing their contributions to American Friends of Westminster Cathedral, Inc., a non profit 501(c)(3) Organization (EIN # 13-2983174). They will also enjoy special events and receive newsletters about Cathedral activities. Donations may be made through bequests and charitable trusts. Contact Ms. Una Chang, President, American Friends of Westminster Cathedral, Inc., P.O. Box 92, New York, New York 10185-0092, e-mail UChang1@aol.com Related links: Click here for email EXPOSITION OF THE BLESSED SACRAMENT This takes place in the Blessed Sacrament Chapel every Monday to Friday following the 1.05pm Mass until 4.45pm. © Westminster Cathedral 2019 Registered Charity Number 233699 Site map Credits Glossary Privacy and Legal
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We recognise each school is different - we don't look to impose a corporate style or identity on schools but we do have a common approach to maintaining the highest expectations. We believe our role is to help schools achieve excellence through the provision of support, advice and challenge of the highest quality. We are committed to a collaborative approach to our work, based on a shared understanding of what needs to be done, by whom and by when in order to maximise the impact of our work. The Active Learning Trust seeks to promote a tolerant and informed view of the world and holds no political, cultural or religious affiliations. These core values underpin our commitment to provide the highest quality education for all our pupils so that they can go on to live fulfilling and responsible lives as active citizens. We will always be open and honest in our communication and welcome feedback. We always do what we say we will do. We will strive for excellence and quality in everything we do. Our staff can expect support and advice of the highest quality, clarity about the expectations we have of them and the right and responsibility to share successes and concerns. We believe pupils in schools that are part of the Trust have the right to an excellent education and a responsibility to positively take part in school and community life to the best of their ability. We believe that parents are an important part of a child's education and it is the responsibility of the Trust and schools to engage positively with parents to secure their support to raise attainment. We believe that strong Local Boards, acting as part of the Trust's monitoring and evaluation of progress, are key partners to success. Section 54 of the Modern Slavery Act 2015 requires certain organisations to develop an anti-slavery and human trafficking statement each year. This is the statement for the Active Learning Trust.
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Those who have seen my "Cracking the Code of the 'Native' Learning Experience" presentation are familiar with my theory that we have become a more playful society. We spend our cognitive surplus in more interesting ways than ever before. Here is more evidence, a photo taken down Glenwood Avenue, just minutes after Brenda and I had driven through last Wednesday on our way toward a hotel near the Raleigh-Durham Airport. WRAL.com invited people to playfully add to the photo. You can see a slideshow of the photo manipulations here. This part was not fun. Often, when snow is in the forecast and I'm flying out, I'll stay in a hotel near RDU the night before so that I'm only a shuttle-ride away the next morning. It had only just started snowing when we left the house for what is usually a fifteen minute drive. Shortly after riding and pushing our sedan up and down Glenwood Avenue and seeing the gridlock that had already formed in the in-bound lanes, we decided that she would not be able to drive back home. So we went straight to the airport, parked the car, and set out looking for taxis, one to take her back to Raleigh and one to take me to my hotel. The hotel shuttle had stopped running, as had the contracted airport Lincoln Town Car taxi service. Smaller taxi companies had come to the rescue, older green and yellow and electric red cars and minivans, mostly from Japan and driven by young men with exotic accents. Brenda got one of the early ones, headed for North Hills. I got one of the next ones, delivering folks to airport hotels. After two hours of pushing, both ours and many other cars around us, I was in my room, and after another hour, Brenda had been let off at North Hills, from where she walked the remaining mile+ to the house, and lucky to do so. The next day, I learned that my flight, one of only two leaving RDU that day, had been delayed until 12:00 noon, messing up my connection in Atlanta. Lacking the confidence change my connection on the web (Brenda does that stuff), I called Delta to do the rescheduling for me and I got a new itinerary, keeping the first class seats Brenda had paid extra for out-of-pocket. I took an early yellow and green cab to the airport, planning to spend the morning in the Delta Sky Club. It hadn't occurred to me that the lounge might be closed for the snow. No problem though. We had the rest of the airport to relax in. The plane out of Raleigh, which had been parked there for two days, ended out leaving around 2:00 PM, because they'd waited until nearly noon to start preparing it, as even the engine needed de-icing. Trying to board with a 1st class boarding pass, I was informed that they didn't have me listed in their manifest, that the Delta agent I'd spoken with on the phone had mistakenly canceled that flight. They gave me the last seat left, 16A, right next to a Duck Dynasty-looking fellow with a sleeveless shirt and tattoo on his shoulder that said M-R-Ducks. The part about the tattoo a bit of an exaggeration, but the rest of this is true. Of course my delayed delay out of Raleigh caused me to miss my rescheduled flight, but on landing in Atlanta, a very friendly agent told me that I had already been rebooked on a new flight, leaving in an hour and a half. I walked over to the Delta Ski Club there, only to discover that it was more crowded than the concourse. So I spent 45 minutes in the lobby of the club, talking with Brenda on the phone. The flight on to Louisville was without incident and I was lucky enough to grab a Ford Fusion Titanium to drive over to the hotel. The next day my talks at the Sacred Hearts Campus in Louisville went very well, such a gracious audience, and thankful too. Brenda and I both had been keeping them updated on my adventures of the previous two days. Flying out of Louisville the next day was only slightly complicated by more snow during the night, the slight delay leaving me only ten minutes to get from gate B24 to gate A20 for my connection in Atlanta. I made it, though I'm sure that at my age and size, running all that distance with luggage was not a pretty site. The good news is that every once in a while, I will have a trip like that, where everything that can, does go wrong. And then, I'm charmed for the next 24 months or so. So, may the remainder of my speaking trips be without incident, and leave me with only the best memories of this professional life as a vagabond educator.
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Q: Java Google Text to Speech: Play Reponse, Do not Convert to mp3 I am using the google text-to-speech API and I am trying to figure out how I'd be able to play the google response immediately rather than converting it to a mp3 file public static void TTS(String word) throws IOException { authExplicit(); try ( // Set the text input to be synthesized SynthesisInput input = SynthesisInput.newBuilder().setText(word).build(); // Build the voice request, select the language code ("en-US") and the ssml voice gender // ("neutral") VoiceSelectionParams voice = VoiceSelectionParams.newBuilder() .setLanguageCode("en-US") .setSsmlGender(SsmlVoiceGender.NEUTRAL) .build(); // Select the type of audio file you want returned AudioConfig audioConfig = AudioConfig.newBuilder().setAudioEncoding(AudioEncoding.MP3).build(); // Perform the text-to-speech request on the text input with the selected voice parameters and // audio file type SynthesizeSpeechResponse response = textToSpeechClient.synthesizeSpeech(input, voice, audioConfig); // Get the audio contents from the response ByteString audioContents = response.getAudioContent(); // HERE, I DO NOT WANT TO CONVERT TO MP3. I just want the audio played out..... try (OutputStream out = new FileOutputStream("output.mp3")) { out.write(audioContents.toByteArray()); System.out.println("Audio content written to file \"output.mp3\""); } } } A: i fixed this, i added a jplayer to my dependencies then i replaced then i replaced the mp3 part with this: BufferedInputStream inputStream = new BufferedInputStream(new ByteArrayInputStream(audioContents.toByteArray())); Player player = new Player(inputStream); //player from jplayer player.play();
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Pelagia is a long-time lover of all things video game related. She soon realized that her interests didn't lie only in just playing video games but craved to write and talk about them also. She began writing about video games for various hobby sites and magazines a little over five years ago. During that time she has also taken on various roles in the games community which helped to broaden her field experience.
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Palace Cinemas along with the new Principal Partner of the Italian Film Festival, ST. ALi Coffee, are pleased to finally announce the Melbourne dates for the 2020 programme. Running from 25 November until 9 December, the flagship event will showcase Italian culture, stories and language across Palace Cinemas with COVID Safe practices a top priority. With reduced capacities, industrial air conditioning units – circulating fresh air into the cinema every ten minutes, enforced distancing through allocated seating and increased cleaning of all areas, audiences can enjoy and relax in comfort. Due to restrictions, people are encouraged to book early to avoid disappointment. After the long wait, one opening night just won't do – there will be Opening Night Celebrations across Como, Westgarth and Balwyn Cinemas screening a different Festival highlight at each. Tickets are $35 (or $30 MClub) and include a glass of iL Fiore Prosecco and a Festival Tote Bag filled with goodies. For more information visit: https://www.italianfilmfestival.com.au/films/opening-premiere To celebrate the 20th anniversary – and in honour of the late great Ennio Morricone, one of the world's greatest film composers – the ST. ALi Italian Film Festival will close with Giuseppe Tornatore's MALENA (Malèna) starring Monica Bellucci. With a Campari cocktail on arrival and Connoisseur ice cream – there's no better way to celebrate! The Centrepiece selection for the 2020 programme is Marco Bellocchio's crime drama THE TRAITOR (Il traditore), which was the big winner at Italy's 65th David di Donatello Awards – the country's equivalent of the Oscars. The absorbing film sees Pierfrancesco Favino deliver a powerhouse performance as Tommaso Buscetta, a Sicilian Mafia boss-turned-police informer. There will also be two Special Presentations this year: Ferzan Ozpetek's new film THE GODDESS OF FORTUNE (La dea fortuna), featuring an all-star cast including Stefano Accorsi, Edoardo Leo and Jasmine Trinca. The second Special Presentation screening is MARTIN EDEN, by acclaimed writer and director Pietro Marcello. The award-winning drama provocatively transports Jack London's 1909 novel about a self-taught and outspoken writer to a pivotal moment in Italy's pre-war history. The programme also comprises of two films to share with your family. For kids fifteen years and older is MY BROTHER CHASES DINOSAURS (Mio fratello rincorre i dinosauri). Inspired by a true story, this is a joyous and poignant film about the fear of being judged. And for the whole family, THE MOST BEAUTIFUL DAY IN THE WORLD (Il giorno più bello del mondo) – a modern-day fairy tale in which a down on his luck theatre manager receives a strange inheritance – the custody of two children, and discovers that one of them has amazing telekinetic powers. Other highlights for the 2020 ST. ALi Italian Film Festival include: 7 HOURS TO WIN YOUR HEART (7 ore per farti innamorare) about a desperate journalist who enlists the aid of a seduction expert to regain his ex-girlfriend in a fun Neapolitan romantic comedy starring Giampaolo Morelli and Serena Rossi. BAD TALES (Favolacce), set in a southern suburb of Rome and starring Cannes award-winner Elio Germano, this dark tale sees tensions unfold in a small community during a sweltering summer. FEEL YOUR MEMORIES (Tornare), a captivating psychological drama which follows a woman returning to her childhood home in 1990s Naples. Featuring a stellar performance from Giovanna Mezzogiorno. GOLDEN MEN (Gli uomini d'oro), a crime comedy starring Fabio De Luigi, Edoardo Leo and Giampaolo Morelli in which a group of desperate men in Turin attempt an armoured truck robbery. HAMMAMET recounts the last year of controversial politician Bettino Craxi's life as he lived in exile following corruption charges and features an astonishing performance from Pierfrancesco Favino. I HATE SUMMER (Odio l'estate) sees much-loved Italian comedians Aldo, Giovanni and Giacomo star in an amusing story of friendship in which three families accidentally book the same holiday rental. LETSCLEANAPP (TuttAPPosto) – featuring hilarious performances by Luca Zingaretti and Roberto Lipari, this comedy sees a student upending favouritism and corruption in his university with an app for students to rate their professors. ONCE UPON A TIME…IN BETHLEHEM (Il primo Natale) sees the famous comedy duo Ficarra and Picone star as a thief and a priest who are magically transported to year zero, Palestine, where they'll have to make sure that the birth of Jesus will follow its course. ORDINARY JUSTICE (Palazzo di giustiziaI) is a quietly impactful drama from newcomer Chiara Bellosi, which examines the emotions behind the legal machinery at work in the courtroom following an attempted armed robbery. SAY IT LOUD (Cambio tutto), a new comedy from Guido Chiesa (director of Let Me Introduce You to Sofia) which follows one woman's quest to gain control over her life. THE BIG STEP (Il grande passo), a bittersweet tale of brotherhood, and believing in your dream, no matter how far-fetched it may seem featuring Giuseppe Battiston and Stefano Fresi. ALL TICKETS NOW ON SALE. For more information visit: www.italianfilmfestival.com.au Italian Film Festival Coffees & style Father's Day gift guide Coffees & style Valentine's Day Gift Guide: For Him A creative way to Gift with Sarah Urban A guide to the best Father's Day gifts and dining experiences
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How to Contact Sir Appan Parsu K.R. Out Of Character Info: This site is the character platform of Sir Appan, who exists only in the Star Wars universe of the SWCombine. To interact with this character, either in game or in Written Role-Play you must be a member of the SWC. Sir Appan is a man who is on a constant move, therefore he is not the most easiest of sentient beings to track down and speak too. There are only one way in which you can communicate with Sir Appan, the holonet.
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Проховицкий замок (, ) — замок в городе Проховице Легницкого повята Нижнесилезского воеводства в Польше. История Город, расположенный на броде через реку Качаву на пути из Вроцлава в Глогув, вероятно, был основан легницким паладином Ико Мироновичем в 1259 году. Примерно с 1400 года городом начал владеть род Зедлицев. Ее представитель, Отто фон Зедлиц, построил на месте предыдущего деревянного замка каменный, который вместе с башней и северным крылом образует сердцевину нынешнего комплекса. После 1562 года замком владели фельдмаршал Ганс фон Опперсдорф и Фабиан Шёнайх. Тогда было построено восточное крыло и южные ворота. После 1594 года Проховицы были резиденцией легницких князей. Замок был сильно поврежден в 1642 году, во время Тридцатилетней войны. Его восстановили по указанию княгини Анны Софии Легницкой в 1658 году. После угасания линии легницких князей в 1675 году, замок перешел во владения императора Священной Римской империи. После 1820 года замок вновь оказался в частной собственности. В 1835 году графом был заложен ландшафтный парк рядом с замком. Очередной владелец замка граф Курт фон Страхвиц начал в 1905 году его реновацию. В конце Второй мировой войны замок был поврежден и впоследствии отстроен. С 1990 года он находится в частной собственности. После очередной смены собственника замок был снова восстановлен. Архитектура Комплекс состоит из трех параллельных частей здания, которые были соединены между собой раздробленным восточным крылом. С южной стороны находится брама, которая является главным въездом в замок. Замковая готическая башня походит еще с 1422 года. Смежная средняя часть здания датируется XVI-м веком. Во внутренний двор замка ведет портал с Атлантом и кариатидой. Древнейшим фрагментом замка является его северное крыло. Галерея Литература Arne Franke (red.): Kleine Kulturgeschichte der schlesischen Schlösser. Band 1. Bergstadtverlag Wilhelm Gottlieb Korn, 2015, S. 99-100. Замки Польши
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Explore the art and daily life of one of the world's most enduring civilizations! Use an exciting collection of objects, from scholar's writing supplies to a graphic novel to a 12-foot-long reproduction of a classic Chinese scroll painting, to learn about history and empathy. Note: This box was created to complement The Field Museum's Cyrus Tang Hall of China, but if your class can't make it to the museum (or to the website for a virtual tour), it stands on its own. Examine these tiny replications of a typical western gold mine and you'll discover the complicated processes and machinery used to harvest this valuable metal. Learn More Dive into the difficult underground world of coal mining. Complete with tiny workers and machinery, this model exhibits the ways in which we locate and harvest this all-important fuel. Learn More Prance into the world of the deer, one of our most frequent connections to the natural world. Urban expansion has created the need, however, for drastic measures to keep the numbers of these abundant animals in check. Witness a few of the ways we protect our land when deer run rampant. Learn More DNA is the thread that connects all life on Earth, from microscopic bacteria, to mushrooms, to humans. Explore DNA and learn how scientists today are using DNA research to expand what we know about life on our planet. Learn More Dive into the fascinating world of chocolate! Experience the ecological, biological and commercial importance of this treat, with a history dating back to the ancient Maya. Learn More Soothe yourself with the medicinally important leaves of the witch hazel shrub, a secret salve of the Native Americans have been using for centuries. Fresh leaves and twigs provide an astringent lotion for bruises and wounds, and the dried leaves are known to produce a valuable extract used in internal medicine. Learn More Follow a wheat stalk from crop field to sandwich bread in its complicated manufacturing process. Sifting, scouring, brushing and milling are all a part of turning wheat into bran oats, germ, gluten, and flour. Learn More Follow the climbing vanilla vine through its tropical habitat. A member of the orchid family, the bean of the vanilla plant has been used for centuries in Central and South America. Learn More Tea comes from the young leaves of a tea plant, a shrub cultivated in India, China, Japan, and other countries. Take a look at a sprig from this beautiful shrub, and see the many colors and textures of the various types of tea it is used to make. Learn about the process that can turn one plant into so many products! Learn More Grade Band Pre K to 2nd (46) 3rd to 5th (62) 6th to 8th (62) 9th to 12th (58)
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Atlus has released an Etrian Odyssey X trailer titled "Adventurers of High Lagaard" introducing the Gunner, War Magus, and Highlander classes. These classes represent Etrian Odyssey II: Heroes of Lagaard. The "Highlander" and "Prince / Princess" classes have been added to the official website's "JOB" page. The previous classes trailer was "Adventurers of Etria", representing the first Etrian Odyssey.
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BIOMET SOLUTIONS Health at molecular basis How zinc supplementation prevents Viral replication in covid-19 patients May 1, 2022 / Covid-19 is a systemic disease that affects the lungs and multiple organs and tissues. It is transmitted, rapidly from one person to another in close proximity, through contact with virus laden aerosols discharged in coughs and sneezes. Most affected patients die as a result of acute respiratory distress syndrome. There are several variants of Covid-19, but the Alpha, Delta, and Omicron variants are most widely spread with severe health breakdown. Symptoms Of Covid-19 The symptoms of covid-19 are similar to those of normal cold and flu. They are: High temperature or chills Continuous cough Change in the sense of smell and taste Short breath Feeling of tiredness Headache and… BIOMET 1 Comment Role of HBx protein in hepatocellular carcinoma (HCC) Arachidonic acid metabolism pathway Benefits of Zinc in Sexual Functions What is Zinc? Zinc, though beneficial for men's sexual health, is a chemical element with an atomic number 30 and represented by the symbol, Zn. It is slightly brittle at room temperature and has a silvery-grayish appearance when oxidation is removed. In the periodic table, zinc is the first element in the 12th group and in the 4th period. It possesses similar characteristic with magnesium; both elements exhibit one normal oxidation state, only (+2) and are similar in size. It should be noted that Zinc is the 24th most abundant element in Earth's crust and has five stable isotopes. The common Zinc ore being Sphalerite, a zinc sulfide mineral. Despite… BIOMET 2 Comments Cajanol: The role of phytoestrogen in cancer cells Covid-19 Spike protein: structure and functions. The Functions of Zinc in Immune System Zinc is an essential macronutrient, which play a crucial role in multiple cellular functions, including immune cell signaling. In zinc dyshomeostasis, which includes zinc deficiency, there are impairments in several cellular and organ function including overall immune function and increased susceptibility to infection. This shows that zinc cannot be overlooked in immune system and other cellular processes. Some of the problems associated with zinc deficiency are growth retardation, neurological disorder, immune dysfunction and Acrodermatitis enteropathica, a metabolic disorder. Zinc Transporters Zinc coordinates its signaling through two families of zinc transporters and metallothiones. The two families of zinc transporters are: The Solute-linked carrier 39 (SLC39A or ZIP) family of zinc… Folic Acid Benefits For Men: Why You Should Eat Folate Rich Foods Monkeypox Virus Infection Zinc (Zn) is a chemical element, which is an essential macronutrient for basic cell activities such as cell growth, cell differentiation and survival. It is found in high concentration in the red blood cells as an essential part of the enzyme, carbonic anhydrase, which promotes many reactions relating to carbon dioxide metabolism. In the pancreas, Zn aid in the production, secretion and storage of insulin. The cellular functions of zinc can be found in the regulation, activation and expression of biological molecules such as transcription factors, enzymes, adapters, channels and growth factors, along with their receptors. When Zn is deficient or excessively absorbed, it disrupts Zn homeostasis and growth, morphogenesis… Anti-aging Properties of Alpine Rose Matrix Metalloproteinases (MMPs)
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from TECHNOLOGY NETWORKS The Right Mouse Is Key for Huntington's Drug Development News Dec 12, 2019 | Original story from IOS Press Credit: Photo by Yunu Dinata on Unsplash https://unsplash.com/@yunu06_dinata Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies. Their findings are published in the Journal of Huntington's Disease. "Patients with HD commonly suffer from debilitating mood disorders, but developing disease-modifying drugs for HD has proved to be extremely challenging," explained lead investigator Robert M. Friedlander, MD, MA, Chair and Walter E. Dandy Professor of Neurosurgery and Neurobiology at University of Pittsburgh School of Medicine, and Neuroapoptosis Laboratory, Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA. "One reason could be that we are not using the right animal models in research." The amount of serotonin transporter (SERT), a molecule commonly targeted by medications to regulate mood, is increased in the brain of patients with HD. Investigators compared SERT levels in normal and Huntington's brain tissue samples, as well as brain tissues from two different mouse models of the disease. They found that the amount of SERT was increased in HD patients compared with controls, and that this finding was modeled in one type of mouse model, but not another. Investigators found that HD patients have significantly increased SERT protein levels in one region of the brain, the striatum, which coordinates multiple aspects of cognition, but not in the globus pallidus, which regulates voluntary movement. The neurodegenerative process commences in and most severely affects the striatum, affecting other brain regions as the disease progresses. This likely has an impact on the prevalent mood disorder in HD. Increased SERT levels are demonstrated in the brain of CAG140 mice, a full-length knock-in mouse model of the disease, but not in the striatum of the R6/2 fragment murine model of the disease. Based on this parameter, the investigators recommend that the CAG140 huntingtin knock-in mouse model is more suitable than the R6/2 model for the study of serotonergic pathway pathology in HD. This is important because researchers should be sure to use the appropriate disease models when designing experiments. However, they conclude, there is no mouse model that completely recapitulates human HD. Each mouse model has its strengths and weaknesses and it is therefore important to use complementary models and always relate to known findings in human tissue. "We found that not all HD mouse models are the same, so researchers need to use the models that are most relevant to their studies," commented Dr. Friedlander. "This advance in our understanding of the mood-related symptoms in HD is key to designing treatments that will improve the quality of life for patients with this disease." HD is a fatal genetic neurodegenerative disease characterized by atrophy of certain regions of the brain. It causes the progressive breakdown of nerve cells in the brain. HD patients experience behavioral changes and uncontrolled movements. Symptoms include personality changes, mood swings and depression, forgetfulness and impaired judgment, and unsteady gait and involuntary movements (chorea). Every child of an HD parent has a fifty percent chance of inheriting the gene. Patients usually survive ten to twenty years after diagnosis. Reference: He, Y., Suofu, Y., Yablonska, S., Wang, X., Larkin, T. M., Kim, J., … Friedlander, R. M. (2019). Increased Serotonin Transporter Expression in Huntington's Disease Patients Is Not Consistently Replicated in Murine Models. Journal of Huntington's Disease, 8(4), 449–457. https://doi.org/10.3233/JHD-180318 This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source. Doubt Cast on the Use of Viagra for Fetal Therapy University of Manchester scientists investigating a possible treatment for fetal growth restriction (FGR), a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra. Widely Consumed Oil Is Linked With Genetic Changes in the Brain New UC Riverside research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer's disease, anxiety, and depression. Why Have Multiple Sclerosis Drug Costs Tripled in Seven Years? The cost of prescriptions for multiple sclerosis (MS) in the US drugs nearly tripled over seven years, and the introduction of a generic version of one of the most common drugs had little overall effect on prices, according to a new study . Drug Discovery Neuroscience Sourcing Fresh Human Blood Products for Research Ligand-Receptor Binding Kinetics on the PHERAstar® Microplate Reader Exploring Methods for Host Cell Protein Analysis PAA to Showcase New Laboratory Automation Solutions at SLAS2020 Can Blue Light Help Heal Traumatic Brain Injury? News Jan 17, 2020 Unraveling Parkinson's Protein Insights How Alcohol Addiction – and Abstinence – Remodel the Brain A Bigger Hippocampus Doesn't Mean Better Memory How Does the Brain Know When It's Hungry?
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HomeLatest NewsRegionsAsia LeadsRZD to purchase 1000 electric locomotives RZD to purchase 1000 electric locomotives Russian Railways intends to purchase 1000 new electric locomotives over the next three years, valuated at EUR 2 billion. In addition, the company will expand its Lastochka existing fleet from the current 183 trains in service increasing to 270 by 2021. The two projects are part of company's wider electrification and reduction of emissions strategy. The new electric locomotives and increasing the number of Lastochka trains form the pillar of the electrification process. RZD is focused on the electrification of its busiest lines and on the decommissioning of diesel locomotives. Currently, more than half of the 85,500km Russian rail network is electrified and more than 85% of all rail passenger journeys in Russia take place on the electric network. With rising passenger journeys out of urban centres towards surrounding regions, Russian Railways has been building out its electrified network and rolling stock to offer transport at the best combination of speed and price, and with the lowest possible carbon impact. Journeys on high-traffic routes are forecast to rise, and RZD projects should help to attract travellers away from cars and buses, and onto electrified trains. Railway travel already offers significant advantages over road and air travel in terms of CO2 emissions and resource consumption. The Lastochka trains will improve this performance, achieving CO2 emissions typically by 3.5 times lower than road transport and almost by 10 times lower than air transport. Russian Railways' investment programme for 2018-2025 has a total value of EUR 100 billion.
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A low cost way to make a powerful statement. Long Beach full service business printing. From custom commercial business signs and banners, advertising products, trade show booths, box signs, channel letters, neon, custom graphics and logos to printing flyers, business cards, t shirts and more. As you walk around Downtown you'll see our work everywhere. Gator Board is a material similar to Foam Board with a dense, durable foam sandwiched between two smooth, moisture-resistant layers that help form a rigid board that is resistant to bending, warping and denting. Gator Board's exceptionally rigid surface and quality make it the mounting board of choice for photographers. It makes an ideal backing for paper or vinyl printed products that are lighter than Sintra Board, but tougher than conventional Foam Board. Foam Board is a thin piece of foam sandwiched between two smooth sheets of paper making a lightweight, rigid product. Foam Board Posters are perfect for a wide variety of purchase and artwork displays. The surface is excellent for printing, die cutting, and mounting photos, prints and artwork. We can print your completed design or help you design your own unique custom creation. We'll help you learn about business printing and basics. Corplast Signs are perfect for inexpensive outdoor advertising such as an upcoming garage sale, real estate signs or election campaigns. Corplast is extremely durable because it is waterproof and resistant to stains and most chemicals. An "H" frame stake will hold up to 1/4" thick sign substrates. H-Frame stakes are the perfect accessory for Corplast corrugated sheeting. They fit right into the flutes to make a rigid sign which can easily be placed in the ground. Custom aluminum metal signs have a perfectly smooth finish and project a first class image. Aluminum is strong, light-weight and among the most durable of all sign materials as well as cost effective. Aluminum is in high demand for its unbeatable qualities. Plus, a custom aluminum sign can never rot or deteriorate like a standard wooden sign. Sintra Board is a durable PVS sheet material and is ideal for strong, long-lasting indoor or outdoor displays because of it's UV resistant, lightweight and moisture-resistant characteristics. Sintra Board Posters are great for exhibit booths, models, displays, indoor/outdoor signs and photo mounting. Zepp Signs caters to malls with specialized signage for all needs. We are experts at standard sized mall posters, identity logos and entranceways. Great for food courts, barricades, window clings, banners, menu systems and more! Styrene is a smooth, lightweight, plastic sheet material that is less than 1/16" thick. Styrene is not affected by variations in moisture content, making it stable, flat and warp free. It can be used indoor or outdoor, but is not recommended for long-time exposure to the sun. This material is perfect for long-lasting indoor display of your custom graphics in bold vibrant colors. We offer a gloss or matte finish for extra protection and outstanding visual performance. Ready to get started! We are the best in exploring all the possible solutions you have. Backlit Film is a thin, clear vinyl material that is ideal for displays that will be seen during the day or at night. Zepp Signs prints your advertisement directly on this film with bright vibrant colors. Soft lights are then used behind the film in applications such as mall displays or mobile backlit advertising for a dynamic way of displaying your graphic designs.
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Robert Smithson did not go to college. As a New Jersey teenager, he commuted to some classes at Manhattan's Art Students League and the Brooklyn Museum, but after high school he did not enroll in art school. He joined the Army Reserves instead, then bummed around the United States and Mexico. Today, when it is unlikely that an artist would emerge into prominence without a university degree or the network of affiliations developed in art school, Smithson's lack of formal training as an artist manages to startle. The surprise is even greater when measured against a claim in the catalog to the much-anticipated retrospective of Smithson's powerful work, which opened Sunday at the Museum of Contemporary Art. Whether one agrees with the assertion that "no other postwar American artist can be said to be as influential" as he, the effect his art and writing have had on art in the last 30 years is immense. That influence partly extends to his important peers. Smithson (1938-73), whose death in a plane crash at age 35 stunned the art world, was a pivotal member of a generation that included Richard Serra, Eva Hesse and Carl Andre. Yet, recently emerged artists such as Sam Durant, Renee Green, Tacita Dean and Matthew Coolidge (with the collective known as the Center for Land Use Interpretation), all of whom were too young to have witnessed Smithson's brief but blazing evolution first-hand, have also built on his precedent. I mention this aspect of Smithson's biography for a particular reason, which has to do with his work. He's widely revered as a pioneer of Earthworks (or Land Art), in which sculptural manipulation of the wilderness landscape creates art with imperceptible boundaries and that cannot be contained within a museum or gallery. But the retrospective shows something slightly different. Above all else, Smithson's art privileges perceptual experience. Literate, astute in its knowledge of complex scientific and mathematical theorems, shrewd and often witty, his work nevertheless positions itself as a catalyst to a fascinating perceptual experience. The move away from the gallery and into the landscape was important, because a sludge of expectations, habits, rules and assumptions had settled around vanguard American art. Smithson was enamored of Abstract Expressionist painting of the 1940s and 1950s, and the work by which he's known today drank deeply from the well of Jackson Pollock. But the exceptional creative ferment of the 1960s was partly fueled by an aesthetic sense of dull conformity, coupled with the social and political constraint of the era. Smithson's genius was to make liberating objects (and environments) that busted up those impediments, while also directly asserting the awesome power of inertia. The exhibition, organized and artfully installed by guest curator Eugenie Tsai with MOCA curator Connie Butler, includes a strong selection of 10 of Smithson's gallery pieces from 1968 and 1969 -- the famous "nonsites" and "mirror displacements." Sand, stones, shells, cinders, rock salt and other natural materials gathered from outdoor sites -- often remote and desolate or evocative of industrial slag -- are stacked in steel bins, paired with topographical maps and piled around sheets of mirror, holding them in precarious geometric configurations. Widely shown and discussed, and seen by many more people than the Earthworks Smithson made in remote corners of Utah, Texas and elsewhere, they remain a signal achievement. The show's revelation, however, is the painted metal and mirrored wall reliefs. They date from just before the potent nonsites and the classic Earthworks -- such as 1970's famous "Spiral Jetty," a 1,500-foot coil of rock in the apocalyptic environment of Great Salt Lake. Although I've seen most of the painted reliefs and floor sculptures before, I was unprepared for how fresh and invigorating they look here. They radiate a colorful whimsy that is frankly Pop. Take the untitled 1964 relief whose metal frame unfolds across the wall like an enormous pleated fan (it's more than 6 feet wide). The frame is painted golden yellow, while the mirrored panels are a bright teal-blue. The long, skinny, four-sided pyramids in Day-Glo hues jut out from the wall, like disco decor. The relief might be abstract, but the vibrant color is as striking as a glamorous portrait of Marilyn Monroe by Smithson's friend Andy Warhol. The sculpture is Minimalist bling-bling. Its faceted form recalls a crystal, but the emphasis on industrial manufacture and unnatural color means we've entered the land of rhinestones, not diamonds. Stand before the mirrored relief and a strange thing happens. The mirrors don't reflect you. Angled, the mirrors instead reflect the ceiling, floor and surrounding gallery walls, sucking the space of your peripheral vision into your direct line of sight. The flat plane of the wall on which the mirrored relief hangs seems to splinter and dissolve. In the vaporous drip-paintings that Smithson loved, Pollock invented "all-over composition," in which shapes are dispersed equally across the surface plane. In Smithson's relief, the all-over composition goes even further, expanding outside the frame to encompass the entire environment within which the work of art is installed. There is no center and no periphery to this composition -- just a continuous, fractured field, through which your surreptitiously heightened perceptions move. You find yourself acutely aware of exploring your relationship to a physical object, experienced in real time and tangible space. With Monroe, Warhol converted Picasso's and De Kooning's voluptuous paintings of women into an all-American Pop icon. Smithson's faceted reliefs did the same for Modern art's obsession with crystalline form. For 50 years, the luminous, transparent crystal had represented Modern utopian ideals of clarity, purity and essential truth. Smithson's achievement arose from submitting the European-inspired rhetoric of New York School paintings and sculpture to the vernacular of American life. Hey -- he was a kid from New Jersey, after all. There would be no glittery Manhattan without the grim industrial landscape of the Garden State. "A Tour of the Monuments of Passaic," a breathtaking (and funny) 1967 essay with pictures that Smithson produced for Artforum magazine, chronicles a journey home to his birthplace. The monuments he encountered there included an old trestle bridge, pipes spewing sewage into a river, a rusted oil derrick, concrete highway abutments and a used-car lot -- all jauntily described. "Has Passaic replaced Rome as the Eternal City?" he wrote, like some self-appointed aristocrat taking a New World Grand Tour. Ashes to ashes and dust to dust. If Passaic is the site of the inglorious ruins produced by industrial society, to which everything eventually returns, then New York is its nonsite, a boxed landscape where cultural representations of the world are gathered in art galleries and museums. The sculptural nonsites and mirror displacements that Smithson began to make brought this poetic meditation to a ringing climax. One small disappointment with the MOCA retrospective is that the first and last nonsites he made are not included, so the trajectory of this pivotal body of work is incomplete. Smithson's mature career was brief -- barely nine years, from 1964 to 1973 -- but his fecund brain produced a lot of work in the form of drawings, photographs, project proposals and films. Three-quarters of the 160 objects on view are works on paper. A second fascinating aspect of the show is the inclusion of rarely seen paintings and drawings that date from even earlier than the reliefs, before 1964. Artistically they're prosaic, but here they provide an unexpected insight into his later, more influential work. They include a number of Expressionist images related to the life of Jesus and St. John the Baptist (Smithson was raised Catholic). The curators have installed them near the middle of the show, in a gallery that also includes drawings of his most prominent Earthworks. The juxtaposition is a shock. A lot has been written about the artist's attraction to spirals, pyramids, mounds, ziggurats and other primal forms associated with antiquity. Until now, though, I had never connected those Earthworks' forms to anything like these drawings and paintings. Religious iconography such as "Man of Sorrow" or "Jesus Mocked" is concerned with archetypal states of being. So, in a secular way, is Abstract Expressionist painting. The primal forms of Smithson's Earthworks gain new resonance. Not to mention the pleated yellow frame of that bling-bling wall relief, which suddenly recalls the gilded corona of a Baroque altarpiece. Wandering in the desert, where the greatest Earthworks are often found, does have a certain biblical elan. For the exhibition, Smithson's widow, sculptor Nancy Holt, has just completed a wonderful Super-8 film (begun in 1968) in which the two young artists joined fellow sculptor Michael Heizer on a desert romp about 65 miles north of Bishop, Calif., in the ancient landscape around Mono Lake. Cinders from the site, one of the oldest lakes in North America, were used to make a nonsite in the show. Forget about divine revelations, though. The vibrant immediacy of vernacular experience is, as always, more to the point. The lush soundtrack features a romantic score by Michel Legrand, cribbed from "Bay of Angels," a 1963 Jacques Demy film starring a bleached-blond Jeanne Moreau. That movie tells the story of a gambler who coaxes a friend to a Cote d'Azur casino, where he meets a Monroe-type movie star. Their love affair plays out against the volatile spinning of the roulette wheel. The Mono Lake trio are fresh from the gambling palaces of Las Vegas. They cavort along the edge of the saltwater, chasing swarms of flies. Smithson's voice-over narration about the ravaged site sounds suitably authoritative, but it actually comes from a local tourist brochure. History bleeds into mythology. Almost a century before, in the decades when continental expansion was coming to an end, artists ventured into Yosemite Valley just west of Mono Lake, naturalizing in their paintings a rapacious doctrine of Manifest Destiny. Think of Yosemite as the glittering Manhattan to Mono Lake's grim New Jersey. Smithson's Western wilderness hasn't a trace of Utopia, but it sure looks like a lot of fun. Where: Museum of Contemporary Art, 250 S. Grand Ave. When: 11 a.m. to 5 p.m. Mondays and Fridays, 11 a.m. to 8 p.m. Thursdays, 11 a.m. to 6 p.m. Saturdays and Sundays.
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Ellwood Crankshaft Group utilizes various techniques to surface harden the crankshafts based on product application and customer specification. A new induction hardener will supplement the flow of production along with five large vertical gas nitriding vessels. The investment and technological advances in the business continue to widen the gap of capabilities and service between Ellwood Crankshaft Group and our competitors.
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Voters will now decide on an amendment to expand charter schools after the measure made it through the state House. For months, the Georgia Legislature has served as a key battleground for the charter-schools debate. Now the fight goes to the voters, who will ultimately decide the fate of a constitutional amendment to allow "state-chartered" schools over the objection of local school boards. The measure, which creates a state charter-school commission to approve charters rejected by local school boards, became a major focal point of the legislative session. Wausau Daily Herald broke down the thousands of dollars that lobbyists spent on meals and gifts to woo state lawmakers to their side, which verge on the ridiculous. For instance, the American Federation for Children, advocating for the measure, "paid $75 for frames for photos of state lawmakers with former Braves pitcher John Smoltz." The House passed the measure in March, but it stalled in the Senate. It was only on Monday that four Democrats chose to support the measure, giving it more than the two-thirds it needed. Now advocates and opponents will try to convince voters to support them. Voters can expect a complete bombardment. But like almost all the discussions about charter schools, the debate seems to center on two key questions—are charters inherently more innovative than traditional schools, and where will the funding for them come from? Funding became the central question in the legislative debate. The legislature created a similar commission in 2008, until the state Supreme Court knocked it down as unconstitutional last May, largely because the old measure withheld state aid to school districts and instead sent that money to charter schools to make up for the lack of local tax dollars (The Newnan Times-Herald has a nice recap of the situation). This time around, to get the necessary support in both chambers, authors altered the measure to guarantee that it would not have an impact on local funding. The move got some Democrats behind the bill, but many opponents remain unconvinced. After all, the money has to come from somewhere, and these are lean times for state revenues. Some worry that despite the change to the bill, there's still enough wiggle room in the language to divert funds. The concern about funding connects strongly to suspicions around charter schools more broadly. Senate Republicans killed an amendment that would have required the charters to be nonprofits. That means for-profit schools will compete for state dollars—leaving skeptics worried that traditional public schools could lose out to those trying to make money. Meanwhile, local school boards have significantly less say in the fate of their districts. The trouble is that there's an increasing lack of evidence that charter schools as a whole are really doing things any better than public schools. Ironically, that's particularly true in Georgia, where the state Department of Education came out with an in-depth report last week showing that "the general trend of Georgia charter school performance mirrors the trend of traditional public school performance." Many expected the report's findings would cool down support for the charter measure. Instead, a week after its release, the Senate passed it. In November, we'll see if state voters follow suit.
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TRANSCRIPT OF A PRESS BRIEFING ON THE GLOBAL FINANCIAL STABILITY REPORT / INTERNATIONAL MONETARY FUND | Etiquetas: Banks And Banking, Economics, Emerging Markets, Financial Markets, IMF, Shadow Banking, World Economic And Political Transcript of a Press Briefing on the Global Financial Stability Report JOSÉ VIÑALS IMF Financial Counsellor and Director of Monetary and Capital Markets Department PETER DATTELS Deputy Director, Monetary and Capital Markets Department Division Chief, Monetary and Capital Markets Department ANDREA MAECHLER Deputy Division Chief, Monetary and Capital Markets Department OLGA STANKOVA Senior Communications Officer, Communications Department Ms. Stankova: Good morning everybody. Good afternoon to those who are joining us from afar. Welcome to the press conference on the release of Chapter 1 of the Global Financial Stability Report, which is entitled, "Risk Taking, Liquidity, and Shadow Banking: Curbing Excess While Promoting Growth." Let me introduce the speakers today. In the center, we have José Viñals, the Financial Counselor of the IMF and Director of the Monetary and Capital Markets Department. Immediately to my right, is Peter Dattels, Deputy Director in the MCM department. To Mr. Viñals's right is Andrea Maechler, Deputy Division Chief in the Global Markets Analysis Division of the same department. And to her right is Matthew Jones, Chief of the Global Markets Analysis Division of the MCM Department of the Fund. An administrative announcement on the interpretation channels today. Channel 1 is English, channel 2 is Spanish, channel 3 is French, channel 4 Arabic and channel 5 Chinese. With that, I will pass the microphone to Mr. Viñals for his opening remarks, and then we will take your questions. Over to you, José. Mr. Viñals: Good morning to all of you, and welcome once more to the presentation of the Global Financial Stability Report. In this edition that we are presenting today there are three key messages that I want to pass on to you. The first one is that the world is facing a new global imbalance, an imbalance between not enough economic risk taking of the sort you like, in terms of consumption, investment, to promote growth, but increasing excesses in financial risk taking which may undermine stability going forward. The second message is that banks are now much safer, but many banks still lack the vigor to strongly support the economic recovery by providing sufficient credit in the future. At the same time, risks are shifting to the shadow banking in the form of rising market and liquidity risks and, if left unaddressed, these risks could compromise stability going forward. The final key message is that in order to address these new global imbalances, policymakers in different parts of the world need to engage in a new balancing act, a balancing act to promote economic risk taking by improving the transmission of monetary policy to the real economy, and address financial excesses through micro prudential and macroprudential policies. So after having laid out the key messages, let me go in turn into developing each of these issues. First, on the imbalance between economic and financial risk taking. It is now more than six years since the beginning of the global financial crisis, and the economic recovery continues relying heavily on accommodative monetary policies in advanced economies. This has helped growth by encouraging economic risk taking in the form of higher investment and employment by firms and higher consumption by households. But the impact has been too limited and uneven. Things look better in the United States and Japan, but less so in Europe and in emerging markets. Yesterday you had an analysis of these issues during the presentation of the World Economic Outlook. At the same time, prolonged monetary easing has encouraged the buildup of certain excesses in financial risk taking. This has been reflected in elevated asset prices across a range of financial assets; credit spreads which are now too low to compensate for the full risks in some market segments; and until recently record low volatility. All of these are clear indications that investors are indeed complacent. What is unprecedented is that these developments in financial markets have occurred at the same time across a broad range of assets and also across many countries. On top of that, let me also signal that in emerging markets there has been a continuation of the buildup of debt on the part of corporates, an issue that we examine in detail in the last issue of the GFSR. So, how do we address these policy challenges? For that I would like now to go into what is going on with banks and what is going on with nonbanks. So let me start with banks. There we have good news and not-so-good news. The good news is that banks are now much safer than they used to be a few years back. Now they have much stronger capital, much stronger liquidity, and they're supported by much stronger regulatory frameworks. I think this is great because this was a most important thing to do after the crisis. But, the not-so-good news is that, as the report finds, many banks do not yet have the financial muscle to provide enough credit to vigorously support the economic recovery. And, what it means is that after having gone through the stage of stabilizing the banking system and then repairing balance sheets, banks now face a new challenge, and that is of adapting the business models to the post-crisis economic and market realities, and also to the new regulatory environment. We have looked at a sample of the 300 largest banks in advanced economies in the report. These banks comprise the bulk of the banking system in advanced economies. What we find is that 40 percent of the banking system in advanced economies, measured by assets, 40 percent is not strong enough to adequately support credit in helping support the recovery. They cannot supply adequate credit in support of the recovery. In the euro area, this proportion increases to about 70 percent. These banks will need a more fundamental overhaul of their business models, including a combination of repricing existing business lines, of reallocating capital internally across activities, of retrenching in some activities, even consolidation: mergers and acquisitions. We think that in Europe the comprehensive assessment that is being carried out by the European Central Bank and which is about to finish provides a strong starting point for this much-needed change in bank business models which banks have to do themselves. I would like to give you an example. I said banks are safer now. They're safe, but they're not strong enough to vigorously support the recovery by providing credit. This is like if you go to the doctor for a medical checkup and you get a clean bill of health, and the doctor tells you, "Now you're capable of going back and leading a normal life." And you say, "That is fine. But, you know what, I'm an athlete and I need to do more than lead a normal life. I need to run." So you're a bank which is safe, but you need to run in support of the economic recovery. That is the extra bit which is needed after you have ensured safety: the transformation of business models over time. Let me go now to shadow banks. Here again we have good news and some concerns. The good news is that capital markets are now in a position to provide more financing to the economy, and that is a very welcome development. But, at the same time, what we are seeing is that there is a shift of the locus of risks to the shadow banks and that is the not-so-good news. Credit-focused mutual funds, mutual funds which invest in fixed income assets, have seen massive asset inflows and have collectively become one of the largest holders of U.S. corporate bonds and foreign bonds. The problem is that these massive fund inflows have created an illusion of liquidity in fixed income markets. What I mean by that is a situation where the liquidity promised to investors in good times is likely to exceed significantly the liquidity which is available and provided by markets at times of stress, especially as banks have now less capacity to do market-making activities. So, people think they have much more liquid assets than they really have when the market turns around. This is certainly an issue, this liquidity illusion. At the same time, a very important development in recent years is that emerging markets have become a very important destination for portfolio inflows from advanced economies. For example, advanced economy investors currently allocate more than 4 trillion dollars in portfolio investments to emerging market asset equities and bonds. And that is about 13 percent of their total investments, a share which has doubled over the past decade. What this means is that there are now much more closer financial interlinkages between advanced economies and emerging markets and therefore that shocks emanating from advanced economies have the potential to propagate more quickly to emerging markets. Together, the two factors that I have just described, the liquidity illusion in markets and this greater interconnectedness between advanced economies and emerging markets, are factors which will amplify the impact of shocks on asset prices. And if shocks are adverse, this will lead to sharper price falls and more market stress. Such an adverse scenario is something that would take a toll on the economy by hurting wealth and demand, but also at the limit could even compromise global financial stability. This chain reaction could be triggered by a variety of shocks, but let me mention the two that I think are most significant. One is geopolitical flare-ups, and the second is a bumpy normalization of U.S. monetary policy. So, these are the risks surrounding the global financial system, but the question is what should the authorities do in order to preserve the things that go well and then to address the challenges which are still pending in the case of banks and in the case of nonbanks? What should the authorities do to safeguard financial stability while at the same time strengthening the recovery? For this, and I come back to the main initial theme, policymakers need to address this new global imbalance between too limited economic risk taking and financial excesses. They should use various policies. Let me say that regarding monetary policy, accommodative monetary policies remain essential in those places where demand stays weak, while in those places where demand is recovering, then over time it would be natural to normalize monetary policies as is expected to happen in the United States and maybe also in other advanced economies, but not in others. But monetary policy cannot accomplish everything. Monetary policy cannot be the only game in town. It needs to be supported by other policies, by structural policies, like those discussed yesterday at the WEO, by smart fiscal policies, which will be discussed in detail in the Fiscal Monitor later today, but also by financial policies which is the main focus of the Global Financial Stability Report. Each of these policies needs to play its role. What should financial policies do? Financial policies can help rebalance both the economic risk taking and the financial risk taking. Regarding economic risk taking, financial policies must support an improved flow of bank credit to the economy. As I mentioned before, in order to do so banks need to do their homework in adapting their business models, but supervisors and other authorities can facilitate and support this structural transformation which would allow banks to enhance their profitability without taking excessive risks and provide more credit to support the recovery. This is something which is particularly important in Europe, where banks play a major role in financing the economy. Financial policy can also play a decisive role in addressing financial excesses through micro prudential and macroprudential policies. For example, in the asset management sector, which has been so much in the newspapers lately. Greater oversight is needed to ensure that the redemption terms are better aligned with the underlying liquidity conditions of the assets. Basically, reduce the liquidity illusion in markets. Also, more comprehensive monitoring and reporting of leverage in the non-bank sectors and also in the corporate sector in emerging markets would be essential to help identify areas of potential vulnerabilities. And to safeguard against global liquidity strains, bilateral and multilateral swap lines could be deepened to mitigate excessive volatility. All of these policies will strengthen the financial system by leading to more resilient financial institutions, and also by helping contain procyclical asset price and credit dynamics, something which is highly relevant given the market and liquidity risks which are accumulating in the shadow banking. Let me conclude by emphasizing that policymakers, in advanced economies and emerging markets, need to be alert to these growing challenges to financial stability, and take further actions now, both to promote economic risk taking in support of growth, and to address excesses in financial risk taking to safeguard global financial stability. Thank you. Ms. Stankova: We will take your questions. Please give your name and your affiliation when asking your question. QUESTION: About the banks, there seems to be some paradoxes in what the banks should do to support the recovery. They should take more risks to increase their profitability and they should reprice. This could also lead to the now safer banks taking on more risks and to credit becoming more expensive which could hurt the recovery. I was wondering, what is your view on these paradoxes? Mr. Viñals: I think that banks need to have sufficient muscle to provide credit and that depends on two things. It depends on how large are the capital buffers that they have in order to re-risk their balance sheets, and at the same time on how profitable are the activities in which they're going to be engaging. So, what we suggest is that banks need to do a number of things. They, in a number of cases, need to move away from activities which may be appropriate now and may even be profitable now in the context of very cheap funding that they obtain from the European Central Bank or from other central banks, the Fed, the Bank of Japan, and in some cases this is going into very low profit-making activities or even into the purchase of government bonds. Because that is something which is safe and doesn't require any risk weight, so that doesn't consume regulatory capital. But, what we would like is for banks to be able to reallocate capital to other activities, and it may be that, as credit demand recovers in the context of an economic pickup, banks need to provide more credit at somewhat higher interest rates. But that is something which would be fine in the context of an economic recovery. If banks don't provide the credit which is demanded, then you would have a problem. So that paradox would be lessened. But, that is not all. Banks in addition to that need to find new, reasonable ways of improving their earnings capacity on a sustainable level. They need, for example, as some banks are already doing, to engage in partnerships with nonbanks, where both banks and nonbanks use their comparative advantage in joint ventures. There are a number of cases where banks need to think seriously about consolidating through mergers and acquisitions because maybe there are too many banks in certain parts of the world for the business which is available. That would lead to a more useful industry to basically having synergies, having more efficient banks, and banks that have the ability to thrive and provide more credit. There would be instances where the best situation, the best solution would be for banks to exit. In those cases where banks are not viable, banks which really don't have a future, because they can be kept alive, but basically little else, maybe this is a situation where exit should be facilitated so that the only players which are left are those which are vibrant and strong enough to support the economy. There are a number of things that banks can do and the authorities can certainly facilitate this process. QUESTION: You mention in the report the risks of asset management companies investing a lot of money in emerging market bonds and high yield and corporate bonds. Would you include eurozone government bonds? There has been a lot of investment in Italian bonds and Spanish bonds by large asset management companies. And, could you also be a little bit more specific in terms of what you would recommend regulators suggest asset management companies do in terms of preparing for this type of situation that you foresee? You mention redemptions, but could you perhaps be more specific in terms of what regulators should say asset managers should do? Mr. Dattels: Regarding what we highlight as a potential risk is the concentration of holdings of asset managers. What we flag in the report is that funds need to be aware of the portion that they are holding of particular issuers. So we shine the light a little bit on the corporate sector, where a number of large funds hold in excess of 20 percent of an individual issuer. The point being there, if there is pressure on the fund, this may have knock-on effects to the issuer and effectively a dislocation of prices unrelated to general market conditions or the credit conditions of the issuer. And that is why we flag in that context emerging markets, but also advanced economy corporates. The message there is that the funds need to think a little bit about not only a portfolio management view, but also a systemic view. In other words, the fact that they're sizable means that their actions have wider implications. In the context of the euro area sovereign bonds, those markets are reasonably broad so that this concentration risk is not there. What we do highlight in the report is the pricing of those bonds, according to our models, looks somewhat stretched against the underlining fundamentals that would determine the spreads. So again that sort of fits into our broader notion of some stretched valuations, and that segment, high-yield eurozone peripheral bonds and emerging markets have been areas where investors have reached for yields. Mr. Viñals: There was a second part of the question, which has to do with what we should recommend that regulators do for the asset management industry, mutual funds, so on. I think that one important thing is to raise awareness of what may be the underlying risks, particularly the market liquidity risks I have mentioned, so that investors are well informed. That is something that the industry should do in terms of clearly communicating to the investors, also, what is the underlying liquidity of the assets that they're investing. I think it is important also that regulators stress test liquidity conditions in mutual funds in order to see what is the extent of liquidity risks there. It is also very important that there are adequate liquidity standards, minimum liquidity standards, so that these vehicles can cope with redemptions. And I think it is also very important to tighten the definition of what is really a liquid asset, so that there are no false perceptions of something which is declared to be liquid for regulatory purposes, but is not really liquid in reality. So, overall, raise awareness and strengthen oversight of those parts of the shadow banking system and including asset management and mutual fund industry which may pose the type of risks that I have referred to. QUESTION: Italy's banks, which took money from the ECB two weeks ago, say that they fail to lend money to firms, so the firms don't have money to invest. Do you think the No. 1 problem is that banks are not strong enough? They do not have enough muscle? Is this the No. 1 problem? Ms. Maechler: We think that Italian banks have done a lot, have really strengthened the balance sheet and we're looking forward to the results of the comprehensive assessments from the ECB. It is clear they're facing a lot of cyclical headwinds from low demand, as you mention. Another one is, of course, also the very high outstanding stock of NPLs. In the euro area as a whole, 800 billion of NPLs outstanding that needs to be absorbed. That is clearly a challenge they have to go through. Now, our analysis suggests that beyond these cyclical headwinds, even if you account for these cyclical headwinds, the banks in the euro area have to shift to new business models in order to be ready to meet the demand when the economy recovers. Because, at this time we find that a significant share of the banks, in fact in the euro area it is over 70 percent of the banks, are not strong enough to deliver credit growth that is greater than 5 percent on an annual basis. Clearly they need to shift to a new business model. They need to reprice some activities. They need to shift capital across different activities. They may need to restructure. As Mr. Viñals said, they may have to consolidate in different ways in order to make sufficient profits to meet the demand on a sustainable basis of credit. QUESTION: I think it is fair to say that in 2006 nobody saw the financial crisis stemming from the U.S. subprime mortgage market. So when you look around the world, what is the next subprime going to be, do you think? Mr. Viñals: Well, we don't engage in that type of exercise, because we don't have a crystal ball. I think that our job is, rather, to point out where we see risks emerging, which could over time become systemic, so that the authorities take measures in advance so that we do not have another financial crisis. And, the focus that we're putting in this report in terms of financial risks is on the shadow banking system. We have devoted a whole chapter, Chapter 2 of the Global Financial Stability Report, to analyze the shadow banking system. And that shadow banking system is becoming very important in some parts of the world. In the United States, it is at least as systemic as the banking system. And we call for special attention to be paid to shadow banking, and for the incipient risk there in terms of market and liquidity risks to be adequately controlled so that they do not create problems later on which may be too big or too complicated to handle. So, this is our job. Ms. Stankova - A question on line to follow up on the question of the shadow banking. Can you elaborate on the risks of shadow banking in Latin America, particularly for the Caribbean region and the Dominican Republic? Mr. Dattels: What we observe in the Latin American region in general is a shift from bank-sourced financing to international capital markets, so we have observed the corporate sector take advantage of the rather benign and low-interest-rate environment to tap international markets. And that growth in corporate issuance, some of this has been used to stabilize the liability structure, so there has been some terming out. That has helped strengthen the corporate balance sheets. But, also, to a degree it has increased the leverage levels in Latin America in general. The concern that we have pointed out to in the last report, in April, and we follow-up to an extent in this report, is the impact of this increased leverage against the broad slowdown in the economy. These economies are weakening. The commodity prices have declined. So they're faced with an external shock, if you like, from the slowing global growth. And that is impacting their earnings. So, what we flag is because the earnings, the corporate earnings are rather weak, even though interest rates are low, the relationship between the earnings on the one hand, and the interest service on that debt is weakening, it is weakening to the point that over the broad scope of corporates, almost 25 percent of the corporate debt is what we would classify as debt at risk. And, debt at risk, by our definition, is where earnings are covering interest expense only at two times or less. So we have that. Mr. Viñals: Let me add one thing, which I forgot before, but it is very relevant to the question on shadow banking. One should not get the idea that nothing is done on the regulatory front to address the risks in the shadow banking. In fact, there are a number of initiatives which are being put together at the global level under the Financial Stability Board, and which are quite advanced, but these regulations need to be finalized, and these regulations need to be implemented, but that is something which is in the pipeline. So, I think that regulators are already doing work which goes in the direction of tackling some of the risks that we are outlining, and it is important that these things are put in place soon, because the risks are growing quite rapidly as well. Ms. Stankova: One more question on line to perhaps follow-up also some questions, this combined question that we already answered. This is a question from Turkey. The global banking system insists on postponing the Basel reforms, what should be done to contain risks regarding shadow banking? Also, can you elaborate on risks regarding Russia? Are you expecting any kind of massive outflows from emerging markets such as Turkey, Brazil, and others? Mr. Viñals: Let me say a couple of things. In terms of Russia, I think what we have seen so far is that the geopolitical uncertainties surrounding the Ukraine - Russia issue have remained quite localized, and have affected only some of the countries which are most closely linked to these two economies. So, unless there is a very substantial escalation that can lead to real global concerns, and which may trigger something like a significant increase in global risk aversion, and let's hope that things are put in place so that doesn't happen, if things remain the way they are I don't think this is something which would lead to massive outflows from emerging markets. But, if you have an exacerbation of geopolitical risks, yes, this is one of the shocks that we think could lead to an unravelling of present market conditions and which could be quite damaging. Regarding the Basel norms, Basel III is finalized in most aspects, has been finalized and there is now a process of implementation in a number of advanced economies and emerging markets, so implementation is going forward. So I don't think that this is something which is not happening or which is being excessively delayed. Implementation is happening. Although it is true that there are a couple of things on the net stable funding ratio and the leverage ratio there are a couple of decisions which are important that need to be made, all the other parts of the Basle III package have been finalized and have been implemented. QUESTION: So in your remarks you mention, you cite two examples, geopolitical risk and exit strategy of the Federal Reserve, may be the trigger of a serious chain reaction. I wonder if you can elaborate more on that, and what kind of incidents might also be the trigger and then we will see a series of chain reactions? How serious it might be on the global economy if it happens? Mr. Viñals: Taking into account that we start from a situation where although there are no financial assets which are way out of line with fundamentals, there are many assets which are somewhat richly valued relative to fundamentals. And, we start from a situation where volatility is very, very low. All of this has the potential for decompressing, if there are important adverse shocks. I've mentioned two types of shocks, geopolitical shocks, and a bumpy U.S. exit from easy monetary policy. Now in terms of geopolitical shocks, something which is interesting is that outside of the specifically affected regions in terms of geopolitical issues, Russia, Ukraine I mentioned and some in the Middle East, markets at the global level, market sentiment has been quite resilient so far. But one cannot count on that being always the case if somehow these geopolitical issues were to take a much higher profile. That is certainly a risk. In terms of the exit from the United States's very low interest rates at present, zero policy interest rates, near zero interest rates, the fundamental thing is how is the process going to be conducted on the part of the Fed, in terms of the timing of the process, and in terms of the communication of the process. And, I think that it is very important that the Fed is very aware that they have to conduct the process in a gradual manner consistent with the state of the economy, with the developments in the price domain, in the employment domain, but being mindful of the repercussions for the rest world. The question there is whether, at the end, the exit from monetary policy would be a smooth process, and this is our baseline, or would be bumpy. And that is the adverse scenario. So let's hope that both on the part of the Fed and on the part of markets, we end up with a smooth scenario. But, we could end up in an adverse, bumpy scenario, and because we don't know what the future is going to be like, that is why it is important that policymakers already prepare and try to prevent the potential complications that could arise from a less orderly unraveling of the present financial market excesses. QUESTION: (In Spanish; no interpretation provided). Mr. Viñals: Yes, the liquidity illusion is a very important issue that we have flagged. Regarding banks, before the crisis banks did many things which they should not have done, and even recent discoveries have told us that some inappropriate practices have continued up to recently and that is something which should not have happened, and that should be discontinued right away. As we keep emphasizing in the report, banks need to think that the present situation of very easy financial conditions, monetary conditions, in terms of the funding they get, will not be there in the future, and they need to adapt to this new reality. So, that is more of an issue in advanced economies than emerging markets, but let's not forget that a key role of banks in a market-oriented economy is to support economic growth by providing sufficient financing for the real economy. And, you're right, perhaps before the crisis there were too many resources devoted by banks to financing activities which were inappropriate, which were not reasonable, which were growing too fast, which were not prudent, and also banks engageg in a lot of practices with vehicles which at the end of the day did not serve the purpose of the real economy. And that is a focus of the report. Banks should be strong, and they should refocus the business models so as to provide more lending to the economy because that is needed. QUESTION: You talk about the necessary changes in the business model of banks in Europe, especially, but what you expect to be the trigger of those changes? Do you expect the banks to do that spontaneously? Would you say that there is a need for some regulatory reforms? As you know there is now a European law in the pipeline about the changes needed in the structures of banks. Is that the right fix for this business model issue? And second, you talked about consolidation, but you didn't say a word about too big to fail, too complex to resolve issue. Is that not a problem anymore? Are very large banks still a problem for financial stability or not? Mr. Viñals: Let me tackle at least part of the question, and then my colleague on the right may complement what I would say. I think that in Europe things go in stages. I think it is very important that the comprehensive assessment is finalized. That is something which is going to happen -- the purpose of it is to bring transparency and to enhance confidence in European banks. And, we're looking forward to the publication of the results later in the month, to be done in a way that achieves this end. The fact that you are going to have a single supervisor at the European level for banks, with strong powers, without national biases, the fact that you are going to have a framework like the bank recovery and resolution directive, like the single resolution mechanism, like the single resolution fund, all of this is a framework that was not there before, and which is there in order to help resolve banks. And, I am confident that with a better, higher-quality supervisory framework at the European level, and with a strong framework for resolution, this is something which is going to be very helpful for banks to move forward in all of the dimensions that we're talking about in the report. Now, regarding the too-big-to-fail issue, the question is, how much has been done and what remains to be done. I think that this is an issue which is not yet settled, I prefer to talk about too important to fail rather too big to fail because it is not size that matters, it is size and many other things, such as complexity, interconnectedness, etcetera. But there have been important steps taken by agreeing on systemic capital surcharges on systemically important banks at the global level. And, now there is a process also to do that with domestically systemically important banks. There is a supervisory framework which is being put in place in order to exercise more intense supervisory scrutiny on systemically important banks, but there are issues that still need further advancement. For example, the so-called living wills, the recovery and resolution plans for individual institution, they need to be finalized and implemented. You also need to make more progress on the issue of resolution, national frameworks, which can achieve more effective and efficient resolution. Cooperation to deal with cross-border resolution, what happens when you have banks which operate in different countries and they need to be resolved, and ensuring that systemically important banks at the global level have sufficient loss absorption capacity in the case of resolution, all of this is part of the regulatory initiatives which are being developed but which yet have to be implemented. So, progress is being made, but the regulatory reform agenda has not yet been completed. Mr. Jones: Regarding your question about whether banks will do this voluntarily, in some sense they will because equity markets will reward banks that are able to make changes in their business models and generate sustainable levels of capital on an ongoing basis. Regulators also have a role to play in terms of facilitating mergers and acquisitions of weaker banks across borders. They also can encourage banks to avoid cross subsidizing different business lines and to ensure that banks business models are aligned appropriately to the risks they are taking. They can also ensure that the weak tail of banks has been in a sense artificially suppressing the returns in the banking system, are cleaned up, and that may involve some banks exiting altogether. So there are a number of steps that regulators can take to encourage that process and to facilitate that process. And also financial markets will encourage that through the natural rewards of making capital raising easier for banks that have better business models and more viable business models. So, both financial markets and the supervisors have a role to play in ensuring that this happens in a smooth process. Ms. Stankova: Let me take another question from online, which is: What is your assessment of the state of the shadow banking in China? Mr. Jones: On China, I think the ongoing challenge is really to find the right mix of policies to reduce the debt related vulnerabilities while maintaining adequate growth. I think in terms of the shadow banking system, the authorities have taken a number of measures to make progress to reduce the risks in the shadow banking system such as the tighter regulation of trusts that has happened in wealth management products and some of the restrictions on interbank activity. But, the growth of non-bank lending has decelerated as a result, so that is a positive development, and growth remains strong. So some vulnerabilities continue to be accumulated. The policy recommendations that we have in the report are both for the authorities to continue to monitor and contain the rapid growth in leverage in the corporate sector, and also particularly in the real estate and construction sectors where declining profitability and cash flows have become an issue. But more broadly, to help rebalance credit allocation toward more productive areas in the economy, and this requires a more efficient risk pricing in the financial system, a gradual rolling back of the implicit guarantees, and a gradual increase in the default of nonviable firms. So building on these current policy efforts that they have already taken, we see further steps that would be helpful to introduce into the financial system and ensure proper regulation of the shadow banking system. Ms. Stankova: Thank you. With this we conclude the press conference. TOCQUEVILLE GOLD STRATEGY INVESTOR LETTER / TOCQUEVILLE | Etiquetas: Gold Tocqueville Gold Strategy Investor Letter Third Quarter 2014 Portfolio Manager and Senior Managing Director Through September 30, the $US gold price declined 6%, after giving up much of the stronger gains that had been achieved through most of the year. The recent bout of weakness began in late August and coincided with the breakdown of the Yen and the Euro vs. the US dollar. Commentary from all quarters is aggressively negative. Technical analysts are virtually unanimous in their bearishness. On a near term basis, this looks and feels like a bottom to us. On a longer term view, we are more bullish than ever. Notwithstanding near term weakness in the gold price, most of our key holdings in the gold mining sector have managed decent gains, compared to a 2.78% decline for our XAU benchmark. We attribute our positive performance to our selection of well managed companies which are able to create value independently of gold price action. Value creation can come about in many ways, including accretive merger and acquisition activity, progress in the construction of new mines, or successful exploration. We continue to believe that investing in the securities of well managed gold mining companies offers the most dynamic and reliable exposure to the upside potential in the gold price. Our research activity and portfolio selection is based on emphasizing the value creators in the sector and avoiding the value destroyers. The long term fundamentals for gold are stronger than ever, in our opinion. Overt currency debasement is the chosen path in Europe and Japan. The race to the bottom in these currency wars is not limited to our trading partners. In a recent article, Kenneth Austin, former chief economist for the Obama administration, calls for an end to US Dollar reserve status, seeing it as a drag on domestic growth. The use of the Chinese Renminbi to settle trades away from the dollar has grown dramatically in recent years. In the first half of 2014, the Bank of China cleared RMB payments equivalent to an impressive $18.3 trillion, double the previous year. The formation of institutions such as the new BRICs Bank and the Shanghai Gold Exchange enable participants to circumvent the $US and US financial institutions in the conduct of trade. The Chinese Central Bank has opened 1200 non-Chinese interbank clearing accounts to settle trades in Renminbi. In September, Britain announced plans to issue a Renminbi denominated bond. These are perfectly logical developments given the size of the Chinese economy and do not in and of themselves foreshadow a decline in the dollar. However, the advance of the Renminbi as a reserve currency does raise the question as to what central banks will do with a potentially huge surplus of dollars. The US dollar strength that has been credited for the weakness in gold is in our opinion both an illusion and a misconception. The "strength" reflects only weakness of alternate reserve currencies and flight of speculative capital. We believe the condition to be of limited duration both long and short term. CFTC speculative trader dollar longs stand at a 15 year high, an extreme that typically marks an inflection point. The misconception is the notion that the dollar and gold trade inversely. The correlation coefficient between the dollar index and $US gold is only a weak .3389 since 12/31/03. The chart below demonstrates that the relationship between the gold price and the dollar index is quite tenuous. The "strong" dollar, should it persist, will represent a dilemma for policy makers and politicians in the form of undesired deflationary pressures spanning the globe. For example, the weak yen threatens Chinese economic strength. Should that result in a round of currency debasement throughout Southeast Asia, the effect would be analogous to global monetary tightening via exchange rates, as suggested in a September note by Albert Edwards of SocGen. Since the financial crisis of 2008, global leverage is greater than ever, both relative to GDP and in absolute terms. Global debt has increased 40% since 2008 versus a 22% increase in global GDP. The increased debt burden is manageable only because interest rates are at record lows. A rise in interest rates would in our opinion cause severe damage to financial assets, whose valuations have been inflated by money creation and zero rate of interest for risk free assets. Financial assets are valued based on discounted cash flows. In the ultra-low interest rate environment, what are the chances that the discount rate will decline from here? We suspect this could happen only if a collapse of expected earnings was foreseen. The prospect of higher rates would also create havoc, in our opinion, for credit quality. We believe that three things must happen to not upset the very unstable applecart in which financial asset values reside: 1) the pace of global growth must increase meaningfully; 2) debt issuance must stabilize; 3) inflation must remain tame. We also believe that the odds of achieving this trifecta are non-existent. The just published 16th report on the global economy by The International Centre for Monetary and Banking Studies warns of "a poisonous combination of high and rising global debt and slowing nominal GDP….Contrary to widely held beliefs, the world has not yet begun to de-lever and the global debt to GDP ratio is still growing and breaking to new highs (160% in 2001; 200% in 2009; and 215% in 2013)." Strong equity markets have been the major headwind for gold over the past three years, in our view. Who needs financial insurance when the weather is clear? Zero interest rates fostered by central bankers have forced money into risky and illiquid assets stretching valuations of lower quality categories to near record levels. Three years of positive returns have resulted in investor complacency. Lofty financial asset valuations are not the only issue. What if fundamentals, economic growth and rising corporate earnings, begin to deteriorate? What if the Fed, intent on staying the course, begins to tighten into economic weakness? There are numerous examples of spreading economic weakness in the U.S. including recent soft data for housing, retail, and durable goods. Europe, already struggling, is facing increased headwinds from economic sanctions on Russia. The gold/silver ratio has broken above a multiyear top of 68 and now stands at 71.3. As with credit spreads, this ratio is often a reliable signal of impending economic contraction. The behavior of this indicator is consistent with the persistent weakness of commodity prices. Credit spreads have begun to widen as well. Expanding earnings and valuations, the underpinnings of the four year bull market in financial assets, may be approaching an inflection point. A reversal of this cycle would in our opinion restore interest in gold. Sentiment indicators are at rock bottom levels. The Ned Davis Gold sentiment index has dropped to "0", a level approached only once in the past eight years. Over the past 20 years, readings below 35 have reliably been followed by rallies. The Hulbert Gold Newsletter Sentiment Index currently stands at 46.9%, the second lowest reading in 30 years. These are cheery numbers to a contrarian, reminiscent of the low regard held for gold in the late 1990's. There is more than bleak sentiment going for gold. In our opinion, a gold supply crunch is around the corner. Headlines and front page stories on this are yet to come. Gold mining capital expenditures and exploration spending are in a virtual freeze mode. There have been almost no discoveries of large new gold ore bodies in the past 8 years. Ore grades are steadily declining and the world has become less hospitable in general to hard rock mining. We agree with Goldcorp CEO Chuck Jeannes' prediction of peak gold production this year or next, to be followed by a multi-year decline. In our opinion, many producers are liquidating capital and reserves to tread water financially. We believe this will ultimately lead to a frenzy of takeovers, targeting both explorers and developers, the back bone of our portfolio. The Osisko takeover battle earlier this year exemplifies what we believe lies ahead. Another noteworthy development is the accelerated flow of gold bars from vaults in Western financial capitals to Asia and especially China. The magnitude of this shift can only be approximated and probably understated by official import statistics. A recent note by Na Liu of CnC China offers convincing arguments that 2013 Chinese demand was twice the 1000 tonnes reported by the World Gold Council and the China Gold Association, based on withdrawals from the Shanghai Gold Exchange. It must be noted, according to Mr. Liu, that none of the withdrawals from the SGE are accounted for by official sector demand. The puzzle of robust demand for physical gold accompanied by a declining gold price can in our opinion be understood only as a massive destocking by Western investors resulting in the transfer of bars from vaults in Western financial capitals to their counterparts in Asia. If Chinese consumption has been seriously underestimated as suggested here, the physical market is much tighter than conventionally believed. Therefore, only a modest reawakening of interest by Western investors could have an outsized impact to the upside. The launch of the Shanghai Gold Exchange on September 18th is, in our opinion, emblematic of China's intent to become a major force in the bullion market. In an editorial published July 30, 2014, Song Xin, President of the China Gold Association and Party secretary, stated that China should accumulate 8500 tonnes in official gold reserves, and that accumulation of the metal for official and private use was a matter of national interest. For reference, 8500 tonnes would require more than three years of global mine supply. Song's predecessor had previously published an article in Quishi magazine (2012), the main academic journal of the Chinese Communist Party's central committee which included the following passage: The state will need to elevate gold to an equal strategic resource as oil. Currently, there are more and more people recognizing that "gold is useless" story contains too many lies. Gold now suffers from a "smokescreen" designed by the US, which stores 74% of official gold reserves, to put down other currencies and maintain the US Dollar hegemony. Going to the source, the rise of the US dollar and British pound and later the euro currency, from a single country currency to a global or regional currency was supported by their huge gold reserves. Individual investment demand is an important component of China's gold reserve system, we should encourage individual investment demand for gold. Practice shows that gold possession by citizens is an effective supplement to national reserves and is very important to national financial security. This is a clear statement of China's objective to elevate the Renminbi to reserve currency status, employing in part a strong backing of physical gold, if achieved, will dislodge the US dollar as a dominant reserve currency and in our opinion cause a significant re-pricing of the metal in US dollar terms. We do not believe that this outcome is what the bullish US dollar camp has in mind. The aggressive divestiture of gold by Western investors has been of immense assistance to Chinese ambitions. As suggested by Alan Greenspan in the latest issue of Foreign Affairs, the accumulation of a sizable gold reserve is a low risk, high reward path for China to offset the risk that their $4 trillion in foreign exchange reserves will be debased by their respective issuers. We take comfort that our positive view of the future dollar gold price is shared by those who understand the difference between synthetic and physical metal, and who regard the real substance as a matter of strategic imperative, not as plaything for macro traders. We believe that China's negative assessment of the future prospects for the US dollar is correct and that our investment strategy of investing in the shares of value creating gold miners offers sensible and dynamic exposure to the inevitable re pricing of gold in US dollars. MR. ERDOGAN DANGEROUS GAME / THE NEW YORK TIMES EDITORIAL | Etiquetas: ISIS, Middle East, Recep Tayyip Erdogan, Turkey Mr. Erdogan's Dangerous Game Turkey's Refusal to Fight ISIS Hurts the Kurds By THE EDITORIAL BOARD Turkey's president, Recep Tayyip Erdogan, once aspired to lead the Muslim world. At this time of regional crisis, he has been anything but a leader. Turkish troops and tanks have been standing passively behind a chicken-wire border fence while a mile away in Syria, Islamic extremists are besieging the town of Kobani and its Kurdish population. This is an indictment of Mr. Erdogan and his cynical political calculations. By keeping his forces on the sidelines and refusing to help in other ways — like allowing Kurdish fighters to pass through Turkey — he seeks not only to weaken the Kurds, but also, in a test of will with President Obama, to force the United States to help him oust President Bashar al-Assad of Syria, whom he detests. It is also evidence of the confusion and internal tensions that affect Mr. Obama's work-in-progress strategy to degrade and defeat the Islamic State, the Sunni Muslim extremist group also called ISIS or ISIL. Kurdish fighters in Kobani have been struggling for weeks to repel the Islamic State. To help, the Americans stepped up airstrikes that began to push the ISIS fighters back, although gun battles and explosions continued on Wednesday. But all sides — the Americans, Mr. Erdogan and the Kurds — agree that ground forces are necessary to capitalize on the air power. No dice, says Mr. Erdogan, unless the United States provides more support to rebels trying to overthrow Mr. Assad and creates a no-fly zone to deter the Syrian Air Force as well as a buffer zone along the Turkish border to shelter thousands of Syrian refugees who have fled the fighting. No one can deny Mr. Assad's brutality in the civil war, but Mr. Obama has rightly resisted involvement in that war and has insisted that the focus should be on degrading ISIS, not going after the Syrian leader. The biggest risk in his decision to attack ISIS in Syria from the air is that it could put America on a slippery slope to a war that he has otherwise sought to avoid. Mr. Erdogan's behavior is hardly worthy of a NATO ally. He was so eager to oust Mr. Assad that he enabled ISIS and other militants by allowing fighters, weapons and revenues to flow through Turkey. If Mr. Erdogan refuses to defend Kobani and seriously join the fight against the Islamic State, he will further enable a savage terrorist group and ensure a poisonous long-term instability on his border. He has also complicated his standing at home. His hesitation in helping the Syrian Kurds has enraged Turkey's Kurdish minority, which staged protests against the Turkish government on Wednesday that reportedly led to the deaths of 21 people. Mr. Erdogan fears that defending Kobani would strengthen the Syrian Kurds, who have won de facto control of many border areas as they seek autonomy much like their Kurdish brethren in Iraq. But if Kobani falls, Kurdish fury will undoubtedly grow. The Americans have been trying hard to resolve differences with Mr. Erdogan in recent days, but these large gaps are deeply threatening to the 50-plus-nation coalition that the United States has assembled. One has to wonder why such a profound dispute was not worked out before Mr. Obama took action in Syria. PUTIN SEEKS SOLITUDE AMID RUSSIA´S PERFECT STORM / STRATFOR GLOBAL INTELLIGENCE | Etiquetas: Russia, Vladimir Putin Putin Seeks Solitude Amid Russia's Perfect Storm Russian President Vladimir Putin celebrated his 62nd birthday Tuesday in a peculiar fashion: by himself in the Siberian forests. For the past few days, Putin's spokesman, Dmitri Peskov, has brushed off journalists' questions about why the president decided not to celebrate his birthday in Moscow or do other work as he has in previous years. This is just another odd piece to an increasingly complex puzzle surrounding the stability and future of the Russian president and his government. Current Instabilities Russia is in the eye of the perfect storm. Though the crisis with Ukraine has been reduced to a simmer, Russia has seen a strategic reversal in its critical borderland. In addition, the crisis moved the West to enact sanctions on Russia and loosen many financial and economic ties to the country. Now the Kremlin is in the midst of an economic crisis that is every bit as serious as the Ukraine situation. In the past two days, Russia's central bank used $1.6 billion of its currency reserves to shore up the Russian ruble. Since the start of 2014, the central bank has injected $51 billion in currency reserves to keep the currency stable. The Russian economy is projecting flat growth for 2014, while foreign investment into Russia has fallen by 50 percent. The Kremlin may have $630 billion in its reserves, but these funds are being used quickly in an attempt to fill the cracks. Concerns over Russia's financial stability have erupted into public battles between the various Kremlin factions. On Tuesday, Russian Finance Minister Anton Siluanov, a key figure in the liberal economic clans, publicly called on Putin to cut Russia's ambitious defense spending program. Russia is set to start a 10-year, $770 billion defense rearmament program in 2015. Siluanov reportedly rejected the plan during recent budget drafts in September, prompting Putin to move decision-making on defense spending under his office and away from the Cabinet. While Siluanov's argument against defense spending is financial, Putin also has to consider the security and political ramifications of such a decision. Russia's continued struggles in its borderlands will require a robust military. Moreover, Putin is using the defense budget to appease Russia's various security and defense circles. The Rise and Fall of Russian Leaders Though Putin has ruled Russia for 15 years in a centralized and autocratic fashion, like any other leader he must balance various factions within the country. His ability to manipulate the various political clans is what brought him to power. The lack of that ability is what caused the downfall of Boris Yeltsin in the 1990s, and many leaders before him. Yeltsin was unable to manage the competition between his own loyalists, the more liberal circles of economists and the security and defense circles. Yeltsin wildly shifted policies in order to retain a grip on power, such as his economic shock policies and the restructuring of the Federal Security Services. Such erratic moves contributed to the Russian economic crash, the breakdown of the security services and the erosion of Russia's military as it fought a savage war in the North Caucasus. Yeltsin's stumbling enabled Putin's rise to power. Putin understood that a Russian leader could rule only as long as he could balance the competing groups. Putin is a former KGB agent, tying him into the security circles, while his knowledge of Russia's need for Western technologies gives him an understanding of the more liberal economists. In his first years in power, Putin divided Russia's assets and tools of power between the clans, keeping them in constant competition and positioning himself as the ultimate arbitrator. The problem now is that the clan system has begun to crumble. The security circles are being blamed for failures in Ukraine, while the liberal economic circles are being blamed for the sour economy. Many personalities and groups are putting their own positions (and financial revenues) before the betterment of the state. Putin continues to try to maintain balance, as seen in the recent weeks of budget debates between the liberals and security circles. But Putin's 15 years of success at balancing the clans came during times of rebuilding and resurging for Russia. Now, Putin is attempting to find balance from a position of weakness. Putin's grasp on power is not easy to gauge from outside the Kremlin. The decision for new leadership is made within the Kremlin walls, not among the people. Previous Russian leaders, from Nikita Khrushchev to Leonid Brezhnev to Yeltsin, were removed or pushed aside by the ones closest to them. Thus, it seems fitting that the current Russian leader chose to celebrate his birthday far from the Kremlin and its clans. TRANSCRIPT OF A PRESS BRIEFING ON THE GLOBAL FINAN... TOCQUEVILLE GOLD STRATEGY INVESTOR LETTER / TOCQUE... MR. ERDOGAN DANGEROUS GAME / THE NEW YORK TIMES ED... PUTIN SEEKS SOLITUDE AMID RUSSIA´S PERFECT STORM /...
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Integrated Strategies for Home Visitors: October 2019 | BCCF Shop - Your Family. A comprehensive manual full of tools and ideas. Lunch will be provided throughout the training as well as coffee/tea and some healthy snacks at coffee breaks. Certificates provided upon completion and attendance of all five days. Certificates are not provided for partial attendance. Orah Chaye has been working with children and families for over 30 years. She has focused her community service delivery work with indigenous peoples, immigrants and refugees in a wide variety of contexts. She has extensively instructed ECE, and offered many professional development trainings. Orah coordinated the Vancouver Early Years Refugee Program, started the "Welcome to Canada" Children's Program, and coordinated the "Pop-Up Family Program" for refugees in temporary housing. She is committed to promoting social justice and building capacity and opportunities for professionals working with marginalized populations. Earlybird registration is $700/person. The price will rise to $800/person on August 6th.
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Most enterprises are adopting Kubernetes as a result of the endless benefits it offers. It is adopted for seamless container management; it provides high scalability and enhances communication / messaging. It can also allow for the addition of many lifetime applications when building a microservice. This means enterprises can make lots of changes as the project expands with little effort There is a high volume of traffic flow of messages in microservice architecture that is orchestrated by Kubernetes. Managing heavy traffic can pose major challenges, so enterprises have to give a lot of thought on how to effectively manage the heavy traffic in the system before deploying in Kubernetes. This implies that the operational and architecture requirements that are needed to support the production environment have gained significant focus. In a new microservice, each data model is disengaged from the rest of the system. But a project can grow bigger into thousands of microservices, which means the messaging traffic would grow into millions of messages every day. Therefore to achieve an effective messaging system between microservices, a robust communication mechanism must be adopted. Some enterprises attempt to solve this communication gap in Kubernetes using a Point-To-Pont connectivity system such as REST. However, REST can create restrictions and other complications in the messaging structure of the services. If there is no proper messaging solution, then there would be a need to carry out maintenance each time requirements are changed. Carrying out frequent maintenance is expensive, time-consuming, and unreliable. This problem cannot be solved by REST because of the many restrictions that come with it. To solve the problems in microservices architecture and Kubernetes, a messaging queue system must be deployed for effective management. A messaging queue system re-architects the stack and deploys a single focal point of communication for better communication. This ensures that each service communicates with the message queue broker in its own language. The message queue system would then deliver the messages to the services waiting for it. Building a well-managed messaging solution A messaging system cannot be effective if it is not native to Kubernetes. Enterprises must ensure that when building a message queue system, it is native to Kubernetes to leverage the advantages. The advantages are: Robust messaging queue system Secured system Low DevOps maintenance Well-connected ecosystem for logging in Kubernetes Message Queue advantages in Hybrid cloud solution Deploying enterprise solutions on a hybrid cloud service offers flexibility, agility, low cost, and total control. It also ensures that the enterprise can use on-premise and public cloud services concurrently. Flexibility to migrate from one solution to the other as cost and workload requirement changes is a big benefit. With a hybrid solution, enterprises can host their sensitive applications and workload on the private cloud solution while minor / less critical workloads and parts of the application would be hosted on the public cloud solution. Furthermore, with a private cloud service organizations pay for only the resources they use. These resources can be scaled up or down whenever needed. For hybrid clouds to run effectively, transparently, connect seamlessly, and interact, message queue must be deployed in Kubernetes. Message queues support a diversified messaging pattern; it ensures flexibility and can create a wide range of use cases. The most common use cases of the messaging queue in Kubernetes are Multi-stage Pipeline When messages need to be processed in a coordinated approach, a synchronous pattern would be implemented and used. The multi-stage pipeline approach allows for messages to be processed in a sequence between the different services. The multi-stage pipeline approach handles messages that cannot be processed as well. It does this by adopting a dead letter queue mechanism that accepts an unprocessed message and processes it in a predefined way. In a multi-stage Pipeline system, each service is considered a separate stage, and messages are passed between all the stages in the sequence. Message Stream When data needs to be streamed from many data sources such as big data and the Internet of things, it will adopt an A-synchronic pattern. This means big data are processed in a dedicated service such as pipeline, databases, storage, machine learning, and many other approaches. This is an effective mechanism that aggregates many producers to a smaller unit of consumers. With this approach, the delivery of the message is guaranteed. Pub/Sub Real-Time This is applied when a smaller number of producers need to send a message to a larger number of consumers. A service that behaves like a publisher would send a message to a channel. And the subscribers would receive the message in real-time via the channel. This acts typically like cable TV sending content its many subscribers around the world. Application Decoupling Connectivity solutions such as Application programing interfaces, databases, and storage devices would act as a router to send messages to the consumers. This means they connect with each other and distributes information's among them to send a unified data to the end-users A message queue system in microservices architecture can save time, money, as long as it is super easy to use. Native for Kubernetes message queue can seamlessly unify operation workflows and development, thereby saving great cost. Ease of use also ensures that the need for dedicated IT experts is not needed. A suitable message queue should ensure efficient memory usage, low latency, and include the fundamental messaging patterns (real-time pub/sub, request/reply, and queue) as well as supporting high volume messaging. Gradual Migration to Kubernetes Migration to Kubernetes must be done gradually to keep the data ongoing and ensure the business is operational. To achieve this Kubernetes messaging queue must connect seamlessly with the old and new system. Connectivity ensures that migration is carried out in a step by step procedure where new services are created without any downtime.
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07 3390 3177 | admin@pjsaccountants.com.au Tracy Barnett Lisa Haberfield Karen Sandes Nerida Davis Debbie Pendergast Superannuation (SMSF) Businesses Tax Information Individual Tax Information Tax Topics Explained What Small Business Qualifies for the CGT Rollover Relief? July 14, 2016 /in Tax /by Lisa Haberfield The Australian government has passed a law allowing small businesses to amend their legal structure without making them liable for capital gains tax (CGT). According to Small Business and Assistant Treasurer Kelly O'Dwyer, small businesses that discover that their current legal structure no longer suits them don't have to be stuck with it. With this legislation, they can restructure without incurring an instant CGT liability. The law is intended to be enforced beginning 1 July 2016, and affects: Handovers of depreciating assets, provided the balancing adjustment event as a result of the handover happens on or after 1 July. Handover of trading stock or revenue assets, provided the handover occurs subsequent to 1 July; and Handover of CGT assets, provided the CGT event from this handover is subsequent to the same date. This relief can be claimed should a small business hand over an active asset to another small business unit as part of a "real" business restructure without affecting the asset's economic ownership. Gains and losses resulting from the handover of active assets that are CGT assets, depreciating assets, trading stock or revenue assets between business organisations will be covered by the CGT rollover relief. To meet the requirements of the rollover relief, the handover of the asset or assets should be part of a "real" restructure of an existing business, versus "unethically tax-motivated strategies." The "genuineness" of the restructure will be determined using facts and situations. Some of the pertinent aspects are: Whether it is an authentic commercial plan executed to improve the efficiency of the business; Whether the re-assigned assets remain in the business; and Whether or not it is an initial move to, as the legislation words it, "facilitate the economic realisation of assets." All parties to the handover should do either of the following to be eligible for the rollover: A small business organisation with a turnover of $2 million or below for the income year when the transfer happens An organisation that has an affiliate that is a small business unit for that income year "linked" to an organisation that is a small business unit for that income year, or A partner in a partnership that is a small business unit for that income year If you need tax advice or guidance, contact PJS Accountants. We offer expertise in managing your tax affairs with a complete range of compliance, corporate and individual tax services. Our clients include large companies, SMEs, family businesses and individuals. Putting nothing to chance! Talk to one of our team members now! https://www.pjsaccountants.com.au/wp-content/uploads/2016/07/capital-gain-tax-feature-image.jpg 565 845 Lisa Haberfield http://www.pjsaccountants.com.au/wp-content/uploads/2015/09/pjslogo.png Lisa Haberfield2016-07-14 09:00:562016-12-02 13:31:24What Small Business Qualifies for the CGT Rollover Relief? DOWNLOAD OUR FREE EBOOK Sign up to receive our handy free eBook – From the Basement to the Boardroom – Practical Secrets for Starting a Home-Based Internet Business that Looks Like A Fortune 500 (and you'll also be subscribed to receive our monthly newsletter packed with up-to-date information on everything you need to know about tax and accounting for your business!) Accounting & Bookkeeping, Tax SMEs Set to Benefit from New Company Tax Relief The Australian government and crossbench senators have agreed… https://www.pjsaccountants.com.au/wp-content/uploads/2017/04/SMEs-Set-to-Benefit-from-New-Company-Tax-Relief-.jpg 400 700 Tracy Barnett http://www.pjsaccountants.com.au/wp-content/uploads/2015/09/pjslogo.png Tracy Barnett2017-04-10 09:00:212017-04-06 15:20:55SMEs Set to Benefit from New Company Tax Relief What You Need to Know About Car Salary Packages, FBT and After-Tax Running Costs One of the popular remuneration schemes for employees is including… https://www.pjsaccountants.com.au/wp-content/uploads/2017/02/What-You-Need-to-Know-About-Car-Salary-Packages-FBT-an-After-Tax-Running-Costs.jpg 400 700 Lisa Haberfield http://www.pjsaccountants.com.au/wp-content/uploads/2015/09/pjslogo.png Lisa Haberfield2017-03-06 09:00:462017-02-23 14:29:05What You Need to Know About Car Salary Packages, FBT and After-Tax Running Costs Asset Protection, Tax Key Legal Implications of Having a Company Car A car can be used as an incentive for employees. Employees can… https://www.pjsaccountants.com.au/wp-content/uploads/2017/02/Key-Legal-Implications-of-Having-a-Company-Car.jpg 400 700 Tracy Barnett http://www.pjsaccountants.com.au/wp-content/uploads/2015/09/pjslogo.png Tracy Barnett2017-03-02 09:00:422017-02-23 13:40:59Key Legal Implications of Having a Company Car Tips to Gain Small Business Customer Loyalty Many small businesses in Australia are still up to their neck… https://www.pjsaccountants.com.au/wp-content/uploads/2017/02/Tips-to-Gain-Small-Business-Customer-Loyalty-1.jpg 400 700 Lisa Haberfield http://www.pjsaccountants.com.au/wp-content/uploads/2015/09/pjslogo.png Lisa Haberfield2017-02-27 09:00:392017-02-23 13:46:23Tips to Gain Small Business Customer Loyalty Lessons to Learn from a Business Losing Money "Don't waste a good mistake, learn from it" - a piece of… https://www.pjsaccountants.com.au/wp-content/uploads/2017/02/Lessons-to-Learn-from-a-Business-Losing-Money.jpg 400 700 Tracy Barnett http://www.pjsaccountants.com.au/wp-content/uploads/2015/09/pjslogo.png Tracy Barnett2017-02-23 09:00:102017-02-20 16:24:48Lessons to Learn from a Business Losing Money Tegan Porter Small to Medium Enterprise The Redlands Individuals Tax Information PJS Accountants Level 1, "The Hub" 2 Loraine St Capalaba, QLD 4157 Australia Email: admin@pjsaccountants.com.au © Copyright PJS Accountants |Privacy Policy | Disclaimer | Site Map | Web Design by Online Specialists Tips to Write Off Bad Small Business Debts The Basics of Trust and Business Asset Protection
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Lea Thompson: Bio, Height, Weight, Age, Measurements Lea Thompson is an American actress. She is best known for her portrayal of Lorraine Baines in the Back to the Future trilogy and Caroline Duffy in the 1990s sitcom Caroline in the City. She has also played prominent roles in the films All the Right Moves, Red Dawn, Howard the Duck, Some Kind of Wonderful, and The Beverly Hillbillies. She portrayed Kathryn Kennish in the Freeform series Switched at Birth From 2011 to 2017. The youngest of five children, Thompson was born as Lea Katherine Thompson in Rochester, Minnesota, on May 31, 1961. Her parents are Barbara Anne and Clifford Elwin Thompson. Her siblings are Coleen, Barry, Shannon, and Andrew. She attended Marshall-University High School (Minneapolis). She danced professionally at the age of 14. She left professional ballet in favor of an acting career. Thompson's first role was as water skiing water show performer, she did not know how to water ski or even swim prior to being cast. She has been married to Howard Deutch since 1989. They have two daughters, Zoey and Madelyn. Lea Thompson Personal Details: Date Of Birth: 31 May 1961 Birth Place: Rochester, Minnesota, USA Birth Name: Lea Katherine Thompson Nickname: Lea Zodiac Sign: Gemini Occupation: Actress, Dancer, Director, Producer Race/Ethnicity: White (Irish, English, Scots-Irish, German, and distant Dutch) Eye Color: Light Brown Lea Thompson Body Statistics: Body Shape‎: ‎Hourglass Body Build/Type: Slim Body Measurements: 34-26-34 in (86-66-86 cm) Bust Size: 34 inches (86 cm) Waist Size: 26 inches (66 cm) Hips Size: 35 inches (89 cm) Bra Size/Cup Size: 32B Feet/Shoe Size: 7.5 (US) Dress Size: 4 (US) Lea Thompson Family Details: Father: Cliff Thompson Mother: Barbara Thompson Spouse/Husband: Howard Deutch (m. 1989) Children: Zoey Deutch (Daughter), Madelyn Deutch (Daughter) Siblings: Coleen Goodrich (Older Sister), Barry Thompson (Older Brother), Shannon Thompson Katona (Older Sister), Andrew Thompson (Older Brother) Others: Phillip Goodrich (Brother-in-law), Elizabeth Goodrich (Niece), Murray Deutch (Father-in-law) Partner: Dennis Quaid (1986-1989) Lea Thompson Education: Marshall-University High School, Minneapolis, MN Lea Thompson Facts: *She was born in Rochester, Minnesota on May 31, 1961. *Her parents divorced when she was six years old. *She won scholarships to the School of American Ballet and the American Ballet Theatre. *She danced in more than 45 ballets with the ABT. *She met her future husband Howard Deutch when he directed her in Some Kind of Wonderful in 1987. *Follow her on Twitter, Facebook and Instagram.
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Free Picks » NHL Picks » Detroit Red Wings vs Tampa Bay Lightning Prediction, 4/3/2021 NHL Pick, Tips and Odds Detroit Red Wings vs Tampa Bay Lightning Prediction, 4/3/2021 NHL Pick, Tips and Odds by Guy Bruhn - 4/2/2021 Game: Detroit Red Wings vs Tampa Bay Lightning Location: Amalie Arena in Tampa, FL TV: Bally Sports Detroit Odds/Point Spread: Red Wings (+336) Lightning (-389) Andrei Vasilevskiy and the Tampa Bay Lightning (25-9-2) play the Detroit Red Wings (12-21-5) at Amalie Arena on Saturday. The odds on this game have the Red Wings priced at +336 and the Lightning are at -389. The over/under has been set at 5.5. The Red Wings were on the wrong end of the scoreboard with a 3-2 defeat against the Panthers their last time on the ice. The Red Wings left a lot to be desired in terms of their offense in the loss. In the outing, they converted 2 of the 27 shots they put on goal. They also had 2 power play attempts but didn't get a goal. Detroit compiled 16 penalty minutes in this matchup. The Corsi for the Red Wings sat at 45 and the Corsi against at the end of this game was 42 which means they had a Corsi percentage of 51.7%. Their Fenwick came in at 31 and the Fenwick Against sat at 35, giving them a Fenwick percentage of 47.0%. They garnered 29 face-off victories when at even strength and were beaten on 25 opportunities to gain puck control. The offensive zone starts for them were rated at 57.4% and they had a PDO of 100.0 in this one. In regard to their scoring capabilities, the Detroit Red Wings have racked up 82 goals (29th in the league) so far this year and have allowed 122. For the current season, the have a total of 29 points and their points percentage sits at .382. Detroit comes into the game with 110 power play opportunities and they have scored 13 goals during those advantages, garnering them a rate of 11.82%. While playing at even strength, the Red Wings let the opposition score 93 goals while earning 69 of their own. Detroit has taken 1,059 shots and is the owner of a shooting percentage of 7.7%. The Red Wings have had 1,184 shots taken against them and have a save percentage of .897. Detroit Red Wings opponents have recorded 109 power play opportunities (17th in professional hockey) and have come away with 29 goals in those chances. The player guarding the cage in this matchup is Thomas Greiss. Opponents have tallied 728 goals versus Greiss in his pro hockey career and his goals against average is 2.68. Greiss has played in 305 games over the course of his professional hockey career. His save percentage sits at .913 during his 16,313 mins between the pipes. He has amassed an overall record of 139-104-33 and got the start in 267 games. From the beginning of his pro career to now, Greiss has 146 quality starts and his percentage for quality starts is .547. Greiss has seen 8,362 shot attempts taken against him and has recorded 7,634 saves. Their last time out, Tampa Bay opposed the Blue Jackets in a game where the Lightning notched a victory by a final score of 3-2. Tampa Bay wound up with a 45.9% Corsi rating. This Corsi rating is telling of the kind of game that Tampa Bay played and you could say that they played like a middle of the road team. Their Fenwick rate was 45.5% by compiling a Fenwick of 35 and the Blue Jackets having racked up a 42 Fenwick at even strength. They had a PDO of 101 and they finished the game with an oZS percentage of 48.4%. The Lightning converted 3 goals of the 34 shots on goal they tried. They had 3 power play chances in this matchup and earned 1 out of those opportunities. The Lightning have earned 94 goals at even strength and 32 goals (1st in the NHL) while having more men on the ice. Tampa Bay has taken 1,096 shots (12th in the NHL) and has earned a shooting percentage of 11.50%, while allowing the other team 1,019 shots. So far this year, the Tampa Bay Lightning have accumulated 126 goals, 52 points, in addition to a points percentage of .722. They have recorded 116 power play chances and they have accumulated a power play rate of 27.59%. They have earned a penalty kill rate of 81.97% on their opponents 122 power play tries, and their save percentage comes in at 91.6%. They have permitted 86 goals to be scored by way of 64 goals at even strength and 22 goals while they had less men on the ice. Across the ice you are likely to see Andrei Vasilevskiy in net. Teams are averaging 2.50 goals per game and he has relinquished 699 goals in total. Vasilevskiy's rate of quality starts comes out to 56.5% and he has 157 quality starting assignments in his career. He has started in 278 games and has played 16,793 mins. Vasilevskiy is the owner of a lifetime mark of 181-78-19 and has participated in 288 games. He has a tally of 8,045 saves out of the 8,744 shots attempted, giving him a percentage of .920. Who will win tonight's NHL game ATS? Guy's Pick: Take Tampa Bay (-389) Tampa Bay Lightning - Twitter Detroit Red Wings - Twitter NFL SUNDAY 6U PLAY* Expert: Raphael Esparza (VSI)
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Frankenfoot an Urban Dream Brokerage in Dunedin in 2017 which upcycles shoes into wearable art. Image: Justin Spiers. Urban Dream Brokerage helps find a space for approved projects and negotiates its use, organises a license (see below) and covers public liability insurance. Criteria: Individuals or organisations first must be satisfied they meet the criteria for application. Assessment: The applications are assessed by the UBD advisory groupl. The proposal must meet with their majority approval as to matching the criteria, and they may provide advice on its best implementation. UBD then meet with applicants to vet their application and discuss potential spaces. Location: UDB proceeds to locate property options and commence negotiations. Applicants are also encouraged to identify spaces and sites they think are suitable (in some instances they will actually negotiate the use of space themselves). If we think a project is suitable for a space that is available we meet with the applicant and assess the project in more detail. Licensing: Once located UDB issues any licenses or helps with any regulatory issues and arranges for public liability insurance cover (a key part of the brokerage's services to applicants) and assists applicants to obtain power and other utilities (we can help with set-up but the cost of power and utilities is at the licensee's cost). Monitoring: The agency then monitors the progress, and reports back to both property owners and partners at the end of the license. We will also feature applicants' projects on our website, through our newsletter to our database and through social media. Projects that aren't temporary should plan on operating on a rolling 30 day period of use. Please note we do not fund or produce your project. It is up to you to find funding and the support to make the project happen, but we can help with connections. • covers the cost of power and utilities, • obtains through UBD public liability insurance, • And takes the property on a "as is where is basis". The UDB provides to both occupiers and property owners: -brokerage of a temporary license -clearance of all permissions for use of public space -photography and documentation of the project -Public Liability Insurance for the building site up to $5 000 000 -Cover for minor damage up to $400 We ask applicants to pay what they can afford in terms of a contributory fee: $20 per week/ $50 per week/ or if they represent a small business or not for profit $100 per week. Licensees will also be liable for power and other utilities - we are able to offer assistance in getting the best deals we can on these for you. All agreements have reviews built into them. If a licensee starts a business that ends up turning over good money we'd gradually expect them to start paying closer to a commercial rent to the property owners when they can afford to. This is something we'd assist in the negotiation of. With ongoing projects, our aim is to nurture them so they eventually don't need support.
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De Blasio defends phone call to NYPD about jailed supporter Updated Feb 13, 2014 ; Posted Feb 13, 2014 By Jillian Jorgensen | jorgensen@siadvance.com de blasio.JPG Mayor Bill de Blasio, seen earlier this week delivering his State of the City address. (Associated Press) CITY HALL - It wasn't just snow - Mayor Bill de Blasio also spent time Thursday defending his phone call regarding a campaign supporter who was arrested earlier this week. "I think it's appropriate to make an inquiry," de Blasio said, seemingly over and over, with inquiry being a word he used 13 times in discussing the phone call. Bishop Orlando Findlayter, the pastor of New Hope Christian Fellowship in Brooklyn, was arrested Monday night during a traffic stop due to outstanding arrest warrants springing from civil disobedience at an immigration protest, the Wall Street Journal first reported Wednesday. That night, de Blasio made a phone call to Deputy Chief Kim Royster in the police department's press office about the arrest, the Journal reported. The precinct's commander sent Findlayter home with a desk appearance ticket by the precinct's commander - though de Blasio said he did not ask for him to be released. "I made an inquiry with Chief Royster. She came back with an answer that the situation had been settled, and I thought that the precinct inspector handled it well, and it was his choice to make," he said. He sought to emphasize he hadn't made any requests on the pastor's behalf. "This is an unusual situation where a very prominent member of the clergy, obviously, was experiencing a pretty unusual situation," he said. "So I thought it was appropriate to make an inquiry, and I got a response, and that's the end of the story. The mayor said he did not think his phone call would send police a message on how to behave in the future if a friend of his were arrested. "Everything is a case by case basis. I have tremendous respect for the NYPD and they know it, and the precinct commanders will make their best judgments and that's their jobs," de Blasio said. "So I think it's absolutely appropriate if I make an inquiry to make an inquiry and get information, but I respect that precinct commanders are going to do as they see fit."
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England finally ended their penalties curse when they beat Colombia 4-3 in a shootout after drawing their World Cup last-16 clash 1-1 following extra time after the South Americans equalised in the 93rd minute. It was the first time Colombia had been involved in a World Cup shootout and they took first blood when Jordan Henderson missed his spot kick – but for once fortune smiled on England. Earlier Harry Kane smashed in a 57th-minute penalty, his sixth goal of the tournament, and England looked to be through until Yerry Mina headed an equaliser in the third minute of stoppage time. It was England's first win in a knockout game since 2006 and earns them a quarter-final with Sweden, who were far from impressive in beating Switzerland 1-0 earlier on Tuesday. Then comes a potential semi-final against hosts Russia or Croatia with Tuesday's win appearing to vindicate – just – coach Gareth Southgate's decision to field a second-string side in the the final group game loss to Belgium to secure an easier route. Colombia's hopes suffered a huge setback before kickoff when key playmaker James Rodriguez was ruled out with a calf injury and without him they took a defensive approach and never rarely threatened. England were always the more purposeful side but they lacked the key final ball and needed a gift to take the lead. The South Americans had been getting away with blatant holding and wrestling at each of England's many corners and the referee's patience finally snapped when Carlos Sanchez hauled down tournament leading scorer Kane once too often. After four minutes of mayhem as the Colombians protested, Kane kept his cool and smashed in his third spot kick of Russia 2018. When Juan Cuadrado blazed horribly over the bar with the goal gaping 10 minutes from time with Colombia's first chance of the match it looked all over for them but there was a fiery sting in the tail of normal time. England keeper Jordan Pickford made a superb save to touch wide a furious long shot by Uribe but from the following corner – Colombia's first of the match – giant defender Mina rose highest to head in the equaliser and send the massed Colombian fans into a frenzy. England substitute Dier missed the best chance of the extra period when he headed over the bar but he made up for it in emphatic fashion with the winning penalty in the shootout.
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Global IoT Leader Lantronix to Showcase Its Latest Solutions at Ingram Micro's IoT Summit 2019 GlobeNewswire September 3, 2019 IRVINE, Calif., Sept. 03, 2019 (GLOBE NEWSWIRE) -- Lantronix, Inc. (LTRX), a global provider of secure data access and management solutions for the industrial Internet of Things (IoT), will be showcasing its latest IoT products at Ingram Micro's IoT Summit 2019. This one-day event, which takes place September 5, 2019, in Irvine, California, brings together IoT innovators with Ingram's goal of showcasing how IoT, MR, and AI are solving real business problems in today's world. Lantronix is honored to be one of the 30+ vendor partners Ingram has chosen to spotlight their solutions and will be demonstrating its latest Out-of-Band Management solutions, edge gateways as well as showcasing its IoT sensors. "We are excited to provide our partner, Ingram Micro and their customers with a view of the Lantronix Ecosystem," stated Jonathan Shipman, Lantronix VP of Strategy. "We value Ingram's vision as the World's Largest IoT Solutions Aggregator and, our synergies provide great opportunities and innovative solutions for the Ingram community." Ingram Micro's IoT Summit showcases a curated portfolio of vertically-oriented end-to-end solutions and best of breed IoT components. Lantronix will be featuring its industry-leading IoT Device Gateway family, the SGX 5150 and SGX 5150-MD IoT device gateway for medical devices. Plus introducing the newest member of the family, the SGX5150 XL, which meets the needs of customers looking for increased storage of valuable data, without the need to buy flash storage. It provides the ease of inserting and maintaining an external USB flash drive for purposes of data collection locally to the SGX 5150 XL. If you are part of the Ingram community and would like to attend the IoT Summit 2019, visit the registration page. If you're interested in learning more about Lantronix and its IoT solutions, please visit the Lantronix booth. About Ingram Micro IoT Summit This event hosted by Ingram Micro is designed exclusively for the world's largest ecosystem of reseller, system integrators and managed service providers. The objective of this one-day event is to give the Ingram community as intensive digital transformation experience without requiring too much of their customers time. This event will be held on September 5th at the Irvine Spectrum Marriott in Irvine, CA. with a planned 400 attendees and 30+ IoT vendors focused on IoT solutions for logistics, retail, building, cities, agriculture, healthcare, and industrial vertical market. About Lantronix Lantronix, Inc. is a global provider of secure data access and management solutions for the Internet of Things (IoT) assets. Our mission is to be the leading supplier of IoT solutions that enable companies to dramatically simplify the creation, deployment, and management of IoT projects while providing secure access to data for applications and people. With more than two decades of experience in creating robust machine to machine (M2M) technologies, Lantronix is an innovator in enabling our customers to build new business models and realize the possibilities of the Internet of Things. Our connectivity solutions are deployed inside millions of machines serving a wide range of industries, including industrial, medical, security, transportation, retail, financial, environmental, and government. Lantronix is headquartered in Irvine, California. For more information, visit www.lantronix.com. Learn more on the Lantronix blog, www.lantronix.com/blog, featuring industry discussion and updates. To follow Lantronix on Twitter, please visit www.twitter.com/Lantronix. View our video library on YouTube at www.youtube.com/user/LantronixInc or connect with us on LinkedIn at www.linkedin.com/company/lantronix. Lantronix Media Contact: Gail Kathryn Miller Manager, Marketing & Communications media@lantronix.com 949-453-7158 Lantronix Analyst, and Investor Contact: Jeremy Whitaker investors@lantronix.com Lantronix Sales: sales@lantronix.com America +1 (800)422-7055 (US & Canada) or +1 949-453-3990 Europe, Middle East & Africa +31 (0)76 52 36 744 Asia Pacific + 86 21-6237-8868 Japan +81 (0)50-1354-6201 India +91 994-551-2488 © 2019 Lantronix, Inc. All rights reserved. Lantronix, SGX is a trademark, of Lantronix Inc. Wi-Fi is a registered trademark of the Wi-Fi-Alliance. Other trademarks and trade names are those of their respective owners. Taiwan Semiconductor: The Dream Run May Continue Skylo raises $103 million to affordably connect the Internet of Things to satellite networks Data reveal stocks won't crash in 2020 after an insane 25% gain in 2019 Pelosi: House to send articles of impeachment to the Senate UPS, FedEx to raise fees on bulky packages The business of tattoo removal Intel reports better than expected results for Q3 Banks on pace for biggest round of job cuts in 4 years: BBG Crude spikes after Saudi drone attack; Trump orders strategic release Iranian tanker rocked by explosion off Saudi cost 'Good Place' actress Jameela Jamil on why she's 'waging war' on diet industry's 'dark side' Prince's first manager: The Taylor Swift licensing dispute is 'almost funny' U.S. hits Turkey with sanctions over Syria Yahoo Finance's most influential companies of the decade The economy still favors Trump's reelection Slack jumps after raising outlook, beating rev. estimate This Democratic presidential candidate would tax himself $16 million
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Q: How to compare the differences between 2 tiff pictures, generate a new tiff picture, and mark the differences I have two orthophoto maps (tif format) taken on different dates. How can I distinguish the differences on the two maps and mark the different points? A: try use gdal gdalcompare.py. The gdalcompare.py script compares two GDAL supported datasets and reports the differences. In addition to reporting differences to the standard output the script will also return the difference count in its exit value. enter link description here Here is a similar question
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The above Document is imported from Northwind.mdb Database (visit the Page Saving Data on Forms not in Tables for location reference of the Database) without the Page Border (Catalog Report attached to Categories Table) and drawn a double-lined Page Border with the help of Code given below. If you would like to try it out on the same Report then Import the Categories Table and the Catalog Report from Northwind.mdb database. The Code can be used on any Report that you wish to draw the Page Border and the border will be drawn within the Margin settings of the Page. Replace the name "Catalog" with the name of your Report. Print Preview or Print the Report. ' Set scale to pixels. ' Draw line as a box. When the built-in Report Wizard prepares a Report, it draws a nice Page Footer (a sample image is given below) with System Date and Number of Pages etc. ' irrespective of its current position. .ControlSource = "='Page : ' & [page] & ' / ' & [pages]" .ControlSource = "='Date : ' & Format(Date(),'dd/mm/yyyy')" The Program will check through the length of the Controls present on the Detail Section of the Report and add up the length of all fields to calculate the total length of the Page Footer. The Program assumes that the Controls are arranged close together without leaving gaps between them. Copy and paste the above code into a Global Module and save it. Run the code as you did for creating the Page Footer above. If you encounter any Error during compilation or Run time, visit the Page Command Button Animation and link the essential Library Files (7 or them) by going through the procedure explained there. Come back and re-try again. Pretty nice post. I just stumbled upon your blog and wanted to say that I have really enjoyed browsing your blog posts. In any case I'll be subscribing to your feed and I hope you write again soon!
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Notes: * The development workflow is a simplified version of the one used in [TEAMMATES](https://github.com/TEAMMATES/repo/blob/master/devdocs/process.md). * The `master` branch always contains the latest stable code (may contain unreleased features/fixes). * The `release` branch always contains the latest release version. ## Workflow for new contributors First, * Join the [contributor mailing list](https://groups.google.com/forum/#!forum/hubturbo-contributors). * Create a fork of the repo. Fixing issues: 1. Select an issue to handle. For your first issue, select an issue labelled `difficulty.beginner`. Optionally, you may discuss the issue using the issue tracker to see if your intended solution is suitable. 2. Create a branch off the current `master` named "X-short-description", where `X` is the issue number. For example, `2342-remove-println` for an issue named `Remove all unnecessary println statements`. 3. Implement your changes in the created branch. Run tests locally and ensure that there are no failures or style violations (use the `test` and `check` tasks in Gradle). 4. Push your changes to your fork. 5. Create a pull request against the [`master`](https://github.com/HubTurbo/HubTurbo) branch of the main repo. - The name of the PR should be in the format "TITLE #X", where `TITLE` is the title of the issue you selected, and `X` is its number. e.g. `Sorting order is incorrect #123` - The description of the PR should include the text "Fixes #X" e.g. `Fixes #123` [or something similar](https://github.com/blog/1506-closing-issues-via-pull-requests) to auto-close the issue when the PR is merged. - You don't have to wait until your changes are ready to do this. Feel free to use the PR to discuss any difficulties you run into, or any clarification you need. 6. After creating the PR, you can check the status of the PR on the CI (Travis) [here](https://travis-ci.org/HubTurbo/HubTurbo/pull_requests), please ensure that all tests pass without any style violations. - If your PR includes additional functional code and coverage drops, either update an existing test to test for the added/fixed functionality or add a new test. 7. When ready, get someone on the dev team to review it. You can request a review by adding a comment to the PR. 8. The reviewer will merge it when he/she is satisfied. If you need any clarification on the workflow, you may also post in the [mailing list](https://groups.google.com/forum/#!forum/hubturbo-contributors). ## Workflow for developers Similar to above, except for following differences: 1. You'll be pushing to the main repo. 2. You can also create new issues, label issues, and review code from others. 3. When creating a PR, also assing a reviewer for it. Choose another core developer as the reviewer. Try to pick one who is likely to know the code touched by the PR well. 2. When your PR is marked as `status.toMerge` by the reviewer, you should merge the PR yourself. * Merging should be done locally, not using GitHub. * Format for the merge commit: `[issue number] issue name` e.g. `[324] keyboard shortcut for creating an issue` * Ensure all tests are passing before you push the merge commit to the repo.
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Situated in Point Clear within easy reach of local amenities and approximately six miles from Clacton's Town Centre and mainline railway station is this THREE BEDROOM SEMI-DETACHED BUNGALOW benefiting from a Balcony with views over the Colne Estuary. Lounge - 14' x 12'7" (4.27m x 3.84m) - Marble hearth and surround with inset feature fire. Double glazed windows to front and side. Kitchen/Diner - 17' x 13'2" (5.18m x 4.01m) - Fitted with a range of wood laminated units at both eye and floor level. Rolled edge work surfaces with inset stainless steel single drainer sink unit. Spaces for fridge freezer, automatic washing machine and oven. Tiled splash backs. Radiator. Double glazed door to side. Further double glazed French doors and leaded light windows to rear. Bedroom One - 12'5" x 9'9" (3.78m x 2.97m) - Radiator. Double glazed leaded light window to front. Bedroom Three - 9'7" x 7'4" (2.92m x 2.24m) - Double glazed leaded light window to front. Bathroom - Fully tiled. Fitted White suite comprising panelled bath. Shower cubicle with glass door. Low level WC. Pedestal wash hand basin. Bidet. Double glazed window to rear. Balcony - 13'6" x 4'9" (4.11m x 1.45m) - Wooden base with wrought iron railings with views over Colne Estuary. Outside - Rear - Covered slabbed patio area. Raised shingle wooden borders with an array of trees. Remainder laid to artificial lawn. Fish pond. Enclosed by wooden panelled fencing.
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Weeks Automobile Corp is honored to present a wonderful example of pure vehicle design... this CERTIFIED 2013 Audi Q5 3.0T Quattro Prestige only has 34,567 miles on it and could potentially be the vehicle of your dreams! This Audi includes: MONSOON GRAY METALLIC EXTERIOR BLACK LEATHER SEATING SURFACES PRESTIGE PACKAGE AUDI ADAPTIVE LIGHT AUDI SIDE ASSIST BANG & OLUFSEN PREMIUM SOUND SYSTEM MMI NAVIGATION plus PACKAGE AUDI CONNECT SUNSHADES FOR THE REAR DOORS (MANUAL) THERMO CUPHOLDER 3.0L SUPERCHARGED 272hp TFSI V6 ENGINE w/FSI DIRECT INJECTION 8-SPEED AUTOMATIC TRANSMISSION 19 PREMIUM ALLOY WHEELS *Note - For third party subscriptions or services, please contact the dealer for more information.* This beautiful Monsoon Gray Metallic Audi Q5 3.0T Prestige qualifies for the CARFAX BuyBack Guarantee. Just say Show me the CARFAX and Weeks Automobile Corp will provide the history report for free! A test drive can only tell you so much. Get all the info when you purchase a vehicle like this with a CARFAX one-owner report. Why own a car when you can own a lifestyle? We at Weeks Automobile Corp offer you nothing less than the best with our Certified Pre-Owned vehicles. This vehicle meets Audi's highest level of standards, allowing us to provide you with what you deserve. With this exceptional SUV, you'll get sport, utility, and comfort. The Audi Q5 3.0T Prestige's pristine good looks were combined with the Audi high standard of excellence in order to make this a unique find. You'll love the feel of AWD in this 2013 Audi Q5. It provides a perfect balance of handling power and control in virtually every driving condition. Exceptional in every sense of the word, this incredibly low mileage vehicle is one of a kind. Added comfort with contemporary style is the leather interior to heighten the quality and craftsmanship for the Audi Q5 Performance, ease of use and efficiency are just a few reasons you'll love the navigation system that comes with this car. Looking f Looking forward to earning your business.
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Home / Blog Articles / What is Trenabol? Trenabol(trenbolone enanthate) is an injectable form of the strong anabolic steroid trenbolone. Given the use of an enanthate ester, this drug will exhibit virtually identical pharmacokinetics to testosterone enanthate, providing a peak release of its steroid within the first several days after injection, followed by declining levels for approximately 2 weeks. The base steroid here (trenbolone) is a derivative of nandrolone, and exhibits strong anabolic and androgenic properties. On a milligram for milligram basis it is considerably more potent than testosterone as both an anabolic and androgenic agent, though it does carry a more favorable balance (toward anabolism). Trenbolone is also unable to convert to estrogen, however it does exhibit notable progestational activity, which may mimic estrogenic side effects given the right physiological conditions. Trenbolone enanthate is virtually interchangeable with Parabolan (trenbolone hexahydrobenzylcarbonate), capable of promoting strong gains in lean muscle mass, often with an accompanying increase in relative hardness and definition. Trenbolone enanthate was never approved for use in humans. Prescribing guidelines are unavailable. Common doses for physique- and performance-enhancing purposes fall in the range of 150-300 mg per week, which is usually taken for 6-10 consecutive weeks. This level is sufficient to produce considerable increases in lean muscle mass and strength, which are usually combined with notable fat loss and increased muscle definition. As with all trenbolone injectables, this product is fairly versatile, and can be combined with many other agents depending on the desired results.
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Q: Swiper initialization not working (Cannot read property 'push' of undefined) What I'm trying to do is really simple, or so I thought. The Swiper.js API documents a boolean parameter which is called init that allows disabling the automatic initialization of the swiper. What I would like to do is define the swiper globally like so: const carousel = new Swiper(".swiper-container" , { freeMode: true, slidesPerView: "auto", init: false, }); And initialize it when a card is clicked, like so: $(".card").click(function(){ carousel.init(); }); The problem with this is that the browser throws an error and the script doesn't work. Here's the error: Cannot read property 'push' of undefined I don't know what the problem is because the Swiper API clearly states that after setting the init parameter to false, you can manually initialize it by calling carousel.init() A: It does seem that I might have solved this problem. It seems that even if you declare the swiper globally, the swiper.js can't access it for some strange reason, so I found a workaround. Maybe this is the way the designed it, but for me, at the least, it make very little sense. First, you need to declare your swiper inside a function, like so: function carouselProperties() { return new Swiper(".swiper-container", { init: false, freeMode: true, slidesPerView: "auto", }); } After that we go inside of the function in which the swiper should be called, in this case a click event listener. $(".card").click(function(){ // Here we define a variable that returns the swiper const carousel = carouselProperties() // Afte we define this variable we can finally call the init function carousel.init(); }); To recap: * *You define a function which returns the swiper and its properties. *You call that function inside all your other functions that needs to retrieve the swiper information. I hope this helped anyone with the same problem as I.
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How to setup Vyatta router bridged in VirtualBox on Windows 7 and connect another guest VM behind the Vyatta router on the VirtualBox internal network. I sometimes cut out reboot sequences and increase the video speed to help reduce overall video length.. You can add additional guests and use the IP of the Vyatta eth1 (internal int) for the gateway. VirtualBox will act as a switch. Use internal network adapters, promisc Allow VMs to communicate within VirtualBox.
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Posted on Nov 19, 2017 In Facebook, Mobile, Social Media, Technology Facebook launches Messenger Kids app – but parents vet chat contacts Facebook is launching a new version of its chat app targeting children under 13 with strict parental controls including contract approvals. The free app, called Messenger Kids, hopes to attract parents looking for a safe online chat service, with a greater level of parental control, child-friendly features, screened content and safety filters to prevent children sharing inappropriate content. Messenger Kids is a standalone app installed on the child's tablet or smartphone but controlled from a parent's Facebook account. The child does not have a Facebook account, which is prohibited for those under 13; instead, the app operates as an extension of the parent's account. Only parents have the ability to add friends or delete messages. There are no adverts or in-app purchases and the social network said the child's information will not be used for advertising purposes. Facebook also said it will not automatically move users to the regular Messenger or Facebook when they get old enough, though the company may provide them the option to move contacts to Messenger down the line. Loren Cheng, a product management director at Facebook, said: "Whether it's using video chat to talk to grandparents, staying in touch with cousins who live far away, or sending mom a decorated photo while she's working late to say hi, Messenger Kids opens up a new world of online communication to families." Children can start one-on-one or group video or text chats with approved contacts, sending videos, photos, gifs and other creative elements from a library of screened drawing tools, frames, gifs, masks, and stickers. Facebook also said that it will block children from sharing nudity, sexual or violent content, and have a dedicated moderation team to respond to flagged content. Messages sent to adults or those over 13 appear in their normal Facebook Messenger app. Parents control contacts and other options through their Facebook app on their smartphone. The app, which is rolling out as a preview to iOS with Android coming later, is only available in the US for the time being. Facebook said it was fully compliant with the US Children's Online Privacy and Protection Act, and that it had worked with online safety experts including the National PTA and Blue Star Families. Kristelle Lavallee, a children's psychology expert and content strategist at the Center on Media and Child Health at Boston Children's Hospital and Harvard University, worked with Facebook to develop the app. She said: "The risk of exposure to things [children] were not developmentally prepared for is huge." Facebook Messenger Kids "makes parents the gatekeepers" and was designed "with the best of intentions", Lavallee said. How – and if – the app ends up getting used remains to be seen. Despite US federal law prohibiting companies from collecting personal information on those under 13 years old without parental consent, millions are already on Facebook, with or without their parents' permission, says Stephen Balkam, chief executive of the nonprofit Family Online Safety Institute. He said Facebook is trying to deal with the situation pragmatically by steering young Facebook users to a service designed for them. Messenger Kids offers an opportunity to introduce children to the wider Facebook ecosystem, fending off advances from rivals targeting children and teenagers, while locking parents and family into the social network to communicate with their children.
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