pmid
int64
19.9M
38M
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int64
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[ { "contexts": [ "In this chapter, we describe a simple high-resolution technique, scanning angle interference microscopy (SAIM), for the imaging and localization of fluorescent molecules with nanometer precision along the optical axis. ", "In SAIM, samples above a reflective surface are sequentially scanned with an excitation laser at varying angles of incidence. ", "SAIM is easily implemented on widely available commercial total internal reflection fluorescence microscopes, offering potential for widespread use in cell biology. ", "Here, we describe the setup of SAIM and its application for imaging cellular structures near (<1 μm) the sample substrate." ], "name": "SAIM" }, { "contexts": [ "SAIM is easily implemented on widely available commercial total internal reflection fluorescence microscopes, offering potential for widespread use in cell biology. " ], "name": "total internal reflection fluorescence microscopes" } ]
25,065,133
2,014
[ { "contexts": [ "The species is distinguished from other members of the genus by the dimensions of its eggs and the characteristics of their surface. " ], "name": "THERM" }, { "contexts": [ "The species is distinguished from other members of the genus by the dimensions of its eggs and the characteristics of their surface. " ], "name": "THERM" }, { "contexts": [ "The species is distinguished from other members of the genus by the dimensions of its eggs and the characteristics of their surface. " ], "name": "THERM" }, { "contexts": [ "The species is distinguished from other members of the genus by the dimensions of its eggs and the characteristics of their surface. " ], "name": "THERM" } ]
25,450,245
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[ { "contexts": [ "Irregularity of the capsule edge was quantified using 2 parameters (angular second moment and contrast) using ImageJ software. " ], "name": "ImageJ" }, { "contexts": [ "Comparison of the anterior capsulotomy edge created by manual capsulorhexis and 2 femtosecond laser platforms: Scanning electron microscopy study.PURPOSE\n", "To compare the scanning electron microscopy (SEM) features of the anterior capsule edge created by continuous curvilinear capsulorhexis (CCC) and femtosecond laser-assisted capsulotomy using angular second moment and contrast.\n\n\n", "King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.\n\n\n", "Prospective comparative series.\n\n\n", "Anterior capsule specimens following CCC (n = 10) or femtosecond laser-assisted capsulotomy using 2 platforms (Lensx, n = 9, and Victus, n = 10) were studied by SEM. ", "Irregularity of the capsule edge was quantified using 2 parameters (angular second moment and contrast) using ImageJ software. ", "The clinical features and laser parameters were correlated with angular second moment and contrast.\n\n\n", "By SEM, the femtosecond laser-assisted capsulotomy edge surfaces created by both lasers showed marked irregularity compared with the smooth edge of the CCC. ", "The angular second moment and contrast measures for both lasers differed significantly from those obtained for CCC (P<.001). ", "There was no between-laser difference in angular second moment and contrast measures. ", "The angular second moment showed only a weak negative correlation with increasing laser power, whereas contrast showed a weak positive correlation with increasing power.\n\n\n", "CONCLUSIONS\n", "Both laser platforms created an irregular capsulotomy edge. ", "The angular second moment and contrast quantified capsule edge irregularities for further comparisons. ", "These measures could be used to quantify efforts to reduce capsule-edge irregularity from femtosecond laser-lens capsule interaction." ], "name": "C" } ]
24,825,029
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24,300,832
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[]
24,881,403
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[]
24,102,140
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25,189,519
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[ { "contexts": [ "Furthermore, the dual sensitive CPT-PCB lipoplexes enhanced the tumor accumulation of the two payloads and exhibited a synergistic tumor suppression effect in tumor-bearing mice in vivo, which proved to be a promising delivery system for codelivery of CPT and siPlk1 for cancer therapy." ], "name": "THERM" } ]
24,758,891
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[]
24,550,778
2,014
[]
25,012,434
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[]
25,135,613
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24,720,814
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[ { "contexts": [ "This study aimed at assessing key surface properties of agronomic relevance for products from slow pyrolysis at 250-800 °C, hydrothermal carbonization (HTC), and flash carbonization. " ], "name": "THERM" } ]
23,952,587
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[]
25,006,326
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[]
23,681,259
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[]
25,232,514
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[ { "contexts": [ "Furthermore, the transcriptional inhibition of these compounds was confirmed by a decrease in cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression levels in HepG2 cells." ], "name": "THERM" }, { "contexts": [ "Furthermore, the transcriptional inhibition of these compounds was confirmed by a decrease in cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression levels in HepG2 cells." ], "name": "THERM" }, { "contexts": [ "Furthermore, the transcriptional inhibition of these compounds was confirmed by a decrease in cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression levels in HepG2 cells." ], "name": "THERM" } ]
25,099,948
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[]
25,442,497
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[ { "contexts": [ "The aim of this review was to compare the efficiency of cone beam computed tomography (CBCT) and conventional intraoral radiography for the detection of vertical root fractures (VRFs).\n\n\n", "Data from comparative and noncomparative studies investigating CBCT, conventional radiography, or both for the diagnosis of VRFs were searched. ", "No superiority of CBCT compared with conventional radiography was found for VRF detection. " ], "name": "CBCT" }, { "contexts": [ "The aim of this review was to compare the efficiency of cone beam computed tomography (CBCT) and conventional intraoral radiography for the detection of vertical root fractures (VRFs).\n\n\n", "Data from comparative and noncomparative studies investigating CBCT, conventional radiography, or both for the diagnosis of VRFs were searched. ", "No superiority of CBCT compared with conventional radiography was found for VRF detection. " ], "name": "CBCT" }, { "contexts": [ "The aim of this review was to compare the efficiency of cone beam computed tomography (CBCT) and conventional intraoral radiography for the detection of vertical root fractures (VRFs).\n\n\n", "Data from comparative and noncomparative studies investigating CBCT, conventional radiography, or both for the diagnosis of VRFs were searched. ", "No superiority of CBCT compared with conventional radiography was found for VRF detection. " ], "name": "CBCT" }, { "contexts": [ "The aim of this review was to compare the efficiency of cone beam computed tomography (CBCT) and conventional intraoral radiography for the detection of vertical root fractures (VRFs).\n\n\n" ], "name": "conventional intraoral radiography" }, { "contexts": [ "The aim of this review was to compare the efficiency of cone beam computed tomography (CBCT) and conventional intraoral radiography for the detection of vertical root fractures (VRFs).\n\n\n", "Data from comparative and noncomparative studies investigating CBCT, conventional radiography, or both for the diagnosis of VRFs were searched. ", "No superiority of CBCT compared with conventional radiography was found for VRF detection. " ], "name": "CBCT" } ]
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[ { "contexts": [ "We use molecular dynamics simulations to study the nature of interactions between the side chain pairs ALA-PHE, SER-ASN, and LYS-GLU in bulk water and in water-filled nanopores. " ], "name": "molecular dynamics simulations" }, { "contexts": [ "The temperature dependence of the bulk solvent potentials of mean force and the interaction free energies in cylindrical and spherical nanopores is used to identify the corresponding entropic and enthalpic components. " ], "name": "The temperature dependence of the bulk solvent potentials of mean force and the interaction free energies in cylindrical and spherical nanopores" } ]
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[ { "contexts": [ "Furthermore, continuing exercise during infectious diseases may lead to prolongation or aggravation of illness with severe acute or chronic organ manifestations. " ], "name": "THERM" }, { "contexts": [ "Furthermore, continuing exercise during infectious diseases may lead to prolongation or aggravation of illness with severe acute or chronic organ manifestations. " ], "name": "THERM" }, { "contexts": [ "Furthermore, continuing exercise during infectious diseases may lead to prolongation or aggravation of illness with severe acute or chronic organ manifestations. " ], "name": "THERM" } ]
24,092,841
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[]
24,931,737
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25,696,999
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25,350,849
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[ { "contexts": [ "Olig3 is not involved in the ventral patterning of spinal cord.At embryonic stages, Olig3 is initially expressed in the dorsal-most region of the spinal cord, but later in the ventral marginal zone as well. ", "Previous studies indicated that Olig3 controlled the patterning of dorsal spinal cord and loss of Olig3 function led to the re-specification of dI2 and dI3 neurons into dI4 interneurons. ", "However, the role of Olig3 in regulating the development of ventral spinal cord has remained unknown. ", "BrdU labeling demonstrated that ventral Olig3 was expressed in the post-mitotic neurons and Olig3+ cells seen at late embryonic stages were born at the earlier stage but remained in the marginal zone throughout embryogenesis. ", "Loss-of-function and gain-of-function experiment indicated that Nkx2.2 regulated the expression of Olig3 in V3 interneurons. ", "However, Olig3 mutation didn't apparently affect the generation and migration of ventral neurons. ", "These findings suggest that Olig3 plays different roles in regulating the development of dorsal and ventral spinal cord." ], "name": "Olig3" }, { "contexts": [ "BrdU labeling demonstrated that ventral Olig3 was expressed in the post-mitotic neurons and Olig3+ cells seen at late embryonic stages were born at the earlier stage but remained in the marginal zone throughout embryogenesis. " ], "name": "BrdU" }, { "contexts": [ "Loss-of-function and gain-of-function experiment indicated that Nkx2.2 regulated the expression of Olig3 in V3 interneurons. " ], "name": "Nkx2.2" } ]
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[ { "contexts": [ "Pramipexole alters thermoregulation in restless legs syndrome.STUDY OBJECTIVES\n", "Previous studies have associated restless legs syndrome (RLS) with peripheral hypoxia and impaired thermoregulation in the lower extremities. ", "Pramipexole, however, alters thermoregulation and the previous studies might have been biased by medication. " ], "name": "THERM" } ]
25,309,350
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24,323,716
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24,643,240
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25,282,523
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24,717,943
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24,646,730
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[ { "contexts": [ "A new automated electrochemiluminescence immunoassay (ECLIA) for CsA measurement has been assessed in a multicenter evaluation.\n\n\n", "External quality control sample recovery by ECLIA was 93%-114% of LC-MS/MS sample recovery. ", "Deming regression analysis of ECLIA method comparison to combined LC-MS/MS results yielded a slope of 1.04 [95% confidence interval (CI), 1.03-1.06] and intercept of 2.8 mcg/L (95% CI, 1.5-4.1 mcg/L). ", "The data from this multicenter evaluation indicate that the new ECLIA-based cyclosporine assay is fit for its purpose, the therapeutic monitoring of CsA." ], "name": "ECLIA" }, { "contexts": [ "External quality control sample recovery by ECLIA was 93%-114% of LC-MS/MS sample recovery. ", "Deming regression analysis of ECLIA method comparison to combined LC-MS/MS results yielded a slope of 1.04 [95% confidence interval (CI), 1.03-1.06] and intercept of 2.8 mcg/L (95% CI, 1.5-4.1 mcg/L). " ], "name": "LC-MS/MS" }, { "contexts": [ "In addition, comparisons to liquid chromatography-tandem mass spectrometry methods in routine use at each investigational site and to commercial chemiluminescent microparticle immunoassay and antibody-conjugated magnetic immunoassay methods were performed.\n\n\n", "Comparison to chemiluminescent microparticle immunoassay yielded a slope of 0.87 (95% CI, 0.85-0.89) and intercept of 1.4 mcg/L (95% CI, -0.89 to 3.7 mcg/L); comparison to antibody-conjugated magnetic immunoassay yielded a slope of 0.96 (95% CI, 0.93-0.98) and intercept of -4.2 mcg/L (95% CI, -7.1 to -1.2 mcg/L).\n\n\n" ], "name": "chemiluminescent microparticle immunoassay" }, { "contexts": [ "In addition, comparisons to liquid chromatography-tandem mass spectrometry methods in routine use at each investigational site and to commercial chemiluminescent microparticle immunoassay and antibody-conjugated magnetic immunoassay methods were performed.\n\n\n", "Comparison to chemiluminescent microparticle immunoassay yielded a slope of 0.87 (95% CI, 0.85-0.89) and intercept of 1.4 mcg/L (95% CI, -0.89 to 3.7 mcg/L); comparison to antibody-conjugated magnetic immunoassay yielded a slope of 0.96 (95% CI, 0.93-0.98) and intercept of -4.2 mcg/L (95% CI, -7.1 to -1.2 mcg/L).\n\n\n" ], "name": "antibody-conjugated magnetic immunoassay" } ]
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[ { "contexts": [ "Furthermore, a functionalisation of porphyrin derivatives was investigated by placing divalent ions in the centre of these systems. " ], "name": "THERM" } ]
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[ { "contexts": [ "Furthermore, current molecular testing of tumors at the genomic or transcriptomic level are very indirect measures of biological response to a drug, particularly for small molecule inhibitors that target kinases. " ], "name": "THERM" } ]
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[ { "contexts": [ "Continuing professional development of dentists through distant learning: an Indira Gandhi National Open University-Dental Council of India experiment a report.To keep themselves updated with all the advancements in the field of dentistry, dentists should involve themselves in some kind of professional development. ", "Indira Gandhi National Open University in collaboration with Dental Council of India (DCI) developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics) and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. " ], "name": "Indira Gandhi National Open University" }, { "contexts": [ "Continuing professional development of dentists through distant learning: an Indira Gandhi National Open University-Dental Council of India experiment a report.To keep themselves updated with all the advancements in the field of dentistry, dentists should involve themselves in some kind of professional development. ", "Indira Gandhi National Open University in collaboration with Dental Council of India (DCI) developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics) and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. " ], "name": "Dental Council of India" }, { "contexts": [ "Indira Gandhi National Open University in collaboration with Dental Council of India (DCI) developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics) and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. ", "The training is conducted in premiere dental colleges and institutions recognized by DCI. " ], "name": "DCI" }, { "contexts": [ "Indira Gandhi National Open University in collaboration with Dental Council of India (DCI) developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics) and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. " ], "name": "Endodontics" }, { "contexts": [ "Indira Gandhi National Open University in collaboration with Dental Council of India (DCI) developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics) and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. " ], "name": "oral implantology" } ]
24,823,849
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24,385,257
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24,087,923
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[ { "contexts": [ "The ICF-CY-based structural equation model of factors associated with participation in children with autism.OBJECTIVE\n", "The aim of this study was to apply the International Classification of Functioning, Disability and Health - Child and Youth (ICF-CY) framework to identify the factors related to the participation of children with autism.\n\n\n", "The raters collected data using the ICF-CY-based questionnaire as an instrument to construct the structural equation modeling of factors associated with participation.\n\n\n" ], "name": "ICF-CY" }, { "contexts": [ "The ICF-CY-based structural equation model of factors associated with participation in children with autism.OBJECTIVE\n" ], "name": "ICF-CY-based structural equation model" }, { "contexts": [ "The raters collected data using the ICF-CY-based questionnaire as an instrument to construct the structural equation modeling of factors associated with participation.\n\n\n" ], "name": "ICF-CY-based questionnaire" } ]
23,744,084
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24,646,440
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25,327,619
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[]
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[]
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[]
25,348,653
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[]
25,279,256
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26,988,331
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[ { "contexts": [ "Rapid Golgi analysis method for efficient and unbiased classification of dendritic spines.Dendritic spines are the primary recipients of excitatory synaptic input in the brain. " ], "name": "Rapid Golgi analysis method" }, { "contexts": [ "One of the most commonly used methods to visualize spines is Golgi-Cox staining, which is appealing both due to ease of sample preparation and wide applicability to multiple species including humans. " ], "name": "Golgi-Cox staining" } ]