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[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['An', '8-year-old', 'boy', 'consults', 'for', 'the', 'appearance', 'of', 'pubic', 'hair', 'at', 'the', 'base', 'of', 'the', 'penis', 'for', 'the', 'last', '12', 'months.'], ['The', 'testicle', 'has', 'not', 'increased', 'in', 'volume', 'and', 'the', 'penis', 'has', 'not', 'increased', 'in', 'size.'], ['There', 'is', 'no', 'increase', 'in', 'growth', 'rate', 'in', 'the', 'last', 'year.'], ['The', 'bone', 'age', 'is', 'one', 'year', 'older', 'than', 'the', 'chronological', 'age.'], ['What', 'is', 'the', 'most', 'likely', 'diagnosis?'], ['1-', 'Central', 'precocious', 'puberty.'], ['2-', 'Peripheral', 'precocious', 'puberty.'], ['3-', 'Early', 'adrenarche.'], ['4-', 'Adrenal', 'tumor.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['In', 'the', 'male,', 'the', 'onset', 'of', 'puberty', 'is', 'considered', 'normal', 'from', 'the', 'age', 'of', '9', 'years,', 'therefore', 'in', 'this', 'case', 'it', 'is', 'a', 'premature', 'puberty.'], ['The', 'onset', 'of', 'puberty', 'is', 'defined', 'as', 'an', 'increase', 'in', 'testicular', 'volume', '(greater', 'than', 'or', 'equal', 'to', '4cc);', 'by', 'specifying', 'that', 'the', 'testicular', 'size', 'has', 'not', 'increased,', 'we', 'can', 'rule', 'out', 'options', '1', 'and', '2.'], ['The', 'excessive', 'secretion', 'of', 'androgens', 'produced', 'by', 'an', 'adrenal', 'tumor', 'would', 'cause', 'a', 'greater', 'amount', 'of', 'hair', 'and', 'an', 'increase', 'in', 'penile', 'size,', 'which', 'our', 'patient', 'does', 'not', 'present.'], ['Therefore,', 'the', 'correct', 'option', 'is', 'early', 'adrenarche.']]
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300_106
[['QUESTION', 'TYPE:', 'INFECTIOUS', 'DISEASES'], ['CLINICAL', 'CASE:'], ['A', '32-year-old', 'man', 'from', 'Cameroon', 'consults', 'for', 'fever', 'cough', 'and', 'left', 'hemithorax', 'pain', 'of', '1', "month's", 'evolution.'], ['He', 'took', 'amoxicillin-clavulanic', 'acid', 'for', '1', 'week', 'without', 'improvement', 'of', 'symptoms.'], ['A', 'blood', 'test', 'showed', 'a', 'white', 'blood', 'cell', 'count', 'of', '8000/microL', 'and', 'a', 'hemoglobin', 'of', '12.8', 'g/dL.'], ['Chest', 'X-ray', 'showed', 'a', 'loculated', 'left', 'pleural', 'effusion', 'occupying', 'one', 'third', 'of', 'the', 'hemithorax.'], ['A', 'thoracentesis', 'shows', 'a', 'yellowish', 'fluid', 'with', 'the', 'following', 'features:', 'red', 'blood', 'cells', '2000/uL,', 'leukocytes', '2500/uL,', 'with', '90%', 'lymphocytes,', 'protein', '4.9', 'g/dL,', 'lactate', 'dehydrogenase', '550', 'U/L,', 'glucose', '67', 'mg/dL,', 'and', 'absence', 'of', 'malignant', 'cells', 'on', 'cytology.'], ['Which', 'of', 'the', 'following', 'tests', 'would', 'be', 'most', 'useful', 'in', 'diagnosing', 'the', 'cause', 'of', 'the', 'pleural', 'effusion?'], ['1-', 'A', 'thoracic', 'computed', 'tomography', '(CT)', 'scan.'], ['2-', 'Pleural', 'fluid', 'pH', 'measurement.'], ['3-', 'Measurement', 'of', 'adenosine', 'deaminase', 'in', 'pleural', 'fluid.'], ['4-', 'Tuberculin', 'test.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['The', 'determination', 'of', 'ADA,', 'in', 'the', 'presence', 'of', 'a', 'pneumonia', 'of', 'long', 'evolution', 'that', 'does', 'not', 'improve', 'with', 'antibiotic', 'treatment,', 'with', 'an', 'effusion', 'with', 'abundant', 'leukocytes', 'and', 'lymphocytic', 'predominance,', 'in', 'which', 'the', 'presence', 'of', 'neoplasia', 'is', 'ruled', 'out,', 'with', 'values', 'higher', 'than', '70', 'UI/L,', 'should', 'lead', 'us', 'to', 'have', 'a', 'high', 'degree', 'of', 'suspicion', 'about', 'tuberculous', 'etiology', 'and', 'send', 'the', 'pleural', 'fluid', 'to', 'microbiology', 'for', 'tuberculosis', 'study.']]
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434_119
[['QUESTION', 'TYPE:', 'INFECTIOUS', 'DISEASES', 'AND', 'MICROBIOLOGY'], ['CLINICAL', 'CASE:'], ['A', '38-year-old', 'woman', 'of', 'veterinary', 'profession,', 'in', 'charge', 'of', 'monitoring', 'wild', 'animals', 'and', 'assisting', 'in', 'the', 'delivery', 'of', 'domestic', 'livestock.'], ['She', 'starts', 'with', 'a', 'high', 'fever', 'with', 'chills,', 'headache,', 'myalgia', 'and', 'non-productive', 'cough', 'that', 'she', 'interprets', 'as', 'a', 'flu-like', 'process.'], ['She', 'presented', 'with', 'chest', 'pain.'], ['Chest', 'X-ray', 'showed', 'bilateral', 'pulmonary', 'infiltrates', 'in', 'lower', 'fields.'], ['A', 'serologic', 'test', 'was', 'performed', 'with', 'elevated', 'antibody', 'titers', 'against', 'phase', 'I', 'antigens.'], ['Which', 'of', 'the', 'following', 'statements', 'is', 'TRUE?'], ['1-', 'The', 'way', 'of', 'transmission', 'of', 'this', 'entity', 'is', 'by', 'ticks.'], ['2-', 'Both', 'doxycycline', 'and', 'hydroxychloroquine', 'are', 'effective', 'in', 'treating', 'acute', 'forms', 'of', 'this', 'disease.'], ['3-', 'In', 'its', 'acute', 'form', 'it', 'also', 'presents,', 'generally,', 'elevation', 'of', 'antibodies', 'against', 'phase', 'I', 'antigens.'], ['4-', 'Mortality', 'in', 'acute', 'forms', 'is', 'almost', 'nonexistent.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['Acute', 'infection', 'by', 'Coxiella', 'burnetii', 'manifested', 'in', 'this', 'case', 'by', 'Pneumonia.'], ['Coxiella', 'infection', 'is', 'not', 'transmitted', 'by', 'ticks.'], ['The', 'contact', 'can', 'be', 'with', 'high', 'probability', 'at', 'the', 'time', 'of', 'delivery', 'of', 'an', 'infected', 'farm', 'animal,', 'in', 'which', 'the', 'bacterium', 'is', 'disseminated', 'in', 'aerosols.'], ['The', 'treatment', 'of', 'choice', 'is', 'with', 'doxycycline', 'in', 'the', 'acute', 'phase', '(if', 'meningitis', 'is', 'present,', 'quinolones', 'are', 'preferred', 'due', 'to', 'penetration', 'of', 'the', 'blood-brain', 'barrier).'], ['The', 'combination', 'of', 'doxycycline', 'plus', 'hicroxychloroquine', 'can', 'be', 'used,', 'but', 'for', 'chronic', 'Q', 'fever', '(which', 'is', 'where', 'elevation', 'of', 'antibodies', 'against', 'phase', 'I', 'antigens', 'is', 'observed', 'and', 'carries', 'a', 'higher', 'risk', 'of', 'mortality).']]
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563_175
[['QUESTION', 'TYPE:', 'PREVENTIVE', 'MEDICINE'], ['CLINICAL', 'CASE:'], ['A', '62-year-old', 'patient', 'who', 'consults', 'because', 'of', 'close', 'contact', 'in', 'recent', 'weeks', 'with', 'a', 'person', 'with', 'active', 'tuberculosis.'], ['Mantoux', 'test', 'is', 'positive', '(12', 'mm).'], ['His', 'history', 'includes', 'treatment', 'with', 'oral', 'anticoagulants', '(acenocoumarol)', 'for', 'a', 'deep', 'vein', 'thrombosis', 'a', 'few', 'months', 'ago.'], ['He', 'does', 'not', 'report', 'fever', 'or', 'cough', 'and', 'is', 'asymptomatic.'], ['Chest', 'X-ray', 'is', 'normal.'], ['Which', 'of', 'the', 'following', 'treatments', 'is', 'the', 'most', 'advisable?'], ['1-', 'Isoniazid,', 'for', 'nine', 'months.'], ['2-', 'Rifampicin,', 'for', 'four', 'months.'], ['3-', 'Isoniazid', 'and', 'rifampicin,', 'for', 'three', 'months.'], ['4-', 'Isoniazid', 'and', 'rifapentine,', 'for', 'three', 'months.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['As', 'of', '2018,', 'there', 'are', 'four', 'dosing', 'schedules', 'for', 'treatment', 'of', 'latent', 'TB', 'infection', 'recommended', 'by', 'the', 'CDC', 'using', 'isoniazid', '(INH),', 'rifapentine', '(RPT)', 'or', 'rifampin', '(RIF).'], ['All', 'treatments', 'are', 'effective.'], ['Health', 'care', 'providers', 'should', 'prescribe', 'the', 'shorter', 'treatments,', 'which', 'are', 'more', 'convenient,', 'whenever', 'possible.'], ['The', 'shortest', 'combination', 'would', 'be', 'Isoniazid', '+', 'Rifapentine', 'for', 'three', 'months', 'or', 'Rifampicin', 'for', 'four', 'months.'], ['However,', 'the', 'fact', 'that', 'he', 'is', 'taking', 'acenocoumarol', 'means', 'that', 'the', 'indication', 'for', 'this', 'patient', 'is', 'Isoniazid', 'for', '9', 'months,', 'since', 'there', 'is', 'interaction', 'between', 'the', 'rifamycin', 'derivatives', '(rifapentine', 'and', 'rifampicin).']]
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89_57
[['QUESTION', 'TYPE:', 'CARDIOLOGY', 'AND', 'VASCULAR', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '64-year-old', 'man', 'consults', 'for', 'right', 'calf', 'pain', 'when', 'climbing', 'hills', 'and', 'stairs', 'and', 'when', 'walking', 'on', 'level', 'ground', 'for', 'a', 'prolonged', 'period', 'of', 'time.'], ['He', 'reports', 'that', 'the', 'pain', 'becomes', 'so', 'intense', 'with', 'exertion', 'that', 'he', 'is', 'forced', 'to', 'stand', 'up,', 'which', 'causes', 'the', 'pain', 'to', 'improve', 'in', 'a', 'matter', 'of', 'minutes.'], ['As', 'personal', 'history,', 'the', 'patient', 'is', 'a', 'smoker', 'of', '20', 'cigarettes', 'a', 'day,', 'diabetic', 'on', 'metformin', 'and', 'hypertensive.'], ['On', 'examination,', 'there', 'is', 'good', 'peripheral', 'perfusion', 'of', 'the', 'right', 'foot,', 'but', 'the', 'patient', 'has', 'a', 'decreased', 'pedal', 'pulse.'], ['Which', 'of', 'the', 'following', 'complementary', 'tests', 'should', 'be', 'ordered', 'initially', 'for', 'the', 'diagnosis', 'and', 'assessment', 'of', 'the', 'severity', 'of', 'the', "patient's", 'disease?'], ['1-', 'Arteriography', 'of', 'lower', 'extremities.'], ['2-', 'Ankle-brachial', 'index.'], ['3-', 'Computerized', 'axial', 'tomography', 'with', 'vascular', 'reconstruction', 'of', 'lower', 'extremities.'], ['4-', 'Tape', 'stress', 'test.'], ['5-', 'Magnetic', 'resonance', 'imaging.'], ['CORRECT', 'ANSWER:', '2'], ['Although', 'the', 'diagnosis', 'of', 'peripheral', 'arteriopathy', 'is', 'fundamentally', 'clinical', '(in', 'this', 'patient', 'the', 'picture', 'is', 'very', 'typical),', 'we', 'can', 'objectively', 'assess', 'the', 'severity', 'of', 'the', 'disease', 'with', 'the', 'use', 'of', 'bloodless', 'techniques.'], ['The', 'most', 'important', 'is', 'the', 'ankle-brachial', 'index.'], ['Therefore,', 'answer', '2', 'is', 'correct.'], ['Imaging', 'techniques', '(arteriography,', 'angioCT', 'or', 'angioMRI)', 'are', 'used', 'when', 'surgical', 'repair', 'of', 'arterial', 'occlusion', 'is', 'considered.']]
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586_75
[['QUESTION', 'TYPE:', 'OBSTETRICS', 'AND', 'GYNECOLOGY'], ['CLINICAL', 'CASE:'], ['A', '30-year-old', 'woman', 'requesting', 'a', 'contraceptive', 'method.'], ['She', 'has', 'a', 'history', 'of', 'an', 'emergency', 'cesarean', 'section', '7', 'months', 'ago,', 'giving', 'birth', 'to', 'a', '3,550', 'g', 'baby', 'girl.'], ['She', 'is', 'exclusively', 'breastfeeding.'], ['Point', 'out', 'the', 'correct', 'statement:'], ['1-', 'Explain', 'to', 'her', 'that,', 'if', 'she', 'is', 'amenorrheic,', 'she', 'does', 'not', 'require', 'another', 'contraceptive', 'method', 'since', 'breastfeeding', 'is', 'sufficient', 'as', 'a', 'contraceptive', 'method.'], ['2-', 'He', 'informed', 'her', 'that', 'the', 'levonogestrel', 'IUD', 'is', 'contraindicated', 'because', 'she', 'had', 'a', 'cesarean', 'section', 'less', 'than', 'a', 'year', 'ago.'], ['3-', 'He', 'explains', 'that', 'she', 'could', 'use', 'a', 'gestagen-only', 'hormonal', 'method.'], ['4-', 'She', 'is', 'offered', 'combined', 'hormonal', 'contraception.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['Given', 'her', 'circumstances', 'and', 'taking', 'into', 'account', 'that', 'she', 'is', 'exclusively', 'breastfeeding,', 'the', 'best', 'thing', 'to', 'do', 'would', 'be', 'to', 'prescribe', 'only', 'gestagens.']]
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461_148
[['QUESTION', 'TYPE:', 'OPHTHALMOLOGY', '(ECTOPIC)'], ['CLINICAL', 'CASE:'], ['A', '59-year-old', 'woman', 'with', 'recent', 'onset', 'of', 'epileptic', 'seizures', 'comes', 'to', 'the', 'emergency', 'department.'], ['On', 'examination', 'she', 'presents', 'left', 'pyramidal', 'signs', 'and', 'papillary', 'edema.'], ['A', 'brain', 'MRI', 'shows', 'a', 'right', 'hemispheric', 'mass', 'with', 'edema,', 'midline', 'deviation', 'and', 'signs', 'of', 'tentorial', 'herniation.'], ['She', 'reports', 'that', 'for', 'the', 'past', 'week', 'she', 'has', 'been', 'suffering', 'from', 'headache', 'that', 'has', 'been', 'progressing', 'in', 'intensity.'], ['Which', 'of', 'the', 'following', 'features', 'associated', 'with', 'headache', 'seems', 'most', 'likely', 'for', 'this', 'patient?'], ['1-', 'Morning', 'predominance.'], ['2-', 'It', 'does', 'not', 'change', 'with', 'effort.'], ['3-', 'Photophobia.'], ['4-', 'Sonophobia.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['It', 'is', 'a', 'headache', 'in', 'the', 'context', 'of', 'papilledema.'], ['In', 'this', 'case', 'the', 'papilledema', 'is', 'due', 'to', 'increased', 'intracranial', 'pressure', 'due', 'to', 'a', 'tumor.'], ['The', 'headache', 'due', 'to', 'increased', 'intracranial', 'pressure', 'is', 'of', 'positional', 'type', '(it', 'increases', 'with', 'Valsalva', 'maneuvers', 'and', 'when', 'bending', 'down),', 'so', 'option', '2', 'is', 'not', 'correct.'], ['In', 'addition,', 'it', 'is', 'predominantly', 'morning', '(option', '1', 'is', 'correct)', 'because', 'in', 'the', 'morning', 'intracranial', 'pressure', 'naturally', 'rises.'], ['Migraine-type', 'headaches', 'may', 'be', 'associated', 'with', 'photophobia', 'or', 'sonophobia', '(answers', '3', 'and', '4).'], ['But', 'this', 'headache', 'is', 'not', 'a', 'migraine', 'headache.']]
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547_125
[['QUESTION', 'TYPE:', 'CARDIOLOGY'], ['CLINICAL', 'CASE:'], ['A', '23-year-old', 'male', 'diagnosed', 'with', 'Wolff-Parkinson-White', 'syndrome', 'who', 'comes', 'to', 'the', 'emergency', 'department', 'for', 'palpitations.'], ['The', 'ECG', 'shows', 'an', 'irregular', 'wide', 'QRS', 'tachycardia,', 'with', 'a', 'heart', 'rate', 'of', '205', 'bpm,', 'compatible', 'with', 'pre-excited', 'atrial', 'fibrillation.'], ['Which', 'of', 'the', 'following', 'drugs', 'do', 'you', 'consider', 'appropriate', 'to', 'stop', 'the', 'tachycardia:'], ['1-', 'Verapamil.'], ['2-', 'Digoxin.'], ['3-', 'Adenosine.'], ['4-', 'Procainamide.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['Procainamide.'], ['The', 'treatment', 'of', 'choice', 'for', 'Wolff-Parkinson-White', 'syndrome', 'is', 'cardioversion', 'with', 'direct', 'current.'], ['Heart', 'rate', 'slowing', 'drugs,', 'commonly', 'used', 'in', 'atrial', 'fibrillation,', 'are', 'ineffective,', 'and', 'digoxin', 'and', 'non-dihydropyridine', 'calcium', 'channel', 'blockers', '(e.g.,', 'verapamil,', 'diltiazem)', 'are', 'contraindicated', 'because', 'they', 'may', 'increase', 'the', 'ventricular', 'rate', 'and', 'cause', 'ventricular', 'fibrillation.'], ['If', 'cardioversion', 'is', 'not', 'possible,', 'drugs', 'that', 'prolong', 'the', 'refractory', 'period', 'of', 'accessory', 'connection', 'should', 'be', 'used.'], ['IV', 'procainamide', 'or', 'amiodarone', 'is', 'preferred,', 'but', 'any', 'class', 'Ia,', 'Ic', 'or', 'III', 'antiarrhythmic', 'drug', 'can', 'be', 'used.']]
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193_161
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['In', 'a', '3-month-old', 'infant', 'all', 'the', 'clinical', 'manifestations', 'outlined', 'below', 'would', 'make', 'it', 'necessary', 'to', 'rule', 'out', 'cystic', 'fibrosis,', 'EXCEPT:'], ['1-', 'Delayed', 'meconium', 'evacuation.'], ['2-', 'Salty', 'taste', 'of', 'the', 'skin.'], ['3-', 'Isolation', 'of', 'secretions', 'of', 'Pseudomonas', 'aeruginosa.'], ['4-', 'Deterioration/detention', 'of', 'the', 'weight', 'curve.'], ['5-', 'Hypernatremic', 'dehydration.'], ['CORRECT', 'ANSWER:', '5'], ['Dehydration', 'may', 'be', 'due', 'to', 'diarrhea', 'of', 'other', 'etiologies.'], ['I', 'have', 'doubts', 'about', 'answer', '3', 'since', 'it', 'does', 'not', 'specify', 'which', 'secretions', 'are', 'involved.'], ['We', 'have', 'to', 'understand', 'that', 'the', 'growth', 'of', 'Pseudomona', 'aeruginosa', 'is', 'in', 'the', 'culture', 'of', 'bronchial', 'secretions.'], ['Because', 'clearly', 'the', 'indication', 'to', 'perform', 'a', 'sweat', 'chlorine', '(to', 'rule', 'out', 'FQP)', 'are', 'the', 'HIPOnatremic', 'dehydrations', 'and', 'not', 'the', 'hypernatremic', 'ones', 'as', 'the', 'answer', 'says.']]
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431_116
[['QUESTION', 'TYPE:', 'INFECTIOUS', 'DISEASES', 'AND', 'MICROBIOLOGY'], ['CLINICAL', 'CASE:'], ['A', '38-year-old', 'man', 'comes', 'to', 'the', 'emergency', 'department', 'with', 'fever', 'above', '39ºC', 'and', 'deterioration', 'of', 'consciousness', 'after', 'a', 'trip', 'to', 'Equatorial', 'Guinea', 'without', 'antimalarial', 'prophylaxis.'], ['Laboratory', 'tests', 'showed', 'creatinine', '3.4', 'mg/dL,', 'AST', '764', 'UlL,', 'ALT', '678', 'UlL.'], ['The', 'laboratory', 'reports', 'the', 'visualization', 'of', 'Plasmodium', 'falciparum', 'in', 'the', 'blood', 'with', 'a', 'parasitemia', 'level', 'of', '6%.'], ['What', 'treatment', 'would', 'you', 'initiate', 'at', 'this', 'time?'], ['1-', 'Mefloquine', 'orally.'], ['2-', 'Intravenous', 'artesunate.'], ['3-', 'Doxycycline', 'orally.'], ['4-', 'Oral', 'quinine', 'sulfate.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['In', 'severe', 'cases', 'of', 'Plasmodium', 'infection,', 'the', 'greatest', 'risk', 'of', 'mortality', 'occurs', 'in', 'the', 'first', '24', 'hours', 'of', 'clinical', 'presentation,', 'so', 'treatment', 'should', 'be', 'started', 'immediately.'], ['Treatment', 'with', 'parenteral', 'or', 'intramuscular', 'artesunate', 'is', 'more', 'indicated', 'in', 'severe', 'Plasmodium', 'infection,', 'both', 'in', 'adults', 'and', 'children', 'and', 'in', 'pregnant', 'women.']]
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569_152
[['QUESTION', 'TYPE:', 'NEPHROLOGY'], ['CLINICAL', 'CASE:'], ['24-year-old', 'male', 'presenting', 'with', 'dysmorphic', 'microhematuria,', 'proteinuria', 'of', '3', 'g/24', 'h,', 'eGFR', '(CKD-EPI)', '85', 'ml/min', 'and', 'sensorineural', 'hearing', 'loss.'], ['He', 'reports', 'that', 'his', 'maternal', 'grandmother', 'required', 'dialysis', 'at', '70', 'years', 'of', 'age', 'and', 'both', 'his', 'mother', 'and', 'younger', 'sister', 'have', 'isolated', 'microhematuria.'], ['Which', 'of', 'the', 'following', 'diseases', 'is', 'more', 'likely?'], ['1-', 'Alport', 'syndrome.'], ['2-', 'IgA', 'nephropathy.'], ['3-', 'Fabry', 'disease.'], ['4-', 'Autosomal', 'dominant', 'polycystic', 'kidney', 'disease.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['Textbook', 'case,', 'little', 'to', 'add.'], ['Microhematuria,', 'proteinuria', 'and', 'sensorineural', 'hearing', 'loss', 'in', 'a', 'young', 'male', 'with', 'a', 'family', 'history', 'of', 'women', 'with', 'hematuria', '=', 'Alport', 'syndrome.']]
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501_76
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['A', '5-year-old', 'boy', 'diagnosed', 'with', 'chronic', 'renal', 'failure.'], ['He', 'comes', 'to', 'the', 'emergency', 'department', 'with', 'vomiting,', 'malaise,', 'and', 'palpitations.'], ['An', 'electrocardiogram', 'was', 'performed', 'with', 'T-wave', 'elevation', 'and', 'blood', 'tests', 'showed', 'potassium', 'levels', 'of', '5.9', 'mEq/L.'], ['Immediate', 'administration', 'of', 'calcium', 'gluconate', 'is', 'decided.'], ['What', 'is', 'the', 'purpose', 'of', 'this', 'treatment?'], ['1-', 'Encourage', 'the', 'displacement', 'of', 'potassium', 'from', 'the', 'plasma', 'space', 'to', 'the', 'intracellular', 'space.'], ['2-', 'Chelate', 'circulating', 'potassium', 'to', 'favor', 'its', 'hepatic', 'elimination.'], ['3-', 'Chelate', 'circulating', 'potassium', 'to', 'favor', 'its', 'renal', 'elimination.'], ['4-', 'Antagonize', 'the', 'action', 'of', 'potassium', 'on', 'the', 'myocardial', 'cell', 'membrane.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['Calcium', 'gluconate', 'has', 'no', 'effect', 'on', 'blood', 'potassium', 'levels', '(therefore', 'options', '1,', '2', 'and', '3', 'are', 'ruled', 'out).'], ['Its', 'function', 'is', 'to', 'decrease', 'the', 'excitability', 'of', 'cardiac', 'myocytes', 'to', 'decrease', 'the', 'likelihood', 'of', 'developing', 'heart', 'rhythm', 'disorders.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
242_111
[['QUESTION', 'TYPE:', 'INFECTIOUS', 'DISEASES'], ['CLINICAL', 'CASE:'], ['A', '50-year-old', 'man', 'with', 'chronic', 'bronchitis', 'is', 'admitted', 'for', 'pneumonia', 'with', 'positive', 'blood', 'culture', 'for', 'Streptococcus', 'pneumoniae,', 'with', 'an', 'MIC', 'to', 'penicillin', 'of', '0.0125', 'mg/l.'], ['Treatment', 'was', 'started', 'with', 'penicillin', '2', 'million', 'every', '4h.'], ['On', 'the', 'fifth', 'day,', 'she', 'still', 'has', 'a', 'fever', 'of', '38ºC.'], ['Which', 'of', 'the', 'following', 'decisions', 'do', 'you', 'think', 'is', 'correct?'], ['1-', 'I', 'would', 'change', 'the', 'treatment', 'to', 'ceftriaxone', 'because', 'of', 'its', 'greater', 'efficacy.'], ['2-', 'I', 'would', 'add', 'a', 'quinolone', 'to', 'the', 'treatment.'], ['3-', 'I', 'would', 'switch', 'to', 'amoxicillin/clavulanic', 'acid.'], ['4-', 'It', 'would', 'rule', 'out', 'the', 'presence', 'of', 'pleural', 'empyema.'], ['5-', 'I', 'would', 'continue', 'with', 'the', 'same', 'treatment,', 'assuming', 'it', 'is', 'simply', 'a', 'timing', 'issue.'], ['CORRECT', 'ANSWER:', '4'], ['The', 'patient', 'is', 'a', 'man', 'with', 'pneumonia', 'with', 'isolated', 'germ', 'in', 'blood', 'culture', 'and', 'antibiogram.'], ['According', 'to', 'the', 'data', 'provided,', 'it', 'is', 'a', 'pneumococcus', 'sensitive', 'to', 'penicillin', '(MIC', '<', '0.125),', 'so', 'treatment', 'is', 'started', 'with', 'penicillin', 'at', 'high', 'doses', 'every', '4', 'h,', 'despite', 'which', 'the', 'fever', 'persists.'], ['If', 'we', 'analyze', 'the', 'case', 'carefully,', 'the', 'treatment', 'should', 'be', 'effective', 'since', 'the', 'germ', 'is', 'totally', 'sensitive', 'to', 'the', 'drug', 'and', 'the', 'dosage', 'is', 'adequate', '(so', 'that', 'high', 'concentrations', 'of', 'the', 'drug', 'should', 'be', 'maintained', 'at', 'all', 'times,', 'remember', 'that', 'the', 'efficacy', 'of', 'beta-lactams', 'is', 'time-dependent', 'and', 'the', 'antibiotic', 'concentrations', 'in', 'blood', 'should', 'be', 'above', 'the', 'MIC', 'permanently', 'to', 'achieve', 'effectiveness', 'and', 'avoid', 'the', 'production', 'of', 'resistance).'], ['In', 'such', 'a', 'case,', 'what', 'could', 'be', 'happening,', 'probably,', 'although', 'the', 'antibiotic', 'is', 'the', 'right', 'one,', 'it', 'is', 'not', 'reaching', 'the', 'infectious', 'focus', 'adequately', 'because', 'an', 'empyema', 'has', 'probably', 'occurred.'], ['We', 'should', 'rule', 'out', 'the', 'existence', 'of', 'an', 'empyema', 'and', 'drain', 'it', 'while', 'continuing', 'with', 'the', 'antibiotic', 'treatment.'], ['If', 'the', 'dosage', 'had', 'not', 'been', 'adequate', 'and', 'the', 'presence', 'of', 'drug', 'resistance', 'was', 'possible,', 'one', 'option', 'could', 'have', 'been', 'to', 'treat', 'with', 'ceftriaxone', 'at', 'high', 'doses,', 'since', 'we', 'should', 'remember', 'that', 'streptococcus', 'does', 'not', 'produce', 'beta-lactamase', 'and', 'beta-lactam', 'resistance', 'is', 'produced', 'by', 'another', 'mechanism', '(using', 'amoxicillin-clavulanate', 'would', 'not', 'provide', 'us', 'with', 'anything).'], ['With', 'quinolone', 'we', 'do', 'not', 'increase', 'the', 'spectrum', 'and', 'it', 'is', 'evident', 'that', 'the', 'poor', 'evolution', 'of', 'the', 'patient', 'is', 'not', 'only', 'a', 'problem', 'of', 'time.']]
[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Marker', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
487_68
[['QUESTION', 'TYPE:', 'GENETICS'], ['CLINICAL', 'CASE:'], ['What', 'genetic', 'and', 'reproductive', 'counseling', 'would', 'you', 'indicate', 'to', 'a', '30-year-old', 'woman', 'who', 'consults', 'because', 'she', 'is', 'a', 'carrier', 'of', 'a', 'premutation', 'in', 'the', 'FMR1', 'gene,', 'responsible', 'for', 'Fragile', 'X', 'syndrome,', 'and', 'who', 'wishes', 'to', 'have', 'offspring.'], ['Point', 'out', 'the', 'correct', 'answer:'], ['1-', 'All', 'her', 'male', 'children', 'will', 'be', 'carriers', 'and,', 'therefore,', 'will', 'manifest', 'the', 'disease.'], ['2-', 'There', 'is', 'a', 'phenomenon', 'of', 'genetic', 'anticipation,', 'so', 'their', 'offspring', 'will', 'present', 'more', 'severe', 'and', 'earlier', 'symptoms.'], ['3-', 'Preimplantation', 'genetic', 'diagnosis', 'for', 'sex', 'selection', 'of', 'embryos', 'by', 'fluorescence', 'in', 'situ', 'hybridization', '(FISH)', 'is', 'the', 'best', 'option', 'for', 'healthy', 'offspring.'], ['4-', '50%', 'of', 'her', 'daughters', 'will', 'be', 'carriers,', 'but', 'will', 'not', 'present', 'clinical', 'manifestations', 'of', 'the', 'disease.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['Another', 'classic', 'MIR,', 'asked', 'in', '2019', 'and', 'in', '2017,', 'fragile', 'X', 'syndrome.'], ['Also,', 'on', 'the', 'same', 'concept', 'as', 'question', '44,', 'the', 'phenomenon', 'of', 'genetic', 'anticipation.'], ['Triplet', 'expansion', 'diseases,', 'such', 'as', 'this', 'one,', 'can', 'have', 'the', 'anticipation', 'phenomenon', 'whereby', 'females', 'with', 'premutations', '(between', '55-200', 'repeats)', 'can', 'have', 'children', 'with', 'full', 'mutations', '(more', 'than', '200', 'repeats', 'of', 'the', 'triplet)', 'and', 'more', 'obvious,', 'more', 'severe', 'and/or', 'earlier', 'clinical,', 'in', 'both', 'males', 'and', 'females', '(Fragile', 'X', 'syndrome,', 'early', 'ovarian', 'failure,', 'tremor/ataxia', 'associated', 'with', 'Fragile', 'X).']]
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364_176
[['QUESTION', 'TYPE:', 'HEMATOLOGY'], ['CLINICAL', 'CASE:'], ['A', '78-year-old', 'woman', 'with', 'a', 'history', 'of', 'type', '2', 'diabetes', 'treated', 'with', 'oral', 'antidiabetics,', 'hypertension', 'treated', 'with', 'beta-blockers', 'and', 'ACE', 'inhibitors,', 'and', 'NYHA', 'grade', '1', 'congestive', 'heart', 'failure', 'with', 'LVEF', 'of', '48%,', 'and', 'currently', 'asymptomatic.'], ['Functional', 'status:', 'ECOG', '0.'], ['History', 'of', '2', 'years', 'of', 'evolution', 'of', 'small', 'lumps', 'in', 'the', 'neck.'], ['Biopsy', 'of', 'cervical', 'adenopathy:', 'follicular', 'lymphoma', 'grade', '2.'], ['Extension', 'study:', 'Hb', '12', 'g/dL,', 'Leukocytes', '6,900/microL', '(Neutrophils', '60%,', 'Lymphocytes', '27%,', 'Monocytes', '6%,', 'Eosinophils', '4%,', 'Basophils', '4%),', 'Platelets', '220,000/microL.'], ['MO:', 'infiltrate', 'by', 'follicular', 'lymphoma.'], ['Creatinine', '1.5', 'mg/dL,', 'LDH', '235', 'U/L,', 'Beta2', 'microglobulin', '2.1', 'microg/mL.'], ['CT:', 'lymphadenopathies', 'less', 'than', '3', 'cm', 'in', 'cervical,', 'axillary,', 'retroperitoneal,', 'iliac', 'and', 'inguinal', 'territories;', 'liver', 'and', 'spleen', 'are', 'normal.'], ['Which', 'of', 'the', 'following', 'treatments', 'is', 'the', 'most', 'appropriate?'], ['1-', 'Rituximab-CHOP', '(Cyclophosphamide,', 'Adriamycin,', 'Vincristine,', 'Prednisone).'], ['2-', 'Rituximab-CVP', '(Cyclophosphamide,', 'Vincristine,', 'Prednisone).'], ['3-', 'Do', 'not', 'treat', 'and', 'monitor', '(wait', 'and', 'see).'], ['4-', 'Rituxirnab-Bendamustine.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['There', 'may', 'be', 'debate', 'about', 'whether', 'to', 'start', 'Rituximab', 'with', 'another', 'cytostatic', 'drug', 'or', 'in', 'monotherapy,', 'but', 'given', 'the', 'lack', 'of', 'survival', 'benefit', 'with', 'early', 'initiation', 'of', 'treatment,', 'the', 'NCCN', 'guidelines', 'recommend', 'waiting', 'and', 'seeing,', 'unless', 'GELF', 'criteria', 'are', 'met', 'to', 'initiate', 'treatment:', 'GELF', 'criteria', '(Follicular', 'Lymphoma', 'Study', 'Group):', '-', 'Involvement', 'of', '≥3', 'nodal', 'areas,', 'each', 'with', 'a', 'diameter', '≥', '3', 'cm.'], ['-', 'Any', 'nodal', 'or', 'extranodal', 'mass', 'with', 'a', 'diameter', '≥', '7', 'cm.'], ['-', 'B', 'symptoms.'], ['-', 'Splenomegaly.'], ['-', 'Pleural', 'effusion', 'or', 'ascites.'], ['-', 'Cytopenias', '(leukocytes', '<', '1.0', 'x', '109', '/', 'L', 'and/or', 'platelets', '<', '100', 'x', '109', '/', 'L).'], ['-', 'Leukemia', '(>', '5.0', 'x', '109', '/L', 'of', 'malignant', 'cells).']]
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90_32
[['QUESTION', 'TYPE:', 'GENERAL', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '35-year-old', 'woman', 'is', 'diagnosed', 'with', 'colon', 'cancer', 'located', 'in', 'the', 'hepatic', 'angle.'], ['She', 'has', 'a', 'family', 'history', 'of', 'colon', 'cancer', 'in', 'her', 'mother,', 'an', 'aunt', 'at', 'the', 'age', 'of', '45', 'and', 'a', 'grandfather.'], ['The', 'most', 'accepted', 'surgical', 'intervention', 'is:'], ['1-', 'Right', 'hemicolectomy.'], ['2-', 'Extended', 'right', 'hemicolectomy.'], ['3-', 'Subtotal', 'colectomy.'], ['4-', 'Total', 'colectomy', 'with', 'ileorectal', 'anatomosis.'], ['5-', 'Total', 'colectomy', 'with', 'ileoanal', 'anatomy.'], ['CORRECT', 'ANSWER:', '4'], ['The', 'statement', 'with', 'the', 'family', 'history', 'indicates', 'that', 'this', 'is', 'a', 'case', 'of', 'hereditary', 'nonpolyposis', 'colorectal', 'cancer', '(Lynch', 'syndrome).'], ['The', 'age', 'and', 'right', 'location', 'data', 'lead', 'us', 'to', 'answer', '4:', 'total', 'colectomy', 'with', 'ileorectal', 'anastomosis.'], ['If', 'a', 'conventional', 'right', 'hemicolectomy', 'type', 'surgery', 'is', 'performed,', 'the', 'chances', 'of', 'recurrence', 'are', 'higher', 'than', '30%.'], ['Excision', 'of', 'the', 'rectum', 'is', 'not', 'necessary', 'prophylactically.']]
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528_134
[['QUESTION', 'TYPE:', 'NEPHROLOGY'], ['CLINICAL', 'CASE:'], ['53-year-old', 'woman', 'with', 'a', 'personal', 'history', 'of', 'obesity', 'and', 'migraine.'], ['Her', 'blood', 'pressure', 'has', 'been', 'taken', 'repeatedly', 'at', 'the', "doctor's", 'and', "nurse's", 'office,', 'presenting', 'figures', 'below', '140/90', 'mmHg.'], ['However,', 'an', 'approved', 'blood', 'pressure', 'measuring', 'device', 'has', 'been', 'purchased', 'and', 'she', 'has', 'been', 'taught', 'how', 'to', 'use', 'it', 'correctly.'], ['He', 'comes', 'in', 'showing', 'blood', 'pressure', 'recordings', 'taken', 'at', 'home', 'over', 'several', 'weeks', 'with', 'values', 'above', '140/90', 'mmHg.'], ['Mark', 'the', 'correct', 'answer:'], ['1-', 'She', 'has', 'secondary', 'hypertension.'], ['2-', 'Presents', 'masked', 'arterial', 'hypertension.'], ['3-', 'Presents', 'isolated', 'clinical', 'hypertension.'], ['4-', 'Presents', 'refractory', 'arterial', 'hypertension.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['The', 'patient', 'described', 'is', 'the', 'definition', 'of', 'masked', 'HT,', 'normal', 'figures', 'in', 'consultation', 'and', 'elevated', 'on', 'AMPA', 'or', 'ABPM', '(option', '2', 'correct).'], ['It', 'is', 'not', 'secondary', 'HT', 'because', 'no', 'study', 'has', 'been', 'done', 'to', 'confirm', 'it', '(option', '1', 'incorrect).'], ['It', 'is', 'not', 'isolated', 'HT', 'because', 'the', 'elevated', 'figures', 'are', 'maintained', 'for', 'several', 'weeks', '(option', '3', 'incorrect).'], ['It', 'is', 'not', 'refractory', 'HT', 'because', 'it', 'has', 'not', 'yet', 'been', 'treated', '(option', '4', 'incorrect).']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim']]
583_70
[['QUESTION', 'TYPE:', 'OBSTETRICS', 'AND', 'GYNECOLOGY'], ['CLINICAL', 'CASE:'], ['A', '43-year-old', 'woman', 'with', 'a', 'levonorgestrel', 'intrauterine', 'device', 'who', 'consults', 'for', 'lack', 'of', 'rest', 'at', 'night', 'with', 'the', 'appearance', 'of', 'heat', 'and', 'palpitations.'], ['In', 'the', 'analytical', 'analysis', 'highlights', 'free', 'T4', '10.5', 'pmol/L', '(9-19),', 'thyrotropin', '2.1', 'mIU/L', '(0.30-5.00),', 'FSH', '95.6', 'IU/L', '(1.38-16.7),', 'LH', '21', 'IU/L', '(2.4-9.3),', 'estradiol', '<', '0.07', 'nmol/L', '(0.07', '-', '1.14).'], ['What', 'is', 'the', 'most', 'appropriate', 'treatment?'], ['1-', 'Benzodiazepines.'], ['2-', 'Vaginal', 'estrogens.'], ['3-', 'Oral', 'estrogens', 'and', 'progestogens', 'in', 'continuous', 'regimen.'], ['4-', 'Transdermal', 'estrogens', 'in', 'a', 'continuous', 'regimen.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['The', 'hormonal', 'profile', 'we', 'are', 'told', 'is', 'in', 'menopausal', 'range', '(FSH', '>20;', 'estradiol', '<5)', 'and', 'the', 'patient', 'has', 'systemic', 'vasomotor', 'symptoms.'], ['Therefore,', 'it', 'would', 'be', 'more', 'appropriate', 'to', 'administer', 'systemic', 'estrogens.'], ['To', 'compensate,', 'she', 'already', 'has', 'a', 'local', 'uterine', 'progestin', '(levonorgestrel', 'IUD).']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]
195_163
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['A', '15-month-old', 'boy,', 'who', 'during', 'dinner,', 'after', 'eating', 'a', 'bite', 'of', 'tortilla,', 'suddenly', 'presented', 'with', 'facial', 'reddening', 'predominantly', 'perioral,', 'habonous', 'lesions', 'on', 'the', 'trunk', 'and', 'extremities', 'and', 'cough.'], ['On', 'arrival', 'at', 'the', 'center,', 'the', 'patient', 'was', 'conscious', 'and,', 'in', 'addition', 'to', 'what', 'was', 'described', 'above,', 'the', 'following', 'were', 'observed:', 'suprasternal', 'twitching,', 'abundant', 'watery', 'rhinorrhea,', 'bilateral', 'hypoventilation', 'without', 'wheezing', 'and', 'capillary', 'refill', 'of', 'less', 'than', '2', 'seconds.'], ['Of', 'the', 'following', 'statements,', 'indicate', 'the', 'CORRECT', 'answer:'], ['1-', 'The', 'priority', 'is', 'to', 'cannulate', 'a', 'venous', 'line.'], ['2-', 'Intramuscular', 'methylprednisolone', 'is', 'the', 'treatment', 'of', 'choice.'], ['3-', 'It', 'is', 'a', 'picture', 'of', 'urticaria', 'associated', 'with', 'asthma,', 'and', 'should', 'be', 'treated', 'with', 'antihistamines', 'and', 'inhaled', 'bronchodilators.'], ['4-', 'Parents', 'should', 'be', 'advised', 'to', 'transfer', 'to', 'a', 'hospital', 'emergency', 'department.'], ['5-', 'Intramuscular', 'adrenaline', 'should', 'be', 'administered', 'without', 'further', 'delay.'], ['CORRECT', 'ANSWER:', '5'], ['She', 'is', 'describing', 'egg', 'anaphylaxis,', 'a', 'potentially', 'fatal', 'condition.'], ['The', 'treatment', 'of', 'choice', 'is', 'intramuscular', 'adrenaline,', 'and', 'effectively,', 'without', 'wasting', 'too', 'much', 'time.'], ['The', 'first', 'thing', 'is', 'INTRAMUSCULAR', 'adrenaline', 'NOW!'], ['The', 'venous', 'route,', 'corticosteroids,', 'antihistamines,', 'etc.', 'will', 'come', 'later.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
84_49
[['QUESTION', 'TYPE:', 'CARDIOLOGY', 'AND', 'VASCULAR', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '75-year-old', 'man,', 'hypertensive', 'and', 'dyslipidemic', 'with', 'a', 'history', 'of', 'heart', 'failure', 'due', 'to', 'left', 'ventricular', 'systolic', 'dysfunction', '(EF', '<', '30%).'], ['He', 'comes', 'to', 'our', 'office', 'for', 'worsening', 'of', 'his', 'usual', 'dyspnea', 'in', 'recent', 'weeks.'], ['His', 'systolic', 'blood', 'pressure', 'is', '160/95', 'mmHg', 'with', 'a', 'heart', 'rate', 'of', '65', 'bpm.'], ['In', 'the', 'physical', 'examination', 'no', 'crackles', 'were', 'heard', 'and', 'his', 'jugular', 'venous', 'pressure', 'was', 'normal.'], ['He', 'provides', 'a', 'creatinine', 'determination', 'that', 'is', '3.7', 'mg/dL', 'with', 'ions', 'within', 'normal.'], ['Which', 'of', 'the', 'following', 'drugs', 'is', 'the', 'most', 'appropriate', 'to', 'improve', 'the', 'prognosis', 'of', 'his', 'heart', 'failure?'], ['1-', 'Enalapril.'], ['2-', 'Losartan.'], ['3-', 'Spironolactone.'], ['4-', 'Bisoprolol.'], ['5-', 'Eplerenone.'], ['CORRECT', 'ANSWER:', '4'], ['In', 'a', 'patient', 'with', 'multiple', 'CVRF', 'with', 'concomitant', 'heart', 'and', 'renal', 'failure', '(presumably', 'of', 'multiple', 'etiology:', 'renal', 'hypoperfusion,', 'arteriosclerosis...),', 'we', 'must', 'be', 'very', 'careful', 'when', 'using', 'diuretics', 'and', 'ACEI/ARA-II,', 'since', 'we', 'can', 'worsen', 'renal', 'function', 'and/or', 'increase', 'potassium', 'levels', '(among', 'diuretics,', 'spironolactone', 'and', 'eplerenone', 'are', '"potassium-sparing").'], ['Therefore,', 'in', 'this', 'case', 'we', 'will', 'use', 'bisoprolol.']]
[['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
427_95
[['QUESTION', 'TYPE:', 'ENDOCRINOLOGY'], ['CLINICAL', 'CASE:'], ['A', '45-year-old', 'woman', 'comes', 'to', 'the', 'emergency', 'department', 'with', 'confusional', 'symptoms', 'accompanied', 'by', 'dysphonia.'], ['On', 'examination', 'she', 'has', 'a', 'palpable', 'neck', 'mass', 'and', 'a', 'blood', 'test', 'shows', 'plasma', 'calcium', 'levels', 'of', '15', 'mg/dL', '(normal', 'up', 'to', '10.2', 'mg/dL).'], ['Given', 'these', 'findings,', 'which', 'of', 'the', 'following', 'diagnoses', 'should', 'be', 'suspected?'], ['1-', 'Parathyroid', 'carcinoma.'], ['2-', 'Medullary', 'thyroid', 'carcinoma.'], ['3-', 'MEN', 'type', 'I.'], ['4-', 'Parathyroid', 'adenoma.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['Palpable', 'mass', 'in', 'the', 'neck:', 'suspect', 'thyroid/parathyroid', 'pathology.'], ['It', 'is', 'associated', 'with', 'hypercalcemia,', 'therefore,', 'the', 'option', 'of', 'medullary', 'thyroid', 'cancer', 'is', 'ruled', 'out', '(it', 'does', 'not', 'affect', 'the', 'level', 'of', 'calcemia).'], ['To', 'think', 'of', 'MEN', 'type', 'I', 'we', 'should', 'associate', 'other', 'pathologies', '(pituitary,', 'pancreatic', 'or', 'duodenal', 'tumors).'], ['The', 'presence', 'of', 'a', 'calcemia', 'higher', 'than', '13mgr/dl,', 'together', 'with', 'dysphonia,', 'indicates', 'a', 'malignant', 'tumor', '(higher', 'calcemia', 'level', 'and', 'infiltration),', 'therefore', 'we', 'opt', 'for', 'option', '1.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
462_151
[['QUESTION', 'TYPE:', 'OPHTHALMOLOGY', '(ECTOPIC)'], ['CLINICAL', 'CASE:'], ['A', '13-year-old', 'boy', 'presents', 'with', 'subacute', 'headache', 'and', 'diplopia.'], ['Neurologic', 'examination', 'shows', 'vertical', 'gaze', 'palsy', 'and', 'MRI', 'shows', 'a', 'contrast-enhancing', 'lesion', 'in', 'the', 'pineal', 'region', 'obstructing', 'the', 'aqueduct', 'of', 'Sylvian.'], ['The', 'most', 'likely', 'diagnosis', 'is:'], ['1-', 'Glioblastoma.'], ['2-', 'Medulloblastoma.'], ['3-', 'Germ', 'cell', 'tumor.'], ['4-', 'Meningioma.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['Diplopia', 'is', 'usually', 'caused', 'by', 'acute', 'or', 'secondary', 'strabismus.'], ['Vertical', 'gaze', 'palsy', 'is', 'due', 'to', 'a', 'midbrain', 'lesion.'], ['In', 'this', 'case', 'the', 'MRI', 'already', 'places', 'the', 'origin', 'of', 'the', 'symptoms', 'in', 'the', 'pineal', 'gland.'], ['The', 'most', 'frequent', 'tumor', 'in', 'this', 'region', 'is', 'the', 'germ', 'cell', 'tumor', '(answer', '3).']]
[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
557_168
[['QUESTION', 'TYPE:', 'ENDOCRINOLOGY'], ['CLINICAL', 'CASE:'], ['58-year-old', 'male,', 'obese,', 'asymptomatic,', 'moderate', 'drinker,', 'who', 'presents', 'a', 'first', 'baseline', 'blood', 'glucose', 'of', '153', 'mg/d', 'with', 'negative', 'glycosuria.'], ['In', 'the', 'following', 'weeks', 'he', 'has', 'had', 'two', 'other', 'baseline', 'blood', 'glucose', 'readings', 'of', '118', 'and', '136', 'mg/dl.'], ['Which', 'of', 'the', 'following', 'is', 'the', 'most', 'appropriate', 'approach', 'to', 'confirm', 'the', 'diagnosis', 'of', 'diabetes', 'mellitus:'], ['1-', 'Practice', 'a', 'blood', 'glucose', 'curve', 'with', '75', 'g', 'of', 'glucose.'], ['2-', 'Already', 'meets', 'diagnostic', 'criteria', 'for', 'diabetes', 'mellitus.'], ['3-', 'Request', 'a', 'determination', 'of', 'basal', 'insulinemia', 'or', 'C-peptide.'], ['4-', 'Request', 'a', 'determination', 'of', 'glycosylated', 'hemoglobin.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['Diagnostic', 'Criteria', 'for', 'DM', 'according', 'to', 'ISPAD', '2018', '*Classic', 'symptoms', 'of', 'diabetes', 'with', 'blood', 'glucose', '>', '200mgr/dl', 'or:', '*', 'Fasting', 'glycemia', '≥', '126mgr/dl', '(fasting', 'at', 'least', '8h)', 'or', '*', 'Glycemia', 'at', '2h', 'SOG', '≥', '200mgr/dl', '(on', '2', 'occasions)', 'or', '*', 'HbA1C', '≥', '6.5%.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
35_68
[['QUESTION', 'TYPE:', 'NEUROLOGY', 'AND', 'NEUROSURGERY'], ['CLINICAL', 'CASE:'], ['A', '56-year-old', 'patient', 'with', 'no', 'personal', 'or', 'family', 'history', 'of', 'interest', 'is', 'studied', 'because', 'he', 'has', 'been', 'having', 'difficulty', 'walking', 'with', 'his', 'right', 'leg', 'for', 'six', 'months.'], ['He', 'reports', 'no', 'other', 'symptoms.'], ['The', 'examination', 'shows', 'a', '4/5', 'weakness', 'for', 'dorsal', 'flexion', 'and', 'eversion', 'of', 'the', 'foot', 'and', '4/5', 'for', 'flexion', 'and', 'inversion', 'of', 'the', 'foot,', 'with', 'increased', 'muscle', 'reflexes', 'and', 'Babinski', 'present,', 'the', 'rest', 'being', 'normal.'], ['The', 'syndromic', 'diagnosis', 'would', 'be:'], ['1-', 'Mononeuropathy', 'of', 'the', 'right', 'common', 'peroneal', 'nerve.'], ['2-', 'Focal', 'involvement', 'of', 'the', 'first', 'motor', 'neuron', 'and', 'probably', 'of', 'the', 'second.'], ['3-', 'Right', 'hemimedullary', 'involvement', '(Brown-Sequard).'], ['4-', 'Multiple', 'mononeuropathy', 'with', 'involvement', 'of', 'the', 'common', 'peroneal', 'and', 'right', 'posterior', 'tibial', 'nerve.'], ['5-', 'Right', 'lumbar', 'plexopathy.'], ['CORRECT', 'ANSWER:', '2'], ['Answer', '1', 'incorrect:', 'It', 'does', 'not', 'explain', 'pyramidalism.'], ['Answer', '2', 'correct:', 'A', 'nonspecific', 'answer,', 'but', 'probably', 'the', 'correct', 'answer.'], ['Answer', '3', 'incorrect:', 'We', 'would', 'lack', 'data', 'to', 'think', 'of', 'a', 'Brown', 'Sequard', 'hemimedullary', 'syndrome.'], ['It', 'would', 'explain', 'the', 'pyramidalism,', 'but', 'we', 'would', 'be', 'missing', 'data', 'suggestive', 'of', 'this', 'picture', 'such', 'as', 'a', 'contralateral', 'hypoesthesia.'], ['Incorrect', 'answer', '4:', 'It', 'could', 'explain', 'the', 'difficulty', 'in', 'dorsiflexion', 'and', 'plantar', 'flexion', 'of', 'the', 'foot,', 'but', 'not', 'the', 'pyramidalism.'], ['Incorrect', 'answer', '5:', 'In', 'a', 'similar', 'way', 'to', 'the', 'previous', 'one,', 'it', 'could', 'explain', 'part', 'of', 'the', 'clinical', 'picture,', 'but', 'not', 'the', 'pyramidalism.']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]
271_170
[['QUESTION', 'TYPE:', 'ANESTHESIOLOGY', 'AND', 'CRITICAL', 'CARE'], ['CLINICAL', 'CASE:'], ['An', '80-year-old', 'man', 'comes', 'to', 'your', 'office', 'for', 'evaluation', 'of', 'a', 'scheduled', 'cholecystectomy', 'by', 'laparoscopy.'], ['He', 'has', 'a', 'history', 'of', 'arterial', 'hypertension', 'under', 'treatment', 'for', '10', 'years.'], ['He', 'denies', 'heart', 'or', 'pulmonary', 'disease.'], ['She', 'has', 'no', 'chest', 'pain.'], ['She', 'has', 'an', 'active', 'life', 'and', 'goes', 'daily', 'to', 'the', 'gym', 'where', 'she', 'alternates', 'swimming', 'and', 'walking', 'on', 'the', 'treadmill', 'for', 'at', 'least', 'one', 'hour.'], ['Usual', 'treatment:', 'nebivolol', '5', 'mg', 'every', '24', 'hours', 'and', 'hydrochlorothiazide', '12.5', 'mg', 'daily.'], ['Physical', 'examination:', 'weight', '73', 'kgs;', 'height', '179', 'cm;', 'blood', 'pressure', '138/80', 'mmHg;', 'heart', 'rate', '60', 'beats/minute.'], ['No', 'murmurs', 'are', 'auscultated', 'Which', 'of', 'the', 'following', 'is', 'the', 'most', 'appropriate', 'preoperative', 'approach?'], ['1-', 'Perform', 'a', 'stress', 'test.'], ['2-', 'Perform', 'echocardiography'], ['3-', 'Perform', 'a', 'thallium', 'and', 'dipyridamole', 'scan.'], ['4-', 'Perform', 'electrocardiogram.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['This', 'is', 'a', 'completely', 'gratuitous', 'question,', 'from', 'a', 'healthier', 'gentleman', 'than', 'me', 'who', 'is', 'going', 'to', 'undergo', 'low-risk', 'surgery', 'on', 'a', 'scheduled', 'basis.'], ['The', 'answer', 'is', 'obviously', '4.'], ['Had', 'there', 'been', 'a', 'fifth', 'option', 'it', 'would', 'have', 'been', 'that', 'nothing', 'needs', 'to', 'be', 'done,', 'which', 'might', 'have', 'generated', 'some', 'doubt', 'in', 'the', 'student,', 'but', 'since', 'the', 'question', 'does', 'not', 'exist', 'it', 'is', 'a', 'piece', 'of', 'candy.'], ['Although', 'there', 'are', 'many', 'protocols', 'on', 'preoperative', 'procedures,', 'almost', 'as', 'many', 'as', 'there', 'are', 'hospitals,', 'the', 'question', 'makes', 'it', 'easy', 'by', 'putting', 'a', 'very', 'old', 'patient,', '80', 'years', 'old.'], ['The', 'age', 'range', 'from', 'which', 'it', 'is', 'considered', 'mandatory', 'to', 'request', 'an', 'ECG', 'varies', 'between', '45,', '50,', '60', 'or', 'even', 'some', 'say', '70', 'years.'], ['For', 'example:', '>', '50', 'years:', 'always,', 'except', 'if', 'a', 'previous', 'ECG', 'is', 'available', '<', '50', 'years:', 'only', 'if', 'there', 'is', 'known', 'or', 'suspected', 'heart', 'disease', '(CVRF),', 'severe', 'DM,', 'hyperthyroidism', 'or', 'severe', 'COPD.']]
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306_207
[['QUESTION', 'TYPE:', 'OPHTHALMOLOGY'], ['CLINICAL', 'CASE:'], ['A', '34-year-old', 'patient', 'playing', 'tennis', 'is', 'hit', 'by', 'a', 'tennis', 'ball', 'in', 'the', 'left', 'orbit.'], ['On', 'examination', 'he', 'presents', 'significant', 'palpebral', 'hematoma,', 'hyposphagmia,', 'diplopia', 'to', 'the', 'upper', 'vision', 'with', 'limitation', 'of', 'the', 'upper', 'version', 'of', 'the', 'eyeball.'], ['What', 'would', 'you', 'suspect?'], ['1-', 'Fracture', 'of', 'the', 'inferior', 'wall', 'of', 'the', 'floor', 'of', 'the', 'orbit', 'with', 'entrapment', 'of', 'the', 'inferior', 'rectus', 'muscle.'], ['2-', 'Zygomatic', 'arch', 'fracture.'], ['3-', 'Fracture', 'of', 'the', 'superior', 'wall', 'of', 'the', 'orbit', 'with', 'entrapment', 'of', 'the', 'superior', 'rectus', 'muscle.'], ['4-', 'Dentoalveolar', 'fracture.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['The', 'statement', 'describes', 'diplopia', 'to', 'superior', 'vision', 'with', 'limitation', 'of', 'upper', 'eyeball', 'extension.'], ['As', 'the', 'mechanical', 'function', 'of', 'the', 'left', 'inferior', 'rectus', 'is', 'compromised,', 'it', 'would', 'not', 'allow', 'to', 'complete', 'the', 'supraduccion', 'movement', 'generating', 'vertical', 'diplopia,', 'this', 'plus', 'the', 'traumatic', 'antecedent', 'allows', 'to', 'suspect', 'a', 'fracture', 'of', 'the', 'orbital', 'floor', 'with', 'muscular', 'entrapment', 'of', 'the', 'inferior', 'rectus.'], ['Fracture', 'of', 'the', 'roof', 'is', 'much', 'less', 'frequent', 'and', 'the', 'entrapment', 'of', 'the', 'superior', 'rectus', 'would', 'cause', 'limitation', 'for', 'infraduction.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
328_83
[['QUESTION', 'TYPE:', 'ENDOCRINOLOGY'], ['CLINICAL', 'CASE:'], ['A', '49-year-old', 'man', 'who', 'consults', 'for', 'severe', 'polyuria', 'and', 'polydipsia', 'and', 'unintentional', 'weight', 'loss', 'of', '10', 'kg', 'and', 'is', 'diagnosed', 'with', 'diabetes', 'mellitus', 'due', 'to', 'a', 'plasma', 'blood', 'glucose', 'of', '322', 'mg/dL', 'and', 'a', 'glycosylated', 'hemoglobin', 'of', '9.8%.'], ['His', 'physician', 'gave', 'him', 'dietary', 'recommendations,', 'the', 'convenience', 'of', 'physical', 'exercise,', 'and', 'he', 'started', 'treatment', 'with', 'metformin', '850', 'mg/12', 'hours', 'and', 'glimepiride', '6', 'mg/day.'], ['In', 'the', 'following', 'weeks', 'the', 'glycemic', 'controls', 'are', 'progressively', 'reduced.'], ['At', '4', 'months', 'glycemia', 'is', '94', 'mg/dL', 'and', 'HbA1c', 'is', '5.9%.'], ['The', 'patient', 'complains', 'of', 'frequent', 'episodes', 'of', 'dizziness,', 'epigastric', 'pain,', 'blurred', 'vision,', 'sweating', 'and', 'tremor,', 'which', 'improve', 'with', 'food', 'and', 'occur', 'mainly', 'in', 'the', 'late', 'morning', 'and', 'late', 'afternoon.'], ['What', 'modification', 'would', 'you', 'propose', 'in', 'his', 'treatment?'], ['1-', 'Review', 'dietary', 'carbohydrate', 'distribution.'], ['2-', 'Discontinue', 'metformin.'], ['3-', 'Discontinue', 'sulfonylurea.'], ['4-', 'Substitute', 'metformin', 'with', 'a', 'DPP4', 'inhibitor.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['Discontinue', 'sulfonylurea', 'because', 'of', 'Risk', 'of', 'hypoglycemia.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
223_62
[['QUESTION', 'TYPE:', 'CARDIOLOGY'], ['CLINICAL', 'CASE:'], ['In', 'a', '60-year-old', 'diabetic', 'patient', 'with', 'stable', 'angina', 'secondary', 'to', 'ischemic', 'heart', 'disease', 'due', 'to', 'subtotal', 'obstruction', 'in', 'the', 'middle', 'third', 'of', 'the', 'anterior', 'descending', 'coronary', 'artery,', 'what', 'treatment', 'would', 'you', 'propose?'], ['1-', 'Medical', 'with', 'vasodilators', 'and', 'beta-blockers', 'to', 'avoid', 'angina.'], ['2-', 'Expectorant', 'with', 'rigorous', 'rest,', 'since', 'decreasing', 'myocardial', 'oxygen', 'demand', 'should', 'decrease', 'angina.'], ['3-', 'Surgical', 'revascularization', 'of', 'the', 'ischemic', 'myocardium', 'by', 'means', 'of', 'a', 'left', 'mammary', 'artery', 'bypass', 'distal', 'to', 'the', 'lesion', 'in', 'the', 'diseased', 'coronary', 'artery.'], ['4-', 'Dilatation', 'of', 'the', 'coronary', 'artery', 'lesion', 'by', 'therapeutic', 'catheterization.'], ['5-', 'Therapeutic', 'catheterization', 'to', 'dilate', 'the', 'lesion', 'of', 'the', 'diseased', 'artery', 'and', 'implantation', 'of', 'a', 'stent', 'in', 'the', 'dilated', 'area.'], ['CORRECT', 'ANSWER:', '5'], ['Stable', 'angina', 'in', 'diabetics:', 'this', 'question', 'is', 'a', 'nod', 'to', 'the', 'BARI-2D', 'study', '(NEJM', '2009),', 'which', 'showed', 'that', 'medical', 'management', 'was', 'not', 'inferior', 'to', 'revascularization', '(in', 'fact,', 'the', 'new', 'guidelines', 'reflect', 'the', 'trend', 'that', 'not', 'all', 'coronary', 'stenosis', 'should', 'be', 'systematically', 'opened).'], ['Answer', '1', 'is', 'along', 'these', 'lines,', 'although', 'I', 'miss', 'statins,', 'ACE', 'inhibitors', 'and', 'antiplatelet', 'agents,', 'and', 'I', 'have', 'too', 'many', 'vasodilators', '(nitrates', 'are', 'class', 'IIb,', 'if', 'my', 'memory', 'serves', 'me', 'correctly).'], ['2', 'is', 'absurd:', 'sitting', 'down', 'to', 'avoid', 'angina?'], ["That's", 'like', 'cutting', 'down', 'the', 'forest', 'to', 'prevent', 'fires.'], ['3', 'to', '5', 'are', 'about', 'revascularization:', 'since', 'it', 'is', 'a', 'single', 'vessel', 'and', 'not', 'a', 'proximal', 'LAD,', 'revascularization', 'would', 'have', 'to', 'be', 'percutaneous,', 'so', 'we', 'discard', '3.'], ['Between', '4', 'and', '5,', 'the', 'fifth', 'is', 'more', 'complete:', 'not', 'only', 'would', 'it', 'be', 'necessary', 'to', 'dilate,', 'but', 'also', 'to', 'implant', 'a', 'stent.'], ['So', 'the', 'doubt', 'would', 'be', 'between', '1', 'and', '5.'], ['Applying', 'the', 'general', 'rules', 'of', 'response', 'in', 'the', 'MIR,', 'if', 'two', 'options', 'are', 'similar', 'except', 'in', 'one', 'detail,', 'the', 'correct', 'one', 'is', 'one', 'of', 'these,', 'so', 'we', 'would', 'mark', '5', '(and', 'this', 'is', 'what', 'would', 'be', 'done', 'in', 'any', 'hospital', 'nowadays:', 'a', 'suboccluded', 'artery', 'is', 'dilated', 'directly).'], ['On', 'the', 'other', 'hand,', 'and', 'although', '1', 'is', 'incomplete,', 'I', 'suppose', 'the', 'author', 'wanted', 'to', 'be', 'clever', 'and', 'show', 'that', 'he', 'has', 'read', 'the', 'latest', 'articles.'], ['Conclusion:', 'I', 'would', 'mark', '5...', 'but', 'I', 'would', 'not', 'be', 'surprised', 'if', 'it', 'was', '1.']]
[['O', 'O', 'O'], ['O', 'O'], ['O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
468_122
[['QUESTION', 'TYPE:', 'ORTHOPEDIC', 'SURGERY', 'AND', 'TRAUMATOLOGY'], ['CLINICAL', 'CASE:'], ['A', '70-year-old', 'man', 'consults', 'for', 'non-radiating', 'lumbar', 'pain', 'of', '1', "week's", 'duration,', 'of', 'progressive', 'intensity,', 'accompanied', 'by', 'marked', 'limitation', 'of', 'spinal', 'mobility', 'and', 'febrile', 'fever.'], ['The', 'lumbar', 'spine', 'X-ray', 'shows', 'no', 'alterations.'], ['What', 'diagnosis', 'should', 'we', 'rule', 'out', 'first', 'and', 'with', 'what', 'technique?'], ['1-', 'Vertebral', 'crush', 'with', 'computed', 'tomography', '(CT).'], ['2-', 'Bone', 'metastases', 'with', 'technetium', 'bone', 'scan.'], ['3-', 'Vertebral', 'ankylosing', 'hyperostosis', 'with', 'dorsolumbar', 'spine', 'x-ray.'], ['4-', 'Pyogenic', 'spondylodiscitis', 'with', 'magnetic', 'resonance', 'imaging', '(MRI).'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['We', 'suspect', 'spondylodiscitis', '-', 'the', 'febrile', 'fever', 'and', 'the', 'limitation', 'of', 'mobility', 'of', 'the', 'spine', 'with', 'the', 'acute', 'course', 'give', 'the', 'key', '-,', 'and', 'the', 'indicated', 'test', 'is', 'the', 'MRI.'], ['"The', 'most', 'demonstrative', 'test', 'is', 'magnetic', 'resonance', 'imaging', '(MRI),', 'which', 'is', 'positive', 'even', 'in', 'the', 'first', '2', 'weeks', 'of', 'the', 'picture,', 'which', 'facilitates', 'early', 'diagnosis,', 'with', 'a', 'sensitivity', 'of', '90%".'], ['Vertebral', 'crushing', 'would', 'be', 'seen', 'in', 'the', 'simple', 'X-ray,', 'as', 'well', 'as', 'vertebral', 'ankylosing', 'hyperostosis', 'and', 'many', 'metastases.'], ['In', 'addition,', 'there', 'is', 'no', 'data', 'in', 'the', 'history', 'pointing', 'to', 'bone', 'metastases', '(oncologic', 'history,', 'weight', 'loss', 'etc).']]
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96_170
[['QUESTION', 'TYPE:', 'DERMATOLOGY,', 'VENEREOLOGY', 'AND', 'PLASTIC', 'SURGERY'], ['CLINICAL', 'CASE:'], ['60-year-old', 'male', 'patient', 'who', 'refers', '10', 'days', 'ago', 'the', 'appearance', 'of', 'blistering', 'lesions', 'on', 'dorsum', 'of', 'hands', 'after', 'sun', 'exposure.'], ['The', 'picture', 'is', 'accompanied', 'by', 'skin', 'fragility.'], ['Histopathologically', 'there', 'is', 'a', 'subepidermal', 'blister', 'with', 'PAS+', 'deposits', 'in', 'and', 'around', 'the', 'superficial', 'dermal', 'vessels.'], ['The', 'most', 'plausible', 'diagnosis', 'is:'], ['1-', 'Familial', 'benign', 'pemphigus.'], ['2-', 'Pemphigoid.'], ['3-', 'Porphyria', 'cutanea', 'tarda.'], ['4-', 'Pemphigus', 'vulgaris.'], ['5-', 'Scalded', 'skin', 'syndrome.'], ['CORRECT', 'ANSWER:', '3'], ['Porphyria', 'cutanea', 'tarda', '(PCT)', 'is', 'the', 'most', 'common', 'porphyria', 'and', 'can', 'present', 'with', 'three', 'major', 'clinical', 'forms:', 'familial,', 'sporadic', 'and', 'toxic.'], ['Clinically,', 'it', 'is', 'characterized', 'by', 'marked', 'skin', 'fragility', 'with', 'the', 'appearance', 'of', 'erosions,', 'vesicles', 'and', 'blisters', 'after', 'minimal', 'trauma.'], ['The', 'most', 'frequent', 'sites', 'are', 'the', 'back', 'of', 'the', 'hands', 'and', 'the', 'face,', 'i.e.', 'the', 'areas', 'of', 'greatest', 'photoexposure.'], ['Clinically,', 'the', 'most', 'important', 'differential', 'diagnosis', 'should', 'be', 'established', 'with', 'pseudoporphyria', 'or', 'phototoxic', 'bullous', 'dermatitis,', 'in', 'which', 'the', 'blisters', 'and', 'cutaneous', 'erosions', 'are', 'produced', 'by', 'photosensitivity,', 'induced', 'by', 'drugs', 'such', 'as', 'tetracyclines,', 'sulfonamides,', 'etc.'], ['However,', 'unlike', 'porphyria,', 'porphyrin', 'levels', 'in', 'serum,', 'feces', 'and', 'urine', 'are', 'normal.'], ['The', 'histopathological', 'differential', 'diagnosis', 'should', 'be', 'established', 'with', 'those', 'diseases', 'showing', 'dermal', 'hyaline', 'deposits,', 'such', 'as:', 'hyalinosis', 'cutis,', 'in', 'which', 'unlike', 'porphyria,', 'PAS-positive', 'hyaline', 'deposits', 'are', 'extensive', 'and', 'massively', 'occupy', 'the', 'deep', 'dermis', 'and', 'subcutaneous', 'cellular', 'tissue;', 'Milium', 'colloid', 'in', 'which', 'hyaline', 'material,', 'usually', 'PAS', 'negative', 'expands', 'the', 'papillary', 'dermis,', 'forming', 'characteristic', 'clefts', 'and', 'fissures;', 'and', 'lipoid', 'proteinosis,', 'in', 'which', 'the', 'material', 'is', 'deposited', 'throughout', 'the', 'dermis,', 'has', 'a', 'distribution', 'not', 'only', 'perivascular', 'but', 'more', 'extensive', 'than', 'in', 'porphyria,', 'and', 'usually', 'affects', 'sweat', 'glands.']]
[['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O']]
603_112
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY'], ['CLINICAL', 'CASE:'], ['A', '61-year-old', 'woman,', 'administrative,', 'with', 'a', 'history', 'of', 'overweight,', 'hypertension,', 'dyslipidemia', 'and', 'metabolic', 'syndrome,', 'who', 'consults', 'for', 'pain', 'in', 'both', 'buttocks,', 'left', 'trochanteric', 'region,', 'lateral', 'aspect', 'of', 'the', 'left', 'thigh', 'up', 'to', 'the', 'knee', 'and', 'left', 'leg', 'up', 'to', 'the', 'middle', 'third.'], ['The', 'pain', 'appears', 'when', 'the', 'lower', 'limb', 'is', 'lifted', 'with', 'the', 'knee', 'extended,', 'but', 'is', 'relieved', 'when', 'the', 'knee', 'is', 'flexed.'], ['What', 'is', 'the', 'first', 'clinical', 'suspicion?'], ['1-', 'Gouty', 'arthritis', 'of', 'the', 'left', 'hip.'], ['2-', 'Left', 'coxofemoral', 'arthrosis.'], ['3-', 'Radiated', 'low', 'back', 'pain', '/', 'lumbosciatica.'], ['4-', 'Claudication', 'due', 'to', 'canal', 'stenosis.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['The', 'most', 'common', 'symptomatology', 'of', 'a', 'patient', 'with', 'coxarthrosis', 'includes:', 'hip', 'pain', 'that', 'limits', 'ambulation,', 'nocturnal', 'discomfort', 'and', 'even', 'at', 'rest,', 'hip', 'stiffness', 'and', 'locking.'], ['Coxo-femoral', 'osteoarthrosis', 'presents', 'with', 'a', 'negative', 'Lasegue', 'test.'], ['Wrong', 'answer', '2.'], ['Low', 'back', 'pain', 'of', 'a', 'neuropathic', 'nature', 'usually', 'presents', 'with', 'unilateral', 'and', 'distributed', 'radiculopathy', 'according', 'to', 'dermatomes.'], ['The', 'recognized', 'risk', 'factors', 'are', 'most', 'frequently:', 'women,', 'obesity,', 'smoking', 'and', 'sedentary', 'lifestyle', 'or', 'situations', 'of', 'prolonged', 'sitting.'], ['The', 'lumbosciatica', 'is', 'usually', 'referred', 'to', 'the', 'buttock,', 'posterior', 'aspect', 'of', 'the', 'thighs', 'and', 'even', 'inguinal.'], ['The', 'clinical', 'case', 'describes', 'the', 'Lasegue', 'maneuver', 'or', 'test;', 'a', 'provocation', 'test', 'that', 'evidences', 'radicular', 'irritation', 'in', 'the', 'lumbosacral', 'region', '(Answer', '3', 'correct).'], ['Claudication', 'due', 'to', 'canal', 'stenosis', 'typically', 'presents', 'with', 'pain', 'that', 'worsens', 'with', 'trunk', 'extension', '(walking,', 'standing)', 'and', 'is', 'relieved', 'with', 'flexion', '(sitting,', 'sleeping', 'in', 'the', 'fetal', 'position...)', 'Wrong', 'answer', '4.']]
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574_100
[['QUESTION', 'TYPE:', 'NEUROLOGY'], ['CLINICAL', 'CASE:'], ['An', '80-year-old', 'woman', 'with', 'a', 'history', 'of', 'arterial', 'hypertension', 'and', 'diabetes', 'mellitus', 'who', 'suddenly', 'presents', 'with', 'language', 'impairment.'], ['On', 'arrival', 'at', 'the', 'hospital,', 'an', 'unknown', 'atrial', 'fibrillation', 'is', 'observed,', 'and', 'on', 'examination', 'she', 'presents', 'fluent', 'speech', 'with', 'a', 'tendency', 'to', 'slurred', 'speech,', 'poor', 'language', 'comprehension,', 'inability', 'to', 'repeat', 'and', 'dysnomia.'], ['Semiologically', 'she', 'presents', 'a', 'picture', 'compatible', 'with:'], ['1-', "Broca's", 'aphasia.'], ['2-', 'Conduction', 'aphasia.'], ['3-', 'Sensitive', 'transcortical', 'aphasia.'], ['4-', "Wernicke's", 'aphasia.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['It', 'is', 'a', 'semiology', 'question', 'that', 'helps', 'us', 'to', 'remember', 'the', 'types', 'of', 'aphasia.'], ['The', 'following', 'aspects', 'should', 'be', 'taken', 'into', 'account:', 'language', 'emission', '(fluent,', 'non-fluent,', 'non-emission),', 'comprehension', '(yes', 'or', 'no),', 'repetition', '(yes', 'or', 'no)', 'and', 'nomination.'], ["Wernicke's", 'aphasia', 'or', 'sensitive', 'aphasia', 'has', 'a', 'fluent', 'language,', 'does', 'not', 'understand,', 'does', 'not', 'repeat', 'and', 'does', 'not', 'nominate,', 'just', 'like', 'the', 'patient', 'in', 'the', 'question.'], ['Sensory', 'transcortical', 'aphasia', 'differs', 'from', 'sensory', 'aphasia', 'in', 'that', 'patients', 'are', 'able', 'to', 'repeat.'], ['Conduction', 'aphasia', 'differs', 'from', 'sensory', 'aphasia', 'in', 'that', 'comprehension', 'is', 'preserved,', 'all', 'else', 'being', 'equal.'], ['Finally,', 'in', "broca's", 'aphasia', 'the', 'language', 'is', 'non-fluent,', 'comprehension', 'is', 'preserved,', 'it', 'does', 'not', 'repeat', 'and', 'does', 'not', 'nominate.']]
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67_111
[['QUESTION', 'TYPE:', 'ANESTHESIOLOGY,', 'CRITICAL', 'CARE', 'AND', 'EMERGENCY', 'MEDICINE'], ['CLINICAL', 'CASE:'], ['A', '45-year-old', 'male', 'patient', 'with', 'a', 'history', 'of', 'uric', 'lithiasis', 'and', 'repeated', 'expulsive', 'nephritic', 'colic', 'for', 'the', 'past', '25', 'years', 'comes', 'to', 'the', 'emergency', 'room', 'reporting', 'palpitations', 'and', 'severe', 'right', 'lumbar', 'pain', 'for', 'the', 'past', '2', 'hours.'], ['Urinalysis', 'shows', 'a', 'pH', 'of', '5.5', 'and', 'leukocyturia', 'without', 'proteinuria.'], ['The', 'electrocardiogram', 'confirms', 'a', 'previously', 'unknown', 'AF.'], ['Blood', 'biochemistry', 'shows', 'a', 'Creat', 'of', '0.9,', 'Ca', 'of', '11', 'and', 'LDH', 'of', '950.'], ['What', 'is', 'the', 'most', 'useful', 'diagnostic', 'maneuver', 'to', 'perform?'], ['1-', 'Plain', 'abdominal', 'x-ray.'], ['2-', 'Intravenous', 'urography.'], ['3-', 'Spiral', 'CT', 'with', 'contrast.'], ['4-', 'Abdominal', 'ultrasound.'], ['5-', 'Doppler', 'ultrasound.'], ['CORRECT', 'ANSWER:', '3'], ['In', 'principle,', 'what', 'you', 'tell', 'us', 'does', 'not', 'fit', 'with', 'a', 'nephritic', 'colic.'], ['The', 'urine', 'is', 'normal', '(without', 'hematuria,', 'caused', 'by', 'the', 'lithiasis', 'as', 'it', 'progresses),', 'the', 'Creat', 'is', 'normal', '(it', 'can', 'rise', 'up', 'to', '1.9', 'in', 'nephritic', 'colic).'], ['The', 'increase', 'in', 'LDH', 'is', 'non-specific', 'and', 'can', 'be', 'found', 'in', 'hepatic', 'parenchymal', 'lesions,', 'AMI', 'or', 'pulmonary', 'embolism,', 'as', 'well', 'as', 'in', 'many', 'other', 'less', 'frequent', 'cases', '(tumors,', 'myopathies,', 'etc.).'], ['In', 'this', 'case,', 'we', 'have', 'an', 'important', 'risk', 'factor', 'for', 'embolism,', 'which', 'is', 'atrial', 'fibrillation,', 'which,', 'in', 'addition,', 'being', 'a', '45-year-old', 'male,', 'with', 'no', 'previous', 'history,', 'does', 'not', 'seem', 'to', 'respond', 'to', 'an', 'underlying', 'structural', 'heart', 'disease', 'together', 'with', 'right', 'lumbar', 'pain,', 'which', 'could', 'correspond', 'to', 'irritation', 'of', 'the', 'pleura', 'at', 'the', 'level', 'of', 'the', 'right', 'lumbar', 'spine.'], ['Spiral', 'CT', 'with', 'contrast', 'has', 'acquired', 'great', 'value', 'in', 'the', 'diagnosis', 'of', 'PTE,', 'due', 'to', 'its', 'rapidity', 'and', 'good', 'sensitivity,', 'higher', 'than', '83-92%', 'in', 'most', 'studies,', 'and', 'according', 'to', 'some', 'it', 'can', 'reach', '100%', 'for', 'central', 'thrombi,', 'located', 'in', 'main,', 'lobar', 'or', 'segmental', 'pulmonary', 'arteries.'], ['Its', 'specificity', 'is', 'greater', 'than', '90%.'], ['Nodes', 'can', 'produce', 'false', 'positives.'], ['It', 'can', 'also', 'provide', 'an', 'alternative', 'diagnosis', 'in', 'case', 'PTE', 'is', 'not', 'confirmed,', 'so', 'it', 'would', 'be', 'a', 'very', 'useful', 'test.'], ['Doppler', 'ultrasound', 'would', 'be', 'the', 'most', 'useful', 'test', 'to', 'diagnose', 'the', 'source', 'of', 'the', 'emboli,', 'so', 'it', 'could', 'also', 'be', 'a', 'valid', 'answer', 'depending', 'on', 'what', 'they', 'mean', 'by', '"useful".'], ['It', 'is', 'a', 'noninvasive', 'technique', 'that', 'has', 'demonstrated', 'its', 'good', 'sensitivity', 'and', 'specificity', 'in', 'the', 'diagnosis', 'of', 'DVT', 'compared', 'to', 'phlebography.'], ['It', 'also', 'allows', 'the', 'diagnosis', 'of', 'other', 'pathologies', 'that', 'could', 'justify', 'the', "patient's", 'symptoms.'], ['Its', 'limitations', 'are', 'the', 'assessment', 'of', 'infrapopliteal', 'thrombi', 'and,', 'in', 'many', 'cases,', 'in', 'patients', 'who', 'are', 'not', 'thin,', 'of', 'the', 'iliac', 'and', 'cava', 'veins.']]
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77_31
[['QUESTION', 'TYPE:', 'DIGESTIVE', 'SYSTEM'], ['CLINICAL', 'CASE:'], ['A', '17-year-old', 'boy', 'with', "Crohn's", 'disease', 'with', 'colonic', 'involvement', 'of', '2', 'years', 'of', 'evolution,', 'in', 'maintenance', 'treatment', 'with', 'azathioprine,', 'consults', 'for', 'the', 'appearance', 'since', '5', 'days', 'ago', 'of', 'purplish-red,', 'hot,', 'painful,', 'bilateral', 'subcutaneous', 'nodules', 'of', 'pretibial', 'location,', 'associated', 'with', 'an', 'increase', 'in', 'the', 'number', 'of', 'stools', 'and', 'abdominal', 'pain.'], ['The', 'most', 'appropriate', 'approach', 'in', 'this', 'case', 'is:'], ['1-', 'Recommend', 'relative', 'rest', 'and', 'warm', 'cloths', 'on', 'both', 'legs', 'and', 'add', 'antidepressant', 'treatment.'], ['2-', 'Biopsy', 'skin', 'areas', 'away', 'from', 'the', 'injured', 'areas', 'and', 'prescribe', 'opioid', 'analgesics', 'at', 'the', 'beginning.'], ['3-', 'Biopsy', 'skin', 'areas', 'away', 'from', 'the', 'injured', 'areas', 'and', 'prescribe', 'opioid', 'analgesics', 'at', 'the', 'beginning.'], ['4-', 'Suspect', 'bilateral', 'lower', 'extremity', 'ischemia', 'of', 'drug', 'origin.'], ['5-', 'Adjustment', 'of', 'the', 'treatment', 'of', 'the', 'disease.'], ['CORRECT', 'ANSWER:', '5'], ['It', 'appears', 'that', 'the', 'patient', 'has', 'erythema', 'nodosum', 'lesions', 'associated', 'with', 'a', 'flare', 'of', 'his', 'disease,', 'which', 'is', 'common.'], ['Treatment', 'of', 'the', 'disease', 'and', 'its', 'control', 'usually', 'improves', 'the', 'cutaneous', 'lesions.'], ['The', 'lesions', 'should', 'not', 'be', 'biopsied.']]
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440_97
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203_47
[['QUESTION', 'TYPE:', 'GENERAL', 'SURGERY'], ['CLINICAL', 'CASE:'], ['55-year-old', 'woman,', 'operated', 'on', 'for', 'appendicitis', '24', 'years', 'ago,', 'who', 'comes', 'in', 'because', 'while', 'previously', 'well,', 'she', 'has', 'started', 'with', 'repeated', 'vomiting', 'after', 'breakfast,', 'about', '12', 'hours', 'ago,', 'associated', 'with', 'abdominal', 'distention.'], ['She', 'presented', 'a', 'diarrhea', 'stool', 'a', 'few', 'hours', 'after', 'the', 'onset', 'of', 'the', 'symptoms.'], ['Examination', 'revealed', 'abdominal', 'distension,', 'tympanism', 'and', 'increased', 'bowel', 'sounds,', 'but', 'no', 'peritoneal', 'irritation.'], ['Laboratory', 'tests', 'showed', 'no', 'abnormalities.'], ['The', 'abdominal', 'X-ray', 'showed', 'dilatation', 'of', 'the', 'small', 'bowel', 'loops,', 'without', 'gas', 'in', 'the', 'rectal', 'ampulla.'], ['Regarding', 'this', 'case', 'it', 'is', 'true', 'that:'], ['1-', 'This', 'is', 'a', 'picture', 'of', 'intestinal', 'flange', 'obstruction', 'requiring', 'emergency', 'laparotomy.'], ['2-', 'Most', 'likely', 'we', 'are', 'facing', 'a', 'case', 'of', 'obstruction', 'at', 'the', 'level', 'of', 'the', 'large', 'intestine.'], ['3-', 'The', 'fact', 'that', 'the', 'patient', 'presented', 'a', 'diarrheal', 'stool', 'allows', 'us', 'to', 'exclude', 'the', 'diagnosis', 'of', 'intestinal', 'obstruction.', 'Further', 'imaging', 'studies', 'are', 'necessary', 'to', 'ensure', 'a', 'diagnosis.'], ['4-', 'We', 'should', 'indicate', 'the', 'practice', 'of', 'a', 'decompressive', 'colonoscopy.'], ['5-', 'Initial', 'management', 'should', 'be', 'conservative,', 'with', 'serum', 'therapy,', 'nasogastric', 'aspiration', 'and', 'periodic', 'clinical,', 'analytical', 'and', 'radiographic', 'monitoring.'], ['CORRECT', 'ANSWER:', '5'], ['This', 'is', 'a', 'typical', 'description', 'of', 'a', 'picture', 'of', 'intestinal', 'obstruction', 'due', 'to', 'bridging', 'or', 'adhesions', 'due', 'to', 'previous', 'surgery.'], ['The', 'correct', 'answer', 'is', '5', 'and', 'not', '1', 'because', 'most', 'of', 'these', 'situations', 'resolve', 'spontaneously', 'with', 'conservative', 'treatment.']]
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158_133
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY', 'AND', 'ORTHOPEDICS'], ['CLINICAL', 'CASE:'], ['Obese', '12-year-old', 'boy', '(87', 'kg).'], ['He', 'has', 'been', 'complaining', 'of', 'mechanical', 'pain', 'in', 'the', 'right', 'thigh', 'and', 'knee', 'for', '4', 'months.'], ['Clinical', 'examination', 'reveals', 'a', '1', 'cm', 'discrepancy', 'in', 'the', 'length', 'of', 'the', 'lower', 'extremities', 'and', 'an', 'attitude', 'of', 'the', 'right', 'lower', 'extremity', 'in', 'external', 'rotation', 'with', 'loss', 'of', 'internal', 'rotation.'], ['We', 'should', 'suspect', 'that', 'he', 'presents:'], ['1-', 'Juvenile', 'chronic', 'arthritis.'], ['2-', 'Epiphysiolysis', 'capitis', 'femoris.'], ['3-', 'Fracture', 'of', 'the', 'femoral', 'neck', 'due', 'to', 'overload.'], ['4-', 'Perthes', 'disease.'], ['5-', 'Sequelae', 'of', 'developmental', 'dysplasia', 'of', 'the', 'hip.'], ['CORRECT', 'ANSWER:', '2'], ['We', 'are', 'presented', 'with', 'an', 'adolescent', 'patient', 'who', 'is', 'overweight', 'with', 'pain', 'in', 'the', 'thigh', 'and', 'knee,', 'a', 'length', 'discrepancy', 'of', '1', 'cm', 'and', 'the', 'limb', 'in', 'external', 'rotation.'], ['This', 'picture', 'should', 'automatically', 'lead', 'us', 'to', 'mark', 'epiphysiolysis', 'capitis', 'femoris', '(proximal', 'femoral', 'epiphysiolysis,', 'the', 'fact', 'of', 'reading', 'it', 'in', 'Latin', 'nomina', 'is', 'a', 'bit', 'of', 'a', 'misunderstanding', 'but', 'it', 'should', 'not', 'mislead', 'us).'], ['We', 'should', 'think', 'of', 'this', 'one', 'because', 'it', 'is', 'the', 'most', 'frequent', 'and', 'possible', '(correct', 'answer', '2).'], ['The', 'other', 'options', 'are', 'not', 'impossible', 'but', 'they', 'are', 'less', 'frequent', 'and', 'they', 'would', 'not', 'ask', 'us', 'this', 'if', 'they', 'wanted', 'us', 'to', 'choose', 'another', 'option.'], ['If', 'they', 'were', 'sequelae', 'of', 'hip', 'dysplasia,', 'it', 'would', 'not', 'have', 'this', '4-month', 'onset', 'and', 'the', 'age', 'of', 'onset', 'would', 'be', 'earlier.'], ['Complications', 'of', 'dysplasia', 'are', 'dislocations', 'and', 'subluxations', 'that', 'may', 'require', 'surgery', 'and', 'avascular', 'necrosis', 'of', 'the', 'head', '(false', 'answer', '5).'], ['Perthes', 'disease', 'occurs', 'in', 'younger', 'children', '(4-9', 'years)', 'with', 'episodes', 'of', 'limping', 'and', 'pain', 'in', 'the', 'hip', 'and', 'knee', '(false', 'answer', '4).'], ['In', 'a', 'child', 'the', 'most', 'typical', 'would', 'be', 'a', 'fracture', 'at', 'the', 'level', 'of', 'the', 'physis,', 'not', 'at', 'the', 'level', 'of', 'the', 'femoral', 'neck,', 'so', 'we', 'discard', '3.'], ['For', 'us', 'to', 'consider', 'this', 'option', 'we', 'would', 'have', 'to', 'have', 'been', 'presented', 'with', 'a', 'bone', 'cyst,', 'something', 'that', 'would', 'justify', 'a', 'weakness', 'in', 'the', 'femoral', 'neck', 'area.'], ['As', 'for', 'juvenile', 'chronic', 'arthritis,', 'it', 'is', 'a', 'rheumatoid', 'option', 'surrounded', 'by', 'trauma', 'options.'], ['They', 'do', 'not', 'speak', 'to', 'us', 'of', 'rheumatologic', 'factors', 'in', 'an', 'analytical', 'analysis,', 'nor', 'of', 'a', 'polyarticular', 'picture.'], ['Perhaps', 'we', 'could', 'think', 'about', 'this', 'one', 'because', 'they', 'talk', 'about', 'pain', 'in', 'the', 'right', 'knee,', 'but', 'this', 'picture', 'that', 'they', 'present', 'us', 'is', 'limited', 'to', 'the', 'right', 'lower', 'limb,', 'they', 'do', 'not', 'talk', 'about', 'other', 'joints', 'or', 'fever', 'or', 'other', 'accompanying', 'systemic', 'symptoms,', 'so', 'it', 'is', 'not', 'an', 'option', 'to', 'evaluate,', 'especially', 'with', 'the', 'other', 'options', 'presented', 'to', 'us', 'that', 'would', 'be', 'more', 'likely', 'in', 'view', 'of', 'the', 'picture', 'presented', 'to', 'us', '(option', '1', 'false).'], ['In', 'addition,', 'the', 'knee', 'pain', 'in', 'this', 'case', 'refers', 'to', 'a', 'referred', 'pain', 'of', 'the', 'hip,', 'without', 'involvement', 'of', 'the', 'knee.']]
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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
46_155
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['A', '1-year-old', 'boy', 'whose', 'mother', 'has', 'just', 'been', 'diagnosed', 'with', 'bacilliferous', 'pulmonary', 'tuberculosis,', 'having', 'started', 'correct', 'treatment.'], ['The', 'child', 'is', 'asymptomatic', 'with', 'a', 'normal', 'examination,', 'negative', 'tuberculin', 'test', '(PT)', 'and', 'normal', 'chest', 'Rx.'], ['What', 'would', 'be', 'the', 'attitude', 'to', 'adopt', 'in', 'the', 'child?'], ['1-', 'Only', 'separate', 'him', 'from', 'the', 'mother', 'until', 'her', 'treatment', 'is', 'completed', '(at', 'least', '6', 'months).'], ['2-', 'Perform', 'a', 'high-resolution', 'CT', 'scan', 'of', 'the', 'lung,', 'and', 'if', 'normal,', 'repeat', 'PT', 'at', '8-12', 'weeks.'], ['3-', 'Chemoprophylaxis', 'with', 'isoniazid', '(INH)', 'until', 'the', "mother's", 'smear', 'test', 'is', 'negative.'], ['4-', 'Chemoprophylaxis', 'with', 'INH', '6-9', 'months.', 'New', 'PT', 'and', 'chest', 'X-ray', 'at', 'the', 'end', 'of', 'treatment,', 'to', 'decide', 'whether', 'or', 'not', 'to', 'conclude', 'treatment.'], ['5-', 'Chemoprophylaxis', 'with', 'INH,', '8-12', 'weeks.', 'Repeat', 'PT.', 'If', 'negative,', 'stop', 'treatment.', 'If', 'positive,', 'perform', 'chest', 'X-ray', 'to', 'decide', 'whether', 'or', 'not', 'there', 'is', 'disease.'], ['CORRECT', 'ANSWER:', '5'], ['The', 'correct', 'answer', 'is', '5.'], ['The', 'mother', 'should', 'be', 'isolated', 'for', 'the', 'first', '2-4', 'weeks', 'of', 'treatment,', 'after', 'which', 'she', 'would', 'no', 'longer', 'be', 'contagious.'], ['If', 'the', 'result', 'of', 'the', 'repeat', 'PT', 'is', 'still', 'negative,', 'the', 'child', 'should', 'not', 'be', 'tested', 'again.'], ['If', 'it', 'is', 'positive,', 'the', 'X-ray', '(or', 'pulmonary', 'CT', 'in', 'younger', 'children)', 'should', 'be', 'repeated.']]
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593_146
null
null
395_136
null
null
424_91
[['QUESTION', 'TYPE:', 'ENDOCRINOLOGY'], ['CLINICAL', 'CASE:'], ['A', '27-year-old', 'woman', 'consults', 'for', 'secondary', 'amenorrhea', 'of', 'one', 'year', 'of', 'evolution.'], ['She', 'has', 'no', 'iatrogenic', 'history.'], ['Analytically,', 'the', 'estradiol', 'concentration', 'is', 'below', 'normal', 'and', 'the', 'prolactin', 'value', 'is', '12', 'ng/mL.'], ['Indicate', 'which', 'of', 'the', 'following', 'examinations', 'would', 'you', 'request', 'as', 'a', 'first', 'step', 'to', 'try', 'to', 'identify', 'the', 'origin', 'of', 'the', 'disorder:'], ['1-', 'Hypothalamohypophyseal', 'MRI.'], ['2-', 'Karyotype.'], ['3-', 'Basal', 'FSH.'], ['4-', 'Chorionic', 'gonadotropin', 'stimulation.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['Young', 'woman', 'with', 'secondary', 'amenorrhea,', 'with', 'no', 'history', 'of', 'interest.'], ['Prolactin', 'values', 'are', 'normal', '(values', 'above', '20ngr/ml', 'are', 'considered', 'hyperprolectinemia),', 'thus', 'ruling', 'out', 'hyperprolactinemia', 'as', 'the', 'cause', 'of', 'amenorrhea.'], ['They', 'tell', 'us', 'that', 'the', 'estrogen', 'level', 'is', 'low.'], ['In', 'this', 'case', 'we', 'should', 'suspect', 'early', 'ovarian', 'failure.'], ['For', 'its', 'diagnosis', 'we', 'will', 'ask', 'for', 'a', 'basal', 'FSH', '(in', 'cases', 'of', 'premature', 'ovarian', 'failure', 'it', 'would', 'be', 'elevated).']]
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169_87
[['QUESTION', 'TYPE:', 'CARDIOLOGY', 'AND', 'CARDIOVASCULAR', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '70-year-old', 'woman,', 'hypertensive', 'and', 'diabetic,', 'who', 'has', 'worked', 'as', 'a', 'sales', 'clerk', 'all', 'her', 'life.'], ['She', 'consults', 'for', 'an', 'internal', 'malleolar', 'lesion', 'in', 'the', 'right', 'leg', 'with', 'intense', 'pain', 'throughout', 'the', 'day', 'that', 'worsens', 'at', 'night.'], ['On', 'examination,', 'there', 'are', 'uncomplicated', 'varicose', 'cords', 'in', 'both', 'extremities', 'and', 'normal', 'femoral', 'and', 'popliteal', 'pulses', 'with', 'absence', 'of', 'distal', 'pulses.'], ['What', 'examination', 'should', 'we', 'perform', 'first?'], ['1-', 'Venous', 'echo-Doppler', 'of', 'lower', 'limbs.'], ['2-', 'Angioresonance', 'of', 'lower', 'limbs.'], ['3-', 'Arteriography.'], ['4-', 'Ankle-brachial', 'index.'], ['5-', 'AngioCT.'], ['CORRECT', 'ANSWER:', '4'], ['At', 'least', 'for', 'me,', 'as', 'a', 'family', 'physician,', 'I', 'usually', 'start', 'with', 'the', 'least', 'invasive', 'and', 'most', 'cost-effective', 'tests,', 'and', 'in', 'the', 'case', 'described,', 'an', 'ischemic', 'problem', 'in', 'the', 'lower', 'limbs', 'is', 'the', 'ankle-brachial', 'index.']]
[['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
95_170
[['QUESTION', 'TYPE:', 'DERMATOLOGY,', 'VENEREOLOGY', 'AND', 'PLASTIC', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '60-year-old', 'male', 'patient', 'who', 'reported', '10', 'days', 'ago', 'the', 'appearance', 'of', 'blistering', 'lesions', 'on', 'the', 'dorsum', 'of', 'the', 'hands', 'after', 'sun', 'exposure.'], ['The', 'picture', 'is', 'accompanied', 'by', 'skin', 'fragility.'], ['Histopathologically', 'there', 'is', 'a', 'subepidermal', 'blister', 'with', 'PAS+', 'deposits', 'in', 'and', 'around', 'the', 'superficial', 'dermal', 'vessels.'], ['The', 'most', 'plausible', 'diagnosis', 'is:'], ['1-', 'Familial', 'benign', 'pemphigus.'], ['2-', 'Pemphigoid.'], ['3-', 'Porphyria', 'cutanea', 'tarda.'], ['4-', 'Pemphigus', 'vulgaris.'], ['5-', 'Scalded', 'skin', 'syndrome.'], ['CORRECT', 'ANSWER:', '3'], ['The', 'fact', 'of', 'being', 'a', 'photoinduced', 'picture,', 'the', 'histology', 'and', 'the', 'age', 'make', 'the', 'diagnosis', 'of', 'PCT', 'more', 'probable', '(3).'], ['The', 'rest', 'of', 'the', 'answers', 'do', 'not', 'fit', 'with', 'the', 'clinical', 'picture', 'or', 'the', 'histology.']]
[['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
537_1
null
null
363_97
[['QUESTION', 'TYPE:', 'HEMATOLOGY'], ['CLINICAL', 'CASE:'], ['A', '35-year-old', 'patient', 'who,', 'due', 'to', 'hematemesis', 'due', 'to', 'ulcus,', 'receives', 'a', 'transfusion', 'of', '2', 'packed', 'red', 'blood', 'cells.'], ['5-10', 'minutes', 'after', 'starting', 'the', 'transfusion,', 'she', 'begins', 'with', 'fever,', 'chills,', 'hypotension', 'and', 'pain', 'in', 'the', 'lumbar', 'region.'], ['What', 'would', 'be', 'the', 'most', 'likely', 'diagnosis?'], ['1-', 'Bacterial', 'contamination', 'of', 'the', 'blood.'], ['2-', 'Febrile', 'reaction', 'secondary', 'to', 'transfusion.'], ['3-', 'Febrile', 'reaction', 'due', 'to', 'plasma', 'contaminating', 'red', 'blood', 'cells.'], ['4-', 'Hemolytic', 'transfusion', 'reaction.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['Acute', 'hemolytic', 'transfusion', 'reactions', 'can', 'occur', 'within', 'minutes.'], ['Clinically', 'they', 'are', 'characterized', 'by', 'chills,', 'fever,', 'urticaria,', 'tachycardia,', 'nausea', 'and', 'vomiting,', 'lumbar', 'pain,', 'hemorrhage', 'due', 'to', 'disseminated', 'intravascular', 'coagulation', '(DIC).....'], ['We', 'are', 'told', 'of', 'a', 'patient', 'who,', 'within', 'minutes', 'of', 'starting', 'a', 'transfusion,', 'presented', 'with', 'an', 'acute', 'and', 'very', 'serious', 'condition', '(with', 'shock).'], ['Such', 'an', 'acute', 'and', 'severe', 'situation', 'only', 'fits', 'option', '4.']]
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339_33
[['QUESTION', 'TYPE:', 'GYNECOLOGY', 'AND', 'OBSTETRICS'], ['CLINICAL', 'CASE:'], ['67-year-old', 'woman', 'diagnosed', 'with', 'an', 'infiltrating', 'ductal', 'carcinoma', 'of', 'the', 'breast', 'and', 'no', 'family', 'history', 'of', 'neoplasia.'], ['What', 'additional', 'studies', 'should', 'be', 'performed', 'on', 'the', 'tumor', 'for', 'its', 'clinical-therapeutic', 'implications?'], ['1-', 'Complete', 'phenotypic', 'study', 'by', 'flow', 'cytometry.'], ['2-', 'Study', 'of', 'hormone', 'receptors', 'and', 'HER2.'], ['3-', 'Study', 'of', 'hormone', 'receptors,', 'e-cadherin', 'and', 'study', 'of', 'first-degree', 'relatives.'], ['4-', 'BRCA', '1-2', 'study', 'and', 'study', 'of', 'first-degree', 'relatives.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['All', 'breast', 'carcinomas', 'should', 'be', 'accompanied', 'by', 'the', 'study', 'of', 'hormone', 'receptors', 'and', 'HER-2', 'for', 'the', 'prognostic', 'implications', 'of', 'the', 'tumor,', 'as', 'well', 'as', 'the', 'adequacy', 'of', 'the', 'treatment', 'of', 'the', 'same,', 'since', 'depending', 'on', 'the', 'result', 'will', 'apply', 'some', 'drugs', 'or', 'others.'], ['The', 'study', 'of', 'relatives', 'and', 'the', 'BCRA', 'gene', 'is', 'not', 'indicated', 'since', 'she', 'does', 'not', 'have', 'a', 'family', 'history', 'of', 'neoplasia.']]
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144_142
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['A', '13-year-old', 'girl', 'consults', 'us', 'for', 'weight', 'loss,', 'asthenia,', 'secondary', 'amenorrhea', 'and', 'constipation.'], ['Examination', 'revealed', 'a', 'temperature', 'of', '35ºC,', 'weight', 'below', 'the', '3rd', 'percentile,', 'bradycardia', 'and', 'orthostatic', 'hypotension.'], ['Laboratory', 'tests', 'showed', 'anemia', 'with', 'mild', 'leukopenia,', 'cholesterol', 'of', '230', 'mg/dL', 'and', 'on', 'the', 'electrocardiogram', 'a', 'flattened', 'T', 'wave', 'with', 'ST-segment', 'elevation', 'and', 'prolonged', 'QTc.'], ['What', 'process', 'would', 'you', 'suspect', 'and', 'what', 'would', 'you', 'do', 'next?'], ['1-', 'Suspect', 'anorexia', 'nervosa', 'and', 'inquire', 'about', 'intake,', 'body', 'image,', 'etc.'], ['2-', 'Suspect', 'hypothyroidism', 'and', 'request', 'TSH', 'and', 'thyroid', 'hormones.'], ['3-', 'Suspect', 'cardiomyopathy', 'and', 'request', 'echocardiography.'], ['4-', 'I', 'would', 'suspect', 'celiac', 'disease', 'and', 'request', 'anti-transglutaminase', 'IgA', 'antibodies.'], ['5-', 'Suspect', 'panhypopituitarism', 'and', 'request', 'a', 'cranial', 'CT', 'scan.'], ['CORRECT', 'ANSWER:', '1'], ['The', 'correct', 'answer', 'is', '1.'], ['The', 'symptoms', 'and', 'signs', 'described', 'are', 'the', 'biological', 'findings', 'associated', 'with', 'anorexia', 'nervosa.'], ['The', 'ECG', 'disturbances', 'are', 'derived', 'from', 'electrolyte', 'disturbances.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
356_166
[['QUESTION', 'TYPE:', 'GYNECOLOGY', 'AND', 'OBSTETRICS'], ['CLINICAL', 'CASE:'], ['A', 'pregnant', 'woman,', '10', 'weeks', 'pregnant,', 'comes', 'to', 'the', 'emergency', 'room', 'with', 'a', 'blood', 'pressure', 'of', '160/105', 'mmHg.'], ['She', 'is', 'in', 'good', 'general', 'condition,', 'with', 'only', 'mild', 'headache,', 'which', 'is', 'the', 'reason', 'for', 'taking', 'her', 'blood', 'pressure.'], ['After', '4', 'hours', 'of', 'rest', 'she', 'presented', 'with', 'a', 'blood', 'pressure', 'of', '150/95mmHg.'], ['A', 'complete', 'blood', 'count', 'is', 'normal', 'and', 'proteinuria', 'is', 'negative.'], ['What', 'type', 'of', 'hypertension', 'does', 'she', 'have?'], ['1-', 'Moderate', 'pre-eclampsia.'], ['2-', 'Pregnancy-induced', 'hypertension.'], ['3-', 'Chronic', 'hypertension.'], ['4-', 'Eclampsia.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['Chronic', 'hypertension.'], ['This', 'is', 'hypertension', 'that', 'is', 'detected', 'before', 'pregnancy', 'or', 'before', 'the', '20th', 'week', 'of', 'pregnancy', 'and/or', 'persists', 'at', '12', 'weeks', 'postpartum.']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
495_64
[['QUESTION', 'TYPE:', 'MEDICAL', 'ONCOLOGY'], ['CLINICAL', 'CASE:'], ['65-year-old', 'woman', 'with', 'no', 'comorbidities,', 'undergoing', 'left', 'breast-conserving', 'surgery', 'with', 'selective', 'sentinel', 'lymph', 'node', 'biopsy.'], ['The', 'pathological', 'anatomy', 'of', 'the', 'specimen', 'shows', 'an', 'infiltrating', 'ductal', 'carcinoma', 'grade', 'III', 'of', '11', 'mm,', 'two', 'negative', 'sentinel', 'nodes,', 'estrogen', 'receptors:', '0%,', 'progesterone', 'receptors:', '0%,', 'Ki', '67:', '70%,', 'HER2:', 'negative.'], ['The', 'extension', 'study', 'is', 'negative.'], ['Adjuvant', 'treatment', 'would', 'be:'], ['1-', 'Chemotherapy', 'based', 'on', 'anthracyclines', 'and', 'taxanes,', 'radiotherapy', 'and', 'trastuzumab.'], ['2-', 'Chemotherapy', 'based', 'on', 'anthracyclines', 'and', 'taxanes,', 'radiotherapy', 'and', 'tamoxifen.'], ['3-', 'Chemotherapy', 'based', 'on', 'anthracyclines', 'and', 'taxanes,', 'and', 'radiotherapy.'], ['4-', 'Chemotherapy', 'based', 'on', 'anthracyclines', 'and', 'taxanes,', 'radiotherapy', 'and', 'aromatase', 'inhibitors,', 'since', 'it', 'is', 'postmenopausal.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['Typical', 'question,', 'conservative', 'surgery', 'implies', 'radiate,', 'for', 'sure.'], ['High', 'grade,', 'and', 'no', 'hormone', 'receptors', 'or', 'her2', '(the', 'dreaded', 'triple', 'negative).'], ['I', 'was', 'there', 'when', 'there', 'were', 'no', 'taxanes', 'or', 'herceptin', 'and', 'I', 'was', 'in', 'the', 'trials', 'that', 'showed', 'that', 'more', 'and', 'more', 'are', 'being', 'cured,', 'unfortunately', 'still', 'not', 'all.'], ['That', 'is', 'why', 'today,', 'anthracyclines', '(does', 'not', 'suffer', 'from', 'heart)', 'and', 'taxanes', 'before', 'RT.'], ['My', 'specialty', 'is', 'beautiful,', 'and', 'will', 'be', 'more', 'so', 'in', 'the', 'coming', 'years.']]
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355_166
[['QUESTION', 'TYPE:', 'GYNECOLOGY', 'AND', 'OBSTETRICS'], ['CLINICAL', 'CASE:'], ['A', 'pregnant', 'woman,', '10', 'weeks', 'pregnant,', 'comes', 'to', 'the', 'emergency', 'room', 'with', 'a', 'blood', 'pressure', 'of', '160/105', 'mmHg.'], ['She', 'is', 'in', 'good', 'general', 'condition,', 'with', 'only', 'mild', 'headache,', 'which', 'is', 'the', 'reason', 'for', 'taking', 'her', 'blood', 'pressure.'], ['After', '4', 'hours', 'of', 'rest', 'she', 'presented', 'with', 'a', 'blood', 'pressure', 'of', '150/95mmHg.'], ['A', 'complete', 'blood', 'count', 'is', 'normal', 'and', 'proteinuria', 'is', 'negative.'], ['What', 'type', 'of', 'hypertension', 'is', 'present?'], ['1-', 'Moderate', 'preeclampsia.'], ['2-', 'Pregnancy-induced', 'hypertension.'], ['3-', 'Chronic', 'hypertension.'], ['4-', 'Eclampsia.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['The', 'correct', 'answer', 'is', '3.'], ['The', 'SEGO', 'in', 'its', '2006', 'protocol', '"Hypertensive', 'disorders', 'of', 'pregnancy"', 'refers', 'that', 'this', 'is', 'chronic', 'hypertension,', 'although', 'diagnosed', 'in', 'pregnancy.'], ['This', 'is', 'because', 'it', 'has', 'been', 'diagnosed', 'at', '10', 'weeks', 'of', 'gestation.'], ['Above', '20', "weeks'", 'gestation,', 'we', 'would', 'be', 'talking', 'about', 'preeclampsia', '(if', 'HT', '+', 'proteinuria', 'or', 'uterine', 'artery', 'pulsatility', 'index', 'above', 'the', '95th', 'percentile),', 'pregnancy-induced', 'hypertension', '(only', 'HT)', 'or', 'eclampsia', '(a', 'form', 'of', 'severe', 'preeclampsia).']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
94_31
[['QUESTION', 'TYPE:', 'DERMATOLOGY,', 'VENEREOLOGY', 'AND', 'PLASTIC', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '17-year-old', 'boy', 'with', "Crohn's", 'disease', 'with', 'colonic', 'involvement', 'of', '2', 'years', 'of', 'evolution,', 'in', 'maintenance', 'treatment', 'with', 'azathioprine,', 'consults', 'for', 'the', 'appearance', 'for', '5', 'days', 'of', 'subcutaneous', 'red', 'purplish,', 'hot,', 'painful,', 'bilateral,', 'pretibial', 'localization', 'nodules,', 'associated', 'with', 'an', 'increase', 'in', 'the', 'number', 'of', 'stools', 'and', 'abdominal', 'pain.'], ['The', 'most', 'appropriate', 'approach', 'in', 'this', 'case', 'is:'], ['1-', 'Recommend', 'relative', 'rest', 'and', 'warm', 'cloths', 'on', 'both', 'legs', 'and', 'add', 'antidepressant', 'treatment.'], ['2-', 'Biopsy', 'areas', 'of', 'skin', 'away', 'from', 'the', 'injured', 'areas', 'and', 'prescribe', 'opioid', 'analgesics', 'for', 'entry.'], ['3-', 'Suspect', 'the', 'existence', 'of', 'a', 'malignant', 'intestinal', 'tumor', 'lesion', 'as', 'a', 'trigger', 'of', 'the', 'cutaneous', 'process.'], ['4-', 'Suspect', 'bilateral', 'lower', 'extremity', 'ischemia', 'of', 'drug-induced', 'origin.'], ['5-', 'Adjustment', 'of', 'bowel', 'disease', 'treatment.'], ['CORRECT', 'ANSWER:', '5'], ['The', "patient's", 'presenting', 'picture', 'is', 'presumably', 'erythema', 'nodosum.'], ['About', '10%', 'of', 'cases', 'of', 'erythema', 'nodosum', 'are', 'associated', 'with', 'inflammatory', 'bowel', 'disease,', 'both', 'ulcerative', 'colitis', 'and', "Crohn's", 'disease.'], ['As', 'mentioned,', 'in', 'most', 'cases,', 'erythema', 'nodosum', 'has', 'a', 'self-limited', 'course.'], ['When', 'associated', 'with', 'inflammatory', 'bowel', 'disease,', 'erythema', 'nodosum', 'usually', 'resolves', 'with', 'treatment', 'of', 'the', 'intestinal', 'flare,', 'and', 'recurs', 'with', 'disease', 'recurrences.'], ['Local', 'measures', 'include', 'elevation', 'of', 'the', 'legs', 'and', 'bed', 'rest.'], ['In', 'particularly', 'severe', 'cases,', 'oral', 'administration', 'of', 'potassium', 'iodide', 'has', 'been', 'shown', 'to', 'be', 'helpful.'], ['Although', 'the', 'use', 'of', 'aspirin', 'and', 'other', 'NSAIDs', 'is', 'effective', 'for', 'erythema', 'nodosum,', 'their', 'use', 'in', 'patients', 'with', 'inflammatory', 'bowel', 'disease', 'should', 'be', 'limited,', 'as', 'they', 'may', 'worsen', 'the', 'intestinal', 'picture,', 'the', 'usefulness', 'of', 'antidepressants', 'in', 'this', 'picture', 'has', 'not', 'been', 'described,', 'so', 'answer', 'nº1', 'would', 'not', 'be', 'correct.']]
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39_134
[['QUESTION', 'TYPE:', 'OTORHINOLARYNGOLOGY', 'AND', 'MAXILLOFACIAL', 'SURGERY'], ['CLINICAL', 'CASE:'], ['60-year-old', 'woman,', 'diagnosed', 'with', 'breast', 'cancer', 'treated', 'with', 'surgery', 'and', 'radiotherapy', '10', 'years', 'ago.'], ['Currently', 'with', 'metastases', 'in', 'the', 'dorsal', 'spine', 'and', 'sacroiliac', 'joint,', 'for', 'which', 'she', 'has', 'received', 'monthly', 'treatment', 'with', 'i.v.', 'zoledronic', 'acid', 'for', 'the', 'last', 'two', 'years.'], ['The', 'patient', 'presented', 'spontaneous', 'bone', 'exposure', 'at', 'the', 'level', 'of', 'the', 'mandibular', 'bone', 'of', 'approximately', '2', 'cm.'], ['There', 'are', 'no', 'signs', 'of', 'acute', 'infection', 'and', 'the', 'gum', 'around', 'the', 'bone', 'exposure', 'is', 'strictly', 'normal.'], ['The', 'mandibular', 'CT', 'scan', 'shows', 'an', 'area', 'of', 'bone', 'sclerosis.'], ['What', 'would', 'be', 'the', 'diagnosis?'], ['1-', 'Odontogenic', 'abscess.'], ['2-', 'Osteonecrosis', 'due', 'to', 'bisphosphonates.'], ['3-', 'Osteoradionecrosis.'], ['4-', 'Dental', 'root', 'included.'], ['5-', 'Metastasis', 'of', 'breast', 'carcinoma.'], ['CORRECT', 'ANSWER:', '2'], ['This', 'one', 'has', 'been', 'difficult', 'for', 'me,', 'we', 'are', 'going', 'to', 'rule', 'it', 'out.'], ['1', 'cannot', 'be,', 'because', 'there', 'would', 'be', 'infectious', 'signs.'], ['Answer', '2', 'is', 'possible', 'because', 'bisphosphonates', 'create', 'mandibular', 'necrosis.'], ['3', 'seems', 'unlikely', 'to', 'me', 'because', 'the', 'radiotherapy', 'that', 'the', 'patient', 'received', 'would', 'be', 'oriented', 'on', 'the', 'breast', 'and', 'not', 'on', 'the', 'mandible.'], ['I', 'rule', 'out', 'number', '4,', 'as', 'it', 'is', 'not', 'a', 'case', 'of', 'dental', 'root', 'involvement.'], ['5', 'is', 'possible;', 'after', 'all,', 'the', 'patient', 'already', 'has', 'bone', 'metastases.'], ['So,', 'I', 'hesitate', 'between', '2', 'and', '5,', 'which', 'one', 'to', 'choose?'], ['I', 'am', 'certainly', 'not', 'sure', 'what', 'a', 'bone', 'sclerosis', 'means', 'on', 'a', 'CT', 'scan,', 'but', 'a', 'bone', 'metastasis', 'would', 'be', 'more', 'destructive', 'than', 'sclerotizing.'], ['On', 'the', 'other', 'hand,', 'using', 'reverse', 'psychology,', 'what', 'did', 'the', 'questioner', 'want', 'me', 'to', 'know?'], ['That', 'bisphosphonates', 'can', 'create', 'mandibular', 'necrosis?'], ['Or', 'that', 'a', 'woman', 'with', 'several', 'bone', 'metastases', 'can', 'have', 'a', 'metastasis', 'also', 'in', 'the', 'mandible?'], ['The', 'latter', 'seems', 'too', 'simple,', 'and', 'would', 'make', 'me', 'lean', 'more', 'towards', '2,', 'but', "it's", 'not', 'clear', 'to', 'me.'], ['Be', 'that', 'as', 'it', 'may,', 'between', 'two', 'possible', 'answers', 'you', 'have', 'to', 'always', 'answer,', 'and', 'between', '2', 'and', '5,', 'you', 'have', 'to', 'check', '2,', 'which', 'is', 'more', 'likely.']]
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252_83
[['QUESTION', 'TYPE:', 'DIGESTIVE', 'SYSTEM'], ['CLINICAL', 'CASE:'], ['What', 'disease', 'would', 'we', 'suspect', 'in', 'a', 'young', 'patient', 'with', 'a', 'frequent', 'history', 'of', 'dysphagia', 'to', 'solids', 'and', 'liquids', 'with', 'repeated', 'food', 'impactions,', 'without', 'symptoms', 'of', 'heartburn', 'and', 'in', 'whom', 'oral', 'endoscopy', 'shows', 'multiple', 'concentric', 'esophageal', 'rings', 'with', 'normal', 'mucosa', '(trachealized', 'appearance)?'], ['1-', 'Herpetic', 'esophagitis.'], ['2-', 'Eosinophilic', 'esophagitis.'], ['3-', 'Candidiasis', 'esophagitis.'], ['4-', 'Cytomegalovirus', 'esophagitis.'], ['5-', 'Adenocarcinoma', 'of', 'the', 'esophagus.'], ['CORRECT', 'ANSWER:', '2'], ['The', 'endoscopic', 'appearance', 'of', 'trachealized', 'esophagus', 'is', 'very', 'typical', 'of', 'eosinophilic', 'esophagitis,', 'which', 'presents', 'with', 'dysphagia', 'and', 'repeated', 'food', 'impactions.']]
[['O', 'O', 'O', 'O'], ['O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
57_77
[['QUESTION', 'TYPE:', 'ENDOCRINOLOGY'], ['CLINICAL', 'CASE:'], ['In', 'a', '42-year-old', 'obese', 'woman,', 'cortisol', 'levels', 'in', 'blood,', 'urine', 'and', 'saliva', 'are', 'determined', 'and', 'in', 'all', 'the', 'determinations', 'they', 'are', 'elevated.'], ['After', 'performing', 'the', 'nocturnal', 'suppression', 'test', 'with', 'dexamethasone,', 'cortisol', 'levels', 'in', 'blood', 'remain', 'elevated,', 'so', 'ACTH', 'independent', "Cushing's", 'syndrome', 'is', 'suspected,', 'what', 'additional', 'test', 'would', 'you', 'request', 'to', 'confirm', 'the', 'diagnosis', 'at', 'this', 'time?'], ['1-', 'A', 'petrosal', 'sinus', 'catheterization.'], ['2-', 'A', 'gammagraphy', 'with', 'labeled', 'somatostatin', '(Octreoscan).'], ['3-', 'A', 'scan', 'with', 'Sesta-MIBI.'], ['4-', 'An', 'abdominal', 'ultrasound.'], ['5-', 'An', 'adrenal', 'CT', 'scan.'], ['CORRECT', 'ANSWER:', '5'], ['Anyway,', 'I', 'think', 'that', 'the', 'clinical', 'case', 'is', 'poorly', 'stated,', 'since', 'before', 'doing', 'the', 'CT', 'scan,', 'ACTH', 'should', 'be', 'measured', 'and,', 'once', 'ACTH', 'is', 'suppressed,', 'the', 'CT', 'scan', 'should', 'be', 'done.'], ['But', 'since', 'the', 'question', 'is', '"what', 'would', 'you', 'do', 'to', 'confirm', 'the', 'diagnosis', 'of', 'suspected', 'ACTH', 'independent', "Cushing's", 'syndrome",', 'the', 'answer', 'is', 'CT.']]
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595_88
null
null
98_171
[['QUESTION', 'TYPE:', 'DERMATOLOGY,', 'VENEREOLOGY', 'AND', 'PLASTIC', 'SURGERY'], ['CLINICAL', 'CASE:'], ['The', 'patient', 'presents', 'since', '2', 'weeks', 'ago', 'a', 'pruritic', 'eruption', 'consisting', 'of', 'multiple', 'polygonal', 'erythematous-violaceous', 'papules,', 'with', 'flattened', 'surface,', 'preferentially', 'located', 'on', 'the', 'anterior', 'aspect', 'of', 'the', 'wrists,', 'pretibial', 'area', 'and', 'lumbar', 'area.'], ['She', 'also', 'presents', 'whitish', 'reticulated', 'lesions', 'in', 'the', 'jugal', 'mucosa.'], ['What', 'is', 'the', 'most', 'probable', 'diagnosis?'], ['1-', 'Pityriasis', 'versicolor.'], ['2-', 'Mycosis', 'fungoides.'], ['3-', 'Psoriasis', 'in', 'drops.'], ['4-', 'Pityriasis', 'rosea', 'of', 'Gibert.'], ['5-', 'Lichen', 'planus.'], ['CORRECT', 'ANSWER:', '5'], ['Lichen', 'planus', 'is', 'a', 'very', 'common', 'dermatosis', 'of', 'unknown', 'etiology', 'characterized', 'by', 'the', 'appearance', 'of', 'pruritic', 'polygonal', 'papules,', 'with', 'a', 'purplish', 'color', 'and', 'shiny', 'surface,', 'preferentially', 'located', 'in', 'the', 'distal', 'areas', 'of', 'the', 'extremities.'], ['Characteristically', 'these', 'papules', 'show', 'a', 'symmetrical', 'distribution', 'and', 'are', 'preferentially', 'located', 'on', 'the', 'anterior', 'aspect', 'of', 'the', 'wrists', '(Figure', '1)', 'and', 'ankles.'], ['Oral', 'mucosal', 'involvement', 'is', 'very', 'frequent,', 'and', 'approximately', '75%', 'of', 'patients', 'with', 'lichen', 'planus', 'show', 'an', 'asymptomatic', 'whitish', 'reticulation', 'affecting', 'the', 'jugal', 'or', 'lingual', 'mucosa.']]
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118_117
[['QUESTION', 'TYPE:', 'INFECTOLOGY'], ['CLINICAL', 'CASE:'], ['A', '14-year-old', 'asymptomatic', 'boy', 'whose', 'father', 'has', 'just', 'been', 'diagnosed', 'with', 'pulmonary', 'TB', 'undergoes', 'a', 'Mantoux', 'test,', 'with', 'a', 'negative', 'result.'], ['What', 'is', 'the', 'appropriate', 'course', 'of', 'action?'], ['1-', 'Reassure', 'her', 'that', 'she', 'is', 'not', 'at', 'risk.'], ['2-', 'Chest', 'X-ray.'], ['3-', 'Start', 'chemoprophylaxis', 'and', 'repeat', 'skin', 'test', 'after', '3', 'months.'], ['4-', 'Repeat', 'skin', 'test', 'at', 'one', 'month.'], ['5-', 'A', 'sputum', 'study', 'should', 'be', 'performed', 'before', 'starting', 'chemoprophylaxis', 'with', 'Isoniazid', 'for', '1', 'year.'], ['CORRECT', 'ANSWER:', '3'], ['In', 'young', 'contacts,', 'chemoprophylaxis', 'should', 'be', 'started', 'even', 'if', 'the', 'mantoux', 'test', 'is', 'negative', 'and', 'repeated', 'after', '2-3', 'months', 'to', 'decide', 'whether', 'to', 'continue', 'treatment', 'for', '6', 'months', '(if', 'it', 'turns', 'positive)', 'or', 'to', 'stop', 'it.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
388_233
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421_78
[['QUESTION', 'TYPE:', 'GENERAL', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', '52-year-old', 'man', 'was', 'referred', 'to', 'the', 'gastroenterology', 'department', 'for', 'hematochezia,', 'tenesmus', 'and', 'reduction', 'of', 'stool', 'diameter.'], ['A', 'series', 'of', 'tests', 'were', 'performed', 'and', 'a', 'diagnosis', 'of', 'adenocarcinoma', 'of', 'the', 'sigma', 'without', 'distant', 'metastasis', 'was', 'made.'], ['The', 'patient', 'underwent', 'surgery', 'and', 'was', 'referred', 'to', 'the', 'medical', 'oncology', 'department', 'for', 'evaluation', 'of', 'complementary', 'chemotherapy', 'treatment.'], ['Which', 'of', 'the', 'following', 'is', 'a', 'poor', 'prognostic', 'factor', 'after', 'surgical', 'resection', 'and', 'should', 'be', 'taken', 'into', 'account', 'when', 'planning', 'chemotherapy', 'treatment?'], ['1-', 'The', 'presence', 'of', 'anemia', 'at', 'diagnosis.'], ['2-', 'The', 'existence', 'of', 'a', 'family', 'history', 'of', 'colorectal', 'cancer.'], ['3-', 'The', 'size', 'of', 'the', 'primary', 'lesion', 'and', 'histological', 'differentiation.'], ['4-', 'Perforation', 'or', 'adhesion', 'of', 'the', 'tumor', 'to', 'adjacent', 'organs.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['On', 'this', 'occasion,', 'we', 'are', 'asked', 'about', 'which', 'factors', 'have', 'the', 'greatest', 'influence', 'in', 'order', 'to', 'carry', 'out', 'adjuvant', 'chemotherapy', 'in', 'colorectal', 'cancer.'], ['In', 'order', 'to', 'do', 'so,', 'we', 'must', 'know', 'which', 'are', 'the', 'poor', 'prognostic', 'factors', 'in', 'this', 'pathology', 'where', 'obstruction', 'or', 'intestinal', 'perforation', 'due', 'to', 'the', 'lesion,', 'invasion', 'of', 'adjacent', 'organs,', 'elevation', 'of', 'tumor', 'markers', 'such', 'as', 'CEA', 'and', 'the', 'histology', 'of', 'the', 'neoplasm', 'stand', 'out.'], ['Among', 'these,', 'less', 'importance', 'is', 'given', 'to', 'the', 'size', 'of', 'the', 'lesion', 'than', 'to', 'its', 'degree', 'of', 'invasion', 'of', 'the', 'intestinal', 'wall', 'or', 'other', 'adjacent', 'structures,', 'a', 'criterion', 'that', 'must', 'be', 'taken', 'into', 'account', 'for', 'staging', 'by', 'TNM', 'or', 'Astler-Coller', 'classification,', 'which', 'guide', 'the', 'indication', 'of', 'adjuvant', 'treatment', 'after', 'the', 'surgical', 'approach.']]
[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O', 'O', 'O', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
500_45
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['15-year-old', 'female', 'presenting', 'with', 'delayed', 'menarche', 'and', 'short', 'stature.'], ['She', 'does', 'not', 'have', 'intellectual', 'disability.'], ['Which', 'of', 'the', 'following', 'genetic', 'tests', 'would', 'be', 'routinely', 'used', 'for', 'the', 'diagnosis', 'of', 'this', 'patient:'], ['1-', 'Massive', 'sequencing', '(NGS).'], ['2-', 'FISH.'], ['3-', 'DNA', 'and/or', 'RNA', 'microarrays.'], ['4-', 'Karyotype.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['In', 'a', 'woman', 'with', 'delayed', 'puberty', 'and', 'short', 'stature', 'we', 'should', 'always', 'think', 'about', 'and', 'rule', 'out', 'Turner', 'syndrome,', 'whose', 'diagnosis', 'is', 'made', 'by', 'karyotyping', '(45X0).']]
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611_116
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY'], ['CLINICAL', 'CASE:'], ['95-year-old', 'woman', 'living', 'in', 'a', 'nursing', 'home,', 'independent', 'for', 'her', 'basic', 'activities', 'of', 'daily', 'living,', 'goes', 'out', 'to', 'the', 'garden', 'for', 'walks.'], ['She', 'has', 'a', 'history', 'of', 'hypertension,', 'dyslipidemia,', 'osteoporosis', 'and', 'mild', 'cognitive', 'impairment.'], ['She', 'suffers', 'a', 'fall', 'when', 'getting', 'up', 'at', 'night', 'to', 'go', 'to', 'the', 'bathroom.'], ['X-ray', 'shows', 'a', 'displaced', 'subcapital', 'fracture', 'of', 'the', 'right', 'hip.'], ['What', 'is', 'the', 'recommended', 'treatment?'], ['1-', 'Hip', 'hemiarthroplasty.'], ['2-', 'Trochanteric', 'nail', 'fixation.'], ['3-', 'Fixation', 'with', 'cannulated', 'screws.'], ['4-', 'Conservative:', 'bed-chair', 'life.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['We', 'are', 'told', 'of', 'a', 'case', 'of', 'a', '95-year-old', 'patient', 'with', 'a', 'displaced', 'intracapsular', '(subcapital)', 'hip', 'fracture.'], ['In', 'this', 'case,', 'the', 'surgical', 'options', 'may', 'be', 'the', 'use', 'of', 'cannulated', 'screws', 'or', 'hip', 'arthroplasty.'], ['Cannulated', 'screws', 'are', 'reserved', 'for', 'cases', 'of', 'non-displaced', 'fractures', '(Wrong', 'answer', '2)', 'so', 'the', 'most', 'indicated', 'option', 'would', 'be', 'arthroplasty,', 'in', 'this', 'case', 'hemiarthroplasty', '(Correct', 'answer', '1).'], ['Trochanteric', 'pins', 'are', 'reserved', 'for', 'extracapsular', 'fractures', '(Wrong', 'answer', '2)', 'and', 'conservative', 'treatment', 'is', 'only', 'considered', 'in', 'patients', 'with', 'very', 'low', 'functional', 'demand', 'or', 'surgical', 'contraindication', '(Wrong', 'answer', '4).']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim']]
542_38
[['QUESTION', 'TYPE:', 'ALLERGOLOGY'], ['CLINICAL', 'CASE:'], ['A', '25-year-old', 'woman', 'with', 'a', 'history', 'of', 'allergic', 'bronchial', 'asthma', 'due', 'to', 'sensitization', 'to', 'grass', 'pollens', 'and', 'atopic', 'dermatitis.'], ['She', 'suddenly', 'presents', 'hypotension,', 'tachycardia,', 'urticaria', 'and', 'bronchospasm', 'after', 'ingesting', 'peanuts', 'and', 'is', 'transferred', 'to', 'the', 'emergency', 'department.'], ['What', 'would', 'be', 'the', 'order', 'of', 'drugs', 'to', 'be', 'administered', 'and', 'what', 'laboratory', 'test', 'could', 'be', 'requested', 'for', 'further', 'evaluation?'], ['1-', 'Intramuscular', 'adrenaline,', 'followed', 'by', 'an', 'inhaled', 'bronchodilator', 'of', 'the', 'SABA', 'type', 'and', 'intramuscular', 'dexchlorpheniramine.', 'Then', 'request', 'serum', 'tryptase.'], ['2-', 'An', 'inhaled', 'SABA-type', 'bronchodilator,', 'followed', 'by', 'intramuscular', 'dexchlorpheniramine', 'and', 'intramuscular', 'adrenaline.', 'Then', 'order', 'serum', 'tryptase.'], ['3-', 'Intramuscular', 'dexchlorpheniramine,', 'followed', 'by', 'an', 'inhaled', 'bronchodilator', 'of', 'the', 'SABA', 'type', 'and', 'intramuscular', 'adrenaline.', 'Then', 'request', 'eosinophil', 'cationic', 'protein.'], ['4-', 'Intramuscular', 'adrenaline,', 'followed', 'by', 'an', 'inhaled', 'bronchodilator', 'of', 'the', 'SABA', 'type', 'and', 'intramuscular', 'dexchlorpheniramine.', 'Then', 'request', 'eosinophil', 'cationic', 'protein.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['The', 'patient', 'is', 'suffering', 'from', 'anaphylactic', 'shock', 'secondary', 'to', 'peanut', 'ingestion.'], ['The', 'treatment', 'of', 'anaphylaxis', 'and', 'anaphylactic', 'shock', 'of', 'first', 'choice', 'is', 'intramuscular', 'adrenaline', '1mg/ml', '(dose', '0.01', 'mg/kg,', 'in', 'adults', '0.5', 'mg', 'maximum).'], ['Followed', 'by', 'symptomatic', 'treatment', 'to', 'stabilize', 'the', 'airway', 'with', '100%', 'high', 'flow', 'O2,', 'ensure', 'large', 'caliber', 'venous', 'access,', 'fluid', 'replacement', 'and', 'continuous', 'monitoring', '(HR,', 'BP,', 'SatO2', ',', 'diuresis).'], ['As', 'adjuvant', 'treatment,', 'an', 'inhaled', 'bronchodilator', 'such', 'as', 'SABA,', 'intramuscular', 'dexchlorpheniramine', 'or', 'corticosteroids', 'such', 'as', 'hydrocortisone', 'IV', 'or', 'methylprednisolone', 'IV', 'can', 'be', 'administered.'], ['Adrenaline', 'can', 'be', 'repeated', 'at', 'the', 'same', 'doses', 'every', '5', 'minutes', 'a', 'maximum', 'of', '3', 'times', 'and', 'if', 'after', '15', 'minutes', 'there', 'is', 'no', 'response,', 'IV', 'adrenaline', 'infusion', 'should', 'be', 'started,', 'Glucagon', '(if', 'treatment', 'with', 'beta-blockers),', 'Atropine', '(if', 'prolonged', 'bradycardia)', 'or', 'Vasopressors', '(if', 'refractory', 'hypotension).'], ['The', 'laboratory', 'marker', 'that', 'should', 'be', 'requested', 'if', 'anaphylaxis', 'is', 'suspected', 'is', 'serum', 'tryptase', 'in', 'the', 'first', 'hour', 'for', 'a', 'basal', 'determination', 'and', 'another', 'at', '4-6', 'hours', 'to', 'observe', 'its', 'elevation', 'curve.'], ['It', 'is', 'not', 'an', 'emergency', 'marker', 'but', 'it', 'is', 'very', 'useful', 'for', 'future', 'allergological', 'study.']]
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79_36
[['QUESTION', 'TYPE:', 'DIGESTIVE', 'SYSTEM'], ['CLINICAL', 'CASE:'], ['Which', 'of', 'the', 'following', 'clinical', 'data,', 'recorded', 'during', 'the', 'clinical', 'history', 'taking', 'of', 'a', 'patient', 'with', 'diarrhea', 'of', 'more', 'than', '4', 'weeks', 'of', 'evolution,', 'can', 'be', 'found', 'in', 'people', 'without', 'organic', 'pathology:'], ['1-', 'Weight', 'loss', 'with', 'or', 'without', 'rectorrhagia.'], ['2-', 'Persistence', 'of', 'diarrhea', 'during', 'the', 'night.'], ['3-', 'Onset', 'of', 'symptoms', 'after', 'age', '50.'], ['4-', 'Presence', 'of', 'dermatitis', 'and/or', 'arthritis', 'during', 'the', 'examination.'], ['5-', 'Expulsion', 'of', 'mucus', 'in', 'more', 'than', '25%', 'of', 'defecations.'], ['CORRECT', 'ANSWER:', '5'], ['Although', 'mucus', 'is', 'usually', 'more', 'frightening', 'in', 'the', 'consultation,', 'it', 'falls', 'within', 'the', 'Rome', 'II', 'criteria', 'for', 'the', 'diagnosis', 'of', 'Irritable', 'Bowel', 'Syndrome.'], ['All', 'the', 'rest', 'are', 'typical', 'signs', 'of', 'organicity,', 'although', 'I', 'think', 'the', 'question', 'is', 'poorly', 'phrased,', 'since', 'any', 'of', 'these', 'data', '(especially', 'age)', 'can', 'be', 'found', 'in', 'patients', 'who', 'in', 'the', 'end', 'have', 'nothing,', 'what', 'happens', 'is', 'that', 'in', 'these', 'cases', 'we', 'must', 'always', 'look', 'for', 'organicity.']]
[['O', 'O', 'O', 'O'], ['O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O', 'B-Premise', 'I-Premise', 'I-Premise'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]
524_54
[['QUESTION', 'TYPE:', 'STATISTICS'], ['CLINICAL', 'CASE:'], ['An', '86-year-old', 'woman', 'in', 'whom', 'nonvalvular', 'atrial', 'fibrillation', 'has', 'been', 'detected.'], ['She', 'has', 'a', 'CHADS2', 'score', 'of', '3', 'points.'], ['In', 'the', 'literature,', 'similar', 'patients', 'on', 'warfarin', 'therapy', 'have', 'a', 'stroke', 'risk', 'of', '2.2%', 'vs.', '5.2%', 'in', 'patients', 'without', 'warfarin.'], ['What', 'would', 'be', 'the', 'number', 'needed', 'to', 'treat', '(NNT)', 'to', 'prevent', 'an', 'emboligenic', 'stroke', 'with', 'anticoagulation', 'therapy:'], ['1-', '3'], ['2-', '19,2.'], ['3-', '33,3.'], ['4-', '49,5.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['On', 'average,', 'if', '100', 'patients', 'like', 'this', 'woman', 'are', 'treated', 'with', 'warfarin,', 'the', 'number', 'of', 'strokes', 'is', 'reduced', 'by', '3', '(from', '5.2', 'untreated', 'to', '3.2', 'treated).'], ['Therefore,', 'if', 'you', 'treat', '33.3', 'patients', 'like', 'this', 'woman', 'with', 'warfarin,', 'you', 'reduce', 'the', 'number', 'of', 'strokes', 'by', '1:', 'the', 'NNT', 'is', '33.3.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
319_141
[['QUESTION', 'TYPE:', 'RHEUMATOLOGY'], ['CLINICAL', 'CASE:'], ['A', '20-year-old', 'boy', 'consults', 'for', 'lumbosacral', 'pain', 'of', 'inflammatory', 'rhythm', 'of', '4', 'months', 'of', 'evolution.'], ['Also', 'bilateral', 'thalalgia', 'and', 'morning', 'stiffness', 'for', '1', 'hour.'], ['In', 'the', 'last', '2', 'months,', 'onset', 'of', 'diarrhea', 'with', 'loss', 'of', '4', 'kg', 'of', 'weight.'], ['What', 'is', 'the', 'most', 'correct', 'diagnostic', 'approach?'], ['1-', 'Given', 'the', "patient's", 'age,', 'he', 'most', 'likely', 'suffers', 'from', 'non-specific', 'low', 'back', 'pain', 'and', 'tendonitis', 'in', 'the', 'feet.', 'If', 'the', 'diarrhea', 'persists,', 'a', 'digestive', 'study', 'would', 'be', 'performed.'], ['2-', 'I', 'would', 'perform', 'a', 'digestive', 'study', 'to', 'rule', 'out', 'tumor', 'pathology.', 'The', 'lumbar', 'pain', 'may', 'be', 'due', 'to', 'visceral', 'pathology.'], ['3-', 'The', 'clinical', 'picture', 'is', 'very', 'suggestive', 'of', 'spondyloarthritis.', 'Inflammatory', 'bowel', 'disease', 'should', 'be', 'ruled', 'out.'], ['4-', 'I', 'would', 'request', 'a', 'lumbar', 'MRI', 'to', 'rule', 'out', 'disc', 'herniation', 'and', 'if', 'diarrhea', 'persists,', 'a', 'digestive', 'study.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['The', 'clinical', 'picture', 'is', 'typical', 'of', 'spondyloarthritis,', 'and', 'together', 'with', 'the', 'digestive', 'symptoms', 'it', 'is', 'probably', 'associated', 'with', 'inflammatory', 'bowel', 'disease.']]
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400_147
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY', 'AND', 'ORTHOPEDICS'], ['CLINICAL', 'CASE:'], ['A', '13-year-old', 'boy', 'presents', 'dorsal', 'pain', 'of', 'several', 'months', 'of', 'evolution,', 'only', 'on', 'standing', 'and', 'walking,', 'what', 'diagnosis', 'should', 'we', 'consider?'], ['1-', "Scheuermann's", 'disease.'], ['2-', 'Thoracic', 'scoliosis.'], ['3-', 'Malignant', 'tumor', 'of', 'the', 'vertebral', 'body.'], ['4-', 'It', 'is', 'a', 'mechanical', 'overload.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['The', 'pain', 'is', 'of', 'mechanical', 'characteristics,', 'and', 'the', 'most', 'frequent', 'cause', 'of', 'mechanical', 'back', 'pain', 'in', 'adolescents', 'is', 'mechanical', 'overload.'], ['There', 'is', 'no', 'data', 'in', 'the', 'statement', 'to', 'suggest', 'any', 'of', 'the', 'other', 'etiologies.']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]
196_164
[['QUESTION', 'TYPE:', 'PEDIATRICS'], ['CLINICAL', 'CASE:'], ['A', '4-year-old', 'boy', 'consulted', 'for', 'the', 'appearance', 'over', 'the', 'last', 'three', 'days', 'of', 'skin', 'lesions', 'on', 'the', 'legs', 'and', 'buttocks.'], ['His', 'parents', 'reported', 'that', 'his', 'pediatrician', 'had', 'diagnosed', 'an', 'upper', 'respiratory', 'tract', 'infection', '10', 'days', 'earlier.'], ['In', 'the', 'last', '12', 'hours', 'she', 'presented', 'intense', 'colicky', 'abdominal', 'pain', 'and', 'had', 'two', 'diarrheal', 'stools.'], ['Afebrile.'], ['No', 'weight', 'loss.'], ['On', 'examination', 'she', 'has', 'numerous', 'petechiae', 'and', 'palpable', 'purpuric', 'lesions', 'predominantly', 'on', 'the', 'buttocks', 'and', 'lower', 'extremities.'], ['Good', 'general', 'condition', 'although', 'she', 'has', 'intense', 'abdominal', 'pain.'], ['Abdominal', 'palpation', 'is', 'difficult', 'to', 'assess', 'due', 'to', 'diffuse', 'pain.'], ['No', 'visceromegaly.'], ['No', 'other', 'findings', 'of', 'interest', 'on', 'examination.'], ['Which', 'of', 'the', 'following', 'data', 'does', 'NOT', 'support', 'your', 'diagnostic', 'suspicion?'], ['1-', 'Knee', 'and', 'ankle', 'arthritis.'], ['2-', 'Hematuria.'], ['3-', 'Plateletopenia.'], ['4-', 'Fecal', 'occult', 'blood.'], ['5-', 'Scrotal', 'edema.'], ['CORRECT', 'ANSWER:', '3'], ['You', 'are', 'describing', 'a', 'Schönlein-Henoch', 'purpura', 'which', 'is', 'a', 'vasculitic', 'phenomenon,', 'so', 'the', 'lesions', 'are', 'not', 'due', 'to', 'plateletopenia.'], ['Scrotal', 'edema', '(sometimes', 'even', 'torsion', 'of', "Morgani's", 'capsid', 'of', 'the', 'testis)', 'is', 'not', 'exceptional', 'in', 'males', 'with', 'S.', 'Schönlein-Henoch.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise'], ['B-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
509_150
[['QUESTION', 'TYPE:', 'DIGESTIVE'], ['CLINICAL', 'CASE:'], ['83-year-old', 'male', 'who', 'consults', 'for', 'a', 'recurrent', 'picture', 'of', 'abdominal', 'pain', 'in', 'the', 'left', 'iliac', 'fossa,', 'accompanied', 'by', 'diarrhea', 'of', 'up', 'to', '6', 'stools', 'per', 'day', 'without', 'pathological', 'products,', 'of', '10-15', 'days', 'of', 'evolution.'], ['No', 'fever', 'or', 'general', 'condition', 'was', 'reported.'], ['A', 'recent', 'blood', 'test', 'showed', 'no', 'leukocytosis', 'and', 'a', 'negative', 'fecal', 'occult', 'blood', 'test.'], ['On', 'examination', 'there', 'is', 'mild', 'pain', 'on', 'palpation', 'of', 'the', 'left', 'iliac', 'fossa', 'without', 'peritoneal', 'irritation.'], ['He', 'had', 'a', 'colonoscopy', 'three', 'years', 'ago', 'in', 'which', 'diverticula', 'were', 'reported', 'along', 'the', 'entire', 'colon,', 'more', 'numerous', 'in', 'the', 'left', 'colon,', 'with', 'no', 'other', 'associated', 'lesions.'], ['Which', 'of', 'the', 'following', 'would', 'be', 'the', 'best', 'approach', 'to', 'follow?'], ['1-', 'Empirical', 'treatment', 'with', 'antibiotics.'], ['2-', 'Request', 'a', 'preferential', 'colonoscopy.'], ['3-', 'Request', 'urgent', 'abdominal', 'ultrasound.'], ['4-', 'Refer', 'to', 'surgery', 'to', 'evaluate', 'sigmoidectomy.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['They', 'refer', 'to', 'a', 'concept', 'that', 'has', 'emerged', 'relatively', 'recently', 'and', 'is', 'not', 'present', 'in', 'all', 'clinical', 'guidelines', 'as', 'uncomplicated', 'symptomatic', 'diverticular', 'disease.'], ['In', 'these', 'cases,', 'the', 'therapeutic', 'trial', 'with', 'rifaximin', 'is', 'recommended,', 'being', 'the', 'true', 'number', '1.'], ['The', 'absence', 'of', 'acute', 'phase', 'reactants', 'in', 'the', 'CBC', 'suggests', 'that', 'she', 'does', 'not', 'have', 'acute', 'diverticulitis', 'at', 'the', 'time', 'of', 'consultation', 'that', 'would', 'lead', 'us', 'to', 'request', 'an', 'imaging', 'test', 'to', 'rule', 'it', 'out.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
549_128
null
null
221_48
[['QUESTION', 'TYPE:', 'ANATOMIC', 'PATHOLOGY'], ['CLINICAL', 'CASE:'], ['A', '20-year-old', 'man', 'with', 'ataxia,', 'headaches', 'and', 'solid-cystic', 'mass', 'in', 'the', 'right', 'cerebellar', 'hemisphere', 'underwent', 'surgery', 'and', 'a', 'lesion', 'was', 'resected,', 'histologically', 'showing', 'cells', 'with', 'long', 'thin', 'cytoplasmic', 'processes,', 'fascicular', 'and', 'microcystic', 'pattern,', 'numerous', 'vessels', 'and', "Rosenthal's", 'fibers.'], ['The', 'most', 'probable', 'anatomopathologic', 'diagnosis', 'is:'], ['1-', 'Pilocytic', 'astrocytoma.'], ['2-', 'Pleomorphic', 'xanthoastrocytoma.'], ['3-', 'Central', 'neurocytoma.'], ['4-', 'Liponeurocytoma.'], ['5-', 'Prion', 'disease.'], ['CORRECT', 'ANSWER:', '1'], ['A', 'question', 'that', 'does', 'not', 'seem', 'to', 'have', 'a', 'second', 'intention,', 'as', 'there', 'are', 'no', 'confusing', 'elements.'], ['The', 'statement', 'concisely', 'summarizes', 'the', 'description', 'of', 'pilocytic', 'astrocytoma.'], ['The', 'Rosenthal', 'fibers', 'may', 'confuse', 'us', 'as', 'they', 'are', 'not', 'very', 'specific,', 'and', 'make', 'us', 'think,', 'for', 'example,', 'of', 'pleomorphic', 'xanthoastrocytoma', 'in', 'which', 'they', 'can', 'also', 'be', 'found,', 'but', 'the', 'cell', 'morphology', 'described', '(long', 'and', 'thin', 'cytoplasmic', 'processes,', 'which', 'are', 'the', 'ones', 'that', 'give', 'the', 'name', '"pilocytic")', 'keeps', 'us', 'the', 'first', 'option', 'as', 'the', 'correct', 'one.'], ['We', 'can', 'find', 'a', 'good', 'description', 'of', 'the', 'entity,', 'explaining', 'what', 'distinguishes', 'it', 'from', 'other', 'glial', 'tumors', 'in', 'Practical', 'Surgical', 'Neuropathology.'], ['A', 'Diagnostic', 'Approach.'], ['A.'], ['Perry,', 'D.J.'], ['Brat.'], ['p82-88.'], ['Churchill', 'Livingstone', 'Elsevier.'], ['2010.'], ['(Philadephia).']]
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606_113
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY'], ['CLINICAL', 'CASE:'], ['35-year-old', 'male,', 'letter', 'carrier,', 'with', 'no', 'history', 'of', 'interest,', 'who', 'comes', 'to', 'the', 'emergency', 'department', 'for', 'acute', 'cervical', 'pain', 'of', '24', 'hours', 'of', 'evolution,', 'without', 'previous', 'trauma,', 'which', 'radiates', 'to', 'the', 'left', 'arm', 'up', 'to', 'the', 'hand', 'and', 'is', 'accompanied', 'by', 'paresthesia', 'in', 'the', 'radial', 'border', 'of', 'the', 'forearm.'], ['She', 'presents', 'no', 'objectifiable', 'loss', 'of', 'strength,', 'preserves', 'neck', 'mobility', 'although', 'it', 'is', 'painful', 'and', 'contracture', 'of', 'the', 'paravertebral', 'musculature', 'is', 'appreciated.'], ['The', 'first', 'attitude', 'will', 'be:'], ['1-', 'Conservative', 'treatment', 'with', 'non-steroidal', 'anti-inflammatory', 'drugs,', 'local', 'heat', 'and', 'relative', 'rest.'], ['2-', 'Urgent', 'call', 'to', 'the', 'neurosurgeon', 'for', 'surgical', 'evaluation.'], ['3-', 'Preferential', 'request', 'for', 'MRI', 'and', 'electromyogram.'], ['4-', 'Preferential', 'referral', 'to', 'traumatology', 'outpatients.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['Correct', 'answer', '1.'], ['75%', 'of', 'patients', 'with', 'radiculopathy', 'improve', 'with', 'non-surgical', 'treatment,', 'this', 'being', 'the', 'treatment', 'of', 'choice', 'in', 'the', 'initial', 'stages.'], ['Magnetic', 'resonance', 'imaging', 'is', 'of', 'choice', 'in', 'certain', '"red', 'flags":', 'fever,', 'weight', 'loss,', 'nocturnal', 'pain,', 'persistence', 'of', 'symptoms', 'despite', 'conservative', 'treatment', 'and', 'loss', 'of', 'strength', '(incorrect', 'answer', '3).']]
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436_223
null
null
220_126
null
null
483_174
[['QUESTION', 'TYPE:', 'CRITICAL', 'CARE'], ['CLINICAL', 'CASE:'], ['A', '22-year-old', 'woman', 'presents', 'with', 'sudden', 'cardiac', 'arrest', 'with', 'a', 'rhythm', 'that', 'is', 'considered', 'amenable', 'to', 'defibrillation.'], ['Chest', 'compressions', 'and', 'ventilations', 'are', 'being', 'performed,', 'a', 'defibrillator', 'shock', 'has', 'been', 'delivered,', 'and', 'a', 'peripheral', 'venous', 'line', 'has', 'been', 'cannulated.'], ['Which', 'of', 'the', 'following', 'would', 'be', 'correct', 'next:'], ['1-', 'Administration', 'of', '150', 'mg', 'of', 'intravenous', 'amiodarone.'], ['2-', 'Administration', 'of', '300', 'mg', 'of', 'intravenous', 'amiodarone.'], ['3-', 'Administration', 'of', '1', 'mg', 'of', 'intravenous', 'atropine.'], ['4-', 'Administer', '2', 'mg', 'of', 'intravenous', 'atropine.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['Controversial', 'question,', 'since', 'amiodarone', '(the', 'dose', 'is', 'correct,', '300mg),', 'is', 'administered', 'after', 'the', 'third', 'shock,', 'and', 'not', 'after', 'the', 'first', 'defibrillation,', 'which', 'is', 'what', 'we', 'are', 'told', 'in', 'the', 'statement.'], ['Although,', 'be', 'careful,', 'that', 'is', 'what', 'the', 'guidelines', 'say.'], ['I', 'am', 'sure', 'that', 'more', 'than', 'one', 'of', 'us', 'has', 'administered', 'amiodarone', 'as', 'soon', 'as', 'we', 'have', 'had', 'venous', 'access', 'available', 'in', 'the', 'event', 'of', 'a', 'shockable', 'rhythm.'], ['The', 'other', 'options', 'are', 'incorrect.']]
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113_93
[['QUESTION', 'TYPE:', 'HEMATOLOGY'], ['CLINICAL', 'CASE:'], ['A', '35-year-old', 'healthy', 'woman', 'consults', 'for', 'asthenia.'], ['The', 'CBC', 'shows', 'microcytic', 'and', 'hypochromic', 'anemia', '(hemoglobin', '7', 'g/dL,', 'mean', 'corpuscular', 'volume', '68', 'fl,', 'mean', 'corpuscular', 'hemoglobin', '24', 'pg)', 'with', 'an', 'elevated', 'red', 'cell', 'distribution', 'amplitude', '(ADE', '20%),', 'decreased', 'reticulocytes', '(0.3%,', '30000/l', 'absolute),', 'decreased', 'hemoglobin', 'content', 'in', 'reticulocytes', '(17', 'pg)', 'and', 'discrete', 'thrombocytosis', '(500000', 'platelets).'], ['With', 'the', 'CBC', 'data,', 'what', 'would', 'be', 'your', 'diagnostic', 'suspicion', 'even', 'without', 'having', 'the', "patient's", 'biochemistry?'], ['1-', 'Thalassemic', 'trait.'], ['2-', 'Central', 'anemia,', 'arregenerative,', 'due', 'to', 'folic', 'acid', 'deficiency.'], ['3-', 'Peripheral,', 'regenerative,', 'hemolytic', 'anemia.'], ['4-', 'Peripheral', 'anemia,', 'regenerative,', 'due', 'to', 'acute', 'active', 'hemorrhage.'], ['5-', 'Central', 'anemia,', 'arregenerative,', 'due', 'to', 'iron', 'deficiency.'], ['CORRECT', 'ANSWER:', '5'], ['With', 'the', 'data', 'we', 'are', 'given,', 'the', 'first', 'thing', 'that', 'comes', 'to', 'mind', 'is', 'that', 'it', 'is', 'an', 'arregenerative', 'anemia,', 'since', 'the', 'bone', 'marrow', 'has', 'not', 'responded', 'with', 'an', 'exaltation', 'of', 'erythropoiesis;', 'in', 'this', 'way', 'we', 'have', 'already', 'eliminated', 'the', 'options', 'that', 'speak', 'of', 'regenerative', 'anemia.'], ['The', 'next', 'thing', 'that', 'orients', 'us', 'towards', 'the', 'cause', 'is', 'that', 'it', 'is', 'microcytic', 'and', 'hypochromic,', 'which', 'is', 'characteristic', 'of', 'iron', 'deficiency', 'anemia,', 'since', 'folic', 'deficiency', 'gives', 'rise', 'to', 'megaloblastic', 'anemia', 'and', 'active', 'hemorrhage', 'does', 'not', 'give', 'microcytosis', 'or', 'hypochromia,', 'but', 'normocytosis', 'and', 'normochromia.'], ['We', 'are', 'almost', 'inclined', 'to', 'answer', '5,', 'central', 'arregenerative', 'anemia', 'due', 'to', 'iron', 'deficiency...but', 'there', 'remains', 'answer', '1,', '"thalassemic', 'trait",', 'which', 'makes', 'us', 'uncomfortable', 'and', 'makes', 'us', 'doubt', 'if', 'we', 'are', 'not', 'going', 'for', 'the', 'apparently', 'easy', 'thing...until', 'we', 'remember', 'that', 'in', 'thalassemia', 'the', 'ADE', 'is', 'normal.'], ['Definitely,', 'this', 'girl', 'of', 'childbearing', 'age', 'has', 'iron', 'deficiency', 'anemia,', 'something', 'quite', 'common.'], ['Those', 'who', 'have', 'doubts', 'can', 'consult', '"Hematology.'], ['Manual', 'básico', 'razonado"', 'by', 'Jesús', 'San', 'Miguel.']]
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59_51
[['QUESTION', 'TYPE:', 'ANESTHESIOLOGY', 'AND', 'CRITICAL', 'CARE'], ['CLINICAL', 'CASE:'], ['A', '47-year-old', 'male', 'patient', 'who', 'consults', 'the', 'emergency', 'department', 'for', 'sudden', 'loss', 'of', 'consciousness', 'Which', 'of', 'the', 'following', 'has', 'a', 'higher', 'diagnostic', 'yield?'], ['1-', 'Clinical', 'history.'], ['2-', 'Electrocardiogram.'], ['3-', 'Holter', 'recording.'], ['4-', 'EEG.'], ['5-', 'Cranial', 'CT', 'scan.'], ['CORRECT', 'ANSWER:', '1'], ['Obviously,', 'it', 'is', 'the', 'only', 'answer', 'that', 'encompasses', 'all', 'the', 'causes', 'of', 'sudden', 'loss', 'of', 'consciousness', 'and', 'that', 'allows', 'us', 'to', 'somehow', 'filter', 'the', 'diagnosis.']]
[['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]
412_54
[['QUESTION', 'TYPE:', 'BIOSTATISTICS'], ['CLINICAL', 'CASE:'], ['Elizabeth', 'has', 'three', 'sons', 'and', 'one', 'daughter', '(Mary),', 'all', 'of', 'whom', 'are', 'healthy.'], ['A', 'brother', 'and', 'a', 'maternal', 'uncle', 'of', 'Isabel', 'died', 'of', 'Duchenne', 'disease:', 'an', 'X-linked', 'recessive', 'disease.'], ['At', 'present,', 'Maria', 'wants', 'to', 'become', 'pregnant', 'and', 'wants', 'to', 'know', 'the', 'risk', 'of', 'transmitting', 'the', 'disease', 'to', 'her', 'offspring.'], ['With', 'the', 'data', 'collected,', 'what', 'is', 'the', 'probability', 'that', 'Maria', 'is', 'a', 'carrier', 'of', 'Duchenne', 'disease?'], ['1-', '2/3.'], ['2-', '1/2.'], ['3-', '1/4.'], ['4-', 'Less', 'than', '1/4.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['The', 'maternal', 'grandmother', 'carried', 'the', 'mutation', 'in', 'one', 'copy', 'of', 'the', 'gene', 'on', 'an', 'X', 'chromosome', '(we', 'are', 'not', 'told', 'that', 'she', 'had', 'the', 'disease,', 'but', 'a', 'son', 'of', 'hers,', "Isabel's", 'maternal', 'uncle,', 'did', 'have', 'the', 'disease).'], ["Isabel's", 'mother', 'continues', 'to', 'carry', 'it,', 'since', 'one', 'of', "Isabel's", 'brothers', 'has', 'suffered', 'from', 'the', 'disease', 'but', 'not', 'her', 'father.'], ['Thus,', 'Isabel', 'has', 'a', '50%', 'chance', 'of', 'having', 'inherited', 'the', 'mutated', 'gene', 'from', 'her', 'mother', '(as', 'her', 'children', 'are', 'all', 'healthy,', 'we', 'are', 'not', 'sure', 'if', 'she', 'is', 'a', 'carrier),', 'and', 'therefore', 'her', 'daughter', 'has', 'a', '25%', 'chance', 'of', 'having', 'inherited', 'the', 'mutated', 'gene', 'from', 'her', 'grandmother.']]
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347_159
[['QUESTION', 'TYPE:', 'GYNECOLOGY', 'AND', 'OBSTETRICS'], ['CLINICAL', 'CASE:'], ['69-year-old', 'woman', 'who', 'comes', 'to', 'your', 'office', 'referring', 'genital', 'bleeding', 'of', 'several', 'months', 'of', 'evolution.'], ['She', 'denies', 'hormone', 'replacement', 'therapy', 'and', 'anticoagulation.'], ['She', 'provides', 'normal', 'cervicovaginal', 'cytology.'], ['General', 'and', 'genital', 'physical', 'examination', 'without', 'findings', 'of', 'interest.'], ['BMI', 'of', '38kg/m2.'], ['Indicate', 'the', 'most', 'correct', 'attitude:'], ['1-', 'Prescribe', 'cyclic', 'progesterone.'], ['2-', 'Endometrial', 'biopsy.'], ['3-', 'Random', 'biopsies', 'of', 'the', 'cervix.'], ['4-', 'Hormonal', 'assessment', 'with', 'FSH,', 'LH', 'and', 'estradiol.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['Endometrial', 'biopsy.'], ['Peri-', 'or', 'menopause:', '-', 'Due', 'to', 'the', 'high', 'prevalence', 'of', 'organic', 'pathology', 'during', 'this', 'period', 'it', 'is', 'necessary', 'to', 'systematically', 'perform', 'endometrial', 'biopsy', '(Cornier', 'or', 'Hysteroscopy).']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
325_56
[['QUESTION', 'TYPE:', 'CRITICAL,', 'PALLIATIVE', 'AND', 'EMERGENCY', 'CARE'], ['CLINICAL', 'CASE:'], ['A', '54-year-old', 'patient', 'is', 'admitted', 'for', 'thermometric', 'fever', 'of', '38°C', 'in', 'the', 'previous', 'five', 'days', 'and', 'dyspnea', 'at', 'rest', '(NYHA', 'lV)', 'that', 'appeared', '6', 'hours', 'before', 'coming', 'to', 'the', 'hospital.'], ['Examination', 'in', 'the', 'emergency', 'room', 'was', 'compatible', 'with', 'heart', 'failure', 'and', 'the', 'ECG', 'showed', 'complete', 'atrioventricular', 'block', 'with', 'an', 'escape', 'ventricular', 'rate', 'of', '45', 'bpm.'], ['Signs', 'of', 'heart', 'failure', 'are', 'refractory', 'to', 'medical', 'treatment', 'and', 'transesophageal', 'echocardiography', 'shows', 'an', 'aortic', 'valve', 'with', 'an', 'effective', 'regurgitant', 'orifice', 'of', '0.5', 'cm2.'], ['Serial', 'cultures', 'are', 'positive', 'for', 'Streptococcus', 'gallolyticus.'], ['Indicate', 'the', 'best', 'course', 'of', 'action:'], ['1-', 'Cardiac', 'surgery', 'for', 'aortic', 'valve', 'replacement', 'by', 'mechanical', 'prosthesis', 'with', 'antibiotic', 'therapy', 'according', 'to', 'antibiogram.'], ['2-', 'Antibiotic', 'therapy', 'according', 'to', 'antibiogram', 'and', 'implantation', 'of', 'intra-aortic', 'balloon', 'counterpulsation', 'and', 'transient', 'pacemaker', 'for', 'up', 'to', '3', 'weeks,', 'after', 'which', 'a', 'permanent', 'pacemaker', 'will', 'be', 'implanted.'], ['3-', 'Implantation', 'of', 'transient', 'pacemaker,', 'antibiotic', 'therapy', 'according', 'to', 'antibiogram', 'and', 'percutaneous', 'implantation', 'of', 'aortic', 'valve', 'prosthesis.'], ['4-', 'Urgent', 'implantation', 'of', 'definitive', 'pacemaker', 'with', 'antibiotic', 'therapy', 'according', 'to', 'antibiogram', 'for', '6', 'weeks.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['The', 'correct', 'answer', 'is', '1,', 'since', 'the', 'indications', 'for', 'cardiac', 'surgery', 'include', 'the', 'appearance', 'of', 'heart', 'failure', 'or', 'new', 'conduction', 'disorders,', 'and', 'in', 'this', 'case', 'it', 'presents', 'both.']]
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335_175
[['QUESTION', 'TYPE:', 'PHARMACOLOGY'], ['CLINICAL', 'CASE:'], ['An', '88-year-old', 'man', 'comes', 'for', 'consultation', 'because', 'he', 'has', 'fallen', '3', 'times', 'in', 'the', 'last', '6', 'months.'], ['None', 'of', 'the', 'falls', 'was', 'accompanied', 'by', 'dizziness', 'or', 'syncope.'], ['One', 'fall', 'occurred', 'while', 'he', 'was', 'walking', 'in', 'the', 'garden.'], ['His', 'medical', 'history', 'includes', 'hypertension', 'without', 'postural', 'changes', 'in', 'blood', 'pressure,', 'gout,', 'osteoarthritis,', 'and', 'depression.'], ['She', 'takes', '5', 'medications', 'regularly.'], ['Which', 'of', 'the', 'following', 'is', 'most', 'likely', 'to', 'contribute', 'to', 'falls', 'in', 'this', 'patient?'], ['1-', 'Allopurinol.'], ['2-', 'Hydrochlorothiazide.'], ['3-', 'Lisinopril.'], ['4-', 'Paroxetine.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['Paroxetine;', 'complicated', 'question', 'since', 'both', 'hydrochlorothiazide', 'and', 'lisinopril', 'can', 'also', 'produce', 'falls', 'in', 'the', 'elderly,', 'but', 'they', 'would', 'generally', 'be', 'accompanied', 'by', 'dizziness.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'O', 'O', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
19_109
[['QUESTION', 'TYPE:', 'INFECTIOUS', 'DISEASES'], ['CLINICAL', 'CASE:'], ['A', '32-year-old', 'woman', 'has', 'traveled', 'to', 'Cuba', 'from', 'where', 'she', 'arrived', 'three', 'days', 'ago.'], ['The', 'day', 'after', 'her', 'return,', 'she', 'goes', 'to', 'her', 'family', 'doctor', 'for', 'high', 'fever,', 'intense', 'arthromyalgia', 'and', 'headache', 'that', 'had', 'started', 'before', 'the', 'return', 'trip', 'and', 'he', 'prescribes', 'her', 'paracetamol.'], ['Three', 'days', 'later', 'and', 'with', 'no', 'improvement,', 'he', 'presented', 'in', 'the', 'morning', 'with', 'a', 'generalized', 'pruritic', 'maculo-papular', 'rash,', 'which', 'was', 'more', 'intense', 'on', 'the', 'lower', 'limbs', 'where', 'it', 'developed', 'into', 'petechiae,', 'for', 'which', 'he', 'went', 'to', 'the', 'emergency', 'department.'], ['There', 'is', 'no', 'relevant', 'data', 'in', 'the', 'EC', 'except', 'platelets', '75000/mm3', '(htco', '36%,', 'leukocytes', '4100', '79%', 'neutrophils).'], ['What', 'is', 'the', 'most', 'likely', 'diagnosis?'], ['1-', 'Infectious', 'mononucleosis.'], ['2-', 'Allergic', 'exanthema.'], ['3-', 'P.', 'falciparum', 'malaria.'], ['4-', 'Typhoid', 'fever.'], ['5-', 'Dengue', 'fever.'], ['CORRECT', 'ANSWER:', '5'], ['In', 'this', 'case', 'I', 'believe', 'that', 'the', 'correct', 'answer', 'is', '5.'], ['The', '1', 'should', 'not', 'be', 'because', 'although', 'the', 'clinical', 'picture', 'is', 'suggestive,', 'it', 'does', 'not', 'present', 'lymphocytosis.'], ['It', 'does', 'not', 'seem', 'to', 'be', 'an', 'allergic', 'exanthema', 'from', 'the', 'clinical', 'picture.'], ['And', 'certainly', 'she', 'does', 'not', 'have', 'symptoms', 'or', 'clinical', 'signs', 'compatible', 'with', 'malaria', 'or', 'typhoid', 'fever.'], ['What', 'points', 'to', 'dengue,', 'in', 'addition', 'to', 'the', 'clinical', 'signs,', 'is', 'the', 'plateletopenia.']]
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401_147
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY', 'AND', 'ORTHOPEDICS'], ['CLINICAL', 'CASE:'], ['A', '13-year-old', 'boy', 'presents', 'dorsal', 'pain', 'of', 'several', 'months', 'of', 'evolution,', 'only', 'when', 'standing', 'and', 'walking,', 'what', 'diagnosis', 'should', 'we', 'consider?'], ['1-', "Scheuermann's", 'disease.'], ['2-', 'Thoracic', 'scoliosis.'], ['3-', 'Malignant', 'tumor', 'of', 'the', 'vertebral', 'body.'], ['4-', 'It', 'is', 'a', 'mechanical', 'overload.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['A', 'malignant', 'tumor', 'would', 'also', 'hurt', 'at', 'rest.'], ['As', 'for', 'Scheuermann', 'and', 'scoliosis,', 'we', 'should', 'be', 'given', 'some', 'physical', 'data', 'because', 'the', 'patient', 'presents', 'with', 'a', 'specific', 'examination', 'that', 'would', 'give', 'us', 'the', 'diagnosis.']]
[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Marker', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
607_115
null
null
453_150
[['QUESTION', 'TYPE:', 'NEUROLOGY'], ['CLINICAL', 'CASE:'], ['A', '25-year-old', 'man', 'consults', 'for', 'tremor.'], ['Examination', 'reveals', 'dysarthria', 'and', 'dystonia.'], ['He', 'has', 'a', 'family', 'history', 'of', 'psychiatric', 'illness', 'and', 'movement', 'disorders.'], ['Which', 'diagnostic', 'test', 'do', 'you', 'consider', 'most', 'accurate?'], ['1-', 'DATS', 'CAN.'], ['2-', 'Nerve', 'conduction', 'study.'], ['3-', 'Electroencephalogram.'], ['4-', 'Copper', 'in', 'urine', 'of', '24.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['If', 'they', 'are', 'talking', 'about', 'a', 'young', 'man', '20-30', 'years', 'old,', 'with', 'tremor', 'and', 'dystonia,', 'whether', 'or', 'not', 'he', 'has', 'a', 'family', 'history,', 'and', 'especially', 'if', 'one', 'of', 'the', 'options', 'tells', 'me', 'about', 'copper', 'in', 'urine,', 'they', 'are', 'telling', 'me', 'to', 'think', 'of', "Wilson's", 'disease.'], ['I', 'do', 'not', 'think', 'of', 'juvenile', "Parkinson's,", 'nor', 'an', 'epileptic', 'clinic.'], ['So', 'the', 'correct', 'answer', 'is', '4.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
529_166
[['QUESTION', 'TYPE:', 'NEPHROLOGY'], ['CLINICAL', 'CASE:'], ['An', '18-year-old', 'patient', 'consulted', 'for', 'edema.'], ['A', 'complete', 'blood', 'test', 'showed', 'proteinuria', 'of', '8', 'g/day', 'without', 'microhematuria,', 'hypoalbuminemia', 'and', 'hypercholesterolemia', 'with', 'normal', 'renal', 'function.'], ['He', 'was', 'empirically', 'administered', 'corticosteroids.'], ['After', 'one', 'month,', 'the', 'clinical', 'picture', 'has', 'completely', 'disappeared.'], ['What', 'is', 'your', 'diagnostic', 'hypothesis?'], ['1-', 'Amyloidosis.'], ['2-', 'IgA', 'nephropathy', 'or', "Berger's", 'disease.'], ['3-', 'Alport', 'syndrome.'], ['4-', 'Nephropathy', 'with', 'minimal', 'changes.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['We', 'describe', 'a', 'young', 'patient', 'with', 'criteria', 'of', 'nephrotic', 'syndrome', 'with', 'excellent', 'response', 'to', 'corticosteroids.'], ['Without', 'biopsy,', 'the', 'clinical', 'presentation', 'and', 'evolution', 'suggest', 'a', 'nephropathy', 'with', 'minimal', 'changes,', 'which', 'usually', 'presents', 'with', 'normal', 'or', 'slightly', 'altered', 'renal', 'function', 'together', 'with', 'nephrotic', 'syndrome,', 'and', 'which', 'in', '85-90%', 'of', 'cases', 'resolves', 'with', 'steroid', 'treatment.'], ['The', 'age', 'is', 'the', 'only', 'data', 'that', 'is', 'a', 'bit', 'shaky,', 'since', 'although', 'it', 'is', 'the', 'most', 'frequent', 'cause', 'of', 'idiopathic', 'nephrotic', 'syndrome', 'in', 'children', 'and', 'adolescents,', 'it', 'is', 'usually', 'recommended', 'to', 'perform', 'a', 'biopsy', 'prior', 'to', 'treatment', 'in', 'those', 'older', 'than', '16', 'years,', 'in', 'any', 'case', 'it', 'does', 'not', 'admit', 'much', 'discussion.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
258_96
[['QUESTION', 'TYPE:', 'ENDOCRINOLOGY'], ['CLINICAL', 'CASE:'], ['A', '62-year-old', 'man', 'with', 'type', '2', 'diabetes', 'mellitus', 'of', '10', 'years', 'of', 'evolution', 'is', 'treated', 'with', 'metformin', 'and', 'sitagliptin.'], ['He', 'does', 'little', 'physical', 'exercise', 'and', 'follows', 'an', 'adequate', 'diet.'], ['In', 'the', 'last', '6', 'months', 'he', 'has', 'lost', 'weight', 'and', 'has', 'more', 'asthenia.'], ['Her', 'glycemic', 'controls', 'have', 'deteriorated', 'from', 'baseline', 'blood', 'glucose', 'levels', 'of', '110-140', 'mg/dL', 'to', '170-200', 'mg/dL,', 'as', 'well', 'as', 'her', 'glycosylated', 'hemoglobin', 'which', 'has', 'gone', 'from', '7.1', 'to', '8.5%.'], ['The', 'most', 'appropriate', 'therapeutic', 'measure', 'to', 'be', 'taken', 'is:'], ['1-', 'Increase', 'dietary', 'protein', 'and', 'long-chain', 'carbohydrate', 'intake', 'to', 'improve', 'asthenia', 'and', 'weight', 'loss.'], ['2-', 'To', 'associate', 'a', 'basal', 'insulin', 'dose', 'to', 'the', 'treatment.'], ['3-', 'Associate', 'with', 'ascarbose', 'treatment.'], ['4-', 'Substitute', 'sitagliptin', 'for', 'pioglitazone.'], ['5-', 'Substitute', 'metformin', 'for', 'glimepiride.'], ['CORRECT', 'ANSWER:', '2'], ['To', 'associate', 'a', 'basal', 'insulin', 'dose', 'to', 'the', 'treatment.'], ['Expected', 'question', 'on', 'a', 'very', 'important', 'subject:', 'diabetes', 'and', 'its', 'treatment.'], ['Patient', 'poorly', 'controlled', 'with', 'metformin', 'and', 'sitagliptin', 'with', 'discrete', 'cardinal', 'symptoms', '(weight', 'loss,', 'asthenia).'], ['The', 'best', 'option', 'is', 'insulin', 'to', 'control', 'cardinal', 'symptoms', 'and', 'decrease', 'HbA1c', 'to', '<', '7%.']]
[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]
375_128
[['QUESTION', 'TYPE:', 'NEUROLOGY'], ['CLINICAL', 'CASE:'], ['A', '45-year-old', 'patient', 'under', 'study', 'for', 'possible', 'meningitis,', 'with', 'fever,', 'headache', 'and', 'vomiting', 'of', '2', 'days', 'of', 'evolution.'], ['A', 'brain', 'MRI', 'and', 'lumbar', 'puncture', 'were', 'performed.'], ['Twenty', 'hours', 'later,', 'on', 'getting', 'up', 'to', 'go', 'to', 'the', 'bathroom,', 'he', 'complains', 'of', 'severe', 'headache,', 'very', 'marked', 'when', 'he', 'sits', 'up', 'but', 'disappears', 'when', 'he', 'lies', 'down.'], ['She', 'no', 'longer', 'has', 'fever', 'or', 'vomiting.'], ['What', 'is', 'most', 'likely', 'the', 'origin', 'of', 'this', 'headache?'], ['1-', 'Meningitis', 'remains', 'the', 'fundamental', 'cause', 'of', 'her', 'headache,', 'as', 'it', 'is', 'the', 'same', 'type', 'of', 'headache', 'as', 'at', 'the', 'onset', 'of', 'symptoms.'], ['2-', 'It', 'is', 'a', 'post', 'lumbar', 'puncture', 'headache.'], ['3-', 'It', 'is', 'necessary', 'to', 'look', 'for', 'a', 'different', 'cause', 'to', 'this', 'headache,', 'because', 'it', 'is', 'not', 'typical', 'of', 'post-lumbar', 'puncture', 'syndrome', 'or', 'meningitis.'], ['4-', 'Most', 'likely', 'it', 'was', 'not', 'a', 'viral', 'meningitis,', 'but', 'a', 'subarachnoid', 'hemorrhage.', 'For', 'this', 'reason,', 'the', 'initial', 'headache', 'disappears', 'almost', 'completely', 'when', 'lying', 'down.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['The', 'picture', 'they', 'describe', 'of', 'intense', 'headache', 'with', 'orthostatism', 'that', 'disappears', 'when', 'lying', 'down,', 'although', 'it', 'is', 'true', 'that', 'the', 'most', 'typical', 'presentation', 'is', 'between', 'the', 'first', '24-48', 'hours', 'and', 'in', 'this', 'case', 'it', 'is', 'somewhat', 'earlier.'], ['Even', 'so,', 'the', 'rest', 'of', 'the', 'answers', 'are', 'improbable:', 'the', 'first', 'cannot', 'be', 'because', 'we', 'have', 'not', 'been', 'told', 'what', 'the', 'initial', 'headache', 'was', 'like;', 'the', 'third,', 'although', 'it', 'could', 'be', 'due', 'to', 'the', 'time', 'of', 'onset', '(as', 'I', 'said', 'a', 'little', 'earlier', 'than', 'expected),', 'the', 'reality', 'is', 'that', 'the', 'headache', 'with', 'orthostasis', 'is', 'so', 'typical', 'that', 'it', 'would', 'be', 'the', 'most', 'probable', 'cause;', 'the', 'last', 'one', 'could', 'not', 'be', 'either', 'because', 'SAH', 'does', 'not', 'follow', 'this', 'pattern', 'in', 'relation', 'to', 'orthostasis.']]
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352_161
[['QUESTION', 'TYPE:', 'GYNECOLOGY', 'AND', 'OBSTETRICS'], ['CLINICAL', 'CASE:'], ['A', '27-year-old', 'woman', 'referred', 'to', 'the', 'gynecology', 'office', 'for', 'evaluation', 'referring', 'dyspareunia', 'for', 'about', '8', 'months,', 'along', 'with', 'dyschezia', 'and', 'occasional', 'rectorrhagia', 'coinciding', 'with', 'menstruation', 'for', '3-4', 'months.'], ['She', 'also', 'reports', 'dysmenorrhea', 'for', 'years,', 'which', 'she', 'controls', 'well', 'with', 'ibuprofen.'], ['She', 'has', 'been', 'trying', 'to', 'get', 'pregnant', 'for', '16', 'months', 'without', 'success.'], ['In', 'the', 'gynecological', 'examination', 'she', 'only', 'shows', 'pain', 'when', 'pressing', 'on', 'the', 'posterior', 'vaginal', 'fornix.'], ['Which', 'test', 'do', 'you', 'consider', 'would', 'allow', 'you', 'to', 'reach', 'a', 'diagnosis', 'of', 'certainty', 'of', 'her', 'pathology?'], ['1-', 'Transvaginal', 'ultrasound.'], ['2-', 'Diagnostic', 'laparoscopy.'], ['3-', 'Magnetic', 'resonance', 'imaging.'], ['4-', 'Colonoscopy.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['The', 'correct', 'answer', 'is', '2.'], ['We', 'are', 'facing', 'a', 'suspicion', 'of', 'endometriosis,', 'due', 'to', 'the', 'symptoms', 'and', 'signs', 'given', 'in', 'the', 'statement.'], ['We', 'are', 'asked', 'for', 'a', 'diagnosis', 'of', 'certainty,', 'and', 'the', 'Gold', 'Standard', 'for', 'the', 'diagnosis', 'of', 'this', 'disease', 'is', 'diagnostic', 'laparoscopy.']]
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575_102
[['QUESTION', 'TYPE:', 'NEUROLOGY'], ['CLINICAL', 'CASE:'], ['A', '29-year-old', 'woman', 'with', 'a', 'history', 'of', 'febrile', 'seizures', 'and', 'a', 'heavy', 'smoker.'], ['She', 'consults', 'for', 'frequent,', 'stereotyped', 'episodes', 'that', 'begin', 'with', 'an', 'ascending', 'epigastric', 'sensation', 'and', 'an', 'unpleasant', 'odor,', 'followed', 'by', 'disconnection', 'from', 'the', 'environment.'], ['Family', 'members', 'who', 'are', 'with', 'her', 'observe', 'that', 'she', 'makes', 'sucking', 'movements', 'and', 'repeated', 'opening', 'and', 'closing', 'movements', 'of', 'the', 'left', 'hand.'], ['After', 'two', 'minutes', 'the', 'movements', 'subside,', 'but', 'she', 'has', 'difficulty', 'responding', 'appropriately', 'and', 'only', 'partially', 'remembers', 'what', 'happened.'], ['Which', 'of', 'the', 'following', 'is', 'the', 'most', 'likely', 'diagnosis?'], ['1-', 'Complex', 'focal', 'temporal', 'lobe', 'seizures.'], ['2-', 'Transient', 'ischemic', 'attacks', 'in', 'right', 'carotid', 'territory.'], ['3-', 'Simple', 'focal', 'motor', 'seizures.'], ['4-', 'Episodes', 'of', 'transient', 'global', 'amnesia.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['The', 'clinical', 'case', 'makes', 'a', 'textbook', 'description', 'of', 'a', 'medial', 'temporal', 'seizure.'], ['The', 'aura', 'of', 'ascending', 'epigastric', 'sensation', 'and', 'olfactory', 'alteration', 'and', 'the', 'subsequent', 'description', 'of', 'the', 'seizure', 'with', 'alteration', 'of', 'the', 'level', 'of', 'consciousness', '(disconnection', 'from', 'the', 'environment)', 'with', 'oral', 'and', 'manual', 'automatisms.'], ['The', 'current', 'classification', 'is', 'the', '2017', 'ILAE', 'classification', 'that', 'would', 'describe', 'this', 'seizure', 'as', 'focal', 'seizure', 'with', 'altered', 'level', 'of', 'consciousness,', 'but', 'in', 'the', 'MIR', 'they', 'still', 'use', 'the', 'old', 'terminology', '(complex', 'is', 'what', 'altered', 'level', 'of', 'consciousness', 'was', 'called).']]
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278_31
[['QUESTION', 'TYPE:', 'PATHOLOGICAL', 'ANATOMY'], ['CLINICAL', 'CASE:'], ['A', '20-year-old', 'woman', 'with', 'a', '15', 'cm', 'solid-cystic', 'ovarian', 'tumor', 'detected', 'by', 'ultrasound', 'after', 'presenting', 'with', 'non-specific', 'abdominal', 'symptoms.'], ['In', 'the', 'anatomopathological', 'study', 'of', 'the', 'corresponding', 'specimen,', 'teeth,', 'hairs,', 'areas', 'of', 'intestinal', 'epithelium,', 'areas', 'of', 'squamous', 'epithelium', '(15%)', 'and', 'bronchial', 'epithelium,', 'as', 'well', 'as', 'neuroectodermal', 'and', 'embryonic', 'elements', 'are', 'found', 'in', 'several', 'of', 'the', 'histological', 'preparations.'], ['In', 'reference', 'to', 'this', 'case,', 'point', 'out', 'the', 'correct', 'diagnosis:'], ['1-', 'Teratocarcinoma.'], ['2-', 'Immature', 'teratoma.'], ['3-', 'Mature', 'cystic', 'teratoma.'], ['4-', 'Dysgerminoma.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '2'], ['After', 'reading', 'the', 'question', 'and', 'the', 'possible', 'answers,', 'we', 'have', 'two', 'tumor', 'and', 'two', 'non-tumor', 'options.'], ['At', 'no', 'time', 'are', 'atypical', 'cellular', 'features', 'mentioned,', 'so', 'we', 'can', 'safely', 'rule', 'out', 'tumor', 'lesions,', 'leaving', 'doubts', 'between', 'answers', '2', 'and', '3.'], ['In', 'this', 'case,', 'we', 'would', 'have', 'to', 'opt', 'for', 'IMMATURE', 'TERATOMA,', 'mentioning', 'the', 'presence', 'of', 'embryonic', 'remains.']]
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225_64
[['QUESTION', 'TYPE:', 'CARDIOLOGY'], ['CLINICAL', 'CASE:'], ['An', '82-year-old', 'patient', 'presents', 'with', 'sudden', 'and', 'frequent', 'dizziness,', 'without', 'prodromes,', 'of', 'short', 'duration', 'and', 'which', 'subsides', 'spontaneously,', 'without', 'ever', 'presenting', 'syncope.'], ['Physical', 'examination', 'and', 'baseline', 'electrocardiogram', 'are', 'normal.'], ['In', 'an', 'ambulatory', 'electrocardiogram', 'recording', 'during', '24', 'hours,', 'short', 'phases', 'of', 'absence', 'of', 'P', 'waves', 'prior', 'to', 'QRS', 'with', 'an', 'escape', 'rhythm', 'of', 'the', 'atrioventricular', 'junction', 'with', 'narrow', 'QRS', 'at', '40', 'bpm', 'and', 'a', 'wave', 'at', 'the', 'beginning', 'of', 'the', 'ST', 'segment', 'corresponding', 'to', 'a', 'retrograde', 'P', 'were', 'detected', 'in', 'the', 'vigil', 'period.'], ['No', 'asystole', 'periods', 'longer', 'than', '3', 'seconds', 'are', 'detected.'], ['Given', 'this', 'you', 'would', 'say:'], ['1-', 'The', 'patient', 'has', 'a', 'third-degree', 'AVB', 'and', 'requires', 'pacemaker', 'implantation.'], ['2-', 'The', 'absence', 'of', 'periods', 'of', 'asystole', '>3', 'seconds', 'excludes', 'a', 'cardiac', 'cause', 'of', 'dizziness.'], ['3-', 'Drug', 'treatment', 'to', 'increase', 'conduction', 'in', 'the', 'AV', 'node', 'would', 'be', 'indicated.'], ['4-', 'The', 'patient', 'presents', 'sinus', 'dysfunction', 'with', 'sinoatrial', 'block', 'and', 'requires', 'pacemaker', 'implantation', 'due', 'to', 'symptoms.'], ['5-', 'The', 'alterations', 'detected', 'in', 'the', 'ambulatory', 'electrocardiogram', 'are', 'typical', 'of', 'patients', 'of', 'this', 'age', 'and', 'there', 'is', 'no', 'indication', 'for', 'therapeutic', 'intervention.'], ['CORRECT', 'ANSWER:', '5'], ['What', 'are', 'these', 'findings', 'in', 'the', 'Holter?'], ['If', 'the', 'sinus', 'node', 'fails,', 'the', 'AV', 'node', 'takes', 'over', 'and', 'stimulates', 'the', 'ventricle.'], ['In', '10%', 'of', 'people', 'there', 'is', 'retrograde', 'conduction,', 'so', 'that', 'beat', 'generated', 'in', 'the', 'AVN', 'stimulates', 'both', 'ventricles', 'and', 'atria,', 'giving', 'a', 'retrograde', 'P', 'as', 'reported', 'in', 'the', 'study.'], ['In', 'this', 'sense,', 'no', 'problem.'], ['Likewise,', 'there', 'are', 'also', 'no', 'pauses', 'longer', 'than', '3', 'seconds', 'that', 'could', 'cause', 'cardiogenic', 'syncope', '(which,', 'in', 'fact,', 'he', 'has', 'never', 'suffered).'], ['Option', '1', 'is', 'ruled', 'out:', 'it', 'is', 'not', 'a', 'complete', 'AVB.'], ['Option', '2', 'cannot', 'be', 'answered', 'either:', 'to', 'exclude,', 'what', 'is', 'said', 'to', 'exclude...'], ['It', 'is', 'like', 'never/always.'], ['Option', '3', 'does', 'not', 'make', 'much', 'sense:', 'we', 'could', 'suspend', 'those', 'that', 'impair', 'conduction', '(beta-blockers,', 'calcium', 'antagonists),', 'but', 'drugs', 'that', 'facilitate,', 'as', 'long', 'as', 'we', 'do', 'not', 'give', 'him', 'a', 'perfusion', 'of', 'atropine', 'to', 'take', 'home...'], ['In', 'option', '4,', 'stating', 'that', 'he', 'has', 'sinoatrial', 'block', 'is', 'a', 'bit', 'of', 'a', 'rap:', 'without', 'an', 'electrophysiological', 'study', 'it', 'cannot', 'be', 'said,', 'he', 'does', 'not', 'necessarily', 'have', 'SA', 'block,', 'and', 'this', 'alone', 'would', 'not', 'indicate', 'the', 'implantation', 'of', 'a', 'pacemaker.'], ['So,', 'finally,', 'I', 'would', 'check', 'option', '5.']]
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370_125
[['QUESTION', 'TYPE:', 'PULMONOLOGY', 'AND', 'THORACIC', 'SURGERY'], ['CLINICAL', 'CASE:'], ['A', 'former', 'smoker', 'patient,', 'previously', 'diagnosed', 'with', 'COPD', 'comes', 'in', 'for', 'a', 'checkup.'], ['The', 'physical', 'examination', 'reveals', 'digital', 'hypokratism', 'of', 'recent', 'onset.'], ['What', 'is', 'the', 'most', 'acceptable', 'explanation', 'for', 'this', 'finding', 'in', 'the', 'clinical', 'context', 'described?'], ['1-', 'Pulmonary', 'carcinoma.'], ['2-', 'Bronchiectasis.'], ['3-', 'Pulmonary', 'fibrosis.'], ['4-', 'Cyanotic', 'heart', 'disease.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['In', 'a', 'digital', 'hypokratitis', 'of', 'recent', 'onset', 'in', 'a', 'smoking', 'patient,', 'the', 'first', 'option', 'to', 'rule', 'out', 'is', 'bronchopulmonary', 'carcinoma.'], ['Other', 'pathologies', 'can', 'also', 'occur', 'but', 'not', 'so', 'suddenly.']]
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332_88
null
null
78_33
[['QUESTION', 'TYPE:', 'DIGESTIVE', 'SYSTEM'], ['CLINICAL', 'CASE:'], ['A', '55-year-old', 'postmenopausal', 'woman', 'consults', 'for', 'asthenia', 'and', 'dyspnea', 'on', 'exertion.'], ['In', 'the', 'anamnesis', 'she', 'reported', 'slight', 'epigastralgia', 'and', 'occasional', 'heartburn.'], ['No', 'metrorrhagia.'], ['Laboratory', 'tests:', 'Hb6', 'gr/dL,', 'MCV', '69', 'fl,', 'sideremia', '13', 'micrograms/dL,', 'ferritin', '4', 'ngr/mL.'], ['Gastrointestinal', 'endoscopy:', 'small', 'sliding', 'hiatal', 'hernia', 'with', 'no', 'signs', 'of', 'esophagitis.'], ['What', 'is', 'the', 'most', 'correct', 'approach?'], ['1-', 'Administer', 'oral', 'iron', 'and', 'monitor', 'the', 'evolution', 'of', 'anemia.'], ['2-', 'Treat', 'with', 'proton', 'pump', 'inhibitors', 'and', 'evaluate', 'at', 'three', 'months.'], ['3-', 'Recommend', 'a', 'complete', 'colonoscopy.'], ['4-', 'Perform', 'an', 'endoscopic', 'capsule', 'study.'], ['5-', 'Request', 'a', 'gynecological', 'evaluation.'], ['CORRECT', 'ANSWER:', '3'], ['We', 'have', 'a', 'case', 'of', 'chronic', 'iron', 'deficiency', 'anemia,', 'without', 'obvious', 'bleeding.'], ['The', 'first', 'cause', 'of', 'iron', 'deficiency', 'anemia', 'is', 'occult', 'bleeding', 'of', 'digestive', 'origin.'], ['The', 'existence', 'of', 'clinical', 'symptoms', 'suggestive', 'of', 'pathology', 'of', 'the', 'upper', 'digestive', 'tract', 'has', 'led', 'us', 'to', 'begin', 'the', 'study', 'with', 'upper', 'endoscopy,', 'but', 'there', 'is', 'no', 'pathology', 'to', 'justify', 'the', 'anemia,', 'so', 'further', 'investigation', 'is', 'necessary,', 'which', 'rules', 'out', 'answers', '1', 'and', '2.'], ['Between', '3', 'and', '4,', 'large', 'bowel', 'lesions', 'are', 'much', 'more', 'common', 'and', 'should', 'be', 'ruled', 'out', 'before', 'small', 'bowel', 'lesions.'], ['In', 'fact', 'the', 'recommendations', 'of', 'capsule', 'endoscopy', 'in', 'anemia', 'studies', 'are', 'restricted.']]
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397_140
[['QUESTION', 'TYPE:', 'TRAUMATOLOGY', 'AND', 'ORTHOPEDICS'], ['CLINICAL', 'CASE:'], ['You', 'assess', 'a', '66-year-old', 'patient', 'with', 'accentuated', 'groin', 'pain', 'with', 'prolonged', 'standing', 'a', 'few', 'days', 'a', 'month.'], ['A', 'plain', 'radiograph', 'of', 'the', 'hips', 'shows', 'narrowing', 'of', 'the', 'femoroacetabular', 'joint', 'space,', 'sclerosis', 'and', 'osteophytes.'], ['What', 'is', 'your', 'attitude?'], ['1-', 'I', 'make', 'the', 'diagnosis', 'of', 'coxarthrosis', 'and', 'send', 'to', 'the', 'traumatologist', 'to', 'place', 'a', 'hip', 'prosthesis.'], ['2-', 'Start', 'treatment', 'with', 'weak', 'opioids', 'that', 'have', 'shown', 'evidence', 'of', 'halting', 'disease', 'progression.'], ['3-', 'I', 'instigate', 'treatment', 'with', 'paracetamol,', 'explain', 'that', 'the', 'evolution', 'is', 'very', 'variable', 'and', 'the', 'surgical', 'indication', 'depends', 'on', 'functionality', 'and', 'pain', 'control.'], ['4-', 'Because', 'of', 'the', 'radiological', 'features', 'described,', 'I', 'need', 'a', 'hip', 'MRI', 'before', 'making', 'a', 'therapeutic', 'decision.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['You', 'present', 'with', 'coxarthrosis', '(no', 'further', 'imaging', 'tests', 'are', 'needed),', 'and', 'conservative', 'options', 'are', 'exhausted', 'before', 'opting', 'for', 'surgical', 'treatment.'], ['Weak', 'opioids', 'are', 'not', 'the', 'initial', 'treatment', 'of', 'choice.']]
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275_74
[['QUESTION', 'TYPE:', 'DIGESTIVE', 'SYSTEM'], ['CLINICAL', 'CASE:'], ['A', '67-year-old', 'man,', 'diagnosed', 'with', 'cirrhosis', 'of', 'the', 'liver', 'and', 'an', 'active', 'drinker,', 'is', 'admitted', 'for', 'progressive', 'abdominal', 'distension', 'with', 'diffuse', 'malaise,', 'of', 'two', 'weeks', 'of', 'evolution.'], ['He', 'reported', 'no', 'fever', 'or', 'other', 'symptoms.'], ['On', 'examination,', 'there', 'was', 'a', 'changeable', 'dullness', 'on', 'abdominal', 'percussion,', 'with', 'absence', 'of', 'edema.'], ['A', 'diagnostic', 'paracentesis', 'is', 'performed,', 'finding', 'a', 'slightly', 'cloudy', 'fluid,', 'with', '2,300', 'cells/mL,', 'of', 'which', '30%', 'are', 'lymphocytes,', '60%', 'polymorphonuclear', 'and', '10%', 'red', 'blood', 'cells.'], ['What', 'is', 'the', 'first', 'therapeutic', 'measure', 'you', 'would', 'prescribe', 'for', 'this', 'patient', 'immediately?'], ['1-', 'Salt', 'and', 'fluid', 'restriction.'], ['2-', 'Diuretic', 'treatment', 'with', 'oral', 'spironolactone.'], ['3-', 'Treatment', 'with', 'a', 'third', 'generation', 'cephalosporin.'], ['4-', 'Evacuative', 'paracentesis.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '3'], ['This', 'is', 'spontaneous', 'bacterial', 'peritonitis', '(SBP),', 'defined', 'by', 'the', 'presence', 'of', '>', '250', 'polymorphonuclears/mL', 'in', 'the', 'ascitic', 'fluid', '(in', 'this', 'case', 'there', 'are', '1,380,', 'which', 'is', '60%', 'of', '2,300).'], ['It', 'is', 'an', 'indication', 'to', 'start', '3rd', 'generation', 'cephalosporins', '(ceftriaxone', 'or', 'cefotaxime)', 'and', 'albumin.'], ['The', 'rest', 'are', 'treatments', 'that', 'can', 'wait', 'for', 'improvement', '(they', 'do', 'not', 'speak', 'of', 'tension', 'ascites).']]
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418_77
[['QUESTION', 'TYPE:', 'GENERAL', 'SURGERY'], ['CLINICAL', 'CASE:'], ['An', '80-year-old', 'woman', 'comes', 'to', 'the', 'emergency', 'room', 'with', 'abdominal', 'pain', 'starting', 'in', 'the', 'epigastrium', 'and', 'radiating', 'later', 'to', 'the', 'left', 'iliac', 'fossa.'], ['An', 'abdominal', 'CT', 'scan', 'is', 'performed,', 'showing', 'inflammation', 'in', 'the', 'walls', 'of', 'the', 'sigma', 'and', 'mesenteric', 'abscess', 'of', '2', 'cm.'], ['The', 'treatment', 'of', 'choice', 'is:'], ['1-', 'Admission', 'to', 'the', 'ward', 'with', 'absolute', 'diet', 'and', 'broad-spectrum', 'antibiotic', 'treatment.'], ['2-', 'Discharge', 'colostomy.'], ['3-', 'Drainage', 'by', 'laparoscopic', 'surgery.'], ['4-', 'Urgent', 'surgery', 'with', 'sigmoidectomy', 'and', 'colorectal', 'anastomosis.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['We', 'are', 'asked', 'about', 'the', 'management', 'of', 'a', 'very', 'common', 'pathology,', 'diverticulitis.'], ['And', 'we', 'are', 'asked', 'about', 'the', 'different', 'therapeutic', 'options', 'depending', 'on', 'how', 'advanced', 'it', 'is.'], ['The', 'correct', 'answer', 'is', '1,', 'it', 'does', 'not', 'meet', 'the', 'criteria', 'to', 'require', 'drainage', 'by', 'guided', 'puncture', '(the', 'abscess', 'is', 'not', 'larger', 'than', '5-6', 'cm).'], ['Discharge', 'colostomy', 'in', 'this', 'case', 'makes', 'no', 'sense', 'whatsoever,', 'since', 'it', 'is', 'not', 'a', 'question', 'of', 'solving', 'an', 'obstructive', 'condition.'], ['Drainage', 'by', 'laparoscopic', 'surgery', 'is', 'not', 'indicated', 'in', 'this', 'case.'], ['It', 'could', 'be', 'indicated', 'in', 'the', 'absence', 'of', 'the', 'possibility', 'of', 'percutaneous', 'drainage', 'after', 'failure', 'of', 'conservative', 'treatment,', 'although', 'it', 'is', 'a', 'very', 'controversial', 'option', 'at', 'this', 'time.'], ['Sigmoidectomy', 'and', 'anastomosis', 'is', 'also', 'not', 'required.'], ['In', 'a', 'high', 'number', 'of', 'cases,', 'after', 'the', 'resolution', 'of', 'the', 'symptoms,', 'the', 'outbreaks', 'are', 'reduced', 'and', 'they', 'can', 'be', 'prevented', 'with', 'diet', 'and', 'hygienic', 'dietary', 'habits.']]
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200_75
null
null
469_137
[['QUESTION', 'TYPE:', 'ORTHOPEDIC', 'SURGERY', 'AND', 'TRAUMATOLOGY'], ['CLINICAL', 'CASE:'], ['93-year-old', 'woman', 'with', 'a', 'history', 'of', 'COPD,', 'AHT,', 'dyslipidemia,', 'atrial', 'fibrillation', 'and', 'ischemic', 'heart', 'disease.'], ['She', 'lives', 'alone.'], ['She', 'has', 'ventricular', 'ejection', 'fraction', '53%,', 'creatinine', '1.5', 'mg/dL,', 'normal', 'coagulation.'], ['She', 'receives', 'treatment', 'with', 'inhaled', 'bronchodilators', 'and', 'ASA', '100', 'mg', 'per', 'day.'], ['She', 'suffers', 'a', 'fall', 'in', 'the', 'street,', 'after', 'which', 'it', 'is', 'impossible', 'for', 'her', 'to', 'stand', 'or', 'sit', 'up,', 'with', 'intense', 'pain', 'in', 'the', 'right', 'hip', 'on', 'mobilization,', 'great', 'shortening', 'and', 'external', 'rotation', 'of', 'the', 'leg.'], ['When', 'and', 'how', 'should', 'she', 'be', 'treated?'], ['1-', 'Admission', 'for', 'transthoracic', 'ultrasound,', 'assessment', 'by', 'Cardiology', 'and', 'then', 'closed', 'reduction', 'and', 'fixation', 'with', 'plate', 'screw.'], ['2-', 'Admission', 'for', 'evaluation', 'by', 'Nephrology', 'and', 'Cardiology,', 'and', 'then', 'Traumatology', 'will', 'decide', 'whether', 'to', 'use', 'an', 'arthroplasty', 'or', 'a', 'trochanteric', 'nail.'], ['3-', 'Admission', 'to', 'Internal', 'Medicine', '/', 'Geriatrics,', 'progressive', 'stabilization', 'of', 'comorbidities,', 'conservative', 'orthopedic', 'treatment.'], ['4-', 'Closed', 'reduction', 'and', 'fixation', 'of', 'the', 'fracture', 'within', '48', 'hours,', 'very', 'early', 'sedation,', 'orthogeriatric', 'management.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '4'], ['A', 'new', 'approach', 'is', 'currently', 'being', 'developed', 'for', 'the', 'treatment', 'of', 'these', 'patients,', 'which', 'tries', 'to', 'coordinate', 'from', 'the', 'beginning', 'the', 'activity', 'of', 'the', 'different', 'sectors', 'involved,', 'avoiding', 'that', 'the', 'transfer', 'of', 'the', 'patient', 'from', 'one', 'to', 'another', 'takes', 'place', 'at', 'the', 'end', 'of', 'the', 'treatment', 'of', 'each', 'part.'], ['This', 'idea', 'gave', 'rise', 'to', 'the', 'so-called', 'orthogeriatric', 'units",', 'which', 'combine', 'the', "surgeon's", 'surgical', 'activity', 'with', 'that', 'of', 'the', "patient's", 'immediate', 'rehabilitation', 'and', 'the', 'controls', 'and', 'follow-up', 'of', 'internal', 'medicine.'], ['From', 'the', 'very', 'beginning', 'of', 'the', 'process,', 'the', 'social', 'workers', 'and', 'the', 'various', 'vital', 'and', 'support', 'aids', 'are', 'put', 'in', 'place', 'to', 'ensure', 'that', 'recovery', 'is', 'as', 'rapid', 'and', 'complete', 'as', 'possible.', '...'], ['In', 'most', 'cases,', 'surgery', 'should', 'be', 'performed', 'as', 'soon', 'as', 'possible,', 'as', 'soon', 'as', 'the', 'patient', 'is', 'medically', 'stabilized.'], ['There', 'is', 'a', 'contraindication', 'to', 'surgery', 'in', 'patients', 'with', 'unstable', 'medical', 'comorbidity,', 'but', 'several', 'studies', 'have', 'shown', 'that', 'delaying', 'surgery', 'beyond', '48', 'h', 'after', 'admission', 'increases', 'mortality.'], ['This', 'is', 'why', 'the', 'ideal', 'time', 'to', 'intervene', 'in', 'these', 'patients', 'is', 'after', 'achieving', 'stabilization', 'of', 'their', 'medical', 'pathologies,', 'taking', 'care', 'that', 'this', 'takes', 'place', 'before', '48', 'h', 'have', 'elapsed."', 'There', 'is', 'no', 'data', 'to', 'suggest', 'that', 'he', 'has', 'any', 'unstable', 'comorbidity', 'at', 'the', 'present', 'time,', 'so', 'surgery', 'in', 'less', 'than', '48', 'hours', 'and', 'orthogeriatric', 'management', 'is', 'of', 'interest.']]
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378_132
[['QUESTION', 'TYPE:', 'NEUROLOGY'], ['CLINICAL', 'CASE:'], ['A', '72-year-old', 'patient', 'presents', 'with', 'progressive', 'memory', 'loss', 'and', 'word', 'finding', 'difficulty', 'of', 'one', "year's", 'duration.'], ['What', 'is', 'the', 'most', 'useful', 'examination', 'to', 'characterize', 'the', 'type', 'of', 'cognitive', 'deficit', 'he', 'presents', 'with?'], ['1-', 'Neuropsychological', 'evaluation.'], ['2-', 'Brain', 'magnetic', 'resonance', 'imaging.'], ['3-', 'Positron', 'Emission', 'Tomography.'], ['4-', 'Electroencephalogram.'], ['5-', 'nan'], ['CORRECT', 'ANSWER:', '1'], ['The', 'characterization', 'of', 'cognitive', 'deterioration', 'processes', 'is', 'still', 'clinical,', 'with', 'imaging', 'tests', '(MRI', 'or', 'PET)', 'being', 'a', 'support', 'tool', 'in', 'some', 'occasions.'], ['The', 'first', 'option', 'would', 'be', 'the', 'correct', 'one', 'because', 'it', 'allows', 'us', 'to', 'measure', 'in', 'a', 'standardized', 'way', 'each', 'of', 'the', 'cognitive', 'domains,', 'which', 'will', 'allow', 'us', 'to', 'frame', 'the', "patient's", 'deficits', 'in', 'a', 'specific', 'syndrome', 'and', 'to', 'monitor', 'the', 'deterioration', 'with', 'repeated', 'scans', 'over', 'time.']]
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