NR-AR
float64
0
1
NR-AR-LBD
float64
0
1
NR-AhR
float64
0
1
NR-Aromatase
float64
0
1
NR-ER
float64
0
1
NR-ER-LBD
float64
0
1
NR-PPAR-gamma
float64
0
1
SR-ATAD5
float64
0
1
SR-HSE
float64
0
1
SR-MMP
float64
0
1
SR-p53
float64
0
1
mol_id
stringlengths
4
8
smiles
stringlengths
2
322
SR-ARE
float64
0
1
1
1
0
null
0
0
0
0
0
0
0
TOX20750
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
0
1
1
0
null
0
0
0
0
null
null
0
TOX26773
CCCC(=O)O[C@]1(C(=O)COC(C)=O)CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
null
1
1
0
null
1
0
0
0
0
0
0
TOX27429
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)([O-])[O-]
0
1
1
null
null
0
0
0
0
0
0
0
TOX27137
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)([O-])[O-]
0
1
1
null
null
0
null
null
0
null
1
0
TOX28656
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C
null
1
1
null
null
0
0
0
0
0
0
0
TOX384
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
0
1
1
null
null
0
0
0
0
0
0
0
TOX25647
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO
null
1
1
0
null
0
0
0
0
null
0
0
TOX25460
C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)COC(=O)C(C)(C)C
null
1
0
0
null
null
0
0
0
0
0
0
TOX28639
CC(=O)OCC(=O)[C@@]1(O)[C@H](OC(C)=O)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
0
1
1
null
null
0
0
0
0
0
0
0
TOX28524
CCCCC(=O)OCC(=O)[C@H]1[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
0
null
null
null
null
null
null
null
null
0
null
null
TOX31420
CCC(=O)O[C@]1(C(=O)COC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3(F)[C@@H](O)C[C@@]21C
0
1
1
1
null
0
0
0
0
0
0
0
TOX2667
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
0
1
1
null
null
0
0
null
0
null
null
0
TOX25502
CCOC(=O)O[C@]1(C(=O)COC(=O)CC)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
null
1
1
null
null
0
null
null
0
null
1
0
TOX26636
CCC(=O)O[C@]1(C(=O)CCl)[C@@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
null
1
1
0
null
null
0
0
0
0
0
0
TOX26067
C[C@]12C[C@H](O)[C@H]3[C@@H](C[C@H](F)C4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO
0
1
1
null
null
0
0
0
0
null
1
0
TOX28931
C[C@@H]1C[C@H]2C3C[C@H](F)C4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)COC(=O)C(C)(C)C
null
1
1
null
null
null
0
0
null
null
0
0
TOX28890
C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)COC(=O)CCC(=O)O
null
1
1
0
null
1
0
0
0
0
0
0
TOX20742
C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
0
1
1
0
null
0
0
0
0
0
0
0
TOX3300
C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
0
1
1
0
null
1
0
0
0
null
0
0
TOX3302
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
null
1
1
0
null
null
0
0
0
null
0
0
TOX3303
C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)COC(=O)CCC(=O)[O-])[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
null
1
1
null
null
0
0
0
0
0
0
0
TOX25306
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
0
1
1
0
null
0
0
0
null
0
0
0
TOX25365
C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
0
1
1
0
null
0
0
0
0
0
null
0
TOX27435
CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
0
1
1
null
null
null
0
0
0
0
1
0
TOX25646
CC(=O)OCC(=O)[C@@]1(OC(C)=O)[C@@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
0
1
1
0
null
0
0
0
0
0
null
0
TOX26460
C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C(Cl)=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
0
1
0
null
null
null
null
0
0
0
0
null
TOX25474
COC(=O)[C@@]1(C)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
1
1
1
0
null
1
1
0
0
0
0
null
TOX3276
C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O
1
null
null
null
null
null
null
null
null
0
null
null
TOX31414
CC(C)=CCC/C(C)=C/CC/C(C)=C/C(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
null
null
null
null
null
null
null
null
null
0
null
null
TOX26468
CCOC(=O)O[C@]1(C(=O)OCCl)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
1
1
1
1
null
0
0
0
0
0
1
0
TOX25907
CCC(=O)O[C@]1(C(=O)CCl)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
null
1
1
null
null
null
0
null
0
0
1
0
TOX2673
CCCCC(=O)O[C@]1(C(=O)CO)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
null
1
1
null
null
0
0
null
0
null
1
0
TOX2671
CCCC(=O)O[C@]1(C(=O)COC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
null
1
1
null
null
0
0
0
0
null
0
0
TOX3422
CC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
null
1
1
0
null
0
0
0
0
0
0
0
TOX1184
C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO
0
1
0
null
null
0
0
0
0
0
1
0
TOX25511
CCC(=O)O[C@]1(C(=O)SCF)[C@H](C)C[C@H]2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
0
0
0
0
0
0
0
0
0
0
0
0
TOX161
c1ccc(-c2ccccc2)cc1
0
0
null
null
null
0
0
0
0
0
null
0
TOX3043
O=C(O)CCC(=O)c1ccc(-c2ccccc2)cc1
0
0
0
1
1
0
0
0
1
0
1
0
TOX137
Nc1ccc(-c2ccc(N)cc2)cc1
1
0
0
0
0
null
0
null
0
0
0
0
TOX10189
Nc1ccccc1-c1ccccc1
0
0
0
0
0
0
null
0
0
0
null
0
TOX3883
Clc1cccc(-c2cc(Cl)cc(Cl)c2)c1
0
0
0
1
0
0
1
0
1
0
0
0
TOX511
Cc1cc(-c2ccc(N)c(C)c2)ccc1N
1
0
0
0
0
0
0
0
0
0
0
0
TOX27177
Cc1ccc(-c2ccccc2)cc1
0
0
0
1
null
1
0
0
0
0
0
0
TOX72
Nc1ccc(-c2ccccc2)cc1
1
null
null
null
null
null
null
null
null
0
null
null
TOX31569
C#Cc1ccc(-c2ccccc2F)cc1
0
0
0
0
0
0
0
0
0
0
1
0
TOX5404
CCCCCCc1ccc(-c2ccc(C#N)cc2)cc1
0
0
0
0
0
null
0
0
0
0
0
0
TOX5746
O=[N+]([O-])c1ccccc1-c1ccccc1
0
0
0
0
null
1
1
0
1
0
null
0
TOX1152
Oc1ccc(-c2ccccc2)cc1
1
0
0
0
0
0
0
0
0
0
1
0
TOX1151
Oc1ccccc1-c1ccccc1
0
0
0
0
0
0
0
0
0
0
null
0
TOX12180
Clc1cc(Cl)c(-c2cc(Cl)c(Cl)cc2Cl)cc1Cl
0
0
0
1
0
0
0
0
0
0
null
0
TOX1174
Brc1cc(-c2ccc(Br)c(Br)c2Br)cc(Br)c1Br
0
0
0
1
0
null
0
null
null
0
null
0
TOX12525
COc1ccc(-c2ccccc2)cc1NNC(=O)OC(C)C
1
0
0
0
0
0
0
0
1
0
1
0
TOX5091
COc1cc(-c2ccc(N)c(OC)c2)ccc1N
1
0
0
0
0
0
0
0
0
0
0
0
TOX4640
Brc1ccc(-c2ccccc2)cc1
0
0
0
0
0
0
0
0
0
0
0
0
TOX27728
Fc1ccccc1-c1ccccc1
0
0
0
1
0
0
0
0
0
0
null
0
TOX6120
Cc1cc(-c2cc(C)c(N)c(C)c2)cc(C)c1N
0
0
0
1
0
0
0
0
0
0
0
0
TOX484
COc1cc(-c2ccc(N=C=O)c(OC)c2)ccc1N=C=O
0
0
0
0
null
1
1
0
0
0
1
null
TOX24533
Clc1ccccc1-c1ccccc1Cl
0
0
null
1
1
null
0
null
1
1
1
1
TOX1314
Nc1cc(Cl)c(-c2cc(Cl)c(N)cc2Cl)cc1Cl
1
0
0
1
1
0
0
0
0
null
1
0
TOX1312
Nc1ccc(-c2ccc(N)c(N)c2)cc1N
1
0
0
0
null
1
1
null
1
0
1
1
TOX9120
Oc1ccc(-c2ccc(O)cc2)cc1
1
0
0
0
0
1
0
null
0
0
0
0
TOX17231
CC(C(=O)O)c1ccc(-c2ccccc2)c(F)c1
0
0
0
null
0
0
0
1
0
null
0
0
TOX26160
CCOC(=O)Cc1ccc(-c2ccccc2)cc1
null
0
0
0
0
0
0
0
0
0
null
0
TOX26081
Cc1cc(OI)c(C(C)C)cc1-c1cc(C(C)C)c(OI)cc1C
0
0
null
0
0
0
0
null
0
0
null
0
TOX2932
O=C(O)c1cc(-c2ccc(F)cc2F)ccc1O
null
1
0
1
1
1
1
0
1
null
null
1
TOX433
Nc1ccc(-c2ccc(N)c(Cl)c2)cc1Cl
1
0
0
1
null
1
0
0
null
0
null
0
TOX631
Nc1ccc(-c2ccc(F)cc2)cc1
null
null
0
0
null
null
0
0
0
0
null
0
TOX4639
Brc1cccc(-c2ccccc2)c1
0
0
0
0
0
0
0
0
0
0
0
0
TOX4638
Brc1ccccc1-c1ccccc1
0
0
0
0
0
0
0
1
0
0
0
0
TOX25389
O=C(O)Cc1ccc(-c2ccccc2)cc1
0
null
null
null
null
null
null
null
null
0
null
null
TOX31412
Cc1ccc(-c2ccccc2C#N)cc1
0
0
0
0
0
0
0
0
0
0
null
0
TOX28168
CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)cc2)cc1
0
0
0
null
0
0
0
1
0
0
0
0
TOX26565
O=C(O)c1ccccc1-c1ccc(C(F)(F)F)cc1
0
0
0
1
0
0
0
0
0
0
1
0
TOX20794
[O-]c1ccccc1-c1ccccc1
1
1
0
null
0
1
null
0
0
0
1
null
TOX2353
Oc1ccc(-c2ccccc2)c(Cl)c1
1
0
0
0
0
0
0
0
0
0
0
0
TOX28526
CC(=O)OC(C)OC(=O)C(C)c1ccc(-c2ccccc2)c(F)c1
0
0
0
0
0
0
0
0
0
0
0
0
TOX27072
CC1=CC(O)CC(C)(C)C1
0
0
0
0
0
null
0
0
0
0
0
0
TOX27078
C=C(C)[C@@H]1CC=C(C)CC1
0
0
0
0
0
0
0
0
0
0
0
0
TOX27088
CC1=C(CC=O)C(C)(C)CCC1
0
0
0
0
0
0
0
0
0
0
0
0
TOX1769
CC(=O)/C=C/C1=C(C)CCCC1(C)C
0
0
0
0
0
0
0
0
0
0
0
0
TOX6240
CCC(=O)/C=C/C1C(C)=CCCC1(C)C
0
0
0
0
0
0
0
0
0
0
0
0
TOX27142
CC1=C(C=O)C(C)(C)CCC1
0
0
0
0
0
1
0
0
0
0
null
0
TOX7970
CC(C)(O)CCCC1=CCC(C=O)CC1
null
0
0
0
0
0
0
0
0
0
0
0
TOX27952
CC(=O)C=CC1=C(C)CCCC1(C)C
0
0
0
0
0
null
0
0
0
0
0
0
TOX24833
CCC(=O)OC(C)(C)C1CC=C(C)CC1
0
0
0
0
0
null
0
0
0
0
0
0
TOX15160
CC(=O)/C=C/C1C(C)=CCCC1(C)C
0
0
0
0
0
0
0
0
0
0
0
0
TOX27422
CCC(=O)C1CC(C(C)C)CC=C1C
0
0
0
null
null
0
0
0
0
0
0
0
TOX24600
OCC1CC=CCC1
0
0
0
0
0
1
0
0
0
0
0
0
TOX6496
CC(=O)OC(C)(C)C1CC=C(C)CC1
0
0
0
0
null
null
0
1
0
0
null
0
TOX20404
CC1=C(/C=C/C(C)=C\C=C/C(C)=C/C(=O)O)C(C)(C)CCC1
null
0
0
0
0
0
0
0
0
null
0
0
TOX25954
CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
null
0
null
0
0
0
0
0
0
0
0
0
TOX7047
CC(=O)/C(C)=C/C1C(C)=CCCC1(C)C
0
0
0
0
null
0
0
0
0
0
null
0
TOX22094
CC(C)=CCC[C@](C)(O)[C@@H]1CC=C(C)CC1
0
0
null
0
null
null
1
null
null
null
null
null
TOX5998
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=O)C(C)(C)CCC1
null
0
0
0
1
0
1
null
0
null
1
null
TOX5997
CC1=C(/C=C/C(C)=C/C=C/C(C)=C\C=O)C(C)(C)CCC1
null
0
0
0
0
0
0
0
0
0
0
0
TOX27042
CC(=O)/C=C/C1C(C)=CCC(C)C1(C)C
0
0
0
0
0
0
0
0
0
0
0
0
TOX21190
C=C(C)[C@@H]1CC=C(C=O)CC1
null
0
0
0
0
null
0
0
0
0
0
0
TOX24574
CC1=CC(C)C(C=O)CC1
0
0
0
0
0
0
0
0
0
0
0
0
TOX4738
C=C(C)C1CC=C(C)C(OC(C)=O)C1
0
0
0
0
0
0
0
0
0
0
0
0
TOX4736
C=C(C)C1CC=C(C)C(O)C1
0