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What is structural genomics?
Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and modeling approaches. The principal difference between structural genomics and traditional structural prediction is that structural genomics attempts to determine the structure of every protein encoded by the genome, rather than focusing on one particular protein. With full-genome sequences available, structure prediction can be done more quickly through a combination of experimental and modeling approaches, especially because the availability of large number of sequenced genomes and previously solved protein structures allows scientists to model protein structure on the structures of previously solved homologs.
Because protein structure is closely linked with protein function, the structural genomics has the potential to inform knowledge of protein function. In addition to elucidating protein functions, structural genomics can be used to identify novel protein folds and potential targets for drug discovery. Structural genomics involves taking a large number of approaches to structure determination, including experimental methods using genomic sequences or modeling-based approaches based on sequence or structural homology to a protein of known structure or based on chemical and physical principles for a protein with no homology to any known structure.
As opposed to traditional structural biology, the determination of a protein structure through a structural genomics effort often (but not always) comes before anything is known regarding the protein function. This raises new challenges in structural bioinformatics, i.e. determining protein function from its 3D structure.
Structural genomics emphasizes high throughput determination of protein structures. This is performed in dedicated centers of structural genomics.
While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. On the other hand, the scientific value of some resultant structures is at times questioned. A Science article from January 2006 analyzes the structural genomics field.
One advantage of structural genomics, such as the Protein Structure Initiative, is that the scientific community gets immediate access to new structures, as well as to reagents such as clones and protein. A disadvantage is that many of these structures are of proteins of unknown function and do not have corresponding publications. This requires new ways of communicating this structural information to the broader research community. The Bioinformatics core of the Joint center for structural genomics (JCSG) has recently developed a wiki-based approach namely Open protein structure annotation network (TOPSAN) for annotating protein structures emerging from high-throughput structural genomics centers. |
Make a list of some popular Japanese animations, I haven't watched yet.
Here are a list of some popular Japanese animations: Death Note, Pokémon, Re:Zero -Starting Life in Another World-, JoJo’s Bizarre Adventure, Neon Genesis Evangelion, Fullmetal Alchemist, One Piece, Clannad, Naruto, and Demon Slayer: Kimetsu no Yaiba. |
Why is March Madness so popular in the United States?
March Madness is an annual college basketball tournament played in March. It consists of 68 teams that play in a single elimination tournament until a winner is determined. There are both men's and women's tournaments, though the men's tournament has been taking place for longer, since 1939. Interestingly, the first tournament had only 8 teams.
The tournament is popular with basketball fans and non-fans alike. Some people enjoy the tournament because their college or university's team is participating in the tournament. Other fans enjoy the unpredictability of the results and cheer for a team that they adopt for the tournament. Many people enjoy rooting for an underdog; a team that is ranked lower overall but can gain a lot of attention by winning against teams ranked higher. This is one reason it is called 'March Madness.' |
Based on this paragraph about San Diego, what is the largest city in the state of california?
Los Angeles |
Given this reference text about Gorbachev, tell me whether he was an ally of Yeltsin and Putin.
According to this passage, Gorbachev was neither an ally of Yeltsin nor of Putin. In fact, he was a vocal critic of both of them. |
Which of these famous football players have never won the Balon D'Or: Messi, Xavi, Zidane, Ronaldinho, Iniesta, Neymar
From the list of players provided the ones that have never won the Balon D'Or are Xavi, Iniesta and Neymar. All the other players in the list have won the Balon D'Or at least one time |
From the passage provided, extract the names of the writers for the movie Captain America: The First Avenger. Separate them with a comma.
Christopher Markus, Stephen McFeely |
Give me a list of 3 hobbies that are good for your health and inexpensive
1. Long-distance running - Long-distance running is good for heart health and also mental health.
2. Hiking - Going for a hike can be a great way to clear your head and improve your fitness. Hiking is almost always free, but some parks can have an entry fee.
3. Walking - Not only is walking good for your heart, it can also help you to manage stress |
Which of these words are nouns and which are adjectives. Fridge, wipe, bed, chair, jump, yell, sleep, fruit and talk.
Fridge, bed, chair and fruit are words that are nouns. Wipe, jump, yell, sleep and talk are words that are adjectives. |
What is Bart Simpson's graffiti tag?
El Barto |
What is the difference between walking and running?
Walking and running involves taking steps to gain velocity, typically on land. The differences come in terms of speed. Walking happens at a slower pace and pace than running. One that traverses longer distances at a faster rate when running versus walking. |
What is the happiness index report and which country tops the happiness index in the world
United nations every year in collaboration with sustainable development solution network perform survey and release the report global happiness index. As of March 2023, Finland has been ranked the happiest country in the world six times in a row.
The World Happiness Report is a publication that contains articles and rankings of national happiness, based on respondent ratings of their own lives, which the report also correlates with various (quality of) life factors |
Abel Prize is given in which field ?
Abel Prize is given in the field of Mathematics |
How many people who contract COVID-19 end up experiencing symptoms and what symptoms might they experience?
Approximately two-thirds of people who are infected with COVID-19 develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock, or multiorgan dysfunction). |
What is surfing?
Surfing is a sport where a rider uses a surfboard to ride a wave |
Tell me the genre of each of the following books, choosing between science fiction, fantasy, or neither.
The Name of the Wind by Patrick Rothfuss, The Player of Games by Iain M. Banks, Crying in H Mart by Michelle Zauner, Crime and Punishment by Fyodr Dostoevsky, and Hyperion by Dan Simmons.
The Player of Games and Hyperion are science fiction, The Name of the Wind is fantasy, and both Crying in H Mart and Crime and Punishment are neither of those genres. |
Short Summary about 2011 Cricket World Cup
- 2011 Cricket World Cup was played in India, Sri Lanka and Bangladesh
- India won the tournament defeating Sri Lanka.
- Yuvraj Singh was declared the Man of the Tournament
- Opening Ceremony was held on 17 February 2011 at Dhaka |
Who were Fernando Pessoa's main heteronyms?
Fernando Pessoa created approximately seventy-five heteronyms, of which three stand out, Alberto Caeiro, Álvaro de Campos, and Ricardo Reis.
Pessoa's heteronyms differ from pen names, because they possess distinct biographies, temperaments, philosophies, appearances, writing styles and even signatures. |
Why are cats better than dogs in some people's opinion?
There are couple of reasons that people would prefer cats over dogs. The major one is that cats are lower maintenance than dogs. Most cats are happy indoors and doesn't need walks daily. This becomes a huge advantages as many younger generation people prefers more indoor activities today as well. There are couple other advances: 1. Cats are less likely to cause a true mess of your house than dogs due to their smaller size and weaker strength. 2. Cats are less smelly than dogs. 3. Cats are quieter than dogs as they don't bark or howl. |
Given a reference text that describes the air travel disruption after the 2010 Eyjafjallajökull eruption, how long was the air travel over Europe disrupted for?
Initially there was an uninterrupted shutdown of the air travel from April 15 until April 23. There were intermittent disruptions in different parts of Europe in the following weeks until May 17. Overall, the air travel over Europe disrupted for 33 days between April 15 and May 17 2010. |
Given the reference text about moths, what family does Bityla sericea belong to?
Noctuidae |
Identify which instrument is string or percussion: Tan-tan, Ruan
Ruan is string, Tan-tan is percussion. |
In which European city would you find Orly airport?
Paris. |
Classify each as National Park in Utah or Arizona: Zion National Park, Bryce Canyon, Grand Canyon, Saguaro National Park
National Parks in Utah: Zion National Park, Bryce Canyon
National Parks in Arizona: Grand Canyon, Saguaro National Park |
How to prepare without baking dessert recipe -Banana Pudding?
Take a casserole mold. Layer the mold's base with cookies of your choice. Slice up 1½ - 2 bananas and layer them above the cookies. The pudding mixture can be made by following the instructions on the box. Mix the tub of Cool Whip well before pouring it above the pudding mixture. Pour half of the pudding mix on the first layer of bananas and cookies. Add more bananas and cookies, followed by more pudding mixture. Repeat the process to add more layers. Use cookie crumbs and sprinkle on top. Refrigerate until serving. |
Write a short story about a cat named Bistro that is full of adventure.
Bistro patiently waited outside his backdoor in the early afternoon. The clouds were starting to clear, revealing the first full sunlight of what had been a dreary spring day in Seattle. As Bistro sat pondering his afternoon plans, he saw something red out of the corner of his eye! a small brown dog with a red collar was sprinting down the alley!
Unable to resist, Bistro leapt to his feet and immediately gave chase. They bounded along together, with Bistro slowly closing the gap. They ran through the neighborhood park, narrowly avoiding the large black lab that plays on the baseball field. After 10 blocks, the small brown dog came to a quick halt. It wagged it's tail and waited patiently outside the front door of a blue house. The owner of the house opened the door, letting both Bistro and the dog inside. Bistro quickly realized he had made a mistake! The dog lived there and now he was far from home and didn't know his way back.
The next morning, the dog and its owner went for a walk around the neighborhood. They were able to find Bistro family and brought it home safely immediately. Hooray for Bistro! |
what is elasticsearch?
Elasticsearch is a search engine based on the Lucene library. It provides a distributed, multitenant-capable full-text search engine with an HTTP web interface and schema-free JSON documents. |
Extract the names of all schools in the text
Amherst College
Yale College
Washington University |
Tell me which of the following circumstances warrant calling 911: fridge runs out of food, micro kitchen runs out of slacks, someone gets hit by a car, a child is drowning in a public pool, your saving account runs out of money, someone carries assault weapons into campus.
Given the listed circumstances, you should call 911 immediately when someone gets hit by a car, when a child is drowning in a public pool, or you see someone carrying assault weapons on campus. |
What would cause stride scheduling to cause inefficiency in CPU operations?
Blocking operations would cause dependency issues between p1 and p2 if either is blocking the other. |
What are some of the popular monuments in India?
Some of the popular monuments in India are:
Taj Mahal : The Taj Mahal is a white marble mausoleum commissioned by Shah Jahan, the fifth Mughal Emperor, in 1631. It was built in memory of, and to house the tomb of his wife, Mumtaz Mahal. It is located on the right bank of the Yamuna River in a vast Mughal garden that encompasses nearly 17 hectares, in the Agra District in Uttar Pradesh.
Qutab Minar : The Qutab Minar is a 72.5m tall red sandstone tower located in the south of Delhi. The Minar is surrounded by a complex of gardens, mosques and other buildings like one of the Ashoka pillars. |
Identify which instrument is string or percussion: Whip, Waldzither
Waldzither is string, Whip is percussion. |
Given this paragraph about Yahalom and his works, tell me when he was born?
Based off of this paragraph, it is clear that Yahalom wrote books and articles "from Byzantine Palestine (5th century CE) to the early modern period". Therefore, it is likely that Yahalom was born in the early modern period or sometime after the early modern period.
The exact date of Yahalom's birth cannot be determined given the provided information. |
Is the sum of an even number and an odd number even or odd?
It's an odd number. |
What are some good places to go on a surf trip?
Some favorite spots for a surf trip include:
-Hawaii
-Southern California
-Baja California
-Bali, Indonesia,
-Tamarindo, Costa Rica
-Sydney, Australia |
Who is the best soccer player in the world?
The best player in the world as of 2023 is Lionel Messi. He is also widely regarded as the greatest player to ever grace the game. |
Write a rap about work
Hard work they say it always pays off
But I think that smart work is the way to go
It starts by finding and pursuing your passion
The money will follow you'll have plenty of cash then
This ain't gonna happen overnight
You've gotta hustle with grit to do it right
Surround yourself with the best achievers
Keep your mind right don't stop believing
You'll hit bumps in the road as you go on your journey
So you gotta set goals and you gotta keep learning
It's true there's more to life than your career
So keep your eye on the prize keep your vision clear
Because all the early mornings and all the late nights
They will fly by without warning so enjoy the great ride |
From the passage provided, extract the difference in caffeine between a light roast and a dark roast.
The difference of caffeine content between a light roast and a dark roast is about 0.1%. |
What are some low fat snack options?
popcorn, watermelon, low fat cheese sticks, low fat cottage cheese, apples, grapes, carrots, sugar snap peas, edamame |
Behind Delta tables is the data stored in Parquet file formats?
Yes, they are parquet. Delta API is a protocol and the layer manages the individual parquet files as if they were a larger table. If BQ can consume from the Delta protocol it could work but I would not suggest reading the files inside of a Delta table as just a parquet table - there would likely be too many stale files |
Is there any river that doesn’t meet a sea?
There are several, in fact! The most famous example would be the Okavango River, which - instead of reaching the ocean - peters out into the massive Okavango Delta and evaporates, in the middle of the Kalahari Desert. Some other notable instances include the Onyx River - the longest river in Antarctica, at 32 kilometres in length - which simply flows from one lake to another. And the Omo River, which starts in the Ethiopian Highlands and ends in Lake Turkana, Kenya. But these last two flow into lakes. That’s not unusual for a river, right?
Certainly not; however, in the vast majority of cases, the river’s water will meet the sea eventually, as almost all lakes are drained by other rivers which reach the ocean. Not so for these lakes. Why? Because they’re in what are known as endorheic basins. In hydrology, a basin is a region in which all precipitation will drain and collect into a common outlet. There are innumerable river basins throughout the world, with dozens in the (contiguous) US alone. If you look closely at the US map, you might notice that not all these river basins enter the sea. They are endorheic basins; closed, self-contained systems where the amount of water flowing in is equal to the amount which evaporates or seeps away.
You can theoretically find them in any climate, but they tend to be in very dry areas - e.g. the Kalahari - as where it’s rainier erosion will usually carve pathways to the ocean. They also often have mountains or glaciers blocking their way to the sea. Endorheic basins make up about 18 per cent of the world’s land area - although this map doesn’t show the ones in Antarctica.
Also note that 6 of the world’s 25 largest lakes are in endorheic basins - Lakes Turkana, Balkhash, Titicaca, Issyk-kul, and Urmia, and of course the Caspian Sea - the largest lake in all the world. |
What does Midnight Sun mean?
Midnight sun is a natural phenomenon that occurs in the summer months in places north of the Arctic Circle or south of the Antarctic Circle, when the Sun remains visible at the local midnight. |
How long is a marathon?
A marathon is 26.2 miles and 42.195 kilometers |
Tell if these are grown in trees or bushes: apples, strawberries, bananas, pineapples, coconut, raspberries, blueberries.
Apples: trees, strawberries: bushes, bananas: trees, pineapples: bushes, coconuts: trees, raspberries: bushes, blueberries: bushes. |
What are a couple of simple tricks to make a simple wood carving look more polished and professional?
Okay the first obvious point to make here is that the thing that will make any piece of art - including a wood carving - look more professional is the quality of the art! That means the skill and the artistic quality that goes into it, specifically. But there are a couple things you can do to dress it up a bit - think about your school days and sliding that english paper into a fresh new folder with a carefully penned title on the front. So back to wood carving. What can you do? Let's say you've carved yourself a nice salmon complete with fens and gill lines. Well here are three ways to dress it up. First and most obvious - paint it. You can go for detail paint or you can use more of a water color approach that will give the wood a colored wash. The sky is really the limit here. Second, you mount it on a stand so it floats about the ground. Drill a small whole in the bottom of the fish, do the same in a wood block you've sanded up and you have s stand. Third and a bit more out there - consider if there are simple additions you can add. I made an angler fish and used a drive flower with stem as the attached antenna. Look around and think about what you can add to your project. Last and most basic, put a coat of varnish on it to seal it up - and if you choose give it a bit of shine. All these ideas will give a little bit of extra finish and pop to your project. |
Is Dirty picture a movie?
Yes. The Dirty Picture is a 2011 Indian Hindi-language biographical musical drama film inspired by the life of Silk Smitha, an Indian actress. It is a real life story. |
Extract all of the dates mentioned in this paragraph and list them using bullets in the format {Date} - {Description}
• January 21, 1968 - This is when Ilya Smirin was born
• 1990 - This is when Ilya Smirin was awarded the title of Grandmaster by FIDE |
List down the key takeaways from the below paragraph on how Singapore growth is derived from its monetary policy
Policy to adopt foreign exchange mechanism instead of interest rates to regulate monetary system
It manages Singapore dollar against multiple currency.
it policy review/change is less than other central banks
Singapore dollar nominal effective exchange rate (S$ NEER). |
Who is the greatest basketball player of all time?
While this question continues to be debated by sports fans and pundits around the globe nearly every single day, usually the answer comes down to one of a handful of players: Michael Jordan, Kareem Abdul-Jabbar, LeBron James, or Bill Russell.
Michael Jordan is the most common answer to this question. He won 6 championship rings, 5 MVP's and never lost an NBA Finals series. If he didn't take a two year hiatus from the NBA to play baseball, there is a good chance that he would have won 8 NBA championships in a row. Michael was a fantastic defender, and arguably the most relentless competitor that the NBA has ever seen. He was notorious for gambling on almost anything, and his iconic Air Jordan shoe is largely responsible for Nike's success as a global brand.
Kareem Abdul-Jabbar was, until recently, the NBA's all time leading scorer. He played 20 seasons in the NBA, was a 19-time All-Star, 6-time MVP, and a 6-time NBA champion. He was incredibly consistent throughout his entire career, and transcended the NBA as a civil rights activist, author and even an actor.
LeBron James is the greatest NBA player of this generation. He is a five-time NBA champion, four-time MVP, and recently surpassed Kareem Abdul-Jabbar as the NBA's all time leading scorer. No player came in to the NBA with greater expectations, and somehow, LeBron surpassed them all. LeBron first made headlines at age 15, and many of his high school games were nationally televised.
Bill Russell was the ultimate teammate. In 13 seasons in the NBA he won 11 titles, all as a member of the Boston Celtics. During his last two seasons, he won the title as a Player/Coach, also becoming the first black coach to win an NBA title. Russell was a five-time MVP and 12-time NBA All Star, and is widely respected as the best defensive player of his era. He had a well-publicized rivalry with Wilt Chamberlain, but while Wilt chased stats, Bill made sure his team won.
In addition to these four, there have been many other amazing basketball players over the years, including modern stars like Stephen Curry, Kevin Durant, the late Kobe Bryant, Magic Johnson, Larry Bird and more. Debating who is the best player ever is part of what makes basketball so entertaining. So while most people may say that Michael Jordan is the greatest player ever, this debate will rage on for years to come as more and more stars enter the league and build their careers. |
Provide three bullets about Einstein from this paragraph that does not relate to physics
- Einstein was born in Germany
- Einstein lived to 76 years old
- One part of Einstein’s legacy was that his name became synonymous with “genius” |
Who was the original singer of Static-X?
The original singer of metal band, Static-X, was Wayne Static. |
What medicinal plants should I grow in my Mid-Atlantic garden?
Echinacea
Elder
Bee balm
Lemon balm
Mullein
Burdock
Yarrow
Wood Betony |
Where did Alexander Digeon fought
Alexander Elisabeth Michel vicomte Digeon, (27 June 1771 – 2 August 1826) fought in the French Revolutionary Wars in the cavalry. He became a general officer during the Napoleonic Wars, fighting in a number of important battles. After 1814, he gave his loyalty to the Bourbon Restoration and briefly served as Minister of War. |
Identify which instrument is string or percussion: Tassa, Sitar
Sitar is string, Tassa is percussion. |
Does Amazon use doors for desks?
Jeff Bezos initially used doors purchased from the local hardware store and added legs, and door desk was born. He did that because funds were limited, and this was the least expensive way for him to purchase a desk. Today, Amazon still uses wooden doors with four pieces of wood attached for legs. New employees receive directions to calculate the optimum desk height, then fill out a form, and maintenance cuts the wooden legs to achieve the correct size. The company does provide adjustable desks by request only. |
How many world championships has Max Verstappen won?
Max Verstappen has won 2 Formula One World Championships. He won his first one in 2021 at the Abu Dhabi Grand Prix. In 2022 he won his second consecutive Formula One championship
As of the 3rd race of the 2023 season, he is leading the World Championship with 69 points. |
What is the difference between solar power and hydrogen fuel cell? What are the advantages of hydrogen?
Solar captures the harvesting of the sun while hydrogen is the osmosis process of extracting the hydrogen cells to create energy. Hydrogen allows for a more consistent energy source while also enabling higher load generation over solar. |
Why is selling stocks short a high risk investment technique
Short selling stocks is a high risk technique as you are betting that a stock will go down in value and the downside risk is essentially unlimited. When you buy a stock "long" you know the stock can "only" go to (0) so your risk is what you invested, when you are selling a stock "short" the stock has no limit to far it can go up and therefore how much money you can lose. |
Is there a movie about Wikipedia
Yes. Truth in Numbers? Everything, According to Wikipedia is a 2010 American documentary film that explores the history and cultural implications of the online, editable encyclopedia Wikipedia. The film considers the question of whether all individuals or just experts should be tasked with editing an encyclopedia. |
Extract all the dates from this paragraph provided.
1973, 1974, 1979, 1983 |
In which cities was the AFL Grand Final played during COVID-19 ?
The AFL Grand Final was played in Brisbane in 2020 and Perth in 2021 due to the COVID-19 pandemic. Usually the AFL Grand Final is played in Melbourne, Victoria. |
Why do people like to live in Minnesota?
Minnesota is a great place to live for a multitude of reasons. While the winter weather can be difficult, the overall high quality of life people from Minnesota have heavily outweighs this perceived negative. Minnesota’s education system is consistently rated of one of the best in the United States. Standardize test scores reflect this as well as a strong college/university ecosystem. Minnesota is home to a diverse set of companies and has a higher-than-normal number of F500 companies headquartered in Minnesota. The presence of a large, diverse set of companies has provided Minnesotans with one of the lowest employment rates in the USA. Minnesota is also highly rated when it comes to restaurants based on the number (on a per capita basis) of James Beard Award winners. The overall healthcare systems (including the famous Mayo Clinic) rank very high nationally. |
What are the most expensive cities in the world ?
This is an exhaustive list of the most expensive cities : Singapore, Tel Aviv, New York, Hong Kong, Los Angeles, Zurich, Geneva, San Francisco, Paris and Sydney |
Identify which instrument is string or percussion: Tap shoe, Sarod
Sarod is string, Tap shoe is percussion. |
Tell me which of the following countries as considered SAARC countries: Afghanistan, Bangladesh, Bhutan, India, United States of America, United Kingdom, China, Singapore
Afghanistan, Bangladesh, Bhutan and India are part of the SAARC eight member countries. United States of America, United Kingdom, China and Singapore are not affiliated to SAARC countries. |
What are the 9 locations of Dick's Drive In restaurants?
The nine locations, once the final location is completed in 2023, are as follows: Wallingford, Seattle; Capitol Hill, Seattle; Crown Hill, Seattle; Queen Anne, Seattle; Edmonds; Kent; Bellevue; and Federal Way. |
Where is a good place to go on holiday in Cornwall, England?
Without a doubt, the best place in Cornwall is Rock. Situated in close proximity to both Daymer Bay and Polzeath beach, you have easy access to great beaches and breathtaking clliff top walks. In addition, the Camel estuary is close by which is great for dinghy sailing and there is a frequent water taxi that will take you over the estuary from Rock to Padstow (which is full of good pubs and restaurants).
If one is partial golf, St Enedoc's golf course can be found in Rock which boasts one of the most beautiful Links in the South West. On the Links one will find St Enedoc's Church, an enigmatic church sunken into the dunes and also the burial place of Sir John Betjeman CBE, who was Poet Laureate from 1972 until his death on 19 May 1984. |
When did Uber IPO?
Uber went public on May 9, 2019 |
Classify the below aircraft models based on the companies which created them.
Next-Generation 737, A220, 737 MAX, A350, A330, 747-8, 767, A320, 777, 777X, A380, 787
Boeing- Next-Generation 737, 737 MAX, 747-8, 767, 777, 777X, 787
Airbus- A220, A320, A330, A350, A380 |
Extract some details about the company 'Bath & Body Works' from the given passage
1. In 1990, New Albany, Ohio, Bath & Body Works was founded.
2. In the same year Sept 1990 , the company's first store was opened in a Cambridge, Massachusetts mall.
3. In year 1997, a secondary brand called Bath & Body Works at Home was also launched.
4. Two years after the lauch, they launched another company named the White Barn Candle Company, a division specializing in the sale of scented candles. |
Who was the last king of the Reach before Aegon's Conquest?
Mern IX Gardener was the last king of the Reach. When the last of the Gardener's lineage died, the house went extinct and the Reach was assigned to House Tyrell to rule. |
If you were the last person on Earth, what thoughts would you leave behind in a diary if future life were to find it?
I sit here today writing this diary entry as the last person on Earth. It is a feeling like no other and I can say, never in a million years would I have believed this to be a distinction bestowed upon me. But, here I am... just me and Mother Earth. Idle time is not my friend so I try to stay busy. Today, I am busy reflecting upon my 56 years on Earth and lessons learned. Not just lessons I learned from my personal experience, but what I believe are lessons learned for all mankind. The lessons are clear. And all of the lessons are simple practices that I feel we have drifted away from in our modern day. If I had to summarize all of my learnings into one statement it would read like this... "Live simply, love, find faith/hope in a higher source, move every day, work hard on relationships and building communities (real and face to face), find time to rest and creating space and be thankful." That's it! As I said, the lessons are clear. I would like to think that life on Earth will somehow, someway start again and someone will find this diary. And, if that happens, then maybe, just maybe, another human race can benefit from my feelings on life and "living". |
are new year resolutions effective?
To answer the question, let us look at some statistics from public surveys about new year's resolutions. In 2022 about 46% of all people who made resolutions achieved their goals by the end of the year, 11% kept their resolutions for at least 6 months, 14% lasted at least 3 months, 19% lasted for a month, and 11% quit within a month. To make resolutions more effective, not only make the statement of what you want to change, but also list the steps you take to achieve it, and when you want to achieve it. Here are a few tips: Mentally prepare for change; Set goals that resonate with you; Limit resolutions to a manageable amount; Make resolutions specific, measurable, and time-sensitive; Break big goals up into smaller chunks; Write resolutions down; Automate things to keep tabs on yourself; Remember you can always get back on even if you fall off the track! |
Hugh Lofting created which famous character
Doctor Dolittle |
What are the different kinds of rock climbing?
The most popular types of climbing are:
- Bouldering: climbing low hanging challenges, likely with crash pads to fall on.
- Sport climbing (or indoor climbing): Climbing a route with fixed anchors
- Traditional climbing: Climbing with gear that is inserted and removed without fixed anchors
Once climbers gain experience, they are able to begin climbing more extreme outdoor terrain however many climbers may stick to bouldering or sport climbing. |
How do I choose a new phone?
There are many options when choosing a new smartphone. Many boil down to personal preference, but you should always look at your own personal needs and weigh those against the pros and cons of each phone. Some of the main things that people look for when choosing a new phone are:
- Price
- Camera Quality
- Battery Life
- Ease of Use
- Speed
- Connectivity (WiFi, Bluetooth, and Cellular Data)
Some other things to consider are the ecosystem of services you may already use (e.g. Apple ID or Google accounts), and how long you expect to need to use the device for (longevity). In general, more expensive mobile hardware will last longer than lest costly devices. |
Classify the below car manufacturing companies based on their countries of origin.
Mazda, KIA, Hyundai, Ford, Honda, Toyota, Chevrolet
Japan - Toyota, Mazda
Korea - South Korea
USA - Chevrolet, Ford |
What is a world war and how many world wars have happened so far?
World war is an international conflict that involves most major countries. There have been 2 world wars so far. |
What is the name of the first dog that went to space?
Laika |
Which nation placed its astronauts on the moon first?
The United States won the race for a manned space mission to the moon. |
What seven houses ruled the Seven Kingdoms before Aegon's Conquest?
Stark, Tully, Arryn, Lannister, Tyrell, Baratheon, and Martell |
What is the correlation between interest rates and bond prices?
As interest rates rise, bond prices fall. This is because new bonds are selling at more attractive rates. |
Who directed Terror Mountain, a American silent Western film?
Louis King is a director of the film. |
Will commercial space travel be affordable to me in my lifetime and what would I pay for it?
I have always been fascinated by space and space travel. The cost of space travel is astronomical by most peoples standards, however, we are starting to hear of companies that are working on making space travel more affordable. Depending on my financial situation at retirement, I would pay up to $100000 to travel to space. |
Give me a bulleted list of the the first five books in the bible new testament?
The New Testament is the second division of the Christian biblical canon. It discusses the teachings and person of Jesus, as well as events in first-century Christianity. The first five books of the new testament are
1) The Gospel of Matthew - It is one of the four gospels of the New Testament that tell the story of Jesus' life and teachings.
2 The Gospel of Mark - It tells of the ministry of Jesus from his baptism by John the Baptist to his death, burial, and the discovery of his empty tomb. It portrays Jesus as a teacher, an exorcist, a healer, and a miracle worker, though it does not expound upon the miraculous birth or divine pre-existence.
3) The Gospel of Luke - tells of the origins, birth, ministry, death, resurrection, and ascension of Jesus Christ.
4) The Gospel of John - It contains a highly schematic account of the ministry of Jesus, with seven "signs" culminating in the raising of Lazarus and seven "I am" discourses culminating in Thomas' proclamation of the risen Jesus as "my Lord and my God". The gospel's concluding verses set out its purpose, "that you may believe that Jesus is the Christ, the Son of God, and that believing you may have life in his name
5) Acts of the Apostles - is an attempt to answer a theological problem, namely how the Messiah, promised to the Jews, came to have an overwhelmingly non-Jewish church; the answer it provides, and its central theme, is that the message of Christ was sent to the Gentiles because the Jews rejected it |
Classify these quarterback as either won Superbowl or did not win: Joe Montana, Dan Marino, Jim Kelly, John Elway.
Won Superbowl: Joe Montana, John Elway
Did not win Superbowl: Dan Marino, Jim Kelly |
Why is it important to brush and floss your teeth everyday?
It is important to use a toothbrush to remove food build-up and plaque that can accumulate on tooth surfaces. Flossing is important to remove build-up in between teeth in the areas a toothbrush cannot reach. If plaque is not removed within 24 hours, it can harden into calculus which can only be removed with a professional cleaning. If plaque and calculus remain on teeth it can increase the risk of gum disease and cavities. Maintaining a healthy mouth is important for oral health as well as systemic health, e.g. Cardiovascular Health. Dentists recommend to brush your teeth twice a day for 2 minutes each time and flossing at least once a day. When brushing it is best to wait 30 minutes after drinking acidic beverages, such as coffee or citrus juice. Dentists recommend using a soft bristle toothbrush with gentle pressure and using toothpaste with fluoride which can help reduce the risk of cavities by strengthening the enamel. |
What are some of the best places to eat in Boston?
There are many types of restaurants in Boston. Boston is well known for its local seafood, lobster, scollops, shrimp, and many types of fish. Boston is also a waterfront city, so there are many dinning options available on the water. |
How many types of cat does the world cat federation recognise?
69 |
Who wrote the Man in the Iron Mask
Alexander Dumas |
What is the history of coffee?
Much of the early history of coffee was tied to oral tradition in modern-day Ethiopia. Presently, there is no evidence of coffee consumption and cultivation before the 15th century. Yemeni monks drank coffee to aid in concentration during prayers. In the early 16th century, coffee spread to the Levant and Persia. Later in the 16th-century coffee arrived in Italy via Mediterranean trade routes. The Ottomans brought it to Central and Eastern Europe. It reached India by the mid-17th century.England and Germany pioneered the coffee house concept that emerged in Western Europe. The Caribbean island of Martinique hosted one of the earliest ex-situ coffee cultivations in the New World - Gabriel de Clieu brought coffee seedlings here in 1720. These resulted in coffee plantations in other Caribbean islands like Saint-Domingue (which, by 1788, supplied half of the world's coffee) and also in Mexico.Brazil is currently the largest coffee producer globally, a status held since 1852. Since 1950, a number of other major producers emerged, including Colombia, Ivory Coast, Ethiopia, and Vietnam. Today, coffee is a household item as a result of modern production techniques and mass productization. |
Imagine you are someone's shadow for a day. Write about your experiences in the present tense.
I'm feeling surprised this morning. I feel a little flatter than usual, and a little lighter. To be honest with you, I can't see myself at all.
WOW! Someone turned the lights on. I can't see! Wait... I'm on the floor. Why am I on the floor? I'm right behind this man, he's just got out of bed. I don't recognise this room.
Ah. I seem to be a shadow. Not what I was hoping for this morning, if I'm being honest. I have a big day at work, and this is going to make things rather more challenging. I'll have to get on with it though, stiff upper lip and all that. I can only hope this my shadow's driver has an interesting plan for the day.
It's looking promising so far. They are putting on hiking boots and other outdoor wear. Certainly better than staying inside and playing video games all day. I'd hardly have anything to do at all. Now we need to hope for some good weather. If we're in Norway, there isn't much light at this time of the year. I'd barely even exist.
Finally, he's opened the curtains. I've struck gold. We're in the Sierra Nevada mountains in Spain, and it's a clear day.
We're outside and we're climbing. This is fun! But scary! I never climbed before in my real body. I wish he would stop sitting down to rest. I don't like being sat on.
The view from the summit, it's finally here. It's amazing. Or at least that is what the man says. As a 2 dimensional shadow, I can't really see much. I'm not tall enough. |
In the series A Song of Ice and Fire, who is the founder of House Redwyne?
Gilbert of the Vines |
When did Phil Knight announce he would step down as chairman of Nike
Phil Knight announced he would step down in 2015 as chairman and offically stepped down in 2016 |
Who is the author of Harry Potter?
J.K. Rowling is the British author of the seven-volume Harry Potter series |
What is geomorphometry?
Geomorphometry, or geomorphometrics, is the science and practice of measuring the characteristics of terrain, the shape of the surface of the Earth, and the effects of this surface form on human and natural geography. It gathers various mathematical, statistical and image processing techniques that can be used to quantify morphological, hydrological, ecological and other aspects of a land surface. Common synonyms for geomorphometry are geomorphological analysis (after geomorphology), terrain morphometry, terrain analysis, and land surface analysis. Geomorphometrics is the discipline based on the computational measures of the geometry, topography and shape of the Earth's horizons, and their temporal change. This is a major component of geographic information systems (GIS) and other software tools for spatial analysis.
In simple terms, geomorphometry aims at extracting (land) surface parameters (morphometric, hydrological, climatic etc.) and objects (watersheds, stream networks, landforms etc.) using input digital land surface model (also known as digital elevation model, DEM) and parameterization software.[Extracted surface parameters and objects can then be used, for example, to improve mapping and modelling of soils, vegetation, land use, geomorphological and geological features and similar.
With the rapid increase of sources of DEMs today (and especially due to the Shuttle Radar Topography Mission and LIDAR-based projects), extraction of land surface parameters is becoming more and more attractive to numerous fields ranging from precision agriculture, soil-landscape modelling, climatic and hydrological applications to urban planning, education and space research. The topography of almost all Earth has been today sampled or scanned, so that DEMs are available at resolutions of 100 m or better at global scale. Land surface parameters are today successfully used for both stochastic and process-based modelling, the only remaining issue being the level of detail and vertical accuracy of the DEM. |
What does troll the respawn, Jeremy mean?
Trolling the respawn refers to when in video games a player hangs out at a place where their opponent respawns, or comes back into a game after dying to immediately kill them again. Troll the respawn, Jeremy specifically is a quote from a TV show Unbreakable Kimmy Schmidt and is misunderstood as a greeting one says when hanging up the phone. |
Who won the World Chess Championship in 2021?
Magnus Carlsen defeated Ian Nepomniachtchi 7.5 - 3.5 to become the 2021 World Chess Champion. |
Why is it a good idea to walk every day?
Walking is a good exercise for burning calories without causing any damage to joints. People of any age can do it and a few miles a day can result in positive effects on cardiovascular health and general fitness. |
Who is the creator of Python?
Guido van Rossum is the father of Python. And the 1st version of Python was released in 1991. |