words
sequence | labels
sequence | tag_mask
sequence | panel_id
stringlengths 1
6
⌀ |
---|---|---|---|
[
"E",
":",
"Western",
"blot",
"analysis",
"of",
"PITRM1",
"in",
"primary",
"fibroblasts",
"(",
"left",
")",
"and",
"skeletal",
"muscle",
"(",
"right",
")",
"of",
"controls",
"(",
"CTR",
")",
"and",
"subject",
"II",
"-",
"2",
".",
"Densitometric",
"quantification",
"using",
"the",
"Genetools",
"software",
"is",
"shown",
"below",
"the",
"blots",
".",
"In",
"blue",
"is",
"PITRM1WT",
"and",
"in",
"red",
"PITRM1R183Q",
"."
] | [
0,
0,
13,
14,
0,
0,
3,
0,
0,
7,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0
] | [
0,
0,
1,
1,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0
] | 16864 |
[
"(",
"g",
",",
"h",
")",
"ELISA",
"of",
"IL",
"-",
"1β",
"secretion",
"(",
"left",
")",
"and",
"immunoblot",
"analysis",
"for",
"caspase",
"-",
"1",
"in",
"lysates",
"(",
"right",
")",
"of",
"Map1lc3b",
"+",
"/",
"+",
"and",
"Map1lc3b",
"−",
"/",
"−",
"(",
"g",
")",
"or",
"Becn1",
"+",
"/",
"+",
"and",
"Becn1",
"+",
"/",
"−",
"(",
"h",
")",
"peritoneal",
"macrophages",
"incubated",
"for",
"1",
"h",
"with",
"Mito",
"-",
"TEMPO",
"(",
"500",
"μM",
")",
",",
"followed",
"by",
"LPS",
"and",
"ATP",
".",
"*",
"P",
"0",
".",
"05",
"(",
"Student",
"'",
"s",
"t",
"-",
"test",
")",
".",
"Data",
"represent",
"three",
"experiments",
"(",
"mean",
"and",
"s",
".",
"d",
".",
"in",
"a",
",",
"c",
",",
"d",
"-",
"h",
")",
"."
] | [
0,
0,
0,
0,
0,
13,
0,
3,
4,
4,
0,
0,
0,
0,
0,
13,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 10462 |
[
"A",
".",
"Representative",
"plots",
"of",
"splenocytes",
"from",
"CD45",
".",
"1",
"mice",
"adoptively",
"transferred",
"with",
"CD45",
".",
"2",
"OT",
"-",
"II",
"WT",
"or",
"CCR5",
"-",
"/",
"-",
"lymph",
"node",
"cell",
"suspensions",
",",
"five",
"weeks",
"after",
"infection",
"with",
"rVACV",
"-",
"OVA",
"virus",
".",
"The",
"gating",
"strategy",
"used",
"to",
"identify",
"the",
"memory",
"CD4",
"+",
"T",
"cell",
"subtypes",
"is",
"shown",
"(",
"n",
"=",
"5",
")",
"."
] | [
0,
0,
0,
0,
0,
7,
0,
3,
4,
4,
11,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
3,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 85458 |
[
"C",
".",
"HuH7",
"cells",
"were",
"transfected",
"with",
"a",
"control",
"gapmer",
"or",
"with",
"two",
"gapmers",
"targeting",
"EGOT",
".",
"One",
"day",
"later",
",",
"the",
"cells",
"were",
"infected",
"with",
"a",
"moi",
"0",
".",
"3",
"of",
"HCV",
"for",
"12",
"and",
"24h",
".",
"RNA",
"was",
"isolated",
"and",
"the",
"levels",
"of",
"EGOT",
",",
"ISG15",
"mRNA",
"and",
"the",
"genome",
"equivalents",
"of",
"HCV",
"(",
"GE",
")",
"/",
"μg",
"of",
"total",
"RNA",
"were",
"evaluated",
"by",
"qRT",
"-",
"PCR",
".",
"The",
"experiments",
"were",
"performed",
"at",
"least",
"twice",
"in",
"triplicate",
"(",
"n",
"=",
"6",
")",
".",
"Average",
"values",
"are",
"shown",
".",
"Asterisks",
"mark",
"significant",
"differences",
"(",
"ns",
",",
"non",
"-",
"significant",
",",
"*",
"denotes",
"p",
"<",
"0",
".",
"05",
",",
"*",
"*",
"p",
"<",
"0",
".",
"01",
",",
"*",
"*",
"*",
"p",
"<",
"0",
".",
"001",
")",
"obtained",
"with",
"a",
"two",
"-",
"tailed",
"non",
"-",
"parametric",
"Mann",
"-",
"Whitney",
"U",
"-",
"test",
"."
] | [
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 26329 |
[
"(",
"D",
")",
"Both",
"N",
"-",
"and",
"C",
"-",
"terminal",
"domains",
"of",
"LC3B",
"are",
"needed",
"for",
"efficient",
"interaction",
"with",
"FYCO1",
".",
"GST",
",",
"GST",
"-",
"LC3B",
",",
"or",
"its",
"deletion",
"mutants",
"were",
"incubated",
"with",
"[",
"S35",
"]",
"methionine",
"-",
"labeled",
"myc",
"-",
"FYCO1",
"and",
"processed",
"as",
"in",
"Fig",
".",
"1",
"C",
".",
"ARG",
",",
"autoradiography",
";",
"CB",
",",
"Coomassie",
"blue",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
13,
14,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
0
] | 13607 |
[
"(",
"I",
")",
"Co",
"-",
"immunolabelling",
"of",
"VenusClC",
"-",
"3",
"(",
"green",
")",
"with",
"synaptophysin",
"(",
"red",
")",
"of",
"immobilized",
"SVs",
"imaged",
"with",
"TIRF",
"microscopy",
".",
"Vesicle",
"in",
"quadrant",
"delimited",
"by",
"dashed",
"line",
"is",
"shown",
"in",
"higher",
"magnification",
"in",
"merge",
".",
"Scale",
"bar",
",",
"2",
"µm",
"."
] | [
0,
0,
0,
13,
14,
14,
0,
3,
4,
4,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
5,
13,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
1,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 90951 |
[
"(",
"B",
")",
"Representative",
"images",
"from",
"primary",
"tumour",
"stained",
"for",
"H",
"&",
"E",
",",
"cytokeratin",
"19",
"(",
"CK19",
")",
",",
"α",
"-",
"SMA",
",",
"Sirius",
"Red",
"and",
"polarized",
"Sirius",
"Red",
".",
"Scale",
"bar",
",",
"100",
"μm",
"."
] | [
0,
0,
0,
0,
13,
0,
0,
0,
13,
0,
13,
14,
14,
0,
3,
4,
0,
3,
0,
0,
3,
4,
4,
0,
1,
2,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
1,
1,
0,
1,
1,
0,
1,
0,
0,
1,
1,
1,
0,
1,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0
] | 93669 |
[
"D",
"Quantification",
"of",
"cristae",
"per",
"mitochondrial",
"section",
"from",
"different",
"mitochondria",
"in",
"WT",
",",
"MIC10",
"and",
"MIC60",
"KO",
"HAP1",
"cells",
"using",
"EM",
"represented",
"as",
"boxplots",
".",
"Boxplots",
"show",
"median",
"and",
"interquartile",
"range",
"from",
"25",
"to",
"75",
"percentile",
"and",
"whiskers",
"represent",
"minimum",
"and",
"maximum",
"value",
".",
"Data",
"from",
"n",
"=",
"55",
"-",
"69",
"mitochondria",
"(",
"from",
"2",
"independent",
"experiments",
")",
"are",
"shown",
"as",
"data",
"points",
"in",
"the",
"boxplots",
".",
"*",
"*",
"*",
"*",
"P",
"<",
"0",
".",
"0001",
"(",
"using",
"unpaired",
"Student",
"'",
"s",
"t",
"-",
"test",
")",
"."
] | [
0,
0,
0,
5,
0,
5,
0,
0,
0,
5,
0,
0,
0,
3,
0,
3,
0,
7,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 87883 |
[
"Glycine",
"and",
"proline",
"representation",
"in",
"protein",
"acid",
"hydrolysates",
"of",
"untreated",
"NIH",
"-",
"3T3",
"cells",
"and",
"their",
"secreted",
"ECM",
",",
"produced",
"as",
"in",
"Figure",
"1d",
".",
"Amino",
"acids",
"were",
"measured",
"by",
"GC",
"-",
"MS",
"."
] | [
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
0,
13,
14,
14,
0
] | [
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
1,
1,
1,
0
] | 80459 |
[
"(",
"E",
")",
"The",
"sensitivity",
"and",
"specificity",
"of",
"the",
"LAMP",
"assay",
"from",
"201",
"patients",
"(",
"132",
"negative",
"and",
"69",
"positive",
"for",
"SARS",
"-",
"CoV",
"-",
"2",
",",
"as",
"measured",
"by",
"qRT",
"-",
"PCR",
")",
".",
"Thresholds",
"are",
"DNA",
"quantified",
"by",
"the",
"Quantifluor",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
11,
12,
12,
12,
12,
0,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
1,
0,
0,
0,
13,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0
] | 88675 |
[
"Representative",
"confocal",
"images",
"of",
"co",
"-",
"cultured",
"donor",
"and",
"acceptor",
"CAD",
"cells",
".",
"Cells",
"were",
"co",
"-",
"cultured",
"in",
"control",
"conditions",
"or",
"treated",
"with",
"0",
".",
"2",
"%",
"DMSO",
",",
"200",
"µM",
"H2O2",
",",
"200",
"ng",
"/",
"mL",
"Wnt7a",
",",
"10",
"μM",
"KN",
"-",
"93",
",",
"200",
"ng",
"/",
"mL",
"Wnt7a",
"plus",
"10",
"μM",
"KN",
"-",
"93",
",",
"1",
"μM",
"TAT",
"or",
"200",
"ng",
"/",
"mL",
"Wnt7a",
"plus",
"1",
"μM",
"TAT",
"for",
"4",
"h",
".",
"Yellow",
"arrows",
"point",
"to",
"DiD",
"-",
"labeled",
"vesicles",
"inside",
"acceptor",
"cells",
".",
"Percentage",
"of",
"acceptor",
"cells",
"containing",
"DiD",
"-",
"labeled",
"vesicles",
"in",
"the",
"co",
"-",
"culture",
"systems",
"with",
"the",
"indicated",
"treatments",
"."
] | [
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
3,
0,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
3,
0,
0,
0,
1,
2,
2,
0,
0,
0,
1,
0,
0,
0,
0,
0,
3,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 76366 |
[
"For",
"each",
"cell",
"line",
",",
"genes",
"were",
"ranked",
"according",
"to",
"hypoxic",
"induction",
"(",
"0",
".",
"5",
"%",
"hypoxia",
"for",
"16",
"hours",
")",
"in",
"RNA",
"-",
"seq",
"analyses",
"(",
"n",
"=",
"3",
")",
".",
"Enrichment",
"of",
"genes",
"(",
"TSS",
")",
"closest",
"to",
"each",
"canonical",
"HIF",
"-",
"α",
"/",
"β",
"binding",
"site",
"(",
"i",
".",
"e",
".",
"identified",
"in",
"both",
"HIF",
"-",
"1α",
"(",
"or",
"HIF",
"-",
"2α",
")",
"and",
"both",
"HIF",
"-",
"1β",
"ChIP",
"-",
"seq",
"experiments",
")",
"was",
"then",
"examined",
"using",
"Gene",
"Set",
"Enrichment",
"Analysis",
"(",
"ES",
"=",
"enrichment",
"score",
",",
"NES",
"=",
"normalized",
"enrichment",
"score",
")"
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
3,
4,
4,
0,
0,
0,
3,
4,
4,
13,
14,
14,
0,
0,
0,
0,
0,
0,
13,
14,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
1,
1,
1,
0,
0,
0,
1,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 62839 |
[
"(",
"F",
")",
"Negative",
"-",
"stain",
"electron",
"micrographs",
"of",
"Dyn1WT",
",",
"Dyn1ΔΔ",
"and",
"Dyn1Closed",
"assembled",
"onto",
"lipid",
"nanotubes",
".",
"Scale",
"bar",
"=",
"200",
"nm"
] | [
0,
0,
0,
0,
0,
0,
13,
14,
0,
3,
0,
3,
0,
3,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
1,
1,
0,
1,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 18042 |
[
"F",
",",
"G",
".",
"Flow",
"cytometry",
"analysis",
"of",
"distribution",
"(",
"F",
")",
"and",
"cell",
"numbers",
"(",
"G",
")",
"of",
"IgG1",
"+",
"and",
"IgG1",
"-",
"HEL3x",
"-",
"binding",
"Ahr",
"+",
"/",
"+",
"CD45",
".",
"1",
"+",
"CD45",
".",
"2",
"+",
"(",
"black",
")",
"and",
"Ahr",
"-",
"/",
"-",
"CD45",
".",
"2",
"+",
"(",
"white",
")",
"cells",
"harvested",
"from",
"host",
"mice",
".",
"Representative",
"data",
"of",
"n",
"=",
"2",
"independent",
"experiments",
";",
"two",
"-",
"tailed",
"paired",
"t",
"test",
"."
] | [
0,
0,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
3,
0,
3,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 32476 |
[
"ERK7",
"expressing",
",",
"fat",
"body",
"clone",
"contains",
"less",
"(",
"I",
")",
"and",
"smaller",
"(",
"J",
")",
"lipid",
"droplets",
"than",
"control",
"cells",
"(",
"N",
"=",
"11",
"for",
"control",
"and",
"4",
"for",
"ERK7",
"overexpression",
")",
"."
] | [
3,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0
] | [
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0
] | 95672 |
[
"A",
".",
"Control",
"(",
"Ctrl",
")",
"or",
"STING",
"-",
"KO",
"MC38",
"cells",
"were",
"treated",
"in",
"vitro",
"with",
"STING",
"agonist",
"cGAMP",
"(",
"left",
")",
"for",
"6",
"hours",
"or",
"5",
"-",
"FU",
"(",
"right",
")",
"or",
"relevant",
"vehicle",
"controls",
"for",
"24",
"hours",
".",
"The",
"expression",
"of",
"indicated",
"genes",
"was",
"determined",
"by",
"qRT",
"-",
"PCR",
".",
"N",
"=",
"3",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
7,
0,
0,
0,
0,
0,
0,
3,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0
] | 112512 |
[
"(",
"C",
")",
"The",
"timing",
"of",
"bipolarity",
"establishment",
"in",
"the",
"acentrosomal",
"pole",
",",
"chromosome",
"alignment",
",",
"and",
"anaphase",
"onset",
"Each",
"plot",
"shows",
"the",
"cumulative",
"percentage",
"of",
"each",
"event",
"at",
"individual",
"time",
"points",
"(",
"N",
"=",
"49",
"cells",
"from",
"two",
"independent",
"experiments",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
13,
14,
0,
0,
5,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 78686 |
[
"One",
"-",
"cell",
"stage",
"embryos",
"were",
"injected",
"animally",
"with",
"increasing",
"concentrations",
"of",
"bmp4",
"encoding",
"mRNA",
"(",
"75",
"-",
"200",
"pg",
")",
".",
"AC",
"explants",
"were",
"removed",
"from",
"control",
"and",
"injected",
"embryos",
"at",
"blastula",
"stage",
"9",
",",
"and",
"explants",
"were",
"cultured",
"to",
"gastrula",
"stage",
"11",
"-",
"11",
".",
"5",
".",
"Total",
"RNA",
"was",
"isolated",
"from",
"five",
"control",
"embryos",
"(",
"lane",
"2",
")",
",",
"and",
"from",
"eighteen",
"ACs",
"from",
"each",
"group",
"(",
"lanes",
"3",
"-",
"6",
")",
".",
"Marker",
"expression",
"was",
"determined",
"by",
"sqRT",
"-",
"PCR",
".",
"Xenopus",
"brachyury",
"(",
"xbra",
")",
"expression",
"was",
"induced",
"by",
"BMP4",
"in",
"a",
"dose",
"-",
"dependent",
"manner",
".",
"Marker",
"expression",
"was",
"determined",
"by",
"sqRT",
"-",
"PCR",
".",
"Neither",
"dorsal",
"(",
"chd",
",",
"goosecoid",
"-",
"gsc",
")",
"or",
"ventral",
"-",
"lateral",
"(",
"osr1",
")",
"mesoderm",
"markers",
"were",
"induced",
"by",
"BMP4",
".",
"Sox2",
"/",
"3",
"neural",
"markers",
"are",
"expressed",
"in",
"the",
"ACs",
"and",
"are",
"unchanged",
"by",
"BMP",
"expression",
".",
"EF1α",
"is",
"the",
"control",
"for",
"quantitating",
"RNA",
"levels",
".",
"-",
"RT",
"-",
"PCR",
"was",
"performed",
"on",
"total",
"RNA",
"isolated",
"from",
"control",
"embryos",
"(",
"lane",
"1",
")",
"."
] | [
9,
10,
10,
10,
11,
0,
0,
0,
0,
0,
13,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
11,
0,
9,
10,
10,
0,
0,
0,
0,
0,
0,
9,
10,
10,
10,
10,
10,
10,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
13,
14,
14,
0,
3,
4,
0,
3,
0,
13,
0,
0,
0,
3,
0,
0,
13,
14,
14,
0,
0,
0,
13,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
9,
0,
0,
0,
0,
3,
0,
3,
0,
0,
9,
0,
0,
13,
0,
0,
9,
0,
0,
0,
0,
3,
13,
0,
3,
0,
0,
0,
0,
0,
13,
14,
0,
0,
13,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0
] | [
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
1,
1,
0,
1,
0,
1,
0,
0,
0,
1,
0,
0,
1,
1,
1,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
1,
0,
0,
0,
0,
0,
1,
1,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0
] | 72194 |
[
"(",
"F",
")",
"Representative",
"alkaline",
"phosphatase",
"(",
"AP",
")",
"staining",
"images",
"(",
"left",
")",
"and",
"quantification",
"(",
"right",
")",
"of",
"AP",
"+",
"colonies",
"after",
"clonal",
"replating",
",",
"as",
"described",
"in",
"panel"
] | [
0,
0,
0,
0,
3,
4,
0,
3,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 62524 |
[
"B",
".",
"HeLa",
"cells",
"expressing",
"either",
"lncRNA",
"-",
"MIF",
"shRNA",
"or",
"control",
"shRNA",
"were",
"transfected",
"with",
"miR",
"-",
"586",
"inhibitors",
"or",
"NC",
"inhibitors",
"as",
"indicated",
".",
"Colonies",
"were",
"stained",
"with",
"crystal",
"violet",
"and",
"counted",
"after",
"14",
"days",
"incubation",
"."
] | [
0,
0,
7,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0
] | 26580 |
[
"APOE",
"Western",
"blot",
"analysis",
"of",
"equivalent",
"amounts",
"of",
"supernatant",
"protein",
"from",
"CX3CL1",
"-",
"exposed",
"C57BL",
"/",
"6J",
"and",
"Cx3cr1GFP",
"/",
"GFP",
"peritoneal",
"macrophages",
"at",
"24",
"h",
".",
"Soluble",
"Mer",
"receptor",
"tyrosine",
"kinase",
"that",
"is",
"released",
"constitutively",
"from",
"cultured",
"macrophages",
"served",
"as",
"a",
"loading",
"control",
".",
"The",
"experiment",
"was",
"repeated",
"twice",
"with",
"similar",
"results",
"."
] | [
3,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
11,
12,
12,
0,
3,
0,
3,
7,
8,
0,
0,
0,
0,
0,
3,
4,
4,
4,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
1,
1,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 16144 |
[
"(",
"l",
")",
"[",
"Ca2",
"+",
"]",
"m",
"efflux",
"rate",
"derived",
"from",
"j",
"and",
"k",
"during",
"the",
"initial",
"60",
"s",
"following",
"Ru360",
"addition",
"(",
"NS",
";",
"not",
"significant",
";",
"n",
"=",
"3",
")",
"."
] | [
0,
0,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 10686 |
[
"Representative",
"plots",
"of",
"γ",
"-",
"H2AX",
"intensity",
"vs",
"DAPI",
"signal",
"of",
"CCNF",
"K",
"/",
"O",
"cells",
"transfected",
"with",
"empty",
"GFP",
"and",
"GFP",
"-",
"CCNF",
"untreated",
"(",
"top",
"panels",
")",
"and",
"after",
"treatment",
"with",
"1μM",
"Chk1i",
"(",
"LY2603618",
")",
"for",
"20h",
"(",
"bottom",
"panels",
")",
".",
"Normalised",
"γ",
"-",
"H2AX",
"intensity",
"in",
"CCNF",
"K",
"/",
"O",
"cells",
"transfected",
"with",
"either",
"GFP",
"empty",
"vector",
"or",
"GFP",
"-",
"Cyc",
"F",
"and",
"treated",
"with",
"1μM",
"Chk1i",
"for",
"20",
"hours",
".",
"GFP",
"positive",
"cells",
"were",
"gated",
".",
"Data",
"from",
"3",
"independent",
"experiments",
"were",
"plotted",
"with",
"Mean",
"%",
"±",
"SD",
"."
] | [
0,
0,
0,
0,
0,
3,
13,
0,
1,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
13,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
3,
4,
0,
0,
0,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 74219 |
[
"B",
"SU",
"-",
"DHL",
"-",
"4",
"and",
"SU",
"-",
"DHL",
"-",
"6",
"cells",
"were",
"treated",
"with",
"varying",
"doses",
"of",
"BCL2",
"inhibitor",
".",
"Cell",
"viability",
"was",
"measured",
"after",
"24",
"hours",
"of",
"drug",
"treatment",
"using",
"an",
"assay",
"for",
"ATP",
"concentration",
"as",
"a",
"proxy",
"for",
"live",
"cells",
".",
"Traces",
"were",
"generated",
"from",
"at",
"least",
"5",
"independent",
"biological",
"replicates",
".",
"Points",
"represent",
"mean",
"±",
"SD",
"at",
"each",
"dose",
".",
"P",
"value",
"from",
"comparison",
"of",
"dose",
"response",
"between",
"SU",
"-",
"DHL",
"-",
"4",
"and",
"SU",
"-",
"DHL",
"-",
"6",
"cells",
"calculated",
"using",
"sum",
"-",
"of",
"-",
"squares",
"F",
"test",
"is",
"given",
"in",
"the",
"graph",
"key",
".",
"Significance",
"of",
"individual",
"points",
"calculated",
"using",
"two",
"-",
"tailed",
"Student",
"'",
"s",
"t",
"-",
"tests",
"is",
"marked",
"using",
"asterisks",
"on",
"the",
"graph",
".",
"Data",
"information",
":",
"*",
"P",
"≤",
"0",
".",
"05",
",",
"*",
"*",
"P",
"≤",
"0",
".",
"01",
",",
"*",
"*",
"*",
"P",
"≤",
"0",
".",
"001",
"."
] | [
0,
7,
8,
8,
8,
8,
0,
7,
8,
8,
8,
8,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
0,
7,
8,
8,
8,
8,
0,
7,
8,
8,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
1,
1,
1,
1,
1,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
1,
1,
1,
1,
1,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 63781 |
[
"immunoblots",
"of",
"mGPDH",
",",
"phospho",
"-",
"Thr172",
"AMPK",
"(",
"p",
"-",
"AMPK",
")",
",",
"total",
"AMPK",
"(",
"AMPK",
")",
",",
"phospho",
"-",
"Ser79",
"-",
"ACC",
"(",
"p",
"-",
"ACC",
")",
",",
"total",
"ACC",
"and",
"PGC1α",
"and",
"corresponding",
"quantifications",
"represent",
"mGPDH",
",",
"p",
"-",
"AMPK",
",",
"p",
"-",
"ACC",
"and",
"PGC1α",
"protein",
"levels",
"(",
"D",
"-",
"F",
")",
"in",
"C2C12",
"myocytes",
"transfecte",
"wit",
"plasmid",
"for",
"mGPDH",
"24",
"h",
"after",
"differentiation"
] | [
13,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
3,
13,
14,
0,
0,
0,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 63210 |
[
"E",
"Quantification",
"of",
"FOXP3",
"distribution",
"in",
"murine",
"Tregs",
".",
"The",
"degree",
"of",
"FOXP3",
"-",
"nuclear",
"coIocalization",
"in",
"CD4",
"+",
"/",
"FOXP3",
"+",
"cells",
"isolated",
"from",
"the",
"lymph",
"nodes",
"and",
"spleens",
"of",
"Traf6fl",
"/",
"flCD4Cre",
"+",
"and",
"wild",
"type",
"(",
"Traf6fl",
"/",
"flCD4Cre",
"-",
")",
"mice",
"was",
"determined",
"by",
"Imagestream",
"analysis",
",",
"and",
"the",
"frequencies",
"of",
"cells",
"with",
"either",
"a",
"low",
"or",
"high",
"probability",
"of",
"nuclear",
"FOXP3",
"distribution",
"are",
"shown",
"(",
"red",
":",
"nuclear",
"stain",
",",
"green",
":",
"FOXP3",
",",
"Scale",
"bars",
":",
"10",
"um",
")",
"."
] | [
0,
0,
0,
3,
13,
0,
11,
7,
0,
0,
0,
0,
3,
0,
5,
13,
0,
3,
0,
0,
3,
0,
0,
0,
0,
0,
9,
10,
0,
9,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
11,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
3,
13,
0,
0,
0,
0,
0,
5,
13,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
0,
1,
1,
0,
0,
0,
0,
1,
0,
1,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
1,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0
] | 67634 |
[
"A",
"-",
"Toeprinting",
"showing",
"inhibition",
"of",
"initiation",
"complex",
"formation",
"on",
"a",
"truncated",
"dgcM",
"mRNA",
"(",
"210",
"nt",
"from",
"+",
"1",
")",
"by",
"OmrA",
"and",
"OmrB",
".",
"Inclusion",
"of",
"30S",
"ribosomes",
",",
"tRNAfmet",
",",
"OmrA",
",",
"and",
"OmrB",
"is",
"indicated",
".",
"The",
"unrelated",
"IstR",
"-",
"1",
"sRNA",
"is",
"a",
"negative",
"control",
".",
"The",
"30S",
"/",
"tRNAfmet",
"-",
"dependent",
"reverse",
"transcription",
"block",
"(",
"toeprint",
")",
",",
"is",
"indicated",
"by",
"an",
"arrow",
".",
"Sequencing",
"reactions",
"were",
"loaded",
"next",
"to",
"the",
"primer",
"extension",
"products",
"(",
"UCGA",
")",
".",
"The",
"AUG",
"start",
"codon",
"is",
"indicated",
"by",
"asterisks",
"."
] | [
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
5,
6,
0,
1,
0,
3,
0,
0,
3,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
5,
0,
1,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
1,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 72701 |
[
"(",
"B",
")",
"Analysis",
"from",
"the",
"Mitelman",
"database",
"for",
"the",
"fraction",
"of",
"human",
"solid",
"tumors",
"that",
"have",
"lost",
"(",
"top",
")",
"or",
"gained",
"(",
"bottom",
")",
"individual",
"chromosomes",
",",
"that",
"have",
"modal",
"chromosome",
"number",
">",
"2N",
"or",
"~",
"2N",
"(",
"top",
",",
"p",
"<",
"0",
".",
"0001",
"for",
"chromosome",
"1",
"-",
"22",
",",
"X",
"and",
"p",
"<",
"0",
".",
"05",
"for",
"chromosome",
"Y",
";",
"bottom",
",",
"p",
"<",
"0",
".",
"0001",
"for",
"all",
"chromosomes",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0
] | 52837 |
[
"(",
"h",
",",
"i",
")",
"Effect",
"of",
"nutrients",
"and",
"pHi",
"on",
"binding",
"of",
"ARL8",
"and",
"KIF2",
"to",
"polymerized",
"microtubules",
".",
"HeLa",
"cells",
"treated",
"as",
"in",
"(",
"f",
")",
"and",
"(",
"g",
")",
",",
"followed",
"by",
"isolation",
"of",
"polymerized",
"microtubule",
"fraction",
"and",
"western",
"blotting",
".",
"The",
"asterisk",
"indicates",
"a",
"nonspecific",
"band",
".",
"For",
"all",
"panels",
"values",
"are",
"means",
"±",
"s",
".",
"e",
".",
"m",
".",
"of",
"three",
"independent",
"experiments",
"carried",
"out",
"in",
"triplicate",
".",
"All",
"comparisons",
"are",
"with",
"the",
"control",
"within",
"each",
"treatment",
"condition",
",",
"*",
"P0",
".",
"05",
",",
"*",
"*",
"P0",
".",
"01",
",",
"*",
"*",
"*",
"P0",
".",
"005",
"Student",
"'",
"s",
"t",
"-",
"test",
";",
"n",
".",
"s",
".",
"not",
"significant",
".",
"Uncropped",
"images",
"of",
"blots",
"are",
"shown",
"in",
"Supplementary",
"Fig",
".",
"S7",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
5,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 10408 |
[
"C",
".",
"Pictures",
"demonstrating",
"germline",
"transmission",
";",
"endogenous",
"Oct4",
"-",
"GFP",
"signal",
"was",
"detected",
"in",
"the",
"gonads",
"of",
"F1",
"pups",
".",
"Scale",
"bars",
":",
"200",
"μm",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 33474 |
[
"E",
"-",
"H",
"TEM",
"images",
"showing",
"fibril",
"morphology",
"of",
"BSP12",
"(",
"E",
")",
",",
"BSP123",
"(",
"F",
")",
",",
"BSP3",
"(",
"G",
")",
",",
"BSP45",
"(",
"H",
")",
"."
] | [
0,
0,
0,
13,
14,
0,
5,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 109056 |
[
"(",
"A",
")",
"Immunofluorescence",
"microscopy",
"of",
"Sept2",
"(",
"blue",
")",
",",
"mitochondria",
"(",
"Tom20",
",",
"red",
")",
"and",
"Drp1",
"(",
"green",
")",
"in",
"mock",
"treated",
"and",
"Sept2",
"depleted",
"cells",
".",
"Scale",
"bar",
":",
"10",
"µm",
",",
"insets",
"are",
"enlarged",
"fourfold",
".",
"(",
"B",
")",
"Quantification",
"of",
"mitochondria",
"-",
"associated",
"Drp1",
"in",
"mock",
"treated",
"and",
"Sept2",
"depleted",
"cells",
"(",
"mean",
"of",
"3",
"independent",
"experiments",
",",
"n",
"=",
"44",
"-",
"51",
"cells",
")",
"(",
"C",
")",
"Average",
"distance",
"between",
"mitochondria",
"-",
"associated",
"Drp1",
"oligomers",
"(",
"representative",
"experiment",
"with",
"n",
">",
"25",
"individual",
"mitochondria",
")",
"."
] | [
0,
0,
0,
13,
14,
0,
3,
0,
0,
0,
0,
5,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0
] | [
0,
0,
0,
1,
1,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0
] | 23764 |
[
"Autophagosomes",
"and",
"amphisomes",
"do",
"form",
"in",
"ESCRT",
"-",
"depleted",
"cells",
".",
"HeLa",
"cells",
"stably",
"expressing",
"GFP",
"-",
"LC3",
"were",
"transfected",
"with",
"control",
"(",
"A",
")",
",",
"Tsg101",
"(",
"B",
",",
"D",
",",
"and",
"E",
")",
",",
"or",
"Vps24",
"(",
"C",
")",
"siRNA",
"and",
"processed",
"for",
"immuno",
"-",
"EM",
"analysis",
".",
"Cryosections",
"were",
"incubated",
"with",
"antibodies",
"against",
"GFP",
"(",
"15",
"-",
"nm",
"gold",
")",
"and",
"LBPA",
"(",
"10",
"-",
"nm",
"gold",
")",
".",
"Amphisomes",
"(",
"Am",
")",
",",
"characterized",
"by",
"their",
"content",
"of",
"electron",
"-",
"dense",
"LC3",
"-",
"positive",
"areas",
"and",
"intraluminal",
"vesicles",
",",
"were",
"observed",
"in",
"both",
"control",
"(",
"A",
")",
"and",
"ESCRT",
"-",
"depleted",
"cells",
"(",
"B",
"and",
"C",
")",
".",
"(",
"D",
")",
"In",
"the",
"Tsg101",
"-",
"depleted",
"cells",
"we",
"found",
"large",
"clusters",
"of",
"more",
"typical",
"autophagosomes",
"(",
"Au",
")",
"and",
"(",
"E",
")",
"clusters",
"of",
"double",
"-",
"membrane",
"structures",
",",
"consisting",
"of",
"autophagosomes",
"and",
"tubular",
"structures",
"which",
"might",
"represent",
"phagophores",
",",
"all",
"labeling",
"strongly",
"for",
"GFP",
"-",
"LC3",
".",
"We",
"never",
"observed",
"similar",
"clusters",
"in",
"control",
"cells",
"and",
"very",
"rarely",
"in",
"Vps24",
"-",
"depleted",
"cells",
".",
"Bars",
",",
"200",
"nm",
".",
"(",
"F",
")",
"Quantification",
"of",
"amphisomes",
"in",
"control",
"cells",
"and",
"cells",
"depleted",
"for",
"Tsg101",
"or",
"Vps24",
".",
"Approximately",
"20",
"cells",
"were",
"included",
"per",
"siRNA",
"depletion",
"per",
"experiment",
"(",
"n",
"=",
"3",
")",
".",
"Error",
"bars",
"=",
"SEM",
"."
] | [
5,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
13,
14,
14,
0,
0,
13,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 14959 |
[
"B",
".",
"Primary",
"calvaria",
"cells",
"were",
"isolated",
"from",
"the",
"calvariae",
"of",
"4",
"-",
"day",
"-",
"old",
"mice",
"(",
"Manton",
"et",
"al",
",",
"2007",
")",
",",
"and",
"treated",
"with",
"DMSO",
"or",
"KY",
"-",
"02061",
"in",
"DMSO",
"for",
"4",
"days",
".",
"ALP",
"activity",
"levels",
"were",
"visualized",
"by",
"ALP",
"staining",
"."
] | [
0,
0,
0,
9,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
2,
2,
0,
1,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
3,
0,
0
] | [
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0
] | 21005 |
[
"JNK",
"inhibition",
"reduced",
"ER",
"stress",
"-",
"induced",
"apoptosis",
"of",
"MITOL",
"-",
"KO",
"MEFs",
".",
"MEFs",
"were",
"treated",
"with",
"20",
"µM",
"JNK",
"inhibitor",
"-",
"II",
"(",
"JNK",
"inh",
")",
"2",
"hours",
"prior",
"to",
"Tu",
"treatment",
"for",
"24",
"hours",
",",
"followed",
"by",
"immunoblotting",
"with",
"indicated",
"antibodies",
".",
"Error",
"bars",
"represent",
"SD",
"(",
"n",
"=",
"3",
")",
"."
] | [
3,
0,
0,
5,
0,
0,
0,
13,
0,
3,
0,
0,
7,
0,
7,
0,
0,
0,
0,
0,
1,
2,
2,
2,
2,
2,
2,
2,
2,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
1,
1,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 71660 |
[
"D",
".",
"Blood",
"glucose",
"levels",
"for",
"insulin",
"tolerance",
"test",
"(",
"ITT",
")",
"of",
"control",
"(",
"n",
"=",
"4",
")",
"or",
"RbpjiΔEC",
"(",
"n",
"=",
"3",
")",
"mice",
"kept",
"on",
"HFD",
".",
"Data",
"represent",
"unpaired",
"t",
"-",
"test",
",",
"mean",
"±",
"SEM",
".",
"E",
".",
"Quantification",
"of",
"AUC",
"for",
"ITT",
"in",
"D",
".",
"Data",
"represent",
"mean",
"±",
"SEM",
",",
"unpaired",
"t",
"-",
"test",
"."
] | [
0,
0,
9,
1,
13,
0,
13,
14,
14,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
1,
0,
1,
1,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 81259 |
[
"(",
"B",
")",
"Co",
"‐",
"localization",
"of",
"Vti1b",
"with",
"epsinR",
"was",
"quantified",
"by",
"double",
"‐",
"labelling",
"experiments",
"in",
"MSD",
"and",
"MPS",
"‐",
"IIIA",
"(",
"untreated",
"and",
"MβCD",
"treated",
")",
"and",
"in",
"control",
"WT",
"(",
"untreated",
"and",
"cholesterol",
"treated",
")",
"MEFs",
".",
"The",
"chart",
"displays",
"merge",
"values",
"(",
"means",
"±",
"s",
".",
"e",
".",
"m",
".",
")",
"that",
"represent",
"the",
"percentage",
"of",
"Vti1b",
"co",
"‐",
"localizing",
"with",
"epsinR",
"measured",
"in",
"15",
"different",
"cells",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
11,
12,
12,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0
] | 5056 |
[
"D",
".",
"FSC",
"of",
"the",
"electron",
"density",
"map",
"of",
"the",
"T4SS3",
"-",
"10",
"+",
"D4",
"complex",
".",
"The",
"0",
".",
"5",
"line",
"crosses",
"the",
"FSC",
"at",
"a",
"resolution",
"of",
"28",
"Å",
"."
] | [
0,
0,
13,
0,
0,
13,
14,
14,
0,
0,
3,
4,
4,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
1,
1,
1,
0,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 52456 |
[
"Quantification",
"of",
"apoptotic",
"corpse",
"in",
"wild",
"-",
"type",
"(",
"WT",
")",
",",
"brc",
"-",
"1",
"(",
"tm1145",
")",
"and",
"brd",
"-",
"1",
"(",
"gk297",
")",
"strains",
"fed",
"as",
"in",
"(",
"A",
")",
"an",
"treated",
"with",
"ionizing",
"radiation",
"125",
"Gy",
"(",
"IR",
")",
"(",
"D",
")",
".",
"Bar",
"graphs",
"are",
"mean",
"±",
"SEM",
".",
"Data",
"information",
":",
"Data",
"are",
"presented",
"a",
"mean",
"±",
"SEM",
"N",
"=",
"8",
"-",
"10",
"worms",
"per",
"replicate",
"and",
"condition",
",",
"*",
"P",
"<",
"0",
".",
"05",
",",
"*",
"*",
"*",
"P",
"<",
"0",
".",
"001",
"and",
"*",
"*",
"*",
"*",
"P",
"<",
"0",
".",
"0001",
"vs",
"untreated",
";",
"#",
"#",
"#",
"P",
"<",
"0",
".",
"001",
"and",
"#",
"#",
"#",
"#",
"P",
"<",
"0",
".",
"0001",
"vs",
"con",
".",
"Not",
"significant",
"if",
"nothing",
"is",
"specified",
".",
"2",
"-",
"way",
"ANOVA",
"Tukey",
"\"",
"s",
"multiple",
"comparison"
] | [
0,
0,
13,
11,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 63375 |
[
"(",
"e",
")",
"TREX",
"-",
"BCBL",
"-",
"Vector",
"and",
"TREX",
"-",
"BCBL",
"-",
"vFLIP",
"cells",
"were",
"treated",
"with",
"the",
"K",
"-",
"α2",
"and",
"the",
"K",
"-",
"α4",
"(",
"30",
"μM",
"each",
")",
"peptide",
"for",
"12",
"h",
",",
"followed",
"by",
"immunoblotting",
"(",
"IB",
")",
"with",
"anti",
"-",
"LC3",
"and",
"anti",
"-",
"actin",
"antibody",
"."
] | [
0,
0,
0,
7,
8,
8,
0,
0,
0,
7,
8,
8,
0,
3,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0
] | [
0,
0,
0,
1,
1,
1,
0,
0,
0,
1,
1,
1,
0,
1,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0
] | 9963 |
[
"(",
"a",
")",
"SH",
"-",
"SY5Y",
"cells",
"were",
"depleted",
"of",
"WASH1",
",",
"treated",
"with",
"bafilomycin",
"A1",
"and",
"examined",
"for",
"LC3",
"-",
"II",
",",
"tubulin",
",",
"WASH1",
"and",
"GAPDH",
"levels",
".",
"Blots",
"shown",
"are",
"representative",
"of",
"two",
"independent",
"experiments",
"in",
"triplicate",
".",
"(",
"b",
")",
"Quantification",
"of",
"the",
"representative",
"experiment",
"in",
"triplicate",
"shown",
"in",
"(",
"a",
")",
",",
"of",
"two",
"independent",
"experiments",
".",
"Error",
"bars",
"indicate",
"s",
".",
"e",
".",
"m",
".",
"*",
"*",
"P",
"=",
"0",
".",
"0058",
"by",
"1",
"-",
"tailed",
"Student",
"'",
"s",
"t",
"-",
"test",
"."
] | [
0,
0,
0,
7,
8,
8,
0,
0,
0,
0,
3,
0,
0,
0,
1,
2,
0,
0,
0,
3,
0,
0,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 12530 |
[
"Time",
"-",
"course",
"TFL457",
"effects",
".",
"Cells",
"preincubated",
"with",
"peptides",
"(",
"25",
"μM",
",",
"30",
"min",
")",
"were",
"treated",
"with",
"NMDA",
"(",
"0",
"-",
"6",
"h",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 71922 |
[
"(",
"A",
")",
"Total",
"lysates",
"of",
"different",
"mouse",
"organs",
"underwent",
"immunoblotting",
"analysis",
"using",
"anti",
"-",
"Pdia4",
"and",
"anti",
"-",
"actin",
"antibodies",
".",
"Data",
"information",
":",
"Data",
"from",
"3",
"experiments",
"are",
"presented",
"as",
"the",
"mean",
"±",
"SD",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
13,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 117251 |
[
"(",
"D",
",",
"H",
")",
"Cell",
"lysates",
"from",
"indicated",
"MLL",
"-",
"ENL",
"transduced",
"GMP",
"and",
"from",
"indicated",
"leukemic",
"mice",
"(",
"H",
")",
"were",
"blotted",
"with",
"anti",
"-",
"β",
"-",
"catenin",
"(",
"top",
")",
"and",
"anti",
"-",
"actin",
"(",
"bottom",
")",
"antibodies",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0
] | 43158 |
[
"(",
"A",
")",
"HeLa",
"cells",
"expressing",
"wild",
"-",
"type",
"Parkin",
"or",
"E3",
"-",
"inactivating",
"mutations",
"were",
"treated",
"with",
"CCCP",
"and",
"then",
"immunostained",
"with",
"the",
"indicated",
"antibodies",
".",
"When",
"E3",
"-",
"inactivating",
"mutations",
"were",
"introduced",
"into",
"Parkin",
",",
"the",
"mitochondrial",
"ubiquitylation",
"signal",
"disappeared",
"."
] | [
0,
0,
0,
7,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 14211 |
[
"(",
"A",
")",
"Real",
"-",
"time",
"qPCR",
"analysis",
"of",
"ANXA1",
"mRNA",
"levels",
"in",
"SB",
",",
"10C",
",",
"HCT116",
"and",
"DLD1",
"cells",
"incubated",
"with",
"wild",
"-",
"type",
"F",
".",
"nucleatum",
"12230",
"(",
"Fn",
")",
"or",
"fadA",
"-",
"deletion",
"mutant",
"US1",
"(",
"US1",
")",
"at",
"MOI",
"of",
"50",
":",
"1",
"for",
"the",
"indicated",
"time",
"periods",
".",
"The",
"results",
"were",
"normalized",
"to",
"those",
"obtained",
"with",
"untreated",
"cells",
"and",
"were",
"the",
"mean",
"of",
"3",
"independent",
"experiments",
"each",
"performed",
"in",
"triplicates",
".",
"*",
"p",
"<",
"0",
".",
"05",
",",
"*",
"*",
"p",
"<",
"0",
".",
"01",
"and",
"*",
"*",
"*",
"p",
"<",
"0",
".",
"001",
"(",
"two",
"-",
"way",
"ANOVA",
")",
"."
] | [
0,
0,
0,
13,
14,
14,
14,
0,
0,
3,
13,
14,
0,
7,
0,
7,
0,
7,
0,
7,
0,
0,
0,
0,
0,
0,
11,
12,
12,
12,
0,
11,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
1,
1,
0,
0,
1,
1,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 66598 |
[
"I",
"Transcriptional",
"regulation",
"of",
"the",
"Pltp",
"gene",
"by",
"PRDM16",
"and",
"PPARγ",
".",
"ChIP",
"-",
"seq",
"data",
"for",
"PRDM16",
"and",
"PPARγ",
"were",
"obtained",
"from",
"[",
"31",
",",
"32",
"]",
",",
"respectively",
"."
] | [
0,
0,
0,
0,
0,
3,
0,
0,
3,
0,
3,
0,
13,
14,
14,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
1,
1,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 88942 |
[
"Npc2",
"mRNA",
"expression",
"in",
"the",
"purified",
"IMC",
"and",
"AT2",
"populations",
"as",
"determined",
"by",
"quantitative",
"RT",
"-",
"PCR",
".",
"Mean",
"+",
"SD",
"(",
"n",
"=",
"3",
")",
"of",
"Npc2",
"expression",
"normalised",
"to",
"Gapdh",
"is",
"indicated",
"."
] | [
3,
0,
0,
0,
0,
0,
7,
0,
7,
0,
0,
0,
0,
13,
14,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0
] | [
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0
] | 21642 |
[
"(",
"A",
")",
"NSC",
"-",
"34",
"and",
"SH",
"-",
"SY5Y",
"cells",
"were",
"infected",
"with",
"EV",
"-",
"A71",
"S41",
"at",
"MOI",
"30",
"and",
"0",
".",
"01",
",",
"respectively",
".",
"At",
"48",
"h",
".",
"p",
".",
"i",
".",
",",
"cells",
"were",
"fixed",
"and",
"permeabilized",
"prior",
"to",
"immunostaining",
"."
] | [
0,
0,
0,
7,
8,
8,
0,
7,
8,
8,
0,
0,
0,
0,
11,
12,
12,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0
] | [
0,
0,
0,
1,
1,
1,
0,
1,
1,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0
] | 103282 |
[
"G",
".",
"GSK3βCA",
"or",
"vector",
"and",
"Flag",
"-",
"tagged",
"FoxM1",
"(",
"WT",
")",
",",
"mutants",
"S474A",
"or",
"S478A",
"were",
"co",
"-",
"transfected",
"into",
"293T",
"cells",
".",
"Lysates",
"of",
"the",
"cells",
"were",
"subjected",
"to",
"IP",
"with",
"Flag",
"antibody",
"and",
"followed",
"by",
"IB",
"with",
"FoxM1",
"phospho",
"-",
"S474",
"antibody",
"."
] | [
0,
0,
3,
0,
0,
0,
3,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
3,
0,
0,
0,
0,
13,
0,
3,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0
] | 19798 |
[
"A",
"The",
"transcript",
"levels",
"of",
"SlHAK20",
"in",
"TS",
"-",
"670",
"and",
"three",
"independent",
"SlHAK20Hap1",
"-",
"YFP",
"transgenic",
"lines",
"grown",
"under",
"normal",
"growth",
"conditions",
"."
] | [
0,
0,
13,
14,
0,
3,
0,
11,
12,
12,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
0,
1,
0,
1,
1,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0
] | 90013 |
[
"b",
",",
"Macrophages",
"were",
"infected",
"with",
"IPTG",
"-",
"induced",
"iLLO",
"bacteria",
".",
"Arrowheads",
"indicate",
"actin",
"-",
"iLLO",
"bacteria",
"within",
"LAMP1",
"+",
"vacuoles",
"."
] | [
0,
0,
7,
0,
0,
0,
1,
0,
0,
0,
11,
0,
0,
0,
3,
0,
0,
11,
0,
3,
0,
5,
0
] | [
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
1,
0
] | 9392 |
[
"Cell",
"viability",
"analysis",
"using",
"CellTiter",
"-",
"Glo",
"of",
"BN175",
"CRISPR",
"/",
"Cas9",
"Ripk1",
"and",
"Casp",
"-",
"8",
"knockouts",
"(",
"KO",
")",
"cells",
"treated",
"with",
"the",
"indicated",
"agents",
"for",
"18",
"and",
"48",
"hrs",
"(",
"n",
"=",
"3",
"biological",
"replicates",
")",
".",
"Cell",
"viability",
"values",
"are",
"displayed",
"as",
"a",
"percentage",
"of",
"the",
"relative",
"untreated",
"control",
".",
"SM",
"represents",
"SM",
"-",
"164",
".",
"Error",
"bars",
"represent",
"SD",
"and",
"a",
"one",
"-",
"way",
"Anova",
"was",
"performed",
"to",
"compare",
"the",
"mean",
"value",
"of",
"each",
"treatment",
"to",
"the",
"treated",
"BN175",
"CRISPR",
"/",
"Cas9",
"control",
"(",
"Ctrl",
")",
",",
"*",
"*",
"*",
"*",
"P",
"≤",
"0",
".",
"0001",
"."
] | [
13,
14,
0,
0,
13,
14,
14,
0,
7,
0,
0,
3,
4,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
1,
0,
0,
1,
1,
1,
0,
1,
0,
0,
1,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 84657 |
[
"(",
"C",
")",
"Western",
"blot",
"analysis",
"of",
"CRCK3",
"-",
"FLAG",
"proteins",
"in",
"wild",
"type",
"and",
"mpk4",
"-",
"3",
".",
"Total",
"protein",
"was",
"extracted",
"from",
"two",
"-",
"week",
"-",
"old",
"CRCK3",
"-",
"FLAG",
"transgenic",
"plants",
"in",
"WT",
"and",
"mpk4",
"background",
"grown",
"on",
"½",
"MS",
"medium",
"plates",
".",
"The",
"protein",
"extracts",
"were",
"treated",
"with",
"or",
"without",
"λ",
"-",
"PMPase",
"phosphatase",
".",
"The",
"proteins",
"were",
"separated",
"by",
"Phos",
"-",
"tagTM",
"acrylamide",
"gel",
"electrophoresis",
"and",
"CRCK",
"-",
"FLAG",
"proteins",
"were",
"detected",
"by",
"western",
"blot",
"analysis",
"using",
"an",
"anti",
"-",
"FLAG",
"antibody",
".",
"Similar",
"results",
"were",
"obtained",
"in",
"two",
"independent",
"experiments",
".",
"pCRCK3",
",",
"phosphorylated",
"CRCK3",
"-",
"FLAG",
"protein",
"."
] | [
0,
0,
0,
13,
14,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
13,
14,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0
] | [
0,
0,
0,
1,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0
] | 33415 |
[
"(",
"H",
"Western",
"blot",
"assays",
"levels",
"of",
"FN1",
",",
"ITGB3",
"in",
"HCC",
"cells",
"with",
"treatment",
"as",
"indicated",
"(",
"n",
" ",
"=",
" ",
"3",
"independent",
"experiments",
")",
".",
"Data",
"information",
":",
"Graphs",
"show",
"mean",
" ",
"±",
" ",
"s",
".",
"e",
".",
"m",
".",
",",
"two",
"-",
"tailed",
"unpaired",
"t",
"-",
"test",
".",
"*",
"P",
"<",
"0",
".",
"05",
";",
"*",
"*",
"P",
"<",
"0",
".",
"01",
"."
] | [
0,
0,
13,
14,
0,
0,
0,
3,
0,
3,
0,
15,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 127780 |
[
"B",
"-",
"D",
"SclChIP",
"‐",
"seq",
"tracks",
"in",
"WT",
"and",
"Gata1",
",",
"2KO",
"Flk1",
"+",
"MES",
"show",
"Gata1",
"‐",
"and",
"2",
"‐",
"independent",
"Scl",
"binding",
"to",
"Gata1",
"‐",
"and",
"2",
"‐",
"independent",
"Scl",
"binding",
"to",
"key",
"hemato",
"‐",
"vascular",
"regulators",
"(",
"Lyl1",
",",
"Fli1",
")",
"(",
"C",
")",
"and",
"Gata1",
"‐",
"and",
"/",
"or",
"2",
"‐",
"dependent",
"Scl",
"binding",
"to",
"key",
"HSPC",
"transcription",
"factors",
"(",
"Myb",
",",
"Runx1",
")",
"(",
"D",
")",
"."
] | [
0,
0,
0,
3,
13,
14,
0,
0,
0,
0,
3,
0,
0,
3,
0,
9,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
7,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0
] | 26219 |
[
"E",
"Representative",
"FV",
"-",
"OSR",
"images",
"of",
"24",
"h",
"serum",
"-",
"starved",
"hTERT",
"-",
"RPE1",
"stably",
"expressing",
"GFP",
"-",
"RAB35",
"and",
"stained",
"for",
"GFP",
",",
"EHD1",
"and",
"ARL13B",
".",
"Line",
"profile",
"plots",
"of",
"fluorescence",
"intensity",
"in",
"the",
"proximal",
"cilia",
"region",
"(",
"dashed",
"line",
")",
"are",
"shown",
"to",
"the",
"right",
".",
"Data",
"are",
"mean",
"±",
"S",
".",
"E",
".",
"M",
".",
"(",
"n",
"=",
"6",
"cilia",
")",
",",
"with",
"the",
"solid",
"line",
"in",
"the",
"line",
"profile",
"plots",
"indicating",
"mean",
"and",
"the",
"dotted",
"lines",
"indicating",
"S",
".",
"E",
".",
"M",
".",
"values",
".",
"Scale",
"bars",
";",
"1",
"µm",
"."
] | [
0,
0,
0,
0,
0,
13,
0,
0,
0,
9,
0,
0,
7,
8,
8,
0,
13,
3,
0,
3,
0,
13,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
13,
14,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
1,
1,
1,
0,
1,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 81281 |
[
"(",
"B",
")",
"Levels",
"of",
"aspartate",
"aminotransferase",
",",
"alanine",
"aminotransferase",
",",
"and",
"bilirubin",
"are",
"shown",
"for",
"all",
"patients",
".",
"ALT",
",",
"alanine",
"aminotransferase",
";",
"AST",
",",
"aspartate",
"aminotransferase"
] | [
0,
0,
0,
0,
0,
3,
4,
0,
3,
4,
0,
0,
1,
0,
0,
0,
0,
11,
0,
3,
0,
3,
4,
0,
3,
0,
3,
4
] | [
0,
0,
0,
0,
0,
1,
1,
0,
1,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
1,
1,
0,
1,
0,
1,
1
] | 86663 |
[
"a",
")",
"Histogram",
"of",
"CSPs",
"between",
"free",
"15N",
"-",
"UbcH7",
"and",
"15N",
"-",
"UbcH7",
"-",
"O",
"-",
"Ub",
"identifies",
"UbcH7",
"residues",
"affected",
"by",
"conjugation",
"to",
"Ub",
".",
"Active",
"site",
"(",
"Ser86",
")",
"is",
"indicated",
"with",
"a",
"star",
"and",
"cross",
"-",
"over",
"helix",
"residues",
"(",
"101",
"-",
"113",
")",
"are",
"marked",
"with",
"a",
"gray",
"cylinder",
".",
"INSET",
".",
"CSPs",
"greater",
"than",
"1",
"stdv",
"(",
">",
"0",
".",
"115",
"ppm",
")",
"are",
"highlighted",
"in",
"yellow",
"on",
"a",
"surface",
"representation",
"of",
"UbcH7",
"(",
"PDB",
"1fbv",
")",
".",
"The",
"view",
"on",
"the",
"left",
"shows",
"the",
"surface",
"that",
"contains",
"the",
"UbcH7",
"cross",
"-",
"over",
"helix",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
3,
0,
1,
0,
3,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0
] | 26657 |
[
"(",
"B",
")",
"Confocal",
"images",
"of",
"Ubiquitin",
"colocalization",
"with",
"p62",
"/",
"SQSTM1",
"in",
"HCT116",
"ATG13",
"WT",
"and",
"HCT116",
"ATG13",
"KO",
"cells",
".",
"Cells",
"were",
"grown",
"in",
"full",
"DMEM",
"media",
",",
"fixed",
",",
"labelled",
"with",
"antibodies",
"for",
"Ubiquitin",
"and",
"p62",
"/",
"SQSTM1",
"and",
"imaged",
"(",
"Scale",
"bar",
"=",
"10",
"µm",
")",
"(",
"left",
")",
".",
"Quantification",
"of",
"Ubiquitin",
"colocalization",
"with",
"p62",
"/",
"SQSTM1",
"(",
"right",
")",
".",
"Mean",
"±",
"SEM",
",",
"n",
"=",
"1",
"independent",
"experiment",
"with",
"30",
"technical",
"replicates",
"."
] | [
0,
0,
0,
13,
14,
0,
3,
13,
0,
3,
0,
3,
0,
7,
3,
0,
0,
7,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
13,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
0,
1,
1,
0,
1,
0,
1,
0,
1,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 115366 |
[
"B",
"Quantification",
"of",
"the",
"band",
"intensities",
"following",
"GST",
"-",
"pulldown",
"assays",
"with",
"293T",
"cell",
"lysates",
"expressing",
"the",
"autophagy",
"-",
"related",
"proteins",
"and",
"recombinant",
"GST",
"-",
"CbpFR6",
"shown",
"in",
"Fig",
"EV2D",
"."
] | [
0,
0,
0,
0,
0,
13,
0,
3,
0,
13,
14,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0
] | 83673 |
[
"(",
"d",
")",
"Subcellular",
"fractionation",
"and",
"immunoblotting",
".",
"Jurkat",
"T",
"cells",
"were",
"transduced",
"to",
"express",
"ATG5",
"-",
"ΔNES",
",",
"ATG5",
",",
"or",
"GFP",
".",
"Although",
"increased",
"levels",
"of",
"ATG5",
"were",
"observed",
"in",
"both",
"cytoplasm",
"and",
"nucleus",
",",
"ATG5",
"-",
"ΔNES",
"accumulated",
"following",
"lentiviral",
"gene",
"transfer",
"in",
"the",
"cytoplasm",
"only",
".",
"Full",
"-",
"length",
"immunoblots",
"are",
"provided",
"in",
"Supplementary",
"Fig",
".",
"S11",
"."
] | [
0,
0,
0,
13,
14,
0,
13,
0,
7,
8,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
5,
0,
5,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
1,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 7867 |
[
"(",
"B",
")",
"Effect",
"of",
"beclin",
"1",
"knockdown",
"on",
"EGFP",
"-",
"GABARAP",
"as",
"well",
"as",
"mCherry",
"-",
"LC3",
"puncta",
"formation",
"in",
"spns1",
"-",
"depleted",
"zebrafish",
"embryos",
".",
"Injection",
"of",
"control",
"(",
"water",
")",
",",
"spns1",
"MO",
"or",
"coinjection",
"of",
"spns1",
"MO",
"and",
"beclin",
"1",
"MO",
"into",
"Tg",
"(",
"CMV",
":",
"EGFP",
"-",
"GABARAP",
";",
"mCherry",
"-",
"LC3",
")",
"fish",
"was",
"performed",
"to",
"evaluate",
"whether",
"the",
"beclin",
"1",
"knockdown",
"reduces",
"or",
"eliminates",
"the",
"aggregation",
"of",
"GFP",
"-",
"GABARAP",
"puncta",
"in",
"comparison",
"with",
"those",
"of",
"LC3",
"caused",
"by",
"the",
"Spns1",
"depletion",
"at",
"84",
"hpf",
".",
"Scale",
"bar",
",",
"10",
"µm",
".",
"Quantification",
"of",
"data",
"presented",
"in",
"the",
"top",
"row",
"(",
"green",
";",
"EGFP",
")",
"(",
"n",
" ",
"=",
" ",
"9",
")",
",",
"middle",
"row",
"(",
"red",
";",
"mCherry",
")",
"(",
"n",
" ",
"=",
" ",
"12",
")",
",",
"and",
"bottom",
"row",
"(",
"yellow",
";",
"merge",
"of",
"EGFP",
"and",
"mCherry",
")",
"(",
"n",
" ",
"=",
" ",
"9",
")",
"in",
"panel",
"B",
"is",
"shown",
"in",
"the",
"right",
"graphs",
";",
"the",
"number",
"(",
"n",
")",
"of",
"animals",
"is",
"for",
"each",
"morphant",
"or",
"water",
"-",
"injected",
"control",
".",
"Three",
"independent",
"areas",
"(",
"periderm",
"or",
"basal",
"epidermal",
"cells",
"above",
"the",
"eye",
")",
"were",
"selected",
"from",
"individual",
"animals",
"."
] | [
0,
0,
0,
0,
0,
3,
4,
0,
0,
3,
0,
3,
0,
0,
0,
3,
0,
3,
0,
0,
0,
3,
0,
0,
11,
12,
0,
0,
0,
0,
0,
1,
0,
0,
3,
0,
0,
0,
0,
3,
0,
0,
3,
4,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
1,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 14031 |
[
"(",
"F",
")",
"Schematic",
"of",
"the",
"different",
"signal",
"durations",
"of",
"Gal4",
"binding",
"and",
"GAL10",
"transcription",
".",
"Gal4",
"binding",
"overlaps",
"with",
"the",
"GAL10",
"transcription",
"for",
"14",
".",
"1s",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
3,
13,
0,
3,
13,
0,
3,
13,
0,
0,
0,
3,
13,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
1,
0,
1,
1,
0,
1,
1,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0
] | 71768 |
[
"B",
"HeLa",
"cells",
"stably",
"expressing",
"GFP",
",",
"GFP",
"-",
"FXR1",
"wild",
"type",
"(",
"WT",
")",
"and",
"GFP",
"-",
"FXR1",
"mutated",
"in",
"the",
"sequence",
"recognized",
"by",
"FXR1",
"siRNA",
"-",
"1",
"(",
"GFP",
"-",
"FXR1",
"-",
"MUT",
"-",
"siRNA1",
")",
"were",
"treated",
"with",
"the",
"indicated",
"siRNAs",
",",
"synchronized",
"by",
"double",
"thymidine",
"block",
",",
"released",
"for",
"24",
"hours",
"and",
"then",
"analysed",
"by",
"immunofluorescence",
"microscopy",
".",
"The",
"percentage",
"of",
"cells",
"with",
"cytoplasmic",
"nucleoporin",
"granules",
"was",
"quantified",
",",
"1000",
"cells",
"were",
"analysed",
"for",
"each",
"graph",
"(",
"mean",
"±",
"SD",
",",
"*",
"*",
"P",
"<",
"0",
".",
"01",
";",
"*",
"*",
"*",
"P",
"<",
"0",
".",
"001",
",",
"N",
"=",
"3",
")",
"."
] | [
0,
7,
0,
0,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
5,
6,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
1,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 89299 |
[
"C",
".",
"TIRF",
"microscopy",
"revealed",
"time",
"courses",
"of",
"the",
"CAR",
"-",
"GFP",
"microcluster",
"formation",
"as",
"CAR",
"T",
"cells",
"spread",
"on",
"the",
"CD19",
"and",
"ICAM",
"-",
"1",
"-",
"coated",
"SLBs",
"."
] | [
0,
0,
13,
14,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
3,
7,
8,
0,
0,
0,
3,
0,
3,
4,
4,
0,
0,
0,
0
] | [
0,
0,
1,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0
] | 89234 |
[
"A",
"αSMA",
"mRNA",
"levels",
"in",
"TGFβ",
"-",
"treated",
"HFL1",
"fibroblasts",
"and",
"the",
"effect",
"of",
"the",
"IRE1α",
"inhibitor",
"4μ8C",
".",
"*",
"P",
"=",
"0",
",",
"001",
"."
] | [
0,
3,
0,
0,
0,
3,
0,
0,
7,
0,
0,
0,
0,
0,
0,
3,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
1,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0
] | 24848 |
[
"(",
"C",
")",
"Diagram",
"shows",
"the",
"autophagic",
"flux",
"of",
"293",
"cells",
"with",
"differently",
"modulated",
"BAG1",
"and",
"BAG3",
"levels",
"as",
"described",
"in",
"(",
"A",
")",
"and",
"(",
"B",
")",
".",
"Autophagic",
"flux",
"was",
"determined",
"by",
"the",
"strength",
"of",
"LC3",
"‐",
"II",
"accumulation",
"in",
"a",
"2",
"‐",
"h",
"treatment",
"period",
"with",
"Pep",
".",
"A",
"/",
"E64",
".",
"Therefore",
",",
"normalised",
"LC3",
"‐",
"II",
"levels",
"in",
"the",
"absence",
"of",
"inhibitors",
"were",
"subtracted",
"from",
"corresponding",
"levels",
"obtained",
"in",
"the",
"presence",
"of",
"Pep",
".",
"A",
"/",
"E64",
".",
"Values",
"are",
"expressed",
"as",
"mean",
"±",
"s",
".",
"e",
".",
"m",
".",
"*",
"P0",
".",
"05",
"versus",
"control",
"‐",
"transfected",
"cells",
",",
"n",
"=",
"3",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
0,
1,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 4744 |
[
"F",
".",
"Immunofluorescence",
"analyses",
"in",
"OSCs",
".",
"Yb",
"bodies",
"disappeared",
"upon",
"Yb",
"depletion",
",",
"which",
"led",
"Armi",
",",
"SoYb",
"and",
"Vret",
"to",
"be",
"localized",
"in",
"the",
"cytosol",
".",
"Yb",
"bodies",
"were",
"detected",
"in",
"OSCs",
"upon",
"Armi",
"depletion",
",",
"but",
"SoYb",
"and",
"Vret",
"localized",
"in",
"the",
"cytosol",
".",
"Armi",
"was",
"detected",
"at",
"Yb",
"bodies",
"upon",
"SoYb",
"or",
"Vret",
"depletion",
".",
"Yb",
"bodies",
"are",
"indicated",
"by",
"white",
"arrows",
".",
"Nuclei",
"are",
"shown",
"in",
"blue",
".",
"Scale",
"bar",
":",
"2",
"μm",
"."
] | [
0,
0,
13,
0,
0,
7,
0,
5,
6,
0,
0,
3,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
0,
13,
0,
0,
5,
0,
5,
6,
0,
0,
0,
7,
0,
3,
0,
0,
0,
3,
0,
3,
13,
0,
0,
5,
0,
3,
0,
0,
0,
5,
6,
0,
3,
0,
3,
0,
0,
5,
6,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
1,
0,
1,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
1,
0,
0,
1,
0,
1,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
1,
1,
0,
0,
1,
0,
1,
0,
0,
0,
1,
1,
0,
1,
0,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 69523 |
[
"(",
"E",
")",
"Increases",
"in",
"P0",
"protein",
"over",
"time",
"also",
"were",
"observed",
"by",
"immunofluorescence",
"analysis",
"at",
"different",
"time",
"points",
",",
"with",
"P0",
"protein",
"expression",
"increasing",
"to",
"a",
"greater",
"extent",
"in",
"nerves",
"of",
"mice",
"treated",
"with",
"4",
"-",
"AP",
".",
"Scale",
"bar",
"=",
"200",
"m",
"."
] | [
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0
] | 31478 |
[
"Confocalimages",
"of",
"yellow",
"fluorescent",
"protein",
"complementation",
".",
"PAT1",
"‐",
"Nc",
"was",
"transiently",
"co",
"‐",
"expressed",
"with",
"either",
"SUMM2",
"‐",
"Nn",
"or",
"At4g12010",
"in",
"N",
".",
"benthamiana",
".",
"Confocalmicroscopy",
"on",
"leaf",
"disks",
"was",
"conducted",
"2",
"days",
"post",
"‐",
"infiltration",
".",
"Merged",
"pictures",
"show",
"overlay",
"of",
"brightfield",
",",
"chlorophyll",
"and",
"eYFP",
".",
"The",
"scale",
"bar",
"corresponds",
"to",
"25",
"μm",
"."
] | [
13,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
11,
12,
12,
0,
13,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
1,
1,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 24568 |
[
"Histological",
"analysis",
"of",
"testes",
"from",
"adult",
"wild",
"-",
"type",
",",
"Tex11",
"KI",
"/",
"KO",
",",
"and",
"Tex11",
"−",
"/",
"Y",
"males",
".",
"RS",
",",
"round",
"spermatids",
";",
"ES",
",",
"elongating",
"spermatids",
";",
"Pa",
",",
"pachytene",
"spermatocytes",
".",
"Scale",
"bar",
",",
"50",
"μm",
"."
] | [
13,
14,
0,
9,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
7,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0
] | [
1,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 21506 |
[
"C",
".",
"Mutation",
"of",
"Miro1",
"EF",
"-",
"hands",
"diminishes",
"Miro1",
"ubiquitination",
"with",
"S65",
"-",
"phosphorylated",
"ubiquitin",
".",
"HEK",
"cells",
"were",
"transfected",
"with",
"EYFP",
"-",
"Parkin",
"with",
"either",
"myc",
"-",
"Miro1",
"-",
"WT",
"or",
"myc",
"-",
"Miro1",
"-",
"EF",
"with",
"or",
"without",
"PINK1",
"-",
"V5",
".",
"Cells",
"were",
"treated",
"with",
"either",
"DMSO",
"or",
"A",
"&",
"O",
"(",
"both",
"10",
"µM",
")",
"for",
"5",
"hrs",
"with",
"the",
"exception",
"of",
"the",
"PINK1",
"-",
"V5",
"group",
".",
"Myc",
"-",
"Miro1",
"was",
"immunoprecipitated",
"and",
"probes",
"were",
"immunoblotted",
"for",
"Miro1",
"(",
"red",
")",
",",
"S65",
"-",
"Phosphoubiquitin",
"and",
"PINK1",
"-",
"V5",
"(",
"green",
";",
"the",
"weak",
"bands",
"marked",
"with",
"the",
"asterisk",
"are",
"nonspecific",
")",
"."
] | [
0,
0,
0,
0,
3,
0,
0,
0,
0,
3,
13,
0,
1,
2,
2,
2,
0,
7,
0,
0,
0,
0,
3,
0,
3,
0,
0,
3,
0,
3,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
3,
0,
3,
0,
13,
0,
0,
0,
13,
0,
3,
0,
0,
0,
0,
1,
2,
2,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
1,
1,
1,
1,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
1,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 63169 |
[
"Images",
"of",
"representative",
"individuals",
"(",
"F",
")",
"of",
"4",
"-",
"day",
"-",
"old",
"seedlings",
"grown",
"with",
"or",
"without",
"supplemental",
"UV",
"-",
"B",
".",
"The",
"scale",
"bar",
"for",
"all",
"lines",
"represent",
"5",
"mm",
"except",
"for",
"cop1",
"-",
"5",
"where",
"the",
"scale",
"bars",
"represent",
"1",
"mm",
".",
"Data",
"Information",
",",
"lines",
"used",
":",
"wild",
"-",
"type",
"(",
"Ws",
")",
",",
"uvr8",
"-",
"7",
",",
"cop1",
"-",
"4",
",",
"cop1",
"-",
"5",
"/",
"Pro35S",
":",
"YFP",
"-",
"COP1",
"(",
"WT",
")",
",",
"cop1",
"-",
"5",
"/",
"Pro35S",
":",
"YFP",
"-",
"COP1Lys422Ala",
",",
"cop1",
"-",
"5",
"/",
"Pro35S",
":",
"YFP",
"-",
"COP1Tyr441Ala",
",",
"cop1",
"-",
"5",
"/",
"Pro35S",
":",
"YFP",
"-",
"COP1Trp467Ala",
"and",
"cop1",
"-",
"5",
".",
"#",
"1",
"and",
"#",
"2",
":",
"independent",
"transgenic",
"lines",
"."
] | [
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
4,
4,
0,
3,
4,
4,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
3,
0,
3,
0,
3,
4,
4,
0,
0,
0,
3,
0,
3,
0,
3,
4,
4,
0,
0,
0,
3,
0,
3,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
1,
1,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
1,
0,
1,
0,
1,
1,
1,
0,
0,
0,
1,
0,
1,
0,
1,
1,
1,
0,
0,
0,
1,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 73704 |
[
"Splenocytes",
"from",
"C57BL",
"/",
"6",
"mice",
"(",
"A",
")",
"or",
"human",
"PBMCs",
"(",
"B",
")",
"were",
"incubated",
"(",
"continuous",
"treatment",
")",
"with",
"DMSO",
",",
"ONX",
"0914",
"(",
"300",
"nM",
")",
",",
"PRN1126",
"(",
"300",
"nM",
")",
",",
"ML604440",
"(",
"300",
"nM",
")",
",",
"LU",
"-",
"001i",
"(",
"300",
"nM",
")",
",",
"PRN1126",
"+",
"ML604440",
"(",
"300",
"nM",
"each",
")",
",",
"or",
"PRN1126",
"+",
"LU",
"-",
"001i",
"(",
"300",
"nM",
"each",
")",
"and",
"stimulated",
"with",
"LPS",
"overnight",
".",
"The",
"IL",
"-",
"6",
"concentration",
"in",
"the",
"supernatant",
"was",
"analyzed",
"by",
"ELISA",
".",
"The",
"highest",
"IL",
"-",
"6",
"concentration",
"from",
"each",
"experiment",
"was",
"set",
"to",
"100",
"%",
".",
"(",
"A",
")",
"Data",
"are",
"presented",
"as",
"the",
"mean",
"±",
"SEM",
"of",
"4",
"independent",
"experiments",
"each",
"measured",
"in",
"triplicates",
".",
"(",
"B",
")",
"Data",
"are",
"presented",
"as",
"the",
"mean",
"±",
"SEM",
"of",
"6",
"different",
"healthy",
"donors",
".",
"All",
"data",
"were",
"statistically",
"compared",
"to",
"the",
"DMSO",
"treated",
"group",
"."
] | [
7,
0,
0,
0,
0,
11,
0,
0,
0,
0,
11,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
2,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0
] | [
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0
] | 71875 |
[
"(",
"b",
")",
"PC12",
"cells",
"expressing",
"Q74",
"-",
"GFP",
"were",
"induced",
"for",
"15",
"h",
"and",
"then",
"treated",
"with",
"inhibitors",
"for",
"48",
"h",
"after",
"switch",
"-",
"off",
".",
"Band",
"intensity",
"quantification",
"(",
"three",
"independent",
"experiments",
")",
"is",
"shown",
"."
] | [
0,
0,
0,
7,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 9823 |
[
"In",
"vivo",
"effect",
"24",
"h",
"after",
"hydrodynamic",
"injection",
"of",
"B",
"mice",
"with",
"plasmids",
"expressing",
"anti",
"-",
"miR",
"-",
"511",
"(",
"n",
"=",
"9",
")",
",",
"anti",
"-",
"miR",
"-",
"CTR",
"(",
"n",
"=",
"9",
")",
"or",
"PBS",
"(",
"n",
"=",
"10",
")",
".",
"TNFR1",
"protein",
"levels",
"in",
"the",
"liver",
"were",
"measured",
"by",
"ELISA",
"24",
"h",
"after",
"hydrodynamic",
"injection",
"(",
"left",
"panel",
")",
".",
"Survival",
"of",
"B",
"mice",
"injected",
"with",
"20",
"μg",
"TNF",
",",
"24",
"h",
"after",
"hydrodynamic",
"injection",
"(",
"middle",
"panel",
")",
".",
"Mice",
"pretreated",
"with",
"anti",
"-",
"miR",
"-",
"511",
"(",
"grey",
",",
"n",
"=",
"10",
")",
"were",
"significantly",
"sensitized",
"for",
"TNF",
"-",
"induced",
"SIRS",
"compared",
"to",
"control",
"groups",
"and",
"had",
"the",
"largest",
"drop",
"in",
"body",
"temperature",
"(",
"right",
"panel",
")",
"12",
"h",
"after",
"injection",
"of",
"25",
"μg",
"TNF",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
9,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
11,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0
] | 17407 |
[
"Confocal",
"laser",
"scanning",
"micrographs",
"of",
"the",
"macrophages",
"from",
"Atx",
"∆",
"ΜΕ",
"/",
"∆",
"ΜΕ",
"mice",
"and",
"Atx",
"+",
"/",
"+",
"littermates",
".",
"Cells",
"were",
"incubated",
"with",
"IgG",
"-",
"opsonized",
"latex",
"beads",
"in",
"the",
"absence",
"/",
"presence",
"of",
"LPS",
"(",
"20",
"ng",
"/",
"mL",
",",
"2",
"h",
")",
"and",
"stained",
"with",
"Phalloidin",
"(",
"F",
"-",
"actin",
")",
"and",
"DAPI",
".",
"Internalized",
"beads",
"were",
"examined",
"under",
"a",
"higher",
"(",
"A",
")"
] | [
13,
14,
14,
14,
0,
0,
7,
0,
3,
0,
0,
0,
0,
0,
11,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
1,
0,
3,
4,
4,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
1,
1,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
1,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 91586 |
[
"(",
"B",
")",
"WT",
"c10orf76",
"also",
"localized",
"to",
"the",
"Golgi",
",",
"however",
",",
"the",
"PI4KB",
"binding",
"deficient",
"mutant",
"of",
"c10orf76",
"(",
"FLH409AAA",
")",
"predominantly",
"localized",
"to",
"the",
"cytosol",
"."
] | [
0,
0,
0,
0,
3,
0,
13,
0,
0,
5,
0,
0,
0,
0,
3,
13,
0,
0,
0,
3,
0,
0,
0,
0,
13,
0,
0,
5,
0
] | [
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
1,
0
] | 80310 |
[
"(",
"B",
")",
"Promoter",
"activity",
"of",
"miR",
"-",
"124",
"in",
"Neuro2",
"A",
"cells",
"with",
"DSCR1",
"reduction",
"or",
"overexpression",
".",
"Firefly",
"luciferase",
"reporter",
"under",
"the",
"control",
"of",
"miR",
"-",
"124",
"promoter",
"is",
"measured",
".",
"Values",
"are",
"shown",
"as",
"mean",
"±",
"SEM",
"and",
"tested",
"for",
"statistical",
"significance",
"by",
"one",
"-",
"way",
"ANOVA",
"followed",
"by",
"Bonferroni",
"post",
"hoc",
"test",
".",
"N",
"=",
"3",
"for",
"each",
"condition",
",",
"*",
"P",
"<",
"0",
".",
"05",
",",
"*",
"*",
"P",
"<",
"0",
".",
"01",
"."
] | [
0,
0,
0,
0,
13,
0,
3,
4,
4,
0,
7,
8,
0,
0,
3,
0,
0,
0,
0,
11,
3,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
1,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 72646 |
[
"A",
",",
"B",
")",
"Plots",
"showing",
"hydrogen",
"-",
"deuterium",
"exchanged",
"peptides",
",",
"after",
"10",
"sec",
"of",
"deuterium",
"exchange",
"of",
"Ame1",
"(",
"B",
")",
",",
"each",
"in",
"COMA",
"or",
"COMA",
"-",
"Nkp1",
"-",
"Nkp2",
".",
"For",
"this",
"representation",
",",
"and",
"all",
"following",
"of",
"this",
"type",
",",
"detected",
"peptides",
"are",
"colour",
"-",
"coded",
"according",
"to",
"their",
"measured",
"deuterium",
"-",
"exchange",
"in",
"%",
"of",
"the",
"maximum",
"measured",
"exchange",
"(",
"1",
"-",
"25",
"%",
":",
"dark",
"blue",
";",
"26",
"-",
"50",
"%",
":",
"light",
"blue",
";",
"51",
"-",
"75",
"%",
":",
"yellow",
";",
"76",
"-",
"100",
"%",
":",
"red",
")",
".",
"Peptides",
"are",
"represented",
"as",
"bars",
".",
"Each",
"bar",
"is",
"plotted",
"row",
"-",
"wise",
"corresponding",
"to",
"its",
"position",
"in",
"the",
"amino",
"-",
"acid",
"sequence",
"of",
"the",
"protein",
"it",
"derives",
"from",
".",
"Amino",
"-",
"acid",
"sequence",
"scheme",
"is",
"illustrated",
"at",
"the",
"top",
"with",
"thin",
"or",
"thick",
"lines",
";",
"thin",
"line",
":",
"flexible",
"element",
":",
"thick",
"line",
":",
"structured",
"segment",
".",
"Positions",
"of",
"predicted",
"coiled",
"coils",
"are",
"shown",
"as",
"helices",
".",
"Plots",
"for",
"full",
"time",
"courses",
"are",
"in",
"Appendix",
"Fig",
"S3C",
",",
"E",
"."
] | [
0,
0,
0,
0,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 52364 |
[
"K",
"-",
"M",
"Confocal",
"images",
"showing",
"expression",
"of",
"hbl",
"‐",
"1",
":",
":",
"gfp",
":",
":",
"hbl",
"‐",
"1",
"reporter",
"in",
"VNC",
"in",
"wild",
"type",
"(",
"K",
")",
",",
"atg",
"‐",
"2",
"(",
"L",
")",
"and",
"epg",
"‐",
"6",
"(",
"M",
")",
"L3",
"larvae",
"."
] | [
0,
0,
0,
13,
0,
0,
0,
0,
3,
4,
4,
0,
0,
3,
0,
0,
3,
4,
4,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
11,
0
] | [
0,
0,
0,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
1,
0,
0,
1,
1,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0
] | 4241 |
[
"E",
".",
"qRT",
"-",
"PCR",
"analysis",
"showing",
"average",
"TBP",
"-",
"normalized",
"fold",
"expression",
"of",
"GATA6",
",",
"ABCG2",
",",
"AMIGO2",
"or",
"SERPINE1",
"in",
"MM099MITF",
"-",
"SOX10",
"-",
"PAX3",
"treated",
"or",
"not",
"with",
"Doxycycline",
"(",
"1μg",
"/",
"ml",
")",
"for",
"24h",
".",
"Data",
"information",
":",
"data",
"are",
"presented",
"as",
"mean",
"values",
"+",
"SD",
"for",
"three",
"biological",
"triplicates",
".",
"The",
"p",
"-",
"value",
"(",
"Student",
"'",
"s",
"t",
"-",
"test",
")",
"is",
"indicated",
",",
"*",
"<",
"0",
".",
"05",
",",
"*",
"*",
"<",
"0",
".",
"01",
";",
"*",
"*",
"*",
"<",
"0",
".",
"001",
"."
] | [
0,
0,
13,
14,
14,
0,
0,
0,
3,
0,
0,
0,
0,
0,
3,
0,
3,
0,
3,
0,
3,
0,
7,
0,
3,
0,
3,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 114244 |
[
"D",
"Trimeric",
"Hsf1",
"were",
"bound",
"to",
"HSE",
"-",
"DNA",
"and",
"the",
"indicated",
"components",
"added",
"at",
"timepoint",
"0",
"."
] | [
0,
0,
3,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 104639 |
[
"H",
".",
"U2OS",
"/",
"GFP",
"-",
"FAM111A",
"cell",
"lines",
"treated",
"or",
"not",
"with",
"DOX",
"were",
"pre",
"-",
"extracted",
",",
"fixed",
"and",
"stained",
"with",
"RPB1",
"antibody",
",",
"and",
"analyzed",
"by",
"QIBC",
"(",
"n",
">",
"2000",
"cells",
"per",
"condition",
")",
".",
"I",
".",
"Quantification",
"of",
"data",
"in",
"(",
"H",
")",
"(",
"red",
"bars",
",",
"mean",
")",
"."
] | [
0,
0,
7,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
13,
0,
3,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 97115 |
[
"B",
".",
"Ectoderm",
"differentiation",
"of",
"the",
"3KI",
"mESC",
"line",
"(",
"marked",
"by",
"the",
"expression",
"of",
"Sox1",
":",
":",
"GFP",
")",
".",
"C",
".",
"Mesendoderm",
"differentiation",
"of",
"the",
"3KI",
"mESC",
"line",
"(",
"marked",
"by",
"the",
"expression",
"of",
"T",
":",
":",
"3xTagBFP",
")",
"."
] | [
0,
0,
9,
13,
0,
0,
0,
7,
0,
0,
0,
0,
0,
13,
0,
3,
0,
0,
3,
0,
0,
0,
0,
9,
13,
0,
0,
0,
7,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
] | 78627 |
[
"A",
".",
"Immunohistochemical",
"staining",
"of",
"tissue",
"arrays",
"containing",
"142",
"breast",
"carcinoma",
"samples",
"(",
"grade",
"I",
":",
"n",
"=",
"29",
",",
"grade",
"II",
":",
"n",
"=",
"69",
",",
"grade",
"III",
":",
"n",
"=",
"44",
")",
"and",
"20",
"normal",
"mammary",
"tissues",
"for",
"TRIM46",
"and",
"HDAC1",
"expression",
".",
"Representative",
"images",
"are",
"shown",
"on",
"the",
"left",
"panel",
".",
"The",
"positively",
"stained",
"cells",
"were",
"analyzed",
",",
"and",
"the",
"mean",
"intensity",
"was",
"scored",
"by",
"Image",
"-",
"Pro",
"Plus",
"software",
"on",
"the",
"right",
"panel",
".",
"In",
"the",
"boxplot",
",",
"the",
"central",
"lines",
",",
"the",
"box",
"limits",
",",
"and",
"the",
"whiskers",
"represented",
"medians",
",",
"25th",
"/",
"75th",
"percentile",
",",
"and",
"min",
"/",
"max",
",",
"respectively",
".",
"(",
"*",
"P",
"<",
"0",
".",
"05",
",",
"*",
"*",
"P",
"<",
"0",
".",
"01",
",",
"*",
"*",
"*",
"*",
"P",
"<",
"0",
".",
"0001",
",",
"one",
"-",
"way",
"ANOVA",
")",
"."
] | [
0,
0,
13,
14,
0,
0,
0,
0,
0,
15,
16,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
3,
0,
3,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
1,
1,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 115997 |
[
"(",
"H",
")",
"Oocytes",
"expressing",
"CDK5RAP2",
"-",
"EGFP",
",",
"histone",
"H2B",
"-",
"mCherry",
"and",
"stained",
"with",
"SiR",
"-",
"tubulin",
"were",
"treated",
"with",
"15",
"µM",
"IPZ",
"after",
"being",
"cultured",
"for",
"5h",
"in",
"control",
"media",
".",
"Maximum",
"intensity",
"z",
"-",
"projections",
"from",
"confocal",
"live",
"-",
"cell",
"imaging",
"are",
"shown",
".",
"Time",
"in",
"hh",
":",
"mm",
"is",
"relative",
"to",
"GVBD",
",",
"DMSO",
"or",
"15",
"uM",
"IPZ",
"was",
"added",
"at",
"time",
"5",
":",
"00",
".",
"Scale",
"bars",
",",
"10",
"µm",
"."
] | [
0,
0,
0,
7,
0,
3,
0,
3,
0,
3,
4,
0,
3,
0,
13,
0,
3,
0,
3,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
13,
14,
14,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
1,
0,
1,
0,
1,
1,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 77222 |
[
"(",
"d",
")",
"GFP",
"-",
"tagged",
"empty",
"vector",
"or",
"GFP",
"-",
"BRLF1",
"-",
"or",
"GFP",
"-",
"BRLF1",
"L578A",
"-",
"expressing",
"plasmids",
"were",
"transfected",
"into",
"A549",
"cells",
",",
"after",
"which",
"the",
"cells",
"were",
"then",
"infected",
"with",
"HSV",
"-",
"1",
",",
"or",
"transfected",
"into",
"HNE",
"-",
"1",
"-",
"EBV",
"-",
"ΔBRLF1",
"cells",
".",
"The",
"cells",
"were",
"then",
"collected",
"and",
"lysed",
".",
"Immunoprecipitation",
"with",
"GST",
"-",
"affinity",
"beads",
"was",
"subsequently",
"performed",
",",
"and",
"then",
"whole",
"-",
"cell",
"lysates",
"and",
"immunoprecipitated",
"complexes",
"were",
"analyzed",
"as",
"indicated",
"."
] | [
0,
0,
0,
3,
0,
0,
0,
0,
0,
3,
0,
3,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
12,
12,
0,
0,
0,
0,
7,
8,
8,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
1,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0
] | 94509 |
[
"(",
"g",
"-",
"i",
")",
"Immunofluorescence",
"of",
"BrdU",
"retention",
"cells",
"in",
"the",
"DG",
"and",
"OB",
"of",
"P31",
"mice",
".",
"Boxed",
"areas",
"in",
"left",
"column",
"of",
"g",
"are",
"shown",
"in",
"more",
"detail",
"in",
"right",
"column",
".",
"Dotted",
"lines",
"indicate",
"the",
"boundaries",
"of",
"the",
"DG",
"(",
"left",
")",
"and",
"GZ",
"(",
"right",
")",
".",
"Arrows",
"mark",
"NeuN",
"+",
"BrdU",
"+",
"cells",
"and",
"arrowheads",
"mark",
"NeuN",
"−",
"BrdU",
"+",
"cells",
"in",
"the",
"DG",
".",
"Mean",
"±",
"s",
".",
"e",
".",
"m",
".",
"of",
"the",
"percentage",
"of",
"NeuN",
"+",
"BrdU",
"+",
"cells",
"of",
"total",
"BrdU",
"retained",
"cells",
"in",
"the",
"DG",
"(",
"h",
")",
"and",
"OB",
"(",
"i",
")",
"are",
"shown",
".",
"(",
"j",
",",
"k",
")",
"Mean",
"±",
"s",
".",
"e",
".",
"m",
".",
"of",
"percentage",
"of",
"GFAP",
"+",
"nestin",
"−",
"BrdU",
"+",
"cells",
"among",
"total",
"BrdU",
"+",
"retained",
"cells",
"in",
"the",
"SVZ",
"(",
"j",
")",
"and",
"SGZ",
"(",
"k",
")",
"."
] | [
0,
0,
0,
0,
0,
13,
0,
13,
0,
0,
0,
0,
9,
0,
9,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
3,
0,
13,
0,
0,
0,
0,
0,
3,
0,
13,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
13,
0,
0,
0,
0,
13,
0,
0,
0,
0,
9,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
3,
0,
13,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
9,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0
] | 8945 |
[
"Immunostaining",
"of",
"PAR",
"-",
"2",
"-",
"5A",
"synthesized",
"in",
"vitro",
".",
"Reaction",
"mixtures",
"were",
"resolved",
"by",
"electrophoresis",
"in",
"a",
"polyacrylamide",
"-",
"8",
"M",
"urea",
"denaturing",
"gel",
",",
"transferred",
"to",
"a",
"charged",
"nylon",
"membrane",
",",
"and",
"probed",
"with",
"mouse",
"anti",
"-",
"PAR",
"10H",
"(",
"left",
"panel",
")",
"or",
"rabbit",
"anti",
"-",
"2",
"-",
"5A",
"after",
"stripping",
"(",
"right",
"panel",
")",
".",
"XC",
":",
"Xylene",
"Cyanol",
"(",
"apparent",
"size",
"150",
"nucleotides",
")",
",",
"BPB",
":",
"Bromophenol",
"Blue",
"(",
"apparent",
"size",
"35",
"nucleotides",
")",
".",
"Lane",
"1",
",",
"purified",
"PARP1",
"alone",
";",
"lane",
"2",
",",
"PAR",
"reaction",
":",
"PARP1",
",",
"activated",
"DNA",
",",
"NAD",
"+",
",",
"and",
"histone",
";",
"lane",
"3",
",",
"2",
"-",
"5A",
"reaction",
":",
"OAS1",
",",
"pIC",
",",
"ATP",
";",
"lane",
"4",
",",
"2",
"-",
"5A",
"and",
"PAR",
"reactions",
":",
"OAS1",
",",
"pIC",
",",
"ATP",
"and",
"PARP1",
",",
"activated",
"DNA",
",",
"NAD",
",",
"histone",
".",
"After",
"incubation",
"at",
"37oC",
"for",
"60",
"min",
",",
"the",
"proteins",
"were",
"removed",
"by",
"digestion",
"with",
"proteinase",
"K",
"."
] | [
13,
0,
1,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
1,
0,
0,
3,
0,
0,
0,
0,
1,
2,
0,
0,
1,
0,
0,
0,
0,
1,
2,
2,
0,
0,
3,
0,
1,
0,
1,
0,
0,
0,
0,
1,
2,
2,
0,
1,
0,
0,
3,
0,
1,
0,
1,
0,
3,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
0
] | [
1,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
0,
0,
1,
0,
0,
0,
0,
1,
1,
1,
0,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
1,
1,
1,
0,
1,
0,
0,
1,
0,
1,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0
] | 90383 |
[
"(",
"b",
")",
"in",
"N2",
"wild",
"type",
"(",
"black",
"diamonds",
")",
"and",
"ung",
"-",
"1",
"mutants",
"(",
"red",
"squares",
")",
",",
"(",
"c",
")",
"following",
"the",
"depletion",
"of",
"EXO",
"-",
"3",
"(",
"red",
"triangles",
")",
",",
"APN",
"-",
"1",
"(",
"blue",
"circles",
")",
"or",
"control",
"RNAi",
"(",
"L4440",
",",
"black",
"diamonds",
")",
"in",
"the",
"N2",
"wild",
"-",
"type",
"background",
",",
"and",
"(",
"d",
")",
"in",
"msh",
"-",
"2",
"(",
"ok2410",
")",
"(",
"orange",
"triangles",
")",
",",
"msh",
"-",
"6",
"(",
"pk2504",
")",
"(",
"green",
"circles",
")",
"and",
"mlh",
"-",
"1",
"(",
"ok1917",
")",
"(",
"grey",
"squares",
")",
"mutants",
"."
] | [
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 12084 |
[
"Tap",
"-",
"1",
"is",
"required",
"for",
"the",
"secretion",
"of",
"TseL",
".",
"Pellet",
"(",
"P",
")",
"and",
"supernatant",
"(",
"S",
")",
"of",
"bacterial",
"cultures",
"were",
"analyzed",
"by",
"SDS",
"-",
"PAGE",
".",
"The",
"result",
"of",
"immunoblotting",
"with",
"antisera",
"against",
"TseL",
"and",
"Hcp",
"and",
"purified",
"antibodies",
"against",
"DnaK",
"is",
"shown",
".",
"The",
"asterisk",
"marks",
"an",
"unspecific",
"band",
",",
"detected",
"by",
"the",
"antiserum",
"against",
"TseL",
",",
"present",
"in",
"the",
"pre",
"-",
"immunized",
"serum",
".",
"One",
"representative",
"experiment",
"of",
"three",
"independent",
"experiments",
"is",
"shown",
"."
] | [
3,
4,
4,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
14,
14,
0,
0,
0,
0,
13,
0,
0,
0,
3,
0,
3,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
1,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 24137 |
[
"(",
"e",
")",
"A",
"GFP",
"-",
"tagged",
"FoxO1",
"(",
"3A",
")",
"or",
"an",
"empty",
"plasmid",
"was",
"co",
"-",
"transfected",
"with",
"a",
"FoxO1",
"-",
"promoter",
"luciferase",
"plasmid",
"into",
"H1299",
"cells",
".",
"After",
"24",
"h",
",",
"luciferase",
"reporter",
"activity",
"of",
"FoxO1",
"was",
"measured",
".",
"RLU",
",",
"relative",
"luciferase",
"units",
".",
"Data",
"are",
"means",
"±",
"s",
".",
"d",
".",
"(",
"n",
"=",
"3",
")",
"."
] | [
0,
0,
0,
0,
3,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
3,
0,
0,
7,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 8703 |
[
"Cellular",
"metabolites",
"were",
"measured",
"by",
"LC",
"-",
"MS",
"-",
"based",
"untargeted",
"metabolomics",
"from",
"extracts",
"of",
"Stage",
"11",
"embryos",
";",
"biological",
"replicates",
"for",
"control",
"n",
"=",
"5",
",",
"for",
"atosPBG",
"n",
"=",
"7",
".",
"Heatmap",
"of",
"non",
"-",
"targeted",
"metabolites",
"in",
"atosPBG",
"compared",
"to",
"wild",
"-",
"type",
"embryos",
"shown",
"with",
"average",
"log2fold",
"change",
"(",
"FC",
")",
"in",
"the",
"non",
"-",
"targeted",
"LC",
"-",
"MS",
"/",
"MS",
"analysis",
"reveals",
"(",
"C",
")",
"an",
"increase",
"in",
"atosPBG",
"in",
"substrates",
"of",
"the",
"dGR",
"/",
"HPR",
"enzyme",
",",
"including",
"4",
"-",
"hydroxy",
"α",
"-",
"ketoglutarate",
"and",
"hydroxyproline",
"(",
"HLP",
")",
"and",
"a",
"smaller",
"decrease",
"in",
"its",
"products",
",",
"glycolate",
"and",
"glycerate",
",",
"(",
"D",
")",
"a",
"significant",
"increase",
"in",
"some",
"dipeptides",
"including",
"those",
"containing",
"hydroxyproline",
".",
"Data",
"information",
":",
"Values",
"in",
"heat",
"maps",
"are",
"obtained",
"from",
"untargeted",
"metabolomic",
"analysis",
",",
"unpaired",
"t",
"-",
"test"
] | [
0,
0,
0,
0,
0,
13,
0,
13,
0,
0,
0,
13,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
13,
14,
14,
0,
0,
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
0,
0,
3,
4,
0,
0,
0,
1,
2,
2,
2,
2,
2,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
13,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
1,
1,
1,
1,
1,
1,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0
] | 125864 |
[
"Representative",
"pictures",
"of",
"lineage",
"tracing",
"in",
"Lgr5",
"-",
"expressing",
"or",
"Lgr5",
"cKO",
"intestine",
"after",
"10",
"days",
"of",
"chase",
"and",
"quantification",
"of",
"the",
"number",
"of",
"traced",
"clones",
"per",
"recombined",
"surface",
"at",
"PN18",
"(",
"ileum",
")",
".",
"Each",
"symbol",
"indicates",
"the",
"value",
"for",
"a",
"given",
"mouse",
"."
] | [
0,
0,
0,
0,
0,
0,
3,
0,
0,
0,
3,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0
] | [
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0
] | 84611 |
[
"D",
"Percentages",
"of",
"axons",
"that",
"initiated",
"regeneration",
"24",
"h",
"after",
"laser",
"surgery",
".",
"The",
"numbers",
"(",
"n",
")",
"of",
"animals",
"examined",
"are",
"shown",
".",
"Error",
"bars",
"indicate",
"95",
"%",
"confidence",
"intervals",
"(",
"CI",
")",
".",
"Data",
"information",
"statistical",
"significance",
"was",
"determined",
"by",
"Fisher",
"'",
"s",
"exact",
"test",
";",
"*",
"P",
"<",
"0",
".",
"05",
";",
"*",
"*",
"*",
"P",
"<",
"0",
".",
"001",
";",
"NS",
";",
"not",
"significant",
"."
] | [
0,
0,
0,
5,
0,
0,
13,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 73837 |
[
"Zoom",
"in",
"to",
"high",
"MW",
"peak",
"shoulder",
"of",
"holo",
"-",
"COP9",
"Signalosome",
"(",
"compare",
"Figure",
"5",
")",
",",
"where",
"defined",
"co",
"-",
"elution",
"signals",
"of",
"CSN",
"substrate",
"components",
"CUL4A",
"and",
"DDB2",
"suggest",
"the",
"partial",
"resolution",
"of",
"substrate",
"-",
"bound",
"and",
"free",
"pools",
"of",
"CSN",
"holo",
"-",
"complex",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
0,
0,
0,
0
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0
] | 65078 |
[
"(",
"F",
")",
"HeLa",
"cells",
"infected",
"with",
"control",
"or",
"PAQR3",
"-",
"overexpressed",
"lentivirus",
"were",
"treated",
"with",
"GS",
"for",
"4",
"h",
".",
"PI",
"(",
"3",
")",
"P",
"levels",
"were",
"determined",
"as",
"in",
"Figure",
"2E",
"(",
"n",
"=",
"5",
";",
"*",
"*",
"p",
"<",
"0",
".",
"01",
";",
"ns",
",",
"not",
"significant",
")",
"."
] | [
0,
0,
0,
7,
0,
0,
0,
0,
0,
3,
0,
0,
11,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | [
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] | 18703 |
[
"IHC",
"images",
"for",
"YAP",
"staining",
"in",
"KPC",
"mice",
"pancreatic",
"tissues",
"(",
"control",
"and",
"treated",
"with",
"2",
"and",
"5",
"mg",
"tamoxifen",
")",
",",
"YAP",
"staining",
"is",
"brown",
".",
"Scale",
"bar",
":",
"100",
"μm"
] | [
13,
14,
0,
3,
13,
0,
0,
11,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
3,
13,
0,
0,
0,
0,
0,
0,
0,
0
] | [
1,
1,
0,
1,
1,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0
] | 62387 |