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### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''biliary cancers remain a tough disease to manage. less is more! standard of care does not change with imbrave151 yet! #gi23 #biliarycancer #cholangiocarcinoma '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''gi23 presented imbrave151 a randomized ph2 trial of gem-cis-atezo +/- bev no major in mpfs. mos data not yet mature but the mos of gem-cis-atezo was actually worse than current options dr. el-khoueiry acknowledged that gem-cis-durva is still the soc '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''superb summary of the current state of frontline btc management by of , including just-presented data from swog 1815 and imbrave151 #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term swog 1815 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''superb summary of the current state of frontline btc management by of , including just-presented data from swog 1815 and imbrave151 #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term swog 1815 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''imbrave151 . 2 experimental arm compared . phase 2 . no clear signal to move it further. as both arm are experimental, there is no p value . #ascogi23 #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''imbrave151 bev doesn't add benefit . we need to better understand how we can prime the immune system to recognize cholangiocarcinoma. #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''imbrave151: concurrent pdl-1 /vgef blockade + chemo as 1l for advanced btc #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' phii imbrave 151 #1l adv cholangio/gb cancer showing cis/gem/bev/atezo modest improvement in primary endpoint pfs (no formal hypothesis testing) w/orr 24.1 vs 25.3% and median os nr vs 11.4 mos compared to cis/gem as key secondary endpoints #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''imbrave151 atezo/bev/chem vs atezo/chemo pfs 1ary objective very modest os immature so let s wait #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term imbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''imbrave151 phase 2 study advanced #biliarycancer improved pfs with bev hr 0.76, same orr ~24%, possible os benefit $gene
#gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term imbrave151 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term IMbrave151 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''subset benefit of atezo/bev/chemo in abtc from imbrave151 #ascogi23 #gi23 '''### Response: The sentiment polarity expressed regarding the given aspect term IMbrave151 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel in hrr negative population.ascogu23 parpi in patients with hrr-negative mcrpc: why would these therapies work in the absence of a mutation? dna proficient tumor cells tx w iparp with hormonal agents, radioligands & io (figures) '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''much awaited data from the ph3 propel shows continued rpfs benefits and strong trend for os (7 month) benefit with abiraterone and olaparib vs. abiraterone in 1st line mcrpc in hrr pos & neg #prostatecancer #mediqgu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term abiraterone in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''much awaited data from the ph3 propel shows continued rpfs benefits and strong trend for os (7 month) benefit with abiraterone and olaparib vs. abiraterone in 1st line mcrpc in hrr pos & neg #prostatecancer #mediqgu23 '''### Response: The sentiment polarity expressed regarding the given aspect term abiraterone in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''much awaited data from the ph3 propel shows continued rpfs benefits and strong trend for os (7 month) benefit with abiraterone and olaparib vs. abiraterone in 1st line mcrpc in hrr pos & neg #prostatecancer #mediqgu23 '''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term talapro-2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''talapro-2 rpfs in unselected crpc with more benefit in hrr'''### Response: The sentiment polarity expressed regarding the given aspect term talapro-2 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''my goodness! a new doublet option in mcrpc #prostatecancer - parpi plus nht, by noel clarke #gu23 .propel study has better overall survival benefit of 7mo very high in this setting. new standard of care? #pcsm '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#gu23 #ascogu all 3 propel combo trials in l1 mcrpc are pointing to need for precision to max therapeutic index . so we agree to treat hrr+. now how to select winners from the hrr- group ? '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#gu23 #propel much awaited final results: 7.4mo improvement in os under abi/ola vs abo/pbo in 1l #mcrpc and a mos>42mo! '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel has excellent summary current state of parpi combination with asis.heterogeneity pointing to need for further refinement of target population. ratio risk / benefit critical #ascogu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term talapro-2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''talapro-2 showed good results in rpfs; os still immature. propel os sub-analysis in non hrd group was underwhelming. great discussion by elena castro. exciting prostate day at #gu23 biomarkers or not biomarkers? hot topic in mcrpc. what do we think? '''### Response: The sentiment polarity expressed regarding the given aspect term talapro-2 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term talapro-2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''talapro-2 showed good results in rpfs; os still immature. propel os sub-analysis in non hrd group was underwhelming. great discussion by elena castro. exciting prostate day at #gu23 biomarkers or not biomarkers? hot topic in mcrpc. what do we think? '''### Response: The sentiment polarity expressed regarding the given aspect term talapro-2 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''noel clarke presenting propel os data #gu23 improvement in os of 7 months in itt population largely driven by hrrm pts need longer-term fu to see where os lands in hrrm vs non-hrr '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''final overall survival (os) in propel by noel clarke, frcs -trend toward os benefit with olaparib+abi in mcrpc!
-olaparib discontinuation 1/5 #gu23 #prostatecancer #medtwitter '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''os data from propel (olaparib + abi) in 1st line mcrpc. 7 mo median os benefit (p=0.054). but really driven by hrrm subgroup, right? #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel: important take home slide from on parpi role in mcrpc. brca>hrrm>all comers>non-hrrm #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''data on parpi are extremely complex and did a wonderful job putting it all into context! major issues of propel include ddr status, type of ddr mutation, effects in combination with arsi and line of therapy - much of which needs to be worked out. #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel trial: final os analysis patient selection remains the clue!
#gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' propel: i have little understanding of statistics but, wouldn't os only be positive if p<0.037? it's currently 0.054 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''updated survival data from propel in #mcrpc #prostatecancer is presented as positive #gu23 despite ci =/>1.0 the data in the non-mutated patients remains an issue, especially given toxicity of #parp inhibition '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''brilliant discussion about propel trial #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''looking forward to #gu23. great uk representation with and noel clarke among others presenting key clinical trial data. pace a. chhip. propel. '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hrr status matters!!!! propel at #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel study confirms a strong os signal in mcrpc all-comers. is data on post-progression therapy (i.e n of brca+ pts in control arm receiving olaparib) needed to understand the results? #gu23'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''final os analysis of propel: no significant benefit in itt, but more remarkable effect for hrrm. so everything comes back to the same point: should we test for hrr or not? #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term talapro-2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''amazing data presented from talapro-2 by on the heals of propel and magnitude providing future support of parpi + arsi. trials not powered for os so leaves some open questions. #gu23'''### Response: The sentiment polarity expressed regarding the given aspect term talapro-2 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel met its primary endpoint: statistically significant rpfs benefit in the itt population of patients with mcrpc treated with abiraterone + olaparib vs abiraterone + placebo. os trend observed with abiraterone + olaparib #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel met its primary endpoint: statistically significant rpfs benefit in the itt population of patients with mcrpc treated with abiraterone + olaparib vs abiraterone + placebo. os trend observed with abiraterone + olaparib #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term abiraterone in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel met its primary endpoint: statistically significant rpfs benefit in the itt population of patients with mcrpc treated with abiraterone + olaparib vs abiraterone + placebo. os trend observed with abiraterone + olaparib #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term abiraterone in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''very modest effet on os for non-hrr patients, better to give psma-lutetium for these patient...#ascogu23 #propel'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''noel clarke discussing rationale for ar inhibition and parp inhibitor and os results from propel. data overwhelming for hrr mutated patients, not quite so for non hrr group. let the debate begin! #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''final os for propel: abi + olap vs abi + pbo in 1l mcrpc #gu23 abi + olap vs abi + pbo: os: hr 0.81, 95% ci 0.67-1.00 (47.9% mature) os hrrm: hr 0.66, 95% ci 0.45-0.95 os non-hrrm: hr 0.89, 95% ci 0.70-1.14 tfst: hr 0.76, 95% ci 0.64-0.90 pfs2: hr 0.76, 95% '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''final pre-specificied os in propel study by prof noel clark: no significant benefit in itt population but nice results in hrrm #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel met its primary endpoint demonstrating a statistically significant rpfs benefit in the itt population of patients with mcrpc treated with abiraterone + olaparib vs abiraterone + placebo. os trend observed with abiraterone + olaparib #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel met its primary endpoint demonstrating a statistically significant rpfs benefit in the itt population of patients with mcrpc treated with abiraterone + olaparib vs abiraterone + placebo. os trend observed with abiraterone + olaparib #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term abiraterone in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#propel met its primary endpoint demonstrating a statistically significant rpfs benefit in the itt population of patients with mcrpc treated with abiraterone + olaparib vs abiraterone + placebo. os trend observed with abiraterone + olaparib #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term abiraterone in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''interesting os curve from propel with a separation after 22 months, coincident with the rpfs. is the post-progression therapy influencing this data? #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''dr. elena castro provides an excellent overview of #parp inhibitor propel data in #prostatecancer #gu23 providing the necessary context and caution (incluing using #pfs as a surrogate for survival) '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' and please don't say "trend" for propel data. if p value was 0.04, would you say "a trend towards insignificance"?'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' your comment is right. it's more a comment to the way the final analyses is being presented, pushing positivity a bit too much'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel final os data presented. os positive in the itt with signal in hrr positive and negative. more fireworks on stage about what to do for hrr- patients. #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''great discussion about hrr-mutated mcrpc in propel by at #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''noel clark #gu23 presents data on adding olaparib to abiraterone for first line crpc. quite different benefit profile appears to be the case for those with and without ddr mutations. '''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel trial data on abi plus olaparib in first line mcrpc. we are proud london-on participated on the trial. #gu23 #ascogu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is Neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#gu23 here are the awaited final results from propel trial in crpc #prostatecancer - met its primary endpoint in the itt population: abi + olaparib improves pfs. '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel met its primary endpoint demonstrating a statistically significant rpfs benefit in the itt population of patients with 1l mcrpc treated with abiraterone + olaparib versus abiraterone + placebo. not significant in os. #gu23 #prostatecancer '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel is a great trial. but it doesn't really seem right to highlight a "trend" in non-hrrm patients when the hr is 0.89 and ci including 1 and then some...'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''key unknowns from propel data #gu23 #prostatecancer 1. how many pts had mutations, but were not captured? and perhaps more importantly 2. for the hrrm patients, how many of them went on to receive parp inhibitor later on and how many did not? '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is Neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''yes, that could be a possibility for a small subgroup that propel truly benefit and mam s the differences in the km curves'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''propel - how much benefit is driven by brca vs all hrrm? how many brca/hrrm patients were allowed to cross-over to parpi?'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''hrr mutated 1l mcrpc trials like propel : -balance between side-effects and potential benefit depends on hrr status. -benefit in pfs # benefit in os.
nice conclusions by at #gu23 #sanfrancisco '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' pre-specified final os results of phase iii rct propel (abi + olaparib vs abi + placebo) in the 1l #mcrpc due to be presented by prof noel clarke at #ascogu2023 very soon! '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is Neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' pre-specified final os results of phase iii rct propel (abi + olaparib vs abi + placebo) in the 1l #mcrpc due to be presented by prof noel clarke at #ascogu2023 very soon! '''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''both propel and talapro2 show modest rpfs benefit (no os benefit so far) in patients with hrr-wt mcrpc. is it enough to justify toxicity and cost? jury is still out. combo approved in europe but not in us. #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term talapro2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''both propel and talapro2 show modest rpfs benefit (no os benefit so far) in patients with hrr-wt mcrpc. is it enough to justify toxicity and cost? jury is still out. combo approved in europe but not in us. #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term talapro2 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''excellent propel trial : abiraterone (abi) + olaparib(ola) vs abi and 1l pbo in patients with mcrpc, results were abi + wave prolonged os by > 7 m versus (abi+pbo) and the median os of > 42 m is the longest median reported to date in a phase 3 trial in 1 l #mcrpc. #asco #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' exactly. propel technically is negative'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''how to use parii? when?
which combination? all comers? only brcam?
#ascogu23 propel talapro2 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term talapro2 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''how to use parii? when?
which combination? all comers? only brcam?
#ascogu23 propel talapro2 '''### Response: The sentiment polarity expressed regarding the given aspect term talapro2 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''final os analysis in propel:
- rpfs -os trend observed
- longest os reported to date in 1l mcrpc #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' agree elena on propel. that why i said improvement and not significant improvement'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''do you think adding olaparib is justified in the hrrneg patients based on this data? taking into account the potential small benefit at the cost of increased toxicity by adding the drug.'''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term deucrava in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''thx for the post but i'm not sure about your phrasing... there is no relevant benefit in hrr neg, while you get years of added clinical and financial tox. in hrr+, there is a trend towards os benefit, but at great cost... would giving olaparib at progression do the same?'''### Response: The sentiment polarity expressed regarding the given aspect term deucrava in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''thx for the post but i'm not sure about your phrasing... there is no relevant benefit in hrr neg, while you get years of added clinical and financial tox. in hrr+, there is a trend towards os benefit, but at great cost... would giving olaparib at progression do the same?'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''gutted to miss #gu23 this year but pleased to see the high number and quality of work presented. this updated analysis on propel strengthens the argument to use parpi+arsi in mcrpc in hrrm patients! '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''asco gu 2023 day 1 take home: parpi's! 3) propel olaparib (parpi) + abiraterone improved rpfs vs abiraterone alone in 1st line mcrpc irrespective of hrr status #ascogu23 #ascogu2023 #ascogu '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term olaparib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''asco gu 2023 day 1 take home: parpi's! 3) propel olaparib (parpi) + abiraterone improved rpfs vs abiraterone alone in 1st line mcrpc irrespective of hrr status #ascogu23 #ascogu2023 #ascogu '''### Response: The sentiment polarity expressed regarding the given aspect term olaparib in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term abiraterone in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''asco gu 2023 day 1 take home: parpi's! 3) propel olaparib (parpi) + abiraterone improved rpfs vs abiraterone alone in 1st line mcrpc irrespective of hrr status #ascogu23 #ascogu2023 #ascogu '''### Response: The sentiment polarity expressed regarding the given aspect term abiraterone in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' you right about propel !'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''a big theme of propel and parpi in general is how to manage anemia and other toxicities. would love to see analyses and measures focused on the impact of anemia/cytopenias beyond the fact-p, and also transfusions, workup and health care utilization due to these ae s #ascogu23'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] ''' agreed on propel!'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is Neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''classic example of a skewed itt analysis driven by a small subgroup of patients gaining major benefits. Propel conclusions are debatable'''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term propel in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#ascogu23 final overall survival (os) in propel: abiraterone (abi) and olaparib (ola) versus abiraterone and placebo (pbo) as first-line (1l) therapy for metastatic castration-resistant prostate cancer (mcrpc). '''### Response: The sentiment polarity expressed regarding the given aspect term propel in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cosmic313 cabo/ipi/nivo vs ipi/nivo in 1st line rcc. fu & numbers show continued strong pfs signal:hr 0.74.exploratory analysis show benefit for triplet mainly in intermediate risk .this is not due to drug exposure. maybe vegf treatment active in poor risk #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic313 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cabozantinib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cabozantinib plus nivolumab and ipililumab improves pfs in advanced rcc subgroups #urology #urologist #gu23 #kidneycancer '''### Response: The sentiment polarity expressed regarding the given aspect term cabozantinib in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term nivolumab in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cabozantinib plus nivolumab and ipililumab improves pfs in advanced rcc subgroups #urology #urologist #gu23 #kidneycancer '''### Response: The sentiment polarity expressed regarding the given aspect term nivolumab in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term ipilimumab in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cabozantinib plus nivolumab and ipililumab improves pfs in advanced rcc subgroups #urology #urologist #gu23 #kidneycancer '''### Response: The sentiment polarity expressed regarding the given aspect term ipilimumab in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''outcomes by imdc risk in the cosmic313 phase 3 trial evaluating cabozantinib + nivo and ipi in first-line advanced #rcc of imdc intermediate or poor risk. presented by . #gu23 written coverage by > '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cabozantinib in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cabozantinib plus nivolumab and ipilimumab shows notable pfs improvement in intermediate-risk, advanced rcc #gu23 #kcsm #oncology '''### Response: The sentiment polarity expressed regarding the given aspect term cabozantinib in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term nivolumab in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cabozantinib plus nivolumab and ipilimumab shows notable pfs improvement in intermediate-risk, advanced rcc #gu23 #kcsm #oncology '''### Response: The sentiment polarity expressed regarding the given aspect term nivolumab in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term ipilimumab in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cabozantinib plus nivolumab and ipilimumab shows notable pfs improvement in intermediate-risk, advanced rcc #gu23 #kcsm #oncology '''### Response: The sentiment polarity expressed regarding the given aspect term ipilimumab in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term COSMIC-313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''COSMIC-313 pfs benefit -50% any dose reductions
-70% g3-4 aes
-os not yet
#gu23 #medtwitter #kidney '''### Response: The sentiment polarity expressed regarding the given aspect term COSMIC-313 in the given tweet is positive |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''stellar presentation by update on cosmic313 #gu23 pfs hr 0.74 when added cabo to ipi/nivo in all-comers pfs hr 0.68 in interm risk, no diff in exposure to explain follow-up for os ongoing '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term COSMIC-313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''outstanding update of COSMIC-313 by ...still missing the explanation the high vs intermediate risk group dirences! ? #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term COSMIC-313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''triplet therapy in 1l rcc? provides an update on cosmic313 nivo/ipi +/- cabo #gu23: pfs hr 0.74 when added cabo to ipi/nivo in all-comers pfs hr 0.68 in interm risk, no diff in exposure to explain not a regimen for use outside trial at this time, os pending '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic313 in the given tweet is negative |
### Instruction: What sentiment polarity is expressed regarding the given aspect term COSMIC-313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''kicking off day 3 at #gu23 with an update on COSMIC-313 study data presented by from '''### Response: The sentiment polarity expressed regarding the given aspect term COSMIC-313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''it makes sense that the additive benefit of vegf to io therapy is less in imdc poor risk individuals with #rcc. good to know it wasn t due to poor tolerability in this group. #gu23 cosmic313 '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''#gu23 while pts w/ intermediate imdc risk group still show benefit from cosmic313 we hope to understand the poorer outcomes in poor risk group through rna-seq #cosmic313 '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic-313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''very interesting presentation from on comic-313, showing continued pfs benefit with triplet nivo+ipi+cabo, but surprisingly not clear benefit in imdc poor risk, despite similar drug exposure and similar toxicity. #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic-313 in the given tweet is neutral |
### Instruction: What sentiment polarity is expressed regarding the given aspect term cosmic-313 in the given tweet delimited by triple quotes? Answer from the options [\"positive\", \"negative\", \"neutral\"] '''cosmic-313 cabo+nivo+ipi (c+n+i) first line rcc intermediate or poor risk presentation , triplet therapy pfs was improved hr 0.63 in intermediate risk pt, but not poor risk pts. grade 3/4 trae occurred in 74% triplet therapy c+n+i patients vs 42% in p+n+i #gu23 '''### Response: The sentiment polarity expressed regarding the given aspect term cosmic-313 in the given tweet is neutral |