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828,691
Given the text:come check out qol research from phase 3 LUCENT induction & maintenance trials in moderately to severely active #uc #ulcerativecolitis on sunday from 5-7pm at #acg2022 , what is the sentiment for aspect term LUCENT in the sentence?
neutral
828,492
Given the text:conference by powles md showing us the cosmic-313 study, c+n+i improved pfs vs p+n+i in first-line arcc of imdc intermediate or poor risk; subgroup analysis suggested that the benefit was primarily in intermediate risk pts and comment that follow-up for os is ongoing #ascogu2023 , what is the sentiment for aspect term COSMIC-313 in the sentence?
neutral
829,135
Given the text:lipoproteins or stemi not your jam? never fear, has empa-kidney in #aha22 lbs5. empa-kidney: empagliflozin a win for patients with ckd , what is the sentiment for aspect term empagliflozin in the sentence?
positive
829,336
Given the text:no difference between #torsemide versus #furosemide in reduction of primary or secondary endpoints in the transform-hf trial #aha22 , what is the sentiment for aspect term transform-hf in the sentence?
neutral
829,119
Given the text:interesting discussion following the results of dcp. was the study biased to patients responsive to hctz? #aha22 , what is the sentiment for aspect term dcp in the sentence?
neutral
829,473
Given the text:$sln - silence therapeutics presents new analysis from SLN360-001 phase 1 single dose study in high lipoprotein(a) at the american heart association (aha) 2022 annual meeting , what is the sentiment for aspect term SLN360-001 in the sentence?
neutral
828,862
Given the text:david preiss presenting results of empa-kidney trial #aha22 , what is the sentiment for aspect term empa-kidney in the sentence?
neutral
828,584
Given the text:#aad2023 - #ucb presented positive results from two phase 3 studies evaluating bimekizumab efficacy and safety in treating moderate to severe #hidradenitissuppurativa (hs) in adults. #pharma #pharmaceutical #healthcare #dermatology #aad23 news media, what is the sentiment for aspect term bimekizumab in the sentence?
neutral
829,317
Given the text:empagliflozin and left ventricular remodeling in people without diabetes: primary results of the EMPA-HEART 2 cardiolink-7 randomized clinical trial | circulation , what is the sentiment for aspect term EMPA-HEART 2 in the sentence?
neutral
828,501
Given the text:sustained benefits of #mitraclip over 5-y fup & benefitial effect of crossover after 2y in #coapt trial #acc2023 #lbcts , what is the sentiment for aspect term coapt in the sentence?
positive
828,389
Given the text:the #oncoalerttoptweet for day1 #gi23 tweet gives accelerated approval of tucatinib in combo w/trastuzumab for previously treated ras wt her2- met #colorectalcancer 1 st fda approved tx in her2 met #crc , what is the sentiment for aspect term tucatinib in the sentence?
neutral
828,711
Given the text: i think reasonable in a phase 2 , vega is presented, what is the sentiment for aspect term vega in the sentence?
neutral
828,879
Given the text:novel CRISPR-ATTR -editing therapy shows promise for patients with transthyretin amyloid #cardiomyopathy #aha22 #heartfailure , what is the sentiment for aspect term CRISPR-ATTR in the sentence?
positive
829,482
Given the text:$sln silence therapeutics presents new analysis from SLN360-001 phase 1 single dose study in high lipoprotein(a) at the american heart association (aha) 2022 annual meeting 45 seconds delayed., what is the sentiment for aspect term SLN360-001 in the sentence?
neutral
829,420
Given the text:ISCHEMIA-extend aha22 survival after invasive or conservative management of stable coronary disease , what is the sentiment for aspect term ISCHEMIA-extend in the sentence?
neutral
828,789
Given the text:#aha22 #lbct ironman aim: to evaluate longer-term effects of intravenous fe on cve in patients w/ #hf lvef<45%, transferrin sat<20% or ferritin<100 g/l rct fe uc lower risk for heart failure + cardiovascular death with fe , what is the sentiment for aspect term ironman in the sentence?
neutral
829,167
Given the text: #aha22 #lbct interview dr gregory piazza spoke with ' dr about #prevent_hd watch here #rivaroxaban did not reduce a composite of venous and arterial thrombotic events, hospitalisation and death in pts with covid-19 , what is the sentiment for aspect term rivaroxaban in the sentence?
negative
828,727
Given the text:transform-hf summary results from #aha22 shows commendable efficacy in pts, what is the sentiment for aspect term transform-hf in the sentence?
positive
829,491
Given the text: esc tv on the road to #aha22, get the best of what was presented on transform-hf and ironman in a nutshell! , what is the sentiment for aspect term transform-hf in the sentence?
neutral
828,385
Given the text:here we go, the $alpmy zolbetuximab #gi23 late-breaking abstract is live , what is the sentiment for aspect term zolbetuximab in the sentence?
neutral
828,641
Given the text:TL thinks for CM-816 combining IO with is the new SOC and will almost certainly improve OS in early-stage disease. He added that neoadjuvant IO has a multiple theoretical advantages over adjuvant, what is the sentiment for aspect term CM-816 in the sentence?
positive
829,193
Given the text:the PRECISION trial showed that dual antagonism of the endothelin receptor improves blood pressure control in patients with resistant #hypertension. learn more: #aha22 #cardiotwitter , what is the sentiment for aspect term PRECISION in the sentence?
positive
829,415
Given the text:$cytk cytokinetics presents new data for GALACTIC-HF at the american heart association scientific sessions 2022 , what is the sentiment for aspect term GALACTIC-HF in the sentence?
neutral
828,898
Given the text: nearly 20 years later in a population on statin, jelis results are confirmed: 19-21% rrr w/ epa 1800 mg. hscrp similar effect in reduce-it, real. magnitude . probably 15-20% rrr af real pcsk9i rrr is 15% 5/5 #aha22 #epa #om3 , what is the sentiment for aspect term reduce-it in the sentence?
neutral
828,702
Given the text:promising combination trial results in vega: tnf (gol) vs il-23 (gus) vs combo induction > gus. combo > mono for induction. later time pt combo >gus > gol. trying to raise the ceiling. #acg2022 , what is the sentiment for aspect term vega in the sentence?
positive
828,425
Given the text:my goodness! a new doublet option in mcrpc #prostatecancer - parpi plus nht, by noel clarke #gu23 .propel study has better overall survival benefit of 7mo very high in this setting. new standard of care? #pcsm , what is the sentiment for aspect term propel in the sentence?
positive
828,847
Given the text:as we saw from the earlier press release, now presented #aha22 and published - no cv event reduction from pemafibrate v placebo , what is the sentiment for aspect term pemafibrate in the sentence?
neutral
828,382
Given the text:and now tislelizumab plus chemo showed better os, pfs and orr in pts with gastric cancers or gej adenoc and pd-l1 score >5% .. love this meeting #gi23 #asco , what is the sentiment for aspect term tislelizumab in the sentence?
positive
828,990
Given the text:pro-hf sub-study: routine kccq-12 assessments in hf improves accuracy of provider assessment of patient health status. written by ! summary and analysis and more #aha2022 coverage below: , what is the sentiment for aspect term pro-hf in the sentence?
positive
829,220
Given the text:thank you so much for thoughtful discussion of BRIGHT-4 & highlighting the consistency w ipd-ma presented earlier today. #stemi #anticoagulation #bivalirudin #heparin , what is the sentiment for aspect term BRIGHT-4 in the sentence?
neutral
828,436
Given the text:updated survival data from propel in #mcrpc #prostatecancer is presented as positive #gu23 despite ci =/>1.0 the data in the non-mutated patients remains an issue, especially given toxicity of #parp inhibition , what is the sentiment for aspect term propel in the sentence?
negative
829,122
Given the text:bruce neal talking about the population impact of the findings of the landmark SSaSS trial. #bloodpressure #salt , what is the sentiment for aspect term SSaSS in the sentence?
neutral
828,518
Given the text:#coapt 5 year data #lbct presented by at #acc23. benefit in mr reduction, heart failure hospitalization, and qol out to 5 years. pts who crossed over from control to device also saw similar benefit! , what is the sentiment for aspect term coapt in the sentence?
positive
828,532
Given the text:secondary outcomes for coapt mitraclip + gdmt vs. gdmt: all-cause : 29.1% vs. 46.1%, hr 0.62, 95% ci 0.46-0.82, p < 0.001 or hf : 45.7% vs. 67.9%, p < 0.001 cv : 29.1% vs. 46.1%, p < 0.001 #acc23, what is the sentiment for aspect term coapt in the sentence?
Neutral
829,377
Given the text:will CRISPR-ATTR based in vivo genome editing in humans be the next therapeutic generation for ttr amyloidosis? amazing data from dr. julian gillmore, ntla-2001 #aha22 , what is the sentiment for aspect term CRISPR-ATTR in the sentence?
neutral
828,639
Given the text:AACR22: Additional questions surrounding the use of adjuvant treatment for patients from CM-816 and would that have additional benefit in patients even those with pCR , what is the sentiment for aspect term CM-816 in the sentence?
neutral
828,361
Given the text:the long awaited SWOG 1815 results are now online. gap vs gc for biliary tract cancers. come hear present the results at 1 pm today. #gi23 , what is the sentiment for aspect term SWOG 1815 in the sentence?
neutral
828,441
Given the text:final os analysis of propel: no significant benefit in itt, but more remarkable effect for hrrm. so everything comes back to the same point: should we test for hrr or not? #gu23 , what is the sentiment for aspect term propel in the sentence?
positive
829,074
Given the text: agree, great work on transform-hf! congratulations., what is the sentiment for aspect term transform-hf in the sentence?
neutral
828,485
Given the text:#gu23 terrific talk from on subgroups from cosmic313 - pfs benefit of triplet maintained hr 0.74 in all pts and 0.68 in intermediate follow-up for os ongoing , what is the sentiment for aspect term cosmic313 in the sentence?
neutral
829,430
Given the text:does tongxinluo, a chinese herbal medicine, offer benefit in stemi patients? interesting finding in the CTS-AMI trial presented at #aha22 suggest major benefit. what is the working mechanism? and... can we make it vegan? let's dive into this paper once it is published. , what is the sentiment for aspect term CTS-AMI in the sentence?
neutral
829,418
Given the text:$cytk cytokinetics presents new data for GALACTIC-HF at the american heart association scientific sessions 2022 , what is the sentiment for aspect term GALACTIC-HF in the sentence?
neutral
828,623
Given the text:CM-816 Surgeons and patients have a need to operate especially in the stage I and II. , what is the sentiment for aspect term CM-816 in the sentence?
neutral
829,093
Given the text: tomorrow at 330 we will do a deep dive to prominent #aha22 join us and ask questions , what is the sentiment for aspect term prominent in the sentence?
neutral
828,458
Given the text:key unknowns from propel data #gu23 #prostatecancer 1. how many pts had mutations, but were not captured? and perhaps more importantly 2. for the hrrm patients, how many of them went on to receive parp inhibitor later on and how many did not? , what is the sentiment for aspect term propel in the sentence?
Neutral
828,880
Given the text:ironman for a broad range of patients with #heartfailure ( #lvef 45%) and fe deficiency, iv ferric derisomaltose was associated with a risk of admissions for hf and cv #aha22 , what is the sentiment for aspect term ironman in the sentence?
neutral
828,240
Given the text:but at least in msi-h or dmmr patients, cr rates were excellent in the neonipiga and infinity trial. if it is supported by phase 3 studies, it will be the new standard. #gi23 , what is the sentiment for aspect term infinity in the sentence?
positive
828,351
Given the text:swog 1815 gap vs gp unfortunately negative. gallbladder and locally advanced disease may derive more benefit from triplet therapy. #gi23 , what is the sentiment for aspect term SWOG 1815 in the sentence?
negative
828,937
Given the text:looks like #bypasssurgery scored a knockout versus #endovascular therapy in #clti for the following outcomes death, reinterventions & male best-cli , what is the sentiment for aspect term best-cli in the sentence?
neutral
829,190
Given the text:areef ishani presenting dcp #aha22 , what is the sentiment for aspect term dcp in the sentence?
neutral
829,367
Given the text:ecmo-cs trial: immediate implementation of va-ecmo in patients with rapidly deteriorating or severe cardiogenic shock did not improve clinical outcomes compared with an early conservative strategy. #aha22 , what is the sentiment for aspect term ecmo-cs in the sentence?
negative
828,680
Given the text:On CM-816 AACR data release:TL said she was having a lot of hope in this trial and she is not disappointed by the results. TL said, of course, the OS data are to mature, but she think the results of pCR and EFS justify to consider nivo+chemo as SOC. TL stated that she need to take the time to have a deeper look on population and subgroup. TL would like to get access by BMS to this option. TL think there is a need for physicians to get prepared to use nivo+CT in this setting. TL explains that neoadjuvant treament is rarely use in her region and that there will be a need for mentality changes, ways of working to be reviewed., what is the sentiment for aspect term CM-816 in the sentence?
positive
828,902
Given the text:happening now at #ress22: prof presenting the box trial: devise-based prevention of fever for up to 36 or 72 hours after ohca. , what is the sentiment for aspect term box in the sentence?
neutral
829,384
Given the text:our stop team under mentoship!. more is coming to the #yescct and plaque quantification field. #aha22 , what is the sentiment for aspect term stop in the sentence?
neutral
828,556
Given the text: i think the coapt trial required 90 days of stable meds prior to enrollment, so 3 months seems reasonable., what is the sentiment for aspect term coapt in the sentence?
neutral
828,887
Given the text:#ecls as circulatory support in cs? results of ecmo-cs out! immediate #ecmo-cs feasible but no improved outcomes in rapidly deteriorating/severe cs (scai d-e) vs early conservative therapy allowing ecmo if worsening hemodynamics #foamcc #aha2022 , what is the sentiment for aspect term ecmo-cs in the sentence?
neutral
828,948
Given the text:#aha22 late-breaking rct: best-cli trial comparing surgical vs endovascular revascularization. two cohorts were randomized. one cohort with adequate gsv conduit. another cohort without gsv conduit. male was a key primary outcome. , what is the sentiment for aspect term best-cli in the sentence?
neutral
829,211
Given the text:talk of the day after late breaking transform-hf trial, the one and only dr. managed to chat with him in between sessions (lucky me!). what a legend! #aha22 , what is the sentiment for aspect term transform-hf in the sentence?
neutral
828,866
Given the text:ecmo-cs in patients with rapidly deteriorating or severe cardiogenic shock, immediate use of #ecmo does not improve outcomes over an initially conservative strategy with bailout ecmo as needed #aha22 #heartfailure #cardiotwitter , what is the sentiment for aspect term ecmo-cs in the sentence?
negative
828,871
Given the text:ecmo-cs in the therapy of cardiogenic shock: results of the ecmo-cs rct primary endpoint from any cause, resuscitated circulatory arrest, and use of another #mcs device at 30 days did not differ between the immediate versus conservative groups (63.8% vs 71.2%; p= 0.21) #aha22 , what is the sentiment for aspect term ecmo-cs in the sentence?
neutral
829,462
Given the text:silence therapeutics presents new analysis from SLN360-001 phase 1 single dose study in high lipoprotein(a) at the american heart association (aha) 2022 annual meeting - , what is the sentiment for aspect term SLN360-001 in the sentence?
neutral
829,395
Given the text:hls therapeutics highlights key data on the late breaking RESPECT-EPA study presented at the american heart associat , what is the sentiment for aspect term RESPECT-EPA in the sentence?
neutral
829,034
Given the text:acc medical correspondent dr. discusses points from #aha22's lbct results from the sport trial comparing rosuvastatin & 6 dietary supplements in pts at risk of #ascvd w/ drs. steve nissen & luke laffin as part of #accesspoints. #jacc , what is the sentiment for aspect term sport in the sentence?
neutral
828,884
Given the text:PROGRESSIVE-AF first-line #ablation reduces #afib progression, boosts #qol patient-reported outcomes, including disease-specific and general #qol and symptom burden, also significantly favored an ablation-first strategy #aha22 , what is the sentiment for aspect term PROGRESSIVE-AF in the sentence?
positive
829,251
Given the text: tude positive COACH #aha22, what is the sentiment for aspect term COACH in the sentence?
positive
828,795
Given the text: no both men and women. but not enough women in my opinion. 300 (26%) were women in ironman #aha22 , what is the sentiment for aspect term ironman in the sentence?
neutral
828,920
Given the text:really proud moment for me today, presenting 1st time in a featured science session . deeper insight in advor trial with key contributions from among many others. proudly ! tweetorial below! , what is the sentiment for aspect term advor in the sentence?
neutral
828,816
Given the text:PROGRESSIVE-AF first-line ablation initial aad for afib shows lower progression to persistent afib 1.9% 7.4% lower af burden better 3 yr qol by 2 scores hospitalisation 5.2% vs.16.8% rrr 69% cardioversions ns #aha22 , what is the sentiment for aspect term PROGRESSIVE-AF in the sentence?
positive
829,348
Given the text:new standard for #heartfailure treatment set by and team: early and fast uptitration of #gdmtworks is feasible, safe and improves outcomes in strong-hf. presented today at #aha22 and simultaneously published in : , what is the sentiment for aspect term strong-hf in the sentence?
positive
828,763
Given the text:CRISPR-ATTR summary results at #aha22 , what is the sentiment for aspect term CRISPR-ATTR in the sentence?
neutral
829,298
Given the text:results of the transform-hf trial presented at aha 22 indicate there were no significant differences in rate of all-cause mortality or hospitalization with the use of torsemide compared with furosemide in people with heart failure. #aha22 #heartfailure, what is the sentiment for aspect term transform-hf in the sentence?
neutral
828,779
Given the text:questions that remain #rapco #aha22. #lbct , what is the sentiment for aspect term rapco in the sentence?
neutral
828,987
Given the text:"small interfering rna to reduce lipoprotein(a) in cardiovascular disease in OCEAN(a)-DOSE trial." pr sent l'#aha22 et publi dans le . #medtwitter #cardiotwitter , what is the sentiment for aspect term OCEAN(a)-DOSE in the sentence?
positive
829,398
Given the text:ironman with the bayesian approach and longitudinal ordinal analysis would provide better power and be easier to interpret clinically. forcing a "dichotomous" decision within a null-hypothesis-testing framework with cis 0,66 - 1,02 does not serve us well... , what is the sentiment for aspect term ironman in the sentence?
positive
828,723
Given the text:#ecco2022 op10 #antitnfs remain more efficient in achieving mucosal healing in both ileum and colon in #crohns as compared to ust and vdz. meta analysis from rcts., what is the sentiment for aspect term op10 in the sentence?
positive
828,334
Given the text:SWOG 1815 is an important negative 1l btc study #gi23 -ph2 gcn mos 19m -ph3 gcn mos 14m with no significant difference to gc standard w/ toxicity thanks to etal for reminding us why we need to do phase 3 trials even in uncommon cancers , what is the sentiment for aspect term SWOG 1815 in the sentence?
neutral
829,259
Given the text:#aha2022 . great oral poster presentation. socioeconomic status, heart failure and aric prediction. way to go dr mathews , what is the sentiment for aspect term aric in the sentence?
positive
828,802
Given the text:some additional slides from RESPECT-EPA including patient flow-diagram, baseline characteristics, study limitations, and concluding thoughts #aha22 , what is the sentiment for aspect term RESPECT-EPA in the sentence?
neutral
828,981
Given the text:no benefits of pemafibrate at #aha22 , what is the sentiment for aspect term pemafibrate in the sentence?
negative
829,102
Given the text: i meant to say hi to you, but i dont think our paths crossed post OCEAN(a)-DOSE presentation!, what is the sentiment for aspect term OCEAN(a)-DOSE in the sentence?
neutral
829,130
Given the text:great catching up with and looking forward to late-breaking science presentations from advor by and at #aha22 today! , what is the sentiment for aspect term advor in the sentence?
neutral
829,277
Given the text:paulkalra to deliver long awaited ironman trial #heartfailure #parenteraliron #aha22 , what is the sentiment for aspect term ironman in the sentence?
neutral
828,445
Given the text:final os for propel: abi + olap vs abi + pbo in 1l mcrpc #gu23 abi + olap vs abi + pbo: os: hr 0.81, 95% ci 0.67-1.00 (47.9% mature) os hrrm: hr 0.66, 95% ci 0.45-0.95 os non-hrrm: hr 0.89, 95% ci 0.70-1.14 tfst: hr 0.76, 95% ci 0.64-0.90 pfs2: hr 0.76, 95% , what is the sentiment for aspect term propel in the sentence?
neutral
828,631
Given the text:In the SWOG-MAP S1400I - Patients achieving objective response had higher IL4 and LAMP3 and lower IL6 and IL8 at baseline and week 3 compared to non-responders, what is the sentiment for aspect term SWOG-MAP S1400I in the sentence?
neutral
829,033
Given the text: thanks - did many clinicians continue acetazolamide for longer in #advor or do they in real-world practice?, what is the sentiment for aspect term acetazolamide in the sentence?
neutral
829,109
Given the text:more data form REVIVED-BCIS2 no difference in all-cause death or sudden death with pci vs omt #aha22 , what is the sentiment for aspect term REVIVED-BCIS2 in the sentence?
neutral
828,636
Given the text:During the CODEBREAK-100 discussant presentation the TL stated that he would prioritize PDL1 therapy over KRAS therapy if the patient had high PDL1 therapy, high TMB, high TILs, and wild type STK11/KEAP1., what is the sentiment for aspect term CODEBREAK-100 in the sentence?
neutral
829,005
Given the text:#aha2022: fantastic presentation by of the positive strong-hf trial publication today in cocorico dream team , what is the sentiment for aspect term strong-hf in the sentence?
neutral
829,388
Given the text: not surprising at all considering upto 65-80% of na reabsorbed in proximal tubule in advor. understanding pathophysiology=desirable outcomes!, what is the sentiment for aspect term advor in the sentence?
neutral
829,267
Given the text: ecmo-cs mrct on immediate #ecmo vs early conservative therapy (ecmo used for further deterioration) in 117 pts with cardiogenic shock ( 3rd fig) no difference in the 30-day composite primary outcome or mortality #foamcc #aha2022 #cardiotwitter , what is the sentiment for aspect term ecmo-cs in the sentence?
neutral
828,881
Given the text:#originalresearch simpub #aha2022 #circaha22: the efficacy and safety of empagliflozin was similar in black and white patients with hf across the range of ef, with a suggestion of enhanced efficacy in black patient... , what is the sentiment for aspect term empagliflozin in the sentence?
neutral
828,851
Given the text:large empa-kidney meta-analysis highlights safety/efficacy of #sglt2 inhibitors in reducing risk of kidney disease progression, acute kidney injury, cv death & #heartfailure hospitalization in patients w/ #ckd or hf, irrespective of #diabetes status #aha22 , what is the sentiment for aspect term empa-kidney in the sentence?
positive
829,199
Given the text: thank you dr & prof for sharing the insights from strong-hf watch here rapid up-titration of #gdmt under close follow-up is safe and reduces the risk of #hf readmission and all-cause mortality at 180 days! #aha22 , what is the sentiment for aspect term strong-hf in the sentence?
positive
828,964
Given the text:detailed analysis about the prominent trial by - fibrates do not show cardiovascular benefits , what is the sentiment for aspect term prominent in the sentence?
negative
828,922
Given the text:hearing various wrong conclusions at #aha22 post prominent: "we can ignore tg" "tg doesn't matter" reminder: when tg (esp w/ dm or hdl) focus should be on even more aggressive ldl-c (also as more atherogenic ldl particles), dm rx, weight loss / lifestyle changes , what is the sentiment for aspect term prominent in the sentence?
neutral
828,337
Given the text:SWOG 1815 inspiring shows no value of adding nabp to standard gem-cis in adv biliary cancers in 1815. , what is the sentiment for aspect term SWOG 1815 in the sentence?
neutral
829,043
Given the text:a novel CRISPR-ATTR -based gene-editing technique seems to safely diminish the production of a protein linked to worsening outcomes in patients with transthyretin amyloidosis cardiomyopathy, according to first-in-human data. #aha22, what is the sentiment for aspect term CRISPR-ATTR in the sentence?
positive
828,645
Given the text:NTL shared that he prefers CM-816 survivals as a metric of success over median OS especially IO therapy because of the MOA of these agents, what is the sentiment for aspect term CM-816 in the sentence?
positive
828,741
Given the text:prominent summary results at #aha22 , what is the sentiment for aspect term prominent in the sentence?
neutral
829,310
Given the text:and now up is empa-kidney #aha22 in main 1 please submit questions on the aha conferences app , what is the sentiment for aspect term empa-kidney in the sentence?
neutral