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80e16084-d58b-4584-8712-feb0dda14e36
GNAS-1遺伝子変異は関連しています
線維性骨異形成
骨形成不全
エナメル質形成不全
鎖骨頭蓋異形成
0
single
Fibrous dysplasia is caused by a mutation in GNAS1 gene.
Pathology
null
GNAS-1 gene mutation is associated with
Fibrous dysplasia
Osteogenesis imerfecta
Amelogenesis imperfect
Cleidocranial dysplasia
5c659945-dd4a-4dbb-ac72-ef8136de66d9
ステップバック法は次のように構成されています:
2つのフェーズ。
3つのフェーズ。
4つのフェーズ。
なし。
0
multi
step back technique has 2 phases. Phase 1 is apical preparation phase. Phase 2 stepping back phase.
Dental
null
Step back technique is consist of:
2 phases.
3 phases.
4 phases.
None.
19c5be03-cef6-472d-b075-e9a38c53e5f4
強直性脊椎炎に特有なのは本当ですか?
HLA
B27
仙腸関節炎
赤血球沈降速度の上昇
2
multi
Answer- C. Sacroileitis
Surgery
null
Specific for Ankylosing spondylitis is true?
HLA
B27
Sacroileitis
Raised ESR
a4ae6ca7-78a0-48fd-956c-4259c141d158
男性が失語症で来院しました。物の名前を言うことができず、復唱も苦手です。しかし、理解力、流暢さ、書かれた言葉の理解には影響がありません。彼はおそらく何の病気にかかっていますか?
健忘失語症
ブローカ失語症
超皮質性感覚失語症
伝導失語症
3
single
Ans: D. Conduction aphasia(Ref Harrison 19/e p 1 76, 18/e p302)Typical case of conduction aphasia with normal comprehension & fluency, but impaired naming & repetition.Conduction aphasia:Due to damaged arcuate fasciculus.Arcuate fasciculus:Connection between Wernicke's (language comprehension) & Broca's (Language production) areas.Hence, connection lost.Clinical features:Hallmark finding - Inability to repeat words.Comprehension & language expression intact.Inability to transfer understood word to Broca 's area to be expressed.Results in meaningful fluent speech & relatively good comprehension but very poor repetition.
Medicine
null
A man comes with aphasia. He is unable to name things and repetition is poor. However comprehension, fluency and understanding written words is unaffected. He is probably suffering from:
Anomic aphasia
Broca's aphasia
Transcoical sensory aphasia
Conduction aphasia
857b4f18-59a4-4f38-923e-679808197235
3混合ペーストでは、何の存在によって変色が起こりますか?
シプロフロキサシン
ミノサイクリン
メトロニダゾール
テトラサイクリン
1
single
null
Dental
null
In 3 mix paste; discoloration occurs due to presence of:
Ciprofloxacin
Minocycline
Metronidazole
Tetracycline
0e7917ea-310b-4477-9897-f4901f728448
次のリポタンパク質のうち、電気泳動で帯電した端に移動しないものはどれですか?
VLDL(超低密度リポタンパク質)
LDL
HDL
カイロミクロン
3
single
Based on electrophoretic separation from cathode to anode, the order of lipoprotein in an electrophoretogram is  Chylomicron LDL (β Lipoprotein) VLDL (Pre β Lipoprotein) IDL (Broad β Lipoprotein) HDL (α Lipoprotein)
Biochemistry
null
Which of the following lipoproteins does not move towards charged end in electrophoresis?
VLDL
LDL
HDL
Chylomicrons
b02a2fb8-3cd5-4043-88fa-ab4ad3092efe
根尖周囲組織の炎症は何によって持続されますか?
停滞した組織液
壊死組織
微生物
膿細胞
2
single
Apical periodontitis is a chronic inflammatory disorder of periradicular tissues caused by aetiological agents of endodontic origin.  Persistent apical periodontitis occurs when root canal treatment of apical periodontitis has not adequately eliminated the intraradicular infection (microbes).
Dental
null
Inflammation of the periapical tissue is sustained by:
Stagnant tissue fluid
Necrotic tissue
Microorganisms
Pus cells
1f8a97a5-64cf-4635-a50a-e84ac5a0d7f1
播種性悪性腫瘍の患者が、悪心、嘔吐、意識障害を伴って緩和ケアクリニックに来院しました。検査で高カルシウム血症が検出されました。最初の治療方針は何ですか?
静脈内ステロイド
サイアザイド
静脈内輸液
静脈内ビスホスホネート
2
multi
Ans: C. Intravenous fluids(Ref: Harrison 19/e p314; 18Ie p361)Management of Significant, Symptomatic Hypercalcemia:Initial therapy:Volume expansion (hypercalcemia leads to dehydration) with 4-6 L of IV saline over first 24 h, keeping in mind that underlying comorbidities (e.g., congestive hea failure) may require use of loop diuretics to enhance Na+ & Ca+ excretion.Increased calcium mobilization from bone (in malignancy or severe hyperparathyroidism).Drugs that inhibit bone resorption should be considered.Zoledronic acid, pamidronate & ibandronate - In treatment of hypercalcemia of malignancy in adults.Onset of action is within 1-3 days, with normalization of serum calcium levels occurring in 60-90% of patients.
Medicine
null
A patient of disseminated malignancy comes to the palliative care clinic with nausea, vomiting and altered sensorium. Hypercalcemia is detected on investigations. What will be the first line of management?
Intravenous steroids
Thiazides
Intravenous fluids
Intravenous bisphosphonates
8db7e145-052a-4774-9a5f-db3c4e9ac1d6
建物の崩壊後、残骸の中である人の上腕骨の長さが24.5 cmです。この人の推定身長はどれくらいですか?
90 cm
110 cm
130 cm
146 cm
2
single
Ans: C. 130 cm(Ref Parikh 6/e p2.75, 12.2).In general, humerus represents 20%, Tibia 22%, Femur 27% and Spine 34% of the stature.Multiplication factor for humerus is 5.31 for calculation of stature.In the question, length of femur is 24.5 cm.Hence, predicted height = 5.31x24.5 = 130 cm.
Forensic Medicine
null
After a building collapse, among remnants, a person's length of humerus is 24.5 cm. What is the predicted height of this person?
90 cm
110 cm
130 cm
146 cm
2fb9aa7b-5106-4856-943d-f6554959feab
狂犬病ワクチンを接種してはいけない場合は?
ネズミに噛まれた場合
猫に噛まれた場合
犬に噛まれた場合
サルに噛まれた場合
0
single
null
Microbiology
null
Rabies vaccine not to be given in case of?
Rat bite
Cat bite
Dog bite
Monkey bite
acfc14d7-1051-4939-9631-c1910b58c295
舌が赤紫色で口角にひび割れが見られるのは、何の欠乏症ですか?
ビタミンB1
ナイアシン
リボフラビン
パントテン酸
2
single
null
Pathology
null
Magenta tongue and cracks at corner of mouth are seen in deficiency of:
Vitamin B1
Niacin
Riboflavin
Pantothenic acid
7dbd5a5b-1731-4cbd-a3e1-f50c0db1e695
上顎第一大臼歯の口蓋根の最も一般的な湾曲は何ですか?
顔面側
舌側
遠心
近心
0
single
null
Dental
null
The most common curvature of the palatal root of maxillary first molar is:
Facial
Lingual
Distal
Mesial
6dfdea6c-4c96-49dc-8b65-a57b59d87036
次のうち、どの泣き声が大きく、高音でサイレンのような泣き声で特徴づけられますか:
頑固な泣き声。
恐怖の泣き声。
痛みの泣き声。
代償性の泣き声。
0
single
null
Dental
null
Which of the following cry is characterized by loud, high pitched and siren-like wail:
Obstinate cry.
Frighten cry.
Hurt cry.
Compensatory cry.
75394ad7-5dde-4b6b-8cec-7365972b5dd6
フッ化物ピットおよびフィッシャーシーラントはどの世代に属しますか?
I世代
II世代
第III世代
第IV世代
3
single
TYPES OF PIT AND FISSURE SEALANTS 1. Based on curing method: First generation: Polymerized with ultraviolet light of 350 nm wavelength.  Absorbs UV light excessively and prevents complete polymerization of the sealant.  Light intensity varies from lamp to lamp. Second generation: Self-cured or chemically cured.  Most of them were unfilled.  Can be transparent, opaque or tinted.  Filled show increased wear and abrasion resistance than unfilled. Third generation - Visible light cured of 480-490 nm wavelength.  Fourth generation - With addition of fluoride for added benefit. Soben Peter 5th edition Page no. 440
Dental
null
Fluoride pit and fissure sealants belong to which generation?
I
II
III
IV
599296cf-99e1-4a99-8322-cc24fef094a7
28週の妊娠中に間接クームステスト(ICT)が陰性のRh陰性の母親に抗Dが投与されました。次のうち理想的なものはどれですか?
赤ちゃんの血液型に応じて、出産後72時間以内にもう一度抗Dを投与します。
赤ちゃんの血液型に関係なく、出産後72時間以内にもう一度抗Dを投与します。
彼女はICT陰性なので追加投与の必要はありません。
上記のすべて
0
multi
Answer- A. Give another dose of Anti-D 72 hours postpaum depending on the baby blood groupACOG (2010) recommends anti-D immune globulin to be given prophylactically to all Rh D-negative, unsensitized women at approximately 28 weeks, and a second dose given after delivery if the infant is Rh D-positive. Before the 28-week dose of anti-D immune globulin, repeat antibocly screening is recommended to identify individuals who have become alloimmunized. Following delivery, anti-D immune globulin should be given within 72 hours.
Gynaecology & Obstetrics
null
A Rh-negative mother, who has Indirect Coombs Test (ICT), negative was given Anti-D during 28 weeks of pregnancy. Which of the following is the ideal one?
Give another dose of Anti-D 72 hours postpaum depending on the baby blood group
Give another dose of Anti-D 72 hours postpaum irrespective of baby blood group
No need of additional dose since she is ICT negative
All of the above
73818dbb-2bd3-4c46-a06a-b18b6ddb5450
WHOの根尖病変分類によると、口腔への洞はどのカテゴリーに入りますか?
4.6
4.6
4.61
4.62
3
single
null
Dental
null
According to WHO classification of periapical pathology, sinus to oral cavity comes under:
4.6
4.6
4.61
4.62
a215ecb7-fbfe-45c0-9b53-20b5188c2a87
リーマーとファイルの物理的特徴の違いは:
リーマーの断面は四角形で、ファイルの断面は三角形です。
ファイルの刃のフルートの数はリーマーよりも多いです。
リーマーは刃に多くのフルートがあります。
ファイルには、二重らせん設計でフルートを作るための2つの表面溝があります。
1
single
null
Dental
null
Difference between physical characteristic of reamers and files is:
The cross-section of reamers in square and files are triangular in cross-section
The number of flutes on the blade are more in files than in reamers
The reamers have more flutes in the blade
Files have two superficial grooves to produce flutes in a double helix design
762c8e46-a58b-4a23-b03d-f5d2055a3fac
6年間根が露出している歯に対して行われた側方滑走弁はどのような結果を示しますか?
セメント質に付着した歯根膜繊維
象牙質に付着した歯根膜繊維
以前露出していた根面に隣接する上皮
残存する繊維への適応
2
single
null
Dental
null
A lateral sliding flap done on a tooth with roots denuded for 6 years will show
PDL fibres attached to cementum
PDL fibres attached to dentin
Epithelium adjacent to previously denuded root surface
Co adaptation to the remaining fibres
9a3940ff-8c7a-492c-86d4-259c47cef675
次のうちどれが筋肉分割切開ですか?
コッヘル切開
ラザフォード・モリソン切開
Pfannenstiel切開
ランツ切開
3
single
Ans: D. Lanz incisionLanz incision:An oblique (transverse skin crease), muscle splitting incision used for an appendectomy.A modification of McBurney's (Grid Iron) incision.Advantages:Considered cosmetically better.Exposure is better.The extension is easier.Measurements:Incision, appropriate in length to size & obesity of patient - Approximately 2 cm below umbilicus centered on the midclavicular-mid inguinal line.It can be extended medially - With retraction or suitable division of rectus abdominis muscle.
Surgery
null
Which one of the following is a muscle splitting incision?
Kocher's incision
Rutherford-Morrison incision
Pfannenstiel incision
Lanz incision
c41e6817-ab7a-4208-aa4b-d89da0668ac9
患者の血清化学分析では、pCO2=30mm Hg、pO2=105mm Hg、pH=7.46が示されています。このプロファイルは何を示していますか?
代謝性アルカローシス
代謝性アシドーシス
呼吸性アルカローシス
呼吸性アシドーシス
2
single
null
Medicine
null
Serum chemistry analysis in a patient reveals pCo2=30mm Hg, pO2=105mm Hg, pH=7.46. This profile indicates
Metabolic alkalosis
Metabolic acidosis
Respiratory alkalosis
Respiratory acidosis
08261677-c2d9-467e-9b36-2860dd82c98c
IPC第304A条に基づく医療過誤の立証された場合の最高懲役刑はどれくらいですか?
1年
2年
3年
5年
1
single
Answer: b. 2 years (Ref Reddy 33/e p35, 29/e p260,Under section 304A of IPC, for a proved case of medical negligence, the maximum punishment of imprisonment is up to 2 years.
Forensic Medicine
null
Under section 304A of IPC, for a proved case of medical negligence, The maximum punishment of imprisonment is up to:
1 year
2 years
3 years
5 years
0f86c441-70a5-466d-b59f-1512fe88cbfd
母乳で育てられた子供が高ナトリウム血症(血清ナトリウム > 170mEq/L)を呈しています。尿中ナトリウムは70mEq/Lです。次のうち最も考えられる原因はどれですか?
尿崩症
急性壊死
重度の脱水症状
ナトリウムの過剰摂取
3
single
The child is having hypernatremia. Serum sodium >170 rnEq/L (Normal level is 135-145 mEq/L). Urine sodium is also very high, >70mEq/L (Normal urine sodium level in <20 mEq/L) This combination can be seen with excessive intake of sodium. With excessive intake of sodium there will be increase in serum sodium and excessive excretion of sodium in urine (Kidney tries to compensate for increase in serum sodium by excreting large amount of sodium). Diabetes Insipidus      ->    Serum sodium conc. will be high but urine sodium conc. will be very low (Lack of ADH leads to defect in concentration of urine). Acute necrosis            ->    Urine sodium conc. will be high but serum sodium conc. will be low.  Severe dehydration    ->   Urine sodium concentration will be low.
Pediatrics
null
A breast fed child presents with hypernatremia (Serum sodium > 170m Eq/L). His urine sodium is 70 mEq/L. Which of the following is the most likely cause –
Diabetes insipidus
Acute necrosis
Severe dehydration
Excessive intake of sodium
a2106819-7406-4698-8f7d-b166a05fe17e
P3L3は性交後出血とパップテスト陽性で外来に来院し、内診で子宮頸部が肥大し触診で出血する診断です。
子宮頸がん
筋腫
子宮頸管炎
子宮頸部ポリープ
0
single
Ans. A. CA cervixSYMPTOMS:Arises from: Squamo-columnar junctionEarliest symptom: Post-coital bleedingAs the cancer progresses, symptoms may include:Unusual vaginal dischargeVaginal bleeding between periodsBleeding after menopausePyometraBleeding or pain during sexMC site: EctocervixLymph nodes affected: Obturator, hypogastric and external iliacTime taken for conversion of CIN to invasive Ca: 10 yearsMC type: Squamous cell Ca100% cure rates are seen in: CISUremia: altered sensorium and is having hiccupsMC cause of death: Renal failureCa cervix can be prevented by screeningBoth positive Pap smear and test is suggestive of CA cervix
Gynaecology & Obstetrics
null
P3L3 came to opd with postcoital bleeding and pap positive p/v cervix hyperophied bleed on touch diagnosis -
CA cervix
Fibroid
Cervicitis
Cervical polyp
5e39f6db-6d90-49fa-a2a6-f9e0c9d1b821
デリーで爆発が起こり、その後2人が死亡しました。彼らの負傷について次のうち正しくないものはどれですか。
負傷は火傷と空気爆発によるものでした。
爆発の力は急速に減少する。
爆発の力は方向性がある。
打撲、裂傷、骨折は主な爆発傷害の三徴候です。
3
multi
Ans: D. Bruise, laceration, fractures are the triad of main explosive injuries seenMarshall's triad is diagnostic of explosive injury.Marshall's triad -Bruises, abrasions & puncture lacerations.Does not include fracture.
Forensic Medicine
null
A bomb blast took place in Delhi following which 2 persons died. All of the following are true about their injuries except:
Injuries occurred due to burns air blast
Force of explosion decreases rapidly
Force of explosion is directional
Bruise, laceration, fractures are triad of main explosive injuries seen
e0d991de-46ba-4a28-9f2d-788c2e1f9af5
グリーン・バーミリオン指数は何を測定しますか
歯周病
口腔衛生
骨のレベル
歯肉の健康
1
single
null
Dental
null
Green Vermillion index measures
Periodontal disease
Oral hygiene
Bone level
Gingival health
ac97880a-0862-45cf-bed5-a2000a93343c
ステージIの喉頭癌の治療法は何ですか?
根治手術
化学療法
放射線療法
手術とその後の放射線療法
2
single
Friends remember 2 very important concepts regarding laryngeal Ca: If the site of larynx caner viz supra glottis, glottis or subglottis is not mentioned, the cancer should be considered glottic (since it is the M/C variety) Generally stage I, II, III, IV means stage T1 , T2 , T3 , T4 respectively. According to Dhingra Radiotherapy is the treatment of choice for all stage I cancers of larynx, which neither impair mobility nor invade cartilage or cervical nodes. The greatest advantage of radiotherapy over surgery in Ca larynx glottic cancer is - preservation of voice.
ENT
null
The treatment of choice for stage I cancer larynx is-
Radical surgery
Chemotherapy
Radiotherapy
Surgery followed by radiotherapy
1f536213-3abd-44b5-9011-773e21fe138f
運動中にATPを最も迅速に合成する方法は何ですか?
グリコーゲン分解
解糖系
TCAサイクル
クレアチンリン酸
3
single
Ans. d. Creatine phosphate.The high group transfer potential of ATP enables it to act as a donor of high-energy phosphate compounds. There are three major sources of high phosphate compounds taking pa in energy conservation i.e. oxidative phosphorylation, glycolysis, and citric acid cycle.Phosphagens act as storage forms of group transfer potential and include creatine phosphate, which occurs in veebrate skeletal muscle, hea, spermatozoa, and brain, and arginine phosphate, which occurs in the inveebrate muscle.
Biochemistry
null
During exercise, the most rapid way to synthesize ATP is:
Glycogenolysis
Glycolysis
TCA cycle
Creatine phosphate
ace77d98-571a-4ba0-b073-881b622dcffa
眼窩の下壁を構成する骨のうち、次のうちどれが該当しないか:
篩骨(しこつ)
上顎骨
口蓋骨
頬骨
0
multi
Answer- A (Ethmoid)Kanski 5/e p558'The inferior wall of orbit consists of three bones: zygomatic, maxillary, and palatinea'.Boundaries of the OrbitRoofLesser wing of the sphenoidOrbital plate of the plateLateral wallGreater wing of the sphenoidZygomaticInferior wallZygomaticMaxillaryPalatineMedial wallFrontal process of the maxillaLacrimalEthmoidBoby of sphenoid
Anatomy
null
All of the following bones are the pas of inferior wall of orbit except:
Ethmoid
Maxillary
Palatine
ZygomaticWhile
76ba3417-012e-4bf8-840c-13bb7bc60dcc
生後30日以内に生える歯
新生児歯
先天歯
早期歯
なし
0
multi
null
Dental
null
Teeth that erupt in 30 days of birth
Neonatal teeth
Natal teeth
Premature teeth
None
e2784a8a-04af-4ced-8bf8-e6c496245df2
分娩室にいる女性にオピオイド鎮痛薬が投与されました。緊急時に備えてどの薬を準備すべきですか?
リドカイン
ナロキソン
ジフェンヒドラミン
フェンタニル
1
single
Naloxone is an opioid anatagonist given intravenously. It blocks mu, kappa and delta receptors. It is the DOC for opioid toxicity. Lignocaine is a local anaesthetic. Diphenhydramine is a first generation antihistaminic. Fentanyl is a synthetic opioid.
Pharmacology
AIIMS 2017
A female in labor ward was administered opioid analgesic. Which of the following drugs should be kept ready for emergency?
Lignocaine
Naloxone
Diphenhydramine
Fentanyl
d1bdce43-2f6d-47ee-9957-2bff4b27d2ce
精子形成の順序: 精原細胞 精母細胞 精子細胞 精子
2314
3214
3124
1234
3
single
null
Gynaecology & Obstetrics
AIIMS 2019
Sequential order of sperm formation: Spermatogonia Spermatocyte Spermatids Spermatozoa
2314
3214
3124
1234
0489f20c-a0ce-4251-9eec-e8d5e691a49e
メトプロロールを服用している高血圧の患者にベラパミルが投与されました。これはどのような結果をもたらしますか?
心房細動
房室ブロックを伴う徐脈
トルサード・ド・ポアンツ
頻脈
1
single
Metoprolol - |HR Verapamil - A-V nodal delay, |HR So, Bradycardia with AV Block - Torsade's De points: Class IA / IC / III: anti antiarrhythmic
Medicine
AIIMS 2018
A patient of hypeension on Metoprolol, Verapamil was given. This is will result in?
Atrial fibrillation
Bradycardia with AV Block
Torsades De pointes
Tachycardia
bf338178-cb15-4239-bf94-f6cfcb38d61f
糖尿病の母親から生まれた体重3.8kgの乳児が出生後16時間で痙攣を起こしました。原因は何ですか?
低血糖
低カルシウム血症
出生窒息
脳室内出血
0
single
Electrolyte disturbances, including hypoglycemia and hypocalcemia, are commonly seen in association with infants of diabetic mother and may result in early-onset seizures. Sorry friends, I could not find any reference which has directly mentioned that hypoglycemia is a more common cause of seizure than hypocalcemia in infants of diabetic mother. I was just able to find following two statements : - "Infants of diabetic mother are most at risk for hypoglycemia which can result in seizure". "Infant of diabetic mothers with seizures, that does not respond to glucose should have their serum calcium measured" From these two statements, it seems to me that hypoglycemia is a more common cause of seizures in infants of diabetic mother.
Pediatrics
null
Infant of diabetic mother with weight 3.8 Kg presented with seizures after 16 hours of birth.What is the cause –
Hypoglycemia
Hypocalcemia
Birth asphyxia
Intraventricular hemorrhage
24a53b0f-d1b7-4ef8-8b9c-1d3b857aa413
最も小さい根を持つ歯
下顎中切歯
下顎側切歯
上顎側切歯
上顎第1小臼歯
0
multi
null
Dental
null
Tooth with smallest root
Mandibular central incisor
Mandibular lateral incisor
Maxillary lateral incisor
Maxillary 1st premolar
a9210029-3bfe-4b2f-8e44-894e87e368d0
ホルモンXの受容体の局在が核内にあることが判明しました。Xは何である可能性が高いですか?
アドレナリン
インスリン
チロキシン
FSH
2
single
Ans: C. ThyroxineRef Ganong 25/e p300, 24Ie p300; Harper 30Ie p501).Thyroxine is a lipophilic hormone that acts on nuclear receptor.Steroids and thyroid hormones are distinguished by their predominantly intracellular sites of action, since they can diffuse freely through the cell membrane.They bind to a family of largely cytoplasmic proteins known as nuclear receptors.Upon ligand binding, the receptor-ligand complex translocates to the nucleus where it either homodimerizes, or associates with a distinct liganded nuclear receptor to form a heterodimer.In either case, the dieter binds to DNA to either increase or decrease gene transcription in the target tissue.
Physiology
null
Localization of the receptor of a hormone Xis found to be in the nucleus. What is likely to be X?
Adrenaline
Insulin
Thyroxine
FSH
3630ec53-489c-4040-9003-c9778939649e
ゴルジ体の機能は何ですか?
タンパク質と脂質の合成
タンパク質合成
糖タンパク質の仕分け
上記のいずれでもありません。
2
multi
null
Biochemistry
null
Golgi bodies function as:
Protein lipid synthesis
Protein synthesis
Sorting of glycoproteins
None of the above
4c6b43ff-d302-4bb0-b9b6-873cd50cb014
次のうち、どれが体からの熱損失の生理的な方法ではありませんか?
発汗
血管拡張
姿勢
末梢血管収縮
3
single
null
Physiology
null
Which of the following is not a physiological method of heat loss from the body?
Sweating
Vasodilation
Posture
Peripheral vasoconstriction
92b73e84-c02c-43db-8ddc-a5b7954ae6ab
40歳の患者が発熱のスパイクと呼吸困難を訴えて来院しました。経食道エコーで心臓に疣贅が見つかりました。培養でバークホルデリア・セパシアが陽性でした。バークホルデリア・セパシア肺炎の第一選択薬は何ですか?
アミノグリコシドとコリスチン
カルバペネムと第3世代セフェム系抗生物質
タイゲサイクリンとセフィピム
コトリモキサゾールと第3世代セフェム系抗生物質
3
single
Answer- D. Cotrimoxazole with 3rd generation cephalosporinsDrug of choice for B. cepacia is TMP-SMX and alternative agents are ceftazidime, chloramphenicolB. cepacia is the cause of a rapidly fatal syndrome of respiratory distress & septicemia ('cepacia syndrome')in cystic fibrosis Patients.Predisposing factors: cystic fibrosis & chronic granulomatous diseaseaB. cepacia inhabits moist environments and is found in rhizosphere.possesses multiple virulence factors & colonizing factors capable of binding to lung mucus (predilection of B.cepacia for the lungs in cystic fibrosis).Treatment:DOC for B. cepacia: TMP-SMXAlternative agents: Meropenem & doxycycline
Medicine
null
A 40 years old patient came with complaints of spikes of fever and difficulty in breathing. Transesophageal ECHO found out the vegetations in the hea. The culture was positive for Burkholderia cepacia. Drug of choice for Burkholderia cepacia pneumonia is:
Aminoglycoside and colistin
Carbapenems with 3rd generation cephalosporins
Tigecycline and cefipime
Cotrimoxazole with 3rd generation cephalosporins
fa33d084-57f8-470e-b0d9-9402f6518c04
仕上げ用ダイヤモンドバーのサイズ範囲はどのくらいですか?
38-44ミクロンです。
20-30ミクロンです。
10〜38ミクロンです。
上記のすべて。
2
multi
null
Dental
null
Size of finishing diamond bur ranges from:
38-44micron.
20-30micron.
10-38 micron.
All of the above.
ccca9015-2ce5-40cf-bed4-187f9428d984
55歳の患者が背中の痛みを訴えて外来に来院しました。診察では、四肢が曲がっており、皮膚が温かく厚くなっているように見えました。患者は数日間にわたって聴力の低下も訴えています。生化学分析では血清ALPが上昇していました。取得したX線には以下の特徴が示されました。最も考えられる診断は何ですか?
骨粗鬆症
骨硬化症
パジェット病
腎性骨異栄養症
2
single
Given scenario suggests diagnosis of Paget's disease. Image shows- a) Ivory veebra, b) Picture frame veebra Osteoporosis- Cod fish veebra Osteopetrosis- bone within a bone appearance Renal osteodystrophy- Rugger jersey spine
Orthopaedics
AIIMS 2019
A 55 yr old patient presented to the opd with complaint of pain in back. On examination his limbs seemed to be bent with overlying warm and thick skin. Patient also complain of decreased hearing over a few days. On biochemical analysis his serum ALP was raised. X-ray obtained showed the following features. Most probable diagnosis?
Osteoporosis
Osteopetrosis
Pagets disease
Renal osteodystrophy
0778d314-486a-4af0-b2bd-cab83e7e2166
10歳の女の子が発熱、けいれん、首の硬直を訴えて来院しました。髄液検査の結果は、タンパク質150 mg、糖40 mg、塩化物2500 mg、リンパ節腫脹が見られました。
ウイルス性髄膜炎
化膿性髄膜炎
クリプトコッカス髄膜炎
結核性髄膜炎
3
single
Typical signs of meningitis (Fever, convulsion and neck rigidity) with increased CSF protein and decreased sugar level and decreased chloride level associated with lymphadenopathy suggest the diagnosis of tubercular meningitis.
Pediatrics
null
A 10 year old girl presented with fever convulsions, neck rigidity. CSF findings are protein 150 mg, sugar 40 mg, chloride 2500 mg with lymphadenopathy –
Viral meningitis
Pyogenic meningitis
Cryptococcal meningitis
Tuberculous meningitis
ee3171ee-b65b-477b-9a73-ea8316b648aa
全身性若年性関節リウマチの特徴として次のうちどれが該当しないか –
ぶどう膜炎
発疹
発熱
肝脾腫大
0
multi
The eye manifestation are seen in Pauciarticular and Polyarticular JRA but not in systemic JRA. Juvenile Rheumatoid Arthritis can be divided in 3 major clinical types
Pediatrics
null
All of the following are features of systemic Juvenile Rheumatoid Arthritis except –
Uveitis
Rash
Fever
Hepatosplenomegaly
77f42ec8-d712-43b7-8160-dd99cad04643
10歳の子供が永久上顎中切歯の侵入をしています。治療の選択肢は
歯を元の位置に戻し、固定します。
歯が自然に萌出するのを待つ(自然萌出)
矯正治療を行います。
何もしない
1
multi
null
Dental
null
A 10 years old child has intrusion of permanent maxillary central incisor. The choice of treatment is
Put tooth in its place and splint it
Allow tooth to erupt on its own (spontaneous eruption)
Treat it orthodontically
Do nothing
87fab9d2-9419-49c1-93bf-59d0a311e8de
70歳の高血圧患者で、ステージ5の慢性腎臓病を患っている方が最近2型糖尿病と診断されました。彼は注射インスリンを使用したくありません。腎臓の用量調整が不要な経口血糖降下薬の中で、この患者に推奨されるものはどれですか?
リナグリプチン
レパグリニド
ビルダグリプチン
グリメピリド
0
single
Answer- A. Linagliptinlinagliptin has the ability to be safely dosed in chronic kidney disease patients. Chronic kidney disease is a major complication in type 2 diabetesLinagliptin .No dose required linagliptin for patients with renal impairment
Pharmacology
null
A 70 years old hypeensive patient with stage 5 chronic kidney disease was diagnosed recently with Type 2 diabetes mellitus. He doesn't want to take injectable insulin. Which of the following oral hypoglycemic agents will be preferred in this patient, which won't require any renal dose modification?
Linagliptin
Repaglinide
Vildagliptin
Glimepiride
18c1a5f9-d998-414e-bb9c-991191c10710
糖尿病の既往歴が1年あり、他に合併症のない患者は眼科検査を受けるべきですか?
できるだけ早く
5年後
10年後
視覚症状が現れた後にのみ。
0
single
Answer- A i.e. As early as feasibleAll diabetic (IDDM & NIDDM both) aged over 12 years and/or entering pubey should be screened (visual activity measurement and fundus examination by ophthalmoscopy)For retinopathy. and those with risk for visual loss referred to an ophthalmologist.Type I DM (IDDM) require ophthalmoscopic examination within 3 years of diagnosis and annual review. (If lt is diagnosed before the age of pubey).Type II DM (NIDDM) require ophthalmoscopic examination at the time of diagnosis (because it is usually diagnosed after the age of 12 years) and annual review.
Ophthalmology
null
A patient with a history of diabetes for one year with no other complications should have an ophthalmic examination?
As early as feasible
After 5 years
After 10 years
Only after visual symptoms level
8e64201e-6d6b-4187-98df-bb12e0945c78
診断は何ですか?
ハーラー症候群
ベックウィズ・ウィードマン症候群
甲状腺機能低下症
プロテウス症候群
0
single
Ans: A. Hurler's syndrome(Ref Nelson 20/e p739)Likely diagnosis = Hurler's syndrome.Hurler's syndrome:Type 1 mucopolysacharidoses.AR disorder.Characterized by alpha L-iduronidase deficiency resulting in accumulation of dermatan > heparin-sulfate.Clinical features:Presents with Goesque gargoyle facies:Coarse and heavy face.Enlarged head - Due to hydrocephalus caused by meningeal deposits.Low forehead & ears.Eyes wide set.Wide nosePoorly formed & widespread teeth.Open mouth, enlarged tongue & eveed lips.Hepatosplenomegaly.Sho neck.Thoracolumbur kyphosis.Gibbus deformity with motor delays.Flexion contracture of joints.Sho stature.Genu valgum.Fiat feet.Broad-sho hand, radially curved little finger.Carpal tunnel syndrome in children.
Pediatrics
null
A male child with coarse facial features, macroglossia, thick lips presents with copious mucous discharge from nose at 10 months of age. The child was absolutely normal at bih. On examination he was found to have enlarged Liver and Spleen. Diagnosis is:
Hurler's syndrome
Beckwith-Weidman syndrome
Hypothyroidism
Proteus syndrome
287ee601-bba2-4926-a230-388f13cfa28d
以下のうちどれが血友病患者の管理に使用されますか?
トラネキサム酸
酢酸
アスコルビン酸
パルミトン酸
0
single
null
Surgery
null
Which of the following is used in the management of haemophillic patient?
Tranxemic acid
Acetic acid
Ascorbic acid
Palmitonic acid
4bed11d9-70fd-4592-941c-6ba056318752
アルギン酸塩粉末にMgoを加えることでどの特性が変更されますか?
表面特性を向上させます。
保存期間を延ばします。
せん断強度と引裂強度を増加させます。
強度を向上させるため。
0
single
MgO added in alginate powder leads to improve its surface character mainly as well as it increased tensile strength, hardness of model, elastic modulus & Improved thermal stability.
Dental
null
Mgo added to alginate power to modify which property:
Increases surface character.
Increases shelf life.
Increases shear and tear strength.
Improve strength.
bf0eabec-95a0-46e1-a9b7-dae6c29dadde
正期産児の窒息性損傷の特徴として当てはまらないものはどれですか?
けいれん
差異的低緊張(下肢 > 上肢)
意識障害
口腔分泌物の除去が困難
1
multi
Effects ofAsphaxia : Central nervous system-                                                            Cardiovascular Hypoxic ischemic encephalopathy                                        o Myocardial ischemia Infarction                                                                                    o Poor contractility Intracranial hemorrhage                                                           o Tricuspid insufficiency Seizures                                                                                        o Hypotension Cerebral edema                                                                    o Pulmonary Hypotonia                                                                                   o Pulmonary hypertension Hypertonia                                                                                  o Pulmonary hemorrhage                                                                                              o Respiratory distress syndrome   Renal                            —> Acute tubular or cortical necrosis Adrenal                        —> Adrenal hemorrhage Metabolic                    --> SIADH, Hyponatremia, Hypoglycemia, Hypocalcemia, Myoglobinuria Integument                  -+ Subcutaneous fat necrosis Hematology                -p DIC Gastrointestinal          —> Perforation, Ulceration with hemorrhage, Necrosis During asphyxia the infant may remain hypotonic or change from hypotonia to extreme hypertonia or their tone may appear normal. These changes are seen simultaneously and the change in muscle tone is also of the same degree in both the limbs.
Pediatrics
null
Asphyxial injury in a term baby is characterized by all except –
Seizures
Differential hypotonia (lower limbs > upper limbs)
Altered sensorium
Difficulty in clearing oral secretions
e45de5c9-41f3-4aed-a77a-9a1cc3ee63db
母体死亡率は次のように表されます:
1万人あたりの母体死亡数
10万人あたりの母体死亡数
100万件の出産あたりの母体死亡数
10万出生あたりの母体死亡数
1
single
null
Gynaecology & Obstetrics
AIIMS 2018
Maternal moality ratio expressed in:-
Maternal death per 10,000 lives
Maternal death per 100,000 lives
Maternal death per 1,000,000 lives
Maternal death per 100 lives
cf9116f0-d344-4b8d-b010-050ac77a8dd1
34週で早産の赤ちゃんが生まれました。赤ちゃんの体に水疱性病変がありました。X線では骨膜炎が示されています。次の検査は何ですか?
母親と赤ちゃんのVDRL検査
HIVのELISA検査
結核のPCR検査。
母親の肝炎表面抗原検査
0
single
null
Gynaecology & Obstetrics
null
Premature baby of 34 weeks was delivered. Baby had bullous lesion on the body. X ray shows periosistis what is the next investigation:
VDRL for mother and baby
ELISA for HIV
PCR for T.B.
Hepatitis surface antigen for mother
5fa2e23f-c19c-4828-b240-59b7a0a84834
新生児を保温器に入れるための分娩室の理想的な温度は何度ですか?
22〜26度C
28〜30度C
30〜35度C
37度C
0
single
Ans: A. 22-26degC(Ref Ghai 8/e p133).Nursery temperature:Ideal temperature in delivery room for neonates in warmer state - 22-26degC (72-78"F).Should be free from drill of air.Ventilation system for each delivery & resuscitation room designed to control ambient temperature between 72-78 degrees Fahrenheit (22-26 degrees Centigrade) during delivery, resuscitation & stabilization of newborn.
Pediatrics
null
What should be the ideal temperature in delivery room for the neonates to be kept in warmer?
22-26degC
28-30degC
30-35degC
37degC
bdc34663-b39a-47bb-b034-7f804e437c09
若い男性患者が数日間5mgのハロペリドールを服用しており、最近の4日間は内的な落ち着きのなさと動きたい衝動を感じています。診断は?
アカシジア
遅発性ジスキネジア
ラビット症候群
急性ジストニア
0
single
Antipsychotic drugs Extrapyramidal symptoms- dur to D2 blockade in limbic system Extrapyramidal symptoms Clinical features Special DOC Acute dystonia Oculogyric crisis ocular muscles spasm and opisthotonos Toicollis Protrusion of tongue leading to laryngospasm grimacing Earliest to develop (days) Anticholinergic drugs Acute akathisia Constant purposeless involuntary movement from one place to another Most common EPS Days to week Propranolol Tardive dyskinesia chewing and sucking movements grimacing choreoathetoid movements-akathisia Seen after long(years) use of anti-psychotic Tetrabenazine Malignant neuroleptic syndrome Fluctuating level of consciousness hypehermia -muscles rigidity increase level of CPK Increase level of liver enzyme confusion - Diaphoresis Most common cause of death in this syndrome is acute renal failure Most serious side effect dantrolene DRUG induced parkinsonism Few weeks anticholinergics
Psychiatry
AIIMS 2017
A young male patient is on 5 mg haloperidol for many days, recently for last 4 days of duration he has inner restlessness and urges to move. Diagnosis is?
Akathisia
Tardive dyskinesia
Rabbit syndrome
Acute Dystonia
c36f9d0a-bcf4-44c2-93ef-0f83d3387664
アポタンパク質の機能は何ですか
リポタンパク質の構造成分
酵素補因子
酵素阻害剤
上記のすべて
3
multi
Apolipoproteins carry out several roles: (1) they can form part of the structure of the lipoprotein, for example, apo B; (2) they are enzyme cofactors, for example, C-II for lipoprotein lipase,  A-I  for  lecithin:cholesterol  acyltransferase,  or  enzyme inhibitors, for example, apo A-II and apo C-III for lipoprotein lipase, apo C-I for cholesteryl ester transfer protein; and (3) they Apolipoproteins carry out several roles: (1) they can form part of the structure of the lipoprotein, for example, apo B; (2) they are enzyme cofactors, for example, C-II for lipoprotein lipase,  A-I  for  lecithin:cholesterol
Biochemistry
null
Functions of apoproteins are/is
Structural component of lipoprotein
Enzyme cofactors
Enzyme inhibitors
All of the above
94cfe1dc-7810-4c50-af95-87a3c560f6bb
10日間の発熱を訴える静脈注射薬物乱用者が来院。胸部X線検査で両側下葉の浸潤と壊死、右側の膿気胸が認められる。考えられる診断は:
緑色連鎖球菌による僧帽弁心内膜炎
黄色ブドウ球菌による三尖弁心内膜炎
結核
ニューモシスチス・イロベチ感染症
1
single
Infective endocarditis typically occurs at sites of pre-existing endocardial damage, but infection with particularly virulent or aggressive organisms such as Staphylococcus aureus can cause endocarditis in a previously normal heart. Staphylococcal endocarditis of the tricuspid valve is a common complication of intravenous drug use. Many acquired and congenital cardiac lesions are vulnerable, particularly areas of endocardial damage caused by a high-pressure jet of blood, such as ventricular septal defect, mitral regurgitation and aortic regurgitation, many of which are haemodynamically insignificant. In contrast, the risk of endocarditis at the site of haemodynamically important low-pressure lesions, such as a large atrial septal defect, is minimal. Reference: : Davidson 23rd ed page no 527
Medicine
null
An I.V. drug abuser presents with fever for 10 days. CXR shows B/L lower lobe consolidation with necrosis and right sided pyopneumothorax. Probable diagnosis is:
MV endocarditis due to viridans Streptococci
TV endocarditis due to Staph. aureus
Tuberculosis
Pneumocystis jirovecii infection
5eb813a6-a84e-4b34-ae56-80e38f5a44b5
抜歯中に歯科用椅子に座っている患者が意識を失いました。患者は呼吸していますが反応がありません。最初の対応は何ですか?
椅子を倒して助けを呼び、酸素を供給します。
血圧と脈拍を確認し、気管挿管を行います。
直ちに心肺蘇生法(CPR)を開始します。
心電図
0
multi
null
Surgery
null
Patient on dental chair during extraction becomes unconscious; patient is breathing but not responsive. Your first step will be:
Recline chair and shout for help and give oxygen
Check BP and pulse and intubate
Start CPR immediately
ECG
15cebe53-6289-419d-af57-d6f5c6177147
重度の子癇前症を診断するための蛋白尿のレベルはどれくらいですか?
20 mg
200 mg
300 mg
3000 mg
2
single
Ans: C. 300 mg(Ref: Hypeension in pregnancy (ACOG laskforce on hypeension in pregnancy)-Obstetrics and gynaecology, Vol-122, No.5, November 2013; William's 24/e p181; Danfoh 10/e p264)Diagnostic criteria for pre-eclampsia:Proteinuria - 2300 mg per 24 hour urine collection.Removed from essential criterion for pre-eclampsia diagnosis by American College of Obstetricians and Gynecologists in 2013.In absence of diagnostic requirement of 5 gm as massive proteinaria for severe eclampsia - General definition of proteinuria (>300 mg) sufficient.
Gynaecology & Obstetrics
null
What is the level of proteinuria to diagnose severe preeclampsia?
20 mg
200 mg
300 mg
3000 mg
6a8fff5e-74af-48e4-8bc8-590820d078e7
警察が反応のない患者をあなたのところに連れてきました。最初に何をしますか?
すぐに胸骨圧迫を開始します。
頸動脈の脈を確認する
反応を確認し、助けを呼びます。
レスキュー呼吸を開始します。
1
multi
Ans: B. Check carotid pulse(Ref BLS/ACLS Guidelines: hups://www.resus.org.uk/resuscitation guidelines /adult-advanced-life-suppo; Harrison 19/e p1768; Braunwald's 10/e p844-845)According to Adult Basic Life Suppo (BLS) algorithm in an unresponsive patient, next step is to check carotid pulse.
Surgery
null
The police has brought an unresponsive patient to you. What is the first thing you will do?
Sta chest compressions immediately
Check carotid pulse
Check for response and call help
Sta rescue breaths
e039fc9c-d96d-44e0-9933-b4c4d87bed58
停留精巣の診断的腹腔鏡検査中に精巣血管が見当たらない場合、次に何をすべきですか?
さらに探索する
何もする必要はありません。
鼠径部探査
陰嚢検査
2
single
Answer- C
Surgery
null
During diagnostic laparoscopy for undescended testis, there are absent testicular vessels. What should be done next?
Explore fuher
Nothing is to be done
Inguinal exploration
Scrotal examination
17aac19b-ed5d-4038-9f3a-ec0c7478012e
アメロブラストーマは組織学的に何に似ていますか?
基底細胞癌 (BCC)
扁平上皮癌 (SCC)
骨肉腫
線維肉腫
0
multi
null
Surgery
null
Ameloblastoma histologically resembles:
BCC
SCC
Osteosarcoma
Fibrosarcoma
3f3eba1b-e5c8-4213-9fa1-c73b569b116d
アーチ周囲長は何で測定できますか?
セファログラム
真鍮線
ノギス
咬合X線写真
1
single
null
Dental
null
Arch perimeter can be measured with
Cephalogram
Brass wire
Vernier calipers
Occlusal radiograph
15b83eb8-206b-43e2-a4c4-4ffe3a833f98
光透過ウェッジは伝達しますか:
入射光の70-80%
入射光の80-85%
入射光の85-90%
入射光の90-95%
3
single
Light transmitting wedges As the name indicates, these types of wedges transmit 90 to 95 percent of incident light. They are a type of plastic wedges. Transparent in nature. Designed for use in the cervical area of class II composite resin restoration. Nisha Garg, Amit Garg. Textbook of Operative Dentistry.  Edition 3. Page:209
Dental
null
Light transmitting wedges transmit:
70-80% of incident light
80-85% of incident light
85-90% of incident light
90-95% of incident light
db180b6d-8b4e-487e-a47d-7c554c8dad2e
次のうちどれがエナメル質(石灰化組織)と化学結合を示しますか?
コンポジット
直接充填レジン
ポリカルボキシレートセメント
ピットおよびフィッシャーシーラントのBIS-GMA樹脂
2
single
When the powder and liquid are mixed, the surface of powder particles are attacked by the acid, releasing zinc, magnesium and tin ions. These ions bind to the polymer chain via the carboxyl groups. They also react with carboxyl groups of adjacent polyacid chains to form cross-linked salts. Structure of set cement the hardened cement consists of an amorphous gel matrix of zinc polyacrylate in which unreacted powder particles are dispersed. Key concept:- Zinc polycarboxylate cement was the first dental cement to exhibit chemical bonding to teeth, marking an improvement over the mechanical bonding of zinc phosphate cement. Zinc polycarboxylate cement is not used for restorative purposes because the cement is opaque. Ref: Phillips Ed 12th P: 318
Dental
null
Which of the following show chemical bond with enamel (calcified tissues)?
Composites
Direct filling resins
Polycarboxylate cements
BIS-GMA resins in pit and fissure sealants
a7e312f2-177e-4acf-9ac9-f68f6cb484ea
慢性アレルギーにおける抗体は?
IgM
IgA
IgG
IgE
3
multi
Answer- D- IgEWhen someone has allergies, their immune system makes an antibody called immunoglobulin E (IgE). These antibodies respond to allergens. The symptoms that result are an allergic reaction.IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic uicaria and atopic dermatitis.
Microbiology
null
Antibody in chronic allergy ?
IgM
IgA
IgG
IgE
6801ee69-6688-4bde-b9cf-ff15b165a59c
「パルスオキシメトリー」は何の測定に使用されますか?
流量
酸素飽和度
血液量
血中酸素飽和度
1
single
null
Dental
null
The "Pulse oximetry" used in the determination of:
Rate of flow
Oxygen saturation
Blood volume
Blood coefficient
16230bcb-8896-467c-ae66-616676d00b65
肉眼で第2近心頬側根管が見えるのは何パーセントの症例ですか
62-70%
90-95%
30%
40-55%
0
single
null
Dental
null
2nd Mesiobuccal canal can be seen from naked eyes in what percentage of cases
62-70%
90-95%
30%
40-55%
38c0c9e6-009c-4ef1-a3ae-2e3aacd715e7
黒い足はどの中毒で見られますか?
ヒ素
水銀
リン
0
single
Black foot disease is caused by arsenic poisoning since it causes thrombosis of vessels and may cause peripheral gangrene. Mnemonic Arsenic poisoning A - Anemia / Aldrich Mee's line / Arsenophagist (Tolerate upto 300mg ) R - Rain drop pigmentation / Reinsch test / Red velvety mucosa S - Sub endocardial hemorrhages / Sensory neuropathy E - Eruptions N - NAA I - Imbibition of arsenic ( Arsenic imbibed from surrounding soils after death ) / before treated iron oxide C - Cumulative poison / Cholera like symptom / Chelation for treatment
Forensic Medicine
AIIMS 2017
Black foot is seen in which poisoning?
Arsenic
Lead
Mercury
Phosphorus
dba5fe86-0faa-4037-bc20-e6b88972370d
アマルガム研磨後、最外層には歯の表面に平らに配置された結晶があります。この層は何と呼ばれますか
ベイルビー層
ベイリル層
ベイビル層
上記のいずれでもない
0
multi
null
Dental
null
After amalgam polishing, the outermost surface has crystals arranged flattened to tooth surface. This layer is known as
Beilby layer
Beillyl layer
Beibyl Layer
none of the above
d2ca31a3-800c-4bf7-b150-a3981acc7587
以下のうち筋筋膜痛機能障害症候群に関する誤った記述はどれですか?
主に若い女性に影響を与える
歯ぎしりや食いしばりなどの慢性的な口腔習慣による筋肉の疲労が原因です。
治療には咬合ガードの作成とストレスのない精神状態が含まれます。
口周囲の筋肉が低緊張になる
3
multi
null
Pathology
null
Which of the following statements is false in relation to myofacial pain dysfunction syndrome?
Mainly affects young females
Is caused by muscle fatigue due to chronic oral habits as grinding and clenching
Treatment involves construction of occlusal guard and stress free emotional condition
The perioral musculature becomes hypotonic
ff70acbd-354f-4d68-bf18-74a4c6489695
体重75 kgの患者で、pH = 6.96、pCO2 = 30 mm Hg、HCO3- = 6 mEq/Lの場合の塩基欠乏を計算してください。
300 mEq
400 mEq
500 mEq
800 mEq
2
single
Ans: C. 500 mEq(Ref Harrison 19/e p317, 12/e p368).Base deficit in question = 400 mEq.Base excess & base deficit:Refer to an excess or deficit respectively in amount of base present in blood.Total bicarbonate deficit = 0.3 x weight (kg) x base deficitBase deficit in mEq = 0.4 x weight (kg) x Total Base Deficit = (24-6) x 0.4 x 75 = 540 mEq = 500 mEq (approx.)To obtain deficit in grams, divide mEq by 12.
Medicine
null
Calculate the base deficit in a patient of weight 75 kg with a pH = 6.96, pCO2 = 30 mm Hg and HCO3- = 6 mEq/L:
300 mEq
400 mEq
500 mEq
800 mEq
09ce3345-10ca-4ade-91b7-8b1361c55c99
モルヒネは治療に使用してはいけないのは:
虚血性疼痛
胆石疝痛
がんの痛み
術後の痛み
1
single
Morphine (an opioid) is a strong analgesic. It is used in treatment of all types of pain like Crush injury, Fracture, MI, cancer pain, post-operative pain etc. However in Biliary colic (e.g. due to any stone blocking bile duct), morphine constricts sphincter of Oddi and increase the intrabiliary pressure. This increases the chances of rupture of bile duct. Therefore opioids like morphine are contra-indicated in biliary colic.
Pharmacology
AIIMS 2018
Morphine should not be used in the treatment of:
Ischemic pain
Biliary colic
Cancer pain
Post operative pain
32cb89d3-375d-4ada-873b-4ae11edd21a1
上顎第一大臼歯の何パーセントに二つの口蓋根が見られますか
1-4%
2-10%
0-1 %
二つの口蓋根は決して見られません。
0
single
null
Dental
null
Two palatal roots are found in what percentage of maxillary 1st molars
1-4%
2-10%
0-1 %
Two palatal roots are never found
9c7e163e-d22f-43d9-8c77-fb036bc0b064
2週間前に心筋梗塞を起こした60歳の患者の脂質プロファイルが行われ、HDL 32 mg/dL、LDL 126 mg/dL、TG 276 mg/dLと判明しました。この患者に推奨されるのは次のうちどれですか?
ロスバスタチン + フェノフィブラート
フェノフィブラート単独
ロスバスタチン 10 mg
アトルバスタチン 80 mg
3
single
Answer- D. Atorvastatin 80 mgWhen lipid-lowering agents are indicated, the treatment is staed with IIMG Co-A reductase inhibitors (statins). High intensity statin therapy should be staed in the patients with presence of clinical atherosclerotic cardiovascular events (MI in this patient). In high intensity statin therapy, either atorvastatin (40-80 mg/day) or rosuvastatin (20-40 mg/day) should be given.High lntensity Statin TherapyLowers LDL cholesterol by approximately 50% .Drugs used:Atorvastatin (40-80 mg)Rosuvastatin (20-40 mg)
Medicine
null
A 60 years old patient who had myocardial infarction 2 weeks back, the lipid profile is done for a patient and reveals HDL 32 mgldL, LDL 126 mg/dl, TG 276 mgl/dL. Which of the following is preferred for this patient ?
Rosuvastatin + Fenofibrate
Fenofibrate alone
Rosuvastatin 10 mg
Atorvastatin 80 mg
c6da06a8-62d4-49b1-9bce-e4584bbadc62
膀胱尿管逆流はどちらに多いですか?
新生児の女児
年上の女の子
年長の男の子
妊娠中のみ
0
single
Clinical manifestations of VUR In primary reflux the average age ofpresentation is 2-3 years. Reflux is more common in females and it is usually detected earlier in females so we can say that reflux is present from birth but it is usually detected at 2-3 years of age but in feinales the age of detection is earlier. Features are - In primary reflux the patient usually presents with symptoms of pyelonephritis or cystitis. In secondary reflux manifestation of primary diseases are usually the presenting symptoms Reflux is the most common cause of pyelonephritis. It is seen in 30-50% of patients with pyelonephritis. It is present in over 75% of patients with radiological evidence of chronic pyelonephritis Diagnosis of Vesicoureteric reflux - The most useful process for conclusive diagnosis of reflux is micturating cystourethrogram. This will demonstrate the grade of reflux as well as urethral anatomy. The other useful technique for detecting vesicoureteric reflux is radionuclide imaging. It is extremaly sensitive at detecting reflux but do not demonstrate the anatomic detail seen with voiding cystourethro gram. So they are used for follow up after micturating cystourethrogram because they offer less radiation exposure.
Pediatrics
null
Vesicoureteric reflux is more common in –
Newborn females
Older girls
Older boys
Only during pregnancy
953391a8-ee52-4e36-879f-67eaf1f68ae3
最大咀嚼力を受けるのはどの繊維ですか?
歯槽頂
斜走繊維
水平繊維
根尖部
1
single
null
Dental
null
Maximum masticatory forces taken up by which fibers:
Alveolar crest
Oblique
Horizontal
Apical
d321d320-c06f-4d18-9aa2-dae718851dfd
NiTiファイルを腐食から防ぐために、122度FのNaOClにどのくらいの時間浸漬すべきですか?
20分
45分
60分
2時間
2
single
Direct lines from book "warming of NaOCI to 122° F (50' C) leads to increase in collagen dissolution as potential to disinfecting, but it can leads to detrimental corrosion effects on NiTi instruments immersion for 1 hr".
Dental
null
For how long should NiTi files be submerged in NaOCl at 122-degree F to prevent damage to file corrosion
20 mins
45 mins
60 mins
2 hours
1f473717-d2b8-489e-969e-be0de6c30e86
コラーゲンの推定に使用されるアミノ酸は何ですか?
ヒドロキシプロリン
プロリン
リシン
グリシン
0
single
null
Biochemistry
null
The amino acid, which is used in the estimation of collagen is:
Hydroxyproline
Proline
Lysine
Glycine
743f2305-10ed-4d66-b6fa-911cacdf2622
Rh同種免疫に影響されないHbの種類はどれですか?
抗C
抗E
抗ルイス
抗D
2
single
“An antigen frequently found in routine antenatal screening is the Lewis group (Lea and Leb). The Lewis antigens do not cause erythroblastosis fetalis and differ from all of the other red cell antigens in that they are not synthesized in the red cell membrane but are absorbed into it.” Fernando Arias 2/e, p 116
Gynaecology & Obstetrics
null
Which type of Hb is not affected by Rh isoimmunisation:
Anti C
Anti E
Anti lewis
Anti D
e1eb342e-fe1e-49b1-a9d7-f8400b419aa6
エッジ・トゥ・エッジの位置での早期接触は、以下を減らすことで解消されます。
下顎切歯の切縁。
上顎の舌側窩。
両方AB
ABのいずれか
0
multi
null
Dental
null
Pre-maturity in edge to edge position is relieved by reducing:
Mandibular incisal edge.
Maxillary lingual fossa.
Both AB
Either AB
b31e3c42-29b5-4773-aec7-c8e8c7c9e444
根尖孔は根尖にあります
17〜46%の症例で
5-10%の症例
10-30%の症例
100%の症例で
0
single
null
Dental
null
Apical foramen is found at root apex in
17-46% of cases
5-10 % of cases
10-30% of cases
100% of cases
653d9209-e3ec-4f56-bb30-6e9f74c210df
麻疹の隔離期間:
前駆期の開始から発疹の7日目まで
発疹期から発疹後2日まで
前駆期の開始から発疹の3日目まで
発疹期から発疹の7日目まで
2
single
Isolation period of measles is Onset of prodromal phase until 3rd day of rash. Maximum communicability occurs from onset of prodrome through the first 3-4 days of rash.Prodromal phase-stage last for 4 days(from 10th to 14th day of infection) characterized by Fever, Koplik spots , coryza, nasal discharge, redness .Incubation period of measles is 10 daysEruptive phase- Maculopapular rash appear after 4 days of fever (14day after infection)
Microbiology
AIIMS 2018
Isolation period of measles:-
Onset of prodromal stage until 7th day of rash
Eruptive stage until 2 days of rash
Onset of prodromal phase until 3rd day of rash
Eruptive stage until 7th day of rash
5101251c-4a2d-455e-81ec-547c58511440
結核後気管支拡張症の患者の聴診で、次のうちどれを観察しますか?
遅発性吸気性ラ音
両側基底部の捻髪音
早期および後期の吸気性ラ音の両方
管状呼吸音
2
multi
Ans: C. Both early and late inspiratory crackles(Ref: Harrison 19/e p1661-1665, 18/e p2143)Post-tuberculous bronchiectasis affect one lung only & produce coarse crackles, which are usually biphasic.Bihasilar crepitations:Typical of fluid overload (due to pulmonary edema).Occur in both inspiration and expiration. Combination of coarse and fine crackles.Feature of bronchiectasis.Related to a combination of secretions and increased compliance of the walls in larger airways."Late inspiratory fine crackles - In COPD or pneumonia.Tubular breathing - In Lung consolidation.
Medicine
null
In a patient with post-tuberculosis bronchiectasis, which of the following will you observe on auscultation?
Late inspiratory crackles
Bibasilar crepts
Both early and late inspiratory crackles
Tubular breath sounds
ef300ffa-be04-4c72-b18c-8e584ad89b20
メドラー小体はどこに見られますか?
スポロトリコーシス
クロモブラストミコーシス
マイセトーマ
ヒストプラズマ症
1
single
Answer- B. ChromoblastomycosisMedlar bodies, also known as a sclerotic or muriform cell, When present in the skin or subcutaneous tissue, the cells are indicative of chromoblastomycosis.Chromoblastomycosis (CBM) is defined as a chronic cutaneous and subcutaneous fungal infection resulting from traumatic implantation of ceain dematiaceous fungi through the skin. In the infected tissue, characteristic dark-colored, thick-walled, muriform cells i.e. sclerotic cells (Medlar bodies) are seen.
Pathology
null
Medlar bodies are found in -
Sporotrichosis
Chromoblastomycosis
Mycetoma
Histoplasmosis
61146ef9-e5d8-48c4-8031-a04cbb34c97e
患者の上顎側切歯領域に腫れがあり、過去48時間にわたって腫れが熱く触知可能で、圧力をかけると反発します。治療の選択肢は何ですか?
切開と排膿
抗生物質の投与
抗生物質のみ
吸引
0
single
null
Surgery
null
There is a swelling in a patient with respect to maxillary LI region, since last 48 hours, the swelling is hot & palpable & rebounds on pressure, the treatment of choice is
Incision & drainage
Antibiotic coverage
Antibiotics of heat only
Aspiration
76eb0208-23fa-422d-aa0b-c4d5ec0fc3b5
咬合位において、上顎第2小臼歯の舌側咬頭はどこに接触しますか?
下顎第2小臼歯の遠心窩
下顎第1大臼歯の近心窩
下顎第2大臼歯の遠心辺縁隆起
下顎第1小臼歯の遠心辺縁隆起
0
single
null
Dental
null
In the intercuspal position, the lingual cusp of maxillary 2nd premolar contacts the:
Distal fossa of mandibular 2nd premolar
Mesial fossa of mandibular 1st molar
Distal marginal ridge of mandibular 2nd molar
Distal marginal ridge of mandibular 1st premolar
82089776-70c7-48e0-94ae-753e8b72949f
下顎骨の骨折で下顎の高さが8mmの場合、治療方針は:
シャンピーのプレート
ラグスクリュー
再建プレート
上記のすべて
2
multi
As reconstruction plate is load bearing plate.
Surgery
null
Fracture of mandible having mandibular height 8 mm, line of treatment:
Champy's plate
Lag screw
Reconstruction plate
All of the above
9a901f04-8eb8-4e4f-a332-14cf2a3c70a3
アンピシリンにクラブラン酸を加えるとどうなりますか?
グラム陰性菌に対する効果が増加します。
β-ラクタマーゼの阻害
デルタラクタマーゼ産生菌に対する効果が増加します。
グラム陽性菌に対する効果が増加します。
1
single
null
Pharmacology
null
Clavulanic acid added to ampicillin causes:
Increase effectivity against gram-negative organisms
Inhibition of β-lactamases
Increases the effectiveness against delta lactamase producing organism
Increase effectivity against gram-positive organisms
4067ea1a-de54-4762-a2d8-54acaaf54a18
妊娠中の肝炎感染に関する次の記述のうち、どれが正しいですか?
B型肝炎コア抗原の状態は、疾患の垂直感染が陽性であることを示す最も敏感な指標です。
輸血後の肝炎の中で最も一般的なのはB型肝炎です。
感染した母親から生まれた乳児の適切な治療には、肝炎B免疫グロブリンの投与とワクチンの接種が含まれます。
慢性活動性肝炎を発症した患者はMTPを受けるべきです。
2
multi
Persons at increased risk of hepatitis B infection include homosexuals, abusers of intravenous drugs, healthcare personnel, and people who have received blood or blood products. However, because of intensive screening of blood for type B hepatitis, hepatitis C has become the major form of hepatitis after blood transfusion. (i.e. option b. incorrect). The most sensitive indicator of positive vertical transmission of disease is HBe antigen. (i.e. option a. incorrect). The proper treatment of infants born to infected mothers include administration of hepatitis B immune globulin as well as vaccine. Chronic acute hepatitis does not necessarily warrant therapeutic abortion (i.e. option d. incorrect). Fertility is decreased, but pregnancy may proceed on a normal course as long as steroid therapy is continued. Prematurity and fetal loss are increased, but there is no increase in malformations.
Gynaecology & Obstetrics
null
Which of the following statements concerning hepatitis infection in pregnancy is true?:
Hepatitis B core antigen status is the most sensitive indicator of positive vertical transmission of disease
Hepatitis B is the most common form of hepatitis after blood transfusion
The proper treatment of infants born to infected mothers includes the administration of hepatitis B immune globulin as well as vaccine
Patients who develop chronic active hepatitis should undergo MTP
0f8e11c2-a438-4c71-86fb-e302e5852a05
両親が軟骨無形成症の場合、影響を受けない赤ちゃんが生まれる確率はどれくらいですか?
0%
25%
50%
100%
1
multi
First see general features of autosomal dominant disorders - Autosomal dominant disorders are manifested in heterozygous state. So, at least one of the parent should be affected to transmit the disease to child. Homozygous state does not exist as it is not compitable with life, i.e. homozygous fetus usually dies in utero. So, all the affected individuals will be heterozygous. If an affected person marries an unaffected one, i.e. if one of the parents is affected than every child has 50% of chance of having the disease and 50% of chance not having the disease.
Pediatrics
null
The chances of having an unaffected baby, when both parents have achondroplasia, are –
0%
25%
50%
100%
9220447e-0ac6-41b7-b22d-07d1340b3641
乳がんとリスク要因に関する症例対照研究が行われ、オッズ比が得られました。以下のうち、原因となる要因はどれですか?パラメータ症例対照OR初経年齢>12171423291.04閉経177124081.53経口避妊薬使用93511051.02喫煙932140.97家族歴5135021.10BMI>27.51654930.53授乳94225140.56多産(2)277833661.05
6
1
single
Ans. (B) 5An odds ratio (OR) is a statistic that quantifies the strength of the association between two events, A and B.Two events are independent if and only if the OR equals 1: the odds of one event are the same in either the presence or absence of the other event.If the OR is greater than 1, then A and B are associated (correlated) in the sense that, compared to the absence of B, the presence of B raises the odds of A, and symmetrically the presence of A raises the odds of B.Conversely, if the OR is less than 1, then A and B are negatively correlated, and the presence of one event reduces the odds of the other event.Most Impoantly Odds ratio does not demonstrate causality .But we can say that they are positively correlated. Since 5 Factors have odds ratio more than 1 so the answer will be B
Social & Preventive Medicine
null
Case control study was done regarding breast cancer & risk factors & odds ratio was obtained. Which of the following are causative factors ?ParameterCaseControlORAge at menarche>12171423291.04Menopause177124081.53OCP use93511051.02Smoking932140.97Family history5135021.10BMI>27.51654930.53Breastfeeding94225140.56Multiparity(2)277833661.05
6
5
3
2
8b9c73e9-4e2e-4e4b-8216-9c043a1282cf
単純無作為抽出は何に理想的ですか?
ワクチン接種を受けた人々
異質な集団
均質な集団
上記のすべて
2
multi
null
Dental
null
Simple random sampling is ideal for:
Vaccinated people
Heterogenous population
Homogenous population
All of the above
9a292f87-6a2d-4bba-bcee-f11ca9a94c73
オイルレッドO染色は何に使用されますか?
グルタルアルデヒド固定標本
アルコール固定標本
ホルマリン固定標本
凍結標本
3
single
Ans: D. Frozen specimenFor Connective Tissue and LipidsName of stainElements stainedTrichrome StainCollagenVerhoeff-Van Gieson stain (Best for Elastin)Elastic fibersLuna stainElastin & Mast cellsSilver Methenamine stainReticulinOil red '0' stain (on Fresh specimen)Sudan black (on fixed specimen)FatMallory's PTAH stainMuscle striationsMaius scarlet blue (MSB)FibrinPAS, Silver Methenamine stainBasement membraneBielschowsky (silver stain)Neurofibrillary tangles senile plaquesLuxol fast blueMyelin(Ref Netter :s* Essential Histology 2/e p479)
Pathology
null
Oil red '0' stain is used for:
Glutaraldehyde fixed specimen
Alcohol fixed specimen
Formalin fixed specimen
Frozen specimen
25ad5741-fdb7-49d7-b985-aa021e70a967
「涼しい場所に保管」と薬のラベルに書かれています。これは薬をどの温度で保管すべきかを意味しますか?
摂氏マイナス2度
摂氏0度
摂氏2〜8度
摂氏8〜15度
3
single
STORAGE TEMPRATURES: LABEL WHERE TO KEEP TEMPRATURE Keep frozen Inside freezer -20 degree celsius Keep cold Inside refrigerator; outside freezer 2-8 degree celsius Keep cool Outside refrigerator 8-15 degree Celsius(in USA); 8-25 degree Celsius (in India)
Pharmacology
AIIMS 2018
'Store in a cool place' is written on a drug label. It means drug should be stored at a temperature of:
-2 degree Celsius
0 degree Celsius
2-8 degree Celsius
8-15 degree Celsius
bcc3680a-8167-4c75-ba0c-b7c94cb440b6
交絡を除去するために行われるのは次のうちどれですか。
無作為化
無作為抽出
マッチング
盲検法
1
multi
Confounding factor - related to both the exposure and the outcome It leads to mistaken outcomes in the study, which leads to error in the study. Endemic Goitre is usually found in high altitudes, showing thereby an association between the two. However, we know that the goiter is not because of altitude but because of environmental deficiency of Iodine. Methods used to control confounding: Methods used to control confounding: METHOD UTILITY IN CONTROLLING CONFOUNDING 1. Randomization Most ideal method 2. Restriction Limiting study to people who have paicular characteristics 3. Matching Mostly useful in case control studies 4. Stratification Useful for larger studies 5. Statistical Modeling When many confounding variables exist simultaneously 6. Blinding Bias is also a type of confounding
Social & Preventive Medicine
AIIMS 2019
All of the following are done to remove Confounding except
Randomization
Random Selection
Matching
Blinding
07c14e46-ad2b-4fde-8652-bd47b36e69ab
バソプレシン拮抗薬はネフロンのどの部分に作用しますか?
近位尿細管
遠位曲尿細管
皮質集合管
髄質集合管
3
single
Answer- D (Medullary collecting duct)'The mechanism by which vasopressin exes its anti-diuretic effect is activated by V2 receptors and involves the inseion of aquaporin-2 into the apical (luminal) membranes at the principle cells of the collecting duct.'
Pharmacology
null
Vasopressin antagonist acts on which pa of the nephron?
Proximal convoluted tubule
Distal convoluted tubule
Coical collecting tubule
Medullary collecting duct
ebb422b3-9745-4b38-8192-4557d6bcf595
次のうち、後方手術により生じた口腔洞瘻の治療に使用できる手技はどれですか: (または) 上顎第3大臼歯領域の口腔洞瘻は最もよく/一般的にどのように治療されますか。
頬側粘膜骨膜弁
口蓋粘骨膜弁
ブリッジフラップ
口蓋島状弁
3
single
null
Surgery
null
Which of the following procedures can be used to treat an oro-antral fistula resulting from posterior surgery: (Or) Oro-antral fistula in maxillary 3rd molar region is best/commonly treated by
Buccal mucoperiosteal flap
Palatal mucoperiosteal flap
Bridge flap
Palatal island flap
dc248bc1-20c6-4aca-a7db-3642df59fe8a
以下のうち、内因性または外因性経路によって活性化されるのはどれですか?
ネクロプトーシス
アポトーシス
壊死
パイロトーシス
1
single
Apoptosis results from the activation of enzymes called caspases (so named because they are cysteine proteases that cleave proteins after aspaic residues). Two distinct pathways converge on caspase activation: the mitochondrial pathway (Intrinsic pathway) and the death receptor pathway( Extrinsic Pathway).
Pathology
AIIMS 2019
Which of the following is activated by intrinsic or extrinsic pathway's?
Necroptosis
Apoptosis
Necrosis
Pyroptosis
027df73a-b277-4ad7-aba2-824c58fc78e1
WHOのガイドラインによると、過剰な糖分摂取の制御について、すべての人を除いて
財政政策
チェアサイドカウンシル
マーケティング
食品表示
1
multi
null
Dental
null
According to WHO guidelines for excess sugar control by all except
Fiscal policies
Chair side council
Marketing
Food Labelling
9998be8f-9725-46f3-9891-4ec3f18812ce
バブさん、49歳の患者は、悪臭のある息と数日前に食べた食べ物の逆流を訴えています。また、嚥下障害も訴えています。考えられる診断は:
胃麻痺
アカラシア
糖尿病
咽頭憩室
3
single
null
Medicine
null
Babu, a 49-year-old patient, complains of foul breath and regurgitation of food eaten few days back. He also complains of dysphagia. The probable diagnosis is:
Gastrophoresis
Achalasia
Diabetes
Pharyngeal pouch
250445f9-5a5a-45c0-9035-f581f79f5030
多嚢胞性卵巣症候群について正しいのは次のうちどれですか?
持続的に高いLH
LH/FSH比の増加
DHEA-Sの増加
プロラクチンの増加
3
multi
In patients of PCOS: Alterations in gonadotropin releasing hromone pulsatality leads to preferential production of LH, as compared to FSH. Also estrogen has a positive feedback on LH and negative feedback on FSH which leads to increase in LH and decrease in FSH such that LH/FSH is > 2.1. Now the question arises whether this increase in LH is persistent. Most of the books do not state anything clearly except that there is an increase in the LH pulse amplitude and frequency. So I had to look up in Leon Speroff (which is the BAAP of all problems related to endocrinology and infertility in Gynae).
Gynaecology & Obstetrics
null
All are true about polycystic ovarian disease except:
Persistently elevated LH
Increased LH/FSH ratio
Increased Dheas
Increased prolactin