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abstract stringlengths 0 21.1k	author stringlengths 0 279k	content_list listlengths 1 17.2k	doi stringlengths 0 69	is_oa bool 1 class	language stringclasses 43 values	sci_category stringclasses 27 values	sha256 stringlengths 64 64	title stringlengths 0 2.36k
Solar flares are strong radiation bursts, whereas large clouds of solar material and magnetic fields that erupt at high speeds from the Sun are coronal mass ejections. Harmful radiation from a flare does not pass through the atmosphere of the Earth to physically impact humans on the ground, but can disrupt the atmosphere in the layer where GPS and communication signals travel. Flares generate results across the entire electromagnetic spectrum. They emit x-rays and ultraviolet radiation, which means extremely high temperatures during a flash. Radio waves mean that tiny fractions of particles are accelerated to high levels of energy. Most of the radiation is synchrotron radiation produced along magnetic field lines by electrons traveling along spiral paths. In this paper was monitored solar flare registered on February 25, 2015. This flare, which peaked at 00:49 am EDT from a sunspot called Active Region 1990 (AR1990), is classified as an X4.9-class flare. We have performed solar data analysis using the Python/SunPy tool. SunPy was chosen as the principle data analysis environment since it provides easy to use interfaces to the Virtual Solar Observatory (VSO). © 2020, al-Farabi Kazakh State National University. All rights reserved.	Sarsembayeva, A.\|Belisarova, F.\|Odsuren, M.\|Sarsembay, A.	[ { "bbox": "[225,129,752,149]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.26577/phst.2020.v7.i2.03	true	en	Astronomy and Space Sciences	019c9f36852e1832bdfa44f8cd7351ec9dc9171dc769a2e876a29aeb386fb95e	February 25, 2014 solar flare data analysis in SunPy
ε-Poly-L-lysine (ε-PL) is a natural amino acid polymer produced by microbial fermentation. It has been mainly used as a preservative in the food and cosmetics industries, as a drug carrier in medicines, and as a gene carrier in gene therapy. ε-PL synthase is the key enzyme responsible for the polymerization of L-lysine to form ε-PL. In this study, the ε-PL synthase gene was overexpressed in Streptomyces albulus CICC 11022 by using the kasOp∗ promoter and the ribosome binding site from the capsid protein of phage ϕC31, which resulted in a genetically engineered strain Q-PL2. The titers of ε-PL produced by Q-PL2 were 88.2% ± 8.3% higher than that produced by the wild strain in shake flask fermentation. With the synergistic effect of 2 g/L sodium citrate, the titers of ε-PL produced by Q-PL2 were 211.2% ± 17.4% higher than that produced by the wild strain. In fed-batch fermentations, 20.1 ± 1.3 g/L of ε-PL was produced by S. albulus Q-PL2 in 72 h with a productivity of 6.7 ± 0.4 g/L/day, which was 3.2 ± 0.3-fold of that produced by the wild strain. These results indicate that ε-PL synthase is one of the rate-limiting enzymes in ε-PL synthesis pathway and lays a foundation for further improving the ε-PL production ability of S. albulus by metabolic engineering.	Bo Yu\|Wenzhe Tian\|Jiayang Qin\|Lei Cheng\|Aixia Wang\|Youqiang Xu\|Xiuwen Wang	[ { "bbox": "[294,196,904,345]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3389/fbioe.2020.00288	true	en	Life Sciences	d361089a05cc8b442c64560aa8586f9e34363e21118323d558e59f0e116c947d	Enhanced ε-Poly-L-Lysine Production by the Synergistic Effect of ε-Poly-L-Lysine Synthetase Overexpression and Citrate in Streptomyces albulus
<div class="section abstract" id="abstract-1"><h2 class="">Abstract</h2><div id="sec-1" class="subsection"><p id="p-2"><strong>Background</strong> A suite of mammalian species have experienced range contractions following European settlement and post-settlement development of the North American continent. For example, while North American martens (American marten, <em>Martes americana</em>; Pacific marten, <em>M. caurina</em>) generally have a broad range across northern latitudes, local populations have experienced substantial reductions in distribution and some extant populations are small and geographically isolated. The Humboldt marten (<em>M. c. humboldtensis</em>), a subspecies of Pacific marten that occurs in coastal Oregon and northern California, was recently designated as federally threatened in part due to its reduced distribution. To inform strategic conservation actions, we assessed Humboldt marten occurrence by compiling all known records from their range.</p></div><div id="sec-2" class="subsection"><p id="p-3"><strong>Methods</strong> We compiled Humboldt marten locations since their rediscover to present (1,692 marten locations, 1996-2020). We spatially-thinned locations to 500-m to assess correlations with variables across contemporary Humboldt marten distribution (n=384). Using maximum entropy modeling (Maxent), we created distribution models with variables optimized for spatial scale; pre-selected scales were associated with marten ecology (50 to 1170 m radius). Marten locations were most correlated with abiotic factors (e.g., precipitation), which are unalterable and therefore uninformative within the context of restoration or management actions. Thus, we created variables to focus on hypothesized marten habitat relationships, including understory conditions such as predicted suitability of shrub species.</p></div><div id="sec-3" class="subsection"><p id="p-4"><strong>Results</strong> Humboldt marten locations were positively associated with increased shrub cover (salal (<em>Gautheria shallon</em>), mast producing trees), increased pine (<em>Pinus sp</em>) overstory cover and precipitation at home-range spatial scales, areas with low and high amounts of canopy cover and slope, and cooler August temperatures. Unlike other recent literature on the species, we found little evidence that Humboldt marten locations were associated with old growth structural indices, perhaps because of a potential mismatch in the association between this index and shrub cover. As with any species distribution model, there were gaps in predicted distribution where Humboldt martens have been located during more recent surveys, for instance the southeastern portion of Oregon’s coast range. Conservation efforts and our assessment of potential risks to Humboldt marten populations would benefit from additional information on range extent, population sizes, and fine-scale habitat use. Like many rare and lesser-known species, this case study provides an example of how limited information can provide differing interpretations, emphasizing the need for study-level replication in ecology.</p></div></div>	Katie Moriarty, Joel Thompson, Matthew Delheimer, Brent Barry, Mark Linnell, Taal Levi, Keith Hamm, Desiree Early, Holly Gamblin, Micaela Szykman Gunther, Jordan Ellison, Janet S. Prevéy, Jennifer Hartman, Ray Davis	[ { "bbox": "[109,88,848,141]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1101/2021.02.05.429381	true	en	Life Sciences/Earth and Atmospheric Sciences	a1c5c57b06a6cc6e6cbfad2c3f19341946cdf3dd2c8458e0fab2f5455eaa5955	Predicted distribution of a rare and understudied forest carnivore: Humboldt martens ( <i>Martes caurina humboldtensis</i> )
The paper describes the design and manufacturing process of a fiber optic microphone based on a macro cavity at the end face of an optical fiber. The study explores the step-by-step fabrication of a droplet-shaped macro cavity on the optical fiber's end surface, derived from the formation of a quasi-periodic array of micro-cavities due to the fuse effect. Immersing the end face of an optical fiber with a macro cavity in liquid leads to the formation of a closed area of gas where interfacial surfaces act as Fabry–Perot mirrors. The study demonstrates that the macro cavity can act as a standard foundational element for diverse fiber optic sensors, using the droplet-shaped end-face cavity as a primary sensor element. An evaluation of the macro cavity interferometer's sensitivity to length alterations is presented, highlighting its substantial promise for use in precise fiber optic measurements. However, potential limitations and further research directions include investigating the influence of external factors on microphone sensitivity and long-term stability. This approach not only significantly contributes to optical measurement techniques but also underscores the necessity for the continued exploration of the parameters influencing device performance.	Morozov, Oleg\|Agliullin, Timur\|Sakhabutdinov, Airat\|Kuznetsov, Artem\|Valeev, Bulat\|Qaid, Mohammed\|Ponomarev, Roman\|Nurmuhametov, Danil\|Shmyrova, Anastasia\|Konstantinov, Yuri	[ { "bbox": "[53,122,107,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/photonics11010022	true	en	Engineering and Manufacturing Science	e258239470c38b450e32bb9b3f279f695df9ac28a27c637d1acc976fdc5b9a43	Fiber-Optic Hydraulic Sensor Based on an End-Face Fabry–Perot Interferometer with an Open Cavity
	Xia, Haijuan\|Du, Jiulin	[ { "bbox": "[70,134,907,191]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1002/ctpp.201900154	true	en	Physics	b1e3df94b48620c2e9e730d9ddfc8ad31e458512abe38cab57e7df29d0fada60	Heat conductivity and Dufour effect in the weakly ionized, magnetized, and kappa‐distributed plasma
	Chiotellis, A\|Boumis, P\|Spetsieri, Z T	[ { "bbox": "[65,92,880,140]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1093/mnras/staa3573	true	en	Physics	acd8a57fe2cdd4076ceebb0241dd649152b9412781ea02b7723b640b9636a247	‘Ears’ formation in supernova remnants: overhearing an interaction history with bipolar circumstellar structures
Taurine (2-aminoethanesulfonic acid) plays an important role in various physiological functions and is abundant in the brain and skeletal muscle. Extracellular taurine is an endogenous agonist of gamma-aminobutyric acid type A and glycine receptors. Taurine actively accumulates in cells via the taurine transporter (TauT). Adult taurine-knockout (TauT-/-) mice exhibit lower body weights and exercise intolerance. To further examine the physiological role of taurine, we examined the effect of its depletion on mouse behavior, startle responses, muscular endurance, and body weight during development from postnatal day 0 (P0) until P60. In the elevated plus maze test, TauT-/- mice showed decreased anxiety-like behavior. In addition, TauT-/- mice did not show a startle response to startle stimuli, suggesting they have difficulty hearing. Wire-hang test revealed that muscular endurance was reduced in TauT-/- mice. Although a reduction of body weight was observed in TauT-/- mice during the developmental period, changes in body weight during 60% food restriction were similar to wild-type mice. Collectively, these results suggest that taurine has important roles in anxiety-like behavior, hearing, muscular endurance, and maintenance of body weight.	Watanabe, Miho\|Ito, Takashi\|Fukuda, Atsuo	[ { "bbox": "[53,122,107,134]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/metabo12070631	true	en	Life Sciences	529ec00a5b9de29c1d1ffd6d41cd24e01797fdf45d0cd082df2090a664459a78	Effects of Taurine Depletion on Body Weight and Mouse Behavior during Development
Lithium belongs to the critical elements and is used in a variety of high-tech applications. In the context of the circular economy, demand has arisen for technologies that are able to recover high-tech metals from wastes and byproducts. To achieve efficient recovery, apart from assessing metal enrichment, extensive knowledge of metal binding and leaching characteristics is required. The aim of the present study is to investigate the Li contents and mode of occurrence in Greek coal fly ashes. Eight coal fly ashes from different power plants in Greece were collected, and their major constituents were analyzed by X-ray fluorescence spectroscopy (XRF); their mineralogy was studied by X-ray powder diffraction (XRD), and their Li content was determined by ICP–MS. To identify Li binding and leaching characteristics, two sequential extraction methods (Tessier and BCR) were employed. The results showed that the Li content in the samples studied was between 95 and 256 μg/g and could be mainly attributed to the amorphous material encountered in the samples. The sequential extraction experiments revealed that 70–90% of Li is included in the residual fraction, indicating that it is strongly bound to the fly ash matrix.	Pentari, Despina\|Vlachaki, Eleftheria\|Fazaki, Maria Evangelia\|Stratakis, Antonios	[ { "bbox": "[53,122,107,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/su16041442	true	en	Earth and Atmospheric Sciences/Chemistry	a5d6c146461fb985e82df268cd8b26d3dd12defca7a32b3b233d1a68b79cbbb5	Lithium in Greek Coal Fly Ashes: Contents and Characterization by Sequential Extraction
	McManus, J. F.\|Menviel, L.\|Zhang, F.\|Ma, X.\|Marino, G.\|Yu, J.\|Piotrowski, A. M.\|Anderson, R. F.\|Rohling, E. J.\|Jian, Z.\|Jin, Z. D.	[ { "bbox": "[67,124,806,193]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1038/s41561-020-0610-5	true	en	Earth and Atmospheric Sciences	6f1522b20a11a6879d8fe761a1c28098c2f2ea1255ef1e3bedbfac4f261814bf	Last glacial atmospheric CO2 decline due to widespread Pacific deep-water expansion
	Adrian Liston\|Meryem Aloulou	[ { "bbox": "[57,205,789,247]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.imlet.2022.05.004	true	en	Life Sciences/Medicine and Health Sciences	91e4e60ce308141e21ce1734f8d2441d291ea2af61e76080b0fbd26dc1f3aa25	A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells
	Helen Onyeaka\|Taghi Miri\|KeChrist Obileke\|Abarasi Hart\|Christian Anumudu\|Zainab T. Al-Sharify	[ { "bbox": "[62,186,115,199]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.ccst.2021.100007	true	en	Energy and Power Science	9a8e89a696df66d57dc57dd895564033f92fd60a0991afb96a36465ea7ca8d96	Minimizing carbon footprint via microalgae as a biological capture
	Divya Nechiyil\|Jyoti Prakash\|Anusree Dey\|Rajath Alexander\|Sheetal Uppal\|Jitendra Bahadur\|Kinshuk Dasgupta	[ { "bbox": "[73,99,836,193]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1002/slct.202300029	true	en	Engineering and Manufacturing Science	b8a3817ca435e75baa06dd20627d6d3a08954c32e80ee2e9045cedf6797ecda2	A Highly Porous and Flexible Carbon Nanotube Array Coated with Gold Nanoparticles: Application in Non‐Enzymatic Ultrasensitive Detection and Monitoring of Blood/Saliva Glucose
In contrast with traditional control input design techniques based on mathematical models of the system, in data-driven control approaches, which have recently gained substantial attention, the controller is derived directly from the data that are collected from experiments or observations of the target system. In particular, several data-driven optimal control and model predictive control (MPC) techniques have been proposed. In this paper, it is shown that the recently proposed data-driven LQR (Linear Quadratic Regulator) has a stability margin that is the set of the uncertainties in the control input channels maintaining the closed-loop stability. As an application of the proposed stability margin of the data-driven LQR, the consensus problem is considered. Since the control design for the consensus of multi-agent systems can be reformulated into the robust stabilization of a linear system with uncertainty in the input channel, it is demonstrated that the derived stability margin can be used to design a controller for the consensus of multi-agent systems.	Umar, Abdul Aris\|Ryu, Kunhee\|Back, Juhoon\|Kim, Jung-Su	[ { "bbox": "[55,121,894,183]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/math12020199	true	en	Engineering and Manufacturing Science	71b7c15b323bc383e0ee7be5dd163e28863ba43458049c61fb301dfb9b11edd7	Stability Margin of Data-Driven LQR and Its Application to Consensus Problem
	Sikandar Aftab\|Hosameldin Helmy Hegazy\|Fahmid Kabir	[ { "bbox": "[82,85,685,116]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1002/admt.202201897	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	e769b45b34a56aa1740c737ed20528e3646ff2fc2696752ac0351540cab09a68	Emerging Trends in 2D Flexible Electronics
	Cobb, Johanna\|Craig, Wendy\|Richard, Janelle\|Snow, Elizabeth\|Turcotte, Heather\|Warters, Robert\|Quaye, Aurora	[ { "bbox": "[87,120,902,210]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1097/adm.0000000000000964	true	en	Medicine and Health Sciences	c87b008e3963fcaf03b5c82b036352a6faae66745ed72a40cb051eb0cf48ab0a	A Retrospective Study of Acute Postoperative Pain After Cesarean Delivery in Patients With Opioid Use Disorder Treated With Opioid Agonist Pharmacotherapy
	Zhou, Zhimin\|Ke, Song\|Wang, Rongquan\|Mayon, Robert\|Ning, Dezhi	[ { "bbox": "[57,122,105,135]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/app12062855	true	en	Engineering and Manufacturing Science/Earth and Atmospheric Sciences	8e28c3e91b27f6bbc57aecc8f098fb9d02b4be483d1a155c29ea21b91b2fc9d1	Hydrodynamic Investigation on a Land-Fixed OWC Wave Energy Device under Irregular Waves
	Miranda L. Aiken\|Macon J. Abernathy\|Michael V. Schaefer\|Ilkeun Lee\|Samantha C. Ying	[ { "bbox": "[82,135,914,181]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1021/acsearthspacechem.3c00141	true	en	Medicine and Health Sciences	f78a35e88481ce6f6a175edc9e36ea7e602ca8ad0b0fb961e9d6fb3cda853270	Inhibition of Chromium(III) Oxidation through Manganese(IV) Oxide Passivation and Iron(II) Abiotic Reduction
Context. We present observations of ZTF20aatqesi (SN 2020faa). This Type II supernova (SN) displays a luminous light curve (LC) that started to rebrighten from an initial decline. We investigate this in relation to the famous SN iPTF14hls, which received a great deal of attention and multiple interpretations in the literature, but whose nature and source of energy still remain unknown.Aims. We demonstrate the great similarity between SN 2020faa and iPTF14hls during the first 6 months, and use this comparison to forecast the evolution of SN 2020faa and to reflect on the less well observed early evolution of iPTF14hls.Methods. We present and analyse our observational data, consisting mainly of optical LCs from the Zwicky Transient Facility in the gri bands and of a sequence of optical spectra. We construct colour curves and a bolometric lc, and we compare ejecta-velocity and black-body radius evolutions for the two supernovae (SNe) and for more typical Type II SNe.Results. The LCs show a great similarity with those of iPTF14hls over the first 6 months in luminosity, timescale, and colour. In addition, the spectral evolution of SN 2020faa is that of a Type II SN, although it probes earlier epochs than those available for iPTF14hls.Conclusions. The similar LC behaviour is suggestive of SN 2020faa being a new iPTF14hls. We present these observations now to advocate follow-up observations, since most of the more striking evolution of SN iPTF14hls came later, with LC undulations and a spectacular longevity. On the other hand, for SN 2020faa we have better constraints on the explosion epoch than we had for iPTF14hls, and we have been able to spectroscopically monitor it from earlier phases than was done for the more famous sibling.	Yang, S.\|Sollerman, J.\|Chen, TW\|Kool, E. C.\|Lunnan, R.\|Schulze, S.\|Strotjohann, N.\|Horesh, A.\|Kasliwal, M.\|Kupfer, T.\|Mahabal, A. A.\|Masci, F. J.\|Nugent, P.\|Perley, D. A.\|Riddle, R.\|Rusholme, B.\|Sharma, Y.	[ { "bbox": "[161,156,833,180]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.1051/0004-6361/202039440	true	en	Astronomy and Space Sciences	1f276488b666a4f1cc3c7665a33500d438df6f70a5ae3bdd2b212a4e41a37e3a	Is supernova SN 2020faa an iPTF14hls look-alike?
We introduce a notion of expected utility for quantum tasks and discuss some general conditions under which this is increased by the presence of quantum noise in the underlying resource states. We apply the resulting formalism to the specific problem of playing the parity game with ground states of the random transverse-field Ising model. This demonstrates a separation in the ground-state phase diagram between regions where rational players will be ``risk-seeking'' or ``risk-averse'', depending on whether they win the game more or less often in the presence of disorder. The boundary between these regions depends non-universally on the correlation length of the disorder. Strikingly, we find that adding zero-mean, uncorrelated disorder to the transverse fields can generate a weak quantum advantage that would not exist in the absence of noise.	Shivaji L. Sondhi\|Chuqiao Lin\|Vir B. Bulchandani	[ { "bbox": "[297,64,707,82]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.48550/arxiv.2308.10969	true	en	Physics	2b1dace07262f6cd42527ad1b27060a2e99db72781d2ab050c8c6e95e01a8915	Quantum tasks assisted by quantum noise
	Sophie E. Kastberg\|Helene S. Lund\|Emanuella De Lucia-Rolfe\|Lydia U. Kaduka\|Michael K. Boit\|Eva Corpeleijn\|Henrik Friis\|Sophie Bernard\|Martine Paquette\|Alexis Baass\|Jon J. Rasmussen\|Dirk L. Christensen	[ { "bbox": "[70,136,855,223]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1111/tmi.13696	true	en	Medicine and Health Sciences	d3ad1fa6f55002a14276d2041166bb221465fe6866505e1a6385b90a683cb4e2	Hepatic steatosis is associated with anthropometry, cardio‐metabolic disease risk, sex, age and urbanisation, but not with ethnicity in adult Kenyans
	Jakob Olofsson	[ { "bbox": "[62,131,242,146]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1088/1757-899x/1281/1/012067	true	en	Engineering and Manufacturing Science	77431afe92168a3919e16eaada80ec2cad114315066399281ed13b977ee9bd22	Integrated fatigue life predictions of aluminium castings using simulated local microstructure and defects
	Caroline Huas\|Bruno Falissard\|Juliette Gueguen\|Massimiliano Orri	[ { "bbox": "[57,206,805,249]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.ctcp.2021.101380	true	en	Life Sciences	473eba4484a89be3bc30ab210624dc22f6134f760722e5ba78f815528035bcc6	Hypnosis for labour and childbirth: A meta-integration of qualitative and quantitative studies
In a previous work, we defined a novel HIV-1 fusion inhibitor peptide (E1P47) with a broad spectrum of activity against viruses from different clades, subtypes, and tropisms. With the aim to enhance its efficacy, in the present work we address the design and synthesis of several peptide amphiphiles (PAs) based on the E1P47 peptide sequence to target the lipid rafts of the cell membrane where the cell-cell fusion process takes place. We report the synthesis of novel PAs having a hydrophobic moiety covalently attached to the peptide sequence through a hydrophilic spacer of polyethylene glycol. Characterization of self-assembly in condensed phase and aqueous solution as well as their interaction with model membranes was analyzed by several biophysical methods. Our results demonstrated that the length of the spacer of polyethylene glycol, the position of the peptide conjugation as well as the type of the hydrophobic residue determine the antiviral activity of the construct. Peptide amphiphiles with one alkyl tail either in C-terminus (C-PAmonoalkyl) or in N-terminus (N-PAmonoalkyl) showed the highest anti-HIV-1 activities in the cellular model of TZM-bl cells or in a preclinical model of the human mucosal tissue explants.	Ramon Pons\|Isabel Haro\|Carolina Herrera\|Paul Ziprin\|Maria J Gómara	[ { "bbox": "[91,141,876,189]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1021/acs.bioconjchem.1c00292	true	en	Materials Science and Engineering/Medicine and Health Sciences	043b49472f6691ad993c32374523cdc29f9e01016c8d0f61f27d32990e490954	Peptide Amphiphilic-Based Supramolecular Structures with Anti-HIV-1 Activity
AimThe aim of the current study was to enlighten the evolution of prostate-specific membrane antigen (PSMA) expression in glioblastoma between initial diagnosis and recurrence in order to provide preliminary insight for further clinical investigations into innovative PSMA-directed treatment concepts in neuro-oncology.MethodsPatients who underwent resection for de-novo glioblastoma (GBM) and had a re-resection in case of a recurrent tumor following radiochemotherapy and subsequent chemotherapy were included (n = 16). Histological and immunohistochemical stainings were performed at initial diagnosis and at recurrence (n = 96 tissue specimens). Levels of PSMA expression both in endothelial and non-endothelial cells as well as vascular density (CD34) were quantified via immunohistochemistry and changes between initial diagnosis and recurrence were determined. Immunohistochemical findings were correlated with survival and established clinical parameters.ResultsPSMA expression was found to be present in all GBM tissue samples at initial diagnosis as well as in all but one case of recurrent tumor samples. The level of PSMA expression in glioblastoma varied inter-individually both in endothelial and non-endothelial cells. Likewise, the temporal evolution of PSMA expression highly varied in between patients. The level of vascular PSMA expression at recurrence and its change between initial diagnosis and recurrence was associated with post recurrence survival time: Patients with high vascular PSMA expression at recurrence as well as patients with increasing PSMA expression throughout the disease course survived shorter than patients with low vascular PSMA expression or decreasing vascular PSMA expression. There was no significant correlation of PSMA expression with MGMT promoter methylation status or Ki-67 labelling index.ConclusionPSMA is expressed in glioblastoma both at initial diagnosis and at recurrence. High vascular PSMA expression at recurrence seems to be a negative prognostic marker. Thus, PSMA expression in GBM might present a promising target for theranostic approaches in recurrent glioblastoma. Especially PSMA PET imaging and PSMA-directed radioligand therapy warrant further studies in brain tumor patients.	Jochen Herms\|Katja Steiger\|Friederike Liesche-Starnecker\|Adrien Holzgreve\|Lena Mittlmeier\|Maximilian A. Kirchner\|Annamaria Biczok\|Jürgen Schlegel\|Marcus Unterrainer\|Viktoria C. Ruf	[ { "bbox": "[290,216,885,395]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3389/fonc.2021.646387	true	en	Life Sciences	30d2624faa533039fcfb7b7767f26a828b5fa99d58afef872ee22ef97e5af57c	PSMA Expression in Glioblastoma as a Basis for Theranostic Approaches: A Retrospective, Correlational Panel Study Including Immunohistochemistry, Clinical Parameters and PET Imaging
	Saumitra Singh\|Mohd.Rahil Hasan\|Pradakshina Sharma\|Jagriti Narang	[ { "bbox": "[62,208,714,249]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.sintl.2022.100190	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	c66c77f98a88b928923037bba9dc1b142ff5537135f56e192097d5a105b62b93	Graphene nanomaterials: The wondering material from synthesis to applications
Some children hospitalized for severe pertussis need intensive care; moreover, some children die because of deterioration alone or in combination with other complications. The purpose of this study was to identify the mortality risk factors among hospitalized children with severe pertussis. This study evaluated the medical records of 144 hospitalized children with severe pertussis at the Guangzhou Women and Children’s Medical Centre between January 2016 and December 2019. The median age of patients was 2 months (IQR 1–4 months), with 90.3% of the patients aged < 6 months and 56.9% of the patients aged < 3 months. A total of 38 patients were admitted to intensive care unit (ICU), 13 patients died, and the mortality of severe pertussis was 34.2%, with patients younger than 6 weeks accounting for 76.9% of the deaths. On the multivariate analysis, the independent risk factors for death were WBC > 70.0 × 109/L (odds ratio [OR], 230.66; 95% confidence interval [CI], 5.16–10,319.09 P = 0.005) and pulmonary hypertension (PH) (OR 323.29; 95% CI 16.01–6529.42; P < 0.001). Severe pertussis mainly occurred in children aged < 3 months. The mortality of severe pertussis was 34.2%, with patients younger than 6 weeks accounting for the majority of the deaths. We recommend the first dose of diphtheria-tetanus-pertussis (DTP) should be advanced to the age of 2 months or even 6 weeks. The presence of a WBC > 70.0 × 109/L and PH were the prognostic independent variables associated with death.	Tingting Shi\|Ling Wang\|Shuling Du\|Huifeng Fan\|Minghua Yu\|Tao Ding\|Xuehua Xu\|Dongwei Zhang\|Li Huang\|Gen Lu	[ { "bbox": "[97,113,317,130]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1186/s12879-021-06732-1	true	en	Life Sciences	07b024569402e85b3b4433ec745a3bad6b27643292fdfab568166539dee47b1f	Mortality risk factors among hospitalized children with severe pertussis
	Matthew A. Young\|Nathan A. Schwadron\|Matthew Gorby\|Jon Linker\|Ronald M. Caplan\|Cooper Downs\|Tibor Török\|Pete Riley\|Roberto Lionello\|Viacheslav Titov\|Richard A. Mewaldt\|Christina M. S. Cohen	[ { "bbox": "[66,93,929,132]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.3847/1538-4357/abdf5f	true	en	Astronomy and Space Sciences	ab4315e41f8db99459bd65187f670e4bf5137b6940b7ee84597e84dbd20f6a5b	Energetic Proton Propagation and Acceleration Simulated for the Bastille Day Event of 2000 July 14
<div class="section abstract" id="abstract-1"><h2 class="">Abstract</h2><div id="sec-1" class="subsection"><p id="p-2"><strong>Summary</strong> We previously reported MCP-counter and mMCP-counter, methods that allow precise estimation of the immune and stromal composition of human and murine samples from bulk transcriptomic data, but they were only distributed as R packages. Here, we report webMCP-counter, a user-friendly web interface to allow all users to use these methods, regardless of their proficiency in the R programming language.</p></div><div id="sec-2" class="subsection"><p id="p-3"><strong>Availability and Implementation</strong> Freely available from <a href="http://134.157.229.105:3838/webMCP/">http://134.157.229.105:3838/webMCP/</a>. Website developed with the R package shiny. Source code available from GitHub: <a href="https://github.com/FPetitprez/webMCP-counter">https://github.com/FPetitprez/webMCP-counter</a>.</p></div></div>	Maxime Meylan, Etienne Becht, Catherine Sautès-Fridman, Aurélien de Reyniès, Wolf H. Fridman, Florent Petitprez	[ { "bbox": "[119,104,880,186]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.1101/2020.12.03.400754	true	en	Life Sciences	6a4d8254945bcafdece30e10dac913dc39e28f0c0ba4107cb47f4b1f547b2c82	webMCP-counter: a web interface for transcriptomics-based quantification of immune and stromal cells in heterogeneous human or murine samples
Hubei, Hunan and Henan Provinces are located in Central China, a region with extensive transport networks and trade. The pine wilt nematode (PWN), Bursaphelenchus xylophilus, the causative agent of pine wilt disease, is spread mainly through human activities. To further understand the genetic structure of PWN in Central China, we studied the genetic information of PWN populations in this region and compared the genetic relationship with strains from Guangdong and Jiangsu provinces. We found that the HB (Hubei) 15, HEN (Henan) 20, HN (Hunan) 07, HN08 and HN10 had significantly more SNPs and homozygotes than other strains from Central China, and their most frequent mutant genotypes also differed from other strains. The clustering results indicated that HB15, HEN 20, HN07, HN08 and HN10 were genetically distinct from other strains and closely related to Guangdong strains. We also observed significant genetic variation among strains in Henan province, suggesting that some of them might have different transmission sources than those from Hubei and Hunan provinces. Introgression analysis identified three possible pathways: (1) Guangdong to Henan; (2) Guangdong to Hunan; and (3) Jiangsu to Hubei. The results provide a basis for tracing the origin and spread of pine wood disease in China.	Tingting Chen\|Aixia Yang\|Xiaolei Ding\|Jianren Ye\|Yuan Feng	[ { "bbox": "[58,121,927,183]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/f14071443	true	en	Life Sciences	49d5964249b6d1ca6a8be2532f41f54336cb7b69bd58c22e77e46a997718ce7d	Genetic Diversity and Population Structure of Bursaphelenchus xylophilus in Central China Based on SNP Markers
In this study, we report a pH-responsive hydrogel-modified silicon nanowire field-effect transistor for pH sensing, whose modification is operated by spin coating, and whose performance is characterized by the electrical curve of field-effect transistors. The results show that the hydrogel sensor can measure buffer pH in a repeatable and stable manner in the pH range of 3–13, with a high pH sensitivity of 100 mV/pH. It is considered that the swelling of hydrogel occurring in an aqueous solution varies the dielectric properties of acrylamide hydrogels, causing the abrupt increase in the source-drain current. It is believed that the design of the sensor can provide a promising direction for future biosensing applications utilizing the excellent biocompatibility of hydrogels.	Li, Gangrong\|Wei, Qianhui\|Wei, Shuhua\|Zhang, Jing\|Jin, Qingxi\|Wang, Guozhi\|Hu, Jiawei\|Zhu, Yan\|Kong, Yun\|Zhang, Qingzhu\|Zhao, Hongbin\|Wei, Feng\|Tu, Hailing	[ { "bbox": "[53,122,105,134]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/nano12122070	true	en	Engineering and Manufacturing Science/Medicine and Health Sciences	91d855bcc211b6a7eb76ea22d8404054e3aa81e3d82f112ccdb6bff96c35eff1	Acrylamide Hydrogel-Modified Silicon Nanowire Field-Effect Transistors for pH Sensing
	Engle, Elizabeth C.\|Jabs, Ethylin W.\|Van Ryzin, Carol\|Collins, Francis S.\|Manoli, Irini\|Facio, Flavia M.\|Barry, Brenda S.\|Toro, Camilo\|Webb, Bryn D.\|Wu, Tianxia\|Joseph, Reversa\|Lehky, Tanya\|Gropman, Andrea	[ { "bbox": "[73,135,904,191]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1002/mus.27159	true	en	Medicine and Health Sciences	b2619386b296d181a9effea510946762eca2d7e9b36d2518fe9bd7f2439cfe16	Differentiating Moebius syndrome and other congenital facial weakness disorders with electrodiagnostic studies
We present here a new splitting method to solve Lyapunov equations in a Kronecker product form. Although this resulting matrix is of order $n^2$, each iteration demands two operations with the matrix $A$: a multiplication of the form $(A-\sigma I) \tilde{B}$ and a inversion of the form $(A-\sigma I)^{-1}\tilde{B}$. We see that for some choice of a parameter the iteration matrix is such that all their eigenvalues are in absolute value less than 1. Moreover we present a theorem that enables us to get a good starting vector for the method.	Licio Hernanes Bezerra\|Felipe Wisniewski	[ { "bbox": "[218,213,777,236]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.48550/arxiv.2309.12143	true	en	Mathematics and Computational Science	4a848fc43240e488d19213447d6ff9e7c9eb3439c4df4873f6d09a896dbe7638	An iterative method to solve Lyapunov equations
	Jong-Min Sohn\|Dong-Ju Lim	[ { "bbox": "[429,77,470,91]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1016/j.ijscr.2020.08.040	true	en	Medicine and Health Sciences	83442c91cdbe3fbfbbd71bb50612ea080eb0c18d8e7f76f2ec20ff2b4e81baad	Delayed symptomatic spinal adhesive arachnoiditis after surgery for thoracolumbar flexion-distraction injury
In December 2019, COVID-19 emerged in China, and in January 2020, the World Health Organization declared a state of international emergency. Within this context, there is a significant search for new drugs to fight the disease and a need for in vitro models for preclinical drug tests. This study aims to develop a 3D lung model. For the execution, Wharton's jelly mesenchymal stem cells (WJ-MSC) were isolated and characterized through flow cytometry and trilineage differentiation. For pulmonary differentiation, the cells were seeded in plates coated with natural functional biopolymer matrix as membrane until spheroid formation, and then the spheroids were cultured with differentiation inductors. The differentiated cells were characterized using immunocytochemistry and RT-PCR, confirming the presence of alveolar type I and II, ciliated, and goblet cells. Then, 3D bioprinting was performed with a sodium alginate and gelatin bioink in an extrusion-based 3D printer. The 3D structure was analyzed, confirming cell viability with a live/dead assay and the expression of lung markers with immunocytochemistry. The results showed that the differentiation of WJ-MSC into lung cells was successful, as well as the bioprinting of these cells in a 3D structure, a promising alternative for in vitro drug testing.	da Rosa, Nádia Nascimento\|Appel, Julia Maurer\|Irioda, Ana Carolina\|Mogharbel, Bassam Felipe\|de Oliveira, Nathalia Barth\|Perussolo, Maiara Carolina\|Stricker, Priscila Elias Ferreira\|Rosa-Fernandes, Lívia\|Marinho, Cláudio Romero Farias\|de Carvalho, Katherine Athayde Teixeira	[ { "bbox": "[53,122,107,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/ijms24065852	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	b4f4dc6695d40fc11adccb3235ab1176dc52ea11374cd6dfc24a4a0764d88b2a	Three-Dimensional Bioprinting of an In Vitro Lung Model
Nonlinear normal mode solutions of the beta-FPUT chain with fixed boundaries are presented in terms of the Jacobi sn function. Exact solutions for the two particle chain are found for arbitrary linear and nonlinear coupling strengths. Solutions for the N-body chain are found for the case of purely nonlinear couplings. Three distinct solution types are presented: a linear analogue, a chaotic amplitude mapping, and a localized nonlinear mode. The relaxation of perturbed modes are also explored using l(1)-regularized least squares regression to estimate the free energy functional near the nonlinear normal mode solution. The perturbed modes are observed to decay sigmoidally towards a quasi-equilibrium state and a logarithmic relationship between the perturbation strength and mode lifetime is found. (C) 2020 Elsevier B.V. All rights reserved.	Fuller, Nathaniel J.\|Sen, Surajit	[ { "bbox": "[68,222,788,266]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.physa.2020.124283	true	en	Physics	72fc6f829d7585747022a057cd7568fb2efc8c78e8bf9ba645ac3311f3dba4e1	Nonlinear normal modes in the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e307" altimg="si6.svg"><mml:mi>β</mml:mi></mml:math>-Fermi-Pasta–Ulam-Tsingou chain
	Hideyuki Ida\|Takuma Sato\|Yuta Rikukawa\|Reina Abe\|Shigeo Hoyano\|Toshikazu Tsuchimoto	[ { "bbox": "[70,108,907,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1111/1440-1703.12408	true	en	Medicine and Health Sciences	5c7af6a44e266bc28bd8aafd7115c611e7620ffe3f268506121d4ba4ef77370e	Optimizing species selection for the structural timbers of traditional farmhouses in a snowy rural area of northeastern Japan
We present the relativistic analogue of Anderson localization in one dimension. We use Dirac equation to calculate the transmission probability for a spin-½ particle incident upon a rectangular barrier. Using the transfer matrix formalism, we numerically compute the transmission probability for the case of a large number of identical barriers spread randomly in one dimension. The particular case when the incident particle has three component momentum and shows spin-flip phenomena is also considered. Our calculations suggest that the incident relativistic particle shows localization behaviour similar to that of Anderson localization. A number of results which are generalizations of the non-relativistic case are also obtained.	Mehta, Abhay\|Joshi, Sandeep\|Jain, Sudhir R.	[ { "bbox": "[77,94,205,110]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1140/epjb/e2019-100564-4	true	en	Physics	73ca48d315c4a2c5f9c8a7b17b91ffe8ae5a724fe9d77c121386b645eee6471f	Localization in one-dimensional relativistic quantum mechanics
	Colin Cook\|Pieter W. M. Bonnemaijer\|Hassan G. Hassan\|Anna J. Sanyiwa\|Nomdo M. Jansonius\|Valeria Lo Faro\|Hans G. Lemij\|Caroline C. W. Klaver\|Alberta A. H. J. Thiadens\|Suzanne Van de Laar	[ { "bbox": "[70,148,848,237]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1111/aos.14772	true	en	Medicine and Health Sciences	d406ace185bfc063bee557dc013804c1b256b2abbd7c87e303a246d2b4eed78b	Differences in clinical presentation of primary open‐angle glaucoma between African and European populations
	Huang Shiwen\|Zhao Kehan	[ { "bbox": "[90,182,875,230]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.rsci.2020.11.003	true	en	Life Sciences	f9dba0b00ac5792eb54fa463f9fba62029887f707a93dfcf839b8317e520cd0c	Different Hypotheses for Resistance Loss of Rice Varieties to Magnaporthe oryzae
Relativistic laser wakefield acceleration is characterized by an unsurpassed accelerating gradient, which is very suitable for electron acceleration over short distances and could be a promising candidate for next-generation compact accelerators. However, using this technique for positron acceleration is still challenging because positively charged particles are naturally defocused in nonlinear wakefields. Here we propose and numerically demonstrate a scheme to accelerate an externally injected positron beam in a nonlinear laser wakefield in a regime where a tail wave is formed behind density cusps of the wakefield. This tail wave can provide a focusing force in addition to longitudinal acceleration for the positrons. Three-dimensional particle-in-cell simulations demonstrate that a trapping efficiency of positrons of nearly 100% in the nonlinear wakefield is possible. This scheme may open a simple way for compact positron acceleration to multi-100 MeV with terawatt-class laser systems at high repetition rates without the need for special laser modes and plasma structures.	Feng He\|Xing-Long Zhu\|Zheng-Ming Sheng\|Jie Zhang\|Min Chen\|Wei-Yuan Liu\|Su-Ming Weng	[ { "bbox": "[169,63,831,82]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.48550/arxiv.2207.14749	true	en	Physics	c58ef4ec1c2979e02bbd2a7f8e608b82c71ecfba2a02be5fb5bf2e0feb931c36	Tail-wave-assisted Positron Acceleration in Nonlinear Laser Plasma Wakefields
	Zheng Han\|Ivan Naumkin\|Thierry Cazenave	[ { "bbox": "[66,223,722,270]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.na.2020.112243	true	en	Physics/Mathematics and Computational Science	7a0910da74dc28ac359d36130da8f0040e7a65045d9cd1cbecb3ca010639ddbc	Asymptotic behavior for a dissipative nonlinear Schrödinger equation
Glucocorticoids inhibit angiogenesis in the femoral head, which fails to nourish the bone tissue and leads to osteonecrosis. Restoring angiogenesis is not only essential for vessel formation, but also crucial for osteogenesis. Poly (L-lactic acid) (PLLA) is commonly used in the bone tissue engineering field. Panax notoginseng saponins (PNS) and osteopractic total flavone (OTF) promote angiogenesis and osteogenesis, respectively. We designed a sequentially releasing PLLA scaffold including PLLA loaded with OTF (inner layer) and PLLA loaded with PNS (outer layer). We assessed the osteogenic effect of angiogenesis in this scaffold by comparing it with the one-layered scaffold (PLLA embedded with OTF and PNS) in vivo. Results from the micro-CT showed that the data of bone mineral density (BMD), bone volume (BV), and percent bone volume (BV/TV) in the PO-PP group were significantly higher than those in the POP group (p < 0.01). Histological analyses show that the PO-PP scaffold exhibits better angiogenic and osteogenic effects compared with the one-layered scaffold. These might result from the different structures between them, where the sequential release of a bi-layer scaffold achieves the osteogenic effect of vascularization by initially releasing PNS in the outer layer. We further explored the possible mechanism by an immunohistochemistry analysis and an immunofluorescence assay. The results showed that the protein expressions of vascular endothelial growth factor (VEGF) and platelet endothelial cell adhesion molecule-1(CD31) in the PO-PP scaffold were significantly higher than those in the POP scaffold (p < 0.01); the protein expressions of osteocalcin (OCN), osteopontin (OPN), and alkaline phosphatase (ALP) in the PO-PP scaffold were significantly higher than those in the POP scaffold (p < 0.05). Upregulating the expressions of angiogenic and osteogenic proteins might be the possible mechanism.	Feng, Guiyu\|Zhang, Pingxin\|Huang, Jian\|Yu, Yao\|Yang, Fenghe\|Zhao, Xueqian\|Wang, Wei\|Li, Dongyang\|Sun, Song\|Niu, Xufeng\|Chai, Limin\|Li, Jinyu	[ { "bbox": "[58,124,107,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/jfb14010031	true	en	Medicine and Health Sciences	12b30878a2bf98dc943aad012d49d79f67da82f9756be9a9fdaf32df9fd2ee09	Sequential Release of Panax Notoginseng Saponins and Osteopractic Total Flavone from Poly (L-Lactic Acid) Scaffold for Treating Glucocorticoid-Associated Osteonecrosis of Femoral Head
	Nao Tahara\|Kentaro Hayashi\|Yukie Kanai\|Yoshie Kato\|Satoshi Abe\|Shingo Mitaki\|Atsushi Nagai	[ { "bbox": "[178,149,818,168]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3995/jstroke.10974	true	en	Medicine and Health Sciences	3d77c22603b410507894aaa29380924089a36afe9e20245198d1c5cbfe35ccbc	A case of bow hunter’s syndrome diagnosed by digital subtraction angiography kymograph
A medium chain-length polyhydroxyalkanoate (PHA) was produced by Pseudomonas mendocina CH50 using a cheap carbon substrate, sugarcane molasses. A PHA yield of 14.2% dry cell weight was achieved. Chemical analysis confirmed that the polymer produced was a medium chain-length PHA, a copolymer of 3-hydroxyoctanoate and 3-hydroxydecanoate, P(3HO-co-3HD). Lime oil, an essential oil with known antimicrobial activity, was used as an additive to P(3HO-co-3HD) to confer antibacterial properties to this biodegradable polymer. The incorporation of lime oil induced a slight decrease in crystallinity of P(3HO-co-3HD) films. The antibacterial properties of lime oil were investigated using ISO 20776 against Staphylococcus aureus 6538P and Escherichia coli 8739, showing a higher activity against the Gram-positive bacteria. The higher activity of the oil against S. aureus 6538P defined the higher efficiency of loaded polymer films against this strain. The effect of storage on the antimicrobial properties of the loaded films was investigated. After one-year storage, the content of lime oil in the films decreased, causing a reduction of the antimicrobial activity of the materials produced. However, the films still possessed antibacterial activity against S. aureus 6538P.	Basnett, Pooja\|Marcello, Elena\|Lukasiewicz, Barbara\|Nigmatullin, Rinat\|Paxinou, Alexandra\|Ahmad, Muhammad Haseeb\|Gurumayum, Bhavana\|Roy, Ipsita	[ { "bbox": "[126,117,174,130]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3390/jfb11020024	true	en	Materials Science and Engineering/Medicine and Health Sciences	72cebe97131d67ba3c9d06302aef7dfc851a63067a6acaf333d42be350f4814b	Antimicrobial Materials with Lime Oil and a Poly(3-hydroxyalkanoate) Produced via Valorisation of Sugar Cane Molasses
The sluggish kinetics of sulfur conversions have long been hindering the implementation of fast and efficient sulfur electrochemistry in lithium-sulfur (Li-S) batteries. In this regard, herein the unique chromium boride (CrB) is developed via a well-confined mild-temperature thermal reaction to serve as an advanced sulfur electrocatalyst. Its interstitial-alloy nature features excellent conductivity, while the nano-lamination architecture affords abundant active sites for host-guest interactions. More importantly, the CrB nanocatalyst demonstrates a dual sulphophilicity with simultaneous Cr─S and B─S bondage for establishing strong interactions with the intermediate polysulfides. As a result, significant stabilization and promotion of sulfur redox behavior can be achieved, enabling an excellent Li-S cell cyclability with a minimum capacity fading rate of 0.0176% per cycle over 2000 cycles and a favorable rate capability up to 7 C. Additionally, a high areal capacity of 5.2 mAh cm-2 , and decent cycling and rate performances are still attainable under high sulfur loading and low electrolyte dosage. This work offers a facile approach and instructive insights into metal boride sulfur electrocatalyst, holding a good promise for pursuing high-efficiency sulfur electrochemistry and high-performance Li-S batteries.	Hongyang Li\|Guxian Chen\|Kailong Zhang\|Liangbiao Wang\|Gaoran Li	[ { "bbox": "[85,93,805,180]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1002/advs.202303830	true	en	Engineering and Manufacturing Science	78884c41ea445b45463f9d7e0e2e5a3955240416d47e6be37420809c0acb5716	Dually Sulphophilic Chromium Boride Nanocatalyst Boosting Sulfur Conversion Kinetics Toward High‐Performance Lithium–Sulfur Batteries
Aim: This study determined the resistance pattern to beta-lactam antibiotics of bacteria isolated from goats with subclinical mastitis in Thika subcounty, Kenya. We also administered a questionnaire to assess the risk factors associated with the occurrence of resistance to commonly used antibiotics. Materials and Methods: We collected milk samples from 110 lactating dairy goats in Thika subcounty to screen for subclinical mastitis using the California mastitis test. Bacterial isolation and identification were performed according to colony morphology, the hemolytic pattern on sheep blood agar, lactose fermentation on MacConkey plates, Gram staining, and standard biochemical tests. The antibiotic susceptibility of the isolates was determined by the agar disk diffusion method using penicillin G, cephalexin, cefoxitin, and cefotaxime antibiotic disks. The double-disk synergy test using amoxicillin-clavulanic acid was employed as a confirmatory test for extended-spectrum beta-lactamase (ESBL) production. Fisher's exact test was used to determine the risk factors associated with the occurrence of antibiotic resistance (p <= 0.05 was considered significant). Results: Of the 110 dairy goats sampled, 72.7% (80) were positive for subclinical mastitis. Isolation and identification of the bacteria from the positive samples yielded 149 bacteria isolates, including Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter spp., Yersinia spp., coagulase-negative staphylococci, and Escherichia coli. A high percentage (76.5%, 114/149) of the bacterial isolates was resistant to at least one of the tested antibiotics. At least 56/106 isolates (52.8%) showing cross-resistance to the beta-lactam antibiotics were resistant to all four of the tested antibiotics, while only one isolate was resistant to three antibiotics (penicillin G, cephalexin, and cefoxitin). The double-disk synergy test confirmed that none of the isolates possessed ESBLs. Pre- and post-milking practices (p=0.0336) were found to be significantly associated with the occurrence of antibiotic resistance. Conclusion: A large proportion of the goats in our study cohort were infected with beta-lactam-resistant bacteria associated with subclinical mastitis. Because the identified bacteria are of zoonotic importance, further studies should be undertaken to determine the transmission dynamics between humans and livestock and to identify novel intervention strategies.	Okoko, Irene Mkavi\|Maina, Naomi\|Kiboi, Daniel\|Kagira, John	[ { "bbox": "[102,87,894,124]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.14202/vetworld.2020.1448-1456	true	en	Life Sciences	369d434cac028fd85354ecaa5dd9f1bccbb52e6a97611882824acb2c0277feaf	β-lactam resistance in bacteria associated with subclinical mastitis in goats in Thika Subcounty, Kenya
	Dylan R. Rice\|Kigocha Okeng'o\|Emmanuel Massawe\|Seif Ismail\|Notburga A. Mworia\|Faraja Chiwanga\|Boniface Kapina\|Michael Wasserman\|Farrah J. Mateen	[ { "bbox": "[116,95,881,146]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.jstrokecerebrovasdis.2021.106181	true	en	Medicine and Health Sciences	709b369b341bc41342d66bf0e05481cc2eaf8e0cefee2b643e05a4d585fa96ca	Efficacy of Fluoxetine for Post-Ischemic Stroke Depression in Tanzania
The study of shared variation in gray matter morphology may define neurodegenerative diseases beyond what can be detected from the isolated assessment of regional brain volumes. We, therefore, aimed to (1) identify SCNs (structural covariance networks) that discriminate between Alzheimer's disease (AD) patients and healthy controls (HC), (2) investigate their diagnostic accuracy in comparison and above established markers, and (3) determine if they are associated with cognitive abilities. We applied a random forest algorithm to identify discriminating networks from a set of 20 SCNs. The algorithm was trained on a main sample of 104 AD patients and 104 age-matched HC and was then validated in an independent sample of 28 AD patients and 28 controls from another center. Only two of the 20 SCNs contributed significantly to the discrimination between AD and controls. These were a temporal and a secondary somatosensory SCN. Their diagnostic accuracy was 74% in the original cohort and 80% in the independent samples. The diagnostic accuracy of SCNs was comparable with that of conventional volumetric MRI markers including whole brain volume and hippocampal volume. SCN did not significantly increase diagnostic accuracy beyond that of conventional MRI markers. We found the temporal SCN to be associated with verbal memory at baseline. No other associations with cognitive functions were seen. SCNs failed to predict the course of cognitive decline over an average of 18 months. We conclude that SCNs have diagnostic potential, but the diagnostic information gain beyond conventional MRI markers is limited.	Benno G Gesierich\|Florian Mayer\|Peter Dal-Bianco\|Christian Enzinger\|Stefan Ropele\|Reinhold Schmidt\|Fabian Wagner\|Marisa Koini\|Marco Duering	[ { "bbox": "[290,211,867,327]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3389/fpsyt.2020.00360	true	en	Life Sciences	9528a59226dc78cf4a2fa32c4b7ecec5c464be4d873be1aa94938df29350b36b	Gray Matter Covariance Networks as Classifiers and Predictors of Cognitive Function in Alzheimer’s Disease
Pre-eclampsia (PE) is usually defined as new-onset hypertension with albuminuria or other organ damage. Herein, the role and mechanism of long noncoding RNA (lncRNA) gastric carcinoma high expressed transcript 1 (GHET1) during PE are investigated. Expression of GHET1 in PE pregnancies was evaluated using quantitative real-time polymerase chain reaction (qRT-PCR). Proliferation and cell cycle of extravillous trophoblasts were assessed by Cell Counting Kit-8 (CCK-8), colony formation, 5-Ethynyl-2'-deoxyuridine (EdU) assays, and flow cytometry, respectively. Migration, invasion, and network formation of trophoblasts were measured by wound healing, transwell system, and tube formation assays. RNA immunoprecipitation (RIP), RNA pull-down, and chromatin immunoprecipitation (ChIP) assays were used to confirm the molecular interaction. GHET1 was markedly decreased in the placenta of PE patients. GHET1 promoted the proliferation and cell cycle of extravillous trophoblasts, as well as migration, invasion, and network formation in vitro. Metallothionein 2A (MT2A) functioned as a downstream effector of GHET1, which was negatively correlated with GHET1 in PE. GHET1 directly bound with zeste 2 polycomb repressive complex 2/lysine-specific demethylase 1 (EZH2/LSD1). Knockdown of GHET1 reduced the occupancies of H3K27me3 and H3K4me2 in the MT2A promoter region by recruiting EZH2 and LSD1. MT2A knockdown reversed GHET1 inhibition mediated biological functions. GHET1 regulates extravillous trophoblastic phenotype via EZH2/LSD1-mediated MT2A epigenetic suppression in PE.	Pengyun Wan\|Jia Huang\|Wenting Liu\|Xiaoyan Su\|Bei Zhao\|Xianggang Wang\|Lu Zhao	[ { "bbox": "[70,134,816,221]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1002/mrd.23693	true	en	Medicine and Health Sciences	59d6ce0dfc65b7672bdd997a8841f09dc82508fc88d2c55692aca5fcdc5e61cf	lncRNA GHET1 regulates extravillous trophoblastic phenotype via EZH2/LSD1‐mediated MT2A epigenetic suppression in pre‐eclampsia
We experimentally demonstrate the power scaling of optical vortices by the coherent beam combining, encompassing topological charges ranging from l=1 to l=5 realized on the basis of a Yb-doped fiber short-pulsed laser system. The combining efficiency varies from 83.2 to 96.9% depending on the topological charge and beam pattern quality generated by the spatial light modulators. These results open a pathway to high-intensity optical vortices with enormous potential applications in science and industry by utilizing advances in light-matter interactions.	Mikko Narhi\|Regina Gumenyuk\|Hossein Fathi	[ { "bbox": "[78,155,767,184]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.48550/arxiv.2312.09824	true	en	Physics	ac8b87d442924b3b7ed0d17e856e4d92a26768d1148c74906e737eda3257b428	Coherent beam combining of optical vortices
This article develops new tools and new statistical theory for a statistical problem we call Scale Reliant Inference (SRI). Many scientific fields collect multivariate data that lack scale: where the size, sum, or total of each measurement is arbitrary and is not representative of the scale of the underlying system being measured. For example, in the analysis of high-throughput sequencing data, it is well known that the number of sequencing reads (the sequencing depth) varies substantially due non-biological (technical) factors. This article develops a formal problem statement for SRI which unifies problems seen in multiple scientific fields. Informally, we define SRI as an estimation problem in which an estimand of interest cannot be uniquely identified due to the lack of scale information in the observed data. This problem statement represents a reformulation of the related field of Compositional Data Analysis and allows us to prove fundamental limits on SRI. For example, we prove that inferential criteria such as consistency, calibration, and bias are unattainable for common SRI tasks. Moreover, we show that common methods often applied to SRI implicitly assume infinite knowledge of the system scale and can lead to a troubling phenomena termed unacknowledged bias. Counter-intuitively, we show that this problem worsens with more data and can lead to substantially elevated Type-I and Type-II error rates. Still, we show that rigorous statistical inference is possible so long as models acknowledge the fundamental uncertainty in the system scale. We introduce a class of models we call Scale Simulation Random Variables (SSRVs) as flexible, rigorous, and computationally efficient approach to SRI.	Lawrence A. David\|Nicole A. Lazar\|Justin D. Silverman\|Jeffrey Letourneau\|Sayan Mukherjee\|Michelle Pistner Nixon	[ { "bbox": "[305,148,691,178]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.48550/arxiv.2201.03616	true	en	Mathematics and Computational Science	1e30c5c25ba1526d99c1371d2bbee48fd7f186a284b4b7814eb868e6877871df	Scale Reliant Inference
Classification of cardinal numerals is an important step in studying Chinese numerals. The study is carried out in the framework of the functional, structural (morphemic), and functional-structural (combined) classification approaches, as well as in accordance with the integrity of numerals and the accuracy of their quantifying properties. Chinese numerals are considered from the perspective of the first three classifications. The results obtained reveal the nomenclature volatility of Chinese cardinal numerals with the same classification group having several names to denote it. Hence, the article attempts to streamline the respective terminology. The functional classification divides cardinal numerals into coefficient and digit-position numerals. The cases when digit-position numerals may function as coefficient numerals are analyzed. In the framework of the structural classification, it is suggested to divide cardinal numerals into simple (coefficient) and compound ones, the latter being broken into additive (elementary and miscellaneous) and multiplicative. The article also focuses on answering the question of whether compound numerals should be regarded as words or phrases. The conclusion is made that they should be perceived as words. The functional-structural classification makes a substantial contribution to the study of Chinese cardinal numerals. The classification has not been introduced to the Russian sinology yet. This fact entails the necessity to translate the respective terms and expressions, the choice of which is explained in this article. The variations of the combined functional-structural classification introduced by Zhu Dexi, Guan Yanqìng, Xiao Guozheng, and Li Yingzhe are discussed. Based on the analysis of these variations, an understanding of the combined functional-structural division of Chinese cardinal numerals is suggested.	L.L. Bankova	[ { "bbox": "[184,165,487,181]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.26907/2541-7738.2021.4-5.175-193	true	en	Physics/Mathematics and Computational Science	8f5d40bf33ca719aec2295b1e02ad9917f742061cec44b571b0131efddf934ba	Functional, Structural, and Functional-Structural Classifications of Chinese Cardinal Numerals
	Pozzo, Federico\|Forestieri, Gabriela\|Ianna, Giulia\|Vit, Filippo\|Tissino, Erika\|Bittolo, Tamara\|Papotti, Robel\|Terzi DI Bergamo, Lodovico\|Steffan, Agostino\|Laureana, Roberta\|Tafuri, Agostino\|Chiarenza, Annalisa\|DI Raimondo, Francesco\|Olivieri, Jacopo\|Zaja, Francesco\|Laurenti, Luca\|Ilaria DEL Principe, Maria\|Bomben, Riccardo\|Zucchetto, Antonella\|Rossi, Davide\|Gattei, Valter	[ { "bbox": "[62,115,872,150]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1097/01.hs9.0000969280.78541.51	true	en	Life Sciences	2157901b6dad195a507494b410f4f0c7425c267101893206712e22190ae9ed55	P594: THE CXCR4-LOW/CD5-HIGH PROLIFERATIVE FRACTION IS ENRICHED IN BTK MUTATIONS AND ANTICIPATES RELAPSE IN IBRUTINIB-TREATED CLL
We say that a class $\mathcal{F}$ consisting of analytic functions $f(z)=\sum_{n=0}^{\infty} a_{n}z^{n}$ in the unit disk $\mathbb{D}:=\{z\in \mathbb{C}: \|z\|<1\}$ satisfies a Bohr phenomenon if there exists $r_{f} \in (0,1)$ such that $$ \sum_{n=1}^{\infty} \|a_{n}z^{n}\|\leq d(f(0),\partial f(\mathbb{D})) $$ for every function $f \in \mathcal{F}$ and $\|z\|=r\leq r_{f}$, where $d$ is the Euclidean distance. The largest radius $r_{f}$ is the Bohr radius for the class $\mathcal{F}$. In this paper, we establish the Bohr phenomenon for the classes consisting of Ma-Minda type starlike functions and Ma-Minda type convex functions as well as for the class of starlike functions with respect to a boundary point.	Vasudevarao Allu\|Himadri Halder	[ { "bbox": "[137,173,815,207]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.48550/arxiv.2006.15299	true	en	Mathematics and Computational Science	888c00add6b1726c5d300792c267556b72bdfe44651e075f7bf56c07b306c487	Bohr radius for certain classes of starlike and convex univalent\n functions
	Hallysson Oliveira\|Stiven S. Dias\|Marcelo G. S. Bruno	[ { "bbox": "[102,83,493,231]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1109/taes.2023.3333286	true	en	Engineering and Manufacturing Science	1d73c1e502507ba976c602be0000e1c02ae3c92fddb86fec4dd5e5fe6f9fa541	GNSS-Denied Joint Cooperative Terrain Navigation and Target Tracking Using Factor Graph Geometric Average Fusion
This volume covers topics in the research area of birational geometry and moduli spaces, including irreducible holomorphic symplectic manifolds, Severi varieties, degeneration of Calabi-Yau varieties, toric Fano threefolds, mirror symmetry, canonical bundle formula, the Lefschetz principle and more.	Colombo, Elisabetta\|Fantechi, Barbara\|Frediani, Paola\|Iacono, Donatella\|Pardini, Rita	[ { "bbox": "[91,136,851,260]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1007/978-3-030-37114-2	true	en	Physics/Mathematics and Computational Science	7561d046ed67875a9a772864c664bcf81e8f52b54fec318e50f234af35ed384e	Birational Geometry and Moduli Spaces
In the 21st century, the world is faced with COVID-19 global pandemic that has had wide-ranging health, social, food, and economic negative impacts throughout the world and also in Indonesia due to the cessation of the mobility of most people and economic engines. The creative empowers the community based on innovation and creativity proven and is one of the pillars of disaster risk reduction recovering the social and economic impact of COVID-19 in the community. The method used is an ethnographic approach starting from the collection of literature sources and supported by field data. The results show that the concept of the creative economy is creative ideas developed by humans supported by the use of technology to produce innovative products and cultures, having regional imagery but are globally competitive and can ultimately provide value to the national economy. Intellectual actors included are not only academics but also include industry players, pioneers, figures in the arts, culture, and sciences who have a role in providing creative ideas, innovations in the creative industry. The result is a triplex helix model in mitigating the effect of the covid19 disaster by connecting intellectuals, businesses, and the government in a creative economic structure.	Ratna W.D.P\|Rizal Noviansyah\|Riza B.S\|Fauziyah\|Dimyati Muhammad	[ { "bbox": "[129,156,919,200]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.1051/e3sconf/202133104015	true	en	Medicine and Health Sciences	20180ba16227f0984fd2f416b303cb0c92521f496fad34dfbd9e42d2c7bcac4c	Empowering community through creative economy as a disaster risk reduction strategy in Indonesia
The exoplanet detection is the most exciting and challenging field of astronomy. The discovery of many exoplanets has revolutionized our understanding of the formation and evolution of planetary systems and has showed new ways to search for extra terrestrial life. In recent years, some primary methods of exoplanet detection like transit, radial velocity, gravitational microlensing, direct imaging and astrometry have played a important role for the discovery of exoplanets. In this paper we explored detection methodologies with all the implications and analytics of comparison between them. Here we also discussed on different machine learning algorithms for exoplanet detection and visualization. Finally, concluded with the significant discoveries made by some missions and their implications on our understanding for the properties, environmental conditions and importance of exoplanets in the universe.	Aditee Mattoo\|Mahima Kaushik\|Ritesh Rastogi	[ { "bbox": "[80,146,561,167]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.48550/arxiv.2404.09143	true	en	Astronomy and Space Sciences	baf0e88adad52a008cb200df427e5a16b76cb905ee49fac8c21704da4fe6a3cb	Exoplanet Detection : A Detailed Analysis
	Hiroshi Arima\|Shintaro Iwama	[ { "bbox": "[85,137,866,182]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.2169/naika.109.705	true	en	Medicine and Health Sciences	04139ef8560986b64a12d4884c5c520b2e4e30068f4e39a60453a4d7cb0dc3b9	I. Hyponatremia Associated with Endocrine Diseases
Acute mountain sickness (AMS) is caused by rapid ascent to altitude (>2500 m) and remains a poorly understood pathophysiological condition. Accordingly, we investigated the relationship between acute exposure to high altitude and hypoxia related biochemical proteins. 21 healthy subjects (Female (8) and male (13), Age: 36.7±8.5, BMI: 23.2±3.1) volunteers participated in this project and fasting blood samples were taken before (sea level) and after 1 and 24-h exposure to high altitude (3,550 m). Blood oxygen saturation (SpO2), AMS status (Lake Louise Score) and serum HIF-1, Endothelin-1, VEGF and Orexin-A were measured (via ELISA) at 1, 6 and 24 h after exposure to high altitude. Pre-ascent measurement of hypoxia related proteins (Orexin-A, HIF-1, VEGF and Endothelin-1) where all significantly (<0.05) higher in the AMS-resistant individuals (No-AMS) when compared to AMS susceptible individuals (AMS+). Upon ascent to high altitude, 11 out of 21 volunteers had AMS (10.1±0.6 in AMS+ vs. 0.9±0.6 in No-AMS, P<0.05) and presented with lower resting SpO2 levels (77.7±0.4 vs. 83.5±0.3 respectively, p<0.05). Orexin-A, HIF-1, VEGF and Endothelin-1, significantly increased 24 hrs after exposure to high altitude in both AMS+ and No-AMS. The response of Orexin-A was similar between two groups, also, HIF-1 elevation 24 hrs after exposure to altitude was more in AMS+ (13% vs. 19%), but the increase of VEGF and Endothelin-1, 1 and 24 hrs after exposure to altitude in No-AMS was double that of AMS+. Hypoxia related proteins include Orexin-A, HIF-1, VEGF and Endothelin-1 may play a pathophysiological role in those who are susceptible to AMS.	Bayan Fayazi\|Kamal Ranjbar\|Vahid Tadibi	[ { "bbox": "[53,352,148,422]", "code_body": null, "code_caption": null, "image_caption": "[]", "image_footnote": "[]", "img_path": "images/0584/2695b840c0f8f1aa4490b37234c886f48b048501e6d1a782eaa96262a39cb324.jpg", "list_items": null, "page_idx": "0", "sub_type": null, "table_...	10.1371/journal.pone.0292173	true	en	Life Sciences	34cbb6715a8d26986a47357bc56300d5aa490763f16894ac2e9d92b1abcbcbd6	The role of hypoxia related hormones responses in acute mountain sickness susceptibility individuals unaccustomed to high altitude
This paper aims to map the daily functional characteristics of people diagnosed with essential tremor (ET) based on their subjective self-reports. In addition, we provide objective measurements of a cup-drinking task. This study involved 20 participants diagnosed with ET who completed the Columbia University Assessment of Disability in Essential Tremor (CADET) questionnaire that included five additional tasks related to digital equipment operation we wrote. Participants also described task-performance modifications they implemented. To create objective personal performance profiles, they performed a cup-drinking task while being monitored using a sensor measurement system. The CADET's subjective self-report results indicate that the most prevalent tasks participants reported as having difficulty with or requiring modifications were writing, threading a needle, carrying a cup, using a spoon, pouring, and taking a photo or video on a mobile phone. Analysis of participants' modifications revealed that holding the object with two hands or with one hand supporting the other were the most prevalent types. No significant correlation was found between the CADET total scores and the cup drinking objective measures. Capturing patients' perspectives on their functional disability, alongside objective performance measures, is envisioned to contribute to the development of custom-tailored interventions aligned with individual profiles, i.e., patient-based/smart healthcare.	Rosenblum, Sara\|Salih, Adham\|Roth, Navit	[ { "bbox": "[53,122,107,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/s24154854	true	en	Medicine and Health Sciences	e8dbf18411e9cb7a9f311ac0b7235b19f2e117d7fab2ed676a45c0a7781768f7	Subjective and Objective Day-to-Day Performance Measures of People with Essential Tremor
		[ { "bbox": "[312,85,685,112]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1021/acsami.1c02562.s001	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	e71e476234fb054ec68b409108f23ae14375acdb07d704e0f41a07a0a3a00d2b	Enhanced\nTriboelectric Nanogenerator Based on Tungsten\nDisulfide via Thiolated Ligand Conjugation
Background Axial spondyloarthritis (AxSpA) produces structural changes that cause alterations in body functions. One tissue that seems to have a predictive role in the etiology and progression of the disease is the soft tissue, particularly the fascia. However, little is known about the use of myofascial induction in people with AxSpA, and clinical evidence from physiotherapy regarding potential strategies is limited. Objective To evaluate the efficacy of myofascial induction compared with its simulation on joint amplitude in people with AxSpA. Methods In this randomized controlled parallel superiority clinical trial, 84 people with an AxSpA diagnosis confirmed by a rheumatologist will be randomly assigned to groups: the experimental group or the control group. The experimental group will receive myofascial induction, and the control group will undergo a simulation of the technique. Both groups will receive an examination session and six intervention sessions twice per week for three weeks. A baseline follow-up will be performed immediately after the intervention and four weeks after treatment. Conclusion The results of this study may contribute to a better understanding of the efficacy of myofascial induction for joint mobility in people with AxSpA. The implications of these results have a potential transformative effect on the understanding, analysis, evaluation, and physiotherapeutic treatment of this health condition.	Sanchez Vera, Maria Alejandra\|Jaimes Fernandez, Diego Alejandro\|Schleip, Robert	[ { "bbox": "[325,116,446,130]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.1371/journal.pone.0286885	true	en	Medicine and Health Sciences	f2166330a919a23067c737577790b6f11d5f3ceb4d50e09c7406036ed4ebd937	Efficacy of myofascial induction compared with its simulation on joint amplitude in people with axial spondylarthritis: Protocol of a randomized controlled clinical trial
PurposeIntensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT), two advanced modes of high-precision radiotherapy (RT), have become standard of care in the treatment of head and neck cancer. The development in RT techniques has markedly increased the complexity of target volume definition and accurate treatment delivery. The aim of this study was to indirectly investigate the quality of current TV delineation and RT delivery by analyzing the patterns of treatment failure for head and neck cancer patients in our high-volume RT center.MethodsBetween 2004 and 2014, 385 patients with pharyngeal, laryngeal, and oral cavity tumors were curatively treated with primary RT (IMRT/VMAT). We retrospectively investigated locoregional recurrences (LRR), distant metastases (DM), and overall survival (OS).ResultsMedian follow-up was 6.4 years (IQR 4.7–8.3 years) during which time 122 patients (31.7%) developed LRR (22.1%) and DM (17.7%). The estimated 2- and 5-year locoregional control was 78.2% (95% CI 73.3, 82.3) and 74.2% (95% CI 69.0, 78.8). One patient developed a local recurrence outside the high-dose volume and five patients developed a regional recurrence outside the high-dose volume. Four patients (1.0%) suffered a recurrence in the electively irradiated neck and two patients had a recurrence outside the electively irradiated neck. No marginal failures were observed. The estimated 2- and 5-year DM-free survival rates were 83.3% (95% CI 78.9, 86.9) and 80.0% (95% CI 75.2, 84.0). The estimated 2- and 5-year OS rates were 73.6% (95% CI 68.9, 77.8) and 52. 6% (95% CI 47.3, 57.6). Median OS was 5.5 years (95% CI 4.5, 6.7).ConclusionTarget volume definition and treatment delivery were performed accurately, as only few recurrences occurred outside the high-dose regions and no marginal failures were observed. Research on dose intensification and identification of high-risk subvolumes might decrease the risk of locoregional relapses. The results of this study may serve as reference data for comparison with future studies, such as dose escalation or proton therapy trials.	Julie van der Veen\|Annouschka Laenen\|Heleen Bollen\|Sandra Nuyts	[ { "bbox": "[290,240,847,297]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3389/fonc.2021.720052	true	en	Medicine and Health Sciences	e3bd3967d7f8d7b67cfda2611d85b2f3fef1a34ea8e02db2d60cf7cbe65053f7	Recurrence Patterns After IMRT/VMAT in Head and Neck Cancer
	Michael Perch\|Isabelle Opitz\|Mateja Ladan\|Laura-Chiara Guglielmetti\|Henrik Jessen Hansen\|Didier Schneiter\|Daniel Franzen\|Walter Weder\|Claudio Caviezel	[ { "bbox": "[88,83,910,108]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1093/icvts/ivaa261	true	en	Medicine and Health Sciences	ea39a50f89f95e431fa3d47ed579a5eb5bae40f3b65e8677730eef4880592c6c	Lung volume reduction surgery as salvage procedure after previous use of endobronchial valves
	Darwis\|P Didiansari\|Y Lumoindong\|E B Demmallino\|M A Ramlan	[ { "bbox": "[60,131,243,144]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1088/1755-1315/807/3/032065	true	en	Life Sciences	7199d745246bd85537f4ee97a97b447361acc48d727f71291b4740eea7099edf	Effectiveness of the Bansos Rastra distribution program in Kajang District, Bulukumba Regency
Restoration of the locomotor function is one of the most essential problems of medicine. This problem becomes especially essential, when we deal with those children, who can't walk from their birth. Term “abilitation” is used just in relation to such children, what means not retraining children the right stereotype of walking, but appearance of this skill and its further adequate development. Nowadays, more and more specialists, who occupy themselves with abilitation of children of the early age, realize necessity of the instrumental estimation of the locomotor function. This phenomenon is connected with the fact, that in contrast with the score system of estimation, instrumental estimation of walking is maximally concrete and exact, and complex investigation of the biomechanical and innervative structure of walking gives complete idea of the locomotor disturbances of the child. Authors of this article investigated biomechanical and innervative structure of walking of 4 healthy children at the age of 2-2.5 years. On the basis of these investigations, it has been revealed, that the following peculiarities of walking are characteristic of children at the age of 2: remarkable diminution of the mean walking velocity, increase of cadence and shortening of the step length, essential transformation of the temporal structure of walking (growth of duration of the stance and double-support phase and decrease of duration of the swing phase), flexion position of the lower extremities, displacement of all extreme values of the angular displacements to the right along the temporal axis, considerable prolongation of the maximums of activity, absence of the second maximum of activity in a number of muscles, severe disturbances in the resonance properties of the lower extremities. All these peculiarities point out to the immaturity of the process of locomotion in children at the age of 2. The received data are necessary first of all as the standard ones, because walking parameters of children with the locomotor disorders of the early age must be compared with the corresponding parameters of the healthy children of the same age. © 2021. Batysheva T.T., Pismennaya E.V., Petrushanskaya K.A., Pisareva M.V., Kovina M.V. All Rights Reserved.	Batysheva, T.T.\|Pismennaya, E.V.\|Petrushanskaya, K.A.\|Pisareva, M.V.\|Kovina, M.V.	[ { "bbox": "[196,192,848,247]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.15593/rjbiomech/2021.4.08	true	en	Medicine and Health Sciences	4a0f94976542a2c1c001039e99cd3be6deb7651e96e5e0e8e660670c6360c6d5	Peculiarities of the biomechanical and innervative structure of walking of healthy children of the early age
	Geneviève Morneau-Vaillancourt\|Olakunle Oginni\|Elham Assary\|Georgina Krebs\|Ellen J. Thompson\|Elisavet Palaiologou\|Celestine Lockhart\|Louise Arseneault\|Thalia C. Eley	[ { "bbox": "[90,91,909,171]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1111/jcpp.13847	true	en	Medicine and Health Sciences	4a4a2de95dd90ac2a7cd58f7feb8bd850a4a627c74cf0b0591144b0e7d88fd0c	A cross‐lagged twin study of emotional symptoms, social isolation and peer victimisation from early adolescence to emerging adulthood
	Wenjun Liao\|Jinlan He\|Xiangde Luo\|Mengwan Wu\|Yuanyuan Shen\|Churong Li\|Jianghong Xiao\|Guotai Wang\|Nianyong Chen	[ { "bbox": "[57,153,328,174]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.ijrobp.2022.03.031	true	en	Medicine and Health Sciences	53000e0347e136c3b694f691e89c17fff7be29dd2f21ba3eb2cc3e20ff36c6ad	Automatic Delineation of Gross Tumor Volume Based on Magnetic Resonance Imaging by Performing a Novel Semisupervised Learning Framework in Nasopharyngeal Carcinoma
	Sven-Erik Sönksen\|Sven Kühn\|Mathias Basner\|Darius Gerlach\|Fabian Hoffmann\|Christian Mühl\|Jens Tank\|Hans-Jürgen Noblé\|Katja Akgün\|Tjalf Ziemssen\|Jens Jordan\|Ulrich Limper	[ { "bbox": "[72,136,924,193]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1111/ene.15470	true	en	Life Sciences	71e58b13d4fd9edd1146b8571054b7cbc5b9375945c6d8fa4d0e2884b5210c5e	Brain structure and neurocognitive function in two professional mountaineers during 35days of severe normobarichypoxia
	V A Devisilov\|N P Frolov	[ { "bbox": "[60,131,243,144]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1088/1755-1315/815/1/012008	true	en	Engineering and Manufacturing Science	91766d7913abcd12c48ece958e51eed1a7fea5fb032e4f231f7d41aa122eba3b	Investigation of the pressure drop on the filtration and protective baffles of a hydrodynamic vibration filter using ANSYS CFX
PURPOSE Oncologists are increasingly using molecular profiling to inform personalized patient treatment decisions. Despite its promising utility, the integration of genomic testing into diverse clinical health care settings across geographic settings has been understudied. METHODS We used data from the National Survey of Precision Medicine in Cancer Treatment, a nationally representative sample of practicing US oncologists, to assess the availability of six genomic testing resources, including on-site pathology, contracts with outside laboratories, on-site genetic counselors, internal policies or protocols for using genomic and biomarker testing, electronic medical record alerts, and genomic or molecular tumor boards. We used multivariate logistic regression models to examine differences in the availability of each genomic testing resource by practice type and rurality while adjusting for payer mix and patient volume. RESULTS A larger proportion of multispecialty group and academic practices had genomic testing resources available compared with solo and nonacademic practices. Electronic medical record alerts were the least available resource, whereas contracts with outside laboratories were the most available resource. Compared with urban practices, there were significantly fewer practices located in rural areas that had on-site pathology, on-site genetic counselors, protocols for genomic tests, and molecular tumor boards. CONCLUSION Genomic testing resources varied by practice type and geography among a nationally representative sample of practicing oncologists. This variation has important implications for the development of interventions and policies to support the more equitable delivery of precision oncology to patients with cancer.	Gardner, Brittany\|Doose, Michelle\|Sanchez, Janeth, I\|Freedman, Andrew N.\|de Moor, Janet S.	[ { "bbox": "[193,56,902,154]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1200/po.21.00109	true	en	Medicine and Health Sciences	57454066d82c8ffeed38438a64f9f8e5471ab7b54d6b210199cdc0be0ea64fcb	Distribution of Genomic Testing Resources by Oncology Practice and Rurality: A Nationally Representative Study
	Andrade, Mônica Viegas\|Noronha, Kenya\|Cardoso, Clareci Silva\|Oliveira, Cláudia Di Lorenzo\|Calazans, Júlia Almeida\|Souza, Michelle Nepomuceno	[ { "bbox": "[67,126,670,215]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1590/1414-462x202199010302	true	pt	Medicine and Health Sciences	3e7662a9afcc0f8dd34a931ffdd207912ba4a321502b48b43ed33a4a81707714	Análise da concordância entre as informações reportadas pelas mães e dos cartões de vacina das crianças no Brasil (2013 e 2015)
Repeated exposure to psychostimulants such as methamphetamine (METH) induces neuronal adaptations in the mesocorticolimbic dopamine system, including the ventral tegmental area (VTA). These changes lead to persistently enhanced neuronal activity causing increased dopamine release and addictive phenotypes. A factor contributing to increased dopaminergic activity in this system appears to be reduced GABAB receptor-mediated neuronal inhibition in the VTA. Dephosphorylation of serine 783 (Ser783) of the GABAB2 subunit by protein phosphatase 2A (PP2A) appears to trigger the downregulation GABAB receptors in psychostimulant-addicted rodents. Therefore, preventing the interaction of GABAB receptors with PP2A using an interfering peptide is a promising strategy to restore GABAB receptor-mediated neuronal inhibition. We have previously developed an interfering peptide (PP2A-Pep) that inhibits the GABAB receptors/PP2A interaction and thereby restores receptor expression under pathological conditions. Here, we tested the hypothesis that restoration of GABAB receptor expression in the VTA of METH addicted mice reduce addictive phenotypes. We found that the expression of GABAB receptors was significantly reduced in the VTA and nucleus accumbens but not in the hippocampus and somatosensory cortex of METH-addicted mice. Infusion of PP2A-Pep into the VTA of METH-addicted mice restored GABAB receptor expression in the VTA and inhibited METH-induced locomotor sensitization as assessed in the open field test. Moreover, administration of PP2A-Pep into the VTA also reduced drug seeking behavior in the conditioned place preference test. These observations underscore the importance of VTA GABAB receptors in controlling addictive phenotypes. Furthermore, this study illustrates the value of interfering peptides targeting diseases-related protein-protein interactions as an alternative approach for a potential development of selective therapeutic interventions.	Mohammad Hleihil\|Dietmar Benke	[ { "bbox": "[80,143,105,159]", "code_body": null, "code_caption": null, "image_caption": "[]", "image_footnote": "[]", "img_path": "images/0992/acc6bafecea79aec229a67bafe80c48930a0b71066d4004adc645aa5f4abaa2d.jpg", "list_items": null, "page_idx": "0", "sub_type": null, "table_...	10.3389/fnmol.2024.1347228	true	en	Life Sciences	1111549b953075c85ee3512da3032ccfb4589faa960614ed82e8a7bef365bad6	Restoring GABAB receptor expression in the ventral tegmental area of methamphetamine addicted mice inhibits locomotor sensitization and drug seeking behavior
	Bo Xiu\|Rui Zhang\|Aijia Shang\|Fuyun Liu	[ { "bbox": "[91,129,903,178]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.26599/jnr.2020.9040010	true	en	Medicine and Health Sciences	26b3e527d743839518922e4db5a0cfb413ec7ffebe4e6bb32d453182040cc375	Chinese expert consensus on diagnosis and management of split cord malformation
The mucilage extracted from the convection-dried cladodes of O. ficus-indica and O. joconostle, two species of economic importance, delivered three fractions after methanol precipitation. Two were composed of high molar mass polysaccharides, and one included water-soluble mono-, di-, and oligosaccharides. The large polysaccharides have a molar mass range of 4.0 x 10(3) to 8.0 x 10(5) g.mol(-1) and are consistently composed of galactose, arabinose, xylose, and rhamnose;however, the content of galacturonic acid was different between both fractions and species. Their fermentability by selected probiotics was relatively low, 11-27 % compared to glucose, and decreased with increasing levels of galacturonic acid in the molecules. In the third fraction, previously unreported oligosaccharides were found. These include simple- and complex-structured galactooligosaccharides with arabinosyl-, xylosyl- and galacturonosyl acid residues. Their fermentability by prebiotic species can be ascribed more to their structural characteristics and monosaccharide composition than their molecular dimensions.	CruzRubio, Jose M.\|Mueller, Monika\|Viernstein, Helmut\|Loeppert, Renate\|Praznik, Werner	[ { "bbox": "[57,206,744,269]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.foodchem.2021.130167	true	en	Life Sciences	9f0766dba8fa90cc280bd8d2a9ecaf7031fb89fe20c30782c3b633a5124b11e9	Prebiotic potential and chemical characterization of the poly and oligosaccharides present in the mucilage of Opuntia ficus-indica and Opuntia joconostle
	John C. Boik	[ { "bbox": "[127,117,684,179]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3390/su12176881	true	en	Mathematics and Computational Science	4b38b07441de1e1020d460537dc87777b3856056107e143e6e645a799c1db7d9	Science-Driven Societal Transformation, Part I: Worldview
Low back pain caused by disc herniation and spinal stenosis imposes an enormous medical burden on society due to its high prevalence and refractory nature. This is mainly due to the long-term inflammation and degradation of the extracellular matrix in the process of intervertebral disc degeneration (IVDD), which manifests as loss of water in the nucleus pulposus (NP) and the formation of fibrous disc fissures. Biomaterial repair strategies involving hydrogels play an important role in the treatment of intervertebral disc degeneration. Excellent biocompatibility, tunable mechanical properties, easy modification, injectability, and the ability to encapsulate drugs, cells, genes, etc. make hydrogels good candidates as scaffolds and cell/drug carriers for treating NP degeneration and other aspects of IVDD. This review first briefly describes the anatomy, pathology, and current treatments of IVDD, and then introduces different types of hydrogels and addresses “smart hydrogels”. Finally, we discuss the feasibility and prospects of using hydrogels to treat IVDD.	Zhangheng Huang\|Chuan Guo\|Zhen Zhao\|Zhe Wang\|Qingquan Kong\|Yuheng Liu\|Fei Ma\|Weifei Zhang\|Yu Wang	[ { "bbox": "[80,156,104,173]", "code_body": null, "code_caption": null, "image_caption": "[]", "image_footnote": "[]", "img_path": "images/0759/b4db2df67ce29bf1d4f66485e9cdeb286167f52a823bdb143483e5e83de5d62f.jpg", "list_items": null, "page_idx": "0", "sub_type": null, "table_...	10.3389/fcell.2023.1286223	true	en	Medicine and Health Sciences	a307f3d9de58485a3dcfe97dfefc6c1352f423391d5e3e3151ddbde502b19b40	Application and development of hydrogel biomaterials for the treatment of intervertebral disc degeneration: a literature review
	Snehal Jain\|Naresh Kumar Thanigaivel\|Pablo Valdivia y Alvarado\|Naresh D. Sanandiya\|Vincent Sebastian Joseph\|Thileepan Stalin\|Theo Calais	[ { "bbox": "[57,206,796,252]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.apmt.2021.100979	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	8ae481ce175c109a7aa43ff7802f73e08f1a4defba9c27aaffeece77fac2aa16	Silicone/epoxy hybrid resins with tunable mechanical and interfacial properties for additive manufacture of soft robots
Biometric seed analysis can be used to characterize and differentiate forest species. However, forest species are generally studied using manual methods such as measurements with a digital caliper, which provides a limited amount of information on plant morphological characteristics, whereas agronomic species are analyzed using expensive and often inaccessible equipment. Thus, the objective of the present study was to demonstrate that seed image analysis and processing tools can help characterize and differentiate Brazilian forest species. For this purpose, the seeds of 155 forest species belonging to 42 families were photographed and analyzed to extract data on their morphometric descriptors using a new methodological approach. A total of 18 characteristics were assessed, namely eight dimensions, four shape characteristics, and six color characteristics. A set of approximately 1.827 million data was extracted from 101,521 seed images. Digital image processing efficiently characterized the studied seeds and the obtained characteristics allowed us to differentiate between species, including those belonging to the same botanical family and genus. Therefore, seed image analysis using the proposed methodology can be used to characterize, differentiate, and automatedly identify forest species in Brazil.	Felix, Francival Cardoso\|Kratz, Dagma\|Ribeiro, Richardson\|Nogueira, Antonio Carlos	[ { "bbox": "[94,164,173,181]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.5902/1980509873427	true	en	Life Sciences	b2d8404c306bc8bb0fa0bf57cfb1aaee991e4b5452b7598cd1775398af996685	Characterization and differentiation of forest species by seed image analysis: a new methodological approach
	Qing Deng\|Ning Yang\|Na Yang	[ { "bbox": "[81,167,278,190]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1155/2022/6355098	true	en	Engineering and Manufacturing Science	981fc4d3a47fa6d2db9ad72394071d81e37538cd246a6fe2014ec3462f090654	Application of Deep Learning Algorithm in Web Page Advertising Design Style
Although Mexican immigrants to the United States (US) have historically held health and mortality advantages over US-born groups, evolving population dynamics in Mexico paired with shifts in Mexico-US immigration patterns and policy regimes have raised new concerns about the metabolic health of recent cohorts of Mexican immigrants. Using a nationally representative sample of adults aged 20-years and older (n = 10,833) from the National Health and Nutrition Examination Study (NHANES, 1999-2016), we assess and seek to explain differences in metabolic syndrome (MetS) risk by race-ethnicity, country of origin, and duration of residence in the US and evaluate whether recent Mexican immigrants continue to exhibit a metabolic health advantage. We decompose the difference in MetS prevalence between US-born whites (45.5%) and recent Mexican immigrants (29.5%) to determine how demographic, socioeconomic, and health behavior characteristics contribute to the patterning of metabolic health. Findings reveal that recent Mexican immigrants hold a metabolic health advantage over all groups, which is accounted for by their younger age structure. Yet recent Mexican immigrants would retain a sizable age-adjusted MetS advantage if they were to achieve parity with US-born whites on education, income, and food security. To ensure that newly-arrived Mexican immigrants continue to experience historically favorable health and mortality prospects, modest policy changes could offer health-promoting protections in the form of increased economic and food security, as well as improved educational opportunities for younger immigrants.	Maria Carabello\|Julia A. Wolfson	[ { "bbox": "[57,206,806,269]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.ssmph.2021.100932	true	en	Medicine and Health Sciences	55801399dd9faf6b5c3e4804ff836347cdbe9c81afa64daf6e797b3e366e7e01	Mexican immigrant health advantage in metabolic syndrome? Examining the contributions of demographic, socioeconomic, and health behavior characteristics
	J.M. DeRouchey\|M.D. Tokach\|R.D. Goodband\|L.L. Thomas\|J.C. Woodworth\|Jordan T. Gebhardt\|S.S. Dritz	[ { "bbox": "[57,206,813,248]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.livsci.2021.104500	true	en	Medicine and Health Sciences	b65ff5e5a077a59e8f060a8f182ffede1a4156d2d021287d57246031a10751ae	Modeling standardized ileal digestible lysine requirements during gestation on gilts and sows
The Tokyo 2020 Olympic Games is expected to be among the hottest Games in modern history, increasing the chances for exertional heat stroke (EHS) incidence, especially in non-acclimatised athletes/workers/spectators. The urgent need to recognise EHS symptoms to protect all attendees' health has considerably accelerated research examining the most effective cooling strategies and the development of wearable cooling technology and real-time temperature monitoring. While these technological advances will aid the early identification of EHS cases, there are several potential ethical considerations for governing bodies and sports organisers. For example, the impact of recently developed cooling wearables on health and performance is unknown. Concerning improving athletic performance in a hot environment, there is uncertainty about this technology's availability to all athletes. Furthermore, the real potential to obtain real-time core temperature data will oblige medical teams to make crucial decisions around their athletes continuing their competitions or withdraw. Therefore, the aim of this review is (1) to summarise the practical applications of the most novel cooling strategies/technologies for both safety (of athletes, spectators and workers) and performance purposes, and (2) to inform of the opportunities offered by recent technological developments for the early recognition and diagnosis of EHS. These opportunities are presented alongside several ethical dilemmas that require sports governing bodies to react by regulating the validity of recent technologies and their availability to all.	Yannis P Pitsiladis\|Yuri Hosokawa\|Sebastien Racinais\|Borja Muniz-Pardos\|Douglas J Casa\|Konstantinos Angeloudis\|Fumihiro Yamasawa\|Wolfgang Schobersberger\|Garrett I Ash\|Andrew J Grundstein\|Fergus M Guppy\|Kumpei Tanisawa	[ { "bbox": "[75,66,181,133]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text":...	10.1136/bmjsem-2021-001041	true	en	Medicine and Health Sciences	21a69bab994be0f96616f3991b1b5412cbd44b845397ae6759df339bb0ca59c0	Ethical dilemmas and validity issues related to the use of new cooling technologies and early recognition of exertional heat illness in sport
Brazil is located between the Equator and Tropic of Capricorn, which allows diverse climates, reliefs, and habitats for arthropods, which sting represents a risk to human health and a public health issue. This manuscript updates the epidemiological data of cases of human envenoming by spiders, scorpions, and insects with medical relevance in Brazil from 2010 to 2021. Epidemiological data were taken using the Brazilian Notifiable Diseases Information System. Statistics of non-parametric data used the Kruskal-Wallis followed by the Nemenyi test. On average, more than 145,000 envenomation and 145 deaths are recorded annually, and more than 60% of deaths are caused by scorpion bites. When the number of deaths was pondered by the number of cases with each arthropod, bees kill the most. Most stings cause mild symptoms and affect men of working age. The incidence decreases during the colder months, which is better noticeable in regions with well-defined seasons. The distribution is distinct among the regions: Southeast, Northeast, and South have the highest rate of bites. The growing number of cases of envenomation reported annually is a serious public health concern, especially involving scorpions, and highlights the importance of studying arthropod venom and improving the therapies.	CASTRO, PEDRO HENRIQUE C.\|PAIVA, ANA LUIZA B.\|PEIXOTO, GUSTAVO VINÍCIUS M.\|OLIVEIRA-MENDES, BÁRBARA BRUNA R.\|CALAÇA, PAULA\|MATAVEL, ALESSANDRA	[ { "bbox": "[0,0,357,316]", "code_body": null, "code_caption": null, "image_caption": "[]", "image_footnote": "[]", "img_path": "images/1008/c65d6a3fd3883e532a0383e3879357d1591dd02b9036e722ebcdf9e0bbbd51c6.jpg", "list_items": null, "page_idx": "0", "sub_type": null, "table_bod...	10.1590/0001-3765202320220850	true	pt	Life Sciences	1bb4554f41fc6bfe1076e2cf388a59a10942598e1cd08470b4b0f3344dbaddcb	Epidemiology of arthropods envenomation in Brazil: a public health issue
	Mohamad Ahmed Selim\|Manoj Kumar Jangid	[ { "bbox": "[97,105,899,156]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3126/jnps.v40i1.28854	true	en	Medicine and Health Sciences	eb8587ab2e98c08353bf35eb0738b98150161b796e158705d742dbc5899108d3	Community-Acquired Pseudomonas Aeruginosa Wrist Joint Arthritis in a Child - A Case Report
	Jaroslav Marek\|Jiří Tuček	[ { "bbox": "[58,204,816,247]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.rinp.2022.106207	true	en	Earth and Atmospheric Sciences	cbc3fb2e1ace068a9f52aa050be70eb6ab21a91dd0aec4b05d3c84edb99a3372	Verification and estimation of uncertainties of Tobias Mayer's 18th century astronomical observations
		[ { "bbox": "[30,70,170,176]", "code_body": null, "code_caption": null, "image_caption": "[]", "image_footnote": "[]", "img_path": "images/0751/42724aa6c385a15e3c90d15b6b6f08e1a763050635858b54d22834c558dab8f9.jpg", "list_items": null, "page_idx": "0", "sub_type": null, "table_b...	10.1002/sctm.12741	true	en	Medicine and Health Sciences	4540b82cdd305a75ff8944abd84a85ff3b6ed681a2f8efbec5782c0c8dbf5711	Front Cover
	Zhifu Zhang\|Jiaxuan Wang\|Qibai Huang	[ { "bbox": "[57,206,813,271]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.rinp.2021.104408	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	661554d9fb038dab3583c44b14aa4f85c77f1644bd054e52d3a522015b374622	A novel semi-analytical methodology for predicting sound absorption of anechoic coatings with arbitrary rotary cavities dependent on temperature and frequency
	Limin Jia\|ShanShan Mo	[ { "bbox": "[60,131,243,144]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1088/1742-6596/2390/1/012064	true	en	Earth and Atmospheric Sciences	8d17afa798f27d646198808206fb0eda93fed975b773df69d7128180530e69fe	Research on the agile management system of workshop production resources
This study aimed to determine the prognostic value of a panel of SIR-biomarkers, relative to standard clinicopathological variables, to improve mRCC patient selection for cytoreductive nephrectomy (CN). A panel of preoperative SIR-biomarkers, including the albumin–globulin ratio (AGR), De Ritis ratio (DRR), and systemic immune-inflammation index (SII), was assessed in 613 patients treated with CN for mRCC. Patients were randomly divided into training and testing cohorts (65/35%). A machine learning-based variable selection approach (LASSO regression) was used for the fitting of the most informative, yet parsimonious multivariable models with respect to prognosis of cancer-specific survival (CSS). The discriminatory ability of the model was quantified using the C-index. After validation and calibration of the model, a nomogram was created, and decision curve analysis (DCA) was used to evaluate the clinical net benefit. SIR-biomarkers were selected by the machine-learning process to be of high discriminatory power during the fitting of the model. Low AGR remained significantly associated with CSS in both training (HR 1.40, 95% CI 1.07–1.82, p = 0.01) and testing (HR 1.78, 95% CI 1.26–2.51, p = 0.01) cohorts. High levels of SII (HR 1.51, 95% CI 1.10–2.08, p = 0.01) and DRR (HR 1.41, 95% CI 1.01–1.96, p = 0.04) were associated with CSS only in the testing cohort. The exclusion of the SIR-biomarkers for the prognosis of CSS did not result in a significant decrease in C-index (− 0.9%) for the training cohort, while the exclusion of SIR-biomarkers led to a reduction in C-index in the testing cohort (− 5.8%). However, SIR-biomarkers only marginally increased the discriminatory ability of the respective model in comparison to the standard model. Despite the high discriminatory ability during the fitting of the model with machine-learning approach, the panel of readily available blood-based SIR-biomarkers failed to add a clinical benefit beyond the standard model.	Ekaterina Laukhtina\|Victor M. Schuettfort\|David D’Andrea\|Benjamin Pradere\|Fahad Quhal\|Keiichiro Mori\|Reza Sari Motlagh\|Hadi Mostafaei\|Satoshi Katayama\|Nico C. Grossmann\|Pawel Rajwa\|Pierre I. Karakiewicz\|Manuela Schmidinger\|Harun Fajkovic\|Dmitry Enikeev\|Shahrokh F. Shariat	[ { "bbox": "[90,79,240,94]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text": ...	10.1007/s00345-021-03844-w	true	en	Medicine and Health Sciences	f0eac90a75b7fdce9f7a188893245dda1767e4de464350f74f887333eabd6099	Selection and evaluation of preoperative systemic inflammatory response biomarkers model prior to cytoreductive nephrectomy using a machine-learning approach
Natural products are a source of a wide range of chemical compounds, from pigments to bioactive compounds, which can be extracted and used in different applications. Due to consumer awareness, the interest in natural compounds significantly increased in the last decades, prompting the search for more efficient and environmentally friendly extraction techniques and methods. Pressurized liquids and fluids (sub and supercritical) are being explored to extract natural compounds within the green process concept. The combination of these techniques with ultrasound has emerged as an alternative to intensify the extraction process efficiently. In this context, this work presents a comprehensive review and current insights into the use of high-pressure systems, specifically supercritical fluid extraction and pressurized liquid extraction assisted by ultrasound, as emerging technologies for extracting bioactive compounds from natural products. The extraction mechanisms, applications, and the influence of operational parameters in the process are addressed, in addition to an analysis of the main challenges to be overcome for widespread application.	Arthur Luiz Baião Dias\|Ana Carolina de Aguiar\|Maurício A Rostagno	[ { "bbox": "[58,182,115,196]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.ultsonch.2021.105584	true	en	Medicine and Health Sciences/Engineering and Manufacturing Science	0fec548d10a932d4d750b2e3b087540fbbdba03c4dea0d6ffa3d8e8b54505cef	Extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: Current status and trends
BackgroundNeoplasms are a series of diseases affecting human health. Prognostic and tumor status–related markers for various tumors should be identified.MethodsBased on 19,515 samples from multiple sources, for the first time, this study provided an overview of gene S-phase kinase associated protein 2 (SKP2) in pan-cancer. Differential SKP2 expression in multiple comparison groups was identified by the Kruskal–Wallis test and Wilcoxon rank-sum test. The prognosis significance of SKP2 in individuals with neoplasm was evaluated through univariate Cox regression analysis and Kaplan-Meier curves. The area under the curve was utilized to detect the accuracy of SKP2 in predicting cancer status. Spearman’s rank correlation coefficients were calculated in all correlation analyses. Gene set enrichment analysis was used to identify essential signaling pathways of SKP2 in human neoplasms.ResultsThe study disclosed the upregulated SKP2 expression in 15 neoplasms and decreased SKP2 expression in three cancers (pu2009<u20090.05). The transcription factor Forkhead Box M1 may contribute to the increased expression levels of SKP2 in certain tumors. Over-expressed SKP2 represented a risk factor for the prognosis of most cancer patients (hazard ratiou2009>u20091, pu2009<u20090.05). SKP2 expression made it feasible to distinguish neoplasm and control tissues of 21 neoplasms (sensitivityu2009=u20090.79, specificityu2009=u20090.87, area under the curveu2009=u20090.90), implying its potential in screening a series of neoplasms. Further, the research revealed the close association of SKP2 expression with DNA methyltransferases, mismatch repair genes, microsatellite instability, tumor mutational burden, neoantigen count, and immunity.ConclusionsSKP2 plays an essential role in multiple neoplasms and may serve as a marker for treating and identifying these neoplasms.	Hua-Fu Zhou\|Tao Huang\|Guo-Sheng Li	[ { "bbox": "[97,113,223,131]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1186/s12920-023-01561-4	true	en	Medicine and Health Sciences	b1eb80811455417b6f3764b46c3cabecf35ea1a5fed646304fbc268260e56c1f	Gene S-phase kinase associated protein 2 is a novel prognostic marker in human neoplasms
		[ { "bbox": "[112,90,883,150]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1021/acsapm.1c00452.s001	true	en	Chemistry/Materials Science and Engineering	8f4ac7491412b7f24205401abb2a249d9c3932e19fcf461605bc53d7e742d9f5	Vapor-Phase-Infiltrated AlO<i><sub>x</sub></i>/PIM‑1 “Hybrid Scaffolds” as Solution-Processable\nAmine Supports for CO<sub>2</sub> Adsorption
	April, Julien\|Regan, Fiona\|Parle‐McDermott, Anne\|Hernandez, Cecilia\|Bernatchez, Louis\|Williams, Molly‐Ann\|O'Sullivan, Antóin M.	[ { "bbox": "[70,135,816,191]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1002/edn3.174	true	en	Life Sciences	23586021af8b4c0b0ee2932f0a689490276b9067020541d89d401521ab122437	Comparing CRISPR‐Cas and qPCR eDNA assays for the detection of Atlantic salmon (<i>Salmo salar</i> L.)
Background: Clinical guidelines on infection control strategies in healthcare workers (HCWs) play an important role in protecting them during the severe acute respiratory syndrome coronavirus 2 pandemic. Poorly constructed guidelines that are incomprehensive and/or ambiguous may compromise HCWs' safety. Objective: The objective of this study was to develop and validate a tool to appraise guidelines on infection control strategies in HCWs based on the guidelines published early in the coronavirus disease 2019 pandemic. Design, setting, and outcomes: A three-stage, web-based, Delphi consensus-building process among a panel of diverse HCWs and healthcare managers was performed. The tool was validated by appraising 40 international, specialty-specific, and procedure-specific guidelines along with national guidelines from countries with a wide range of gross national income. Results: Overall consensus (>75%) was reached at the end of three rounds for all six domains included in the tool. The Delphi panel recommended an ideal infection control guideline should encompass six domains: general characteristics (domain 1), engineering recommendations (domain 2), personal protective equipment (PPE) use (domain 3), and administrative aspects (domain 4-6) of infection control. The appraisal tool performed well across the six domains, and the inter-rater agreement was excellent for the 40 guidelines. All included guidelines performed relatively better in domains 1-3 than in domains 4-6, and this was more evident in guidelines originating from lower income countries. Conclusion: The guideline appraisal tool was robust and easy to use. Engineering recommendations aspects of infection control, administrative measures that promote optimal PPE use, and HCW wellbeing were generally lacking in assessed guidelines. This tool may enable health systems to adopt high-quality HCW infection control guidelines during the severe acute respiratory syndrome coronavirus 2 pandemic and may also provide a framework for future guideline development.(c) 2021 Australian College of Critical Care Nurses Ltd. Published by Elsevier Ltd. All rights reserved.	Haji, Jumana\|Kadam, Umesh\|Zubarev, Alexander\|Lim, Zheng\|Mitra, Saikat\|Rubulotta, Francesca\|Shek\|Rajamani, Arvind\|Subramaniam, Ashwin\|Luo, Jinghang\|Anstey, Chris\|Ramanathan, Kollengode\|Reddy, Mallikarjuna Ponnapa\|Svensk, Erik\|Bihari, Shailesh	[ { "bbox": "[65,196,189,211]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.aucc.2021.06.015	true	en	Medicine and Health Sciences	02ebdb5de2445391f764355fce95c4b88c7e0c68e507fef17906230ceb3e6a49	Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers
	R Nurlaily\|Samijan	[ { "bbox": "[60,131,243,144]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1088/1755-1315/724/1/012040	true	en	Life Sciences	48630313fcb5da36a698770a712c7b06a735223ab59487f2e1c1d9b8014a238d	Minimizing the impact of climate change through the determination of land and plant technology needs based on the agroecological zone on food crops in Boyolali District of Central Java, Indonesia
	Rupnik, Urban\|Alić, Alen\|Miljavec, Damijan	[ { "bbox": "[53,122,107,136]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.3390/en15186760	true	en	Materials Science and Engineering	38ed8741b4d5c6b6803792664d47b3e88a9b07d4ce50c54b436c4de3ed0d76c8	Harmonization and Validation of Jiles–Atherton Static Hysteresis Models
	Stephan P. Möller\|Pragalathan Apputhurai\|Jason A. Tye-Din\|Simon R. Knowles	[ { "bbox": "[57,206,816,250]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text"...	10.1016/j.jpsychores.2021.110711	true	en	Medicine and Health Sciences	57da27ea461b0aacafe4552570b93bf1f6f57dadceb2c62eeafff45a72eb5398	Longitudinal assessment of the common sense model before and during the COVID-19 pandemic: A large coeliac disease cohort study
	Gui Hwan Han\|Kong-Min Kim\|Lavanya Madhavaraj\|Dae-Hyuk Kim\|Ho-Dong Lim	[ { "bbox": "[124,116,176,130]", "code_body": null, "code_caption": null, "image_caption": null, "image_footnote": null, "img_path": null, "list_items": null, "page_idx": "0", "sub_type": null, "table_body": null, "table_caption": null, "table_footnote": null, "text...	10.3390/su12187587	true	en	Chemistry/Engineering and Manufacturing Science	a9f1965e93d987951bf057105862afabb855654135499c1eaea78f20e22bb5fe	Influence of Sargassum horneri Mitigating Odorous Gas Emissions from Swine Manure Storage Facilities