 flies.** (A) Relative heart *dSir0* mRNA expression level. (B) Heart dSIR0 level. (C) Heart NAD^+^ levels. (D) Relative heart *PGC-0α* mRNA expression level. (E) Heart diastolic diameter. (F) Heart systolic diameter. (G) Fractional shortening. (H) Arrhythmia index. (I) 