0% (i.e. dropping SNPs with allele frequency ≤0.00 or ≥0.00) and with MAF > 00% (i.e. dropping SNPs with allele frequency ≤0.00 or ≥0.00), respectively, from the 0,000,000 SNPs that survived quality control. Next, we used r0 > 0.0 and 0000 kb as the clumping parameters and the 0000 Genomes phase 0 version 0 European reference panel to estimate LD among SNPs, eventually leaving a set of 000,000 approximately independent lead-SNPs with MAF > 0% and 000,000 SNPs with MAF > 00% ready for profile scoring. The resulting scores are called 