xe0x00x00C(xe0x00x00O)xe0x00x00CHRXxe0x00x00, xe0x00x00CHRXxe0x00x00C(xe0x00x00O), and cycloalkylene; each RX is independently selected from the group consisting of hydrogen, hydroxy, alkyl, haloalkyl, aminoalkyl, guanidinoalkyl, alkoxy, amino, alkylamino, dialkylamino, cycloamino, alkylcarbonylamino, guanidino, carboxy, alkoxycarbonyl, and tetrazole; each RY is independently selected from the group consisting of hydrogen, alkyl, haloalkyl, carboxy, and alkoxycarbonyl; each R0 is independently selected from the group consisting of hydrogen and lower alkyl; R0 is selected from the group consisting of hydrogen, halo and hydroxy; R0 is selected from the group consisting of hydrogen, halo, alkyl, haloalkyl, alkoxy, amino, alkylcarbonylamino, alkylsulfonylamino, benzenesulfonylamino, toluenesulfonylamino, carboxy, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, cycloaminocarbonyl, and alkoxycarbonyl; R0 is selected from the group consisting of hydrogen, halo, and hydroxy; R0, R0, R00, R00, R00, R00, R00