*[@b0-copd-0-000]                                           *Streptococcus pneumonia*[@b00-copd-0-000],[@b00-copd-0-000]   *Streptococcus pneumonia*[@b00-copd-0-000],[@b00-copd-0-000]                    *Streptococcus pneumonia*[@b00-copd-0-000]