olon cancer cell lines DLD-0, Lovo, HCT-000, Colo000, SW000, Colo000, and HT-00 were treated with 000 nM of 0-AC every 00 hours for 0 consecutive days and harvested at 00 days after the beginning of treatment. RNA was isolated and made into cDNA. qRT-PCR was performed on *B0M* (Fig 0A), *CALR* (Fig 0B), *CD00* (Fig 0C), *PSMB0* (Fig 0D), *PSMB0* (Fig 0E), *TAP0* (Fig 0F), and *TAPBP* (Fig 0G). Data is presented as log~0~ fold change over mock (untreated cells). Significance is indicated on graphs (n.s. = not significant, \* = p \<0.00, \*\* = p \< 0.000, \*\*\* = p \< 0.000).](pone.0000000.g000){#pone.0000000.g000}  