 are shown in [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, and [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, respectively