s. *Ctrl_HE* healthy control cells, *Ctrl_EMS* EMS control cells, *EMS_Cal 000* EMS cells treated with 000 μg/ml of calystegines, *EMS_Cal 000* EMS cells treated with 000 μg/ml of calystegines. Asterisk (\*) refers to the comparison of EMS treated and untreated groups to untreated healthy cells. Hashtag (\#) refers to the comparison of EMS treated groups to EMS untreated cells. *\**^*/\#*^*p* \< 0.00, *\*\**^*/\#\#*^*p* \< 0.00, *\*\*\**^*/\#\#\#*^*p* \< 0.000  Effect of calystegines on 