e {#embj0000000000-sec-0000} -----------------------------  As reported previously (Merrill *et al*, [0000](#embj0000000000-bib-0000){ref-type="ref"}; Niemann *et al*, [0000](#embj0000000000-bib-0000){ref-type="ref"}; Petersson *et al*, [0000](#embj0000000000-bib-0000){ref-type="ref"}, [0000](#embj0000000000-bib-0000){ref-type="ref"}), in 