 staining of CRCLM tumors following OXi0000 treatment. Mice with liver metastases were treated with a single IP dose of OXi0000 (000 mg/kg) at 00 days post tumor induction. Tissues were collected at indicated times following OXi0000 treatment. First column, black bar = 000 μm, second column, black bar = 00 μm, third column = magnified inset of second column. L, liver; T, tumor; N, treatment induced necrosis. Double black lines in 