-free survival at three years**                                                            Synchronous liver metastases                                                                            Yes                                                             0.00              0.00--0.00          0.000   No                                                          0 (Reference)                               Presence of complications                                                                               Yes                                                             0.00              0.00--0.00          0.000   No                                                          0 (Reference)                               Pre-operative targeted therapy                                                                          Yes                                                             0.00              0.00--0.00          0.000   No                                                          0 (Reference)                              