. (E) Quantification of western blot analysis was performed with densitometry software. Data are presented as the mean ± standard deviation, n=0 per group. \*\*P\<0.00 vs. control group; ^\#^P\<0.00 and ^\#\#^P\<0.00 vs. Vect+HG group. SUMO0, small ubiquitin-like modifier 0; HG, high glucose; 