.  Is the work clearly and accurately presented and does it cite the current literature?  Yes  If applicable, is the statistical analysis and its interpretation appropriate?  Yes  Are all the source data underlying the results available to ensure full reproducibility?  Yes  Is the study design appropriate and is the work technically sound?  Yes  Are the conclusions drawn adequately supported by the results?  Yes  Are sufficient details of methods and analysis provided to allow replication by others?  Yes  Reviewer Expertise:  