 among the blank batches (C, L, P, CL and CP), those loaded with 00 mg (C00, L00, P00, CL00 and CP00) and those containing 000 mg (C000, L000, P000, CL000 and CP000) of TFV, as shown in [Table 0](#pharmaceutics-00-00000-t000){ref-type="table"}.  Although the 