 mutant truly aphenotypic? What about LR symmetry?  0\) Based on the ability of 00 pg of RNA encoding Vg0-NC not to rescue Mvg0 mutant phenotype the authors conclude that endogenous cleavage is required for Vg0 function appears too strong. Higher RNA doses should be tested.  0\) Immunoblot experiments presented in [Figure 0E](#fig0){ref-type="fig"} should be quantified; there are no loading controls in these experiments.  0\) Experiments testing the intracellular localization of Vg0(Cyc;Sqt)-sfGFP would be more compelling if RNAs encoding these molecules would be injected with RNA encoding membraneRFP.  0\) What RNA doses were injected in embryos shown in [Figure 0](#fig0){ref-type="fig"}?  0\) Experiments presented in [Figure 0](#fig0){ref-type="fig"}, would be more informative if 