0 mg/kg group was significantly increased (p \< 0.00; p \< 0.00; F = 00.00; df total = 00) compared to their body weights on day 0; CCRB 00 mg/kg group was significantly increased (p \< 0.00; p \< 0.000; F = 00.00; df total = 00) compared to their body weights on day 0; CCRB 000 mg/kg group was significantly increased (p \< 0.00; 