    F/00            C                        0                     +/+/−/−/−           00              0         Severe    0       F/00            C                        0                     +/+/+/−/−           0               0         Severe    0       F/00            RR                       0                     −/−/−/−/−           0               0         Severe    0       F/00            RR                       00                    −/−/−/−/−           