   00.00   Prim^−^/Met^+^   00               00    0.00                                      0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                  0.00    0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                    Prim^+^/Met^−^   000              00    0.00                                      0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                  0.00    0.00 to 0.00                               \<0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                  Prim^−^/Met^−^   000              00    0.00                                      0.00 to 0.00                               \<0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                0.00    0.00 to 0.00                               \<0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                  HR               Prim^+^/Met^+^   000   00                                        0.0 [^d^](#tfn_000){ref-type="table-fn"}   ---                                             0.000 [\*](#tfn_000){ref-type="table-fn"}    00.00   0.0 [^d^](#tfn_000){ref-type="table-fn"}   ---                                             0.000 [\*](#tfn_000){ref-type="table-fn"}   00.00   Prim^−^/Met^+^   00               00    0.00                                      0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                  0.00    0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                    Prim^+^/Met^−^   000              00    0.00                                      0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                  0.00    0.00 to 0.00                               0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                    Prim^−^/Met^−^   000              00    0.00                                      0.00 to 0.00                               \<0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                0.00    0.00 to 0.00                               \<0.000 [\*\*](#tfn_000){ref-type="table-fn"}                                                 Abbreviations: ER, estrogen receptor; PR, progesterone receptor; H