 Our tests on several gene expression profiling datasets of cancer patients consistently indicate that the RM-GNMF-based method achieves significant improvements in comparison with the NMF-based method, the $l_{0,0}$-NMF-based method, the LNMF-based method, and the GNMF-based method, in terms of cancer prediction accuracy.  As shown in [Figure 0](#molecules-00-00000-f000){ref-type="fig"}, the 