 the covariant changes in the FA value in AD patients compared to HCs ([Fig. 0](#pone.0000000.g000){ref-type="fig"} (A0, B0, C0), [Fig. 0](#pone.0000000.g000){ref-type="fig"}(A0, B0), [Fig. 0](#pone.0000000.g000){ref-type="fig"}(A0, B0)) 