   OR[^a^](#t000fn000){ref-type="table-fn"}   00% CI    *p*-value   --------------------------------------------------------------- -------------------------- ------ ------------------------------------------ --------- -----------   **Non-advanced adenoma**                                        Average-risk individuals   000    0 [^b^](#t000fn000){ref-type="table-fn"}                One FDR with CRC diagnosed at ≥ 00 y                            000                        0.00   0.00 to 0.00                               0.00         One FDR with CRC diagnosed at \< 00 y                           000                        0.00   0.00 to 0.00                               0.00         Two FDR with CRC diagnosed at any age                           00                         0.00   0.00 to 0.00                               0.00         **Advanced 