0.\ The colour bar represents Z-score. The middle panel displays their corresponding receiver operating characteristic (ROC) curves, and the right panel displays a boxplot of the between-group differences in ICA weights.](pone.0000000.g000){#pone.0000000.g000}  ![IC spatial maps displaying the covariant FA changes in white matter in AD patients compared to HCs for ICs 0 and 0.\ The colour bar represents Z-score. The middle panel displays their corresponding receiver operating characteristic (ROC) curves, and the right panel displays a boxplot of the between-group differences in ICA weights.](pone.0000000.g000){#pone.0000000.g000}  ![IC spatial maps displaying the covariant FA changes in white matter in AD patients compared to HCs for ICs 0 and 0.\ The colour bar represents Z-score. The middle panel displays their corresponding receiver operating characteristic (ROC) curve, and the right panel displays a boxplot of the between-group differences in ICA weights.](pone.0000000.g000){#pone.0000000.g000}  