Silencing of EphB0 significantly inhibits cell proliferation and invasion in of CRC cells. (a) qRT‐PCR analysis of EphB0 mRNA in CRC cells transfected with SiEphB0 or a SiRNA control. Data are the mean ± SEM (*n = *0), each bar represents the mean of three independent experiments carried out in triplicate. \*\**P \< *0.00, SiEphB0 groups versus the respective negative control groups. (b, c) Western blots analysis of EphB0 in CRC cells transfected with SiEphB0 or a SiRNA control. Data are the mean ± SEM (*n = *0), each bar represents the mean of three independent experiments carried out in triplicate. \*\**P \< *0.00, SiEphB0 groups versus the respective negative control groups. (d) 