* (*n* = 00). Data are represented as mean +/- SD with ns (not significant) and \* *p* \< 0.00, \*\* *p* \< 0.00, \*\*\* *p* \< 0.000, \*\*\*\* *p* \< 0.0000.  (TIF)  ######   Click here for additional data file.  ###### CO