 tumor cells day 0                                                                          ↑ survival                                                                                                                                                                                                                                \[[@B00]\]                                                                                                                                                                                                                                                     0-00                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                0.0, 0