. Data are presented as mean ± SEM. \* *p* \< 0.00 and \*\* *p* \< 0.00. Scale bar represents 000 μm. CONT: non-treated controls; FLU: flupirtine; LINO: linopirdine; XE: XE000; ALP: alkaline phosphatase; OSC: osteocalcin; OD: optical density.](ijms-00-00000-g000){#ijms-00-00000-f000}  ![Suppressive effect of 