 (see [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}, and [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}).](pcbi.0000000.g000){#pcbi-0000000-g000}  T