I can't say how much participation Heavenly Father has in our imperfections and handicaps, I truly can't. Personally, I don't believe He creates them, but I do believe He allows the natural anomalies that come with mortality. I also agree with what Logan said: "In the eternal perspective, handicaps and imperfections might not turn out to be the disadvantages we thought they were." We naturally tend to think with mortal perspectives, and that casts shadows on the way we see our challenges.  I'll say it one more time: I was just posing a question. I thought it, so I asked it. But I certainly don't agree that synthetic genetic engineering or man-made DNA-