 Females of many animal species emit chemical signals that attract and arouse males for mating. For example, the major aphrodisiac pheromone of Drosophila melanogaster females, 0,00-heptacosadiene (0,00-HD, is a potent inducer of male-specific courtship and copulatory behaviors. Here, we demonstrate that a set of gustatory sensory neurons on the male foreleg, defined by expression of the ppk00 marker, respond to 0,00-HD. Activity of these neurons is required for males to robustly court females or to court males perfumed with 0,00-HD. Artificial activation of these ppk00