, and cycloalkylene; each RX is independently selected from the group consisting of hydrogen, hydroxy, alkyl, haloalkyl, aminoalkyl, guanidinoalkyl, alkoxy, amino, alkylamino, dialkylamino, cycloamino, alkylcarbonylamino, guanidino, carboxy, alkoxycarbonyl, and tetrazole; each RY is independently selected from the group consisting of hydrogen, alkyl, haloalkyl, carboxy, and alkoxycarbonyl; each R0 is independently selected from the group consisting of hydrogen and lower alkyl; R0 is selected from the group consisting of hydrogen, halo, and hydroxy; R0 is selected from the group consisting of 