00000)                                                                 X                               **+/+**             SPU_000000                                                                                                                                                                                                                                                                                                                                                                                                             **00**                 00000         KOG0000    Cytoskeleton                                                    Coiled-coil                                                                                                                Coiled-coil 000                                                                                         X                               +/?                 SPU_000000                                                                                                                                                                                                                                                                                                                                                                                                             **00**                 000000        KOG0000    Signal transduction mechanisms                                  Frizzled, 