ression.  ![](pone.0000000.t000){#pone.0000000.t000g}                                           Patients (n)   HR (00% CI)         p-value   -------------------------------------- -------------- ------------------- -----------   **Age (continuous)**                                                                                                \-             0.00 (0.00--0.00)   0.00   **Gender**                                                                   Male                                   00             0.00                   Female                                 00             0.00 (0.00--0.00)   0.00   **MMP-0 intensity first 0.0 months**                                         Low                                    00             0.00                   High                                   00             0.00 (0.00--0.00)   0.00   **MMP-0 intensity after 0.0 months**                                         Low                                    00             0.00                   High                                   00             0.00 (0.00--0.00)   **0.000**  