R status subtypes  **A.** OS associated with various ER statuses in primary breast cancer (Prim) or metastatic sites (Met). **B.** Post-recurrent survival associated with various ER statuses in primary breast cancer (Prim) and metastatic sites (Met).  ![](oncotarget-00-00000-g000a)  ![](oncotarget-00-00000-g000b)  A