 the three active residues (Asp000, Glu000, and Asp000), twelve functional residues (Glu000, Tyr000, His000, Thr000, Arg000, Trp000, Asp000, Arg000, Tyr000, His000, Asn000, Asn000), and eighteen water molecules (W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000, W000)