^](#t000fn000){ref-type="table-fn"}   Average-risk individuals   000   000   000     0.00                                       0.00 to 0.00   \<0.000   One FDR with CRC diagnosed at ≥00 y                             000                        000   00    0.00    0.00 to 0.00                               \<0.000           One FDR with CRC diagnosed at \<00 y                            00                         00    00    0.00    0.00 to 0.00                               \<0.000           Two FDR with CRC diagnosed at any age                           00                         00    00    0.00    0.00 to 0.00                               0.000            CI = confidence interval; FDR = first-degree relatives; CRC = colorectal cancer; 