00} -----------------  Further information on research design is available in the [Nature Research Reporting Summary](#MOESM0){ref-type="media"} linked to this article.  Supplementary information =========================   {#Sec00}  Supplementary Information Peer Review File Reporting Summary  **Peer review information** *Nature Communications* thanks the anonymous reviewers for their contribution to the peer review of this work. Peer reviewer reports are available.  **Publisher's note** Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.  Supplementary information =========================  **Supplementary information** is available for this paper at 00.0000/s00000-000-00000-0.  This work was supported by the UK Medical Research Council (MC_UU_00000/0