 used for measurement of cell viability. CI was calculated using Additive model. It should be noted that the sequencing method used (Sanger sequencing and Single Strand Conformation Analysis) cannot distinguish between homozygous and hemizygous mutations. Also, 'het.\' refers to that both wt p00 and mut p00 are found in the sample. This can either be due to heterozygosity or to a presence of cells with different p00 status, which is not common in cancer cell lines but may occur in primary cancer cells  