 To some extent, the same argument also holds for the P0 monomer reconstruction: doing purely focussed classifications (without re-alignments) of symmetry-expanded images should also improve this part of the map. The only caveat (and cause for lower resolution) in this case would be different orientations of the P0 monomer relative to the capsid. However, even this may be captured better by focussed classifications without alignment than by the currently used focussed refinements.  