 show a diversity of time scales. Each data point shown is the median of the SDR-transformed (see Equation 0) differential expression levels of the genes within the indicated cluster, at the indicated time after stimulation. Cluster C00 shows sustained activation under this stimulus, as opposed to the case of stimulation with LPS (see [Figure S0](#pcbi.0000000.s000){ref-type="supplementary-material"}).  (0.00 MB TIF)  ######   Click here for additional data file.  ######   Cluster-median differential expression profiles in wild-type macrophages stimulated with 