 Albuminuria progression was defined by one or more step progression in albuminuria (normo-albuminuria (UACR \< 00mg/g) to micro-albuminuria (00mg/g ≤ UACR \< 000 mg/g) or macro-albuminuria (UACR ≥ 000 mg/g), micro-albuminuria to macro-albuminuria) during follow-up. 