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PMCE: efficient inference of expressive models of cancer evolution with high prognostic power
bioinformatics
Convergent evolution of primate testis transcriptomes reflects mating strategy
evolutionary biology
A max-margin model for predicting residue-base contacts in protein-RNA interactions
bioinformatics
Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system
synthetic biology
Association of NQO1 C609T (Pro187Ser) with risk of Oral Submucous Fibrosis in Eastern Indian population
genetics
Fast gene set enrichment analysis
bioinformatics
Immunoecology of species with alternative reproductive tactics and strategies
evolutionary biology
Frameshifts and wild-type protein sequences are always highly similar because the genetic code and genomes were optimized for frameshift tolerance
genetics
Estimating the timing of multiple admixture events using 3-locus Linkage Disequilibrium
bioinformatics
Revisiting the effect of red on competition in humans
evolutionary biology
Resolving the Functional Significance of BRCA1 RING Domain Missense Substitutions
genetics
Sustained software development, not number of citations or journal choice, is indicative of accurate bioinformatic software
bioinformatics
Correcting Chimeric Crosstalk in Single Cell RNA-seq Experiments
bioinformatics
The Arabidopsis Framework Model version 2 predicts the organism-level effects of circadian clock gene mis-regulation
plant biology
Aperiodic neural activity is a better predictor of schizophrenia than neural oscillations
neuroscience
Population Temporal Structure Supplements The Rate Code During Sensorimotor Transformations
neuroscience
Sexual dimorphism and plasticity in wing shape in three Diptera
zoology
Laser-free super-resolution microscopy
biophysics
The Effects of Central Nervous System Stimulants on Drosophila melanogaster Reproduction
developmental biology
Proteins with prion-like domains can form viscoelastic condensates that enable membrane remodeling and endocytosis
cell biology
Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans
neuroscience
Distinct C4 Sub-Types and C3 Bundle Sheath Isolation In The Paniceae Grasses
plant biology
The effects of an 8-week mindful eating intervention on anticipatory reward responses in striatum and midbrain
neuroscience
Bromodomains regulate dynamic targeting of the PBAF chromatin remodeling complex to chromatin hubs
cell biology
cytoNet: Spatiotemporal Network Analysis of Cell Communities
bioengineering
Plant genetic effects on microbial hubs impact fitness across field trials
plant biology
MARS-Net: Deep learning-based segmentation pipeline for profiling cellular morphodynamics from multiple types of live cell microscopy
bioinformatics
Histone deacetylase inhibition reduces deleterious cytokine release induced by ingenol stimulation
microbiology
Plasma amyloid 尾 levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants
genetics
Measuring nonapoptotic caspase activity with a transgenic reporter in mice
neuroscience
Improved management facilitates return of an iconic fish species
ecology
Early urinary candidate biomarkers and clinical outcomes of intervention in a rat model of experimental autoimmune encephalomyelitis
biochemistry
Majority of choice-related variability in perceptual decisions is present in early sensory cortex
neuroscience
Removing unwanted variation between samples in Hi-C experiments
genomics
A bacterial GW-effector directly targets Arabidopsis Argonaute 1 to suppress PAMP-triggered immunity and cause disease
plant biology
Differential and defective expression of Koala Retrovirus indicate complexity of host and virus evolution
microbiology
Experimental evidence of non-classical brain functions
bioinformatics
A GenoChemetic strategy for derivatization of the violacein natural product scaffold
synthetic biology
Proof of concept continuous event logging in living cells
synthetic biology
Modeling Dynamic Transcriptional Circuits with CRISPRi
synthetic biology
Scanning along a compressed timeline of the future
animal behavior and cognition
Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer
cancer biology
System drift and speciation
evolutionary biology
The effectiveness of glass beads for plating cell cultures
biophysics
Iron oxidation by a fused cytochrome-porin common to diverse iron-oxidizing bacteria
microbiology
Novel Integrative Modeling of Molecules and Morphology Pinpoints Caninae Evolution across Timescales
evolutionary biology
Dynamic Flux Balance Analysis Models in SBML
bioinformatics
Seidr: Efficient Calculation of Robust Ensemble Gene Networks
bioinformatics
High-throughput microcolony growth analysis from suboptimal low-magnification micrographs
bioinformatics
Visual and auditory brain areas share a representational structure that supports emotion perception
neuroscience
Bayesian model comparison for rare variant association studies
genetics
Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration
immunology
Genie: An interactive real-time simulation for teaching genetic drift
scientific communication and education
The effect of mutational robustness on the evolvability of multicellular organisms
evolutionary biology
The importance of semantic network brain regions in integrating prior knowledge with an ongoing dialogue
neuroscience
Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis
genomics
Effects of adaptive harvesting on fishing down processes and resilience changes in predator-prey systems
ecology
Does deterministic coexistence theory matter in a finite world?
ecology
Splicing motifs are organized within global structural scaffold of a pre-mRNA
biochemistry
Manipulation of the unfolded protein response: a pharmacological strategy against coronavirus infection
microbiology
Dissecting indirect genetic effects from peers in laboratory mice
genetics
Spatial distribution of private gene mutations in clear cell renal cell carcinoma
cancer biology
DsbA is a redox-switchable mechanical chaperone
biophysics
A constraints-based theory of senescence: imbalance of epigenetic and non-epigenetic information in histone crosstalk
developmental biology
Cargo-Loading of Misfolded Proteins into Extracellular Vesicles: The CSP伪-EV Export Pathway
neuroscience
Structurally Constrained Effective Brain Connectivity
neuroscience
Characterization of Animal Movement Patterns using Information Theory: a Primer
ecology
Sperm morphology differences associated with pig fertility
developmental biology
Direct programming of human mammary self-organised organoids by miR-106a-3p
cell biology
Polymer brush bilayers at thermal equilibrium: A density functional theory approach
biophysics
Empirical single-cell tracking and cell-fate simulation reveal dual roles of p53 in tumor suppression
cell biology
Identification and design of vinyl sulfone inhibitors against Cryptopain1-a cysteine protease from cryptosporidiosis-causing Cryptosporidium parvum
bioinformatics
Spatial RNA sequencing identifies robust markers of vulnerable and resistant human midbrain dopamine neurons and their expression in Parkinson's Disease
neuroscience
Dissociating Language and Thought in Human Reasoning
neuroscience
Broad geographic sampling reveals predictable, pervasive, and strong seasonal adaptation in Drosophila
evolutionary biology
3D Reconstruction of Bird Flight Using a Single Video Camera
animal behavior and cognition
The interspecific fungal hybrid Verticillium longisporum displays sub-genome-specific gene expression
microbiology
Ecological Network assembly: how the regional meta web influence local food webs
ecology
Network Reconstruction from Perturbation Time Course Data
systems biology
Rapid adaptation of endocytosis, exocytosis and eisosomes after an acute increase in membrane tension in yeast cells
cell biology
Evolutionary forecasting of phenotypic and genetic outcomes of experimental evolution in Pseudomonas protegens
evolutionary biology
KChIP4a selectively controls mesolimbic dopamine neuron inhibitory integration and learning from negative prediction errors
neuroscience
A pragmatic approach to make theoretical syntheses in ecology
ecology
Microbial adaptation to venom is common in snakes and spiders
microbiology
The Goldilocks Effect: Female geladas in mid-sized groups have higher fitness
evolutionary biology
Joint inference of species histories and gene flow
evolutionary biology
5' Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing
molecular biology
Structure-aware M. tuberculosis functional annotation uncloaks resistance, metabolic, and virulence genes
genomics
Distracting Linguistic Information Impairs Neural Tracking of Attended Speech
neuroscience
Extracellular histones, a new class of inhibitory molecules of CNS axonal regeneration
neuroscience
Dispensing a synthetic green leaf volatile to two plant species in a common garden differentially alters physiological responses and herbivory
ecology
The taxonomic and functional biogeographies of phytoplankton and zooplankton communities across boreal lakes
ecology
Predicting subclinical psychotic-like experiences on a continuum using machine learning
neuroscience
Individuals with ventromedial frontal damage have more unstable but still fundamentally transitive preferences
neuroscience
De Novo Mutational Signature Discovery in Tumor Genomes using SparseSignatures
bioinformatics
GranatumX: A community engaging, modularized and flexible software environment for single-cell analysis
bioinformatics
High-quality SNPs from genic regions highlight introgression patterns among European white oaks (Quercus petraea and Q. robur).
evolutionary biology
Eye movements during text reading align with the rate of speech production
neuroscience
Basal ganglia and cortical control of thalamic rebound spikes
neuroscience
Reduction in CD11c+ microglia correlates with clinical progression in chronic experimental autoimmune demyelination
neuroscience