question
stringclasses 12
values | choices
sequence | answer
class label 3
classes |
|---|---|---|
Which of the following is not a chromosome instability syndrome? | [
"Klinefelter syndrome",
"Ataxia telangiectasia",
"Fanconi anaemia",
"Bloom syndrome"
] | 0A
|
It is currently estimated that there are ______ human protein-coding genes although this estimate may be reduced over time. | [
"10,000–15,000",
"19,000–20,000",
"29,000–30,000",
"100,000"
] | 1B
|
Which of the following is not a familial cancer syndrome | [
"Familial adenomatous polyposis",
"Li-Fraumeni syndrome",
"Von Hippel-Lindau syndrome",
"Waardenburg syndrome"
] | 3D
|
Which of the following is not a tumour suppressor gene? | [
"APC",
"NF1",
"RB1",
"RET"
] | 3D
|
Which of the following findings on prenatal ultrasound examination would not raise suspicion of a chromosome abnormality? | [
"Duodenal atresia",
"Holoprosencephaly",
"Hydrops fetalis",
"Monozygotic twins"
] | 3D
|
Which of the following disorders is not suitable for population carrier screening? | [
"Cystic fibrosis",
"Oculocutaneous albinism",
"Sickle cell disease",
"Tay-Sachs disease"
] | 1B
|
Which of the following disorders does not show X-linked inheritance? | [
"Duchenne muscular dystrophy",
"Tay-Sachs disease",
"Haemophilia A",
"Haemophilia B"
] | 1B
|
Which of the following karyotypes is not compatible with survival to birth? | [
"47,XY,+13",
"47,XX,+18",
"47,XY,+21",
"45,Y"
] | 3D
|
Which component of transcribed RNA in eukaryotes is present in the initial transcript but is removed before translation occurs? | [
"Intron",
"3’ Poly A tail",
"Ribosome binding site",
"5’ cap"
] | 0A
|
Which of the following is not a recognized complication of cystic fibrosis? | [
"Cancer of the oesophagus",
"Congenital absence of the vas deferens",
"Diabetes mellitus",
"Liver cirrhosis"
] | 0A
|
Which of the following diagnostic techniques is of no value for the diagnosis of neural tube defects? | [
"Amniocentesis",
"Chorion villus sampling (CVS)",
"Maternal serum screening",
"Ultrasonography"
] | 1B
|
Which of the following conditions is not caused by a mutation in FGFR3? | [
"Achondroplasia",
"Crouzon syndrome",
"Thanatophoric dysplasia",
"Waardenburg syndrome"
] | 3D
|