jeffreygwang/testdata · Datasets at Hugging Face

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44002, 2055, 3218, 218, 34446, 42335, 5444, 4746, 8509, 23826, 765, 100, 14016, 11473, 3917, 48604, 103, 45683, 6088, 6686, 5832, 12335, 11016, 231, 24086, 26581, 242, 38563, 3917, 24545, 120, 17576, 26487, 104, 48889, 6957, 18757, 19067, 6418, 4746, 15962, 14321, 6686, 34179, 20557, 215, 6449, 20025, 13639, 6344, 5151, 15625, 4340, 187, 187, 15962, 29852, 105, 42335, 35300, 41492, 13610, 1348, 28779, 25276, 3917, 16677, 44360, 15899, 120, 6957, 38591, 15625, 4340, 7111, 226, 46356, 18751, 232, 37769, 103, 29741, 4746, 41162, 6449, 22, 20691, 3917, 36114, 6765, 100, 15899, 120, 5444, 21700, 111, 24168, 5891, 15962, 29852, 105, 42335 ]	his wicket-taking spells will be desperate to regain that momentum before the tour of Australia and could have a say in the third T20. 3. Dinesh Karthik - Batsman, India Dinesh Karthik is always comfortable playing in Chennai before his home crowd. And with a possible captaincy role in the third T20, Karthik will be keen to have some kind of an impact in the match. He is also the preferred wicket-keeper over Rishabh Pant and could get you a lot of points through his dismissals. 4. Carlos Brathwaite - Allrounder, West Indies West Indies has been completely outclassed in the last two matches and never looked like they were going to trouble the hosts. While many of the players looked tired, captain Brathwaite was the only player capable of creating something in the match. Brathwaite has been active and has shown glimpses of what he's capable of in his bowling as well as batting. With India already clinching the series, West Indies will be playing with nothing to lose and could hope for a better display in Chennai. 5. Oshane Thomas - Bowler, India With the likes of Rohit Sharma tearing through the opposition bowling attack, West Indies' bowlers have cut a disappointing figure so far in the series. But if there is anyone who could look to have an impact, it is Oshane Thomas. He was impressive in his spell in the first T20 and was the pick among the bowlers in the second T20 as well. Pick him and you could get some unexpected points should West Indies do well in the third T20 in Chennai.「大阪市を解体し、5つの特別区を設置する」ことをめぐり、5月17日に住民投票が予定されています。二期目の世田谷区長選挙を終えた私に対しても、この「大阪都構想・住民投票」をめぐり、関西のメディアからいくつか取材が重なりました。大阪都構想が、東京都と特別区の関係をモデルとしてつくられたと言われている以上は、都内最大の特別区である世田谷区を預かる立場から、特別区制度の置かれている現状について、しっかり伝えていく必要があると思っています。関東にいると、大阪都構想の詳細な部分はあまり伝わってきません。大阪都構想には変遷があり、現在の焦点となっている住民投票は、冒頭に書いたように大阪府（880万人）の中で、大阪市（270万人）のみを対象として、「政令指定都市である大阪市から５つの特別区」に移行することを問うものです。東京の特別区（907万人）は、東京都（1335万人）の約７割をしめているのに対して、大阪市の人口規模は、大阪府全体の約３割という点にも留意したいと思います。東京都は、戦時下の1943年（昭和18年）に、東京府と東京市を廃止して出来ました。東京市はなくなり、特別区が生まれてから70数年になります。区部は都に対して、粘り強く自治権拡充の運動を重ねてきました。1952年（昭和27年）には区は都の内部団体とされ、区長公選も廃止されています。区長公選を再実施するまでには、1975年（昭和50年）まで待たなければなりませんでした。特別区の自治は、長い運動の歴史によってつくりあげられ、まだ途上にあります。世田谷区は人口88万人と、7つの県（佐賀・島根・鳥取・徳島・高知・福井・山梨）を上まわる人口規模を持っていますが、首長の権限は一般の市町村長以下と聞くと、まさかと思う人も多いかもしれません。まず、税収が限られています。法人住民税、固定資産税（個人・法人）等は、都が徴収します。その55％が区に配分される「財政調整制度」で運営されています。（今回、大阪で5つの特別区をつくった場合には、配分率を77％にするとしています）財源を握っている都の立場は強くなり、配分を受ける区は「さじ加減」に財政上の大きな影響を受けます。今年、30年がかりの再開発が完成して、二子玉川に楽天本社が移転してきますが、都が法人住民税を受け、区には直接の税収はありません。間接的には、住民増で税収があがる等のメリットと、ただでさえ足りない保育需要が上昇する等の仕事を抱えることになります。一方で地方分権の流れで、都市計画決定権限が市町村に移行しましたが、「特別区」だけはまちづくりに重要な「用途地域」等を決める権限が除外されています。例えば、文化・芸術のインフラとして、ライブハウスや小劇場がつらなるまちづくりを誘導しようとしても、「用途地域」の変更なしには進められないのが現状です。ソウルでは、テハンノ（大学路）には小劇場が密集していますが、小劇場を持つビルオーナーに対して、固定資産税の減免を行なっています。世田谷区には、その権限はなく、固定資産税の減免という切り札を区の政策で使うことは出来ません。世田谷区独自の取り組みとして、出産直後の母子をケアする産後ケアセンター（桜新町）があります。全国的な反響を呼び、国の成長戦略のモデル事業とまで紹介されながら、区内で第２、第３の設置をすることが出来ません。これも、建築基準法で用途地域が制限されていることが、大きな理由です。区民の需要が高く、内外の評判が良くても、桜新町が準工業地域だったことで例外的に立地可能になったことを知る人は多くありません。人口88万都市に、まちづくりの骨格となる用途地域等の決定権限がないことは、大きな制約を生んでいます。大阪市には現在24カ所の行政区があります。住民投票では、これを5つの特別区に統合し大阪市
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724, 3629, 342, 370, 58, 5, 347, 470, 15 ]	sim$0.69$M_{\odot}$, and decreases to $\sim$0.63$M_{\odot}$ for $Y$=0.286. The average mass along the synthetic HB is equal to 0.66$M_{\odot}$, with a 1$\sigma$ dispersion of 0.017$M_{\odot}$. The exact values of these two quantities depend on the assumed distribution of initial $Y$, but obviously the mean mass cannot be outside the range 0.63-0.69$M_{\odot}$. A general trend of increasing $Y$ with decreasing colour is also fully consistent with the observed trend of increasing Na towards bluer colours along the cluster HB [see @gratton]. We could have tried to enforce [a priori]{} the constraint of perfect statistical agreement between the theoretical and observed star counts. However, a perfect fit rests on the precise knowledge of the statistical distribution of $\Delta M_{\rm RGB}$ and the initial $Y$ among the cluster stars. Due to the current lack of firm theoretical and empirical guidance, this distribution may be extremely complicated and/or discontinuous. The constraints imposed on the matching synthetic HB are however sufficient to put strong constraints on $\Delta M_{\rm RGB}$ –the main parameter discussed in this work– and the range of initial $Y$, which determine the region of the CMD covered by the observed HB. In fact, just the observed shape of the HB allows a good determination of both $\Delta M_{\rm RGB}$ and the $Y$ range, when $E(B-V)$, age and initial chemical composition are fixed, as can already be inferred from Fig. \[HBtracks\]. More in detail, Fig. \[HBvariations\] shows how changing these two parameters affects the shape and location of the synthetic HB. Variations of $\Delta M_{\rm RGB}$ around the reference value –keeping the reference $Y$ distribution fixed– move the location of the synthetic HB along the direction from the top-right corner of the CMD to the bottom-left one. At the same time the HB gets compressed when $\Delta M_{\rm RGB}$ is reduced (shorter loops in the CMD of the HB tracks of larger mass) and stretched when $\Delta M_{\rm RGB}$ is increased. No change of the cluster distance modulus can bring into agreement any of these two synthetic CMDs with the observed HB. Variations of $\Delta Y$ –keeping the reference $\Delta M_{\rm RGB}$ unchanged– stretch or compress the synthetic HB along the direction from the top-left corner of the CMD to the bottom-right one. Also in this case, variations of the cluster distance modulus do not compensate for the change of $Y$ distribution. ![Distribution of stellar mass (top panel) and initial $Y$ values (bottom panel) as a function of the colour $(B-V)$, for the stars in the synthetic CMD displayed in Fig. \[HBref\].[]{data-label="HBrefdistr"}](figpapHB47tuc_4.eps){width="\columnwidth"} A decrease of $\Delta Y$ to 0.025 and variations of $\Delta M_{\rm RGB}$ within less than 0.01 $M_{\odot}$ do still allow a satisfactory fit to the observed HB, according to the criteria described above, but larger variations are clearly ruled out because the resulting synthetic HB would clearly have a different shape than observed. Values of $\Delta M_{\rm RGB}$ below 0.20$M_{\odot}$ are totally incompatible with the observed HB morphology and location in the CMD. We have also experimented with a mass loss linearly dependent on the initial $Y$ distribution. Considering $\Delta M_{\rm RGB}$=0.23$M_{\odot}$ for the population with $Y_{\rm min}$, a synthetic HB with $\Delta Y$=0.03 and $\Delta M_{\rm RGB}$ increasing at most as 0.5 $\times$ $\Delta Y$ provides a fit to the observations of comparable quality as the baseline simulation. This implies $\Delta M_{\rm RGB}$ higher by just 0.015$M_{\odot}$ for the most He-rich component. Experiments with $\Delta M_{\rm RGB}$ decreasing with $Y$ show that at most $\Delta M_{\rm RGB}$ can decrease as 0.15 $\times$ $\Delta Y$, implying a negligible decrease of the RGB mass loss as a function of $Y$. ![As Fig. \[HBref\], but for the labelled values of $\Delta M_{\rm RGB}$ and $\Delta Y$ (see text for details)[]{data-label="HBvariations"}](figpapHB47tuc_5.eps){width="\columnwidth"} As an additional test we have calculated a synthetic HB by considering the reference $\Delta M_{\rm RGB}$=0.230$\pm$0.005 (Gaussian spread) for all $Y$, but with a different distribution of initial He abundances. We have considered in this case 70% of the stars with a Gaussian distribution of initial $Y$ characterized by mean value $<Y>$=0.275 and spread $\sigma(Y)$=0.007, and the remaining 30% with a very narrow Gaussian distribution with $<Y>$=0.258 and spread $\sigma(Y)$=0.0008. This choice stems from the results by @milonetuc, who found a bimodal MS for this cluster, corresponding to $\sim$0.02 difference in initial $Y$. The adopted distribution in our simulations has a difference of $\sim$0.02 between the mean values of the two Gaussians, and a total range $\Delta Y$=0.03, that is needed to cover completely the $V-(B-V)$ region occupied by observed HB. The 70/30 ratio comes again from @milonetuc analysis of the number ratio between the two populations of different initial He as a function of the distance from the cluster centre. For the same distance modulus of our reference simulation, mean $V$ and mean $(B-V)$ of the observed HB are again matched within 0.01 mag, although star counts as a function of colour and magnitude are slightly less well reproduced. The main point of this simulation is that a change of the initial $Y$ distribution of the HB stars does not affect the $\Delta M_{\rm RGB}$ required to match the CMD location of the observed HB. Analysis of the uncertainties ============================= In the previous section we have found that for the adopted reference \[Fe/H\]=$-$0.7, \[$\alpha$/Fe\]=0.4, $E(B-V)$=0.024, t=11.5 Gyr, our synthetic HB simulations require that RGB stars lose $\Delta M_{\rm RGB}$=0.23 $M_{\odot}$ (and have a range of initial He abundances $\Delta Y$=0.03) to match the observed location and morphology of the HB, corresponding to stellar masses in the range 0.63-0.69$M_{\odot}$. This value of $\Delta M_{\rm RGB}$ (and $\Delta Y$) is broadly in line with previous results based on synthetic HB modeling [@dicri; @gratton], but in total disagreement with the conclusions by @heyl_b about RGB mass loss, based on cluster dynamics. @heyl_b results specifically exclude HB masses of the order of 0.65$M_{\odot}$. In the following we will discuss quantitatively how our reference estimate of $\Delta M_{\rm RGB}$ may be affected by a series of observational and theoretical uncertainties. Cluster reddening, age and chemical composition ----------------------------------------------- The first obvious source of systematics is related to the range of reddening, chemical composition and age estimates found in the literature. We analyzed these effects by varying one parameter at a time. In all these cases the value of $\Delta Y$ required to reproduce the observations is unchanged compared to the baseline case. Increasing $E(B-V)$ (our baseline simulation has employed the lowest estimate of the cluster reddening) tends to increase $\Delta M_{\rm RGB}$. For example, assuming the widely employed value $E(B-V)$=0.04, we obtain $\Delta M_{\rm RGB}$=0.24$M_{\odot}$, whilst for the upper limit $E(B-V)$=0.055 we obtain $\Delta M_{\rm RGB}$=0.26$M_{\odot}$, e.g. we need lower masses to match the observed HB. As already mentioned, @mmc determined star-to-star variations around the mean reddening by at most $-$0.007 mag and +0.009 mag, respectively, with mean variations smaller than these extreme values. This amount of differential reddening will hardly affect the value of $\Delta M_{\rm RGB}$, as detailed below. Let’s assume –to maximize this effect– that the stars at the red edge of the observed HB have all a reddening 0.007 mag lower than the mean value. To compare with theory, their colours should then be increased by 0.007 mag (and their $V$ magnitudes increased by $\sim$0.02 mag) to reduce the observed HB to a single value of $E(B-V)$, causing a decrease of $\Delta M_{\rm RGB}$ by just $\sim$0.01$M_{\odot}$ in this extreme case. At the same time, assuming all stars along the blue edge of the [wedge]{} have a reddening 0.009 mag higher than the mean value, their colours should be decreased by the same amount and their $V$ magnitudes also decreased by $\sim$0.03 mag. This would require a negligible increase of $\Delta Y$, and $\Delta M_{\rm RGB}$ increasing with $Y$ as 0.
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1074, 4768, 13, 310, 417, 1293, 12794, 2495, 15, 187, 187, 8, 42, 651, 21434, 512, 1110, 970, 285, 490, 5302, 824, 5835, 281, 24033, 616, 1899, 285, 1642, 1880, 352, 310, 1663, 4409, 352, 1677, 253, 1495, 14, 33897, 10502, 2464, 187 ]	interesting to note that in its initial suit against the insurance company, one of the issues was whether the plaintiff also had to be discharged from his reserve status in the Guard to qualify him to collect the benefits. It appears that only after this became apparent to the plaintiff under the provisions of the policy that litigation was commenced against Cole, Hamilton and Sandell alleging a conspiracy to defraud 14 In his brief, Sandell also asserts that the military non-reviewability doctrine limits a court's review of the established relationship between enlisted military personnel and their superior officers. Chappell v. Wallace, 462 U.S. 296, 103 S.Ct. 2362, 76 L.Ed.2d 586 (1983). We decline to consider defendant Sandell's military non-reviewability argument as we find that the evidence is insufficient to support a conspiracy to defraud claim Microelectronic devices are often manufactured in and on silicon wafers and on other types other substrates. Such integrated circuits may include millions of transistors, such as metal oxide semiconductor (MOS) field effect transistors, as are well known in the art. MOS transistors typically comprise source, drain and gate regions, in which the gate material may typically comprise polysilicon. Polysilicon gates, however, can be susceptible to depletion effects, wherein an electric field applied to a polysilicon gate sweeps away carriers (holes in a p-type doped polysilicon, or electrons in an n-type doped polysilicon) so as to create a depletion of carriers in the area of the polysilicon gate near an underlying gate dielectric of the transistor. The depletion effect can add to the overall gate dielectric thickness in the MOS device. Recently, silicon germanium source and drain regions have been incorporated within transistors utilizing polysilicon gates, which greatly improves the performance of such transistors since the strained lattice of the silicon germanium regions enhance the electron and hole mobility within the channel of such a transistor, as is well known in the art. Metal gates, on the other hand, are not as susceptible to depletion effects as gates comprising polysilicon. Typical prior art microelectronic processes, however, do not incorporate both metal gates and polysilicon gates within the same device or integrated circuit. This is due, in part, to the complexity and cost of developing a microelectronic process that can reliably form both a metal gate structure and a polysilicon gate structure within the same microelectronic device or integrated circuit. It would therefore be advantageous to incorporate both a metal gate structure and a polysilicon gate structure with silicon germanium source and drain regions. The methods and structures of the present invention provide such a process.If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. i say conspiracy theory. the nfl is making sure the refs give the steelers enough leeway til big ben is healthy. the steelers are one of the afc's darling teams and it makes more sense for a team pushing for that wildcard birth to lose to give pitt some breathing room :-) theres ya another conspiracy. we'll play it out through the weekend. but yeah we played like doo doo on offense, refs have nothing to do with that. we couldnt block, we couldnt run, we couldnt move it through the air. but we were deflated early i think, which sucks because a team with veteran pressence shouldnt allow that to happen. the running into kicker was hit or miss, some games its called, others its not. ive seen blocked into kicker before and this is one that i prob would've called. but on the return you saw one of the bills players have his hands on a fins back and then he throws up his arms, they wouldnt show it on replays. ive said that i thought the 2nd PI call and the holding call on carroll were garbage, eeven the announcers said the holding call was garbage and they were pro buffalo the entire game. hartlines fumble i would say most refs would reverse the call and say incomplete pass, if they wouldve called the PI on hartline on the deep route it would've been huge. that is one that the WR gets most of the time on field. once again i think the pro-buf announcers even said hartlines offense-PI shouldnt been called. wake had to be reaching for an inhaler after the game cause he had arms around his neck as we was running by tackle so many times while being held. granted the refs did not stop our running game, we didnt block. they didnt stop our passing game (other than some bad calls), or our bad play calling. Good teams win inspite of adversary, we didnt, we're not a good team, yes i think we've lost a couple games this year cause of officiating, but if we were truly a good team the officiating wouldnt even matter. i just want to see us winning again, back when we were the leagues "darlings" the calls went our ways like it, believe it, or not. we become good again we'll get these calls, but right now they have to take care of their money makers, ala Pitt and Ind, and the best way to do that is by putting distance so "scrubs" like the fins dont make it in. Fins Up! 10-6 :-) I realize we played badly, but I was at the game with a Green Bay fan (completely neutral), and he pointed out several OUTRAGEOUS calls. The refs really are screwing us, it is not an excuse, it is a FACT. That being said, my friend was also able to call which plays the Dolphins would run on offense about 75% of the time. Our offense is painfully predictable. I swear i saw Sparano in a Fins uniform fist-pumping on the sidelines. If the refs were out to give the Fins a "screw job", I don't think they would have flagged the Bills nearly double what they gave the Fins. That being said, I think that the officiating needs improvement. Too many terrible calls this year league wide. Originally Posted by nyjunc The Giants absolutely win it all w/ Sanchez and they probably have more playoff wins and playoff apps if Sanchez is their QB, we probably don't even make a title game w/ Eli the last 2 years........ If the refs were out to give the Fins a "screw job", I don't think they would have flagged the Bills nearly double what they gave the Fins. That being said, I think that the officiating needs improvement. Too many terrible calls this year league wide. Again, the Bills were correctly called for obvious encroachment (neutral zone infractions), offsides, and face mask penalties (got away with one too). Those calls had no real impact on the game. Unjustly, the refs gifted the Bills major field position and kept drives going which in turn limited our time of possession, time and time again. Again, the Bills were correctly called for obvious encroachment (neutral zone infractions), offsides, and face mask penalties (got away with one too). Those calls had no real impact on the game. Unjustly, the refs gifted the Bills major field position and kept drives going which in turn limited our time of possession, time and time again. Whether your statement is true or not, it fails to elude to your "screw job" theory. Were there terrible calls and non-calls against the Fins? Perhaps. I'll chalk those up to poor officiating, not malevolent officiating.A bodybuilder, who gorged on junk food and drank eight cans of energy drink to gain weight, died of liver cancer caused by years of steroid abuse. Fitness enthusiast Dean Wharmby, 39, from Rochdale, died in July after a five and a half year long battle with with his illness. Obsessed with gaining size, to obtain the perfect bodybuilder's physique, he survived on a 10,000 calorie a day diet of burgers, pizzas and bacon sandwiches - washed down with seven to eight cans of energy drink. Scroll down for video Peak of his powers: Dean Wharmby, pictured, when on steroids and at the top of his bodybuilding game Final days: Mr Wharmby, pictured with partner Charlotte Rigby, in bed towards the end of his battle with cancer The dad of one also took anabolic steroids to boost his energy and sculpt his muscles - something coroner Lisa Hashmi said was a 'direct cause' of his death. At his inquest Mrs Hashmi said Mr Wharmby's death should serve as a reminder to people of the dangerous of using steroids. She said: 'I find on the balance of probabilities that in such a fit, health-conscious young man the most probable cause of his liver tumours was the misuse of anabolic steroids. 'To my mind, there is a direct, causal link with Dean's death. 'Dean's death and the precious loss of such a young life in such circumstances ought to send out a very clear message to all those involved in the body building and fitness industries. 'Use of anabolic steroids, which is apparently rife throughout, is not without inherent risk. 'I would urge all those using and abusing such drugs to reconsider their position and ask whether it is really worth it given the life-threatening risks.'
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481, 187, 187, 7580, 250, 440, 7393, 1593, 15119, 10538, 400, 8727, 711, 1205, 39564, 3377, 372, 42048, 4443, 363, 3611, 91, 278, 49935, 3737, 340, 10102, 1757, 2649, 3737, 13, 340, 440, 8943, 70, 7539, 343, 8306, 1593, 15119, 6234, 1753, 642, 572, 16749, 14076, 2297, 1118, 274, 345, 39920, 19664, 387, 261, 2399, 372, 7393, 1593, 10045, 313, 257, 774, 7860, 247, 3897, 2297, 1118, 375, 25937, 375, 372, 826, 2226, 14994, 13, 826, 704, 13, 826, 29717, 7860, 13, 3966, 860, 36497, 582, 396, 490, 250, 440, 1125, 860, 2649, 4173, 490, 15119, 4474, 1045, 32308, 9682, 66, 13, 546, 499, 6736, 8891, 13, 826, 10115, 795, 707, 5650, 30409 ]	ausas», o «despedido» de su Fundamento. Tal _existencia_ es previa y antecedente a toda reflexión relativa a su _esencia_ o _quididad_, a _lo que es (Wassein)_. Tal existencia es «ser ahí», _Dassein_, eso _que es (quod est)_ previo a su contenido eidético establecido por la reflexión. Ese existir preexiste a cuanto la razón pueda determinar. Da fundamento en general a esas determinaciones reflexivas de la razón. Pero ésta, en su autorreflexión, no puede crearlo ni producirlo (como creyó, por última vez, Hegel en su _Gran Lógica_, particularmente en su _Doctrina de la Esencia_ ). El Fundamento que la _reflexión_ siempre _presu-pone_ no puede ser establecido o _puesto_ (en forma de _positum_, o _tesis_, que el propio proceso de autorreflexión genera). Tal _positum_ fundamental se adelanta a toda reflexión; expide o expele el _existir_ ; y religa necesariamente toda razón o reflexión a ese existir. Y el existir se hace presente y manifiesto a través de la _revelación_ : una revelación que tiene su primera presencia en el mundo de la naturaleza; y la segunda en el ámbito _simbólico_ cuya exégesis primera y natural lo constituye la gran trama de las _mitologías_. Sobre esa doble revelación, primero natural, luego mítica, puede al fin promoverse la Revelación religiosa _kath' exogen_, que es para Schelling la revelación cristiana: la doctrina trinitaria de las Tres Potencias, y la concepción de la encarnación del _lógos_ ; pero sobre todo la apertura de un horizonte _espiritual_ como culminación de la revelación. Y la filosofía, si quiere realmente hallar al fin una fundamentación _positiva_, debe dialogar con esa triple revelación (natural, mítica, cristiana) con el fin de realizar su intención de constituir un Sistema orgánico y vivo emanado de un auténtico Fundamento _positivo_. De este modo Schelling intenta articular y conjugar, en una verdadera _síntesis espiritual_, una _filosofía positiva_ que se despliega como filosofía de la revelación, que tiene el primer peldaño en la filosofía de la naturaleza y el segundo en la filosofía de la mitología, y una _filosofía negativa_ que pretende, según presupuestos idealistas y sistemáticos (siguiendo la tradición cartesiana, kantiana, o incluso hegeliana), incoar un proceso de autoproducción que sea, a la vez, una genuina autofundamentación. Sólo que esta última debe siempre presuponer el _positum_ de aquel Fundamento originario y matricial, verdadero Abismo, _Ungrund_, del cual sale despedida la _ex-sistencia_ (eso _que es_ fuera de su Causa). Y esa existencia, que al ser despedida da lugar a su propia _revelación_, no puede ser deducida por la _filosofía negativa_ : no puede inferirse del «movimiento esencial», o movimiento de autorreflexión, tal como pretende Hegel en su _Doctrina de la Esencia_, en su _Lógica Mayor_. Schelling, pues, apunta a una _conmodulatio_, o _armonía oppositorum_, entre esas dos grandes ramas del mismo tronco filosófico: la tradición de una «reflexión» filosófica que, al modo de la antigua y medieval, presuponga siempre el _dato_ positivo (previamente implantado, «puesto») de una _revelación_ que se produce en clave _simbólica_ (y cuya exégesis corre a cargo de la mitología y de la religión revelada); y la tradición de la modernidad cartesiano-kantiana, seguida por el propio Schelling y por Hegel, según los postulados metódicos y críticos del idealismo alemán, con su voluntad sistemática por autoengendrar en y desde la propia reflexión racional todo el conjunto de lo existente, de manera que el proceso de gestación de realidad coincida con el propio proceso de auto-fundamentación del pensamiento. Schelling apunta con todo ello hacia el horizonte de un posible nuevo eón en el cual tal conjunción copulativa entre revelación simbólico-religiosa y reflexión racional pudiera consumarse: la expectativa misma relativa al último de los eones de este ciclo espiritual. Pero esa expectativa de Schelling termina en un «acorde de séptima». La síntesis de filosofía positiva y de filosofía negativa no llega a producirse. Schelling muere sin hallar el broche áureo que sellara los dos lados de una realidad espiritual escindida. En lugar de eso Schelling pone punto final a este eón idealista y romántico abriendo el largo y tortuoso curso del régimen de experiencia y reflexión del mundo contemporáneo, que parece instalarse justamente en esa fisura abierta. En ese mundo que se inicia en la década de los cuarenta del siglo XIX la escisión entre el _factum_ positivo al que debe recurrir toda reflexión y ésta parece ahondarse hasta el paroxismo. Se inicia así el régimen de una _cesura dia-bálica_ que domina de modo hegemónico desde entonces hasta nuestro presente histórico. Todo el pensamiento contemporáneo tiende a instalarse en esa cesura, rehuyendo siempre todo intento por suturarla mediante una genuina síntesis espiritual. De hecho, se retiene de la filosofía del último Schelling la premisa de que la reflexión debe ser antecedida por una _base real y material_ que no puede ser autofundamentada por la Razón. Sólo que ese Fundamento pierde entonces el halo místico y sagrado que conservaba en la filosofía de Schelling, regiamente instalada en el eón místico y romántico. No es ya ese _Grund-Ungrund_, o fundamento abismal, que Schelling había recreado a partir de la inspiración que le proporcionaba el _Mysterium Magnum_ de Jakob Böhme, su libro de cabecera. Este recurso a fuentes esotéricas (teosofía mística de Böhme, tradiciones cabalistas) característico del último Schelling deja paso a una interpretación _desmitificadora_ de la «base material», del fundamento natural y físico, o de la idea de Fundamento. Tal es el paso que dan, en este punto, los seguidores de la crítica de Schelling al idealismo absoluto de Hegel: Feuerbach, Marx, Engels, Bakunin, el propio Kierkegaard. El _hiato_ entre razón y revelación, o entre el fundamento _real_ y la reflexión filosófica promueve una constante basculación entre una interpretación _positivista_ del _positum_ (que será para Feuerbach la naturaleza material, y para Marx y Engels el mundo material-social de la economía política) y una interpretación radicalmente crítica respecto a todas las pretensiones de la Razón por suturar ese _hiato_ (así Kierkegaard). Entre un racionalismo positivista desengañado de toda embriaguez mística y romántica, y un evidente «irracionalismo» que no quiere ya negociar con ningún atisbo de racionalidad (en relación a los negocios supremos de la existencia, la fe, la salvación, etcétera), se abre un auténtico abismo por el cual circula, en plena crisis, la gran _cesura dia
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479, 432, 1146, 660, 15416, 407, 12413, 952, 13, 285, 1014, 10073, 479, 347, 309, 12668, 281, 253, 5275, 8554, 5092 ]	should make that more precise: with-syntax-table temporarily alters the current syntax table of whichever buffer is current at the time the macro execution starts. Other buffers are not affected.Tag: Hope One of the most difficult questions I’ve had to answer after our family’s 3-week vacation to the States was “How was your trip?”. Every single time a friend or a colleague asked me this, I took a deep breath, smiled, and said: “It was good! Really fun!” But, behind those answers was a heart breaking inside of me. Yes, by God’s grace, there were good and amazing highlights which I hope to share sometime soon. However, I couldn’t just let go of the fact that our family went through an emotional roller coaster ride that continued even a month after we got back to the Philippines. We went home to the same house each day and had occasional chats, but there was definitely an elephant in the room. PRIDE IN THE FAMILY The trip was supposed to be a fun time with the family because of three main reasons: 1) Our eldest sister’s wedding and meeting the extended family in Hawaii, 2) Our family reunion with my father’s side, and 3) Our whole family’s first time to travel the States together. But while we were still in the States, our different types of personalities clashed almost every day. From the smallest concerns to the biggest problems we encountered, the pride in us took over our hearts and minds. Unfortunately, this caused us to stumble and sin not only in our thoughts, but also in the harsh and unloving words that we carelessly threw against each other. When someone made a mistake, some of us were quick to judge and comment about it. When someone made suggestions, some of us chose to disregard and belittle them. When someone opened up that he/she was hurt, the other side became defensive. When we experienced delays, hassles, or detours during the trip, blaming and getting annoyed at each other became a normal response. Moreover, smiling for the camera in between these moments was the cherry on top! It was very tiring and frustrating. INDIFFERENCE IN THE FAMILY As each day passed by, I kept telling God about my disappointment and heartbreak because of our family’s situation. There were moments when I would cry or cringe especially when I would see myself and my other family members being joyful with others, yet having not much emotion or interest back at home. It broke my heart to see how it was normal for us to worship God and serve others when we ourselves weren’t honoring God in our relationships in the family. I also noticed that some of us preferred staying out late instead of going home early to spend more time with the family. In addition, some of us kept ourselves busy with work or other interests, since it was more convenient compared to dealing with the problem. In a nutshell, our family was already giving up on each other. “Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God. – Psalm 43:5 HUMILITY IN THE FAMILY Last Saturday, during a road trip with my older sister to a coffee farm, I had the opportunity to open up to her and share what I was feeling and thinking of, in relation to the elephant in the room. I said things like: “I honestly don’t know my parents and siblings anymore. We don’t make time for each other which causes us to be quick in judging and not understanding each other.” and “I’ve been ranting about this to God almost every day. I feel like He’s telling me to stop ranting and to start doing something about it!” Our exchanges of experiences led us to agreeing that we needed to resolve issues and have a family meeting. We just couldn’t imagine seeing this problem snowball into something bigger in the years to come. I sent out a chat invite to our family’s group chat and surprisingly, they all (parents, older sister, and younger brother) confirmed their attendance for the next day. Ironically, that same road trip, I let my pride take control of me and it caused a tension between me and my sister (which I shared in my previous POST). But, God used that experience for me to understand the value and blessing of humility and by His grace, this inspired me to be intentional in praying for and facilitating our family meeting that weekend. It was one of the awkward moments I’ve had with the family. Seeing them walk in the coffee shop one by one and knowing that we all had unresolved issues in our hearts. But somehow, God was encouraging me to trust that He is more than able to restore our relationships in His perfect timing. After Mom opened in prayer, I started to lead the discussion by sharing that the purpose of our talk that night was for us to be aware of the situation we had and to trust that God will help us restore what was broken. I then asked everyone (including myself) two questions that night. The first question was: “What changes do you desire to see in our family?”. This was our chance to let each other know about the improvements that we wanted to see in the members of the family. After around 10 minutes, I asked them the second question: “What changes do you desire to see in YOURSELF, in relation to the family?”. I remember seeing some of their eyes widen and hearing some say “ohh my!”. I guess it was a question that they did not expect. After everyone finished typing their answers on their mobile phones, I said: “Okay! It’s now time to share our answers to the group. Let’s begin with question… #2.” By God’s grace, He inspired me to set the tone of humility in our discussion by starting with the second question. Knowing our family (based on the previous open forums we’ve had in the past years), whenever we first shared about family issues and problems because of each other, our conversations did end up having action steps, but they also turned a bit sour afterwards. Sometimes, there would still be conversations after the open forum where some of us would say, “I still felt that I wasn’t understood when I opened up…” and all those similar responses. So, for our recent family meeting, it was refreshing and very humbling for each of us to start the discussion by admitting our own weaknesses, shortcomings, and desires to improve ourselves within the context of family. By the time we moved on to question #1, the issues and concerns shared were willingly welcomed by each member. After a loooong time, I sincerely saw how each member was intentional in hearing out and understanding where the hurting member was coming from. There were no defensive or harsh comments made and when we were almost leaning towards a tension, the other members helped in balancing the conversation. Not only did we get to know each other and our hurts more, we also had the opportunity to forgive, to ask for forgiveness, and to believe in the best towards each other. Hugs were given, tears were shed, funny comments were occasionally said, tips to love each other were shared, and walls among us were slowly being destroyed. HOPE FOR THE FAMILY We ended the night by encouraging each other to grow in our relationship with Jesus and in our love for each other, by the power of the Holy Spirit. My heart was overjoyed, not because all of our family concerns were solved, but because we found hope in Jesus. In spite of our weaknesses, He is more than able to transform our hearts and do miracles in our families, no matter how simple or hopeless the situations and problems may be. All it takes is a step of faith when He calls us to act on it and trust in Him. You too might wonder: “Is there hope for my broken family?” I think you already know the answer to it. Will you believe it? :) “May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.” –Romans 15:13 On my way home from work last Friday night, I recorded a song in the car, out of the overflow of my heart. Just a few seconds after I said thanks to God for allowing me to finish it, I heard a loud, consistent beat at the right side of my car. A motorcyclist who drove by me then, signaled me to stop and look at my wheel. During the next three minutes, my world slowed down as I went out of the car to inspect the damage. My jaw dropped as I saw my exploded tire at the side of the passenger’s seat. My mouth blurted out, “Shocks, Lord. Is this really happening? Please help me.” Within a minute, even before I could call my dad, another motorcyclist stopped by to ask if I needed help. My initial reaction was “I hope this guy isn’t sketchy.” But in my desperation, I said, “Yes, please!” He spent the next 10 minutes, going through my car tools at the back, setting up my emergency signals, and trying to release the spare tire that was hidden under my car. I remember telling him countless times how much I appreciated his help and how it really was impossible for me to change my tire by myself. After a few minutes, another motorcyclist stopped by to offer assistance. They ended up helping each other as they raised my car, changed my tire, protect me from being scammed by tow people, and even assist me as I drove to the nearest vulcan
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10303, 323, 5415, 6973, 285, 10904, 13653, 11878, 323, 8985, 6973, 13, 285, 3969, 5325, 2462, 7162, 11508, 15, 187, 187, 3074, 6260, 497, 31539, 407, 2825, 285, 253, 17705, 323, 7605, 8453, 369, 873, 347, 475, 2141, 11, 24832, 17, 6256, 1762, 313, 9389, 14, 29551, 481, 1876, 6260, 497, 2684, 970, 253, 7605, 3694, 5522, 33918, 2715, 898, 15, 19, 15, 187, 187, 9340, 1712, 1704, 19, 94, 187, 6877, 187, 187 ]	In 1949, Hadassah inaugurated the Henrietta Szold prize, which was awarded that year to Eleanor Roosevelt.The Henrietta Szold Institute, National Institute for Research in the Behavioral Sciences, located in Jerusalem, is named after her. The institute is Israel's foremost planner of behavioral science intervention and training programs.Public School 134 on Manhattan's Lower East Side in New York City is also named after her.In 2007, Szold was inducted into the National Women's Hall of Fame in Seneca Falls, New York.In Israel, Mother's Day is celebrated on the day that Szold died, on the 30th of Shevat. In the northwest corner of Szold's home city of Baltimore, Szold Drive, a short street in a residential neighborhood with homes built in the 1950s, is named after her as well. The northernmost part of the street is in Baltimore County. In New York City, Szold Place, formerly Dry Dock Street runs from East 10th Street to East 12th Street in the East Village neighborhood of Manhattan. == See also == Benjamin Szold Robert Szold Zip Szold Cancer causes 8·2 million deaths each year worldwide, accounting for 13 % of all deaths. Annual numbers of new cancer cases worldwide are expected to rise by 70 % over the next two decades^(^ [@ref1] ^)^. While greater uptake of screening and increasingly effective treatments have reduced mortality rates for some cancers^(^ [@ref2] ^--^ [@ref4] ^)^, there is a growing realization that primary prevention through lifestyle and environmental interventions may offer a more sustainable solution for reducing cancer burden^(^ [@ref1] ^,^ [@ref2] ^,^ [@ref5] ^)^. Estimates for the impact of modifiable risk factors on cancer incidence vary according to the assumptions used to create the statistical models and on the source and quality of the underlying data^(^ [@ref6] ^,^ [@ref7] ^)^. However, regardless of the variation in different population-attributable fractions for each risk factor, there is a general consensus that use of tobacco, physical inactivity, low fruit and vegetable intake, high intake of red and processed meats, overweight and obesity, and use of alcohol are responsible for up to 30 % of cancer incidence overall^(^ [@ref8] ^--^ [@ref13] ^)^. In 2007, the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) produced a series of population goals and personal recommendations for cancer prevention based on these modifiable behaviours and health-related variables^(^ [@ref14] ^)^. The rationale was to provide a robust evidence base to inform the development of policies and interventions to help reduce cancer risk in the general adult population. However, before moving towards policy development, it is important to understand more about the concurrence between existing health-related variables and behaviours and current recommendations. Such information may be useful in identifying priority areas for further investigation and intervention. The aim of the current study was to explore the extent of adherence to WCRF/AICR cancer prevention recommendations for individuals^(^ [@ref14] ^)^, based on behaviours and health-related variables reported by adults enrolled in Alberta's Tomorrow Project (ATP), Alberta, Canada. A comprehensive overview of adherence to cancer prevention guidelines and the associated influential factors can inform cancer prevention strategies and assist in designing consistent targeted strategies to increase population adherence to evidence-based cancer prevention guidelines. Methods {#sec1} ======= Study population {#sec1-1} ---------------- Between 2001 and 2009, ATP enrolled 31 212 Albertans aged 35--69 years, with no personal history of cancer other than non-melanoma skin cancer, into a cohort. Participants were recruited by random digit dialling using Regional Health Authority boundaries as the sampling frame. In the first recruitment wave, a second eligible adult within each household was recruited (n 382, 1 %) if possible; but this practice was discontinued in subsequent recruitment waves^(^ [@ref15] ^)^. Recruits were mailed an information package and were considered enrolled if they returned a completed Health and Lifestyle Questionnaire (HLQ) and signed consent form. Three months after enrolment, participants received two additional questionnaires assessing past-year dietary habits and physical activity. Response rate to the random digit dialling call has been estimated at 32 %^(^ [@ref15] ^)^ and response rate of those individuals to enrolment was 49 %. Questionnaires {#sec1-2} -------------- The HLQ queried self-reported sociodemographic, behavioural and health-related variables including age, marital status, education, employment status, annual household income, tobacco use and exposure to second-hand smoke, family health history and body measurements (height, weight, waist and hip circumferences). In addition, participants indicated whether or not a doctor had ever told them that they had any of the following health conditions: high blood pressure, angina, high blood cholesterol, heart attack, stroke, emphysema, chronic bronchitis, diabetes, ulcerative colitis, Crohn's disease, hepatitis or liver cirrhosis. Participants who answered 'yes' to having received a diagnosis of any of these conditions were deemed to have a personal history of chronic disease. Past-year diet, including supplement use, was assessed by the US National Cancer Institute's 124-item Canadian Diet History Questionnaire I (CDHQ-I), an FFQ adapted for use in Canada^(^ [@ref16] ^,^ [@ref17] ^)^. Recent evidence supports that the food list in CDHQ-I is representative of the foods commonly consumed by Canadian adults^(^ [@ref18] ^)^. CDHQ-I data were analysed using Diet\Calc version 1.4.3 (National Cancer Institute, Bethesda, MD, USA) to estimate mean daily intakes of nutrients and food group servings, as well as supplement use. Past-year recreational activities were assessed using a validated Past Year Total Physical Activity Questionnaire (PYTPAQ)^(^ [@ref19] ^)^. Total minutes per week performing leisure activities at moderate (3--6 MET, where MET=metabolic equivalent of task) and vigorous (\>6 MET) intensities were calculated based on reported activities. Cancer prevention recommendations adherence score {#sec1-3} ------------------------------------------------- A composite score reflecting adherence of reported behaviours and health-related variables to seven selected WCRF/AICR personal recommendations for cancer prevention was constructed for each participant using data collected upon enrolment to ATP. Recommendations included were those that addressed the general adult population and were identified as quantifiable using baseline ATP data. Recommendations addressing special groups (cancer survivors, breast-feeding women, people living in specific geographic regions) or that were not quantifiable with ATP data were excluded. It was not possible to quantify adherence to some recommendations (consume fast foods sparingly, avoid sugary drinks, limit sedentary habits), while the data required to quantify some other recommendations were not available for ATP participants (consume energy-dense foods sparingly, limit refined starchy foods, eat relatively unprocessed grains and legumes, avoid salt-preserved, salted and salty foods, do not eat mouldy cereals and pulses, avoid weight gain and increases in waist circumference throughout adulthood, ensure body weight through childhood and adolescent growth projects towards the lower end of the normal BMI range). Considering the WCRF/AICR panel emphasized the importance of tobacco exposure for cancer risk^(^ [@ref14] ^)^ in addition to the other recommendations, second-hand smoke exposure and cigarette smoking were also included in the composite score. Participants scored 1 point for each recommendation met and 0 if it was not met. Recommendations included in the current analyses were: BMI within normal range (18·5--24·9 kg/m^2^), no daily exposure to tobacco during the past year, no more than two alcoholic drinks daily for men or no more than one daily for women, consumption of five or more servings of fruit and vegetables daily, consumption of less than 500 g of red meat weekly, not taking any dietary supplements and performing at least 210 min of moderate- or vigorous-intensity recreational physical activity weekly. The composite score ranged from 0 (least adherent) to 7 (most adherent). Statistical analyses {#sec1-4} -------------------- Descriptive statistics were presented as group means and standard deviations for continuous variables and as counts and percentages for categorical variables. Multiple linear regression models were used to explore associations between participants' composite scores and potential influential characteristics. Multiple logistic regression models were used to explore the association between participants' adherence to each of the seven components of the composite score and potential influential factors. All estimation models were adjusted for age (at categorical level: 35--49, 50--59, 60--70 years), marital status (living without partner, living with partner), education level (high school or lower, college, university), employment status (not employed, retired, employed part-time, employed full-time), annual household income (\<\$CAN 70 000, ≥\$CAN 70 000), first-degree family history of cancer (no, yes), first-degree family history of chronic disease (no, yes) and personal history of chronic disease (no, yes). Analyses of the associations were reported as adjusted regression coefficients for continuous outcomes and adjusted odds ratios for binary outcomes, and corresponding 95 % confidence intervals. All analyses were stratified by sex and the criterion for statistical significance was set as α*≤0·05 (two-tailed). All analyses were performed using the statistical software package SAS version 9.2. Results {#sec2} =======
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13, 24112, 13, 42953, 13, 285, 20222, 13, 1024, 512, 8228, 598, 285, 10362, 347, 17874, 285, 816, 25346, 285, 1753, 561, 273, 253, 2659, 273, 427, 1596, 571, 13, 873, 562, 281, 20269, 247, 19796, 33435, 28, 616, 20269, 5644, 731, 715, 253, 18557, 13, 2584, 2802 ]	their picture taken as it was such a bizarre incident. North West Motorway Police tweeted: “Report of female being assaulted on M62, vehicle stopped pair of extras making to a job - posing as Zombies - takes all sorts.”Nymex not worried by screen trading glitch New York Mercantile Exchange (Nymex) said it has corrected a technical glitch that downed its electronic trading platforms last week and reassured traders that the problem was not a harbinger of doom for its side-by-side trading plan. Market participants have raised questions over the ability of Nymex's systems to cope with its forthcoming switch to side-by-side screen and pit trading (see FO Week Vol 11 No 6).Search form Your Pain Clinic Appointment You have been referred to the pain service because your pain is interfering with your quality of life and your ability to function effectively. Pain that persists can be distressing and disabling. Most of the interventions we offer will help about one third of patients and will reduce the intensity of pain but not take it away. Response to treatment varies from person to person, even if they seem to have the same symptoms. Your pain specialist will make an assessment of you and of your pain and decide which treatment(s) might be helpful in your case. Injections may help some individuals but they often only have a limited effect and should be part of a multidisciplinary (joined) management programme. A decision on an injection will only be made after a full discussion with the patient if it is considered appropriate. With support, many patients can start to exercise, engage with hobbies and resume work (full or part-time). We want to help people move forward and for this reason it is unhelpful for us to disable our patients by saying that they are unfit to work. Our Pain Clinic Service works to support you and your GP to manage your pain. The treatments we offer are familiar to your GP and your GP will be experienced in managing day-to-day queries about your pain treatment. Your pain specialist may make a pain treatment plan for you and your GP to follow together. Your GP will be able to deal with queries and if you have a problem with medication you can also discuss this with your pharmacist Treatments we offer include: Medication review TENS 1 Acupuncture course Injections as part of a multidisciplinary approach to pain management Stimulation techniques Pain Management Programme (PMP) courses are an internationally used approach to the rehabilitation of people with chronic pain conditions. They include specialist guidance about mobility and exercise, following a detailed assessment. Back Pack is group programme specifically for people with recurring episodes of back pain. Self-Management Programme (SMP). These courses are led by one of the specialist healthcare professional and a Lay Tutor, who is someone who has benefited from one of our courses as a patient and has gone on to train in the delivery of the courses. These SMP courses do not include guidance around exercise, and participants will usually have some form of exercise which they are already involved in, or which they could re-start at a low level themselves during the course. Sleep course Individuals one-to-one sessions for a particular reasons. Individual work is usually a stepping-stone towards attending a program.""" Simple script that checks if a checkpoint is corrupted with any inf/NaN values. Run like this: python inspect_checkpoint.py model.12345 """ import tensorflow as tf import sys import numpy as np if __name__ == '__main__': if len(sys.argv)!= 2: raise Exception("Usage: python inspect_checkpoint.py <file_name>\nNote: Do not include the.data.index or.meta part of the model checkpoint in file_name.") file_name = sys.argv[1] reader = tf.train.NewCheckpointReader(file_name) var_to_shape_map = reader.get_variable_to_shape_map() finite = [] all_infnan = [] some_infnan = [] for key in sorted(var_to_shape_map.keys()): tensor = reader.get_tensor(key) if np.all(np.isfinite(tensor)): finite.append(key) else: if not np.any(np.isfinite(tensor)): all_infnan.append(key) else: some_infnan.append(key) print "\nFINITE VARIABLES:" for key in finite: print key print "\nVARIABLES THAT ARE ALL INF/NAN:" for key in all_infnan: print key print "\nVARIABLES THAT CONTAIN SOME FINITE, SOME INF/NAN VALUES:" for key in some_infnan: print key print "" if not all_infnan and not some_infnan: print "CHECK PASSED: checkpoint contains no inf/NaN values" else: print "CHECK FAILED: checkpoint contains some inf/NaN values" [Stress and alcohol: research with experimental animals]. Research on the interaction of ethanol and stress with experimental animals are briefly reviewed. There might be the two aspects of the interaction of stress and ethanol, i.e., how stress affects ethanol ingestion and response to ethanol, and how ethanol modifies stress response. In general, stress increases ingestion of ethanol in animals exposed to various stresses including electric shock, immobilization and psychological or emotional stresses, wherein the psychological or emotional factors were predominantly involved. However, in most cases, ethanol ingestion is increased after release from stress not during exposure to stress. A variety of stressful stimuli caused marked increases in the neurotransmitter release in many brain regions. Immobilization stress increased noradrenaline release in the extended brain regions in rats. These increases were significantly attenuated by pretreatment with ethanol in the rat amygdala and locus coeruleus, but not in the hypothalamus, although ethanol by itself increased noradrenaline release in the hypothalamus. Further, psychological stress, wherein the rats were given no electrical shock, but exposed to the emotional responses such as struggling, vocalization, jumping and defecation shown by the other electrically-shocked rats, increased noradrenaline release preferentially in the hypothalamus, amygdala and locus coeruleus. Among the former two regions, stress-induced increases in noradrenaline release were significantly attenuated by ethanol in the amygdala, but not in the hypothalamus. Together with the finding that increases, in noradrenaline release are closely related to the provocation of anxiety and/or fear, ethanol, in part, reduced tension, as mentioned in the tension reduction hypothesis, by attenuating stress-induced increases in noradrenaline release in the amygdala and locus coeruleus. Moreover, ethanol, administered i.p. and directly through the microdialysis probe, increased dopamine release in the nucleus accumbens assessed by in vivo microdialysis, similarly as addictive drugs such as amphetamine did. This might be, in part, neurochemical basis for motivation of repeated drinking of ethanol.Q: Returning a pointer using get method from class and using & to take it in recursively So I am just working on some code and have kind of stumped myself I have a class Node and another class BinaryTree: class Node { public: Node(); Node(int thedata, Node right, Node* left):data(thedata), right_pointer(right), left_pointer(left){}; int get_data(){return data;} Node* get_right() {return right_pointer;} Node* get_left() {return left_pointer;} private: int data; Node* right_pointer; Node* left_pointer; }; class BinaryTree { private: Node* root; void add_tree_node(Node& root,int data); void print_tree(Node root); public: BinaryTree(); void print_tree(); void add_tree_node(int data); }; My issue is with this command: add_tree_node(root->get_right(), data); I get an error saying: no instance of overloaded function. which get_right() returns a pointer to the pointer and was wondering if there was a better way of doing this instead of the two options below. when I do this: Node* right = root->get_right(); add_tree_node(right, data); or add_tree_node(root->right_link,data); it works and I understand why it works because we are passing in the pointer itself and not the value. A: Node* &get_right() {return right_pointer;} Node* &get_left() {return left_pointer;} Tag Archives: personal identity Post navigation Readers of C. S. Lewis’ The Lion, The Witch, and the Wardrobe will remember the novel’s dramatic ending: Peter, Lucy, Edmund, and Susan, now all grown up and ruling as noble and just kings and queens of the land of Narnia, set out to hunt a mysterious stag; their hunt leads them into the woods, toward ‘
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Console. They do have plans for adding the feature,but It'll come in the future. For now, you can watch their updates here: https://firebase.googleblog.com https://firebase.google.com/support/releases Their support suggested me to wipe all data and to lock down the database to prevent any usage, as a work-around for now. Just remembering that having multiple instance is only possible if you have a Blaze account. As the desire for enhanced communication bandwidth escalates, transmission media are pressed to convey information at higher speeds while maintaining signal fidelity and avoiding crosstalk. For example, a single communication cable may be called upon to transmit multiple communication signals over respective electrical conductors concurrently. Such a communication cable may have two or more twisted pairs of insulated electrical conductors (“twisted pairs”) that are separated by a conventional element disposed in the core of the communication cable. The conventional element attempts to maintain some level of relative positioning of the twisted pairs within the cable for addressing crosstalk, which has posed perennial design challenges for high-performance 4-pair data cables. In many circumstances, movement of twisted pairs relative to one another within conventional communication cables can lead to decreased signal performance. For example, when a conventional cable is installed, external and internal forces may reorient the twisted pairs within the cable to positions at which crosstalk may escalate and signal quality may diminish. Accordingly, what is needed is an improved capability for orienting signal conductors, electrical conductors, and/or twisted pairs within a communication cable. A need exists for a technology that can improve placement of electrical conductors within a communication cable. A need also exists for a capability to maintain relative positions of electrical conductors within a communication cable while the cable is deployed, installed, or otherwise moved, twisted, bent, and or unrolled. A further need exists for a pair positioning member that can be readily anchored within a communication cable to facilitate robust positioning. A need further exists for a pair positioning member having reduced material relative to conventional technology, to facilitate lower manufacturing and material costs, lighter weight cables, and less material to generate flames or smoke during burn tests. A capability addressing one or more such needs or some other related deficiency in the art would enhance bandwidth that a communication cable can carry reliably.--- abstract: 'For $\lambda$ an $n$-th power of a unit in a finite chain ring we prove that $\lambda$-constacyclic repeated-root codes over some finite chain rings are equivalent to cyclic codes. This allows us to simplify the structure of some constacylic codes. We also study the $\alpha +p \beta$-constacyclic codes of length $p^s$ over the Galois ring $GR(p^e,r)$.' author: - 'Aicha Batoul, Kenza Guenda and T. Aaron Gulliver [^1]' title: \| Some Constacyclic Codes over\ Finite Chain Rings --- Introduction ============ Constacyclic codes are a generalization of cyclic codes. While the class of simple root constacyclic codes is well known over fields, little is known about repeated root constacyclic codes over fields, and even less about these codes over finite chain rings. Recently, simple root constacyclic codes over finite chain rings and the repeated root cyclic and negacyclic codes over finite fields have been studied [@G-G; @G-G12]. In this work, we generalize the results in [@G-G; @G-G12]. The structure of constacyclic codes over some chain rings is given, as well as conditions on the equivalence between constacyclic codes over finite chain rings and cyclic codes. As a special case, we consider the structure of $(\alpha + \beta p)$ constacyclic codes of length $p^s$ over $GR(p^e,r)$. Besides contributing to what is known concerning this class of codes, our motivation in studying these codes comes from the fact that repeated root cyclic codes contains many optimal codes, and the decoding complexity can be low as shown by Van Lint in the binary case [@lint] and Byrne et al. [@byrne] for codes over $Z_4$. Furthermore, repeated root cyclic codes have found applications in DNA computing [@watada]. The remainder of this paper is organized as follows. In Section 2, we give some preliminaries results concerning finite chain rings. Section 3 gives conditions on the scalar equivalency between constacylic codes and cyclic codes over finite fields (for both simple and repeated roots). In Section 4, we generalize some results of Section 3 to finite chain rings. Finally, the structure of $(\alpha + \beta p)$-constacyclic codes of length $p^s$ over $GR(p^e,r)$ is considered in Section 5. Preliminaries ============= A finite chain ring is a finite local, principal commutative ring $R$ with $1\neq 0$ such that its ideals are ordered by inclusion. Hence if $\langle \gamma \rangle$ is the maximal ideal of the finite chain ring $R$, then $ \gamma $ is nilpotent with nilpotency index some integer $e$. The ideals of $R$ form the following chain $$<0>= \langle\gamma^e\rangle \subsetneq \langle\gamma^{e-1}\rangle \subsetneq \ldots \subsetneq \langle\gamma\rangle \subsetneq R.$$ The simplest examples of finite chain rings are the finite fields. Since they are chain rings with nilpotency index 0, the nilradical of $R$ is $\langle\gamma\rangle$, so all the elements of $\langle\gamma\rangle$ are nilpotent. Therefore the elements of $R\setminus \langle\gamma\rangle$ are units. We denote this group by $R^*$. Since $\langle\gamma\rangle$ is a maximal ideal, the residue ring $\frac{R}{\langle\gamma\rangle}$ is a field which we denote by $K$. The natural surjective ring morphism is given by $$\label{eq:over} \begin{split} \mu: R& \longrightarrow K\\ a &\longmapsto \mu (a)=a +\langle \gamma \rangle \end{split}$$ The map given in (\[eq:over\]) extends naturally to a map from $R[x] \longrightarrow K[x]$. A polynomial $f$ of $R[x]$ is called basic irreducible if $\mu(f)$ is irreducible in $K[x]$. Let $\|R\|$ denote the cardinality of $R$. If $\|K\|=q=p^r$ for some integer $r$, then $$\label{cardinality-of-R} \|R\|=\|K\|\cdot\|\langle\gamma\rangle\|=\|K\|\cdot \|K\|^{e-1}=\|K\|^e=p^{er}.$$ A code $C$ of length $n$ over $R$ is a subset of $R$. If the code is a submodule we say that the code is linear. Here, all codes are assumed to be linear. \[lem:cardinal2\]([@Ana]) Let $R$ be a finite commutative chain ring with maximal ideal $\langle \gamma \rangle $, residue field $K$ and nilpotency $e$. Then the following hold: 1. the distinct proper ideals of $R$ are $\langle \gamma^i\rangle$, $i=1,2,\ldots,e-1$; 2. for $i=1,2,\ldots,e-1$, $\|\langle \gamma^i\rangle\|\, =\,\|K\|^{e-i} $. A special case of finite chain rings are the called Galois rings. The Galois ring $GR(p^e,r)$ is a ring of characteristic $p^{e}$ and cardinality $ p^{er}$. We have $ GR(p^e,1)={\mbox{\msbm Z}}_{p^e}$ and $ GR(p,r)= F_{p^{r}}$. The Galois ring $GR(p^e,r)$ is a local ring with maximal ideal $\langle p \rangle = p GR(p^e,r)$ and residue field $GR(p^e,r) /p GR(p^e,r) = F_{p^{r}}$. If $ f(x)\in {\mbox{\msbm Z}}_{p^e}[x]$ is a monic basic irreducible polynomial of degree $r$, then the Galois ring of degree $r$ over ${\mbox{\msbm Z}}_{p^e}$ is the residue class ring $$GR(p^e,r)\,=\,{\mbox{\msbm Z}}_{p^e}[x] /(f(x)).$$ If $\xi$ is a root of $f(x)$, then $GR(p^e,r) = {\mbox{\msbm Z}}_{p^e}[\xi]$, i.e., $GR(p^e,r)$ is a free module of rank $r$ over ${\mbox{\msbm Z}}_{p^e}$ with $\{1,\xi;\xi^{2},\dots,\xi^{r-1} \} $ as a basis. All Galois rings of the same orders are isomorphic. There exists an element $\xi$ of order $p^{r}-1 $ in $GR(p^e,r)$ called a primitive element of $GR(p^e,r)$, $\xi$ is a root of a unique monic basic primitive polynomial of degree $r$ over ${\mbox{\msbm Z}}_{p^e}$ and dividing $ x^{p^{r}-1}-1$ in ${\
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320, 1077, 31115, 323, 667, 1361, 15, 187, 187, 34, 27, 187, 187, 4553, 368, 13542, 1818, 253, 5084, 4454, 13, 368, 476, 897, 2451, 15, 7886, 426, 26194, 1223, 45527, 253 ]	).toHaveBeenCalledTimes(1); })); }); }); Raman Characterization of Nanoparticle Transport in Microfluidic Paper-Based Analytical Devices (μPADs). There is great interest in the use of microfluidic paper-based analytical devices (μPADs) for low-cost diagnostics. In this contribution, we illustrate the utility of Raman spectral imaging for both μPAD characterization and for quantification of the transport of applied reagents and analytes within these devices. We evaluated the transport of nanoscale particles within μPADs using a suite of differentially functionalized gold (AuNP) and silver (AgNP) nanoparticles with diameters of 8-64 nm. Nanoparticle transport within the cellulose matrix was characterized by collection of both Raman and surface-enhanced Raman spectroscopy (SERS) spectral maps that enabled differentiation of cellulose fibers and characterization of analyte deposition patterns. The transport of citrate (cit), BSA, PEG, PVP, and DNA functionalized AuNP and AgNP in wax-printed μPADs was primarily affected by nanoparticle surface chemistry rather than particle size or core composition. Sample pH (3-10) influenced the transport of 15 nm BSA-cit-AuNP, but not 15 nm cit-AuNP, because of the effects of solution pH on the charge and conformation of BSA. Derjaguin, Landau, Verwey, and Overbeek theory (DLVO) and extended DLVO (xDLVO) theory are used to explain the collected experimental results.Its a Pop figurine of my favorite Game of Thrones character. Daenerys Targaryen everybody!!!!! And I also got a gift card to Chipotle! Thank you so much.Jackson Joshua, 14 Mar 2013Whats saddening is that Samsung needs an overclocked 8 core processor & 2 GB RAM to beat a... morethat's very true and it clearly shows the amount of 'innovation' at Samsung. Bigger in some cases is definetly not better. Can some advice, all feature they shows are of S4 or they are in S4 because of Jelly Bean 4.2.2 I am using Note2 if these features of OS than I'll automatically get this when I get an update....... Thanks in advance... Azady, 14 Mar 2013despite i hate the design, but there is no more option for me to choose either this or htc one... moreit just lunched the design is slightly different from the alleged phone published, if you look at front cam u will notice the cam lens are bigger, the design is actually nice, it has great features, will buy it for sure i am watching it right now go to youtube write 'Samsung UNPACKED 2013 Livestream' to watch it live. The best phone? Its a joke? This is the same phone -.- than note 2 or S3 -.- same design, same quality -.- this is not funny. Xperia Z or Optimus G or HTC One are better than this phone and the 8 cores not faster than Qualcomm SnapDragonS4 pro or Qualcomm 800. ThomasCarlsson, 14 Mar 2013Android is more or less dead because Google have removed Adaway and Adfree Android and Adblock... moreYou can get all that from xda-developers. Their host file to prevent ads is actually helluva lot better, too.Main menu Tag Archives: ornithologist Someone(s) once commented that Pete Dunn is a writer who birds, while Kenn Kaufman is a birder who writes. (Both of these men are well known in the birding community and have published countless books each.) I am in no means a writer. Or at least I don’t consider myself to be one. However, I think that if you substitute writer with educator, this phrasing might work for me. Thus, Jordan is a birder who educates, not the other way around. JER giving a bird banding demonstration to a kindergarten class in Texas I bring this up because several people (all of whom don’t know each other) have brought up the idea/suggestion that I be a teacher. While that’s always been an option and kept on the back burner list of possibilities, I just don’t see it being the vocation I make my life’s career out of. Being a teacher isn’t the job that I feel compelled to rush out and sign up for. Being a bird educator/outreacher of some kind though, that is something I can day dream about. Why dismiss a traditional teaching position so quickly when it comes up? Well, to be honest, there aren’t any birds…or at least not enough. Yes, there are programs (some of which I’ve worked for and am connected with) that can be brought into the classroom. Yes, there are lesson plans and curriculum involving birds and bird information. But for me, that’s not enough. Why not just be an ornithologist then? This situation is the complete opposite of teaching though. Where are the people to share the bird information with? Where is the opportunity to talk and engage with people from other backgrounds to get new perspectives and always push me/us to be the best, most scientific ornithologist as possible? Where is the ability to be continually re-energized by the excitement and questions and wonder seen in other people that are being exposed to birds and bird research. A summer job I once had seems like a great match then. (I put on educational bird events for kids.) Here’s the only thing, the constant change in kids was basically the only thing that made it new and exciting. We had a set program that we did…every, single time. To be honest, after a while it started to get a little repetitive for me. The issue I see with doing something that involves so much repetition is that I fear I might lose some of my enthusiasm or spark. This is why I need the balance of both worlds. What I may lack in terms of formal education background or training (as of now), I make up with passion. The research aspect keeps me learning and giving me the ability to always have new material to share with others. The outreach component gives me the opportunity to feel like I’m making a difference and doing my part for science and the environmental movement. How do I describe the balance of ornithology and education/outreach? Liaison. That is what I want to be. I don’t know how else to describe it. I want to take the science and ornithological research and translate that for everyone else to understand. I’m finding it very difficult to do this though. With the way things are today, it seems as though the choice is either classroom or lab. I’m not happy settling with only those two options. This all probably sounds stubborn or greedy, but if I’m going to follow what I’ve been taught and stressed by countless people over my life, then I need to “love what I do and do what I love.” And birds and talking about birds is what I love.Q: R: Column Heading Conversions I have the following dataset. My objective is to understand how numbers and mammals and birds are there in the two types of locations. df1: Location Type Cat Mouse Dog Chicken Turkey Horse 1 1 0 0 1 0 1 1 0 0 1 0 1 0 2 1 1 1 1 1 1 2 0 1 0 0 0 0 1 1 1 0 0 1 0 I want it to read as df2: Location Type M M M B B M 1 1 0 0 1 0 1 1 0 0 1 0 1 0 2 1 1 1 1 1 1 2 0 1 0 0 0 0 1 1 1 0 0 1 0 with 'M' denoting Mammal and 'B' denoting Bird I tried to manually enter the data into my.csv file and use it in R, however, the file gets read as df2: Location Type M M1 M2 B B1 M3 1 1 0 0 1 0 1 1 0 0 1 0 1 0 2 1 1 1 1 1 1 2 0 1 0 0 0 0 1 1 1 0 0 1 0 I am not sure why each 'M' or 'B' column gets numbered separately, how could I prevent this from happening or I also have the animal type classified as mammal and bird in another dataframe as below dfanimal: Name of Animal Mammal/Bird Cat Mammal Dog Mammal Mouse Mammal Chicken Bird Turkey Bird Horse Mammal If there is a way for me to directly work my way with the dataframes, df1 and dfanimal? Would be very thankful for any help. A: After you manually change the column names, you can use check.names = FALSE while importing the
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2991, 1408, 1082, 551, 187, 50258, 24951, 8207, 15, 1178, 26998, 9, 5672, 558, 187, 50259, 605, 4780, 8207, 15, 1178, 25155, 1490, 18, 15, 17, 558, 187, 50262, 94, 187, 50266, 9897, 535, 50270, 94, 187, 50274, 94, 187, 187, 34 ]	start of the compressed data. / start_byte = page_offset(bvec.bv_page) - disk_start; / we haven't yet hit data corresponding to this page / if (total_out <= start_byte) return 1; / * the start of the data we care about is offset into * the middle of our working buffer / if (total_out > start_byte && buf_start < start_byte) { buf_offset = start_byte - buf_start; working_bytes -= buf_offset; } else { buf_offset = 0; } current_buf_start = buf_start; / copy bytes from the working buffer into the pages / while (working_bytes > 0) { bytes = min_t(unsigned long, bvec.bv_len, PAGE_SIZE - buf_offset); bytes = min(bytes, working_bytes); kaddr = kmap_atomic(bvec.bv_page); memcpy(kaddr + bvec.bv_offset, buf + buf_offset, bytes); kunmap_atomic(kaddr); flush_dcache_page(bvec.bv_page); buf_offset += bytes; working_bytes -= bytes; current_buf_start += bytes; / check if we need to pick another page / bio_advance(bio, bytes); if (!bio->bi_iter.bi_size) return 0; bvec = bio_iter_iovec(bio, bio->bi_iter); prev_start_byte = start_byte; start_byte = page_offset(bvec.bv_page) - disk_start; / * We need to make sure we're only adjusting * our offset into compression working buffer when * we're switching pages. Otherwise we can incorrectly * keep copying when we were actually done. / if (start_byte!= prev_start_byte) { / * make sure our new page is covered by this * working buffer / if (total_out <= start_byte) return 1; / * the next page in the biovec might not be adjacent * to the last page, but it might still be found * inside this working buffer. bump our offset pointer / if (total_out > start_byte && current_buf_start < start_byte) { buf_offset = start_byte - buf_start; working_bytes = total_out - start_byte; current_buf_start = buf_start + buf_offset; } } } return 1; } Q: Save file with Russian letters in the file name I have this Python script that takes the info of a webpage and then saves this info to a text file. But the name of this text file changes from time to time and it can changes to Cyrillic letters sometimes, and some times Korean letters. The problem is that say I'm trying to save the file with the name "бореиская" then the name will appear very weird when I'm viewing it in Windows. I'm guessing I need to change some encoding at some places. But the name is being sent to the open() function: server = "бореиская" file = open("eu_" + server + ".lua", "w") I am, earlier on, taking the server variable from an array that already has all the names in it. But as previously mentioned, in Windows, the names appear with some very weird characters. A: tl;dr Always use Unicode strings for file names and paths. E.g.: io.open(u"myfile€.txt") os.listdir(u"mycrazydirß") In your case: server = u"бореиская" file = open(u"eu_" + server + ".lua", "w") I assume server will come from another location, so you will need to ensure that it's decoded to a Unicode string correctly. See io.open(). Explanation Windows Windows stores filenames using UTF-16. The Windows i/o API and Python hides this detail but requires Unicode strings, else a string will have to use the correct 8bit codepage. Linux Filenames can be made from any byte string, in any encoding, as long as it's not ASCII "." or "..". As each system user can have their own encoding, you really can't guarantee the encoding one user used is the same as another. The locale is used to configure each user's environment. The user's terminal encoding also needs to match the encoding for consistency. The best that can be hoped is that a user hasn't changed their locale and all applications are using the same locale. For example, the default locale may be: en_GB.UTF-8, meaning the encoding of files and filenames should be UTF-8. When Python encounters a Unicode filename, it will use the user's locale to decode/encode filenames. An encoded string will be passed directly to the kernel, meaning you may get lucky with using "UTF-8" filenames. OS X OS X's filenames are always UTF-8 encoded, regardless of the user's locale. Therefore, a filename should be a Unicode string, but may be encoded in the user's locale and will be translated. As most user's locales are .UTF-8, this means you can actually pass a UTF-8 encoded string or a Unicode string. Roundup For best cross-platform compatibility, always use Unicode strings as in most cases they will be translated to the correct encoding. It's really just Linux that has the most ambiguity, as some applications may choose to ignore the default locale or a user may have changed their locale to a non-UTF-8 version. Q: ProgressIndicator freezes when button is pressed. JavaFX I'm using a indicator progress set to -1.0 to show some loading while loginprocess is running. But when I press the Enter button and start my executor with the loginProcess, my interface stays freezed even if I use Plataform.runLater to set visible my ProgressIndicator. My button event: public void initManager(final LoginManager loginManager) { btnEntrar.setOnAction(new EventHandler<ActionEvent>() { @Override public void handle(ActionEvent event) { String email = loginTxtField.getText().trim(); String token = tokenTxtField.getText().trim(); if (email.equals("")) { Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", "Digite o e-mail"); } }); return; } try { Future future = loginProcess(email, token); showLoginLoading(future); future.get(); if (!loginGatewayFailed &&!loginTargetAppFailed) { Login loginTargetApp = new Login(email, null, null); loginManager.autheticated(loginTargetApp, loginGateway, gateway, file); } else { if (loginTargetAppFailed) { Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", loginTargetAppFailedCause); } }); } else { if (loginGatewayFailed) { Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", loginGatewayFailedCause); } }); } } } } catch (final Exception ex) { Logger.getLogger(LoginController.class.getName()).log(Level.SEVERE, ex.getMessage()); Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", ex.getMessage()); } }); } } }); } My loginProcess: public Future<?> loginProcess(String email, String token) throws Exception { // MY PROCESS return Executors.newSingleThreadExecutor().submit(new LoginTask(this, email, token)); } catch (Exception e) { Logger.getLogger(LoginController.class.getName()).log(Level.SEVERE, e.getMessage()); throw e; } } method showLoginLoading: private void showLoginLoading(Future future) { while (!future.isDone()) { Platform.runLater(new Runnable() { @Override public void run() { progressInd.setVisible(true); // progressInd.setProgress(-1.0); } }); } } A
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I need it to work the same way as the homepage. And a way to change them if I need to. Should be very easy to do as you can already do o...<?xml version="1.0" encoding="UTF-8"?> <project version="4"> <component name="ProjectModuleManager"> <modules> <module fileurl="file://$PROJECT_DIR$/app/app.iml" filepath="$PROJECT_DIR$/app/app.iml" /> <module fileurl="file://$PROJECT_DIR$/seekbar.iml" filepath="$PROJECT_DIR$/seekbar.iml" /> </modules> </component> </project>![](envhper00434-0104.tif "scanned-page"){.109} ![](envhper00434-0105.tif "scanned-page"){.110} ![](envhper00434-0106.tif "scanned-page"){.111} ![](envhper00434-0107.tif "scanned-page"){.112} ![](envhper00434-0108.tif "scanned-page"){.113} ![](envhper00434-0109.tif "scanned-page"){.114} ![](envhper00434-0110.tif "scanned-page"){.115} ![](envhper00434-0111.tif "scanned-page"){.116} ![](envhper00434-0112.tif "scanned-page"){.117} ![](envhper00434-0113.tif "scanned-page"){.118} ![](envhper00434-0114.tif "scanned-page"){.119} Parasailing Old Orchard Beach Parasailing with Old Orchard Beach Parasailing & Jet Ski will be the Highlight of your trip. The waters off of Old Orchard Beach will be the starting point for your aerial adventure, culminating in an unbelievable view from high above the waters of Old Orchard Beach. You will float effortlessly from our parasail canopy as you soar along with the gulls and frigates, peering down into the water. From your lofty perch, you will be able to take in the fabulous view of Old Orchard Beach providing you with an unparalleled visual experience. How it works: Old Orchard Beach Parasailing utilizes the newest technology and systems to provide anyone with a safe, soft, controlled parasailing experience. Our state of the art vessel is built solely for your parasailing enjoyment. Up to six people can go out on the boat for the excursion. You and up to three of your friends or family members can ride in the parasail together and share the moment–from a seated position on the back deck you will feel the boat pull away as you almost imperceptibly lift up into the air. The Kevlar towline is reeled out from a winch so smoothly that it feels as if the boat simply leaves you while your view becomes increasingly more beautiful as you climb higher and higher, leaving the gravity-bound world below. For the more adventurous, we can provide an incredible experience we call a ”free fall” where the captain slows the boat and lets you float down with the parachute until you almost touch the water, then he hits the throttle and up you come again! Of course, we can add a little "splash" as well, for those of you who prefer to cool off before returning to the deck. Everyone lands softly back onto the deck as the captain reels the line back in, compelling the parachute to return to the boat every time. By the way, our captains are US Coast Guard certified and have years of parasailing experience. 10 So.3d 722 (2009) Sonja JAMES, et al. v. STATE FARM MUTUAL AUTOMOBILE INSURANCE COMPANY, et al. No. 2009-CC-0967. Supreme Court of Louisiana. June 19, 2009. Granted. The case is remanded to the trial court for reconsideration of its ruling *723 in light of Gingles v. Dardenne, 08-2995 (La.3/13/09), 4 So.3d 799. KIMBALL, C.J., would deny the writ. JOHNSON, J., would deny the writ. KNOLL, J., would deny the writ. Indiana Mom Strikes Plea Deal In Child Neglect Case An Indiana mother has reached a plea deal with prosecutors in a child neglect case involving three of her severely malnourished children and her 14-month-old daughter who sustained a skull fracture. Sheena A. Zanghi, 24, was charged Monday with four counts of neglect of a dependent, a charge that could bring up to three years in prison. Details on the plea agreement were not released, with Henry Circuit Court 1 Judge Mary Willis setting sentencing for the tentative date of Aug. 13. Although Zanghi reached a plea deal with prosecutors back in February, a judge rejected the agreement in April, according to WTHR. ADVERTISEMENT Thanks for watching! Zanghi and her four children were discovered by police in June 2014 living in a mobile home with no running water, electricity or a functioning bathroom, according to the Muncie Star Press. Vincent Zanghi, Sheena's 36-year-old husband, also lived with them. Sheena's 81-year-old grandfather, Earl Lee Larue, who ran the nearby trailer supplying some electricity to his granddaughter's trailer, told police that Vincent assaulted him, and that he was likely abusing the children, too, according to The Inquisitr. The officers who arrived at the scene recall seeing broken glass, wood and nails outside the home--easily accessible to the children. They also remember smelling urine before entering the home, WXIN reported. ADVERTISEMENT Thanks for watching! ADVERTISEMENT Thanks for watching! All four children had cuts and bruises over their bodies, which were reportedly caused by the pit bull puppies Zanghi owned. The three youngest children were so malnourished that they exhibited "poor linear and brain growth", placing them at risk for developmental delays. A child abuse specialist was also concerned that at least one of Zanghi's children had suffered from physical abuse.20 Board Games Based on ’70s and ’80s TV Shows Better than trading cards, less useful than a lunchbox, and perfect for weekend collecting, there are a staggering number of board games based on classic television shows from the ‘70s and ‘80s still knocking around. Here are 20 of the very best. 1. Happy Days An almost totally Fonzie-focused endeavor, the entire aim of the Happy Days game is to collect enough “cool points” to impress the Fonz. Along the way, points are tallied by lighting up Arnold’s jukebox and time passes by finding “sumthin’ to do.” 2. Cheers How’s your Cheers knowledge pool? Not too deep? Don’t worry, you can almost wing it with this trivia-based game—if you pay enough attention to hints about how the various bar occupants acted on the show, which pepper gameplay. Watch out for “Normie’s Olympics,” though, a mini-game that uses the sort of skills that only a drunk dude could master (it involves both balance and total carelessness). 3. Barney Miller The Barney Miller board game has a few surprises up its cardboard sleeves—no one gets to play the eponymous cop and it’s essentially a bettor’s version of the match game. Is this how cops actually do their job? Perhaps—at least on television. 4. Knight Rider This “high speed adventure game” doesn’t come with a tiny David Hasselhoff cutout, but it does require players to travel an admittedly “never-ending road” without getting hijacked. Clear “Trouble Spots” and hope that your robot car doesn’t get stolen—something you’d think K.I.T.T. would be far too clever to allow anyway. 6. The A Team We pity the fool who doesn’t feel instantly compelled to play the board game version of The A Team once they hear what it’s about. Curiously focused on a mission to retrieve a stolen soda recipe from an evil band of apparently very weird baddies, the goofy action of the classic show is in full effect in this one-dimensional quest. 7. Welcome Back, Kotter Intent on capitalizing on its trademark “up your nose with a rubber hose” tagline, the Welcome Back, Kotter game is entirely centered on said hose. The aim of the game is to use cards to spell out the entire phrase, and the “winner” ultimately gets a small piece of, you guessed it, rubber hose to celebrate their victory. 8. CHiPS It would be pretty unsafe to attempt to replicate the highway hijinks of CHiPS the show, so this board game will have to suffice. Each player takes on the role of a motorcycle cop, bound for the sort of glory that will only come after capturing no less than four vehicular b
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394, 14, 9888, 5685, 30525, 40, 757, 33986, 66, 19523, 4611, 187, 187, 40, 757, 33986, 66, 19523, 4611, 313, 6448, 9847, 4534, 80, 13, 1638, 2552, 16648, 10, 310, 271, 9890, 23721, 13, 16518, 13, 22531, 285, 18468, 665, 310, 6571, 1929, 347, 253, 2022, 1963, 9141, 273, 253, 49562, 285, 3909, 48386, 757, 14275, 26479, 13, 534, 2335, 1659, 275, 3919, 4059, 15, 187, 187, 1909, 247, 9835, 5974, 273, 17388, 387, 253, 2499, 273, 20254, 5738, 13, 19523, 4611, 7416, 418, 16405, 12683, 1464, 1253, 45, 3604, 23060, 285, 369, 10544, 21209, 46395, 263, 275, 12000, 1321, 15, 14566, 644, 39372, 432, 326, 3128, 13, 344, 369, 581, 273, 253, 23569, 2758, 273, 253, 20254, 44316, 20911, 382, 25678, 275, 8210, 285, 369, 697, 28179, 323, 767, 1107, 15, 496, 436, 5350, 13, 344, 369, 13084, 323, 1907, 644, 271, 562, 33065, 31409, 273, 20254, 16642, 285, 273, 253, 48386, 757, 5595, 1023, 9457, 7295, 434, 21935, 273, 659, 15, 4744, 434, 8647, 266, 587, 275, 28792, 15, 831, 1390, 2362, 3977, 19523, 4611, 281, 9488, 521, 2393, 20254, 266, 382, 10450, 285, 281, 29534, 281, 253, 48386, 757, 14275, 4866, 15, 187, 187, 7130, 281, 521, 1211, 3000, 13, 19523, 4611, 4895, 281, 3939, 8672, 760, 846, 253, 1305, 257, 267, 5837, 273, 346, 7083, 1022, 273, 4743, 3446, 496, 5403, 344, 4159, 247, 41985, 1059, 327, 14275, 285, 369, 247, 23569, 3558, 273, 253, 48386, 2458, 25678, 285, 13, 247, 807, 1996, 13, 344, 10098, 253, 48845, 285, 1323, 12997, 314, 2533, 255, 382, 48386, 757, 3313, 7021, 313, 15332, 55, 582, 285, 5608, 347, 697, 3872, 14385, 432, 4695, 281, 4267, 15, 754, 369, 1996, 3939, 13, 2223, 3192, 9550, 9503, 13, 275, 247, 27262, 273, 2533, 255, 382, 46881, 13, 512, 13082, 432, 10713, 273, 253, 367, 23459, 27, 12683, 16713, 2418, 313, 7199, 1253, 6755, 582, 48386, 757, 32237, 313, 6755, 1253, 6622, 582, 21231, 67, 2865, 614, 4072, 313, 6622, 1253, 6759, 10, 285, 13, 4720, 13, 12683, 16713, 6279, 313, 17480, 4072, 481, 187, 187, 688, 4059, 19523, 4611, 2210, 281, 9933, 44373, 347, 253, 2022, 1963, 9141, 273, 21231, 67, 2865, 7067, 15, 16427, 13, 271, 3909, 26479, 327, 12683, 16713, 434, 14275, 15, 4794, 281, 253, 4750, 13, 374, 15, 1812, 3041, 48386, 2458, 313, 3571, 15, 19, 6, 273, 512, 13410, 11163, 10, 13640, 275, 253, 3909, 26479, 285, 11289, 15, 18, 6, 273, 731, 313, 3529, 310, 281, 1333, 8026, 15, 23, 6, 273, 512, 13410, 11163, 10, 14285, 4754, 15, 831, 369, 2217, 323, 19523, 4611, 285, 521, 18409, 281, 354, 7041, 12683, 16713, 434, 14275, 432, 9972, 275, 9847, 4534, 80, 327, 253, 2360, 273, 3127, 3919, 15, 496, 253, 8461, 13, 3578, 346, 615, 1851, 684, 323, 14275, 3, 497, 10544, 1512, 27, 19523, 4611, 369, 253, 954, 14285, 7431, 342, 13620, 13, 18950, 14682, 13008, 15, 187, 187, 1328, 556, 4102, 5485, 247, 23978, 2567, 275, 43372, 571, 13, 4907, 3035, 76, 1406, 375, 13, 25251, 2067, 50150, 84, 1580, 4765, 15, 1583, 1750, 281, 452, 5728, 1249, 3041, 8918, 13, 1097, 432, 48386, 757, 952, 285, 643, 946, 28457, 15, 187, 187, 4941, 187, 187, 1413, 27, 25892, 10782, 187, 1413, 27, 14316, 952, 187, 1413, 27, 39685, 292, 757, 13557, 187, 1413, 27, 39685, 292, 382, 13557, 187, 1413, 27, 8836, 432, 9847, 4534, 80, 187, 1413, 27, 938, 394, 14, 9888, 9890, 13557, 187, 1413, 27, 1797, 296, 14, 9888, 9890, 13557, 2042, 368, 4288, 407, 2329, 390, 3297, 275, 21440, 1309, 634, 9836, 8729, 24779, 13, 368, 403, 417, 247, 6867, 5396, 22777, 15, 380, 1685, 310, 253, 954, 1846, 4438, 273, 4616, 285, 625, 952, 3297, 342, 3858, 285, 17772, 1309, 824, 19055, 685, 275, 21440, 285, 12141, 9910, 13, 2556, 281, 247, 3313, 24046, 17136, 44115, 313, 47, 3528, 48, 10, 1304, 15, 6037, 4288, 310, 2761, 22879, 15, 187, 187, 2773, 753, 13, 954, 952, 403, 9100, 625, 327, 4288, 685, 597, 858, 253, 1390, 673, 824, 271, 5763, 369, 4824, 562, 275, 4695, 14, 2693, 15, 187, 187, 1276, 4850, 16869, 22710, 32, 187, 187, 510, 427, 3528, 48, 6630, 13, 534, 369, 4824, 562, 275, 4059, 14, 1010, 13, 556, 767, 9351, 273, 6128, 327, 253, 4283, 4096, 273, 247, 7408, 1128, 783, 1921, 1293, 534, 253, 7408, 812, 417, 452, 644, 20023, 15, 187, 187, 6436, 13, 627, 310, 247, 3064, 275, 253, 5133, 275, 534, 6128, 452, 644, 5728, 323, 1027, 6378, 15, 1198, 13319, 272, 13, 27335, 285, 37481, 28, 1786, 285, 3739, 26742, 28, 285, 12701, 13, 247, 6983, 2180, 273, 23412, 1897, 556, 644, 2668, 15, 1198, 2136, 28, 2675, 28, 7231, 285, 31514, 13485, 28, 4730, 285, 3733, 285, 773, 39658, 995, 247, 1884, 14, 1201, 6983, 2180, 556, 644, 2668, 15, 10300, 253, 3064, 275, 16182, 13, 253, 767, 2550, 320, 2429, 15, 3813, 13, 359, 30648, 253, 3894, 273, 19055, 407, 4283, 4096, 327, 253, 3720, 273, 253, 6983, 2180, 908, 15, 187, 187, 688, 1097, 9050, 13, 670, 581, 275, 2620, 18294, 2361, 1907, 4783, 327, 387, 1878, 581, 13463, 7408, 15, 187, 187, 688, 253, 23412, 14, 1201, 7140, 13, 773, 15356, 285, 3739, 3, 369, 253, 4283, 4096, 273, 253, 7408, 275, 1097, 11393, 285, 10106, 3672, 13, 15890, 323, 3387, 6, 273, 512, 4288, 15, 733, 369, 3560, 407, 27335, 2425, 313, 1671, 10970, 496, 253, 1884, 14, 1201, 6983, 2180, 13, 2675, 12941, 403, 253, 4283, 4096, 273, 247, 7408, 13, 15890, 323, 247, 7863, 11614, 15, 23, 6, 273, 512, 4288, 15, 187, 187, 21166, 670, 19055, 323, 2136, 13, 2675, 4606, 13, 7231, 13, 11331, 390, 643, 6378, 369, 13037, 342, 247, 1884, 14, 1201, 673, 2180, 275, 2564, 15, 8404, 19055, 20184, 323, 11422, 15, 19, 6, 273, 19055, 1160, 689, 253, 1390, 1884, 1897, 275, 11393, 3672, 285, 11439, 15, 18, 6, 275, 10106, 3672, 15, 187, 187, 34, 5301, 281, 247, 2074, 6630, 4824, 562, 275, 4695, 14, 2693, 2722, 326, 253, 2408, 273, 2583, 5262, 556, 2559, 3012, 323, 512, 9351, 273, 19055, 15, 380, 5962, 6054, 556, 644, 323, 12701, 19055, 387, 31389, 5294, 3560, 407, 1786, 285, 3739, 26742, 313, 20922, 10970, 187, 187, 510, 954, 3939, 1375, 275, 2426, 273, 26742, 310, 47766, 15, 36388, 581, 275, 767, 18294, 313, 16576, 5693, 15, 23, 2673, 275, 326, 1375, 2361, 13463, 19055, 275, 253, 1390, 23412, 1897, 390, 253, 1390, 1884, 1897, 1078, 253, 6630, 15, 733, 369, 3560, 407, 15101, 607, 267, 35112, 313, 2385, 2673, 285, 15315, 1906, 285, 35416, 313, 2504, 15, 25, 10970, 187, 187, 2512, 310, 247, 19143, 6891, 8037, 875, 10106, 285, 11393, 5427, 672, 352, 3249, 281, 9836, 26742, 15, 187, 187, 2512, 369, 642, 3064, 387, 271, 512, 14, 31870, 1268, 275, 253, 2408, 273, 22710, 2218, 407, 11393, 285, 10106, 18294, 13, 253, 1304, 753, 15, 733, 4879, 326, 1097, 497, 4503, 275, 2426, 273, 9610, 387, 1878, 581, 13463, 7408, 689, 253, 2045, 807, 323, 6378, 534, 2908, 27335, 13, 16280, 1786, 14, 4919, 19055, 285, 12701, 16625, 4431, 15, 187, 187, 2512, 497, 690, 1375, 14, 5251, 3910, 15, 496, 2903, 312, 285, 500, 73, 782, 4608, 13, 627, 369, 625, 22710, 2361, 275, 253, 10106, 13779, 685, 275, 11393, 4811, 15, 496, 643, 3054, 824, 347, 12828, 31210, 49604, 285, 1244, 73, 376, 35112, 13, 952, 275, 11393, 3672, 29433, 625, 15, 187, 187, 3039, 597, 513, 4288, 13, 253, 1685, 310, 253, 954, 1846, 4438, 273, 4616, 323, 5427, 457, 84, 9836, 24359, 15, 831, 310, 2032, 275, 1097, 11393, 285, 10106, 3672, 15, 733, 8553, 323, 5922, 15, 22, 6, 273, 4288, 275, 10106, 3672, 285, 7584, 15, 26, 6, 275, 11393, 3672, 15, 6572, 968, 285, 14565, 4616, 403, 253, 767, 643, 2201, 10006, 273, 4616, 275, 1097, 3672, 15, 6037, 4288, 310, 3710, 281, 337, 15, 26, 6, 323, 10106, 285, 470, 15, 18, 6, 323, 11393, 4288, 15, 187, 187, 53, 3385, 20945, 3297, 2080, 625, 342, 3858, 285, 17772, 685, 387, 21440, 285, 12141, 9910, 15, 9240, 432, 10106, 3672, 403, 625, 2779, 281, 3297, 275, 21440, 15, 380, 773, 39658, 3, 7140, 275, 3797, 18217, 10988, 13, 6179, 9956, 13, 1786, 25543, 13, 15929, 9076, 1128, 9154, 40667, 15, 187, 187, 510, 30505, 2238, 273, 19055, 403, 1110, 323, 12701, 15, 1583, 3839, 1390, 767, 281, 1264, 15513, 15, 8057, 254, 4394, 403, 1110, 9355, 347, 27335, 19055, 285, 1390, 1740, 1897, 390, 625, 15, 380, 1304, 4879, 326, 12701, 19055, 4592, 275, 253, 8986, 15, 41079, 19055, 285, 31514, 13485, 3053, 275, 4163, 285, 4223, 15, 187, 187, 1145, 4722, 4560, 275, 253, 6630, 310, 253, 6054, 273, 253, 2014, 5343, 11074, 7707, 15, 418, 531, 2255, 43817, 2395, 323, 247, 1534, 8394, 273, 952, 22710, 3815, 15, 1244, 627, 310, 19143, 1652, 10106, 14, 83, 1546, 8037, 2190, 824, 43817, 15, 1310, 253, 1180, 273, 2255, 22710, 3815, 8553, 323, 4562, 6, 273, 512, 33178, 10106, 43817, 13, 253, 3969, 1180, 323, 11393, 3672, 310, 1884, 7739, 1244, 253, 8394, 273, 2255, 22710, 3815, 323, 12701, 310, 2169, 275, 11393, 5427, 15, 41079, 4288, 390, 31514, 13485, 285, 2675, 4288, 671, 923, 625, 33178, 2255, 43817, 347, 247, 8394, 273, 2264, 33178, 43817, 275, 253, 11393, 8223, 15, 187, 187, 35638, 281, 41598, 6317, 29076, 475, 10871, 247, 3588, 4579, 475, 11239, 368, 323, 20404, 272, 281, 776, 25144, 15, 187, 187, 18281, 29482, 47, 3178, 20290, 23247, 10035, 11578, 5292, 285, 24336, 26853, 1481, 598, 247, 4836, 3490, 15686, 253, 2685, 273, 10038, 296, 7077, 715, 16146, 15, 7160, 3186, 5644, 281, 247, 8312, 6963, 9852, 13, 3692, 2098, 281, 1453, 253, 2846, 434, 2854, 7137, 556, 14435, 745, 271, 19076, 2137, 15, 16257, 13, 1841, 755, 25594, 875, 10035, 285, 16739, 13, 24336, 434, 7586, 15, 29569, 16681, 322, 1831, 18535, 5536, 29923, 38700, 1131, 285, 5145, 5654, 3289, 3735, 2822, 34370, 484, 311, 187, 187, 30641, 375, 864, 7381, 285, 22404, 2312, 670, 17749, 492, 6977, 34756, 13, 20510, 375, 864, 7381, 434, 3906, 2296, 187, 187, 37881, 588, 3794, 604, 747, 8215, 17634, 403 ]	1966. Kärnter Exilantenschicksal in der Zeit der Gegenreformation – ein Beitrag zur Geschichte der religiös motivierten Vertreibungspolitik Erzherzog Ferdinand II. in Kärnten in den Jahren 1596-1637. Yearbook of the history about the Protestantism in Austria, Jg. 112, Wien, 1996. Michaelis, Hans-Thorald, Das erste deutsche Bundesschießen 1862 in Frankfurt am Main – eine deutsche Tragödie des Unbewältigten, in: Innsbrucker Historische Studien 16/17 (1997), S. 361-406 Geschichte der Familie von Boehmer in Fortführung der von Hugo Erich von Boehmer im Jahre 1982 verfassten Genealogie der von Justus Henning Boehmer abstammenden Familien sowie einiger der mit ihnen verschwägerten Familien. Rheinische Verlagsanstalt, Bad Godesberg, 1978, 248 S.; heading in Library of Congress. Different genealogical publications for the journal „Genealogie“, and also for „Ostdeutsche, Norddeutsche und Mitteldeutsche Familienkunde“ of Degener-Verlag, 91610 Insingen. Hans-Thorald Michaelis works in the catalogue from the German National Library References Category:1925 births Category:2004 deaths Category:German genealogists Category:German male non-fiction writers Category:20th-century German historiansGianluca Busato Gianluca Busato (born Treviso, 14 May 1969) is an Italian entrepreneur, engineer, activist and politician who is mostly known as the main organiser of the unofficial and online Venetian independence referendum, which took place in March 2014. As a university student of Engineering at the University of Padua, Busato joined Liga Veneta–Lega Nord and was elected municipal councillor in Casier. Having been expelled from that party, he was one of the founding members of the Padanian Independentist Movement in 1997 and was its spokesperson for two years. In this capacity, he was convicted for having been an outspoken supporter of Padania and of the Venetian Most Serene Government's seizure of St. Mark's Campanile in Venice. This last event led Busato to abandon his early Padanist feelings and to adhere to the Venetian independence movement. According to his own words, Busato returned to active politics only after the depenalisation of "crimes of opinion". In 2006 he wrote a pamphlet on independence and was a founding member of the Venetians Movement and, a year later, he launched the libertarian and avowedly separatist Venetian National Party (PNV), and served as its national secretary from 2008 to 2010. He was later active, often taking leadership roles, in a succession of separatist outfits, all emerged from bulk of the PNV: Veneto State (2010–2012), Venetian Independence (2012–2013), Plebiscite 2013 (2013–2014) and, finally, Veneto Yes (since 2013). In 2014 Busato came to regional prominence as the main organiser of Plebiscito.eu, an online referendum on Veneto's independence. According to the staff, 2.36 million Venetians (63.2% of all eligible voters) participated in the online referendum and 89.1% of them (that is to say 56.6% of all eligible voters) voted yes. This was enough for Busato and his followers to proclaim Veneto's independence from Italy in Treviso on the night of 21 March. In the poll, ten "delegates for independence" were elected too: Busato was the most voted candidate with 135,306 preference votes. He has recently opened a crypto company in Slovenia, named Enkronos, launching several ICOs since 2018. They claim to have collected 12 million dollars, both from Venetian people and other speculators. References Category:1969 births Category:Living people Category:Venetian politicians Category:Venetist politicians Category:People from Treviso Category:20th-century Italian politicians Category:21st-century Italian politiciansIf you travel by air or stay in hotels during your domestic jaunts, you are not a typical Indian tourist. The bus is the most common mode of transport and more people stay with friends and relatives during such trips than in hotels and guest houses, according to a National Sample Survey Organisation (NSSO) report. Air travel is almost negligible. That said, most people are spending more on travel than they did the last time such an exercise was carried out in 2008-09. What gets Indians travelling? The NSSO survey, which was carried out in 2014-15, has two kinds of responses on the leading purpose of a trip—the reason without which the trip could not have been undertaken. However, there is a difference in the manner in which responses have been collected for different purposes. For holidaying, leisure and recreation; health and medical tourism; and shopping, a recall period of 365 days has been taken. For business; social; religious and pilgrimages; education and training and “others", a 30-day recall period has been taken. Given the difference in methodology, the two cannot be compared. Therefore, we analyse the share of trips by leading purpose on the basis of the recall period used. In both categories, about one in five households reported having gone on at least one overnight trip. In the 365-day category, “health and medical" was the leading purpose of the trip in both rural and urban areas, accounting for 40% of all travel. It was followed by leisure activity (35%). In the 30-day recall period, social visits are the leading purpose of a trip, accounting for a massive 86.6% of all travel. Information about trips for business, social reasons, religious, educational or other purposes was gathered with a 30-day time period in mind. Social trips accounted for 87.2% of trips made over the last 30 days in rural areas and 83.1% in urban areas. A comparison to a similar survey carried out in 2008-09 shows that the amount of money spent has increased significantly for all kinds of trips. The biggest rise has been for shopping trips at 313%, followed by health and medical tourism (291%). The most active state in terms of tourism is Kerala. Nearly one in two households (around 48.6%) in that state reported overnight trips in the last 365 days or the last 30 days before the survey. It was followed by Himachal Pradesh (48%) and Jammu and Kashmir (47.8%). There is a surprisingly narrow gap between urban and rural India when it comes to domestic tourism. There was no difference at an all-India level in the amount of travelling done by rural and urban households, the report said. It noted that both were equal in terms of reporting at least one overnight trip over the previous year for purposes which included leisure, besides health-related trips and shopping expeditions. There were some state-level differences. In Assam and Jharkhand, there was more travelling reported in the urban belt than in rural regions. In other states such as Maharashtra and Andhra Pradesh, people in rural areas travelled more. When they do travel, the bus is the most common mode of transport for India’s domestic tourists. This is true in both rural and urban areas. It accounts for 33.5% of travel in urban areas and 49.9% in rural areas. Trains and hired transport are the two other major modes of transport in both areas. Air travel is limited to 1.9% for urban and 0.1% for rural travel. Travellers stay far more with friends and relatives than at hotels and guest houses. Those from urban areas are more likely to stay in hotels. The “others" category in includes railway stations, waiting rooms, health clinics, nursing homes—even tents. The shortest kind of trips are those for shopping. They generally last two to three nights. Longer ones are those planned as leisure trips and last four days or more. The report noted that shopping trips happened in the winter. Religious trips and pilgrimages started in July and August. An interesting finding in the survey is the rise of the single female traveller. Lone women travellers account for a significant proportion of people travelling alone. And there is surprisingly little urban-rural gap among such travellers. If the number of women travelling alone accounts for 31% of all lone urban travellers, the corresponding number for rural areas is 30%. And the proportion of women travelling alone for shopping is higher in rural India. Religious travel or pilgrimages and social travel also see more lone women travellers as a proportion of total lone travellers in the rural segment. Subscribe to Mint Newsletters * Enter a valid email * Thank you for subscribing to our newsletter. Share ViaNarcotics cops Mike Lowrey and Marcus Bennett head up a task force investigating the flow of ecstasy into Miami. Their search leads to a dangerous kingpin, whose plan to control the city's drug traffic has touched off an underground war. Meanwhile, things get sexy between Mike and Syd, Marcus's sister.Story highlights Sporadic heavy artillery barrages and machine gun fire heard near Mariupol Poroshenko and Putin talk about ensuring truce lasts, Poroshenko's office says Russia will respond if new EU sanctions are
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After reaching out to over 200 record shops across the country, here it is. Rhubarb Records are proud to bring you our Australian record store directory...Dig in. If we've somehow missed your store or you know of one that we have missed please feel free to contact us via email and we will update this list. We hope this directory will help you discover new Australian Indie Record Stores!Strava! Visit the TD Five Boro Bike Tour route map on Strava to get a detailed, turn-by-turn map of the event. You can even download the route to your Garmin or smartphone. And if you’re looking for training partners or some company on the ride, check out the Bike New York club on Strava. Don’t forget to upload your tour to Strava. All participating Strava cyclists will be entered to win 10 great prizes, like a Fitbit Surge, Strava Premium membership and Greenblender smoothie kit. HOW CAN I EDIT MY TEAM AND REGISTRATION DETAILS?As the world braces for a recession triggered by the coronavirus outbreak, venture capital–backed startups across several industries are making significant cuts to their employee numbers. Four companies have cut roughly 20% of their workforce in an effort to reduce cash burn rates and increase savings—online mattress retailer Eight Sleep, tech-enabled recruiting tool Triplebyte, hospitality startup The Guild, and luxury sleeper-bus service Cabin, according to people familiar with the companies. The number of jobs cut was relatively small—75 people across all four, ranging across both technical and nontechnical job roles—but they’re a harbinger of what is to come. Meanwhile, scooter rental service Lime is reportedly considering job cuts after terminating its operations in most of its markets.A micro-unit housing developer who hoped to build apartments at Fifth and Waller streets is now setting his sights on an East Cesar Chavez property – the site of a proposed Eastside hotel that galvanized neighborhood opposition – to construct the affordable housing complex. In March, real estate developer Taylor Wilson of Centec Management, LLC unveiled plans for Austin's largest micro-housing property: some 260 units averaging 400 square feet, primarily aimed at a low-income demographic. Wilson told the Chronicle that deal recently fell through after a longtime tenant at the site was unable to move out before 2017. But he said he's now close to finalizing terms to buy the property at 1207 E. Cesar Chavez from investors that include Brian and Bree Carrico – the husband-and-wife pair of would-be hoteliers whose proposed project in fast-gentrifying East Austin garnered broad community opposition (see: "East Side Hotel Denied," June 10). Eastside residents balked at the hotel plan, citing the likely increased traffic the proposed 65-room hotel would bring to an already congested East Cesar Chavez, and the city's Planning Commission sided with residents, voting 4-1 against granting a conditional use permit for the hotel. In a recent telephone interview, Carrico acknowledged he was in conversations with Wilson to sell the land; citing ongoing negotiations, he declined to provide more details. But Wilson says the land transfer is something of a foregone conclusion: "We have what I would call a firm handshake agreement to buy the site. We can get that site no problem; that's a done deal." But there's a new snag: Wilson says discussion with the owners of two needed lots in the development's footprint located at 1205 E. Cesar Chavez aren't moving as quickly as the discussions with the Carricos' investment team. Acquisition of those two lots – collectively comprising about one-fourth of an acre – would allow parking entry away from the congested East Cesar Chavez artery as community representatives would prefer, he said. Wilson has been apprising members of the East Cesar Chavez Neighborhood Planning Team for some weeks now on his plans for the land. A changed entry site would add to an already long list of changes from the original plans Wilson had envisioned. The rebooted project will be smaller and contain fewer units. Of the 151 units at 1207 E. Cesar Chavez, 128 would be micro-units – with a mixture of affordable and market-rate apartments – and 23 live/work units designed for owners of small businesses on the ground floor who also would be tenants. The original combination of partners is likely to change as well. And Wilson said the units will be prefabricated modular ones to be later assembled and stacked atop each other, speeding up completion by allowing site work to be performed simultaneously as off-site module construction. "My calculation is that it will save nine months," he said. "It can still be done in a high-caliber manner with tighter, better construction of units in a fraction of the time." Alberto Martinez of the East Cesar Chavez Neighborhood Planning Team – which was stridently opposed to the Carricos' hotel plans – is amenable to Wilson's project. He said the planning team members were appreciative of the approach by Wilson, a 24-year-old entrepreneur following his real estate developer father's footsteps, in communicating his plans with them. "We were very impressed by him," Martinez said in a recent phone interview. "We would welcome" the micro-units project, which would offer much-needed affordable housing for some on the Eastside where property rates have risen in light of commercial development. That tentative endorsement is in marked contrast to opposition to the scrapped hotel plans at that same site of land. "What is happening in East Austin is everyone wants to make as much as they can and the neighborhood be damned," said Martinez. "There's a lack of creativity. But this we would welcome." Even while acknowledging that he's a businessman trying to make a profit off his ventures, Wilson said the idea of building much-needed affordable housing in an area of the city where there is a critical need for it was further appealing. "Obviously, there's a good, ethical feeling you get when you're building something people want," he said. "From a business perspective, the returns on investment are not through the roof as in other business projects, but building a micro-unit deal is something new. To be on the leading edge in Austin for a new kind of development will open a lot of doors down the road."Pages Monday, June 8, 2015 As part of its "Diploma Counts" coverage, EdWeek is offering color coded maps of state graduation rates for various groups. It's a wonderful approach, letting viewers click quickly from group to group and experience the gaps as vivid changes. The darkest blue is used for the strongest results, while the darkest orange-brown identifies the weakest outcomes. Above, results for economically disadvantaged students, with Kentucky's 85% rate shown as well above the national average of 73%, tied with Texas, and better (when you mouse over each jurisdiction) than the results in each of the other states. Below, results for students with limited English proficiency are far lower, though our 64% rate is a bit better than the national 61%. Do give these powerful maps a close look: they'll make sure that the differences sink into your bones. (Added note: Consider a cautious viewing of the map for students with disabilities. It shows a 52% Kentucky graduation rate for students with disabilities, while Kentucky's school report card data file shows a 74% rate. The SRC 2012-13 file matches EdWeek for every other group, so there may be a data glitch somewhere. PrichBlog will try to find out why the numbers don't match and which statistics accurately reflect results for those students.).There have been developed internal combustion engines which are capable of mixing and combusting liquid fuel such as light oil, gasoline, etc., and compressed natural gas (hereinafter also referred to as CNG). For example, in Patent Document 1, there is disclosed an auxiliary fuel ignition type gas engine which uses light oil as auxiliary fuel. In this auxiliary fuel ignition type gas engine, mixed combustion of light oil and natural gas is carried out using the light oil as an ignition source. In addition, in Patent Document 1, there is described a technique in which at the time of light load, only light oil is supplied to the internal combustion engine, and at the time of medium load and high load, light oil and natural gas are supplied to the internal combustion engine. In Patent Document 2, there is disclosed a fuel injection control device which controls fuel injection into cylinders of an internal combustion engine. This fuel injection control device is provided with a reducing agent supply unit that supplies a reducing agent to an exhaust gas purification device. This reducing agent supply unit supplies the reducing agent to the exhaust gas purification device by performing, after main fuel injection, post injection as well as before-post injection small amount injection (pre injection) which is carried out before the post injection and which is smaller in the amount of injection than the post injection, by means of fuel injectors which serve to inject fuel into the cylinders, respectively. In Patent Document 3, there is disclosed that two or more of an oxygen concentration, a CO concentration and an HC concentration, of an exhaust gas are used as control parameters at the time when a reducing agent is supplied into an exhaust gas flowing into an exhaust gas purification device.New spy pictures of an undisguised 2017 Porsche 911 GT3 at the Nürburgring show that the car will get redesigned tail lights and a new rear bumper. The 2017 car will also get a revised front end, with more aggressive air intakes in the front bumper, a redesigned front spoiler, air intakes and new LED indicators, along
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253, 16851, 13765, 5837, 673, 14, 7527, 323, 436, 985, 310, 669, 3549, 5, 443, 6147, 15, 3824, 1783, 273, 436, 985, 4245, 253, 2363, 273, 436 ]	dotted lines showing the $\pm1\sigma$ isochrones. Finally the density of EXOFASTv2 samples is shown in the colour scale of the plotted posterior distribution.[]{data-label="fig:150_hr"}](150_hr){width="\columnwidth"} Figure \[fig:150\_hr\] includes a small collection of points above the main area of convergence. These data are not affected by increasing the run-time of the MCMC analysis or by increasing the burn-in period thus we do not believe them to be an artefact of unfinished fitting. However, since the significance of this region is $\lesssim$10 times lower than the peak we do not find it impactful. ### EXOFASTv2 analysis {#sec:EXOFASTv2 analysis} To perform simultaneous fitting of the SuperWASP detection, the SOPHIE RVs and the follow-up photometry we used the fitting code EXOFASTv2 [@Eastman2017; @Eastman2019]. This tool is designed to fit all the available data and ensure consistency between derived stellar and planetary parameters. EXOFASTv2 explores the given parameter space through a differential evolution Markov chain method using 30000 steps. We use the Gelman-Rubin statistic [@Gelman2003] to check the mixing of the chains as proposed by @Ford2006. We fit a total of 50 free parameters, these are the parameters presented in Table \[tab:MCMC parameters\] as well as limb darkening parameters for each band used and offset baselines and variances to account for any errors in normalisation. For the EXOFASTv2 input parameters we take period and epoch from the initial SuperWASP discovery photometry. Metallicity and effective temperature are taken from the results of spectroscopic analysis. Additionally, we use stellar radius and luminosity as well as parallax and distance from Gaia DR2. Finally we impose a prior on the V-band extinction from @Schlegel1998 and @Schlafly2011 which are used to model the stellar properties through SED fitting. Within EXOFASTv2 we use the MESA Isochrones and Stellar Tracks [MIST, @Dotter2016; @Choi2016] to model the star. This produces an age of $2.18^{+0.58}_{-0.65}$Gyr, which is in reasonable agreement with the [<span style="font-variant:small-caps;">bagemass</span>]{} age in Table \[tab:BAGEMASS properties\]. The best fit values, along with uncertainties, are presented in Table \[tab:MCMC parameters\]. WASP-176b --------- ### Stellar parameters {#sec:Stellar parameters 176} Similar to WASP-150, the stellar parameters of WASP-176 are calculated via a spectral analysis of the CORALIE spectra. The results of this analysis are shown in Table \[tab:Stellar parameters\]. Once again, the second data release of Gaia [@Gaia2016; @Gaia2018] provided some additional stellar parameters presented in Table \[tab:Gaia\]. Gaia was also searched for close companions of WASP-176. To determine the age of WASP-176 we again ran [<span style="font-variant:small-caps;">bagemass</span>]{} and show the results in Table \[tab:BAGEMASS properties\]. The best-fit evolutionary track and isochrone produced from the [<span style="font-variant:small-caps;">bagemass</span>]{} analysis are shown in Figure \[fig:176\_hr\] along with the $1\sigma$ uncertainties. This plot also includes the posterior distribution produced by the MCMC analysis (see section \[sec:MCMC analysis\]). ![[<span style="font-variant:small-caps;">bagemass</span>]{} analysis of WASP-176. The black line shows the Zero Age Main Sequence (ZAMS). The orange line shows the best fit mass track with the dotted lines showing the $\pm1\sigma$ mass tracks. The red line shows the isochrone relating to the best fit age with the dotted lines showing the $\pm1\sigma$ isochrones. Finally the density of MCMC samples is shown in the colour scale of the plotted posterior distribution.[]{data-label="fig:176_hr"}](176_hr){width="\columnwidth"} Once again we see that Figure \[fig:176\_hr\] includes a few points above the main peak. As before we find that these data are not affected by increasing the run-time of the MCMC analysis or by increasing the burn-in period so, again, we do not believe them to be an artefact of unconverged fitting. Since the significance of this region is $\sim$10 times lower than the peak we do not find it impactful. ### EXOFASTv2 analysis {#sec:MCMC analysis} As for WASP-150b we once again use EXOFASTv2 to derive the quoted parameters for WASP-176b. We use the same number of steps, 30000, and utilise the Gelman-Rubin statistic to check the mixing of the chains. We fit 43 free parameters, these are the parameters presented in Table \[tab:MCMC parameters\] as well as limb darkening parameters for each band used and offset baselines and variances to account for any errors in normalisation. In the same way as for WASP-150b we take the EXOFASTv2 input parameters from a combination of the WASP discovery photometry (period and epoch), spectroscopic analysis (metallicity and effective temperature) and Gaia DR2 (stellar radius, luminosity, parallax and distance). Additionally we impose a V-band extinction prior from @Schlegel1998 and @Schlafly2011. We use the MESA Isochrones and Stellar Tracks [MIST, @Dotter2016; @Choi2016] to model the star. This produces an age of $3.69^{+1.9}_{-0.83}$Gyr, which is in good agreement with the [<span style="font-variant:small-caps;">bagemass</span>]{} age in Table \[tab:BAGEMASS properties\]. The best fit values, along with uncertainties, are presented in Table \[tab:MCMC parameters\]. The WASP-176b analysis was first conducted allowing for an eccentric orbit. This resulted in $\chi^2_{ecc} = 11.423$ Repeating the analysis, this time forcing a circular orbit gives $\chi^2_{circ} = 11.358$. Since the discrepancy between these values is negligible it was decided there was insufficient evidence to support eccentricity and thus a circular orbit was assumed. Parameter (unit) WASP-150b WASP-176b ----------------------------------- ----------- ----------- $T_0$ (HJD) $P$ (days) $\Delta F$ $T_{14}$ (days) $b$ $i$ ($^{\circ}$) $e$ $M_\star$ ($\rm M_{\odot}$) $R_\star$ ($\rm R_{\odot}$) $\rho_\star$ ($\rm \rho_{\odot}$) $\log{g_\star}$ (cgs) $T_{eff}$ (K) $[Fe/H]$ $M_{pl}$ ($\rm M_J$) $R_{pl}$ ($\rm R_J$) $\rho_{pl}$ ($\rm \rho_J$) $\log{g_{pl}}$ (cgs) $T_{pl}$ (K) $a$ (AU) : System parameters from MCMC analysis[]{data-label="tab:MCMC parameters"} Discussion and conclusions {#sec:Discussion and conclusions} ========================== WASP-150b --------- WASP-150b is a high density hot Jupiter on a day orbit around its host. With a mass of of $\rm M_J$ and a radius of $\rm R_J$ WASP-150b has a density of $\rm \rho_J$ placing it amongst the highest density planets known. Figure \[fig:density plot\] shows a plot of all the confirmed exoplanets from the NASA exoplanet archive with radius and mass known to an accuracy of $\leq$ 10% and periods of $\leq$ 10 days. Though large, this density is in line with expectations based on the planets mass [@2009AIPC.1094..102C]. ![Scatter plot of all confirmed exoplanets from the NASA exoplanet archive with radius and mass known to an accuracy of $\leq$ 10% and periods of $\leq$ 10 days. The points are then coloured by density in cgs units. WASP-150b is shown as a red diamond and Jupiter is shown as a black diamond for reference (WASP-176b is shown as an orange diamond). The plot also includes lines of constant density to guide the eye.[]{data-label="fig:density plot"}](density){width="\columnwidth"} WASP-150b is also relatively eccentric ($e$ = ). Using equation (3) from @Adams2006 (and assuming $Q_p \sim 10^5$) we see that the approximate circularisation time-scale for this system is $\sim$ Gyr. Our analysis of this system gives the age of this
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1705, 588 ]	July 13. MAGNETISM. /■'roetic/i's Magnetic Lau'. — \\\ an article by Dr. Froelich, in the "Elek. Zeit.," July 5, he calls attention to the law which he recently deduced (see Digest, Aug. 12. 1893, also Feb. 17, and The Electrical World, Feb. 24, p. 23'*), stating that he has since endeavored to verify it by experiments, obtaining good results, but finding that the calculated maximum flux was always smaller than that which had been found experimentally with high magnetizing forces. He concludes that the apparatus with which such measurements are usually made involves a number of errors when liii-h magnetizing forces are used; he refers to those usually used in practice in which the iron is surrounded by a coil, its circuit being com- pleted by an iron yoke; among them are: that the influence of the yoke, as also that of the contact surface, is not eliniinaled with sufficient pre- cision; that the magnetizing coil has an action not only on the sample but also on the yoke, which action was not taken into account with sufficient inecision; that the small test coil is affected not only by the llux through the iion sample; but also by that in the yoke and in the air space, and finally that the sharp ends in the iron give rise to leakage at high magnetization. In order, therefore, to test his formulas, he calculates a seiies of results and curves from the recent researches of Mr. Lehman, published in "Wied. Ann.," vol. 48, page 405, in which the method of KirchholT was used, which is free from the above named errors, and which, it may be safely assumed, gives the true magnetization curve; in tiiis method a complete iron ring surrounded by tie coil was used. Dr. I'loclich gives his formulas, the deduced values of the con.stants and seveial tables of results and curves, showing the dilTerence between the calculated and observed values, the agreement being a very satisfactoiy one ; the above refers to his more complicated but nu)re accurate formu- las, and he therefore concludes that these formulas repiescnt the true magnetizing law of iron; he finds from these results that the maximum llux is very much higher than was usually supposed, and furthermore, tliat it cannot be determined with any accuracy. He also applies his simpler aijproximate formulas to these results and finds that they are veiy reliable for magnetizing forces between H = (> and 11=40 — that is, f<ir the lange used in practice— but that above and below these values they do not apply (it will be remembered that this was a straight line law) ; he concludes, therefore, that his simple formulas can safely be applied in practice, but that the value of the ina.xinuim flux which enters in them is not the true maximum, but is only an apparent one, and therefore has the character of a mathematical constant. UNITS, MEASUREMENTS AND INSTRUMENTS. The Arc as a.S'/anrfarrf.— See abstract under "Rotation of the Electric Arc" .Specific Resistance of Pure Copper. — A Royal Society paper by Messrs. Swan and Rliodin is abstracted in the Lond. "Elec," July 13. Great care was taken to obtain the purest electrolytic copper, only the best of a large niiraber of samples being used and again refined electrolytically : the di- ameters were determined by the specific gravity method ; the absolute spe- cific resistance at 0° C. was calculated from the temperature co-efficients which were carefully determined; the density was 8.9587 at 15° C. ; the specific resistance in C. G. S. unitstpresumably at 0° C, although not so stated) for one sample was 1,603 hard.as drawn, 1,566 for the same sample annealed and 1,559 for another sample annealed; the temperature co-effi- cients were respectively 0.00408. 0.00418, 0.00415; he believes that the mean is the probable correct value, and gives the following as the true values; hard 1,603. soft 1,563; temperature co-efficients 0.00408 and 0.0041(> respectively. (Attention is called by the compiler to the determinations of Mr. Lagarde, given in the Digest, Oct. 7, 1893. further references to the original being given in the Digest, Nov. 18, 1893, and March 17, 1894.) Magnetic Curve Tracer. ^Kccoxi\n% to an editorial in the Lond. "Elec," July 13, Mr. Hess, before the French Academy, proposes to make use of the peculiarities of cathode rays pointed out by Dr. Lenard for obtaining a curve tracer with a pointer without inertia ; cathode rays are made to fall "on a rapidly moving photographic film, the whole "observing space," as Dr. Lenard calls it, being placed within the vari- able electric field to be investigated. Measuring Co-efficients of Induction. — An Academy paper by Mr. Abra- ham, on the measurements and comparison of true co-efficients of induc- tion by alternating currents of high frequency, is abstracted in "L'Ind. Elec," July 10, and more fully in "L'Elec." July 7; a Wheatstoue bridge and telephone are used ; the formulas for the relations are given. Measuring the Efficiency of a Large Motor. — The article by Mr. Rey. mentioned in the Digest last week, is given in abstract in "L'Ind. Elec," July 10 Meter.— The Brocq meter is described and illustrated in "La Lum. Elec," July 7; a solenoid operates a float in a sort of dashpot, the motion of which is registered. TRANSFORMERS. Transformer System. — Mr. Whitcher. in the Lond. "Elec. Rev.," July 13, states that his method (see Digest July 28) is not as described in that journal ; he does not, however, describe it clearly. He states that an extra primary main is used in place of an automatic switch, on the primary side as well as on the secondary, and that he disperses with all automatic mechanism, using only the same number of mains: for large sub-stations he proposes to use a method in which the currents in the two sides of the three-wire system can be varied in phase relatively to each other, from consonance through all values of nppositeness, by means of which the engineer at the central station can control the transformer capacity by the suitable alteration of the phase dilTerence ; he also speaks of controlling it by varying the induction in some of the transformers. Constant Current Transjormer System. — In a description of the Fer- ranti system in "L'Elec," July 7 (see Digest. June -W, under "Ports- mouth"). Mr. Meylan adds a theory of the action of such transformers, showiue that it is questionable whether one can, by this means, obtain a true automatic regulator of the current and concludes that the construc- tion depends on the limits between which regulation is to be effected. Current Ruslies in Tran.'forniers. — Mr. Hay's article is continued in the Lond. "Elec," July 13; he discusses the effect of frequency and finds that the current rushes increase with the periodicity (that is, fie- quency). He then discusses experiments with inductive circuits con taining iron and gives curves and tables; in a certain case the curient rush was 6.74. In the same issue he replies to the comments of Dr. F'leming mentioned in the Digest last week, in which he states th,at the fact that his remarks applied to circuits without iron seems to have been overlooked by that Clitic and hopes th.at his statements will have the effect of shaking the confidence in some of Dr. FMeming's conclusions. AFC AND INCANDE.SCENT LIGHTS. Trojectors.— The "Elek. Zeit.." June 5, contains.an article of some length by Mr. Nerz. He discusses at some length the various statements made in the discussion of the.subject of photometry of projectors, which was published in The Electiical World last year; regarding Prof. S. P. Thompson's statement, he showed that according to that writer one square millimetre of crater has an intensity of 11.1 candles, while the present writer has obtained a maximum value more than ten times as great ; he shows that with the large Schuckeit search light at Chicago, on the assumption that the beam has an angle of 2 degrees, the theoretical point August 4, 1894. THE ELECXRICAIv WORLD. 109 from which the light appears to come will
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string CodeActionMetadataName = "Microsoft.CodeAnalysis.CodeActions.CodeAction"; private static readonly ImmutableArray<string> s_WorkspaceAssemblyNames = ImmutableArray.Create( "Microsoft.CodeAnalysis.Workspaces", "Microsoft.CodeAnalysis.CSharp.Workspaces", "Microsoft.CodeAnalysis.VisualBasic.Workspaces"); public static readonly DiagnosticDescriptor DoNotUseTypesFromAssemblyDirectRule = new DiagnosticDescriptor( DiagnosticIds.DoNotUseTypesFromAssemblyRuleId, s_localizableTitle, s_localizableMessage, DiagnosticCategory.MicrosoftCodeAnalysisCorrectness, DiagnosticSeverity.Warning, isEnabledByDefault: true, description: s_localizableDescription, customTags: WellKnownDiagnosticTags.Telemetry); public static readonly DiagnosticDescriptor DoNotUseTypesFromAssemblyIndirectRule = new DiagnosticDescriptor( DiagnosticIds.DoNotUseTypesFromAssemblyRuleId, s_localizableTitle, s_localizableIndirectMessage, DiagnosticCategory.MicrosoftCodeAnalysisCorrectness, DiagnosticSeverity.Warning, isEnabledByDefault: true, description: s_localizableDescription, customTags: WellKnownDiagnosticTags.Telemetry); protected abstract bool IsNamedTypeDeclarationBlock(SyntaxNode syntax); public override ImmutableArray<DiagnosticDescriptor> SupportedDiagnostics => ImmutableArray.Create(DoNotUseTypesFromAssemblyDirectRule, DoNotUseTypesFromAssemblyIndirectRule); public override void Initialize(AnalysisContext context) { context.EnableConcurrentExecution(); context.ConfigureGeneratedCodeAnalysis(GeneratedCodeAnalysisFlags.Analyze); context.RegisterCompilationStartAction(compilationStartContext => { if (compilationStartContext.Compilation.GetOrCreateTypeByMetadataName(CodeActionMetadataName) == null) { // No reference to core Workspaces assembly. return; } INamedTypeSymbol? diagnosticAnalyzer = compilationStartContext.Compilation.GetOrCreateTypeByMetadataName(WellKnownTypeNames.MicrosoftCodeAnalysisDiagnosticsDiagnosticAnalyzer); if (diagnosticAnalyzer == null) { // Does not contain any diagnostic analyzers. return; } var hasAccessToTypeFromWorkspaceAssemblies = false; var namedTypesToAccessedTypesMap = new ConcurrentDictionary<INamedTypeSymbol, ImmutableHashSet<INamedTypeSymbol>>(); var diagnosticAnalyzerTypes = new ConcurrentBag<INamedTypeSymbol>(); compilationStartContext.RegisterSymbolAction(symbolContext => { var namedType = (INamedTypeSymbol)symbolContext.Symbol; if (namedType.DerivesFrom(diagnosticAnalyzer, baseTypesOnly: true)) { diagnosticAnalyzerTypes.Add(namedType); } var usedTypes = GetUsedNamedTypes(namedType, symbolContext.Compilation, symbolContext.CancellationToken, ref hasAccessToTypeFromWorkspaceAssemblies); var added = namedTypesToAccessedTypesMap.TryAdd(namedType, usedTypes); Debug.Assert(added); }, SymbolKind.NamedType); compilationStartContext.RegisterCompilationEndAction(compilationEndContext => { if (diagnosticAnalyzerTypes.IsEmpty \|\|!hasAccessToTypeFromWorkspaceAssemblies) { return; } var typesToProcess = new Queue<INamedTypeSymbol>(); var processedTypes = new HashSet<INamedTypeSymbol>(); var violatingTypeNamesBuilder = new SortedSet<string>(); var violatingUsedTypeNamesBuilder = new SortedSet<string>(); foreach (INamedTypeSymbol declaredType in namedTypesToAccessedTypesMap.Keys) { if (!diagnosticAnalyzerTypes.Contains(declaredType)) { continue; } typesToProcess.Clear(); processedTypes.Clear(); violatingTypeNamesBuilder.Clear(); violatingUsedTypeNamesBuilder.Clear(); typesToProcess.Enqueue(declaredType); do { var typeToProcess = typesToProcess.Dequeue(); Debug.Assert(typeToProcess.ContainingAssembly.Equals(declaredType.ContainingAssembly)); Debug.Assert(namedTypesToAccessedTypesMap.ContainsKey(typeToProcess)); foreach (INamedTypeSymbol usedType in namedTypesToAccessedTypesMap[typeToProcess]) { if (usedType.ContainingAssembly!= null && s_WorkspaceAssemblyNames.Contains(usedType.ContainingAssembly.Name)) { violatingTypeNamesBuilder.Add(usedType.ToDisplayString()); violatingUsedTypeNamesBuilder.Add(typeToProcess.ToDisplayString()); } if (!processedTypes.Contains(usedType) && namedTypesToAccessedTypesMap.ContainsKey(usedType)) { typesToProcess.Enqueue(usedType); } } processedTypes.Add(typeToProcess); } while (typesToProcess.Count!= 0); if (violatingTypeNamesBuilder.Count > 0) { string[] args; DiagnosticDescriptor rule; if (violatingUsedTypeNamesBuilder.Count == 1 && violatingUsedTypeNamesBuilder.Single() == declaredType.ToDisplayString()) { // Change diagnostic analyzer type '{0}' to remove all direct accesses to type(s) '{1}' rule = DoNotUseTypesFromAssemblyDirectRule; args = new[] { declaredType.ToDisplayString(SymbolDisplayFormat.MinimallyQualifiedFormat), string.Join(", ", violatingTypeNamesBuilder) }; } else { // Change diagnostic analyzer type '{0}' to remove all direct and/or indirect accesses to type(s) '{1}', which access type(s) '{2}' rule = DoNotUseTypesFromAssemblyIndirectRule; args = new[] { declaredType.ToDisplayString(SymbolDisplayFormat.MinimallyQualifiedFormat), string.Join(", ", violatingUsedTypeNamesBuilder), string.Join(", ", violatingTypeNamesBuilder) }; } Diagnostic diagnostic = declaredType.CreateDiagnostic(rule, args); compilationEndContext.ReportDiagnostic(diagnostic); } } }); }); } private ImmutableHashSet<INamedTypeSymbol> GetUsedNamedTypes(INamedTypeSymbol namedType, Compilation compilation, CancellationToken cancellationToken, ref bool hasAccessToTypeFromWorkspaceAssemblies) { var builder = PooledHashSet<INamedTypeSymbol>.GetInstance(); foreach (var decl in namedType.DeclaringSyntaxReferences) { var syntax = decl.GetSyntax(cancellationToken); // GetSyntax for VB returns the StatementSyntax instead of BlockSyntax node. syntax = syntax.FirstAncestorOrSelf<SyntaxNode>(node => IsNamedTypeDeclarationBlock(node), ascendOutOfTrivia: false)?? syntax; #pragma warning disable RS1030 // Do not invoke Compilation.GetSemanticModel() method within a diagnostic analyzer var semanticModel = compilation.GetSemanticModel(syntax.SyntaxTree); #pragma warning restore RS1030 // Do not invoke Compilation.GetSemanticModel() method within a diagnostic analyzer var nodesToProcess = new Queue<(SyntaxNode node, bool inExecutableCode)>(); nodesToProcess.Enqueue((node: syntax, inExecutableCode: false)); do { (SyntaxNode node, bool inExecutableCode) nodeToProcess = nodesToProcess.Dequeue(); var node = nodeToProcess.node; var inExecutableCode = nodeToProcess.inExecutableCode; if (!inExecutableCode &&!ReferenceEquals(node, syntax) && IsNamedTypeDeclarationBlock(node)) { // Skip type member declarations. continue; } if (node is TTypeSyntax typeSyntax) { var typeInfo = semanticModel.GetTypeInfo(typeSyntax, cancellationToken); AddUsedNamedTypeCore(typeInfo.Type, builder, ref hasAccessToTypeFromWorkspaceAssemblies); } if (!inExecutableCode) { var operationBlock = semanticModel.GetOperation(node, cancellationToken); if (operationBlock!= null)
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"Back to the graveyard, please." "That's all, your honor. Ms. Caine told me I needed to be a witness." The judge looked at me. "A witness of what, Ms. Caine?" Stupid judge. He'd taken the legs out of the testimony. I'd have to prop it back up. "If I may continue to question my own witness?" I said. "Don't take that tone with the court," the judge said. Manyon sat back with a half smile on his face. I said to Leon, "You saw a figure before I took you down, isn't that true?" "Yes. Sandy." "Only it couldn't have been, because he was too young?" "Well, yes." "Did this figure change shape as far as you know?" "Objection, your honor," said Manyon. "Assumes a fact not in evidence. The witness just said he thought it was Sandy Koufax. That's all. We have no evidence of something changing shape, whatever that is supposed to mean." "Agreed," said the judge. "You will have to rephrase your question, Ms. Caine." "What did you see after you got up from the ground?" I asked. "Well now, I thought I saw something fuzzy with long nails. Not that I was shocked. My ex-wife looked the same way—" "Your honor, if you please," Manyon said. "Just answer the questions without your color commentary," the judge said. "I'm tryin' to, Judge, it's just the way I have of speakin'." Judge Blankenship rubbed his eyes. "What about the nails?" I asked. "Long. Really long. I wouldn't want to be scratched by those things... Sorry, judge, that's the way I feel." "Go on," Blankenship said to me. "Anything else?" I asked. "The eyes," Jones said. "She had terrible eyes." "Object to the word she," Manyon said. "Sustained." "What do you mean by terrible?" I said. "Mean. Deadly. Like Bob Gibson." "Who?" "A pitcher you never would want to face, I can tell you. He'd—" "Mr. Jones," the judge said, "that will do." "May we approach the bench, your honor?" Manyon said. Up to the bench we went. Manyon said, "Your honor, the testimony of this witness is irrelevant and immaterial. There has been no proof offered that whatever this man thinks he saw on some given night is the boy's mother. This testimony has nothing to do with custody and everything to do with Ms. Caine trying desperately to cloud the issues." "I have to agree," the judge said. "Unless you can provide a connection to the boy's mother, Mr. Jones's testimony is not germane to these proceedings. Can you provide such proof?" Fake it till you make it. "Yes, your honor. If I can call an expert witness." "Is he here?" "In a way." "What's that mean?" "You can't see him yet. He'll manifest himself." "Ms. Caine, if you—" "Let me bring him in." "Then do it. Mr. Jones will step down, subject to recall. But until you provide a foundation for his testimony, I will not consider it in the slightest." CHAPTER 34 "Cool Train" Jones looked disappointed as he left the stand. I'm sure he had more baseball stories to tell. Then I said, "I call Darren McGavin." Eyes turned toward the courtroom gallery. Darren McGavin, dressed as I had first seen him, came forward. Until that point he had been invisible. He'd told me he preferred it that way. No need to cause a fuss, he'd said. Some people still remembered Kolchak. However, it did look like he popped out of nowhere. "What... just happened there?" the judge said. "Mr. McGavin is ready to be sworn," I said. "I mean, I mean. I don't know what I mean. I thought I saw. Never mind. Swear the witness." "One moment," Charles Beaumont Manyon said. "I believe I can help your honor with the confusion." "That'll be the day," I said. Without any warning, Manyon picked up a copy of the evidence code from his counsel table, walked over to Darren McGavin, and tossed it at him. The book passed completely through the ghost and thudded to the floor. The people in the gallery gasped. One woman screamed. The poor bailiff looked like he didn't know what to do. "This is a specter," Manyon said. "A ghost. A dead person. Dead people cannot testify in court." "And where does it say that?" I asked. "There is no provision against dead people testifying. The test is competence, and Mr. McGavin is certainly competent to testify. I would remind Mr. Manyon that a witness is presumed competent under the evidence code itself "—I dramatically picked up the tome from the floor and held it aloft—"unless there has been some showing of an inability on the part of the witness to perceive, remember, communicate, or appreciate the oath. Mr. McGavin, despite being a ghost, meets all the tests." Blankenship's lips were moving. Little spitballs were forming at the corners of his mouth. His eyes shifted back and forth as if on involuntary status. "Somebody get the judge a glass of water," I said. His clerk, a lovely but confused young woman, attended to the water. Manyon glowered at me. I don't take to the glower. We all waited for the judge to gather himself. When he finally looked up, he said, "I'm not going to make my decision yet. I will hear the testimony and then decide." "But your honor," Manyon said. "Who is the judge around here? Swear him in and let's get on with it!" "Mr. McGavin, you were an actor, is that correct?" "Yes, I was. Loved it. It was fun." "You performed on stage, screen, and television?" "That's right." "You appeared on a series called Kolchak: the Night Stalker, is that right?" The court reporter asked me to spell it, so I did. "That's right," Darren McGavin's ghost said. "It appeared on the ABC network, for one season in the 1970s. Should have run longer." "But the series has caught on with new fans, is that right?" "Wonderful things, the DVDs, the Netflix deal. Wish we'd had 'em back when I was doing the show." "What was the premise of this series, Mr. McGavin?" "Well, Carl Kolchak, he was a newspaper crime reporter, you see, and he would investigate these stories and find out there was something strange going on each time. A different sort of supernatural explanation for things. You know, vampires, werewolves, and the like. We got into some of the more obscure monsters, like the Indian bear spirit. And so on." "And the Rakshasa?" "Yes, that was one of our more popular episodes. The Hindu demon." "Now, Mr. McGavin, during the course of these episodes did you do any of your own research into the substance of the show?" "Yes, I did. I took a great interest in each of them." "Will you please tell the court what you discovered about the Rakshasa." "Certainly." He turned toward the judge, whose ashen face was frozen in a state of imperial unbelief. "Well, your honor, it seems these Rakshasas are very ugly in their native form, with long nails and flesh-eating tendencies. They are the souls of extremely wicked people. Being a Rakshasa requires something more than just normal, everyday evil. You have to be like a Genghis Khan or a Nero." "Now," I said, "what can a Rakshasa do to confuse us?" "They can appear to you to be someone you absolutely trust. They can go into your mind and take out a picture of that person and become that person in your eyes. They use this ploy to get you to approach them, you see, until they can reach out and kill you." "So, hypothetically speaking, if someone had been a professional baseball player, would the Rakshasa be able to appear to him as a former teammate?" "Quite easily." Manyon stood up. "Your honor, we've had quite enough of this. There is no relevance here, no foundation for these questions. If Ms.
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And we conclude by the uniqueness of the martingale problem associated to $D$. $\square$ Let us note eventually that when $2k$ equals the multiplicity associated with a Riemannian symmetric space of noncompact type $G/K$, then the radial HO-process coincide with the radial part of the Brownian motion on this symmetric space (see [@HO], or [@Schap]). For instance if $G=SL_n$, then $k=\frac{1}{2}$ in the real case, $k=1$ in the complex case, and $k=2$ in the quaternionic case. So most of our results about radial processes generalize known results of the probabilistic theory on symmetric spaces. The Dunkl processes {#definitiondunkl} ------------------- We recall now the definition of the Dunkl process and of its radial part. Let ${\mathcal{R}}'$ be a reduced root system (i.e. such that $\forall \alpha \in {\mathcal{R}}'$, $2\alpha \notin {\mathcal{R}}'$), but non necessarily integral (i.e. we do not assume condition $3$ in the definition), and let $k'$ be a multiplicity function on ${\mathcal{R}}'$. The Dunkl Laplacian ${\mathcal{L}}'$ is defined for $f\in C^2({\mathfrak{a}})$, and $x\in {\mathfrak{a}}_{\text{reg}}$ by $$\begin{aligned} {\mathcal{L}}' f(x)&=& \frac{1}{2}\Delta f(x)+ \sum_{\alpha \in {\mathcal{R}}'^+}k'_\alpha \frac{1}{(\alpha,x)}\partial_\alpha f(x) \\ &+& \sum_{\alpha \in {\mathcal{R}}'^+}k'_\alpha \frac{1}{(\alpha,x)^2}\{f(r_\alpha x)-f(x)\}.\end{aligned}$$ It was proved by Rösler in [@Ros] that ${\mathcal{L}}'$ defined on ${\mathcal{S}}({\mathfrak{a}})$, the classical Schwartz space on ${\mathfrak{a}}$, is a closable operator, which generates a Feller semigroup on $C_0({\mathfrak{a}})$. Naturally the Dunkl process is the Feller process defined by this semigroup. Now our proof (in [@Schap]) that the operator $D$ defined on ${\mathcal{C}}({\mathfrak{a}})^W$ is closable, also holds in the Dunkl setting. Thus we may define the radial Dunkl process as the Feller process on $\overline{{\mathfrak{a}}_+}$ with generator the closure of $(L',{\mathcal{S}}({\mathfrak{a}})^W)$, where $L'$ is the differential part of ${\mathcal{L}}'$, and ${\mathcal{S}}({\mathfrak{a}})^W$ is the subspace of ${\mathcal{S}}({\mathfrak{a}})$ of $W$-invariant function (identified with their restriction to $\overline{{\mathfrak{a}}_+}$). In this way we get a new characterization of the radial Dunkl process as solution of a martingale problem. Naturally Proposition \[premiereprop\] holds as well in the Dunkl setting, thus our definition of the radial Dunkl process agrees with the usual one. Eventually the intrinsic Brownian motion is by definition the radial Dunkl process of parameter $k'=1$. The radial HO-process as a Dirichlet process ============================================ The goal of this section is to obtain an explicit semimartingale decomposition of the radial HO-process. In the case of root systems of type $A$, it was obtained by Cépa and Lépingle (see [@Cep] and [@CepLep2] Theorem $2.2$). We present here another approach, which is based on the theory of Dirichlet processes. Our reference for this theory will be [@FukOT]. We consider $(D,{\mathcal{C}}({\mathfrak{a}})^W)$ as a symmetric operator on $L^2(\overline{{\mathfrak{a}}_+},\mu)$ (simply denoted by $L^2$ in the sequel). We have seen in [@Schap] that this operator is closable. We denote by $(D,{\mathcal{D}}_2(D))$ its closure. Its associated semigroup is just the extension of $(P_t^W,t\ge 0)$ on $L^2$. It is defined for $f,g\in L^2$ and $t\ge 0$ by $$P_t^Wf(x)= \int_{\overline{{\mathfrak{a}}_+}}p_t^W(x,y)f(y)d\mu(y).$$ We denote by ${\mathcal{E}}$ the associated Dirichlet form, and by ${\mathcal{F}}$ its domain (${\mathcal{D}}_2(D)\subset {\mathcal{F}}$). It is determined for $f,g \in {\mathcal{D}}_2(D)$ by $${\mathcal{E}}(f,g):=-\int_{\overline{{\mathfrak{a}}_+}}f(x)Dg(x)d\mu(x)=-\int_{\overline{{\mathfrak{a}}_+}}Df(x)g(x)d\mu(x).$$ The fact that ${\mathcal{E}}$ is a regular Dirichlet form with special standard core the algebra ${\mathcal{C}}({\mathfrak{a}})^W$, results from the density of this space in $C_0(\overline{{\mathfrak{a}}_+})$ (see Lemma $5.1$ in [@Schap]) and Theorem $3.1.2$ in [@FukOT]. We have seen in [@Schap] that when $f\in L^1({\mathfrak{a}},\mu)$, then $Gf:x \mapsto \int_0^\infty P_t^Wf(x)dt$ is a.e. finite. In the terminology of [@FukOT], this means that the Dirichlet form ${\mathcal{E}}$ (or the semigroup $P_t^W$) is transient. This implies in particular that the process tends to infinity when $t\to \infty$. In the sequel we will prove a law of large numbers which makes this fact precise. It implies also that we may consider ${\mathcal{F}}$, equipped with its inner product ${\mathcal{E}}$, as a Hilbert space (see [@FukOT] chapter $2$). For $i=1,\dots,n$, we denote by $\varphi_i :x\mapsto x_i$ the coordinate functions on $\overline{{\mathfrak{a}}_+}$. For $A>0$, let $\varphi_i^A \in C^\infty(\overline{{\mathfrak{a}}_+})$ be a function which coincides with $\varphi_i$ on $\{\|x\|\le A\}$, and which is null on $\{\|x\|\ge A+1\}$. For all $A >0$, $\varphi_i^A \in {\mathcal{F}}$, and for all $v\in {\mathcal{C}}({\mathfrak{a}})^W$, $${\mathcal{E}}(\varphi_i^A,v)=-\int_{\overline{{\mathfrak{a}}_+}}D\varphi_i^A vd\mu.$$ Proof of the lemma: Let $(u_n)_n\in {\mathcal{C}}({\mathfrak{a}})^W$ which converges uniformly to $\varphi_i^A$ as in Lemma $5.1$ in [@Schap]. We will assume that $\|u_n-\varphi_i^A\|_\infty \le \frac{1}{n}$ for all $n$. We have to prove that it is an ${\mathcal{E}}$-Cauchy sequence. Let $n<m$ be two integers. We have $$\begin{aligned} {\mathcal{E}}(u_n-u_m,u_n-u_m) &=& \int_{d(x,\partial {\mathfrak{a}}_+)\le \frac{1}{m}}D(u_n-u_m)(u_n-u_m)d\mu \\ &+& \int_{\frac{1}{m}\le d(x,\partial {\mathfrak{a}}_+)\le \frac{1}{n}} D(u_n-u_m)(u_n-u_m)d\mu \\ &+& \int_{d(x,\partial {\mathfrak{a}}_+)\ge \frac{1}{n}}D(u_n-u_m)(u_n-u_m)d\mu.\end{aligned}$$ By Lemma $5.1$ in [@Schap], the integrand in the first integral is bounded, up to a constant, by $\frac{m}{n}$. But $\mu(\{d(x,\partial {\mathfrak{a}}_+)\le \frac{1}{m}, \|x\|\le A+1\})$ is bounded, up to a constant, by $\frac{1}{m}$. Thus the first integral tends to $0$ when $n\to \infty$. The same argument applies for the second integral. The third integral is naturally bounded, up to a constant, by $\frac{1}{n}$. Now always by Lemma $5.1$ in [@Schap], the sequence $(D u_n)_n$ is dominated, up to a constant, by $x\mapsto \frac{1}{d(x,\partial {\mathfrak{a}}_+)}+\sum_\alpha \coth \frac{\alpha}{2}$ on $\|x\|\le A
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326, 310, 15, 1244, 326, 457, 84, 253, 4154, 323, 15199, 15, 16508, 290, 253, 10630, 285, 2136, 13, 627, 457, 84, 760, 581, 7967, 2101, 3109, 1669, 13, 9059, 253, 6018, 1362, 16561, 10823, 27, 2208, 13, 253, 653, 3109, 273, 1390, 17942, 15, 733, 476, 1918, 952, 2583, 407 ]	n3311106.md.png'/></a> <br/> 原文地址（需翻墙访问）：http://www.soundofhope.org/gb/2019/11/04/n3311106.html ------------------------ #### [首页](https://github.com/gfw-breaker/banned-news/blob/master/README.md)  \|  [一键翻墙软件](https://github.com/gfw-breaker/nogfw/blob/master/README.md)  \| [《九评共产党》](https://github.com/gfw-breaker/9ping.md/blob/master/README.md#九评之一评共产党是什么) \| [《解体党文化》](https://github.com/gfw-breaker/jtdwh.md/blob/master/README.md) \| [《共产主义的终极目的》](https://github.com/gfw-breaker/gczydzjmd.md/blob/master/README.md) <img src='http://gfw-breaker.win/banned-news/pages/soh_zgxw/n3311106.md' width='0px' height='0px'/>Inverkeithing railway station Inverkeithing railway station serves the town of Inverkeithing in Fife, Scotland. The station is managed by Abellio ScotRail and is on the Fife Circle Line, north west of. The station is popular with commuters travelling to Edinburgh from Fife and beyond, thanks to its location beside the M90 motorway. Immediately north of the station, the Fife Circle Line splits in two - the main line continuing along the coast via whilst the branch heads inland towards Dunfermline. History It opened in 1877, at the same time as the tracks of the Dunfermline and Queensferry Railway. Facilities Two large free of charge park and ride car parks are provided. The station is currently staffed for all trains and has public toilets, and a ticket hall. There is also a waiting room and a wheelchair accessible footbridge. Services Journey times as low as 15 minutes are available to as CrossCountry, London North Eastern Railway and Abellio ScotRail express services between Edinburgh and stop here. Some services between Edinburgh and also stop at Inverkeithing. Mondays to Saturdays daytimes, four Fife Circle Line trains per hour go southbound to Edinburgh. Northbound, services run every half-hour to, and half-hourly to. One of the former & both of the latter continue to. Evenings and Sundays, two trains per hour go southbound to Edinburgh and two per hour go along the Fife Circle one in each direction (one via Dunfermline and one via Kirkcaldy). Monday to Saturday - most daytime ScotRail services to Aberdeen and Inverness no longer stop here (though a few calls are made to both destinations in the early morning & evening). The primary longer distance service is provided by half-hourly semi-fast trains from Edinburgh to either Perth or Dundee (hourly to each), which serve most stations north of Kirkcaldy. There is a once daily train to via Winchburgh Junction and each morning, returning in the evening peak. On Sundays, there is a limited service to Perth & Inverness and a mostly hourly service to Dundee & Aberdeen. London North Eastern Railway services between Aberdeen, London King's Cross and Leeds call at Inverkeithing, as do CrossCountry services between Aberdeen or Dundee and Plymouth/Penzance. References External links Bus service to Edinburgh Airport Video footage of Inverkeithing railway station Category:Railway stations in Fife Category:Former North British Railway stations Category:Railway stations opened in 1877 Category:Railway stations served by Abellio ScotRail Category:Railway stations served by Caledonian Sleeper Category:Railway stations served by CrossCountry Category:Railway stations served by London North Eastern Railway Category:1877 establishments in ScotlandQ: How to redefine the names for the standard keywords in C# I have the interesting idea. I want to redefine the keywords in C#, like replace the if keyword to the MyIf or something else. Do someone have any idea about how to do it? As I think it have to look something like this: namespace { #define MyIf = if; #define MyElse = else; ... public someclass { public void someMethod() { MyIf(true) { ... } MyElse { ... } } } } Added: Maybe there is the way how to make the C++ or C library which will redefine the part of standard core of C#? Notice. I know that it is the bad programming practice and I ask all the programmers to not use the answer in your enterprise code. A: That's not possible -- C# does not have a preprocessor like C and C++ do, so there is no mechanism to transform the source before the compiler sees it. And of course the compiler will only recognize the standard if, so there is also no other option that somehow transforming the source before the compiler sees it. Even if it were possible, it would be just a step below Cthulhu in the horror scale. A: In c# you can override the overloadable operators (+, -, ==) more info here: http://msdn.microsoft.com/en-us/library/8edha89s(v=vs.80).aspx But you can't really override conditional operators. The same goes for these operators =,.,?:, ->, new, is, sizeof, typeof, they cannot be overloaded. C# does not support macros, but of course you could write a custom parser that handles macros before eventually sending your code to the c# compiler, take a look at Microsoft Roslyn for that. http://msdn.microsoft.com/en-us/vstudio/roslyn.aspx Is It Better to Save or to Spend? Restricted as this page usually is to questions (and answers), its posts can, I realize, seem more than a bit off the news. This is especially true when the economic world is roiling, as it so often has been of late. So let today’s post be a meditation on the roil and in particular, the center-stage question facing the U.S. and Europe, one that has prompted occasionally heated exchanges on my Twitter. The quandary is obvious: stimulus or austerity? In economic jargon, Keynesian or the Austrian School? In plainer terms, save or spend? But which is the right answer? Each side is championed these days, as it was in the last Great Downturn, by Democrats on the one hand, and Republicans on the other — and abroad, by their political equivalents. This cartoon from the conservative Chicago Tribune in 1934 illustrates the Republican point of view in reaction to the spending of the New Deal. Obama a “socialist”? Note that the Roosevelt administration (in the runaway wagon) is supposedly “communist”, following the script of the man at the lower left. That’s Leon Trotsky, once a leader of the Soviet Union and its Red Army. By 1934, he had long since been exiled by Stalin and was living in France, but the symbolic value of his image apparently remained vivid enough for the average American. (Or maybe the Trib hadn’t kept up with times.) Caricature assassination aside, the essence of New Deal Keynesian spending is simple and seemingly sensible: that there’s nothing worse than idle resources and the very worst resource to idle are human beings, for reasons both political and economic. The political cost of idle hands is screamingly obvious: an unemployed, disaffected, meaner citizenry. (See Benjamin Friedman’s major book of 2005, “The Moral Consequences of Economic Growth,” for the damages of contraction. Or glance at Germany after the Great Depression of the early ’30s.) When citizens lose their jobs, they can’t afford to keep spending. When consumer spending stalls, businesses see no reason to make new investments — “Who will buy?”, the song from “Oliver!”, springs to the mind’s ear. Businesses slow their spending, too. The quick fix for this problem — for decades — has been lowering short-term interest rates to make borrowing cheaper and thus kick start spending. But it doesn’t work if interest rates are at zero, as they are now. You can’t have a negative interest rate. Unless you give people money, that is. And that’s the argument for stimulus. Absent the consumer and business, there’s only one Big Spender left, argue the Keynesian Democrats: government, the spender of last resort. It can give people money by
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(3) The cells were incubated with 2 μL of TdT-enzyme and 48 μL of Biotin-dUTP per specimen for 60 min at 37°C. The cells were terminated for 10 min, and were consequently incubated with streptavidin-HRP (50 μL per specimen) conjugate diluted at 1:50 in sample diluent for 30 min. (4) The cells were washed three times with PBS, and were consequently incubated with diaminobenzidine solution (200 μL per specimen) for 10 min. At last, the cells were rewashed twice with PBS, and were consequently imaged under an XDS-1B inverted biological microscope \[[@B30]\]. Flow cytometry analysis ----------------------- Prepared MGC-803 cells (1×10^6^/mL) were washed twice with cold PBS and then re-suspended gently in 500 μL binding buffer. Thereafter, cells were stained in 5 μL Annexin V-FITC and shaked well. Finally, 5 μL PI was added to these cells and incubated for 20 min in a dark place, analyzed by FACS Calibur, Becton Dickinson \[[@B31],[@B32]\]. Caspase 3 enzyme assay ---------------------- Cells were collected after treatment with BTA and OEA at 2.5, 5, and 10 μM for 12 h, respectively. Prepared MGC-803 cells (1×10^6^/mL, 5 ml) were washed twice with cold PBS. Then, 100 μL of lysis buffer was added to the cells for 25 min on ice and centrifuged at 16000 g for 15 min. 80 μL of reaction buffer and 10 μL of Ac-DEVED-pNA were added to 10 μL of supernatant liquid. After incubating at 37°C for 2--3 h in darkness, the absorbance was measured at 405 nm, with the lysis buffer and reaction buffer as control Caspase 9 enzyme assay ---------------------- Cells were collected after treatment with BTA and OEA at 2.5, 5, and 10 μM for 12 h, respectively. Prepared MGC-803 cells (1×10^6^/mL, 5 ml) were washed twice with cold PBS. Then, 100 μL of lysis buffer was added to the cells for 25 min on ice and centrifuged at 16000 g for 15 min. 80 μL of reaction buffer and 10 μL of Ac-LEHD-pNA were added to 10 μL of supernatant liquid. After incubating at 37°C for 2--3 h in darkness, the absorbance was measured at 405 nm, with the lysis buffer and reaction buffer as control. Western botting analysis ------------------------ Cells were collected after treatment with BTA and OEA at 2.5, 5, and 10 μM for 12 h, respectively. Western blotting analysis was performed as previously described \[[@B33]\], using the following antibodies at dilutions of 1:500 to 1:1000: anti-p53, anti-Bax, and anti-β actin (Cell signaling technology, Beverly, MA). Statistical analysis -------------------- All statistical analyses were performed using SPSS 10.0, and the data were analyzed using one-way ANOVA. The mean separations were performed using the least significant difference method. Each experiment was performed in triplicate, and all experiments were run thrice and yielded similar results. Measurements from all the replicates were combined, and the treatment effects were analyzed. Results and discussion ====================== The roots of Toona sinensis collected from Guizhou province were studied, and fifteen compounds were isolated from the plants. The extraction and purification process of the compounds from the plant and their NMR data are presented in Additional file [1](#S1){ref-type="supplementary-material"}. The potential effect of the compounds from Toona sinensis was investigated on the viability of MGC-803, PC3, A549, MCF-7, and NIH3T3 cells by MTT assay, with ADM (Adriamycin) being used as the positive control and culture medium containing 0.1% DMSO used as the negative control. The inhibitory percentage of cancer cells was treated with 20 μmol/L of each compound for 72 h. The results are summarized in Table [1](#T1){ref-type="table"}. It could be seen from Table [1](#T1){ref-type="table"} that both of BTA and OEA showed potent antitumor activities against MGC-803 and PC3 cell lines. The inhibitory ratios of BTA and OEA at 72 h after treatment were 56.1% and 45.2% against MGC-803 cells, 63.4% and 42.5% against PC3 cells, 22.1% and 23.6% against NIH3T3 normal cell line, respectively. In addition, BTA also had good activities against MCF-7 cells, with inhibitory ratio of 51.2%. Thus, the two compounds were less toxic on normal cells than on the investigated cancer cell lines. ###### Antitumor activities of the isolated compounds on the proliferation of different cell lines Compound Inhibitory Rate for Different Cell Lines (%, mean ± SD)^a^ ------------------------------------ -------------------------------------------------------------------- ------------ ------------ ------------ ------------ β-sitosterol (1) 23.5 ± 2.1 16.5 ± 2.3 12.6 ± 3.1 18.9 ± 1.7 5.6 ± 2.4 α-Amyrin (2) 23.5 ± 5.4 17.8 ± 4.9 7.8 ± 1.5 10.4 ± 1.8 7.6 ± 4.5 Daucosterol (3) 12.3 ± 4.1 9.8 ± 3.6 4.5 ± 1.8 7.2 ± 5.2 4.3 ± 2.3 Quercetin (4) 17.2 ± 1.7 22.7 ± 1.4 16.9 ± 2.4 42.2 ± 1.6 4.2 ± 2.5 (+)-Catechin (5) 52.1 ± 5.7 49.6 ± 2.3 45.3 ± 3.2 37.6 ± 3.9 28.9 ± 4.3 (−)-Epicatchin (6) 45.5 ± 4.1 50.6 ± 1.6 47.1 ± 1.1 43.2 ± 3.6 22.5± 3.8 Kampferol (7) 58.2 ± 3.0 46.1 ± 5.9 42.0 ± 2.2 39.2 ± 6.8 11.1 ± 6.7 3-Oxours-12-en-28-oic acid (8) 45.2 ± 2.0 42.5 ± 1.4 35.9 ± 0.8 37.2 ± 1.5 23.6 ± 1.3 Ursolic acid (9) 52.1 ± 2.2 55.6 ± 2.4 37.6 ± 1.7 47.8 ± 1.2 21.7 ± 4.9 Betulonic acid (10) 56.1 ± 2.6 63.4 ± 4.2 35.2 ± 2.4 51.2 ± 4.4 22.1 ± 6.2 Gallic acid (11) 55.7± 1. 9 40.2 ± 4.2 46.3 ± 3.6 33.1 ± 1.4 13.6 ± 2.2 Betulinic acid (13) 36.9 ± 1.6 23.6 ± 3.4 33.5 ± 2.3 41.6 ± 3.7 23.4 ± 2.9 ADM 92.1 ± 1.3 93.4 ± 2.6 96.2 ± 0.8 91.1 ± 2.2 99.4 ± 0.4 Note: ^a^ Inhibitory percentage of cells treated with each compound 20 μmol/L for 72 h and SD = standard deviation. To best of our knowledge, the two compounds, BTA and OEA, were obtained from Toona sinensis for the first time. It was also found to have the greatest potency against the growth of human cancer cell lines and little toxic effect on NIH3T3 cells among the isolated constituents. Further experiments found that proliferation of these four cancer cells were significantly inhibited by BTA and OEA in a concentration-dependent manner, as shown in Figure [1](#F1){ref-type="fig"}A and [1](#F1){
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253, 1083, 15, 8167, 10017, 326, 253 ]	mistrial. I will deny the motion." Defense counsel said nothing further on the issue. The next day the trial court expressed concern that it should have given a limiting instruction regarding Gutierrez's references to Susanville and stated that it would, if requested, strike that portion of the witness's testimony. The court invited defense counsel to propose a limiting instruction. Although defense counsel initially advised he would do so, defense counsel later declined for fear of highlighting the challenged testimony. He explained that, for the same reason, he had not requested a limiting instruction the previous day when he made his motion. (1) Defendant claims the mistrial should have been granted because the prosecutor committed misconduct by improperly eliciting Gutierrez's testimony. Defendant has forfeited this claim. "`[A] defendant may not complain on appeal of prosecutorial misconduct unless in a timely fashionand on the same groundthe defendant made an assignment of misconduct and requested that the jury be admonished to disregard the impropriety. [Citation.]'" (People v. Stanley (2006) 39 Cal.4th 913, 952 [47 Cal.Rptr.3d 420, 140 P.3d 736].) When defendant eventually moved for a mistrial at the conclusion of Gutierrez's testimony, he did so only on the basis of "the response of the witness." He did not argue that the prosecutor had improperly elicited the challenged responses. Additionally, defendant rejected the trial court's offer to admonish the jury. In any event, there was no misconduct. The defense chose to pursue the subject of the collect telephone calls and their cost. The prosecutor's redirect was permissible. Gutierrez nonresponsively volunteered that defendant's calls were made "before he got out in December." (2) The court did not abuse its discretion in denying the motion for a mistrial. "A mistrial should be granted if the court is apprised of prejudice that it judges incurable by admonition or instruction. [Citation.] Whether a particular incident is incurably prejudicial is by its nature a speculative matter, and the trial court is vested with considerable discretion in ruling on mistrial motions. [Citation.]" (People v. Haskett (1982) 30 Cal.3d 841, 854 [180 Cal.Rptr. 640, 640 P.2d 776].) A motion for a mistrial should be granted when "`"a [defendant's] chances of receiving a fair trial have been irreparably damaged."'" (People v. Ayala (2000) 23 Cal.4th 225, 282 [96 Cal.Rptr.2d 199 682, 1 P.3d 3].) Here, Gutierrez's volunteered remarks regarding defendant's phone calls were brief and ambiguous. The court did not abuse its discretion in concluding that any prejudicial effect could by cured by an admonition. Further, we note that as part of defendant's trial strategy, he later established his criminal history and recent incarceration through his own testimony. He claimed he took the victim's car because he had recently been released from prison and his values were poor. Defendant admitted that he threw the gun and ammunition from the car during the police chase and chose to explain that conduct by acknowledging that he was on parole and did not want to get caught with a gun. Defendant asserts that this evidence came in after Gutierrez's testimony and the trial might have proceeded differently but for her remarks. Given the limited nature of those remarks, however, his argument is not persuasive. 2. Asserted Doyle Error Defendant contends the prosecutor committed error under Doyle v. Ohio (1976) 426 U.S. 610 [49 L.Ed.2d 91, 96 S.Ct. 2240] (Doyle), during her cross-examination of defendant and in her guilt phase argument. Specifically, defendant complains the prosecutor improperly questioned his failure to inform the police or prosecutor of his alibi before trial. a. Background At trial, defendant presented an alibi defense that he had never mentioned during his several statements to Detective Castillo. According to testimony, Fred Rose was shot between 6:00 and 6:30 p.m. on January 23, 1992. Defendant testified that after using Rose's ATM card on that date, he tried unsuccessfully to locate a friend in Reseda, and then drove to East Los Angeles to visit Silvia Gomez. He arrived at the home of Gomez's mother about 6:00 p.m. and stayed until 8:00 p.m. He then drove through Los Angeles and Hollywood before continuing to Bakersfield. In his interviews with Detective Castillo, defendant never mentioned his visit with Silvia Gomez. After waiving his Miranda rights, defendant was interviewed twice. Defendant testified that "everything" in his first interview was false and stated, "I would have told them the moon was blue to throw them on a wild goose chase." He told Castillo he got in Rose's car for the first time in Bakersfield and spent no more than 10 minutes in it. Defendant claimed he had not been to North Hollywood for three and a half years. Defendant admitted that he lied in the second interview as well. He testified he was going to tell the officers the truth, but changed his mind. He 200 stated: "I said the hell with them. Let these bastards do their own homework." He initially told Detective Castillo that his mother dropped him off in Lancaster where he worked at construction sites until about 4:00 p.m. After eating at McDonald's, he got a ride from a construction worker to Mojave and hitchhiked from there to Bakersfield, arriving that night. After Detective Castillo confronted defendant with the Chevron credit card receipt and said he had been identified in a photographic lineup, defendant gave yet another explanation of events. In this version, defendant, while walking out of Lancaster on the Sierra Highway, saw the Oldsmobile with the keys inside and took it. He found the gun, wallet and credit cards in the car. He stopped at the ATM for money and "wanted to go to East L.A." to "visit some of my homeboys." Defendant testified that he did not know he had an alibi until he later learned when Rose was shot. Defendant claims that in certain exchanges during cross-examination, the prosecutor improperly used his post-Miranda silence to impeach his alibi. He points to several exchanges with the prosecutor, including the following colloquy: "Q. Do you enjoy being in jail? "A. No, I do not. "Q. Can you give us an explanation why you did not tell Detective Castillo that you were somewhere else [at the time Rose was killed]? "A. Because he probably would not have believed me at that point in time. "Q. Did you even try? "A. I figured there was no use even trying with him. "Q. Why would you figure there is no use even trying? You gave him all kinds of other stories you wanted him to believe. "A. Because... I did not know exactly what time that murder happened. I did not know exactly where I was at that point in time. "Q. Well you could have done the exact same thing. Just told him everything you did the whole day. 201 "A. I imagine I could have done that, but I didn't. "Q. Why not? "A. I wasn't into helping him along with his investigation. He was trying to get me. "Q.... [T]his investigator is trying to find out who committed a murder. You're his only suspect. If you knew you didn't commit the murder, why would you care if you're helping him? It is helping yourself, isn't it? It's not helping him. It's helping you. "A. Past experience, every time I reach my hand out to help I get it slapped." A short time later, the prosecutor and defendant had the following exchange: "Q. Isn't it true, sir, you had many opportunitiesDetective Castillo gave you opportunity after opportunity after opportunity to tell him where you were that entire day? "A. Yes. "Q. You never did, did you? "A. No, I did not. "Q. And in the year and eight months since this murder you have been in jail, correct? "A. Yes, I have. "Q. How many times have you seen him in the courtroom? "A. Numerous. "Q. Have you ever once tried to say, `Detective Castillo, it wasn't me?' I mean, by now you have got the time of the murder, right? "A. Yes." When the prosecutor asked why defendant did not tell Detective Castillo that Silvia Gomez could explain his whereabouts at the time of the murder, 202 defendant replied, "I didn't figure it would do any good at that point. Especially after the prelim." Defendant also stated that he was serving a one-year sentence for a parole violation at that time. The prosecutor asked, "So you figured, `I might as well stay in jail because I'm going to be doing this on a violation anyway.' Is that what you're telling us?" Defendant answered yes. The prosecutor then asked defendant why he did not contact Castillo about his alibi when the one-year sentence was completed. Defendant replied that he had told his attorney about his alibi. The prosecutor stated, "I'm not talking about your attorney. Talking about you." The prosecutor asked why defendant had not telephoned Castillo. Defendant replied that he "didn't figure at that point it would do any good." The prosecutor asked defendant why he had not spoken to her about his alibi during the numerous court appearances in the case. Defendant replied that the
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Why? Because they really, really want those tax cuts for the rich, and they are apparently willing to see any norm or institution fall in order to get them. And the planet too, if need be. And the Democrats? Oh-oh! They have been voted completely out of power. So can it get any darker? Well, yes, a lot. We may live to see this worst of all worst-case scenarios play out over the next few years, and we can throw in a blundered-into war while we’re awful-izing here. AD However. I am going to return to Plan B, which is not so unrealistic as it might seem. Because if history has taught us anything, it’s that it loves to deliver the unexpected. Best-laid plans of mice and monsters, you know. AD The remnant pieces of American democracy are not inconsiderable. The nation has a long history of slow, agonizing progress toward inclusion, reason and overcoming our worst impulses. The vast numbers of Americans with better value systems than our president-elect are still here. It is not only those with grudges against minorities who are capable of making their voices heard. The facts of the world do not disappear, and neither does the arc of history, even though it currently looks more like a tangle of knotted string than a bow. I expect Trump to do his damnedest, and I chose that word deliberately, to twist this nation to satisfy his own insatiable ego needs. And he now has staggering power at his little fingertips.New-Look Lines Rolled Out BOSTON, MA – After the Boston Bruins scored just one goal against the Washington Capitals last night for the third time in four games, Head Coach Claude Julien unveiled a brand new look at practice Friday at TD Garden. At first sight the changes look drastic, but it’s not unfamiliar territory for anybody according to Campbell. “Something we as players are used to throughout our career is having to adapt and play with different players,” Campbell said. “If you look at the changes, they look drastic but they’re really not. “Marshy and Thorty and I played together almost half a season last year and at one point or another everyone’s played with everybody in this room. We look at it as a change, and hopefully it jumpstarts some offense.” While Brad Marchand has struggled to register a point in the series, Campbell felt that No. 63 could benefit from playing on his line. “Just playing with two great players builds your confidence,” Campbell said jokingly. On a more staid note, Campbell said that his line’s simple play may help generate more on the score sheet. “A lot of time if you’re struggling to score or struggling in any area of your game anyone will tell you go back to basics and keep it simple,” Campbell said. “And that’s what Thorty and I always do. We try to play high energy and be physical and in playoff hockey, physicality is key and sometimes the best recipe for a change for some offense is to keep it simple.” Like Marchand, Seguin is without a point thus far in the series and was asked if he thought a message was being sent with the line change. “I don’t know,” Seguin said. “I think when you’re not scoring goals as a team, what’s the thing you do? You switch things up, you get guys playing with different guys and playing with Kells [Kelly] and Pou [Pouliot], obviously they’re two great players so hopefully we can pop a couple.” After last night’s loss, David Krejci freely used the word frustration to describe his attitude after the game. But Seguin said he felt it’s more of a determination to score, rather than a frustration. “When you get 45 shots on net, and when you look at the actual scoring chances they’re pretty equal, that’s not very acceptable,” Seguin said. “We have to generate more scoring opportunities, kind of like Timmy [Thomas] said getting more guys to the net and banging bodies around the crease.”Sibship characteristics and risk of allergic rhinitis and asthma. Studying associations between sibship characteristics and allergic diseases in detail may contribute clues to their etiology. The authors studied associations between sibship characteristics and risk of self-reported allergic rhinitis and asthma among 31,145 pregnant women participating in a nationwide study in Denmark during 1997-2000. Increasing sibship size was associated with a decreased risk of allergic rhinitis and asthma with allergic rhinitis but not with asthma without allergic rhinitis. The protective effect of having older siblings was stronger than the protective effect of having younger siblings for both allergic rhinitis and asthma with allergic rhinitis. There was no association between interval to closest older or younger sibling and risk of allergic rhinitis or asthma with allergic rhinitis, while the risk of asthma without allergic rhinitis increased with intervals of 2 or more years compared with less than 2 years to the nearest older sibling. The protective effect of having siblings on the risk of asthma with allergic rhinitis could be explained by a protective effect of siblings on the risk of allergic rhinitis alone. In conclusion, our findings suggest that different etiologic mechanisms are involved for allergic rhinitis and asthma with respect to the effect of sibship characteristics. Furthermore, the findings that allergic rhinitis was associated with the number of younger siblings but not with the age interval to younger siblings support the hypothesis of an influence of postnatal mechanisms and suggest that these mechanisms may not necessarily be operating only in early life.A personal computer (PC) display typically shows a stack of application windows corresponding to different types of work a user may be doing (for example, word processing, e-mail, spreadsheet, video, etc.), with the currently active application window at the top of the stack, thus appearing closest to the user. When a user changes from one activity to another, these windows are re-composed into a new desktop image, bringing a new application window to the fore. Future PC product plans call for composing the application windows using three-dimensional (3D) animation techniques to provide the user with a richer visual experience where the animations move smoothly. To make the animations move smoothly, they must be free from jerkiness that can be caused if the desktop image is not composed rapidly enough. Unfortunately, composing a PC desktop image at sufficiently high rates requires excessive amounts of graphics memory bandwidth, which increases costs to levels that may be unsustainable in products targeting the mobile and low cost PC markets. Conventionally, to deal with inadequate computational or memory resources, frames are simply dropped. Since image information representing original content is discarded, the result often is animation that is jerky in appearance, similar to animated video often seen on personal computers today. This frame skipping may cause the video frame-rate to drop below the frame rate desired to perceive smooth motion. As a result, low bit rate video may at times look jerky to the user.Hrithik Roshan asks Karan Johar to shoot 'K3G' sequel in space! Actor Hrithik Roshan, who played the role of Bollywood superstar Shah Rukh Khan's younger brother in Karan Johar's 'Kabhi Khushi Kabhie Gham...', has asked the filmmaker to shoot the sequel to the 2001 drama film in space. Karan posted on Twitter a video of 1962 science fiction animated children's television show “Fireball XL5”, which followed the missions of spaceship Fireball XL5, commanded by Colonel Steve Zodiac of the World Space Patrol. “'Fireball XL5' - Start and Theme Song - YouTube who remembers this? #childhoodtelevision,” the “My Name is Khan” director captioned the video.The applicants proposed to design, construct, and test a prototype scanning device capable of reconstructing regional, optical absorption in three dimensions within the human breast. The device will consist of an array of sixteen,.25" diameter transducers aligned along a 60 degree, 15 cm radius arc. This arc of transducers will be scanned axially to acquire a set of photoacoustic "projections" over a little less than 2p steradians. Photoacoustic image reconstruction will be performed using a modified, inverse Radon transform. Imaging performance will be evaluated in terms of contrast/noise and spatial resolution as a function of irradiating energy (infrared and microwave) and depth within a tissue-mimicking phantom. Based on the Phase I results, specifications will be determined for a clinical prototype photoacoustic scanner, to be designed, constructed and tested in Phase II.29-30 October 2016 - Analog Forum - Krefeld - Germany We participated to the Analog Audio Association Forum in Krefeld (Germany) with our Tempesta 20, presented by Thomas H. Diehl producer of the Holz-Akustik racks.Here You can find more information about the show, and here You can download the official flyer. Thomas H. Diehl was really surprised about the quality of the presentation. And this is his comment about the show (in German):Terms and Conditions please read carefully and feel free to contact us with any questions you may have This web site is owned and operated by Myon Life Ltd who are completely dedicated to your total satisfaction. By accessing this site, you are acknowledging that you have read, understand and agree, without limitation or qualification, to be bound by these terms and conditions. This site is designed to make your shopping experience as safe and enjoyable as possible. If you have any questions in regards to our products or the website, you can contact us at
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8069, 673, 12367, 272, 187, 14094 ]	everyone. A productivity system that doesn't make you feel good about your daily life is not be sustainable in the long run. It doesn't matter how effective it is, that's not a life you want to be living. What makes you feel better about your daily life will depend on your temperament. The author of this blog post found that GTD resulted in his feeling like he had a never-ending river of stress ahead of him. GTD failed for him. Another example where GTD fails is for anyone who is doing sustained creative work. As Paul Graham describes in [http://www.paulgraham.com/makersschedule.html](http://www.paulgraham.com/makersschedule.html), it is very important for those people to have large blocks of time set aside for focused work. GTD's focus on breaking things into simple tasks whose execution is routine is the antithesis of how work needs to be organized for a maker. That said, GTD is life-changing for many people. If it works for you, by all means do it. But don't make the mistake of trying to convert everyone else to it. It isn't always right. ~~~ luketych GTD IS for everyone. All GTD is, is acknowledging how our brains function at a very fundamental level, and then building a trustable system around that. Why can't create tasks work in GTD? GTD methodology doesn't say that you HAVE TO break everything up into 2-minute chunks. It can be 2 hours set aside for creativity. Saying "X doesn't work for everyone" sounds nice, as does "everything in moderation." But I get skeptical when someone uses "everything in moderation" to excuse their smoking habit, or "___ is NOT for everyone". Hundreds of years ago I'm sure there were people arguing that "reading and writing is not for everyone." Eating vegetables is not for everyone, etc. ~~~ orblivion I get skeptical when people are so enthusiastic about some newfangled anything that they compare it to reading and eating vegetables. GTD _could_ be that good but it's an extraordinary claim and it deserves to be scrutinized accordingly. ~~~ luketych As you should. It's not my job to sell Gtd to you. But I have to challenge your emotional intelligence if you let other peoples' enthusiasm cloud your own view. ~~~ orblivion I base it off my my own experience getting enthusiastic about things. ~~~ luketych lol, but isn't your own enthusiasm at least somewhat affected by other peoples' enthusiasm or lack there of? ~~~ orblivion Sure. I'm not sure what your point is, maybe my point wasn't clear. I'm just saying that I've been in the position at least once where I was excited about something and I overblew its potential in solving problems. So when I see others doing it, I can relate, but know that they're likely clouded in their judgement. ------ moron4hire I don't think that was a failure of GTD. I think that was a failure to understand your own limitations and what you're realistically going to be able to accomplish in any given timeframe. It really sounds like a fundamental failure to _properly_ understand GTD. If you actually read _the book_ \--rather than the BusinessInsider, et. al. listicles summarizing it--Allen makes the point that the most important feature of any task tracking system be that it is not cumbersome. All else be damned. If whatever system you're using to keep track of what you need to do is getting in the way of keeping track of what you need to do, then it is no good. He also makes the point that nobody is meant to do everything in the book. The book is meant to be a cookbook, you are meant to try different things in the book up to the point of gaining control of your work _and then put the book down_. You're supposed to stop reading GTD when you start to get things done. Don't mess with a good recipe. I keep a single sheet of paper as my TODO list. If it doesn't fit on the paper, it doesn't go on the list. It's one list for both work and personal issues, because I only have one life, I can't clone myself and work on two lists in parallel. I scratch things off and reuse the paper until it's full. I then rewrite the list on a new sheet of paper, with items that have gone undone for a long time naturally bubbling up to the top of the list. And if something has been ignored at the top of the list for a long time, I just throw it away. If it didn't get done in the last month, clearly it's not that important. If it were more important, I would have made the time to do it. Get better about throwing away your emotional baggage. ------ VladimirGolovin I too find GTD unsuitable for creative work, mostly because it doesn't handle open-ended, non-tickboxy tasks well, though I can't say that I was using GTD properly -- for example, I couldn't bring myself to do weekly reviews. Overall, GTD felt like it requires too much willpower to run. Have you tried Mark Forster's Autofocus or Final Version Perfected systems? If not, you owe yourself a try. The systems, at their core, are very simple: 1\. You have a long list of tasks (the same 'ubiquitous capture' principle as in GTD and other systems) 2. You scan the list for tasks that'stand out' for you as 'ripe' to be done / worked on. This means that you're mentally ready to do these tasks. 3. Work these tasks for as long as you feel like. It's not necessary to finish these tasks. 4. After you've dont with a task, you either cross it off the list, or re-append it to the end of the list. I found his systems much more tolerant of creative work, and much less willpower hungry. A downside of these systems is that they're not capable of handling tasks with start / due dates. Also, regarding de-cluttering todo lists, I firmly believe that: 1\. ALL your tasks and actionable thoughts must be captured in your system. 2. Your _current_ todo list must only show items that you are ready to do _right now_, at the moment. For example, your todo list shouldn't show the task 'Vacuum the floor' if you're not at home. Therefore, there must be ways of de- cluttering your todo list that allow you to defer the tasks until your external (or internal!) conditions are more conducive to working on these tasks. (I got fed up with the inability of most todo apps to do the above, so I'm working on my own todo app). ~~~ sametmax This is actually a perfect application of GTD. Most people don't realize how flexible GTD is, and feel like everythin must be well define, and have a time frame. It doesn't. You have the reviews for that. You have the "projects" list for that. You have "waiting for" for that. "Spending time on 'creative job x'" is actually a perfectly good task name to add to your "project" list. In your daily review, you scan the one you want to work and and you add the ones you feel like to your "next" list. GTS itself must NEVER be applied as-is, and should be adapted to your line of work, rythm, life style and personnalité. And it's very good at it. ~~~ VladimirGolovin I guess I couldn't stomach the idea that GTD mandates dedicated review stages, while in Autofocus / FVP and in my own system review is a continuous process. Ideally, I'd like to have the ability to do'makeshift reviews' per-task, and on different timescales. For example, if I don't feel like doing Task X today, I'd defer it for 5 days, so its next review will happen in 5 days. But if there's another task I'll probably want to do tomorrow, I'd defer it to tomorrow, so I'll review it tomorrow. On the other hand, I do seem to have a de-facto review stage. In the morning I usually go through my task list in Wunderlist (which I hate but use daily) and mark items I'd like to do today. But this is probably because Wunderlist doesn't offer a proper Defer / Hide Until ability that doesn't screw with tasks' due date. (And I have a recurring task 'Review all items', a relic from a bygone era when I attempted to do GTD properly.) ------ rbrogan From what I am reading, the author is saying they are effectively time slicing their
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3440, 15, 187, 187, 32197, 342, 8438, 473, 457, 51, 454, 413, 13, 15404, 26512, 246, 7760, 411, 297, 1559, 1074, 275, 253, 9243, 26650, 457, 84, 14098, 15, 473, 8, 51, 454, 413, 556, 644, 1048, 2330, 342, 253, 5661, 285, 1965, 87 ]	, the GAF domain of Hik2, which is found in class I Hik2s, might be involved in perceiving additional signal(s) such as redox or it might bind small ligand(s) required to regulate its autophosphorylation (Allen [@CR2]). Indeed, the Hik2 homologue in higher plants has been shown to bind the PQ analogue DBMIB with a K~d~ value similar to that of other quinine-binding proteins (Puthiyaveetil et al. [@CR33]); it also forms a quinone adduct (Ibrahim et al. [@CR18]). Figure [11](#Fig11){ref-type="fig"} proposes a working model of signal perception mechanism of Hik2. In the absence of increased salt concentration or redox stresses, the Hik2 is autokinase-active and transfers phosphoryl groups to the response regulators Rre1 and RppA, while Phospho-Rre1 activates genes coding for light-harvesting phycobiliproteins. However, in the presence of salt/osmotic stress, the active hexameric form of Hik2 is rearranged into the inactive tetrameric form. Rre1 and RppA, therefore, remain in their unphosphorylated states. As a result, Rre1 can no longer act as a repressor of salt/osmotic tolerance genes, in turn releasing the repression of their transcription. We are unable to determine the precise symmetry of the oligomeric forms described here. For example, the hexamers could be either trimers of dimers of 32-point group symmetry or hexamers of hexagonal symmetry (point group 6). Similarly, the tetramers could be dimers of dimers (point group 22), or tetramers of tetragonal symmetry (point group 4), and tetragonal tetramers may assemble into octamers as dimers of tetramers (point group 42). Conversion between hexamers and tetramers is likely to involve only oligomers of the aforementioned symmetries. This conversion between oligomers would be possible if conformations of the subunits change during the transition. The molecular basis of a mechanism by which elevated Na^+^ concentrations trigger recombination of hexamers into tetramers could therefore be twofold. Na^+^ may interfere with salt bridges that stabilise intersubunit interfaces at low salt concentrations. In addition, Na^+^ may induce conformational changes in the protein subunits thus leading to the disruption of intersubunit interactions in the hexamers and favouring the formation of new protein-protein interfaces that result in inactive tetramers.Fig. 11Proposal for a Hik2-based signal transduction pathway in cyanobacteria. The hexameric form of Hik2 is autokinase-active, and the oligomeric state of Hik2 is regulated by signals from Na^+^ and the photosynthetic electron transport chain. The active hexameric form of Hik2 is converted to an inactive tetramer upon salt stress Hik2 is of special interest because of the presence of its homologue in all known cyanobacteria as well as in chloroplasts (Table [2](#Tab2){ref-type="table"}). In eukaryotes, the homologue of Hik2 is termed CSK, a protein that is encoded in the nucleus and synthesised in the cytosol for post-translational import and processing in chloroplasts (Puthiyaveetil et al. [@CR32]; Puthiyaveetil et al. [@CR35]). CSK couples the redox state of the photosynthetic electron transport chain to chloroplast gene transcription (Puthiyaveetil and Allen [@CR30]) by acting on plastid transcriptional regulators (Puthiyaveetil et al. [@CR33]; Puthiyaveetil et al. [@CR34]). It will be important to determine whether the oligomerisation that we propose as the basis of regulation by sodium ions is also a mechanism that extends to redox regulatory control of the activity of all Hik2 proteins, including CSK. The oligomeric states of Hik2 and CSK may determine their sensitivity and the amplification gain (Koshland et al. [@CR21]) of the cell's response to changes in both sodium ion concentration and redox state of photosynthetic electron carriers. IMI thanks Queen Mary University of London for a graduate teaching studentship. LW thanks the China Scholarship Council (CSC) and Queen Mary University of London for financial support. SP held a Leverhulme Trust early-career post-doctoral research fellowship. JN is grateful for the continued support of the JST CREST Grant Number JPMJCR13M4, Japan. JFA acknowledges the support of research grant F/07 476/AQ and fellowship EM-2015-068 of the Leverhulme Trust. Conflict of interest {#FPar14} ==================== The authors declare that they have no conflict of interest. [^1]: Handling Editor: Peter Nick Q: Python pass argument to constructor by reference import pandas as pd class MyClass(): def __init__(self, df): self.df = df def edit(self): self.df = self.df[~self.df['numbers'].isin([2,4,6,8,10])] df = pd.DataFrame([1,2,3,4,5,6,7,8,9,10], columns=['numbers']) obj = MyClass(df).edit() print df I am expecting print df to print the dataframe which has been reassigned after the filteration function. But this stil prints the dataframe which is before the edit function modify it. How can my outer variable still track the changes happend to the df inside class A: How can my outer variable still track the changes happend to the df inside class The way you are trying to do this, namely by reassignment, it's impossible. Names do not "see" the reassignment of other names (imagine the catastrophe if they did). Your only chance without reassigning df here is to mutate the dataframe. All you currently do is to create a new object and reassign self.var. The var outside of your class does not care about that and still points to the old object. Of course the sensible thing to do would be to just reassign df to the return value of some function or method, i.e.: def compute_new_df_from_old_df(df): return df.foo()[bar] df = <some dataframe> df = compute_new_df_from_old_df(df) Recipe, Information, how-tos and much more.. Chocolate Chip Muffins Discuss a chocolate sweetheart’s fantasy, these Chocolate Chip Muffins are certain to satisfy the chocolate significant other in your life. Chocolate Chip Muffins are brought up a score with the expansion of chocolatechips blended into the hitter. At that point, more chocolatechips are sprinkled on upper just before they go into the stove. The result is the perfect mixture of chocolate, and well more chocolate. For Chocolate Chip Muffins Lovers What I cherish about these little Chocolate Chip Muffins is that they aren’t excessively sweet. Don’t get me wrong, in any case they have little sweetness to them then again; they are not cake or cupcake like sweet. Furthermore when they leave the stove, they are super damp and simply ideal for a unique breakfast. These Chocolate Chip Muffins are best served new out of the stove, as we did get to be mindful of they tend to lose a portion of the wetness when they are consumed as remains a day or two later. What you need to cook Chocolate Chip Muffins? On the off chance that you are searching for a simple formula for Chocolate Chip Muffins, this totally possesses all the necessary qualities. You don’t even need to get out your blender. All you will need to make these without any preparation is several enormous dishes, and huge wood spoon. OK, it doesn’t need to be a wood spoon; however that is the thing that I use for the reason that it’s my top pick. Doesn’t everyone have a most loved kitchen utensil? Simply take a gander at the chocolate overflowing from these biscuits. Yum! Wouldn’t precisely call these sound however serve some new foods grown from the ground close by them and it may help ease any blame you have over serving chocolate for breakfast (which I am never contradicted to!). How to make Chocolate Chip Muffins? Prep Time: 7mn Cook Time: 20mn Total Time: 27mn Ingredients 1 3/4 measures broadly functional flour 1/2 mug sugar 1/4 mug tan sugar 1/4 mug unsweetened cocoa powder (Dutch process in the event that you have it)Womblife Womblife is an album by American fingerstyle guitarist and composer John Fahey, released in 1997. It was one of three releases by Fahey that year. History Womblife continues John Fahey's career resurgence, again bearing minimal resemblance to his earliest work. It incorporates sound collages and experimental music. Working with Jim O’Rourke, Fahey taped Womblife in the younger musician’s bedroom. O'Rourke has been long associated with the experimental and improv
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Na rua, Marta via como os olhos de Dominika saltavam entre os rostos das pessoas e as entradas dos prédios, ao longo do passeio, do outro lado da estrada, usando movimentos normais para disfarçar os olhares constantes. Quando estavam sentadas juntas num café, havia o vislumbre de intuição gratificante, a sugestão de jovialidade, o sorriso brilhante. Marta identificou facilmente o uso quase inconsciente que Dominika fazia da beleza – olhos, sorriso, corpo – nas suas relações com as pessoas. E, quando falavam, Marta reconheceu as técnicas de conversação e extração de informações que Dominika usava. Uma criatura extraordinária, pensou Marta, e operacional! Beleza, cérebro, habilidade e olhos azuis incandescentes. Era evidente que ela sabia o seu dever, amava o seu país, mas também havia algo abaixo da superfície, uma corrente subterrânea que borbulhava, invisível. Orgulho, raiva, desobediência. E algo mais, difícil de definir, um lado secreto, uma paixão pela rebeldia, como se namorasse com o perigo. Marta perguntou-se quanto tempo demoraria esta jovem, com o seu olhar perspicaz e instintos naturais, a perceber que o trabalho do Centro era pokazuhka, algo feito apenas pelas aparências, para inglês ver. O rezident Volontov era um exemplo extremo da ética laboral, o tipo de funcionário que geria o KGB e o Kremlin há setenta anos. Começaram a sair juntas da embaixada ao final do dia, parando num bar da zona para um copo de vinho e uma fatia pecaminosa de tarte de caviar carregada de crème fraîche e queijo. Falavam da família, de Moscovo, das suas experiências. Dominika não mencionou a Escola de Pardais. Marta ria-se e fazia rir Dominika, e caminhavam de braço dado pelo passeio ao anoitecer. Uma noite, num bar, depois de despachar rapidamente um alemão nojento que não as deixava em paz, Marta contou a Dominika a história da sua vida, a sua carreira como Pardal. Estava orgulhosa de ter servido o seu país; não pensava nos anos infernais do KGB. Não se mostrava minimamente envergonhada de quem era nem daquilo que fizera. O lábio inferior de Dominika tremeu, olhou para a amiga e começou a chorar silenciosamente. Foi uma longa noite, depois disso, mas Marta ficou a saber tudo sobre ela. A missão contra Nate, o tio Vanya, a Escola de Pardais, o francês Delon, até Ustinov. As palavras brotaram de Dominika numa torrente. Não pensaram em manipulações nem em extração de informações. Daí em diante as duas mulheres ficaram, simplesmente, amigas. Noite após noite, calma e reservada, Marta escutava e pensava: Céus, como os vlastiteli, os patrões, espremeram tanto desta rapariga em tão pouco tempo. Contudo, Marta via força em Dominika, e via algo mais. Marta desconfiava de que a exposição de Dominika ao jovem e descontraído agente americano da CIA estivesse também a criar reações mais profundas. Dizê-lo seria insinuar que Dominika não conseguia cumprir corretamente a sua missão, portanto Marta não disse nada. – Não sei – disse Dominika. – Ele é arrogante, é brincalhão, não gosta da Rússia, ou pelo menos não nos dá grande crédito. O tio Vanya acredita que ele é um operacional desesperado. – Parece ser desagradável – disse Marta. – Mas isso deve tornar mais fácil para ti trabalhar contra ele... até dormir com ele... para obteres aquilo que pretendes. – Acendeu um cigarro e olhou para Dominika, recostada no banco. Iam no terceiro copo de vinho. – É mais frustrante do que desagradável. Mas simpático. – Suspirou. – Tenho de dizer ao Volontov quando achar que ele está operacional, distraído. Querem apanhá-lo com o seu informador. – Dominika estava a sentir os efeitos do vinho. – E conhece-lo suficientemente bem para isso? – perguntou Marta. – Conseguirás perceber? Dominika afastou uma madeixa de cabelo da testa. – Acho que já percebi... quer dizer, sei que sim – respondeu ela. – E correste a informar o coronel Volontov – disse Marta. Já sabia o que estava a acontecer. – Não propriamente – confessou Dominika. – Disse-lhe que continuaria atenta. – E não o informaste de que desconfiavas que o teu jovem americano estava a entrar em ação. – Ele não é o «meu jovem americano» – disse Dominika, de olhos fechados. – Mas suspeitas que é isso que se passa, e o Volontov perguntou-te diretamente e tu não disseste nada, correto? – perguntou Marta, inclinando-se para Dominika. – Abre os olhos, olha para mim. Ela abriu os olhos. – Correto. Não disse nada. – Fechou os olhos. Marta bebeu um gole de vinho e pensou, com alguma frieza, que Dominika não só cometera traição contra o Estado – dizer traição contra a Duma parecia ridículo – ao não transmitir as informações e ao mentir a respeito delas, como também fizera com que, nessa noite, Marta se tornasse igualmente culpada de traição ao tomar conhecimento do crime. Estendeu o braço e apertou a mão de Dominika. – Tens de ter cuidado – disse. Marta tinha dedicado a sua vida ao Estado, ignorara durante anos os seus excessos e contribuíra pessoalmente para a desgraça de homens cujo único pecado fora sucumbir aos prazeres da carne. No entanto, por dentro, há muito que rompera com esses filhos da mãe. Sabia a situação em que Dominika se encontrava. As bestas, pensou, esvaziarão completamente esta rapariga bela e inteligente e depois livrar-se-ão dela. E, se aquilo que ela estava a fazer afetasse, ainda que remotamente, Vladimir Putin, seria mortalmente perigoso. O conhecimento de Dominika era como um saco de cobras fechado com um nó – seguro, de momento, mas era melhor não bater com ele contra a parede. A curta visita de MÁRMORE a Helsínquia foi um êxito em muitos aspetos. Primeiro, MÁRMORE encontrou-se e fez progressos significativos com Trunk, o ministro do Comércio, estabelecendo assim de forma indubitável a necessidade continuada de manobrar o extravagante canadiano. Em segundo lugar, três noites de reuniões até de madrugada com Nate, no Hotel GLO, já tinham produzido oito relatórios de informações de nível elevado (com material suficiente para, possivelmente, mais trinta e sete) sobre as operações do SVR na Europa e na América do Norte. Terceiro, MÁRMORE fornecera o nome de um comissário assistente na Direção de Política E
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See also 7. References 7. DYNAMIC INTEGRATION: DYNAMICS \| Theory of Cargo and Membrane Trafficking 1. Abstract 2. Introduction 3. Theory of the Endosomal Network 4. Regulation of the Microscopic Processes 5. Relation to Kinetics of Total Cargo Pool 6. Implications for Cargo Sorting 7. Conclusion 8. See also 9. References 10. Further Reading 8. DYNAMIC INTEGRATION: DYNAMICS \| Transcription Factor Networks 1. Abstract 2. Introduction 3. Local Properties of GRNs 4. Motifs 5. Global Properties of GRNs 6. Conclusions 7. See also 8. References 9. Further Reading 3. Vertical Integration 1. Modeling 1. VERTICAL INTEGRATION: MODELING \| Vertical Integration 1. Abstract 2. Introduction 3. The Multiple Time and Spatial Scales Associated with Cellular Biology 4. Approaches for Linking Scales in Multiscale Models: 'Top-Down', 'Bottom-Up,' and 'Middle-Out' 5. Mathematical and Computational Representations of the Components of a Multiscale Model 6. Assembling Multiscale Modeling 7. Software for Multiscale Modeling 8. Applications of Multiscale Modeling and Two Case Studies 9. Challenges Associated with Multiscale Modeling 10. Summary 11. Conclusions 12. See also 13. References 14. Further Reading 2. VERTICAL INTEGRATION: MODELING \| Computational Approaches for Multiscale Modeling 1. Abstract 2. Glossary 3. Introduction 4. Multiscale Modeling 5. Discussion 6. Acknowledgments 7. See also 8. References 9. Further Reading 10. Relevant Website 3. VERTICAL INTEGRATION: MODELING \| Cardiac Modeling 1. Abstract 2. State-of-the-Art in Cardiac Cell Modeling 3. Human Models of Cardiac Cell Electrophysiology 4. Modeling Variability in Cardiac Cell Electrophysiology 5. Whole Organ Cardiac Modeling 6. Conclusions and Outlook 7. References 8. Relevant Website 2. Applications 1. VERTICAL INTEGRATION: APPLICATIONS \| Mathematical Approaches to Studying Inflammation 1. Abstract 2. Introduction 3. A Simple Mathematical Model Capturing the Resolution of Inflammation 4. Current Mathematical and Computational Models of Inflammation 5. Early Events, Leukocyte Responses to Bacteria 6. Inflammatory Cytokines, TNF-Therapy 7. Tissue Damage and Wound Healing 8. Inflammation and Progression to the Immune Response 9. Conclusions and Future Challenges 10. See also 11. References 2. VERTICAL INTEGRATION: APPLICATIONS \| Angiogenesis 1. Abstract 2. Glossary 3. Vascular Evolution 4. Developmental Vasculogenesis 5. Capillary Structure 6. Primary Factors Controlling Angiogenesis 7. Hypoxic Induction of Angiogenesis 8. Sprouting Angiogenesis 9. Intussusceptive Angiogenesis 10. Arterial and Venous Vessels 11. Summary 12. References 3. VERTICAL INTEGRATION: APPLICATIONS \| A Review on Various Mathematical Modeling Approaches for Wound Healing 1. Abstract 2. Wound Healing and the Need for Modeling 3. Evaluation of Several Mathematical Approaches 4. Conclusions 5. See also 6. References 4. VERTICAL INTEGRATION: APPLICATIONS \| Multiscale Analysis of Morphogenesis 1. Abstract 2. Introduction 3. Vertical Integration 4. Analyzing Cell Behavior 5. Mathematical Models for Studying Collective Cell Behavior 6. Examples of Vertical Integration Studies 7. Conclusion 8. Acknowledgments 9. References 10. Further Reading 5. VERTICAL INTEGRATION: APPLICATIONS \| Neurogenesis in the Adult Brain 1. Abstract 2. Introduction 3. Historical Perspective 4. Identity of Adult NSCs 5. Cell Proliferation in the SVZ 6. Neuronal Migration in the RMS 7. Neuronal Differentiation in the Olfactory Bulb 8. Potential Functions of Adult Neurogenesis 9. Potential Applications 10. Conclusion 11. References 12. Further Reading 4. Horizontal Integration 1. Networks 1. HORIZONTAL INTEGRATION: NETWORKS \| Understanding of 'Networks' _In Vitro_ and/or _In Vivo_ 1. Introduction 2. Networks in Cancer 3. Concluding Remarks 4. See also 5. References 6. Relevant Website 2. Omics 1. HORIZONTAL INTEGRATION: OMICS \| Connecting Evolutionary Genomics to Cell Biology 1. Abstract 2. Genomics for Old and New Questions 3. Case Studies: New Genes for Old and New Functions 4. Gene Traffic 5. Gene Regulatory Networks 6. Cell Division 7. Protein Traffic 8. Perspectives 9. Acknowledgments 10. References 2. HORIZONTAL INTEGRATION: OMICS \| Transcriptomics 1. Abstract 2. Glossary 3. Introduction 4. Evolution of High-Throughput Transcriptomic Technologies 5. Exploring the Interactive Transcriptome 6. New Technologies for mRNA Transcriptomics 7. Integrating Transcriptomics with Other Omics 8. Conclusion 9. See also 10. References 3. HORIZONTAL INTEGRATION: OMICS \| The Advent of Mass Spectrometry-Based Proteomics in Systems Biology Research 1. Abstract 2. Systems Biology and Proteomics 3. Liquid Chromatography-Coupled Tandem Mass Spectrometry 4. Systems Biology Application for High-Throughput Proteomics 5. Outlook 6. Acknowledgments 7. See also 8. References 4. HORIZONTAL INTEGRATION: OMICS \| Phosphoproteomics: Approaches, Developments, and Challenges 1. Abstract 2. Introduction to Posttranslational Modifications 3. Protein Phosphorylation 4. Phosphopeptide Enrichment 5. Large-Scale Phosphoproteomics Strategies 6. Phosphopeptide Fragmentation 7. Quantitative Phosphoproteomics 8. PTM Cross Talk and PTM Coding 9. Challenges in Phosphoproteomics 10. Conclusions 11. See also 12. References 5. HORIZONTAL INTEGRATION: OMICS \| Interactomes - Scaffolds of Cellular Systems 1. Abstract 2. Introduction 3. Methods to Map Interactomes 4. Applications of Interactome Maps 5. Perspectives 6. See also 7. References 6. HORIZONTAL INTEGRATION: OMICS \| Metabolomics in Cell Biology 1. Abstract 2. Introduction 3. Conducting a Successful Metabolomics Study 4. See also 5. References 3. Analyses and Tools 1. HORIZONTAL INTEGRATION: ANALYSES AND TOOLS \| Network Modeling of Heterogeneous Datasets 1. Abstract 2. Introduction 3. Overview 4. Network Algorithms 5. See also 6. References 2. HORIZONTAL INTEGRATION: ANALYSES AND TOOLS \| Stochastic Analysis of Nongenetic Cell-to-Cell Heterogeneity 1. Abstract 2. Glossary 3. Introduction 4. Cell Signaling 5. Variability in Gene Expression 6. Single-Cell Analysis 7. Modeling and Analysis of Stochastic Data 8. Connecting Heterogeneity at Multiple Levels 9. Conclusion 10. See also 11. References 3. HORIZONTAL INTEGRATION: ANALYSES AND TOOLS \| Systematic Methods to Interrogate Genetic Perturbations and Map Phosphorylation-Dependent Signaling 1. Abstract 2. Acknowledgments 3. See also 4. References 4. HORIZONTAL INTEGRATION: ANALYSES AND
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3951, 1311, 740, 8562, 187, 187, 13569, 19416, 24365, 6521, 1566, 1712, 4538, 1348, 94, 187, 1013, 187, 187, 1231, 8671, 3786, 2529, 7241, 3951, 1311, 3011, 3725, 835, 12821, 5343, 3754, 497, 10370, 37313, 16119, 466, 291, 297, 1025, 327, 1388, 20, 313, 34691, 1186, 73, 10, 275, 253, 3361, 273, 16028, 30832, 15, 1294, 34847, 387, 337, 15, 17, 1186, 7913, 16, 1099, 1186, 34753, 273, 2133, 2801, 313 ]	for overnight at 4 °C. Finally, cells were washed three times with PBS and DAPI (1 µg/ml) was used for nuclear stain. Coverslips were mounted onto slides using 70% glycerol^[@CR57]^. Images were acquired using a laser scanning confocal microscope (Carl Zeiss LSM 510 META, Jena, Germany) equipped with a plan apochromat 63x oil/1.4 NA DIC objective, and 3x optical zoom over 63x objective (189 X). Immuno-histochemistry of ITGB8 and FAK {#Sec19} -------------------------------------- The immunolocalization study was done according to the earlier described method with some minor modification^[@CR61]^ ~.~ The 5 μm sections of tissue were deparaffinized overnight (12--15 hr) in xylene and allowed to rehydrate with subsequent changes of the gradient of ethanol (100%, 95%, 70%, and 50%) and distilled water for 10 min with two changes. Antigen retrieval was performed in sodium citrate buffer (10 mM, pH 6) for 20 min followed by the immuno-fluorescence method as described previously^[@CR10],\ [@CR57]^. Tissue sections were further blocked in 5% goat serum for 1 hr and subsequently, after washing with PBS, incubated overnight at 4 °C with the ITGBβ8, and FAK antibodies in 1:100 dilutions and normal rabbit IgG in 1/100 dilutions in 2% goat serum. For the immuno-fluorescence, anti-rabbit FITC conjugated antibody was incubated and counterstained with the Propidium Iodide (PI)^[@CR10]^. Slides containing tissue sections were dehydrated using ethanol gradient (50%, 70%, 90%, 100%) and absolute xylene. Finally, uterine tissue sections were mounted using either DPX or 50% glycerol and the image were captured using a phase contrast inverted phase contrast microscope (CKX41 Trinocular with Cooled CCD Camera Model Q Imaging MP5.0-RTV-CLR-10-C from Olympus, Tokyo, Japan). ITGB8 esiRNA transfection and FAK activity inhibition in the human endometrial cells (Ishikawa cells) {#Sec20} ------------------------------------------------------------------------------------------------------- Ishikawa cells (Human endometrial adenocarcinoma epithelial cell line) was a kind gift from Dr. Anila Dwivedi, Endocrinology division, (CSIR-CDRI, Lucknow, India) and was maintained in Minimum Essential Medium Eagle supplemented with 1% non-essential amino acids, and 2.2 gm/L sodium bicarbonate and 1% anti-mycotics and antibiotics supplemented with 10% fetal bovine serum. Cells were grown at 37 °C and 5% CO~2~ in humidified condition. JAr cells \[HTB-144, American Type Culture Collection (ATCC), Manassas, VA, USA\], a human choriocarcinoma cell line, were maintained in advanced DMEM/F12 supplemented with 10% FBS and 1% anti-mycotics and antibiotics grown at 37 °C and at 5% CO~2~ concentration in humidified condition. Ishikawa cells were seeded in a 12-well culture plate (\~5 × 10^3^ cells per well) for 12 h in a CO~2~ incubator in humidified condition. The cells were incubated with serum-free media for 4 h before the esiRNA transfection. The esiRNA against ITGB8 (n = 3) (EHU014221, Sigma-Aldrich Inc.), targeting sequence is, 5′TCCAGAATGTGGATGGTGTGTTCAAGAG GATTTCATTTCAGGTGGATCAAGAAGTGAACGTTGTGATATTGTTTCCAATTTAA TAAGCAAAGGCTGCTCAGTTGATTAAATACCCATCTGTGCATGTTATAATACCCA CTGAAAATGAAATTAATACCCAGGTGACACCAGGAGAAGTGTCTATCCAGCTGCGTCCAGGAGCCGAAGCTAATTTTATGCTGAAAGTTCATCCTCTGAAGAAATATCCTGT3′ or control siRNA (The Sigma-Aldrich MISSION siRNA; Universal Negative Control, SI001.). There was 1 µl of each esiRNA at a concentration of 50 ng/µl and was mixed with 50 µl of Opti-MEM in RNase-free microcentrifuge tube separately. At the same time, a suspension of 1 µl of lipofectamine with 50 µl of OptiMEM in RNase-free tube was prepared and incubated for 20 min at room temperature. Further, the Opti-MEM-esiRNA suspension and lipofectamine-Opti-MEM-suspension were mixed with each other followed by incubation for another 30 min at room temperature and then added to the wells containing a serum free media (900 µl). Cells were incubated with 5% CO~2~ and 37 °C, in humidified condition, for 12 h. Media was changed after 12 h and grown in complete media for another 12 h. For FAK activity inhibition, when the cell reached 60--70% confluence, the cells were treated with FAK inhibitor at a concentration of 30 nM and another 3 wells were served as a control (n = 3). Cells were grown further for 24 h in an incubator with 5% CO~2~ and 37 °C, in humidified condition. After 24 h incubation, the cells were stained with live cell tracker, Cell Tracker Blue CMF~2~HC Dye prepared in PBS for 30 min and it was replaced with DMEM/F-12, without phenol red. In vitro embryo implantation by JAr spheroids co-culture on endometrial epithelial cell monolayer {#Sec21} --------------------------------------------------------------------------------------------------- The assay was performed according to the previous method^[@CR62]^. The JAr cells spheroids were prepared in DMEM, F-12 medium. Afterwards, the cells were collected after trypsinization in DMEM/F-12 media and the flask was incubated on dancing shaker with 200 rpm, at 37 °C and at 5% CO~2~ concentration in humidified condition for 12 h. Then spheroids were filtered through 100 µm membrane and the filtrate was re-filtered using 70 µm membrane to collect spheroids having size between 70--100 µm in size. These spheroids were incubated for 10 min with live cell tracker dye Cell Tracker Red CMTPX, and re-suspended in DMEM/F-12, without phenol red. The spheroids were co-cultured on ITGB8 siRNA, FAK inhibitor or respective control treated monolayer of Ishikawa cells for 10 min and washed with white media/DMEM/F-12, without phenol red and the attached spheroids were counted and imaged using microscope (CKX41 Trinocular with Cooled CCD Camera Model Q Imaging MP5.0-RTV-CLR-10-C from Olympus, Tokyo, Japan). Intraluminal delivery of MO to silence the endometrial Itgb8 {#Sec22} -------------------------------------------------------------- This is accordance with our earlier published method^[@CR10]^. We received the morpholino oligonucleotides sequence (GGCCGAGCCGCACATAATGCAAAGC, 25 mer) against the mouse Itgb8 target sequence (in bracket); GGTGCGCTCTCAAGTCGGGAGAGCGCATCAGGAAAGCAACTAGGCAG TAGGCACCGGGCGGGCT\[GCTTTGCATT(ATG)TGCGGCTCGGCC\]CTGGCTTTTC (NM_177290.3, Mus musculus integrin beta8 (Itgb8), mRNA) from Gene Tool, Philomath, OR, USA, which does not overlap with other integrins sequence such as Itgb3 or Itgb6 sequences through BLAST. We have already published one study on this given MO-based silencing of iItgb8 ^[@CR10]^. The pregnant female mice underwent a mini-laparotomy under anesthesia at day4 (1000 h) of the window of uterine receptivity to deliver the Itgb8 MO (2 µl of 20 nM) in one of the horn, while the other horn of the same animal (control) received (2 µl of 20 nM) control MO as reported earlier^[@CR10]^. After the Evans blue dye injection, the animals were sacrificed on day5 (1000 h) for the study of embryo implantation sites during post-implantation \[day5 (1000 h)\]. The uterus was photographed to record the number of implanted embryos. Treatment of pregnant mice with FAK inhibitor {#Sec23} --------------------------------------------- The pregnant female mice on the day4 (1000 h) underwent a mini-laparotomy as mentioned in the previous section. One uterine horn of mouse was injected with 2 µl of FAK inhibitor (20 µM) into the lumen through the oviductal site, while another horn was injected with 2 µl of water and served as a control as described elsewhere^[@CR10]^. Implantation sites and inter/non-implantation sites in the uterus were visualized as per earlier mentioned method^[@CR10]^. Delayed implantation mouse model {#Sec24} -------------------------------- We adopted previously described protocol^[@CR57]^ where pregnant female mice were bilaterally ovariectomized on day3 (1600 h) in the presence of anesthetics. Progesterone at 1.0 mg/25 gm of body weight (
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3128, 326, 310, 2, 3824, 21426, 2282, 3198, 789, 13, 285, 253, 673, 310, 2220, 441, 15, 844, 403, 1469, 281, 320, 2509, 789, 4676, 327, 247, 625, 3963, 3720, 13, 285, 436, 3551, 2129, 10316, 253, 806, 273, 1142, 281, 320, 574, 275, 253, 2822, 2852, 15, 7764, 6604, 441, 432, 898, 312, 281, 577, 2617, 281, 1691, 690, 2389, 896, 715, 253, 2282, 15, 1707, 403, 37507, 281, 320, 7932, 13, 23136, 67, 782, 281, 1691, 1066 ]	counts/s) was set to 100% and data obtained after 4 min were used for statistical analysis. Note that βγ-meATP produces a small, but significant, slowing of the decay time. (b) Averaged data from the experiments illustrated in (a) are plotted as concentrations of ATP reached in the bath solution immediately after nerve compression (t = 0 s) and 4 min later (t = 240 s). Compression of spinal roots in the presence of βγ-meATP resulted in higher concentration of ATP and statistically significant slower recovery Discussion {#Sec15} ========== Compression and/or contusion of nerve trunks or spinal roots are common clinical situations with important consequences for nerve function. Previously, changes in electrophysiological parameters of myelinated axons produced by such mechanical stimuli have been studied in detail \[[@CR2]\]. In white matter strips from the ventral spinal cord, it was found that nerve compression produces an immediate, partially reversible decrease of the A fiber compound action potential followed by a persistent conduction block in some of the myelinated axons. These changes in the electrophysiological parameters of A fibers have been also observed in the spinal roots used in the present study (Figures [3](#Fig3){ref-type="fig"} and [7](#Fig7){ref-type="fig"}). The new, additional findings are effects of nerve compression on the concentration of ATP in the extracellular space of an isolated peripheral nerve trunk. Changes in the extracellular concentration of ATP were measured with a time resolution of 1 s. Such online recordings of ATP concentrations were possible because the ATP assay mix was added directly into the organ bath. As described before for epithelia \[[@CR19]\], cultured astrocytes \[[@CR20]\], and postnatal sciatic nerve \[[@CR21]\], the mixture of saline and ATP assay mix was well tolerated by the isolated rat spinal roots used in the present study. The key observation is that nerve compression produces an elevation of the extracellular ATP concentration which returns to the baseline level within a few minutes only. It is very likely that cell lysis contributes to ATP release produced by nerve compression. However, to our knowledge, quantitative aspects and the time course of this type of ATP release are described for the first time. The findings indicate (a) that sufficient ATP is released for activation of axonal P2X receptors and (b) that rapid hydrolysis of ATP may produce enough adenosine for activation of axonal adenosine (A2) receptors. This indicates that chemosensitivity of axons to purines may contribute to the pathophysiology of painful carpal tunnel and other nerve entrapment syndromes. To our knowledge, there is only one previous quantitative report about kinetics of ATP release related to contusion of nervous tissue: Wang et al. \[[@CR24]\] studied the release of ATP following acute impact spinal cord injury. An ATP imaging technique was used to follow ATP release in the setting of this trauma. Imaging was initiated within 10 min after impact, and at this point in time the extracellular concentration of ATP was not elevated in the center of the injury. The authors conclude that ATP released on impact may be hydrolyzed within minutes; our data support this view. A further finding reported by Wang et al. \[[@CR24]\] is a sustained process of pathologically high ATP release in the peritraumatic zone. We do not know whether a similar process takes place in spinal root segments remote from the region of compression because the field of view for the detection of bioluminescence was restricted to the lesion. Our data reveal that compression injury of a peripheral nerve trunk produces high concentrations of extracellular ATP only for an initial transient period. One factor responsible for these fast kinetics may be the in vitro situation which allows rapid diffusion of ATP from the region of nerve compression into the surrounding bathing solution. However, it is also possible that the decline of the ATP concentration is due to extracellular enzymatic degradation and/or consumption by the ATP assay mix. The possible contribution of ATP hydrolysis to the degradation of ATP in isolated spinal roots was studied by means of known inhibitors of ecto-nucleotidases \[[@CR13]\]. One of the compounds used, βγ-meATP, is a potent blocker of ATP hydrolysis by cultured astrocytes \[[@CR20]\]. Also, ARL 67156 is often used as a blocker of ecto-ATPases \[[@CR25]\]. However, application of either compound resulted only in a slight inhibition of ATP hydrolysis by isolated rat spinal roots (see Figure [6](#Fig6){ref-type="fig"}). Also in the isolated rabbit vagus nerve, an incomplete effect of βγ-meATP on ATP hydrolysis has been described \[[@CR15]\]. The reason for these weak effects can be explained in the light of recent findings. It has been described that βγ-meATP preferentially targets the eNPP family of ecto-ATPases (eNPP1 and/or 3) over the CD39 family of eNTPDases \[[@CR22]\]. However, the opposite situation, i.e., a prominent role of eNTPDases for hydrolysis of ATP, seems to be important for peripheral nerve preparations. In particular, the presence of eNTPDase2 was detected on nonmyelinating Schwann cells \[[@CR16]\]. ARL 67156, too, only slightly inhibited ATP hydrolysis by isolated rat spinal roots. This observation is in accordance with the notion that this reagent acts as a modestly efficacious inhibitor of both eNPP and eNTPDase-type nucleotidases \[[@CR22]\]. In a recent study, ARL 67156 revealed the highest inhibitory potency for NTPDase1. It was considerably less effective on NTPDase3 and essentially ineffective on NTPDase2 \[[@CR26]\]. The possible contribution of ecto-nucleotidases for the kinetics of ATP concentration following nerve compression was tested by means of βγ-meATP because this compound was more potent as a blocker of ecto-nucleotidases in spinal roots as compared to ARL 67156. It was observed that βγ-meATP (a) enhanced the compression-induced release of ATP into the bath solution and (b) induced a slowing of the decline in the extracellular ATP concentration in the period following the compression (see Figure [8](#Fig8){ref-type="fig"}). Taken together, these observations indicate that an increase in the extracellular concentration of ATP in the trunk of a peripheral nerve is limited by activity of ecto-nucleotidases. However, at present, a more quantitative analysis is not possible due to the lack of potent inhibitors of such enzymes in peripheral nerve. It is possible that ATP release produced by compression of a peripheral nerve trunk contributes to "positive" symptoms such as the development of pain. However, the concentrations of ATP reached in the extracellular space after nerve injury were only in the nanomolar range (see Figure [4](#Fig4){ref-type="fig"}). Such concentrations of ATP do not activate purinergic receptors in the membrane of nociceptive neurons. However, bioluminescence measured in the present study is mainly induced by ATP in the solution surrounding the nerve trunk. It is very likely that much higher concentrations of ATP are reached in the small extracellular space in the vicinity of nociceptive axons. It has been estimated that only 1% or less of the intracellular ATP pool needs to be released to activate maximally any and all purinoceptors \[[@CR27]\]. In fact, cytosolic ATP released by cell damage produces transient currents in cultured sensory (nociceptive) neurons via activation of ionotropic P2X receptors \[[@CR28]\]. This is an example for a fast functional response due to a transient elevation of extracellular ATP concentration. However, there are several possibilities of how short lasting extracellular ATP transients may induce long lasting alterations in axonal excitability and/or glial activity: (a) degradation of ATP to adenosine could result in an increase of axonal excitability in unmyelinated peripheral nerve fibers via metabotropic A2 receptors \[[@CR7], [@CR18]\]. Production of adenosine from ATP has been shown for isolated vagus nerves \[[@CR15]\] and pain-enhancing actions of adenosine via P1 (A2) receptors have been described \[[@CR5], [@CR17]\]. (b) Long lasting activity in peripheral nociceptive neurons has been discussed as the result of cytokine release induced by activation of purinergic P2X~7~ receptors \[[@CR29], [@CR30]\]. (c) Activation of P2Y receptors on Schwann cells \[[@CR9]--[@CR12]\] may have long lasting consequences similar to the development of P2Y-related gliosis observed in astrocytes \[[@CR31], [@CR32]\]. We would like to thank Ms. Christina Müller for valuable technical assistance and Dr. Uta Rundshagen for help in some of the experiments. This study was supported by the Deutsche Forschungsgemeinschaft (SFB 391/A1). ARL 67156 : 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5-triphosphate βγ-meATP : Adenylylmethylenediphosphonate disodium salt CAP : Compound action potential eNPP : Ecto-nucleotide pyrophosphatase/phosphodiesterase eNTPDase : Ecto-nucleoside triphosphate diphosphohydrolase HEPES : N-(2-Hydroxyethyl)piperazine-N\\prime-(2-ethanesulfonic acid) Work party that is! Our beloved course needs work, and the time is upon us. We are going to be doing work parties on a more regular basis, and this coming week brings the first of many to be had in the near future. Please join us from 9am to 4pm to put some love back into the course. There are nets to be replaced, tanbark to put down
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JOHNSON v. James R. WILSON. No. 43867. Supreme Court of Louisiana. February 15, 1960. Rehearing Denied March 21, 1960. 451 Seale, Hayes, Smith & Keogh, Baton Rouge, for applicant. Joseph A. Gladney and J. H. Percy, Jr., Baton Rouge, for respondent. McCALEB, Justice. This suit for damages arises out of an automobile accident occurring at approximately 1:00 p. m. on November 28, 1955, about eight miles north of Baton Rouge on Plank Road, a two-lane two-way hard surfaced highway, when an automobile owned and driven by plaintiff struck a pickup truck owned and operated by defendant. At the time of the accident, plaintiff was attempting to overtake and pass the truck which defendant had edged over the center line of the roadway preparatory to making a left turn onto the premises of his servant. Plaintiff instituted the action to recover damages to his car, amounting to $608.30, charging that the accident was attributable solely to the negligence of defendant. This was denied by defendant in his answer and he, having sustained personal injuries in the accident, reconvened for $235,965.37. He alleged that plaintiff was grossly negligent and, alternatively, pleaded contributory negligence and the doctrine of last clear chance. The case was tried on these issues before a jury and resulted in a verdict for defendant in the sum of $8,507.37. Judgment was rendered in accordance with this verdict and plaintiff appealed therefrom to the Court of Appeal, First Circuit, where the judgment was affirmed. See Johnson v. Wilson, 97 So.2d 674. At plaintiff's instance we granted a writ of certiorari[1] and the case has been argued and submitted for our decision. There is no important disagreement between the parties as to the facts of the case as found by the Court of Appeal. Nor does counsel for plaintiff take serious issue with that court's ruling that plaintiff was guilty of negligence in striking the Wilson car in that he was travelling at a speed in excess of 60 miles per hour (in violation of Section 223 of the Motor Vehicle and Traffic Regulation Statute, R.S. 32:223) and was somewhat inattentive in his driving when he attempted to overtake and pass defendant's truck. On the other hand, counsel proclaimed that the Court of Appeal erroneously exonerated defendant from blame in view of the uncontroverted facts which disclose that defendant violated positive provisions of law, R.S. 32:235(B), in crossing over the center line of the highway in order to negotiate a left turn and that he was also imprudent in pulling into the left lane without looking into his rear view mirror immediately before undertaking such a movement. We think that this complaint is well founded in law. The facts of the case are substantially as follows: At the place of the accident the highway runs relatively straight and flat in both directions. 452 Defendant testified that he was about 500 feet from where he was to turn left into his servant's driveway when he first noticed, in his rear view mirror, the Johnson car which was at that time between one-fourth and one-half a mile behind him; that he was travelling at a speed of 35 miles per hour, so he slowed down, rolled down his window glass and stuck his arm straight out as a signal of his intention to make a left turn; that, when he was 80 to 100 feet from the driveway, he looked in his mirror again and saw the Johnson car 300 to 400 feet behind him; that he never looked back for the overtaking car again and that, when he was 70 feet from the driveway, having meanwhile slowed his speed to 20 miles per hour, he edged over the center line of the highway and began a gradual left turn, believing that the Johnson car would pass him on his right. When defendant's truck reached a point 35 feet from his servant's driveway, the left front wheel was approximately four feet left of the highway center line and the left rear wheel about two feet left of the center line. It was at this point that the right front fender of the Johnson car collided with the left rear fender and wheel of defendant's truck, displacing the wheel and causing the truck to overturn. We think the foregoing facts plainly exhibit that defendant was guilty of negligence which substantially contributed to the accident and but for which the accident would not have happened. However, we intermit our discourse on this subject to dispose of the contention made here, and in the lower courts, by defendant's counsel that plaintiff may not urge contributory negligence because he did not specially plead that defense by way of answer to the reconventional demand. Counsel say that Article 377 of the Code of Practice requires that a plaintiff file written answer to a reconventional demand and that the Court of Appeal, Second Circuit, in Young v. Geter, 174 So. 661 has indicated that whenever a plaintiff relies upon a special defense to defeat a reconventional demand, such defense must be formally pleaded. Counsel's position is not tenable. Article 329 of the Code of Practice declares that when the defendant alleges new facts in his answer "* * * these shall be considered as denied by the plaintiff; therefore neither replication nor rejoinder shall be admitted." Conformably with this article, the Court has held on numerous occasions that, since neither replication nor rejoinder are admitted under our pleadings, the allegations of an answer are open to any objections of law and fact without special plea and that, if the defendant is taken by surprise, the proper remedy is a continuation or a new trial. Patton's Heirs v. Moseley, 186 La. 1088, 173 So. 772; Roy O. Martin Lumber Co. v. Hodge-Hunt Lumber Co., 190 La. 84, 181 So. 865; Lee v. Perkins, 195 La. 939, 197 So. 607; Galiano v. Galiano, 213 La. 332, 34 So.2d 881; Cheramie v. Stiles, 215 La. 682, 41 So.2d 502 and Loew's Inc. v. Don George, 227 La. 127, 70 So.2d 534. Article 377 of the Code of Practice, relied on by defense counsel, provides that reconvention may be pleaded by a defendant either as an exception in his answer to the principal demand or he may institute a distinct and separate demand before the court in which the main demand is pending "* * * and the original plaintiff shall be bound to answer without pleading to the jurisdiction of the court, even, if he has his domicil elsewhere, * * ". The quoted provision that the original plaintiff shall be bound to answer without pleading to the jurisdiction does not mean, as counsel contend, that a written answer shall be filed to the reconventional demand. Hobson v. Woolfolk, 23 La.Ann. 384; Lamorere v. Avery, 32 La.Ann. 1008 and Burge v. Batson, 149 La. 542, 89 So. 687. It simply signifies that the original plaintiff may not question the jurisdiction of the court " * * even if he has his domicil elsewhere 453 * *" since he has submitted himself to the court's jurisdiction by filing the original demand. The article must be read in connection with Article 329 of the Code of Practice which prohibits replications and rejoinders and, when thus considered, it cannot be construed (as contended by counsel) to require a formal answer or special plea to a reconventional demand. The statement in Young v. Geter, supra, indicating a contrary view, was wholly unnecessary to the decision of the case and, hence, is to be regarded as pure dictum. Returning, now, to the issue of defendant's contributory negligence, we are convinced that he was imprudent in two particulars which had causal connection with the accident. First, it is shown by defendant's own testimony that, after he had seen the Johnson car 300 to 400 feet behind him and was undoubtedly aware that this car was engaged in an overtaking operation, he edged his truck over the center line and into the left (or passing) lane without looking back again in order to ascertain whether it was hazardous for him to do so.[2] It is seen from the statement of defendant, which we have quoted below in Footnote No. 2, that he felt that, when he had given a hand signal indicating his intention to make a left turn, he was entitled to engage in that maneuver irrespective of the speed of plaintiff's car or the distance of the car from the truck at that time. But, of course, defendant did not have the legal right to commence a left turn by driving over the center line when confronted with an unfavorable traffic condition and, had he checked to his rear, just before turning, he would have realized that the Johnson car was rapidly closing the 300 to 400 foot gap between the car and the truck, which he had previously observed, and prudence would have demanded that he wait until the speeding car either slowed or passed before beginning his angling turn. See Cassar v. Mansfield Lumber Co., 215 La. 533, 41 So.2d 209 and Leonard v. Holmes & Barnes, 232 La. 229, 94 So.2d 241, 242, wherein we approved a ruling of the Court of Appeal that the driver of defendant's truck was negligent "in that he failed to look to his rear just before attempting the lefthand turn, under the well settled law of this state that a person who attempts to make a lefthand turn on a public highway must be sure before doing so that the turn can be made in safety".
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835, 703, 6940, 432, 22824, 1253, 25929, 15, 50276, 36945, 11612, 253, 2499, 273, 5002, 13, 24538, 313, 25929, 1253, 25197, 582, 835, 703, 369, 247, 5974, 273, 6911, 34450 ]	s on her back. I pin her arms to the ground. She stops, glaring up at me. Tears swim in her eyes, reflecting the moonlight. She blinks hard, as if to push back the tears. Our ragged breathing fills the quiet night. “Are you ready to listen to me?” She swallows, and nods. I wait until I feel her body relax beneath mine, then ease my hands off her arms, and unpin her legs from my thighs. Her knee jerks up, toward my groin, and I tilt my hips fast. Christ, she tastes like fire and tears and fear. Her mouth is the most fantastic thing I’ve ever tasted. Her bunched muscles relax beneath my fingers as a whimper rushes through her mouth. Pulling back, I nip her jaw, tracing a path to her ear and running my tongue over its outline. “You taste so damn good, Sophie. Want to kick me again?” She doesn’t answer. I pull back, quirking a brow at her. Fuck, she’s so beautiful with her flushed cheeks and plump, sweet lips. She shakes her head. “Good.” I brush that little dimple on her chin with my fingertips. “Trust. Me.” She bites the corner of her bottom lip and nods. “This talk had better be good, or I might stab you while you sleep.” Book & Author Details: A Need So Insatiable by Cecilia Robert (Hearts #1) Publication date: March 8th 2014 Genres: New Adult, Romance Synopsis: “You’ve owned me from the moment I walked into that music room. You’ve wrapped yourself in my heart and mind. I can’t get you out. I don’t want to.” ~ Rafael Van Rees Sophie Fisher’s life is on fire. If she’s not ducking around corners or slipping out of windows to escape the debt collectors her father’s death has left knocking on her door, she’s dealing with her rebellious, fifteen-year-old sister, Lilli. And, as if that’s not enough, Rafael Van Rees crashes into her life—literally—bringing with him a past the public has no idea of. Can she unravel his mysteries before he unravels her, or will his presence finally force her to face the demons she’s trying to outrun? Rafael Van Rees prides himself on being in control of his destiny, music and women. As far as he is concerned, his past is a black cloud in the distance–until he meets Sophie, that is, and his world spins out of control in more ways than one. He knows the darkest sins and secrets eventually reveal themselves, but when it comes to Sophie, he’ll stop at nothing to protect her from his past. Even if it kills him. I write YA, NA and Adult. My motto: Passion rules. I enjoy writing stories about people finding love in the most unexpected places, coupled with adventurous journeys, whether it's urban, fantasy, sci-fi, contemporary or paranormal romance. There's always a happy ever after, no matter how long it takes to get there. TRADE-IN and get $$$$ New FIRE HD 10 Readsy's Best Book Blog 2017 Sign up for Debra's Newsletter Want to be the first to know about new releases, contests and special deals? Sign up here. * indicates required Email Address * First Name Last Name Email Format html text mobile Search This Blog NetGalley Top Reviewer Review Status CLOSED FOR SUBMISSIONS: I have an overwhelming TBR pile at the moment and am NOT accepting any new books for review. The books reviewed on this site are either digital copies or ARCs sent by publishers or authors. I never accept payment in exchange for a review. Total Pageviews GUEST POSTS ARE WELCOME! If you are interested in contributing a guest post for Two Ends of the Pen, please send me an email at:dlmartin6 AT yahoo DOT com. Your article/post needs to have some relevance to writing, books, ebooks, epublishing, tips for blogging, marketing strategies, etc. You get the idea--really, anything to do with books and being an author in general. I've also highlighted a number of guest posts in the sidebar to help you understand what I'm looking for in a post. I look forward to sharing your posts with my readership. Requesting an Author Interview If you would like to request an author interview, please send an email to dlmartin6 AT yahoo.com and let me know if you are strictly an indie author or an indie/traditionally published author. This way I can send you interview questions to suit your book(s). All the questions are just suggestions, you may add/change/delete any of them. Put "Requesting Author Interview" in the email subject line. Interviews are posted on a first-come first-serve basis and will be posted ASAP depending on the backlog of other posts for the blog. In addition to your interview spotlight page, you will also be added to the list of Author Interviews page. Please do NOT ask me to review your book in your author interview request. I am CLOSED to review submissions. Contact Me If you would like to contact Deb directly, please send a message to:dlmartin6 [at] yahoo [dot] com.News Release Tuesday, April 25, 2017 Attempt Murder Suspect Sought NR17113sr Los Angeles: Detectives from the Los Angeles Police Department's Rampart Area are asking for the public's assistance in identifying attempt murder suspects. On Thursday, December 29, 2016, between 1:50 a.m., and 2:00 a.m., the victims and suspects met inside the Gold Room Bar at 1558 W. Sunset Blvd. The victims and the suspect are observed having drinks together and are captured on the business' security cameras. When the bar closed, the victims and the suspect all left at the same time. The victims and suspect engaged in a verbal dispute. The suspect struck Victim-2 on the side of the head, causing a laceration. Victim-1 tried to keep the peace after the physical altercation and went to talk to the suspect. The suspect then struck Victim-1 with the knife, cutting him on his neck and face. The suspect fled in a dark colored 4 door sedan. The suspect is described as male Hispanic, brown hair, brown eyes, 5 feet 8 inches to 5 feet 10 inches tall, weighing between 200 to 210 pounds, and is 25 to 30 years old. The suspect has a beard and multiple tattoos on his face, neck and head. He was last seen wearing a black jacket with gray pants. Anyone with information about this case is asked to contact Officer Morales, Rampart Gang Detectives, at (213) 484-3660 or (213) 484-3655. During non-business hours or on weekends, calls should be directed to 1-877-LAPD-24-7 (1-877-527-3247). Anyone wishing to remain anonymous should call the L.A. Regional Crime Stoppers at 1-800-222-TIPS (800-222-8477) or go directly to www.lacrimestoppers.org. Tipsters may also visit www.lapdonline.org, and click on "Anonymous Web Tips" under the "Get Involved-Crime Stoppers" menu to submit an online tip. Lastly, tipsters may also download the "P3 Tips" mobile application and select the L.A. Regional Crime Stoppers as their local program.159 F.3d 1357 U.S.v.Kirk* NO. 98-40020 United States Court of Appeals,Fifth Circuit. September 23, 1998 Appeal From: E.D.Tex., No.197CR381 1 Affirmed. * Fed.R.App.P. 34(a); 5th Cir.R. 34-2 Maurya Simon Maurya Simon (born December 7, 1950) is an American poet, essayist, and visual artist. She is the author of ten collections of poetry, including two books that have been nominated for a Pulitzer Prize and a National Book Award. Her most recent volume of poetry is The Wilderness: New and Selected Poems (Red Hen Press, 2018). Early life and education Born in New York City, Simon is the daughter of the Los Angeles visual artist, Baila Goldenthal, and the ethnomusicologist and composer, Robert Leopold Simon. She spent her early years living in Europe with her family, and later moved to Hermosa Beach in southern California, where she lived from 1959–1968. Simon attended the University of California, Berkeley (1968–1971), where she was a student of Robert Gren
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4602, 342, 436, 4422, 281, 18230, 3988, 390, 21526, 468, 342, 985, 5300, 285, 16, 263, 8553, 15, 380, 897, 390, 3268, 273, 5657, 4158, 323, 48637 ]	the website is offered to you conditioned on your acceptance without modification of all terms, conditions, and notices contained or referenced herein (the “Terms of Use”). 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512, 253, 1551, 273, 187, 2577, 673, 3909, 15, 2752, 12247, 4307, 323, 21314, 594, 359, 574, 12823, 1475, 13, 533, 672, 309, 187, 14541, 562, 326, 12823, 812, 795, 26209, 64, 281, 1016, 643, 13, 309, 6497 ]	uni-color-subtitle: #555555; // 二级标题颜色 $uni-font-size-subtitle: 36upx; $uni-color-paragraph: #3f536e; // 文章段落颜色 $uni-font-size-paragraph: 30upx; High density lipoprotein cholesterol, total cholesterol and triglycerides in serum after a single exposure to prolonged heavy exercise. Serum high density lipoprotein (HDL) cholesterol, total serum cholesterol and triglycerides were determined in twenty men before, immediately after, and 1, 2 and 4 days after a 70 km cross-country ski race. HDL cholesterol increased by 12% of the pre-race level immediately after the race, rose further to 17% above the initial level on the following day, and was still elevated 4 days after the race. LDL + VLDL cholesterol, however, showed a tendency to decrease immediately after the race and was reduced by 17% and 11% of the pre-race level on the following 2 days. Triglycerides were reduced by 30% of the initial level immediately after the race, were still low on the following day, but were restored to normal 2 days after the race. It is concluded that a single exposure to prolonged heavy exercise induces changes in the HDL metabolism, showing that the physical exercise per se plays an important role for the increased HDL level seen in well-trained athletes.Allow users to remove their own instant invites If a user creates an instant invite to a server, they should be able to remove them with a "remove invite" button or in the dropdown when you would go to notification settings, privacy settings, leave server etc. Reasons why is so if they do not want their invite to exist anymore and don't have access to the server's settings, they can still remove their own invites. (I hope I make sense haha)The Tobacconist (German) UK Jewish Film Festival More information about Release date: 10 November 2019 Running time: 90 minutes Plus short On the Beaches. Bruno Ganz is superb as Sigmund Freud in this heart-rending adaptation of Robert Seethaler's novel. 17-year-old Franz takes up a job at a Viennese tobacconist shop, where he meets the renowned professor. Fascinated by his theories, Franz seeks Freud's advice after falling in love with a dancer. His confusion about love and sex echoes the political turmoil caused by Hitler's imminent annexation of Austria, and Freud's own indecision about leaving the country. This drama sensitively explores its protagonists' longing – for the love of a woman, and for a homeland. Sponsored by: David MondSearch The Independent Inquiry into Child Sexual Abuse Investigating the extent to which institutions have failed to protect children from sexual abuse The Independent Inquiry into Child Sexual Abuse will investigate whether public bodies and other non-state institutions have taken seriously their duty of care to protect children from sexual abuse in England and Wales. Read our Opening Statement and the November update statement. We will identify institutional failings where they are found to exist. We will demand accountability for past institutional failings. We will support victims and survivors to share their experience of sexual abuse. And we will make practical recommendations to ensure that children are given the care and protection they need. The Inquiry is independent of government. The Chair is Professor Alexis Jay OBE, who is supported by a Panel, a Victims and Survivors Consultative Panel, and other expert advisers. More about who we are. Share your experience We are working with victims and survivors who want to assist the Inquiry in its work. You can share your experience of sexual abuse with us. Many victims and survivors have already taken part in the Truth Project and some have asked us to share their feedback on the process. To gain an understanding of the most up to date research on perpetrators of online-facilitated child sexual abuse, we have commissioned NatCen Social Research to undertake a review of published and unpublished literatureWireless communications systems are widely deployed to provide various types of communication content such as voice, video, packet data, messaging, broadcast, and so on. These systems may be multiple-access systems capable of supporting communication with multiple users by sharing the available system resources (e.g., time, frequency, and power). Examples of such multiple-access systems include code-division multiple access (CDMA) systems, time-division multiple access (TDMA) systems, frequency-division multiple access (FDMA) systems, 3GPP Long Term Evolution (LTE) systems, and orthogonal frequency-division multiple access (OFDMA) systems. Generally, a wireless multiple-access communications system may include a number of base stations, each simultaneously supporting communication for multiple mobile terminals. Base stations may communicate with mobile terminals on downstream and upstream links. In some cases, wireless communications systems may not utilize portions of the spectrum because the portions are not big enough to fit a standard waveform. New techniques may be developed to utilize these smaller portions of the spectrum. However, if current systems are scaled, there may be additional issues (e.g., time stretching) that arise.Q: How can I create an Animated Button with a Sprite Sheet using Javascript? I am trying to create an animated button using a sprite sheet. The animation should play on hover and then on mouseout the animation should finish and then stop. How can I go about doing this? I have tried setting the background of a div and controlling the background position through hover events. I can get the background position to set itself properly but each change goes so fast it might as well be instant and so the animation does not show itself. Any suggestions would be helpful. After a lot of searching with no luck I am not sure what else to try. Thank You! A: the best advice would be to use a CSS3. pretty easy no need for javascript: take a look at this for example: http://codeitdown.com/css-sprite-animations/ example here: http://jsfiddle.net/drukaman/ued7mLha/1/ An Unschooling Manifesto - jlhamilton http://blogs.salon.com/0002007/2009/04/25.html#a2369 ====== 3pt14159 I was home schooled for grade 2 and 3 and private schooled the rest. Throughout that whole period my best years of learning were grades 11 and 12. The reason for this was that during all other private school years I was forced to sit and trod through material that was far too easy. I never did the homework because I could still pull of 70s and didn't see the value in having a higher grade. I was invited to province wide math contests, but was only scoring 72% in math. Finally my math teacher in grade 11 asked me how this could be. (He also happened to be the vice principal) I told him clearly: I hate class and I hate homework. They are not challenging, so I refuse to put effort into them. He suggested the exact same thing that article advocated. The change was immediate. By grade 12 I was scoring 97 in calculus, 95 in linear algebra and 92 in finite math. All because I could move at my own pace. When I had exhausted the course material my teacher gave me books like Aristotle's mathematical proofs. These changed my life. Imagine if this type of freedom had been available my whole life. My parents tried when I was young (via homeschooling) but my social development suffered too much and I wasn't getting the passion for the subjects that teachers can impart. If I were to raise children now I would insist on a school that used the <http://en.wikipedia.org/wiki/Montessori> style. It might not be the best for everyone, but for even slightly gifted children I think it will drastically improve their mental growth. ~~~ stanleydrew I think Montessori is unbelievable. I went to a Montessori school through third grade and loved it. But I don't think it works for everyone. My brother didn't enjoy it or do as well in the unstructured environment as I did. So I think multiple kinds of education are necessary. The problem is that there's a lack of information about education options for most people. And perhaps an issue of affordability. You might say that the public school system ought to offer alternatives to the structured model. And maybe it should. I don't know how much that would cost. But I'm sure a lot of people would take advantage of it. ~~~ jacoblyles One of the great things about the market model is decentralized choice. Nobody has to decide what choices are offered for everybody. That decision is between the consumers and the producers. And private school voucher programs that currently exist cost as little as 25% of the cost of educating that same child in public school. ------ jgilliam My parents tried to home school me in the late 80's, early 90's (they were very religious). It turned into unschooling, because I was able to plow through the "curriculum" in very little time, and then spent all the rest of my time online. My dad worked for IBM so we had computers around, but when I found out that computers could _talk_ to each other, I fell
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5654, 15, 8256, 273, 253, 6158, 3133, 281, 452, 644, 29101, 285, 20296, 1503, 22369, 262, 285, 3697, 8824, 5282, 15, 9613, 399, 14, 15490, 581, 273, 253, 25157, 71, 378, 16, 36, 33690, 686, 1328, 13535, 8, 369, 36704, 275, 659, 8698, 372, 46568, 79, 333, 13, 6420, 14, 26139, 273, 659, 25298, 14, 9960, 14, 37, 1644, 13, 835, 697, 10402, 497, 26174, 12701, 323, 6039, 2037, 85, 12173, 15, 733, 310, 417, 2590, 604, 436, 369, 271, 14047, 897, 273, 3565, 4668, 6500, 390, 3365, 247, 4653, 5763, 15, 187, 187, 2374, 2164, 2552, 21930, 1529, 25963, 9251, 8260, 8019, 84, 497, 711, 4066, 2147, 281, 3127, 296, 9251, 8260, 13, 533, 352, 310, 11543, 326, 597, 574, 7244, 407, 2393, 3978, 15, 6408, 253, 6680, 323, 13531, 13183, 1529, 10488, 497, 2197, 281, 253, 9025, 1690, 1264, 3923, 20470, 15, 380, 2457, 3578, 5654, 20470, 3164, 858, 417, 12666, 275, 673, 281, 1379, 629, 275, 253, 8615, 15, 187, 187, 12309, 8260, 2070, 6285, 9333, 13, 8523, 6146, 14, 8535, 273, 20159, 13, 574, 32700, 14, 27248, 9251, 8260, 8019, 84, 15, 733, 369, 2197, 1529, 19525, 353, 76, 8019, 84, 347, 47105, 327, 854, 4163, 21930, 15, 11977, 5536, 8615, 342, 253, 7108, 13, 407, 3307, 4223, 253, 9025, 574, 816, 3578, 1669, 15, 2091, 253, 12472, 394, 9251, 8260, 9333, 17054, 73, 1504, 13, 6146, 273, 7785, 13, 369, 7730, 281, 253, 6680, 323, 13531, 13183, 275, 3563, 4163, 352, 574, 11614, 9251, 8260, 8019, 84, 15, 7850, 643, 4430, 9698, 8615, 9411, 2486, 1264, 5662, 9251, 8260, 8019, 84, 342, 253, 2159, 6879, 2188, 5654, 15, 11977, 253, 5685, 19015, 285, 253, 8615, 387, 659, 40233, 253, 9025, 369, 760, 2104, 281, 19553, 1740, 9251, 8260, 8019, 84, 432, 253, 34268, 15, 187, 187, 510, 411, 2843, 257, 14, 3528, 3199, 8260, 22387, 7730, 281, 13531, 13183, 497, 671, 13496, 342, 253, 9251, 8260, 8019, 15, 380, 337, 296, 13575, 9251, 8260, 9333, 43661, 1676, 26228, 2006, 6352, 18816, 13, 9268, 273, 30167, 13, 1364, 2122, 14327, 14, 9389, 9251, 8260, 8019, 84, 275, 697, 337, 296, 40202, 35843, 15, 329, 2007, 4314, 497, 275, 323, 8706, 15, 6304, 2373, 447, 1309, 3978, 37752, 281, 1529, 13719, 14, 13524, 20470, 15, 2732, 1146, 2197, 281, 13531, 13183, 407, 3563, 4163, 253, 9025, 369, 2104, 281, 1673, 21116, 14, 531, 9251, 8260, 8019, 84, 15, 187, 187, 510, 374, 2109, 13575, 9251, 8260, 9333, 23184, 30674, 407, 253, 5068, 273, 3978, 574, 13719, 14, 12496, 9251, 8260, 8019, 84, 13, 273, 534, 3578, 497, 275, 253, 22586, 15, 3840, 40547, 273, 44878, 5486, 326, 253, 374, 2109, 13575, 369, 281, 1673, 247, 2264, 273, 32571, 14, 13524, 9251, 8260, 8019, 84, 13, 534, 2908, 253, 21629, 25157, 71, 500, 15, 6676, 273, 841, 497, 3663, 275, 253, 15657, 336, 90, 11320, 387, 253, 990, 273, 4163, 13, 2167, 690, 273, 253, 353, 76, 8019, 84, 432, 374, 2109, 13575, 7303, 281, 8773, 15, 187, 187, 510, 898, 394, 13575, 9251, 8260, 9333, 11826, 864, 296, 21393, 257, 574, 14327, 14, 19521, 9251, 8260, 8019, 84, 387, 253, 1265, 273, 253, 4544, 13, 533, 5093, 273, 841, 497, 275, 253, 8979, 15, 7850, 7586, 9025, 884, 394, 13575, 1879, 41748, 4978, 369, 2104, 281, 8745, 10488, 14, 27248, 285, 407, 4260, 14, 20266, 574, 760, 3663, 13265, 15, 1723, 13, 816, 4314, 9251, 8260, 8019, 84, 497, 2130, 281, 2186, 253, 7108, 387, 17699, 15, 380, 36418, 1249, 394, 13575, 18816, 18936, 423, 574, 271, 14047, 4757, 273, 8437, 9251, 8260, 8019, 84, 2167, 760, 32700, 14, 531, 497, 11757, 4704, 15, 2896, 884, 4223, 846, 1199, 5536, 8615, 253, 9025, 574, 816, 15342, 1669, 15, 187, 187, 3463, 21930, 253, 3199, 8260, 22387, 497, 8127, 22128, 327, 892, 518, 11942, 10877, 327, 2716, 14, 46488, 323, 2329, 17147, 13, 1690, 253, 322, 69, 44, 71, 91, 884, 16, 21, 285, 322, 69, 44, 71, 91, 818, 16, 18, 15, 496, 13531, 13183, 253, 2884, 518, 4029, 8260, 6480, 9, 85, 10, 970, 21647, 14, 20989, 39271, 369, 275, 2579, 3185, 273, 253, 2884, 518, 4029, 8260, 8019, 342, 253, 374, 2109, 13, 898, 394, 13, 9251, 8260, 2070, 6285, 285, 337, 296, 13575, 9251, 8260, 6852, 3836, 15, 496, 3762, 4314, 2884, 518, 4029, 8260, 8019, 353, 2381, 8382, 40990, 497, 18564, 281, 253, 3270, 14, 1094, 12517, 2593, 273, 247, 3199, 8260, 810, 3825, 17929, 8, 2567, 15, 496, 4163, 21930, 313, 251, 2929, 387, 1878, 10, 353, 2381, 8382, 88, 356, 561, 497, 7922, 281, 253, 1249, 394, 13575, 285, 12472, 394, 9251, 8260, 6852, 3836, 15, 15997, 3710, 3904, 273, 41436, 8382, 16668, 671, 3047, 11757, 275, 13531, 13183, 15, 187, 187, 510, 3480, 273, 32468, 22387, 13, 534, 497, 2918, 6146, 273, 253, 1023, 460, 13, 5486, 253, 3199, 91, 398, 17564, 253, 1308, 2084, 273, 253, 8615, 15, 2896, 253, 5068, 273, 4163, 21930, 253, 440, 1661, 42424, 15942, 11847, 273, 253, 3199, 91, 398, 574, 2668, 697, 17935, 27, 5976, 591, 1399, 273, 253, 9251, 8260, 8019, 84, 285, 9135, 591, 1399, 273, 253, 42422, 497, 275, 253, 9363, 1305, 1502, 15, 13036, 281, 27438, 434, 7088, 5308, 13413, 327, 1283, 4163, 9251, 8260, 8019, 84, 273, 3127, 296, 9251, 8260, 2112, 342, 31822, 20470, 432, 32592, 9251, 8260, 35843, 36629, 497, 7270, 275, 253, 32683, 22185, 25485, 2822, 775, 47532, 1952, 372, 3083, 570, 6169, 884, 10294, 9268, 273, 6047, 257, 15, 380, 2538, 497, 25205, 13, 342, 20470, 3365, 27352, 28636, 14, 3487, 751, 597, 497, 23908, 15, 4325, 247, 3490, 273, 670, 13719, 3199, 91, 398, 689, 2716, 497, 3663, 13, 1142, 2571, 9958, 8651, 20101, 15, 187, 187, 8430, 7088, 5308, 4242, 281, 29709, 253, 16088, 10458, 5685, 809, 2979, 352, 9945, 2007, 281, 253, 863, 9174, 273, 253, 9251, 8260, 8019, 84, 275, 13531, 13183, 285, 6518, 9176, 731, 275, 253, 4782, 8776, 15, 496, 4223, 323, 253, 23347, 4828, 14, 35946, 387, 16905, 404, 1411, 253, 7108, 253, 20003, 812, 760, 9580, 28089, 14, 23587, 9251, 8260, 4744, 8019, 84, 285, 14327, 14, 23587, 42422, 13, 11467, 253, 1072, 18766, 1180, 326, 574, 644, 10098, 275, 253, 3302, 2983, 13, 534, 3206, 13719, 14, 23587, 9251, 8260, 8019, 84, 285, 28089, 42422, 15, 187, 187, 34, 1643, 3618, 1996, 13, 7591, 281, 3831, 253, 2448, 2740, 483, 13, 253, 5685, 8663, 369, 275, 1481, 5056, 8630, 285, 840, 18195, 387, 401, 7080, 885, 285, 16473, 15, 2732, 253, 15764, 323, 13531, 13183, 5747, 253, 3361, 273, 21548, 3199, 91, 398, 15823, 281, 253, 13575, 387, 21155, 3296, 13, 27438, 369, 417, 1691, 745, 25251, 24636, 15111, 18733, 326, 7369, 275, 253, 37359, 6680, 323, 253, 11537, 460, 14270, 15, 187, 187, 17588, 253, 9251, 8260, 88, 23510, 434, 6429, 16292, 275, 13531, 13183, 407, 3563, 21930, 253, 9251, 8260, 8019, 369, 275, 1077, 2159, 6186, 15, 1284, 247, 906, 273, 45120, 34268, 863, 9174, 285, 253, 20638, 4269, 407, 32683, 25485, 253, 3199, 8260, 22387, 19460, 281, 1673, 1097, 247, 40716, 273, 9251, 8260, 8019, 84, 285, 247, 40716, 273, 42422, 15, 380, 374, 2109, 285, 1903, 394, 9251, 8260, 285, 253, 374, 2109, 13575, 285, 898, 394, 13575, 9251, 8260, 6852, 3836, 1016, 574, 767, 4413, 273, 659, 86, 40, 9222, 11942, 3185, 273, 9251, 8260, 8019, 84, 28, 253, 898, 394, 285, 12472, 394, 9251, 8260, 6852, 3836, 574, 642, 9251, 8260, 8019, 387, 512, 13, 1673, 272, 3185, 1264, 4413, 273, 659, 86, 15121, 15, 5131, 22387, 574, 247, 2014, 40716, 273, 6804, 9251, 8260, 8019, 84, 285, 42422, 15, 380, 1273, 40716, 574, 281, 320, 18528, 407, 3199, 8260, 46550, 1063, 285, 331, 321, 78, 2510, 348, 3090, 21239, 5085, 15, 187, 187, 1992, 1056, 598, 323, 824, 2159, 27366, 13, 2720, 281, 18816, 434, 8986, 1780, 69, 41564, 13413, 253, 337, 296, 13575, 369, 19079, 407, 247, 40716, 273, 5536, 31822, 309, 2513, 13, 1223, 253, 643, 22387, 574, 281 ]	production until the end of the war, although the Jagdpanzer IV and Panzer IV/70 took priority. The Hornisse made its first appearance at Kursk. Its powerful and long-ranged 88mm gun meant it could kill Soviet tanks at great distances – this helped cancel out the risks caused by its high profile and light armour. These Hornisse belong to the 519th Heavy Panzerjäger Battalion serving on the Eastern Front in the winter of 1944. This was one of six such battalions equipped with this Panzer IV-based tank destroyer. A Panzer IV Ausf H on the Eastern Front with its Schürzen intact. It bears the tactical number '505' and has a two-tone camouflage scheme. Hummel belonging to the 1st SS Panzer Division being transported by rail. Tarpaulins have been fitted to keep the rain out of the fighting compartment. The key and shield divisional insignia can just be seen on the front of the superstructure on the right-hand side. ## Chapter Nine ## Beyond the Seine The Panzer IV played a significant part in the Battle for Normandy. The most common type of panzer resisting the Allies in occupied France in 1944 was the Panzer IV Ausf H and Ausf J totalling around 750 tanks. Around two-thirds of the Panzer IV battalions were armed with the Ausf H and the rest with the newer Ausf J. With frontal armour of 80mm and the 75mm KwK 40 L/48 anti-tank gun, the Panzer IV provided the fighting backbone of the ten panzer divisions deployed to France (in all five army and five Waffen-SS divisions fielded it in Normandy). It, along with the Panther and Tiger tanks, gave the Germans a distinct advantage in tank-to-tank engagements during the battles in the Normandy bocage. Notably its gun had a 20 per cent higher muzzle velocity than that of the ubiquitous American-built M4 Sherman's 75mm gun, meaning it could punch through 92mm of armour at 500 yards, while the Sherman could only manage 68mm. In addition the Panzer IV proved remarkably reliable, maintaining consistently good operational rates. Normally the Panzer IV was allocated to the 2nd Battalion or II Abteilung of a panzer regiment, while the 1st was equipped with the Panther, although there were a number of exceptions in France. In the case of the 9th Panzer Division the 1st Battalion of its Panzer Regiment 33 was equipped with Panzer IVs and both battalions of 21st Panzer's Panzer Regiment 22 were equipped with it. At the beginning of June 1944 the 2nd Panzer Division, deployed east of the Seine at the start of the campaign, had a total of ninety-eight Panzer IVs on its strength. By early July the division still had eighty-five of them in the field with another eleven in the workshop. The 9th Panzer Division, based in the south of France, arrived in the Normandy in early August with a total of eighty-two Panzer IVs. The 21st Panzer Division, already in Normandy from the start, had a total of 104 Panzer IVs, including six old Ausf G and six even older Ausf B or C with the short 75mm gun. None of the latter seems to have been upgraded and lacked Zimmerit and Schürzen. Before D-Day one of the Ausf B/C dubbed 'Heidi' was photographed in St Martin de Fresnay, south-east of St Pierre-sur-Dives, where its crew were happily shopping for Camembert cheese. It is not clear if this was an authorized use of official military equipment or simply a PR exercise. On 24 May 1944 another fourteen Panzer IVs were despatched to 21st Panzer, but it is unlikely that they had arrived by early June. During the battle for Normandy another thirty were sent to the division including three command tanks. The final ten gun tanks probably did not arrive in time to take part in the fighting. Panzer Lehr Division, initially north-west of Orleans, had ninety-nine Panzer IVs. It was sent another eleven Mk IVs as replacements on 8 July 1944. Following heavy fighting with the Americans, by 22 August the division had just ten left. When the 116th Panzer Division Windhund, north of Paris, was committed to the battle for Normandy in late July it had 86 Panzer IVs. Its other armoured fighting vehicles include three older Panzer IVs with the short 75mm gun. Following the German retreat and the fighting at St Lambert the division was only able to retrieve four Panzer IVs from the battlefield. The Waffen-SS panzer divisions committed to Normandy were also equipped with the Panzer IV. The 1st SS Panzer Division Leibstandarte Adolf Hitler, east of Brussels, mustered forty-two Panzer IVs in its 1st Tank Battalion. A further eight were in for repair. Deliveries during June amounted to another fifty-three tanks. After being sent to Normandy by late July the division was able to field sixty-one Panzer IVs. The 2nd SS Panzer Division Das Reich by the beginning of June had fifty-four Panzer IVs, of which ten were in the workshop. Further deliveries of armour meant that the 2nd SS was to field a total of eighty-three Panzer IVs, which included the newer Ausf J. Many of these were lost in the Roncey pocket at the end of July, though some of the Mk IVs from 2nd SS managed to escape. The 9th SS Panzer Division Hohenstaufen had forty-eight Panzer IVs at the start of the campaign, but seven of these were in the shop. Its sister division 10th SS Frundsberg was able to deploy thirty-nine and by mid-August had only lost twelve. However, just eight Panzer IVs were available to hold the Americans at bay. The formidable 12th SS Hitlerjugend had an authorized strength of 101 Panzer IVs though only ninety-one were combat ready. By 10 August after much heavy fighting the division had just fifteen left. By 1944 the panzer divisions were largely relying on flak guns mounted on half-tracks for air defence, including the SdKfz 10/4 and SdKfz 7/1. In Normandy the Flakpanzer 38(t) using Czech-built chassis was in service instead of the Flakpanzer IV with the 2nd, 9th, Panzer Lehr and 1st SS Panzer Divisions. In theory eight Flakpanzer IV Möbelwagen were allocated to the anti-aircraft section of a panzer regiments headquarters' company. In July 1944 (on paper at least) Möbelwagens were assigned to the 12th SS and 116th Panzer Divisions. Very limited numbers of Wirbelwind also saw combat in Normandy. The lack of infantry divisions, which were held north of the Seine, meant the panzers bore the brunt of the fighting. By the beginning of July 1944 the unrelenting operational commitment of the panzers had taken its toll: 42 per cent of the Panzer IVs and 58 per cent of the Panthers were in the maintenance depots. Prior to Montgomery's Goodwood offensive on 18 July Panzer IVs of 21st Panzer along with Tiger tanks from Heavy Panzer Battalion 503 were caught in the Allied saturation bombing near Château de Manneville 10km east of Caen. The effects were devastating, with tanks simply tossed upside-down like they were toys. From a force of about fifty panzers over half were lost, many others suffering mechanical failures. Although Goodwood failed to breakthrough the incredibly tough German defences it contributed further to the attrition of the Panzer IVs in Normandy and helped pin them in the British sector. In August for the renewed counter-attack at Mortain against the Americans the Germans could only gather seventy-seven Panzer Mark IVs and forty-seven Panthers, roughly the same inadequate number that had been launched in the initial attack, which involved fifty-seven Panzer IVs and seventy Panthers. A few weeks later, unable to contain the American breakout, the German Army was in headlong flight and then trapped at Falaise and defeated. After the Battle for Normandy despite the presence of surviving panzers belonging to the SS at Arnhem, Montgomery was not put off launching Operation Market Garden that resulted in the disastrous battle for the Rhine crossing. Following the Panzerwaffe's mauling in Normandy by late 1944 the Panzer IV was in very short supply. As a result of continual battlefield attrition and the disruption caused by Allied bombing the panzer divisions struggled to field both a battalion of Panzer IVs and a battalion of Panthers. The 2nd and 11th Panzer and the 2nd SS and 9th SS Panzer Divisions each had two companies of StuG assault guns instead of Panzer IVs; the 9th and 116th Panzer Divisions had no Panzer IV at all, fielding instead three companies of StuGs. Other divisions had a single battalion of mixed Panzer IVs and Panthers. The second battalion had to be substituted by panzerjäger and sturmgeschütz units. To make up for such shortfalls, prior to Hitler's winter Ardennes offensive the 1st SS was supplemented by a battalion of heavy Tiger IIs, while the other divisions had to
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4839, 273, 37290, 187, 187, 34191, 5871, 7945, 327, 2552, 1668, 285, 1580, 840, 253, 12801, 273, 36210, 16500, 556, 644, 1669, 281, 10027, 285, 943, 10308, 885, 387, 1475, 11084, 10294, 407, 8330, 13, 3978, 1283, 15, 187, 187, 2042, 352, 46046, 352, 588, 320, 46002, 896, 281, 271, 28036, 273, 34581, 10294, 275, 4260, 14, 20443, 15, 1292, 326, 588, 320, 352, 323, 7236, 23003, 285 ]	additional cases were reported in the past 24 hours, putting Italy’s total case count at 86,498. Lombardy region and Emilia Romagna remain the hardest hit regions with 37,298 and 11,588 cases, respectively. There are 36,653 cases in home isolation, 26,029 hospitalized cases and 3,732 required intensive care. In related news, the International Olympic Committee and the Tokyo 2020 Organizing Committee announced that the Games of the XXXII Olympiad in Tokyo will be rescheduled to a date beyond 2020 but no later than summer 2021. Globally to date, more than 585,000 cases have been reported from 176 countries or regions and nearly 27,000 deaths have been recorded.Orbis, Rhineland-Palatinate Orbis is a municipality in the Donnersbergkreis district, in Rhineland-Palatinate, Germany. References Category:Donnersbergkreis Category:Palatinate (region)Ferrari Ignites Bologna - Web Exclusive The Bologna Motor Show in Italy came to life this week to the sound of a Ferrari F1 car. Fans of the team were able to see the car in action at the 37th annual auto show that features a number of motorsport legends. This year Giancarlo Fisichella drove the 2009 F60, which Fisichella drove that year when he stood in for the injured Felipe Massa. The driver and car got a warm welcome from the fans packing the grandstands despite the freezing conditions. Fisichella, who won this year's FIA World Endurance Championship alongside Gimmi Bruni in a Ferrari 458 GT2, also did four pitstop simulations for the spectators to enjoy. TEXAS COURT OF APPEALS, THIRD DISTRICT, AT AUSTIN NO. 03-13-00338-CV In re Eric Flores ORIGINAL PROCEEDING FROM TRAVIS COUNTY MEMORANDUM OPINION Relator Eric Flores, an inmate, has filed a pro se petition for writ of mandamus, asking this Court to compel an unspecified Travis County District Court to appoint a medical expert in an administrative proceeding that Flores has filed with the Texas Medical Board. The proceeding involves a claim by Flores that certain autopsy procedures conducted by the El Paso County Medical Examiner’s Office are illegal. Mandamus is an extraordinary remedy that issues only to correct a clear abuse of discretion or violation of a duty imposed by law when no other adequate remedy at law is available. See Walker v. Packer, 827 S.W.2d 833, 839 (Tex. 1992); Johnson v. Fourth Court of Appeals, 700 S.W.2d 916, 917-18 (Tex. 1985); State v. Walker, 679 S.W.2d 484, 485 (Tex. 1984). The relator has the burden to provide the Court with a record sufficient to establish his right to mandamus relief. See Walker, 827 S.W.2d at 837. Flores has failed to demonstrate that he is entitled to the extraordinary relief sought. See id. at 837-44. Accordingly, the petition for writ of mandamus is denied. See Tex. R. App. P. 52.8(a). __________________________________________ Bob Pemberton, Justice Before Justices Puryear, Pemberton and Rose Filed: June 7, 2013 2 The Venus Express spacecraft has spent eight productive years orbiting the planet Venus and is now ready to take the plunge. Its orbit is slowly being lowered and from Wednesday it will repeatedly dive in and out of the planet’s dense and harsh atmosphere, travelling deeper than it ever has before. It’s not known whether the spacecraft will survive the soaring temperatures or if its electrical components will be able to handle the strain. But whatever the outcome, valuable data will be obtained by the spacecraft’s engineers to help inform future planetary missions, along with a rare opportunity to investigate a previously unexplored territory of Venus. Time to take a chance Venus Express is the European Space Agency’s first mission to Venus and is currently the only spacecraft studying that planet, the second from our sun. It entered orbit in April 2006 for a mission that was due to last 500 days, or just over two Venus days as measured by the planet’s very slow rotation. After all this time – and a number of successful mission extensions – the spacecraft’s fuel gauge is now close to empty. So ESA has seized the opportunity to push the spacecraft into new territory. It will be sent to plough through the atmosphere of Venus to demonstrate the techniques of aerobraking – using a planet’s atmosphere to slow down a spacecraft. It’s a useful manoeuvre for getting into orbit around a planet without heavy reliance on rocket engines, which would require packing lots of fuel on board and increases the power needed to launch off Earth. Swinging high and swinging low It takes 24 hours for Venus Express to complete one highly elliptical orbit. The spacecraft soars 66,000km above the planet’s south pole before swinging around to skim the upper atmosphere just a few hundred kilometres above the north pole. After completing 500 days in orbit, Venus Express had mapped the entire planet twice over. The second pass filled in important data gaps missed the first time around and showed how things had changed from one long Venus day to the next. During this period, the spacecraft maintained a height between 250km to 400km above the north pole. To open up new science opportunities and extend the work of the spacecraft beyond its primary mission, its orbit was cautiously lowered to between 185km and 300km, in the first atmospheric drag experiment (ADE). This placed Venus Express in reach of the upper atmosphere of Venus. And on August 4, 2008, the spacecraft did indeed feel the effects and experienced a low level of atmospheric drag for the first time. Pedalling against sunlight Since then, over a dozen ADEs have been carried out, each one following a similar pattern. Venus Express is low on fuel because it routinely needs a boost to maintain its orbit. If left alone, the orbit falls into a natural decay which lowers the spacecraft towards the north pole by as much as 4km in each successive orbit. A number of factors are involved but the main effect is due to solar radiation. Sunlight is known to exert pressure – it’s the reason why comet tails always point away from the Sun. So when Venus Express travels towards the incoming solar radiation its orbital speed is reduced, just like trying to ride a bicycle into a headwind. At such times, the spacecraft’s orbit drops most quickly towards the north pole. ESA But at other times, Venus Express travels across the solar radiation, or in other words our cyclist pedals against a crosswind. This is relatively easier to manage. The spacecraft doesn’t slow down by as much and its descent towards the north pole is briefly stabilised. When this occurs, it’s the perfect time to hold off any orbital boosts and allow the spacecraft to slowly and carefully dip into the atmosphere. The spacecraft is the experiment The ADEs were perfect dress rehearsals for the major event occurring this week. During each one, Venus Express dipped into the atmosphere for just six minutes of its 24-hour orbit, and would repeat this for around ten days. On three occasions it dropped as low as 165km above the north pole, reaching into the upper ionosphere. Venus Express does not include an instrument capable of measuring the density of the atmosphere. Instead it uses its own reaction to the atmospheric drag it encounters. During the ADEs, the spacecraft’s two solar panels are oriented asymmetrically, so that one faces the incoming stream of atmosphere, while the other is turned by 90 degrees and presents itself edge on. As it’s buffeted by the weak atmosphere, the spacecraft experiences a torque. Stabilising reaction wheels work to compensate and maintain the spacecraft’s orientation. Just how much adjustment is needed translates into quite a precise estimate of the atmosphere’s density. Furthermore, the spacecraft’s trajectory is also meticulously tracked so that any changes brought about by atmospheric drag can also be determined and turned into a measure of density. Australia listens in In all previous ADEs, the safety of Venus Express has been paramount and the spacecraft was closely monitored by the two ground stations in the right location to track it at those critical moments: ESA’s New Norcia station in Western Australia and NASA’s Deep Space Network in Canberra. During an ADE, calculations would be made daily to determine the unique escape manoeuvre that would get Venus Express out of a bind and immediately raise its orbit. Venus Express was not allowed to experience levels of atmospheric drag that might comprise its safety. But that’s about to change – it’s now or never for Venus Express. Cloudy with a chance of annihilation Science operations concluded on May 16 and since then the orbit of Venus Express has been left to decay and should stabilise at around 130km by Wednesday, June 18. If it survives it will be boosted back to an altitude of 475km in mid-July. But that will be it for fuel reserves and
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30, 20, 16, 19, 1352, 1284, 271, 1650, 359, 1379, 370, 78, 30, 20, 16, 19, 1352, 7757, 13, 253, 7898, 994, 1658, 447, 403, 3413, 407, 1764, 2043, 92, 2132, 94, 187, 61, 6796, 464, 1588, 92, 41, 6922, 20, 16, 19, 1603, 805, 10, 15638, 2249, 2204, 61, 10423, 578, 85, 30, 18, 1990, 21, 1603, 81, 64, 85, 1035, 3124, 1572, 6677, 9, 81, 64, 85, 1035, 3124, 9679, 3353, 187, 61, 6796, 464, 1588, 92, 41, 6922, 20, 16, 19, 1603, 18, 10, 15638, 14, 4464, 81, 64, 20 ]	}^{(j)}(\theta)&=&\Big\|d_{m',m}^{(j)}(\theta)\Big\|^2.\end{aligned}$$ We shall use the map of numbers $m'$ and $m$ onto the numbers $1,2,\ldots,N$, $N=2j+1$ using the following rule $-j\Rightarrow 1,\quad -j+1\Rightarrow 2,\quad\ldots,\quad j \Rightarrow N.$ Thus, we can study the relation which can be obtained by considering the probability vector $\overrightarrow{p}=(p_1,p_2,\ldots,p_N)$, where $\sum\limits_{k=1}^{N}p_k=1$, $p_k\geq0$ hold. Hence, similarly to Sec. \[sec:1\] we can denote as $\widetilde{m}_{ik}$, $i,k\in\{1,2,\ldots N\}$. Fixing the index $k$ and mapping the index $i$ onto pairs $(\alpha(i),\beta(i))$ as in or we can write the entropy of the whole system in terms of $\widetilde{m}_{ik}\equiv\widetilde{p}_{\alpha(i),\xi(i)}^{(k)}$, i.e. $$\begin{aligned} \widetilde{\mathcal{H}}_{m}(12)&=&-\sum\limits_{\alpha=1}^{2}\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{\alpha(i),\xi(i)}^{(k)}\ln \widetilde{p}_{\alpha(i),\xi(i)}^{(k)}\\ &=&-\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\left(\widetilde{p}_{1,\xi(i)}^{(k)}\ln \widetilde{p}_{1,\xi(i)}^{(k)}+\widetilde{p}_{2,\xi(i)}^{(k)}\ln \widetilde{p}_{2,\xi(i)}^{(k)}\right)\\ &=&-\sum\limits_{i=1}^{N(N+1)}\widetilde{m}_{ik}\ln \widetilde{m}_{ik}\\ &=&-\sum\limits_{m'=-j}^{j}\Big\|d_{m',m}^{(j)}(\theta)\Big\|^2\ln \Big\|d_{m',m}^{(j)}(\theta)\Big\|^2.\end{aligned}$$ Analogically, the partial entropies can be written as $$\begin{aligned} \widetilde{\mathcal{H}}_{m}(1)&=&-\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{\xi(i)}^{(k)}(1)\ln \widetilde{p}_{\xi(i)}^{(k)}(1)\\ %&=&-\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\left(\widetilde{p}_{1,\xi(i)}^{(k)}+\widetilde{p}_{2,\xi(i)}^{(k)}\right)\ln \left(\widetilde{p}_{1,\xi(i)}^{(k)}+\widetilde{p}_{2,\xi(i)}^{(k)}\right)\\ %&=&-\sum\limits_{i=1}^{N(N+1)}\left(\widetilde{m}_{ik}+\widetilde{m}_{i+\frac{N+1}{2},k}\right)\ln \left(\widetilde{m}_{ik}+\widetilde{m}_{i+\frac{N+1}{2},k}\right)\\ &=&-\sum\limits_{m_1'=-j}^{-\frac{1}{2}(0)}\sum\limits_{m_2'=\frac{1}{2}(1)}^{j}\left(\Big\|d_{m_1'm}^{(j)}(\theta)\Big\|^2+\Big\|d_{m_2'm}^{(j)}(\theta)\Big\|^2\right)\\ &\cdot&\ln \left(\Big\|d_{m_1'm}^{(j)}(\theta)\Big\|^2+\Big\|d_{m_2'm}^{(j)}(\theta)\Big\|^2\right),\end{aligned}$$ $$\begin{aligned} &&\widetilde{\mathcal{H}}_{m}(2)=-\sum\limits_{\alpha=1}^{2}\widetilde{p}_{\alpha(i)}^{(k)}(2)\ln \widetilde{p}_{\alpha(i)}^{(k)}(2)\\ %&=&-\widetilde{p}_{1}^{(k)}(2)\ln \widetilde{p}_{1}^{(k)}(2)-\widetilde{p}_{2}^{(k)}(2)\ln \widetilde{p}_{2}^{(k)}(2)\\ %&=&-\left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{1,\xi(i)}^{(k)}\right)\ln \left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{1,\xi(i)}^{(k)}\right)\\ %&-&\left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{2,\xi(i)}^{(k)}\right)\ln \left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{2,\xi(i)}^{(k)}\right)\\ %&=&-\left(\sum\limits_{i=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{m}_{ik}\right)\ln \left(\sum\limits_{i=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{m}_{ik}\right)\\ %&-&\left(\sum\limits_{i=\frac{N}{2}+1 (\frac{N+1}{2}+1)}^{N (N+1)}\widetilde{m}_{ik}\right)\ln \left(\sum\limits_{i=\frac{N}{2}+1 (\frac{N+1}{2}+1)}^{N (N+1)}\widetilde{m}_{ik}\right)\\ &=&-\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}\Big\|d_{m',m}^{(j)}(\theta)\Big\|^2\ln\left(\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}\Big\|d_{m',m}^{(j)}(\theta)\Big\|^2\right)\\ &-&\sum\limits_{m'=\frac{1}{2}(1)}^{j}\Big\|d_{m',m}^{(j)}(\theta)\Big\|^2\ln\left(\sum\limits_{m'=\frac{1}{2}(1)}^{j}\Big\|d_{m',m}^{(j)}(\theta)\Big\|^2\right).\end{aligned}$$ The subadditivity condition for the matrix from the $SU(2)$-group is the following $$\begin{aligned} \label{15}&-&{\sum\limits_{m_1'=-j}^{-\frac{1}{2}(0)}\sum\limits_{m_2'=\frac{1}{2}(1)}^{j} \Bigg(S_{m_1',m}^{(j)}(\theta)P_{m_1',m}^{(j)}(\theta)^2+S_{m_2',m}^{(j)}(\theta)P_{m_2',m}^{(j)}(\theta)^2\Bigg)}\ln \left(S_{m_1',m}^{(j)}(\theta)P_{m_1',m}^{(j)}(\theta)^2 +S_{m_2',m}^{(j)}(\theta)P_{m_2',m}^{(j)}(\theta)^2\right)\\\nonumber &-&\!\!\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2 \ln\left(\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\right)-\!\!\!\!\sum\limits_{m'=\frac{1}{2}(1)}^{j}\!\!\!\!S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\ln \left(\sum\limits_{m'=\frac{1}{2}(1)}^{j}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\right)\\\nonumber &\geq&-\sum\limits_{m'=-j}^{j}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\Bigg(\ln\left(S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\right)\Bigg).\end{aligned}$$ The resulted inequality can be interpreted as the new inequality for the Jacoby polynomials. Examples of systems with spins $j=3/2$ and $j=2$ ------------------------------------------------ Let us consider the state with the spin $j=3/2$. As an example we take $m=3/2$. Hence, the partial entropies are determined by $$\begin{aligned} \widetilde{\mathcal{H}}_{3/2}(12)&=&-\sum\limits_{t=1}^{4}(p_t(\theta)\ln(p_t(\theta)),\\ \widetilde{\mathcal{H}}_{3/2}(1)&=&-((p_3
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13, 352, 369, 35747 ]	low that I wasn't sure if he was talking to me or to himself. I waited, stirring the pan as the milk began to simmer, and figured that if it _were_ me he was talking to, he'd let me know when he wanted an answer. "I thought that I knew her... and the woman that I loved would not have betrayed me so willingly." I took two white china cups and saucers from the cabinet and poured some milk into each one. "Maybe her need for revenge was greater than her need for human love," I said softly. "I do not think so," Senenmut said gravely, looking up at me for the first time. I didn't answer as I stirred a couple of spoonfuls of cocoa powder into one of the cups of milk and set it in front of him. I did the same for myself, then took the stool beside him. "Maybe you just didn't know her as well as you thought you did," I said, taking an exploratory sip of my drink—which was delicious—and trying not to burn the roof of my mouth at the same time. Senenmut watched me sip my drink, then looked down at his own cup of hot chocolate. "You said I could try yours first." I shrugged. "I lied. It's cocoa. I promise you you're not gonna want to share it, either." This made Senenmut smile, but only for a moment, then the smile disappeared as quickly as it had come. "Do you really believe that it is a good idea to bring Hatshepsut and her Minx to your home?" Senenmut asked, sniffing the cup of cocoa curiously before sipping it. "I don't think I have any choice," I said. "I either confront them here, where I have a little support, or at my tiny apartment, where I don't." Senenmut nodded and took another sip of cocoa. "This is very good." "Cocoa's the one thing I'm pretty good at not screwing up," I replied, pleased that Senenmut liked my little hot chocolate pick-me-up. We sipped our drinks in silence, each lost in our own thoughts. It was really nice not to be alone as I waited for Clio and Jarvis to summon Hatshepsut and her Minx. Out of nowhere, Senenmut said, "Do you trust Bast?" I picked up my cup and drank what was left of my hot chocolate then I stood up to put my cup and saucer into the sink. "No, I think she's up to something—and I also think she's got some kind of weird hold over Jarvis and my sister." Senenmut nodded. "Yes, I think that you are right, only—" He paused, thinking. "What? Go on," I said. Senenmut shook his head. "It may be nothing—" he started to say, but was interrupted by a faint knocking sound. Startled, I turned around to find Clio standing at the window in front of the kitchen sink, gesturing for us to come outside. "I think it's time," Senenmut finished instead, leaving me to wonder exactly what it was he was going to say before Clio interrupted him. As we left the safety of the kitchen—and the comfort of our hot chocolate—my Egyptian friend's comment about Bast stayed with me, scratching at my brain like an itch that wouldn't go away. twenty-six Clio was unusually quiet as Senenmut and I followed her across the grounds toward the cliff's edge, the roaring of the waves below us like white noise in my head. I guessed everyone was feeling kind of tense, because the usual joking banter Clio and I would've fallen into was replaced by silence as we moved toward the benches. I wrapped my arms around myself, my mohair sweater not even pretending to keep me warm. I realized I should've grabbed a jacket before we went outside, but I didn't think anyone would take too kindly to me running back to get one. It was already cold out—and the buffeting winds only made it worse, whipping the longer strands of my hair into my face, stuffing my mouth with the foul taste of dog drool and sweat. _Yuck!_ The only light came from the fullness of the moon, which hung round and distended above us, making me wonder what exactly it was we were about to give birth to by inviting Hatshepsut and her Minx to Sea Verge. Even though he _was_ acting kind of weird, I trusted Jarvis implicitly, and since he had signed off on the experiment, I wasn't worried about biting off more than we could chew. Still, once they _did_ arrive—and under false pretences, mind you—how they heck were we gonna contain them? The Minx in its Mustafa form had already proven to be a wily adversary—and I didn't know _what_ Hatshepsut would do once she laid eyes on her long-lost lover, Senenmut. Things could go to Hell in a handbasket pretty damn quickly if we weren't careful. Senenmut took my hand as we got closer to the cliff's edge—and my first thought was that he was just being friendly—but when he gave my fingers a metacarpal-crushing squeeze, I had to stifle a yelp. I looked over at him angrily, not sure what game he was playing at, but he merely shook his head, his eyes wide with fear. He indicated with his head, and I followed his gaze. Jarvis and Clio had encircled the benches with a fine white powder that I couldn't place but guessed was crushed bone. "What is it?" I hissed at Senenmut, but he only squeezed my fingers harder to shut me up as Clio turned to see what the trouble was. I flashed her a wide smile, which she seemed to accept. "All good," I said. "Just tripped over myself for a minute there." This got another harsh squeeze from Senenmut, who had slowed his pace down to half speed, pulling me with him as he decelerated. "Fine," I mumbled under my breath. "Don't tell me what's going on." But by then, I was starting to feel kind of nervous about the scene that lay ahead of us, too. I spied Jarvis standing just within the circle of bone powder over by the cliff's edge, Bast sitting primly on his shoulder. That was so _not_ a Jarvis move. Still, even with my growing misgivings, I forged ahead, glad that I at least had Senenmut in my corner. "What's with the circle?" I asked Clio as we neared our destination. "It's for the spell, silly girl," Clio replied. Her voice was light, but it worried me that she chose not to turn around and look at me when she spoke. Besides which, what seventeen-year-old girl living in the twenty-first century _ever_ used the term "silly girl" in reference to an older sibling? I would've expected that kind of terminology from Jarvis, but Clio? _Never_ —no matter _how_ many Paris Hilton reality shows she decided to watch. "I've never done a summoning spell before," I said, "but it seems kind of weird to have to use ground-up bones just to make what amounts to a toll-free long-distance call." Senenmut and I had reached the edge of the circle, but instead of following Clio inside it, we had each made an unconscious decision to stay as far away from the bone meal-covered part of the ground as possible. "You have to step inside the circle for the spell to work, Callie," Clio said, beckoning me forward. "I don't think so," I replied, my feet staying firmly where they were. "Why not, Calliope?" Jarvis said—using my given name again—as he reached up to stroke Bast's neck. "The spell won't work if you don't step into the circle." "Step into the circle," Clio said, more resolutely. "Yes, step into the circle," Jarvis chimed in. "Would you guys _please_ stop with all the repeating," I groaned. "You're giving me a headache." Senenmut squeezed my hand again, forcing me to look away from Clio and Jarvis. "What?" I hissed, annoyed. "Don't look them in the eye," he whispered. "Why?" He sighed. "You ask too many questions, Calliope Reaper-Jones. Just... don't do it." "Fine," I said, exasperated. Out of the corner of my eye, I saw Clio lean forward to whisper into Jarvis's ear. "Whatcha talking about?" I asked innocently, and they both quieted down instantly. I waited for one of them to answer me, but neither of them seemed inclined to speak. In the end, it was Bast
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407, 806, 8493, 432, 3915, 36, 281, 654, 2551, 3740, 568, 4909, 14, 15417, 27, 6795, 14, 10127, 13011, 27384, 20690, 870, 2551, 31, 285, 840, 9433, 253, 10295, 1320, 476, 320, 13657, 715, 271, 6425, 654, 2551, 3740, 568, 4909, 14, 15417, 27, 6795, 14, 10127, 13011, 1267, 36, 870, 2551, 31, 4227, 407, 247, 14189, 14, 2606, 5141, 15, 380, 3915, 36, 4227, 840, 556, 1979, 575, 1202, 4820, 92, 18372, 1603, 76, 3822, 187, 187, 29, 2551, 3740, 568, 4909, 14, 15417, 27, 6795, 14, 10127, 13011, 31455, 1605, 37713, 870, 2551, 31, 310, 19380, 14, 10984, 575, 683, 52, 1267, 2125, 1092, 1014, 672, 11096, 281, 14580, 342, 4869, 4248, 1740, 575, 683, 44, 54, 805, 62, 390, 281, 3019, 19, 44, 64, 19, 13, 20, 44, 64, 18, 16550, 4924, 14580, 575, 683, 12677, 47, 1012, 1092, 285, 1220, 17254, 275, 14189, 673, 327, 260, 25446, 575, 683, 12677, 47, 1012, 62, 285, 275, 673, 575, 5, 48, 9, 18, 15, 2945, 63, 76, 12, 78, 1009, 327, 2087, 14580 ]	Conference (MVMC) Ohio-Kanawha Valley Conference (OKVC) Potomac Conference (PC) Camps The West Virginia - Western Maryland Synod assists three camps: Camp Luther -- located at Camp Caesar in Cowen, West Virginia Caroline Furnace Lutheran Camp & Retreat Center -- in Fort Valley, Virginia Camp Melancthon --located at New Germany State Park in Grantsville, Maryland See also List of ELCA synods References External links Synod website Category:Evangelical Lutheran Church in America synods Category:Lutheranism in Maryland Category:1988 establishments in the United States--- abstract: 'We study the parameterized and classical complexity of two problems that are concerned with induced paths on three vertices, called $P_3$s, in undirected graphs $G=(V,E)$. In <span style="font-variant:small-caps;">Strong Triadic Closure</span> we aim to label the edges in $E$ as strong and weak such that at most $k$ edges are weak and $G$ contains no induced $P_3$ with two strong edges. In <span style="font-variant:small-caps;">Cluster Deletion</span> we aim to destroy all induced $P_3$s by a minimum number of edge deletions. We first show that <span style="font-variant:small-caps;">Strong Triadic Closure</span> admits a $4k$-vertex kernel. Then, we study parameterization by $\ell:=\|E\|-k$ and show that both problems are fixed-parameter tractable and unlikely to admit a polynomial kernel with respect to $\ell$. Finally, we give a dichotomy of the classical complexity of both problems on $H$-free graphs for all $H$ of order at most four.' author: - Niels Grüttemeier and Christian Komusiewicz title: 'On the Relation of Strong Triadic Closure and Cluster Deletion[^1]' --- Introduction ============ We study two related graph problems arising in social network analysis and data clustering. Assume we are given a social network where vertices represent agents and edges represent relationships between these agents, and want to predict which of the relationships are important. In online social networks for example, one could aim to distinguish between close friends and spurious relationships. Sintos and Tsaparas [@sintosL] proposed to use the notion of strong triadic closure for this problem. This notion goes back to Granovetter’s sociological work [@Granovetter73]. Informally, it is the assumption that if one agent has strong relationships with two other agents, then these two other agents should have at least a weak relationship. The aim in the computational problem is then to label a maximum number of edges of the given social network as strong while fulfilling this requirement. Formally, we are looking for an STC-labeling defined as follows. A labeling $L=(S_L,W_L)$ of an undirected graph $G=(V,E)$ is a partition of the edge set $E$. The edges in $S_L$ are called strong and the edges in $W_L$ are called weak. A labeling $L=(S_L,W_L)$ is an STC-labeling if there exists no pair of strong edges $\lbrace u, v \rbrace \in S_L$ and $\lbrace v, w \rbrace \in S_L$ such that $\lbrace u, w \rbrace \not \in E$. For any weak (strong) edge $\lbrace u, v \rbrace$ we refer to $u$ as a weak (strong) neighbor of $v$. The computational problem described informally above is now the following. <span style="font-variant:small-caps;">Strong Triadic Closure (STC)</span>\ Input: An undirected graph $G=(V, E)$ and an integer $k \in \mathbb{N}$.\ Question: Is there an STC-labeling $L=(S_L,W_L)$ with $\|W_L\| \leq k$? We call an STC-labeling $L$ optimal for a graph $G$, if the number $\|W_L\|$ of weak edges is minimal. The STC-labeling property can also be stated in terms of induced subgraphs: For every induced $P_3$, the path on three vertices, of $G$ at most one edge is labeled strong. Therefore, as observed previously [@KNP17L], <span style="font-variant:small-caps;">STC</span> is closely related to the problem of destroying induced $P_3$s by edge deletions. Since the graphs without an induced $P_3$ are exactly the disjoint union of cliques, this problem is usually formulated as follows. <span style="font-variant:small-caps;">Cluster Deletion (CD)</span>\ Input: An undirected graph $G=(V, E)$ and an integer $k \in \mathbb{N}$.\ Question: Can we transform $G$ into a cluster graph, that is, a disjoint union of cliques, by at most $k$ edge deletions? More precisely, any set $D$ of at most $k$ edge deletions that transform $G$ into a cluster graph, directly implies an STC-labeling $(E\setminus D,D)$ with at most $k$ weak edges. There are, however, graphs $G$ where the minimum number of weak edges in an STC-labeling is strictly smaller than the number of edge deletions that are needed in order to transform $G$ into a cluster graph [@KNP17L]. Due to the close relation between the two problems, there are graph classes where any minimum-cardinality solution for <span style="font-variant:small-caps;">Cluster Deletion</span> directly implies an optimal STC-labeling [@KNP17L]. In this work, we study the parameterized complexity of <span style="font-variant:small-caps;">STC</span> and <span style="font-variant:small-caps;">Cluster Deletion</span> and the classical computational complexity of both problems in graph classes that can be described by one forbidden induced subgraph of order at most four. #### Known Results. <span style="font-variant:small-caps;">STC</span> is NP-hard [@sintosL], even when restricted to graphs with maximum degree four [@KNP17L] or to split graphs [@konstantinidis_et_alL]. In contrast, <span style="font-variant:small-caps;">STC</span> is solvable in polynomial time when the input graph is bipartite [@sintosL], subcubic [@KNP17L], a proper interval graph [@konstantinidis_et_alL], or a cograph, that is, a graph with no induced $P_4$ [@KNP17L]. <span style="font-variant:small-caps;">STC</span> can be solved in ${\mathcal{O}}(1.28^k + nm)$ time and admits a polynomial kernel when parameterized by $k$. These two results follow from a parameter-preserving reduction to <span style="font-variant:small-caps;">Vertex Cover</span>, which asks if it is possible to delete at most $k$ vertices of a given graph such that the remaining graph does not contain any edge. This parameter-preserving reduction [@sintosL] computes the so-called Gallai graph [@Sun91; @Bang96] of the input graph and directly gives the above-mentioned running time bound. The existence of a kernel for parameter $k$ is implied by two facts: First, <span style="font-variant:small-caps;">Vertex Cover</span> admits a polynomial kernel for the number $k$ of vertices to delete [@Cyg+15; @DF13]. Second, <span style="font-variant:small-caps;">Vertex Cover</span> is in NP and <span style="font-variant:small-caps;">STC</span> is NP-hard. Hence, the <span style="font-variant:small-caps;">Vertex Cover</span> instance of size $\operatorname{poly}(k)$ which we obtain by first reducing from STC to <span style="font-variant:small-caps;">Vertex Cover</span> and then applying the kernelization can be transformed into an equivalent <span style="font-variant:small-caps;">STC</span> instance by a polynomial-time reduction. The STC instance then has size $\operatorname{poly}(k)$. <span style="font-variant:small-caps;">Cluster Deletion</span> is NP-hard [@SST04], even when restricted to graphs with maximum degree four [@KU12] or to $(2K_2,3K_1)$-free graphs [@GHN13], and solvable in polynomial time on cographs [@GHN13] and in time $O(1.42^k+m)$ on general graphs
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40, 15, 285, 309, 908, 281, 1790, 327, 253, 36118, 273, 253, 42107, 860 ]	aliens' had been concentrated in the Buffalo Stadium, a sports stadium in the south of Paris, and the'suspects' in the Roland Garros Stadium. On that morning, probably because of the shortage of transport, the _Préfecture_ had ordered the local police stations to direct _all_ arrested men to the Buffalo camp. But, as appeared on our arrival at that place, they had forgotten to inform the camp authorities at Buffalo of their changed dispositions. It was the usual French muddle. I was the first non-enemy alien to pass through the control bureau of the camp; when I put my passport on the desk and saw the official's surprised face, it all came to me in a flash. 'When and where were you arrested?' asked the official. 'In the Café Dupont, Place de la Convention, an hour ago.' I did not consciously have to reflect for a second for my anwers. The brandy did it for me—or that sly, hairy super-ape, the subconscious. The point is that normally I am a bad actor, and if I try to bluff at poker I am always caught. It was a very odd experience. 'Where is your _carte_ __ _d'identité_?' 'At home—10, rue Dombasle, seventh floor. That is why I have been arrested. I just went down to have coffee after lunch and left my _carte_ __ _d_'_identité_ __ in the flat; there was a round-up and they took me to the police station. I asked them to let me go home and fetch the _carte_ __ _d'identité_, __ but they wouldn't listen—they just shoved me into the car and here I am.' I __ _felt_ that I was absolutely convincing—the right mixture of polite indignation and honest-to-God stupidity. And all the time I watched my own performance and wondered. Normally I am the rather uninspired type of person; when writing, for instance, I have to sweat out every line with a conscious effort. It was indeed very odd. In the same dream-like exaltation in another age, a person would perhaps have heard voices and produced a mystic vision; now miracles had to happen at police officials' desks; but it was fundamentally the same process. The man behind the desk turned my passport over and looked at my other papers: Press card, the famous letters from Influential Persons, etc. Over his head, there was a clock on the wall, and it marked 4.30. 'All this is a quite amusing experience for a journalist, but the bother is that I have an appointment at five o'clock,' I said—that is, the brandy said, or the hairy ape. 'What sort of appointment?' 'Why—the daily Press Conference at the Ministry of Information.' (I had never been at the Press Conference and I had not written an article since the war—but I had kept the Press card.) 'That idiot Lamèche is always making a mess of things,' said the man behind the desk to his assistant; he fumbled irresolutely with my papers. Lamèche, I gathered, was the _commissaire_ _de_ _police_ of the XVth Arrondissement. Our escort had left immediately after delivering us. 'Look,' I said. 'I have got to be there at five. If you still have doubts, send a man to accompany me home in a taxi while I fetch my _carte_ __ _d'identit_ _é_ _._ __ You can give me an armed escort and even a machine-gun if you think it necessary.' Opposite the desk was the door that led into the camp—and once through that door there was no returning. I had it before my eyes and I knew it was a death-trap; and I knew that the slightest shadow of a false ring in my Voice would finish me. But it was not my own voice, and I trusted it entirely. 'No, I don't think that's necessary,' said the man behind the desk and handed my papers back with a smile. 'You are free, monsieur. Sentry, take monsieur to the entrance gate.' And to his secretary: 'Remind me to ring that idiot Lamèche when we are through with the others.' And to me:'_Au_ __ _revoir_, __ _monsieur._ Next time you had better carry your _carte_ __ _d'identité_ on you.' On the way to the gate I picked up my suitcase which I had left outside the entrance to the office. The sentry did not notice that there was anything wrong about that. At the gate I gave him five francs and asked him to get me a taxi. The taxi arrived. Exit Hyde, enter Jekyll. But only for a few minutes, while the taxi approached the Porte d'Orléans and the drumming in my chest calmed down. Then the blessings of the brandy began to evaporate and I began to realise the situation in which I was. The camp official would ring Lamèche, or whatever his name was; in half an hour or so the game would be up and the police at my flat—this time perhaps really with a tommy-gun. I knocked at the window pane and gave the driver another address. I knew that I would never see my flat again. Exit Jekyll, enter Hyde. But this time for good. ## V I had either to give myself up to the police or to go to ground, taking the risk of having to face a military tribunal if caught. I decided on the latter course. I still had some friends. Who these friends were, how they passed me on in turn, hiding me for one night each, and how they finally succeeded in obtaining for me a travelling permit to Limoges, where a fortnight later I ceased legally to exist, will be an amusing and moving story to tell at a time when the night has gone from Europe and acts of kindliness and solidarity no longer count as crimes. But still it is night; and from the moment when at the Porte d'Orléans I gave the taxi driver a certain address, the story has to move along a dotted line, until G. and I emerge from an overcrowded train at the railway station at the town of Limoges, famous for its manufacture of porcelain and its retired generals. Those first days of June in Limoges were like a short coming up for air before the final dive. The Battle of Dunkirk was still in progress, giving France a last respite. I felt safe from the police for at least a fortnight. The travelling permit which my friends had procured me was a most respectable-looking document, covered with all sorts of lovely rubber stamps in black and red—my heart jumped with pleasure whenever I looked at it. It enabled me to go to the local police and provisionally legalise my situation; my _carte_ __ _d_'_identité_, with the revealing 'E,' was officially lost. In due time, of course, the _Préfecture_ of Limoges would report my arrival to the _Préfecture_ of Paris and would receive instructions to arrest me; but, what with red tape and the administrative chaos, this could hardly be expected to happen for another fortnight or three weeks. So there was time to take a deep breath and think matters over—like a man who, crashing down a precipice and catching hold half-way of a clump of grass, sighs with relief until the roots give way under his weight, and he continues his plunge to the bottom. Limoges was on one of the main roads along which the stream of refugees flowed down from north to south. My memories of those last days of France are mainly of an acoustic nature: the never-ceasing polyphonic symphony of motor horns, the roaring and humming of the engines, the thundering of the heavy lorries on the roadway, the asthmatic rattle of old Citroëns, the neighing of horses and the crying of exhausted children, as the chaotic stream flooded through the town on its aimless course. Without interruption, all day and all night, the mechanised divisions of disaster passed by and the people in the streets stared at them; some pityingly, some with hostile contempt, some with anxiously thoughtful eyes, wondering when their turn would come to join the Great Migration to the South. For they had watched the growing of the stream from the first days, when it was no more than a rivulet with its sources far away in the north, in Holland and Belgium, and the cars still bore foreign markings; then in the days of Sedan it had suddenly swollen and on the number plates appeared the signs of the French provinces, M for the Département du Nord, N for the Pas de Calais; and nearer and nearer, X for the Somme, Y for Seine-et-Oise, until the first green buses from Paris appeared and for a few days nine out of ten number plates bore the fatal R of the capital; then even the R's thinned out and new sources of the stream opened up in Brittany and on the Loire. The number-plates on the cars told the dreadful tale of the steam-roller thundering down over France, and revealed the truth which the official communiqués still tried to hide. G. and I used to sit on the terrace of the Café
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247, 3885, 5599, 15, 309, 369, 247, 11745, 5599, 281, 1265, 342, 38039, 187, 187, 1909, 344, 5762, 13, 1869, 13, 285, 2540, 13, 17966, 6888, 253, 16228, 273, 253, 33005, 11656, 471, 27, 187, 187, 424, 18, 6019 ]	morning to some golf course in Virginia, and that he would wear the gas mask in the lake and retrieve the balls, and we'd split the money three ways._ _"Kerlin said, 'How do I stay down on the bottom?' I said, 'Oh, I've got that all worked out. What we will do is, you'll strip, and you'll be nude, but you'll wear my Washington Post newspaper bag, and we'll put barbell plates in the newspaper bag so that you'll stay on the bottom.'_ _"So we went out to this golf course, and all the way Kerlin was expressing some doubt. And Danly and I said, 'Have we ever failed? I mean, you're looking at a couple of guys...if you want to quit now, okay, but, you know, you're not in any future deals.'_ _"So we got out there at the crack of dawn. Kerlin was stripped, and we were dressed warmly. He was totally nude with a Washington Post newspaper bag on and all these barbell plates, and he started wading into the lake. Of course, he didn't know if he was stepping on snakes or golf balls or whatever. And then he got down and when he tugged on the rope, we pulled him back up. He said, 'I can't see anything.' We said, 'Don't worry about seeing anything, just grope around.' And he started to go back down._ _"But before his head went under, this truck came over the rise, carrying the guy that's going to fill up sand traps in the morning. He saw us and drove up, saying, 'What are you kids doing?' Danly and I were thinking fast. 'We're conducting an experiment for our high school physics class, sir.' Kerlin was nodding the whole time. So we had to get him out of the pond. The whole thing blew up on us."_ 21 Whatever happened to poor Kerlin, and however nude he actually was, a watered-down version of this story got around. It would be the last great Tom Sawyering of Warren's high school career. By now, however, he had made a small fortune: a glistening $5,000 heap, sticky with the newsprint from throwing more than five hundred thousand newspapers. Newsprint snowflakes made up more than half his snowball. Rich as he was, however, Warren meant to keep that snowball rolling.8 13* The Rules of the Racetrack _Omaha and Washington, D.C. • 1940s_ W arren's Dale Carnegie tests of behavior were handicapping: a mathematical experiment on human nature. The data he collected gave him the odds that Carnegie was right. This way of thinking was an extension of his childhood hobby of calculating the odds on the life expectancies of hymn composers. But his interest in longevity was no mere abstraction. Ernest Buffett, to whom Warren was extremely attached, had died in September 1946 at age sixty-nine, while the family was in Omaha campaigning for Howard's third term. Warren was sixteen. Of his four grandparents, only Stella, age seventy-three, remained alive, confined in the Norfolk State Hospital. Long before Ernest's death, Warren had been preoccupied with his own lifespan; these latest family events did nothing to ease his mind about either longevity or insanity. Warren's passion for handicapping, however, extended to many other subjects, and in an embryonic form had started much earlier—well before he even knew the meaning of the term—back when he was a little kid with marbles and license plates and bottle caps and a fingerprint kit for nuns. The art of handicapping is based on information. The key was having _more information than the other guy_ —then analyzing it right and using it rationally. Warren had first put this into practical use as a child down at the Ak-Sar-Ben racetrack, when his friend Bob Russell's mother introduced the boys to the world of pari-mutuel betting. Warren and Russ were too young to wager, but they quickly figured out how to make a buck. Amid the cigarette butts, beer slops, old programs, and hot-dog remnants in the grime and sawdust of the Ak-Sar-Ben floorboards were thousands of discarded tickets, peeping out like mushrooms on the forest floor. The boys turned themselves into truffle hounds. _"They call that'stooping.' At the start of the racing season you get all these people who'd never seen a race except in the movies. And they'd think that if your horse came in second or third, you didn't get paid, because all the emphasis is on the winner, so they'd throw away place and show tickets. The other time you would hit it big was when there was a disputed race. That little light would go on that said 'contested' or 'protest.' By that time, some people had thrown away their tickets. Meanwhile, we were just gobbling them up. We wouldn't even look at them when we were working. At night we'd go through them. It was awful; people would spit on the floor. But we had great fun. If I found any winning tickets, my aunt Alice, who didn't care anything at all about races, would cash them in for us, because they wouldn't cash them for kids."_ Warren wanted to go to the races all the time. When Mrs. Russell wasn't taking him, _"my dad would never go to the races,"_ says Buffett. _"He did not believe in the races."_ Instead, his parents let his great-uncle Frank, the oddball of the family, take him. Frank had long ago reconciled with Ernest and had eventually married a woman whom the family referred to as "the gold-digger."1 He had no particular interest in the horses, but he took Warren to Ak-Sar-Ben because his great-nephew wanted to go. At Ak-Sar-Ben, Warren had learned something about how to read the tip sheet, and it opened up a whole new world. Handicapping horses combined two things he was very, very good at: collecting information and math. It was not unlike counting cards at blackjack, except that the winning hand had four legs and ran around a track. Soon, he and Russ knew enough to put out their own tip sheet, the cannily named _Stable-Boy Selections_. _"We got away with it for a while. They weren't the hottest sellers in the world. I mean, a couple of little kids selling this thing we typed up in my basement on an old Royal typewriter. The limiting factor was carbons in those days. You could probably only get in five or so carbons. But I got on the Royal and Bob Russell and I doped out the horses and then we typed up this thing._ _"We were in the track, yelling, 'Get your Stable-Boy Selections!' But the Blue Sheet was the number-one tip sheet, and the racetrack was getting a commission on it. The Blue Sheet sold for a little more. At twenty-five cents, we were a cut-rate product. They shut down the Stable-Boy Selections fast because they were getting a cut on everything sold in the place except for us."_ When the Buffetts moved to Washington, D.C., the only plus for Warren was the chance to upgrade his handicapping skills. _"The one thing I knew about Congress was that Congressmen had access to the Library of Congress—and the Library of Congress had everything that had ever been written. So when we got to Washington, I said, 'Pop, there's just one thing I want. I want you to ask the Library of Congress for every book they have on horse handicapping.' And my dad said, 'Well, don't you think they're going to think it's a little strange if the first thing a new Congressman asks for is all the books on horse handicapping?' I said, 'Pop, who was out there at the county fairs stumping for your election? Who was down there at the packinghouses ready to get to the cops if something happened?' I said, 'And you're coming up for reelection in two more years. You're going to need me. So this is payoff time.' And he got me hundreds of books on horse handicapping._ 2 _"Then what I would do is read all these books. I sent away to a place in Chicago on North Clark Street where you could get old racing forms, months of them, for very little. They were old, so who wanted them? I would go through them, using my handicapping techniques to handicap one day and see the next day how it worked out. I ran tests of my handicapping ability day after day, all these different systems I had in my mind._ _"There are two kinds of handicappers. There are speed handicappers and class handicappers. Speed handicappers figure out the horse with the best times in the past. The fastest horse will win. Class handicappers feel that the horse that's run against ten-thousand-dollar horses and done well and now is running against the five-thousand-dollar horses will beat them. Because, they say, the horse runs just fast enough to win._ _"In horse racing it pays to understand both types of handicapping. But back then I was basically a speed guy. I was a quantitative guy to start with."_ As he tested, thought, and observed, Warren discovered the Rules of the Racetrack: 1.
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NSClassFromString(@"AVCaptureDevice"); if (captureDeviceClass!= nil) { if ([device hasTorch] && [device hasFlash]){ [device lockForConfiguration:nil]; if (flashIsOn) { [device setTorchMode:AVCaptureTorchModeOn]; [device setFlashMode:AVCaptureFlashModeOn]; oneOff.text=@"On"; [_flashButton setImage:[UIImage imageNamed:@"flash-on-button"]]; _flashButton.accessibilityLabel = @"Disable Camera Flash"; flashIsOn = NO; //define as a variable/property if you need to know status } else { [_flashButton setImage:[UIImage imageNamed:@"flash-off-button"]]; _flashButton.accessibilityLabel = @"Enable Camera Flash"; oneOff.text=@"Off"; [device setTorchMode:AVCaptureTorchModeOff]; [device setFlashMode:AVCaptureFlashModeOff]; flashIsOn = YES; } [device unlockForConfiguration]; } } } - (void)dealloc { [[self session] stopRunning]; [super dealloc]; } - (void)storeFlashSettingWithBool:(BOOL)flashSetting { [[NSUserDefaults standardUserDefaults] setBool:flashSetting forKey:kCameraFlashDefaultsKey]; [[NSUserDefaults standardUserDefaults] synchronize]; } @end A: Please check your device settings. Goto privacy ---> Camera ---> check setting for your app-----> turn it on Run the app. It works. Cheers A: Change your dealloc Method [self.captureSession removeInput:self.videoInput]; [self.captureSession removeOutput:self.videoOutput]; self.captureSession = nil; self.videoOutput = nil; self.videoInput = nil; Q: Strange internet issues When I try and use any form of the internet, such as, apt-get, npm, the browser itself, etc, it hangs and cannot connect. However, when I ping, it can resolve hostnames and gets replies! I can SSH to it from inside the local network too. I've been having this issue and I can't find the solution anywhere! I'm using the RPi B+ Model 1 if that helps A: The only time I have read about anybody having those kinds of errors the solution seems always to be to start with a fresh new copy of Raspian. But there is a better solution: To protect against wierdnesses like this I use Win32DiskImager to save.img files periodically when the system is running correctly. That way I can always restore my system back to a known good condition. I name the image files with the date, i.e. 2016-09-29.img This way it restores any customization I have made so I do not need to start fresh and try to remember everything I have done with the system since the original install. g(y) = 6y. Suppose 37o - 5o = 704. What is the lowest common multiple of o and g(2)? 132 Suppose -32 = -w - w. Suppose 0 = 2c - 4q - 12, c + 3q = 2q. Suppose 4 = -ci, i + 24 = z - i. What is the smallest common multiple of w and z? 80 Let c(j) = -j3 - j2 - j + 1. Let o(r) = 5r3 + 4r*2 + 10r - 9. Let n(b) = -6c(b) - o(b). What is the least common multiple of 8 and n(2)? 88 Calculate the least common multiple of -2 + 7/((-28)/(-24)) and 10. 20 Suppose -15 = -3f, -5v - 4f + 0f + 40 = 0. Let z(w) = -w + 0w - 5 - vw. Calculate the smallest common multiple of 18 and z(-5). 180 Let r = -40 - -60. What is the least common multiple of 6 and r? 60 Let t be (1/3)/((-1)/(-63)). Let s = 9 - 3. Find the common denominator of -65/3 and (s/t)/(4/(-22)). 21 Calculate the lowest common multiple of 6 and (-2408)/(-40) - (-1)/(-5). 60 Suppose 6 = l + 3. Let c(r) = r + 7. Calculate the lowest common multiple of ((-1)/(-2))/(l/54) and c(-6). 9 Let x = 32197/9 + -3570. Calculate the common denominator of x and 34/3. 9 Let a(l) = 6l3 - l2 + 2l - 9. Let q be a(6). Let u = q - 25343/20. Find the common denominator of u and 1 - ((-54)/(-40) - 0). 20 Let v = 229 + -173. Calculate the least common multiple of 14 and v. 56 Suppose -32 = -3v - v. Suppose 9j - 17 = -8. What is the lowest common multiple of j and v? 8 Find the common denominator of 19/10 and (-78)/(-60) - 1-1. 10 Find the common denominator of 145/12 and (118/6)/(40/12). 60 Calculate the lowest common multiple of 3 and (2/(-8))/(5/(-40)). 6 Let o = -4049/20 - -1019/5. What is the common denominator of -113/20 and o? 20 Suppose 3c - 6a + a = 51, 0 = c + a - 25. What is the smallest common multiple of -163/(-12)3 and c? 132 Suppose -5h = 10, 2m - 2h - 44 - 4 = 0. Let l = 22 + -4. What is the least common multiple of m and l? 198 Suppose 0 = 4d - 2d - 32. Calculate the lowest common multiple of d and 4. 16 Let c = 44445081785/602 + -73828995. Let j = c + -3/301. What is the common denominator of 7/2 and j? 2 Suppose -3n + 42 = 3s, -2s - 4n + 7n + 8 = 0. What is the smallest common multiple of s and 10? 10 Let s be (-30892)/(-8784) + 2/9. Let g = s + 2/183. Find the common denominator of g and 43/18. 36 Let m = -1065/28 + 114/7. Let x(n) = -753n - 1. Let i be x(2). Let l = i + 7492/5. Calculate the common denominator of m and l. 20 Find the common denominator of -5/2 and -1 + 105/12 + 2. 4 Let v(r) = r2 + 9r - 12. Let p be v(-10). Let w = 5 + p. Calculate the lowest common multiple of -1222/(-4) and w. 33 Let c(r) be the third derivative of r*5/60 + 7r*4/24 + 4r*2. What is the least common multiple of c(-8) and 8? 8 Let j = -5330/3 - -1798. What is the common denominator of -5/8 and j? 24 Let v be (-4 + (-2)/2)-1. Let y(g) = -g*3 - 12g*2 - 2g - 6. Let m be y(-5). Calculate the common denominator of -131/6 and m/(-66)v/(-3). 66 Let x be 7044((-1)/1)/1. Let t = x + 549389/78. Let n = -3/26 + t. Find the common denominator of n and 17/11. 33 What is the common denominator of 0/1 - (-35)/63 and -19/3? 9 Suppose -4k = -5k. Suppose k = -3a + 16 - 1, -a + 13 = 4y. What is the lowest common multiple of 6/(-4)*120/(-9) and y? 20 What is the common denominator of 125/6 and (2 - (-148)/(-112)) + 3?
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559, 818, 15, 1737, 310, 891, 9, 71, 6177, 187, 805, 187, 1466, 295, 9, 76, 10, 426, 428, 22, 11, 76, 424, 19, 428, 374, 11, 76, 559, 337, 15, 1281, 891, 9, 67, 10, 426, 428, 67, 424, 19, 559, 721, 11, 67, 428, 577, 15, 1281, 256, 320, 891, 9, 24, 481, 1281, 268, 9, 88 ]	metrics attributes. Metrics attributes are measurements used in software tests to locate potential problem areas within the software application. Different than a “bug,” metrics attributes are desired standards in the design and operation of the software application, rather than mistakes or errors in the functionality of the software application. Testing “good code” is not purely a consideration of error-free code; instead “good code” is considered for complexity, extensibility, modularity, readability, etc. Testing tools are often used to determine values of metrics attributes. Formulas may be used to calculate numerical values for particular metrics attributes. Metrics may be oriented towards a particular design or programming paradigm. For example, object-oriented metrics attributes are metrics designed specifically to evaluate the performance of object-oriented code. Examples of objected-oriented metrics attributes include Depth of Inheritance Tree (DIT), Number of Children (NOC), Coupling Between Objects (CBO), Weighted Methods per Class (WMC), Response for Class (RFC), Nesting Tree (NT), Message Passing Coupling (MPC), etc. Each metrics attribute, object-oriented or otherwise, provides different information as to quality of the object-oriented code; the information may relate to functions, classes, or an entire software system. For example, MPC is a measure of message passing among classes, indicating a measure of coupling between a class and an entire software system. Determining a value of MPC provides an indication of software application complexity. Although a measured value of a metrics attribute may be out-of-bounds (either high or low), the software application may not necessarily be flawed. Metrics attributes give guidance as to desired standards, but are not necessarily mandates. Many techniques may be used to determine values of metrics attributes. One such technique is static analysis. Static analysis is a process of examining source code or compiled code without executing the source code or compiled code. Static analysis is typically used to locate problem areas in the source code or compiled code, e.g., potential bugs, unnecessary complexity, or high maintenance areas. Several mechanisms (similar to compilers) are used to perform static analysis, e.g., lexical or binary scanning, parsing, semantic analysis, data flow analysis, etc. For example, after testing an object-oriented software application, a value of the MPC metrics attribute of Class X may be found to be high, indicating Class X is strongly coupled. Strongly coupled classes are closely tied together, so that modifications attempted to one class are more likely to affect the other class, should modification be required. In a typical scenario, the MPC metrics attribute, along with other metrics attributes, are compiled into performance reports and discussed with the management team. The management team suggests improvements to problem areas in the source code, e.g., to improve the message coupling of Class X. The improvements are communicated to the development team for resolution. There is a definite cost associated with time, money, resources (tools and people), and space expended to develop a software system using this process.Q: Repository pattern in MVC: controller code explanation What is the purpose of SudentRepository in this example? Why do I need one? public class StudentController : Controller { private IStudentRepository _repository; public StudentController() : this(new StudentRepository()) { } public StudentController(IStudentRepository repository) { _repository = repository; } A: I updated to actually include a specific question that I think you're getting at. The purpose of StudentRepository is to encapsulate interactions with persisted data. The Controller need not know if its stored in a db, flat file, in memory, etc. The reason you're injecting it in via an interface is because you may eventually have multiple implementations of that repository, and the interface is just a contract to ensure basic functionality across all implementations. This is called constructor injection (a type of dependency injection) in case you want to learn more. y) = 6y3 + 2y2 + y. What is t(z)? -5 Let c(v) = -v3 - v*2 + 2v + 2. Let o be c(0). Let w(y) = 4y3 + 2y - 5y3 - 2 - y2 + 2y*3 + y. Give w(o). 8 Suppose -3t = 3, 0j + 2j = -2t - 14. Let l(d) be the third derivative of -d4/24 - d3/6 + d2. Calculate l(j). 5 Let g(x) be the first derivative of -x + 1/2x*2 - 1 + 1/6x3. Let i(v) be the first derivative of g(v). What is i(-3)? -2 Let j be (-85)/15 - (-4)/6. Let d(z) be the first derivative of z3/3 + 3z2/2 - 3z + 2. What is d(j)? 7 Let a = 9 + -4. Let i = -7 - -14. Let v(b) = 3b + i - b2 - b + 0. Calculate v(a). -8 Suppose -3w - 30 = -3t, -w - 40 = -4t - 2w. Suppose -25 = 5c, -3c = -k - 4k + t. Let f(g) = g. Give f(k). -1 Suppose -g = 2g - 5v - 127, -4v - 86 = -2g. Let h be g/9 + 5/(-15). Let d(r) = r*3 - 3r*2 - 2r - 1. Calculate d(h). 7 Let u(q) = 8q. Suppose x - 5 = j, 4x = 5j + 4 + 20. What is u(x)? 8 Let n(c) = -c3 - 6c*2 + 8c + 6. Let k(a) = -a*2 + 8a - 7. Let z be k(8). What is n(z)? -1 Let y(m) = -m*3 + 5m*2 - 3m. Let k(n) = -3n3 + 16n*2 - 10n. Let d(q) = 2k(q) - 7y(q). What is d(2)? -2 Let v(p) = 3p + 4. Let w be (-2 + 0)/(4/10). Let g(r) = -3r + 10. Let o(f) = -f + 1. Let y(c) = g(c) - 6o(c). Let k(b) = wv(b) + 4y(b). Determine k(-4). 8 Let u(o) = 8o*2. Suppose 5w = w - 4. Give u(w). 8 Suppose -3 - 7 = -4c + 2f, c - 25 = 5f. Let b(z) be the first derivative of c - z2 + 1 + 0. What is b(1)? -2 Let d(j) be the first derivative of j4/4 + 4j3/3 - j2/2 + 4j - 18. Calculate d(-4). 8 Let x(v) = -v3 - 3 - 703v*2 + 698v*2 + 6v - 2v. Give x(-6). 9 Let q = -41 - -44. Let x(k) = 2k*2. What is x(q)? 18 Let a = -2 - -12. Suppose -3u + g + a = 0, u + 3g - 6 = -2u. Let y(h) = -h + u + 0h + 0. Give y(2). 1 Suppose -2n - 2 + 0 = 0. Let w(o) = -o*2 + 4o + 7. Let t be w(5). Let j(y) = -2y + 4 - t - 1. Calculate j(n). 3 Let l(z) = -z - 6 - 7 + 10. Calculate l(-2). -1 Suppose 0 = 4r - 3b - 17, -2b = r - 4b - 8. Suppose -3w + 5 = a - 6, w - 13 = ra. Let s(k) = k2 - 7k + 1. Calculate s(w). -9 Suppose -3c + 1 = -2n, -n + 3c + 10 = 3. Let f be 1(n + 6 + -3). Let i(k) = -k + 7. What is i(f)? 12 Let n(k) = -5k2 - 2k + 1. Let i(b) = -b*2 + 6b - 4. Let s be i(7). Let p(w
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281, 39175, 15, 380, 30156, 285, 253, 25219, 2829, 403, 642, 187, 5056, 254, 12258, 347, 2436, 1005 ]	I suppose the same thing is true in France as in America. Neither here nor there can you find equality of results. All you have a right to expect is equality of opportunity. II. The great symbol and instrument of this idea of equal opportunity in the United States is the common school. In every State of the Union provision is made for the education of the children at public expense. The extent and quality of this education, the methods of control, the standards of equipment, even the matter of compulsory or voluntary attendance, vary in different States and communities. But, as a rule, you may say that it puts within the reach of every boy and girl free instruction from the _a_-_b_-_c_ up to the final grade of a _lycee_. The money expended by the States on these common schools in 1905-1906 was $307,765,000,--more than one-third of the annual expenditure of the national government for all purposes, more than twice as much as the State governments spent for all other purposes. This sum, you understand, was raised by direct, local taxation. Neither the import duties nor the internal revenue contributed anything to it. It came directly from the citizen's pocket, at the rate of $3.66 a year _per capita_, or nearly $13 a year for every grown-up man. How many children were benefited by it? Who can tell? 16,600,000 boys and girls were enrolled in the public schools (that is to say, more than 70 per cent of the whole number of children between five and eighteen years of age, and about 20 per cent of the total population). The teachers employed were 109,000 men, 356,000 women. The average daily expenditure for each pupil was 17 cents; the average annual expenditure, about $25. In addition to this number there are at least 1,500,000 children in privately endowed and supported schools, secular or religious. The Catholic Church has a system of parochial schools which is said to provide for about a million children. Many of the larger Protestant Churches support high schools and academies of excellent quality. Some of the most famous secondary schools, like Phillips Exeter and Andover, St. Paul's, the Hill School, Lawrenceville School, are private foundations well endowed. These figures do not mean much to the imagination. Statistics are like grapes in their skins. You have to put a pressure upon them to extract any wine. Observe, then, that if you walked through an American town between eight and nine in the morning, and passed a thousand people indoors and out, more than two hundred of them would be children going to school. Perhaps twenty of these children would turn in at private schools, or church schools. But nine-tenths of the little crowd would be on their way to the public schools. The great majority of the children would be under fourteen years of age; for only about one child out of every twenty goes beyond that point in schooling. Among the younger children the boys would outnumber the girls a little. But in the small group of high-school children there would be three girls to two boys, because the boys have to go to work earlier to earn a living. Suppose you followed one of these groups of children into the school, what would you find? That would depend entirely upon local circumstances. You might find a splendid building with modern fittings; you might find an old-fashioned building, overcrowded and ill-fitted. Each State, as I have said before, has its own common-school system. And not only so, but within the State there are smaller units of organization--the county, the township, the school district. Each of these may have its own school board, conservative or progressive, generous or stingy, and the quality and equipment of the schools will vary accordingly. They represent pretty accurately the general enlightenment and moral tone of the community. Wealth has something to do with it, of course. People cannot spend money unless they have it. The public treasury is not a Fortunatus' purse which fills itself. In the remote country districts, the little red schoolhouse, with its single room, its wooden benches, its iron stove, its unpainted flagstaff, stands on some hill-top without a tree to shadow it, in brave, unblushing poverty. In the richer cities there are common school palaces with an aspect of splendour which is almost disconcerting. Yet it is not altogether a question of wealth. It is also a question of public spirit. Baltimore is nearly as large and half as rich as Boston, yet Boston spends about three times as much on her schools. Richmond has about the same amount of taxable property as Rochester, N.Y., yet Richmond spends only one-quarter as much on her schools. Houston, Texas; Wilmington, Delaware; Harrisburg, Pennsylvania; Trenton, New Jersey; New Bedford, Massachusetts; and Des Moines, Iowa, are six cities with a population of from 80,000 to 100,000 each, and not far apart in wealth. But their public-school bills in 1906 varied as follows: Des Moines, $492,000; New Bedford, $472,000; Harrisburg, $304,000; Trenton, $300,000; Wilmington, $226,000; and Houston, the richest of the six, $163,000. If you should judge from this that the public schools are most liberally supported in the North Atlantic, North Central, and Far Western States, you would be right. The amount that is contributed to the common schools per adult male inhabitant is largest in the following States in order: Utah, $22; North Dakota, $21; New York, $20; Colorado, $20; Massachusetts, $19; South Dakota, $19; Nebraska, $17; and Pennsylvania, $16. The comparative weakness of the common schools in the South Atlantic and South Central States has led to the giving of large sums of money by private benevolence, the Peabody Fund, the Slater Fund, the Southern Education Fund, which are administered by boards of trustees for the promotion of education in these backward regions. The Spirit of America strongly desires to spread, to improve, to equalize and coordinate, the public schools of the whole country. Is it succeeding? What lines is it following? Where are the changes most apparent? First of all, there is a marked advance in the physical equipment of the common school. In the villages and in the rural districts the new buildings are larger and more commodious than the old ones. In many parts of the country the method of concentration is employed. Instead of half a dozen poor little schoolhouses scattered over the hills, one good house is built in a central location, and the children are gathered from the farmhouses by school omnibuses or by the electric trolley-cars. Massachusetts made a law in 1894 requiring every township which did not have a high school to pay the transportation expenses of all qualified pupils who wished to attend the high schools of neighbouring towns. In many States text-books are provided at the public cost. In the cities the increased attention to the physical side of things is even more noticeable. No expense is spared to make the new buildings attractive and convenient. Libraries and laboratories, gymnasiums and toilet-rooms, are provided. In some cities a free lunch is given to the pupils. The school furniture is of the latest and most approved pattern. The old idea of the adjustable child who could be fitted to any kind of a seat or desk, has given way to the new idea of the adjustable seat and desk which can be fitted to any kind of a child. School doctors are employed to make a physical examination of the children. In a few cities there are school nurses to attend to the pupils who are slightly ailing. Physical culture, in the form of calisthenics, military drill, gymnastics, is introduced. Athletic organizations, foot-ball clubs, base-ball clubs, are encouraged among the boys. In every way the effort is apparent to make school life attractive, more comfortable, more healthful. Some critics say that the effort is excessive, that it spoils and softens the children, that it has distracted their attention from the serious business of hard study. I do not know. It is difficult for a man to remember just how serious he was when he was a boy. Perhaps the modern common-school pupil is less Spartan and resolute than his father used to be. Perhaps not. Pictures on the wall and flowers in the window, gymnastics and music, may not really distract the attention more than uncomfortable seats and bad ventilation. Another marked tendency in the American common school, at least in the large towns and cities, is the warm, one might almost say feverish, interest in new courses and methods of study. In the primary schools this shows itself chiefly in the introduction of new ways of learning to spell and to cipher. The alphabet and the multiplication table are no longer regarded as necessities
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37470, 2929, 432, 2057, 3786, 11462, 2929, 390, 5795, 37470, 2929, 3580, 15, 187, 187, 12236, 1984, 5593, 27, 374, 15, 22, 3, 57, 20, 15, 22, 3, 380, 32880, 40011, 3120, 2953, 5098, 476, 320, 2326, 187, 187, 11837, 3239, 310, 2624, 581, 387, 247, 673, 1955, 281, 253, 2060, 414, 273, 253, 2953, 4910, 285, 256, 3006, 327, 253, 3120, 15, 380, 1232, 3936, 690, 4465, 673, 13, 533, 310, 973, 4409, 352, 7296, 352, 310, 760, 436, 2408, 273, 673, 642, 4465, 22852, 29095, 390, 2341, 403, 12845, 275, 253, 2403, 273, 436, 2199, 984, 352, 310, 1160, 432, 6313, 1966, 1612, 15844, 309, 9012, 281, 4266, 670, 841, 32622, 342, 619, 1966, 1612, 43387, 309, 717, 278, 962, 272, 689, 1051, 1281, 434, 923, 604, 352, 24094, 15, 8247, 281, 253, 9400, 14, 7243, 512, 253, 7223, 403, 15978, 2624, 597, 403, 39214, 285, 22377, 3033, 512, 2366, 275, 1355, 39657, 15, 187, 187, 3039, 368, 897, 247, 9140, 3120, 513, 368, 871, 752, 6569, 281, 634, 1711, 9140, 8364, 32, 1310, 253, 4657, 2506, 626, 761, 21724, 731, 368, 476, 1900, 5321, 731, 323, 441, 24457, 1310, 323, 5913, 1921, 10430, 441, 634, 8364, 285, 26246, 310, 562, 273, 253, 1953, 428, 309, 6888, 436, 13103, 747, 4660, 387, 378, 461, 22900, 253, 643, 1388, 15, 309, 2427, 2819, 323, 436, 2714, 2715, 273, 308, 1406 ]	: 100.0%; height: 100.0%" ></div> <div class="region matched" style="left: 0.0%; top: 0.0%; width: 100.0%; height: 100.0%" ></div> </div> <h5>Mask:</h5> <img src="mask.png" /> <h5>Greyscale, masked:</h5> <img src="grey.png"> <ul> <li>Maximum pixel intensity: 255 <li>threshold=10 </ul> <h5>Non-black pixels in region:</h5> <img src="non_black.png" /> </div> </body> </html>Preoperative computed tomography imaging in the management of impacted mandibular third molars. The purpose of this study was to examine the role of preoperative computed tomography (CT) imaging of the inferior alveolar nerve (IAN) for patients at increased risk for nerve injury during mandibular third molar (M3) extraction. To address the research purpose, the investigators enrolled a sample composed of subjects who presented for mandibular M3 extraction and had panoramic radiographic signs interpreted as being associated with an increased risk for inferior alveolar nerve injury. All subjects had preoperative CT imaging studies done to ascertain the position of the IAN with respect to M3. The predictor variable was the preoperative assessment of risk for IAN injury based on panoramic imaging. The outcome variable was the preoperative assessment of IAN injury risk after reviewing the CT studies. We documented the number of IAN injuries. Descriptive statistics were computed as indicated. The sample consisted of 23 patients who had bilaterally impacted wisdom teeth. The sample's mean age was 26 +/- 6 years (range: 18-48 years); 69.6% of the patients were female. After reviewing the panoramic radiographic, 80.4% of M3s were classified as having an increased risk for IAN injury. Upon examining the CT imaging, 32.6% were classified as high risk for IAN injury. After reviewing all imaging studies, 71.7% of the teeth in the sample were extracted. Intraoperative IAN visualization occurred in 21.2% of the cases. At 1 week postoperative, 3 patients had dysesthesia (9.1%); none had a permanent nerve injury. In this small series of patients, the additional information provided by 3-dimensional imaging changed the majority of patients from increased risk for nerve injury to low risk for nerve injury.Quilt patterns and Sunbonnet Sue are our passion here at Prairie Cottage Corner. Click the link to the right, to view and purchase our products. Join us and see our many free items and instructions on how to quilt, applique' and embroider. Got your cup of tea and a scone? Let's visit. Please "FOLLOW" us and leave a comment or two. We love to hear from you. We're going to have a lot of fun stitching and visiting. Translate Friday, October 18, 2013 New Quilt Patterns for Christmas and Winter "Dashing" is one of our newest quilt wall hanging patterns for winter and Christmas. It's fun to decorate these little projects. With this one, I found some lovely brass bells for the harness of the horse. They really jingle. These models were machine quilted by Lise Ott at Experience Quilts! quilt shop in Odessa, WA. This is a pattern for the less-experienced quilter wanting to learn applique' techniques and a little piecing. The directions in all these new patterns are complete for one wanting to learn. These are good patterns for classes in quilting. The projects are small, usually under a yard in dimension, and the shapes are quite simple. The patterns even include the embroidery stitches needed to do the embellishments. These patterns include instructions for fusible web applique' and freezer paper applique'. The corner of the blanket is blowing out behind as the pony trots swiftly on, weighted with a little bead and some stem stitching. Below, is the center block for "Midnight Feast", a small wall hanging done in violet batiks, for the most part. Winter is a hard time for some of our little forest friends. On this frigid night, some bunnies receive a present from Mr. Snowman! He's all decked out for the season. Here's some of the detail work, below, and a complete picture of the center block with borders and snowballs (above). We used some sequin-like leaves for Mr. Snowman's decorations. "Twas the Night" is the name of our third winter decorative quilt. The pattern includes the words to Clement Moore's poem as well as a recipe for old-fashioned Sugar Plums (seen dancing over the child's head). Mom reads to her daughter, warm and cozy. Here's the whole piece. The blocks for these quilts are simple and the patterns include all the directions needed to assemble them. We hope you enjoyed this preview. You can purchase these Leaf Wreath Wall Decoration Pattern Google+ Badge Holidays to Love FREE Fons and Porter Log Cabin Ebook! Download Your Free Log Cabin Quilting Pattern eBook from Fons & Porter's Love of Quilting Now! Many quilters love free log cabin quilting patterns because of their honored history. This free eBook from Fons & Porter's Love of Quilting features three different type of free log cabin quilting blocks: chevron log cabin quilt blocks, courthouse steps quilt blocks and traditional log cabin quilt blocks. This free eBook also outlines how simple a log cabin quilting pattern can be from the first step of selecting a block style down to choosing a setting for your blocks. Whatever type of log cabin quilt block you choose, this free eBook from Fons & Porter will show you how simple learning how to make a log cabin quilting pattern can be! QuiltWoman Craftsy Followers - I follow those who follow me....that way, we can visit..... December Banner ON SALE NOW! $3 - Sue's getting all ready for the Christmas Holiday! Google+ Followers Sign up to receive new posts as soon as they're written..... Please refrain from copying.... Please refrain from copying pictures or text from our blog without written permission, except recipes. Pictures and text are the exclusive property of Prairie Cottage Corner unless explicitly offered as a free gift to all. Thank you for your attention to this important caution.Hot Topics: THIS WEEK’S HIGH SCHOOL FOOTBALL SCHEDULE San Dimas High School and head coach Bill Zernickow, looking to win a second consecutive CIF-Southern Section title, begins its season by hosting Monrovia on Friday. The 2014 prep football season begins Thursday. (Keith Birmingham Pasadena Star-News)--- title: 'Using external libraries' --- Coming soon... Pages Tuesday, April 19, 2011 Product Spotlight: Address Books Have you ever just stepped over the magazine subscription cards at the store? Take a second and think of how many of these cards are discarded as "trash" to everyone at the store... Or all the ones that clutter your home and recycling bin since every magazine seems to need at least 8 of them... We have put these cards to good use in a mini address books. :) Now every time we go to the grocery store I get super excited to "clean-up" the magazines some. In fact, the silver lining to my ridiculously long appointment last week was that I got a ton of magazine subscription cards once I ransacked all of the magazines and organized everything in boredom. It is a really fun instant gratification item to collect!!! These pocket size address books pack plenty of space to keep all your addresses in this ever expanding digital world where some still like snail mail. Each address book is made inside either a discarded metro/transit card or gift card. Inside the card and a thicker back cover there is a range of (20)magazine subscription cards from a variety of magazines. In the back there are some "blank" pages for notes that are made with recycled paper from either previously printed paper or alternative recycled paper products. Address book measures: 2.5"X3.5" The NYC metro card address books can be seen Each page is cut one at a time due to the individuality of the address fields and sizing on the card. The process takes some extra time, but is well worth it considering it is only this amount of time no extra fossil fuels or energy are utilized in the making of this project because it is made from pure human power!!! I laugh to myself about these shirts with my human power slogan I am mulling over... Let's see if it sticks. Back to the topic- Once all the pages are individually cut they are punched and spiral bound all together in small batches. When you use a gift card do you know what happens to your old gift cards? If the store doesn't recycle them you can always save them for us ;) If for whatever reason sending us your cards and junk is out of the question - I discovered this awesome new station at Bust Buy the other day. I went looking for this special version of Tron
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One of the few places in Jinghong with an English-speaking staff, Meimei Café serves Western and Chinese favorites, as well as great coffee and juices. Known for: burgers; coffee; nice atmosphere. _Average main: Y45_ _2 Menglong Lu, Jinghong_ _0691/216–1221_ _No credit cards_. Mekong Café (湄公咖啡馆 _Méigōng kāfēiguǎn_ ) $ \| FRENCH \| Opened by a Frenchman who was once a hotel chef and his Chinese wife, Mekong Café is a favorite with all sorts of travelers. Backpackers, expats, couples as well as locals gather on its large front and back patios to enjoy afternoon dessert, delicious French cuisine, Chinese classics, or simply a drink to recover from the Jinghong heat. Known for: view; pizza; offers travel advice. _Average main: Y30_ _F1–104 Kingland International, Menglong Lu, Jinghong_ _0691/216–2395_ _www.mekongcafe.cn_. h Hotels Anantara Xishuangbanna Resort & Spa (西双版纳安纳塔拉度假酒店 _Xīshuāngbǎnnà ānnàtǎlā dùjìa jiǔdiàn_ ) $$$$ \| RESORT \| FAMILY \| On the banks of the Luosuo River, this luxury resort is in Menglun, about 60 km (37 miles) from Jinghong. Pros: perfect service; great views; sparkling pool. Cons: expensive; service is inconsistent; remote. _Rooms from: Y2000_ _Country Road 009, Menglun_ _691/893–6666_ _xishuangbanna.anantara.com_ _80 rooms, 23 villas_ _Breakfast_. Dai andYi Ethnic Minorities s Dai Related to Thais and speakers of languages belonging to the Tai-Kadai family, the Dai seem much more Southeast Asian than Chinese. In China they are primarily located in the Xishuangbanna, Dehong, and Jingpo regions of southern Yunnan, but can also be found in Myanmar, Laos, and Thailand. They practice Theravada Buddhism, the dominant form of Buddhism in Southeast Asia. The linguistic, cultural, and religious connections with Southeast Asia give Dai-inhabited regions a decidedly un-Chinese feel. Within China, they are most famous for their spicy and flavorful food and their Water Splashing Festival (water is used to wash away demons and sins of the past and bless the future). Many grow rice and produce such crops as pineapples, so villages are concentrated near the Mekong (Lancang) and Red (Honghe) rivers. The Dai population here has ebbed and flowed with China's political tide, and many are now returning after the turmoil of the 1960s and '70s. Yi Descendants of the Qiang people of northwestern China, the Yi (aka Sani) are scattered across southwestern China in Yunnan, Sichuan, and Guizhou provinces as well as Guangxi Zhuang Autonomous Region. The largest concentration of the more than 6½ million Qiang descendants are in Sichuan's Liangshan region. They live in isolated, mountainous regions and are known for being fierce warriors. Notable traits include their syllabic writing system, ancient literature, and traditional medicine—all of which are still being used today. The Yi also sport extravagant costumes that vary according to geographical region. Massive black mortarboard-style hats, blue turbans, ornate red headdresses, and other headwear complement brilliantly colored vests and pants. Their language is part of the Tibeto-Burman language family and similar to Burmese. Some Yi also live in Vietnam, where they are called the Lolo. Crown Hotel (皇冠大酒店 _Huángguàn dà jiǔdiàn_ ) $ \| HOTEL \| In the heart of Jinghong, the Crown Hotel has several low-slung buildings in a parklike setting with a lily-leaf-shape swimming pool. Pros: central location; night market nearby; good value. Cons: tired rooms; too few English-speaking staff; noisy. _Rooms from: Y350_ _70 Mengle Dadao, Jinghong_ _0691/219–9888_ _121 rooms_ _No meals_. Yourantai (悠然台 _Yōurán tái_ ) $$ \| RESORT \| The "Terrace of Serenity" more than lives up to its name. Pros: excellent atmosphere; gorgeous setting; amazing mattresses. Cons: minimum stay required; steps to climb; remote. _Rooms from: Y1280_ _2 Galan North Rd., Jinghong_ _138/8793–4096_ _www.yourantai.com_ _No credit cards_ _6 rooms_ _Breakfast_. b Shopping On Zhuanghong Lu in the northern part of town, there's a handicrafts market filled with Burmese jade jewelry and goods from Vietnam and Thailand. Assume that much of it is counterfeit. There is a small but vibrant night market on Mengla Lu outside the Crown Hotel. Genuine Pu'er tea can be safely bought from the tea shop in the Golden Zone hotel. # Side Trips from Jinghong s Sights Ganlan Basin (橄榄坝 _Gǎnlǎn bà_ ) FOREST \| One of the more scenic areas of Xishuangbanna is this valley 37 km (23 miles) from Jinghong. Locals still live in bamboo huts in the beautiful rain forest. The area is famous in Yunnan for its tropical flowers and its millions of butterflies. _Jinghong_. Sanchahe Nature Reserve NATURE PRESERVE \| One of China's first serious attempts at ecotourism, the 900-acre Sanchahe Nature Reserve is home to wild elephants. Two hours north of Jinghong, the park also features a butterfly farm and a cable car that offers breathtaking views. Lodging is in "tree houses" about 25 feet above ground—a unique place to spend a night. _Jinghong_. Xishuangbanna Tropical Botanical Garden (西双版纳热带植物园 _Xishuāngbǎnnà rèdài zhíwùyuán_ ) FOREST \| The nearest large town in the area, Menglun, is the location of China's largest botanical garden. With a gorgeous setting on a peninsula in the Luosuo River, the garden holds more than 13,000 tropical and subtropical plant species and a section of dense, unspoiled tropical rain forest. A museum tells about the local flora and fauna, as well as the humans that have inhabited the region. Families enjoy the humid and fragrant air of the tropics, picnicking in pavilions, and observing rare plants and animals. Visits can take anywhere from a few hours to an entire day (there are restaurants and places to stay overnight). Electric buses help you explore, and hop-on, hop-off tickets are available for Y100. TIP → Buses only run until 6 pm, so start at the eastern park and make your way back toward the entrance. Menglun is about 60 km (37 miles) east of Jinghong, a trip that takes about 90 minutes by bus. Or you can take a cab. _Menglun_ _Y100_. Yiwu (易武 _Yì wǔ_ ) TOWN \| Once one of the starting points of the ancient tea and horses trade route to Tibet, this village has an Old Town featuring the houses of the "tea lords" of yesteryear. The Old Town is hidden away behind the school on a hill and makes for very pleasant investigation for an hour or two. Yiwu's higher altitude also means that it's a great way to get away from the Jinghong heat. All around the area are tea plantations you can stroll in. Several buses to Yiwu leave from Jinghong daily. _Yiwu_. # WELCOME TO SICHUAN AND CHONGQING TOP REASONS TO GO Emeishan: Hike 10,000 feet to the top of one of China's holy mountains and a UNES
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1239, 1078, 247, 2608, 2173, 581, 15, 2635, 347, 247, 2969, 2608, 368, 476, 760, 3630, 285, 897, 14604, 4367, 342, 271, 1211, 2462, 18999, 6, 2908, 15, 187, 187, 3074, 2608, 3562, 1980, 30557, 32067, 7139, 476, 320, 13603, 407, 11287, 11922, 432, 253, 9823, 44, 48406, 11465, 313, 7836, 15, 3081, 3877, 387, 253, 990, 481, 187, 5035, 671, 1359, 476, 309, 13542, 3334, 247, 5522, 327, 9823, 44, 48406, 313, 14877, 481, 187, 2214, 253, 13232, 273, 29867, 13, 1060, 457, 84, 247, 5740, 13, 849, 281, 5386, 247, 1980, 2745, 57, 31309, 5202, 432, 9823, 44, 48406, 13, 342, 260, 8048, 6790, 7109, 32067, 61, 347, 1650, 27, 187, 187, 46736, 27, 187, 6826, 969, 281, 253, 773, 16560, 84, 668, 10334, 275, 253, 7533, 11126, 24711, 44, 48406, 27921, 668, 17414, 582, 3609, 253, 9617, 260, 8048, 6790, 7109, 32067, 4615, 285, 5532, 327, 773, 21605, 668, 327, 253, 2406, 1930, 273, 253, 3497, 15, 2732, 326, 368, 1364, 969, 22906, 253, 401, 6577, 35, 285, 4931, 5731, 253, 5981, 4367, 15, 187, 12094, 1386, 313, 12563, 1060, 27, 347, 14991, 823, 253, 5234, 1969, 15787, 2262, 187, 31141, 275, 614, 89, 32067, 1969, 328, 15905, 14, 9723, 30, 68, 8048, 6790, 7109, 32067, 13, 3560, 407, 275, 614, 89, 32067, 1969, 11183, 14, 71, 2109, 67, 15, 1310, 368, 452, 440, 40539, 247, 8266, 13, 23000, 13194, 275, 614, 89, 32067, 1969, 78, 10294, 1825, 15, 380, 1969, 49737, 5234, 476, 320, 2879, 13, 347, 973, 15, 187, 2042, 368, 513, 417, 878, 253, 10269, 749, 26687, 10542, 13, 253, 3126, 4778, 2462, 18999, 6, 1364, 320, 22269, 598, 15, 187, 5872, 253, 11534, 5202, 260, 8048, 6790, 7109, 32067, 61, 812, 15792, 320, 16737, 15, 187, 187, 14087, 5838, 187, 34, 12662, 806, 27, 496, 15755, 13798, 431, 368, 476, 1511, 7392, 2462, 23807, 6, 342, 2462, 23807, 6, 299, 15, 72, 15, 2462, 6989, 14729, 7739, 1893, 368, 476, 923, 281, 534, 1318, 253, 4903, 5645, 327, 634, 985, 15, 187, 40675, 9299, 253, 12616, 773, 249, 9823, 44, 48406, 627, 457, 84, 407, 4284, 642, 1980, 30557, 32067, 5202, 8038, 668, 575, 275, 253, 1953, 310, 417, 2032, 15, 9823, 44, 48406, 11323, 3139, 2067, 7139, 762, 2462, 6989, 23912, 6, 285, 275, 14991, 4438, 671, 281, 2462, 3074, 17104, 23912, 6, 313, 249, 253, 1563, 253, 9823, 44, 48406, 1850, 45455, 3249, 806, 2262, 187, 187, 1628, 6989, 6155, 39919, 2462, 2946, 3233, 33760, 24711, 44, 48406, 4713, 4149, 13544, 187, 1628, 6989, 3233, 39919, 2462, 12599, 2946, 3233, 33760, 24711, 44, 48406, 4713, 4149, 13544, 313, 17480, 7464, 37156, 10, 390, 2462, 6989, 23912, 6, 4713, 12599, 29559, 31, 4713, 12332, 5128, 13544, 24711, 44, 48406, 4713, 4149, 13544, 313, 27390, 7464, 31302, 13, 253, 11559, 654, 12599, 29559, 31, 285, 654, 12332, 5128, 31, 403, 3448, 7976, 10, 187, 7483, 275, 14991, 4438, 908, 773, 18170, 6155, 668, 285, 773, 18170, 3233, 39919, 2462, 3074, 17104, 23912, 33760, 24711, 44, 48406, 4713, 4149, 13544, 313, 17480, 7464, 37156, 10, 390, 2462, 3074, 17104, 23912, 6, 4713, 12332, 5128, 13544, 24711, 44, 48406, 4713, 4149, 13544, 313, 27390, 7464, 31302, 13, 253, 2876, 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5497, 18, 9, 66, 426, 5296, 13, 708, 67, 10, 990, 187, 50274, 1545, 5497, 19, 9, 66, 13, 270, 426, 5296, 10, 990, 187, 50274, 1545, 5497, 20, 9672, 66, 10, 990, 187, 50274, 1545, 5497, 21, 9, 66, 13, 475, 67, 13, 708, 68, 10, 990, 187, 50274, 1545, 5497, 22, 9, 66, 13, 475, 67, 13, 260, 10, 990, 187, 50274, 1545, 5497, 23, 9, 66, 13, 475, 67, 13, 260, 13, 708, 69, 10, 990, 187, 50274, 1545, 5497, 24, 9, 66, 13, 270, 426, 5296, 13, 475, 68, 13, 277, 13, 708, 70, 10, 990, 187, 50274, 1545, 6429, 18, 4464, 66, 582, 708, 67, 10, 5296, 3857, 247, 990, 535, 50274, 1545, 1408, 187, 50272, 8271, 64, 11969, 9, 17, 13, 1332, 20805, 78, 17, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 9, 18, 13, 1332, 20805, 78, 18, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 9, 19, 13, 1332, 20805, 78, 19, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 1490, 18, 13, 1332, 20805, 6972, 18, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 1490, 19, 13, 1332, 20805, 6972, 19, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 1490, 18, 13, 1332, 20805, 6972, 20, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 1490, 19, 13, 1332, 20805, 6972, 21, 481, 15752, 10, 187, 50272, 8271, 64, 11969, 1490 ]	see Integrating Local Additions, at time of writing for recent MiKTeX 2.9 (but the included images are from an older version, seemingly MiKTeX 2.5, and slightly different, cf. also http://docs.miktex.org/2.5/manual/localadditions.html ). The denomination there is “User-Managed TEXMF Directory” (see also additional note at the very end of this answer). Anyway, here an alternative description: Create a folder somewhere on your computer – with an important exception. It must not be a subfolder of your MiKTeX installation (it worked this way in older MiKTeX versions, but was changed for security reasons). Avoid as far as possible spaces in the path, it is a potential risk for malfunction. For use with MiKTeX portable the folder must be, of course, on the same drive as the MiKTeX installation, it will be saved as relative path. Here I will use c:\localtexmf. This folder must be TDS compliant (see thereto A Directory Structure for TeX Files); MiKTeX will complain, if not. What you need, depends on what you want to install into this directory, at least a tex\latex subtree should be sufficient. You will go safe, if you mimic the structure of the (itself TDS compliant) MiKTEX tree, but binaries can directly go into a subfolder c:\localtexmf\bin. Now, using the GUI: In the Start Menu go to the MiKTeX entry and open the settings – if you act as admin respectively “Settings (Admin)”, of course. The “MiKTeX Options” window will open. Go to the “Roots” tab. Click on “Add” and choose c:\localtexmf\. If there are more than one local directory, one can choose the search order with the “Up” and “Down” buttons. Now the almost most important part: Go to the “General” tab and click there on “Refresh FNDB” (FNDB = File Name Data Base). In some cases, especially if new fonts are installed, one has to press also the “Update Formats” button. If you’d forget this step, all earlier steps would be done to no purpose. Otherwise, using the command line (as admin always add the switch --admin): Execute initexmf --register-root=c:\localtexmf, followed by initexmf --update-fndb (shorter: initexmf -u). (In every step you can add the switch --verbose to get more information about, what happens.) Remark: For compatibility reasons there’s also the older switch --user-roots=<local-texmf-dir>, what according to initexmf --help registers user root directories, I assume also in administrative mode, but in http://docs.miktex.org/manual/initexmf.html it is not mentioned any more, so I must guess. In the case, a bin subfolder for binaries was created, it should be registered in the environment variable %PATH% before the binaries subtree of MiKTeX own installation, see e.g. How To Manage Environment Variables in Windows XP or a third-party tool like Env-Man or RapidEE. Then you need a system restart to take effect. An issue, that cannot be solved: A system wide environment variable, set by an admin, is always read before a user specific one. Then as a simple user you can only write and use batch files with an own %PATH% included. All user created local texmf trees can be disabled by temporary removing from the MiKTeX roots (cf. additional note at the end). See also How can I manually install a package on MiKTeX (Windows). For the sake of completeness, here’s a description, how to remove a local TeXMF tree from MiKTeX, with c:\localtexmf\ as example: GUI: Go again to the “Roots” tab in the settings (“MiKTeX Options” dialogue), select the directory c:\localtexmf\, and click on “Remove” on the lower side of the window. After that you must again refresh the FNDB and perhaps update the format files. Command line (also here: as admin add the switch --admin): Execute initexmf --unregister-root=c:\localtexmf, followed by initexmf --update-fndb. If you have uninstalled a font, additionally execute initexmf --mkmaps. The --verbose switch can be added, as well. If you do not need the bin subfolder anymore, the environment variable %PATH% must be cleaned up. Then the folder tree c:\localtexmf\ could safely be deleted. Additional Note A hint first: In Command Prompt you can type echo %Variable% with %Variable% e.g. %Userprofile%. So you can see to which value the variables expand on your system. Precisely the phrase “in MiKTeX there’s by default no local texmf tree installed” in the question is not true. MiKTeX adds itself several trees under %UserProfile% and in admin mode also to %AllUsersProfile% (in the following the MiKTeX denomination comes first): “UserConfig”: %AppData%\MiKTeX\<version>\ “UserData”: %LocalAppData%\MiKTeX\<version>\ (since Windows Vista) or %UserProfile%\<Local Settings>\<Application Data>\MiKTeX\<version>\ (until Windows XP, the strings <Local Settings> and <Application Data> are language dependent) only in admin mode used “CommonConfig” and “CommonData”: %AllUsersProfile%\MiKTeX\<version>\ (since Windows Vista) or %AllUsersProfile%\<Application Data>\MiKTeX\<version>\ (until Windows XP, the string <Application Data> is language dependent) The actual paths you can see with the GUI in the “MiKTeX Options” window under the “Roots” tab or with the command line interface by executing initexmf --report. Disadvantages of all these local trees: They can only be changed on installation, cf. Changing the location of auto-installed packages in MiKTeX, and they cannot be disabled (by temporary removing from the MiKTeX roots). For additional information see Difference between administrative and user mode of MiKTeX. A capacitor is a passive two-terminal electrical device used to store energy within an electric field, and contains at least two electrodes separated by a dielectric region. The capacitance of a capacitor is proportional to the surface area of the electrodes, and inversely proportional to the thickness of the dielectric region. Some examples of capacitors include deep trench (DT) capacitors and metal-insulator-metal (MIM) capacitors. DT capacitors are formed directly within a substrate, whereas MIM capacitors are formed within a back end of line (BEOL) metallization stack.class Base def foo() :base end end class Derived < Base def foo() :derived end end class Interpreter attr_accessor :ret def do_a() @ret += "there, "; end def do_d() @ret += "Hello "; end def do_e() @ret += "!\n"; end def do_v() @ret += "Dave"; end Dispatcher = { "a" => instance_method(:do_a), "d" => instance_method(:do_d), "e" => instance_method(:do_e), "v" => instance_method(:do_v) } def interpret(string) @ret = "" string.each_char {\|b\| Dispatcher[b].bind(self).call } end end assert 'demo' do interpreter = Interpreter.new interpreter.interpret('dave') assert_equal "Hello there, Dave!\n", interpreter.ret end assert 'Method#arity' do Class.new { attr_accessor :done def initialize; @done = false; end def m0() end def m1(a) end def m2(a, b) end def mo1(a = nil, &b) end def mo2(a, b = nil) end def mo3(a) end def mo4(a, b, &c) end def mo5(a, b, c) end def mo6(a, b, c, &d) end def mo7(a, b = nil, *c, d, &e) end def ma1((a), &b) nil && a end def run assert_equal(0, method(:m0).arity) assert_equal(1, method(:m1).arity) assert_equal(2, method(:m2).arity) assert_equal(-1, method(:mo1).arity) assert_equal(-2, method(:mo2).arity) assert_equal(-1, method(:mo3).arity) assert_equal(-2, method(:mo4).arity) assert_equal(-
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20631, 187, 187, 424, 16324, 264, 387, 27, 367, 1240, 606, 25593, 30164, 86, 32760, 20460, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 13925, 5413, 42597, 7061, 16015, 20460, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 29160, 5413, 500, 1205, 4530, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 2313, 29547, 1401, 44, 264, 1240, 25593, 26386, 1952, 18232, 76, 33259, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 13269, 5413, 530, 7675, 353, 14776, 16015, 20460, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 30768, 29547, 1401, 37315, 606, 263, 25593, 329, 2503, 606, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 13269, 5413, 378, 2788, 262, 611, 307, 86, 32760, 20460, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 32720, 5413, 530, 7675, 443, 4894, 518, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 32745, 29547, 1401, 43, 1368, 263, 25593, 26386, 1952, 367, 261, 606, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 13269, 5413, 10118, 261, 16015, 20460, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 2313, 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15, 11027, 2222, 2417, 15, 709, 9312, 1184, 2429, 13751, 273, 475, 41, 4556, 475, 5168, 4788, 66, 11, 432, 7009, 968, 792, 23799, 285, 475, 41, 4556, 475, 81, 8855, 16520, 11, 432, 611, 10442, 6736, 8451, 13, 29797, 36375, 1403, 27544, 13, 285, 2361, 326, 253, 3417, 452, 2074, 2133, 1979, 285, 497, 374, 15, 24, 6, 34249, 275, 21588, 19, 40525, 13, 3738, 597, 858, 417, 10018, 475, 41, 4556, 475, 5168, 4788, 66, 11, 8, 84, 21488, 3168, 13977, 327, 475, 41, 4556, 475, 81, 8855, 16520, 4556, 496, 4499, 13, 597, 2361, 326, 13751, 273, 475, 41, 4556, 475, 5168, 4788, 66, 11, 432, 7009, 968, 792, 23799, 285, 253, 4577, 475, 41, 4556, 475, 5168, 4788, 66, 11, 432, 36375, 1403, 27544, 403, 854, 15, 22, 6, 34249, 275, 21588, 19, 40525, 15, 187, 187, 8354, 2534, 30968, 5950, 347, 475, 41, 4556, 475, 5168, 4788, 66, 11, 403, 2330, 342, 1264, 378, 1042, 84, 13, 378, 15930, 27, 2446, 35, 25, 20777, 13, 378, 15930, 27, 2446, 35, 25, 22000, 13, 285, 378, 15930, 27, 2446, 35, 3245, 740, 15, 4731, 579, 290, 342, 19995, 1162, 355, 15, 1254, 2041, 15, 11027, 2222, 2417, 15, 709, 9312, 5413, 253, 1264, 378, 1042, 84, 3176, 281, 2723, 281, 25231, 4811, 2470, 1470, 577, 1084, 2041, 15, 11027, 2222, 2417, 15, 72, 5525, 910, 709, 14, 881, 568, 926, 2536, 7874, 749, 28956, 403, 25048, 762, 475, 41, 4556, 475, 5168, 4788, 66 ]	represent the same species (i.e. H. c. labuanensis) or two different species. IUCN status: Least Concern Recorded at: Pahang: Krau Wildlife Reserve \[[@pone.0179555.ref011], [@pone.0179555.ref041], [@pone.0179555.ref042]\], Tasik Chini \[[@pone.0179555.ref043]\], Kuala Atok, National Park \[[@pone.0179555.ref044]\], Bukit Ibam, Kemasul, Jengka, Klau Besar, Kenong and Gunung Aais \[[@pone.0179555.ref100]\]; Terengganu: Pasir Raja, Dungun \[[@pone.0179555.ref015]\], Tasik Kenyir \[[@pone.0179555.ref069]\]; Negeri Sembilan: Pasoh Forest Reserve \[[@pone.0179555.ref045]\], Gunung Angsi Forest Reserve \[[@pone.0179555.ref100], [@pone.0179555.ref101]\], Berembun Forest Reserve \[[@pone.0179555.ref101]\]; Perlis: Wang Kelian State Park \[[@pone.0179555.ref050]\]; Selangor: Ulu Gombak \[[@pone.0179555.ref054], [@pone.0179555.ref101]\], Air Hitam Forest Reserve \[[@pone.0179555.ref055]\], Semangkok Forest Reserve \[[@pone.0179555.ref101]\]; Melaka: Lata Bujang Forest Reserve \[[@pone.0179555.ref056]\], Unspecified \[[@pone.0179555.ref068]\]; Johor: Endau- Kluang Forest Reserve and Endau-Kota Tinggi Forest Reserve \[[@pone.0179555.ref056]\], Gunung Panti and Labis Forest Reserve \[[@pone.0179555.ref100]\]; Kedah: Ulu Muda Forest Reserve \[[@pone.0179555.ref057]\], Bukit Hijau \[[@pone.0179555.ref100]\]; Kelantan: Air Panas-Gua Musang, \[[@pone.0179555.ref061]\]; Perak: Temenggor Lake \[[@pone.0179555.ref069]\], Kledang Saiong Forest Reserve, \[[@pone.0179555.ref100]\]; Pulau Pinang: Bukit Panchor \[[@pone.0179555.ref100]\]. H. cervinus forages in forest understory and roosts in limestone caves and crevices amongst boulders in very large colonies of up to 100,000 individuals \[[@pone.0179555.ref011], [@pone.0179555.ref014]\]. *Hipposideros cineraceus* Blyth, 1853 Hipposideros cineraceus Blyth, 1853: 410; near Pind Dadan Khan, Salt Range, Punjab, PAKISTAN (W. Theobold, Esq., collector; Type unknown) \[[@pone.0179555.ref126]\]. Common English name: Ashy Roundleaf Bat Barcode Index Number: A DNA barcode (BM460-04) recorded as H. cf. cineraceus was collected in Pahang, Peninsular Malaysia and associated with the BIN, BOLD:AAI8259 ([Fig 4](#pone.0179555.g004){ref-type="fig"}). Remarks: Murray et al. \[[@pone.0179555.ref125]\] reported two forms of H. cineraceus sensu lato from Peninsular Malaysia. A specimen from Perak, Peninsular Malaysia had a large forearm (42.9 mm), echolocated at 152 kHz and showed a high divergence (9.2--15.1%) in ND2 mtDNA from other specimens; while a smaller specimen from Pahang, Peninsular Malaysia (forearm = 39.3 mm) echolocated at 144 kHz and showed 10.4--12.2% divergence in ND2 mtDNA. This is congruent with Khan et al. \[[@pone.0179555.ref032]\] who discovered an average divergence of 8.7% in cytochrome b mtDNA among specimens of H. cineraceus sensu lato from Krau Wildlife Reserve. Four BINs are associated with DNA barcodes named as H. cineraceus on BOLD ([Fig 4](#pone.0179555.g004){ref-type="fig"}). Our NJ analysis ([Fig 4](#pone.0179555.g004){ref-type="fig"}) did not cluster the DNA barcodes from Peninsular Malaysia and Borneo (BOLD:AAI8259) with other DNA barcodes of H. cineraceus from Vietnam, Laos and Borneo but clustered the barcodes more closely to H. atrox (BOLD:ACE5015 and BOLD:ACE6229) from Peninsular Malaysia instead. According to Kingston et al. \[[@pone.0179555.ref011]\], H. cineraceus resembles H. bicolor/atrox closely but is distinct with a smaller body size and a slightly raised bump at the internarial septum. In addition, the average echolocation frequency for H. cineraceus is 144 kHz and for H. atrox is 142 kHz. Further analyses including more specimens from across the region are required to examine the status of the bats recorded as H. cineraceus in Peninsular Malaysia. Consequently, we tentatively retained the name in this checklist. IUCN status: Least Concern Recorded at: Pahang: Krau Wildlife Reserve \[[@pone.0179555.ref011]\], Fraser Hill Forest Reserve \[[@pone.0179555.ref056]\], Jengka \[[@pone.0179555.ref100]\]; Kedah: Pulau Langkawi \[[@pone.0179555.ref023]\], Ulu Muda Forest Reserve \[[@pone.0179555.ref057]\]; Selangor: Ampang \[[@pone.0179555.ref023]\], Bukit Kutu Wildlife Reserve \[[@pone.0179555.ref051]\], Ulu Gombak \[[@pone.0179555.ref052]\]; Johor: Pulau Pisang \[[@pone.0179555.ref023]\], Labis Forest Reserve \[[@pone.0179555.ref100]\]; Perak: Temengor Forest Reserve \[[@pone.0179555.ref046]--[@pone.0179555.ref048]\], Royal Belum State Park \[[@pone.0179555.ref048]\]; Kelantan: Gunung Reng and Gua Musang \[[@pone.0179555.ref062]\], Gunung Stong State Park \[[@pone.0179555.ref100]\]; Melaka: Unspecified \[[@pone.0179555.ref068]\]; Terengganu: Bukit Dendong \[[@pone.0179555.ref097]\]. H. cineraceus roosts in caves or similar structures such as culverts, often with other Hipposideros species \[[@pone.0179555.ref011], [@pone.0179555.ref014], [@pone.0179555.ref023]\]. *Hipposideros diadema* \[Geoffroy, 1813\] Rhinolophus diadema Geoffroy, 1813: 263, pls. 5, 6; Timor Island, INDONESIA (Péron and Lesueur, collector; MNHN 918) \[[@pone.0179555.ref127]\]. Hipposideros diadema \[[@pone.0179555.ref008]\]. Common English name: Diadem Roundleaf Bat Barcode Index Number: BOLD:AAB8310 (7 DNA barcodes from Peninsular Malaysia; [Fig 4](#pone.0179555.g004){ref-type="fig"}) Remarks: Murray et al. \[[@pone.0179555.ref125]\] compared specimens of H. diadema from Peninsular Malaysia and H. pelingensis from Kabaena Island, Southeast Sulawesi, and reported that the species have similar body size and were 2.7% divergent in ND2 mtDNA, although they did not observe H. diadema's distinctive white spots on H. pelingensis. In contrast, they reported that specimens of H. diadema from Peninsular Malaysia and the smaller H. diadema from Sulawesi are 8.5% divergent in ND2 mtDNA. DNA barcodes recorded as H. diadema are associated with three BINs, BOLD:AAB8308, BOLD:AAB8309, and BOLD:AAB8310. Congruent with Murray et al. \[[@pone.0179555.ref125]\], the three BINs appear to correspond to geographical regions ([Fig 4](#pone.0179555.g004){ref-type="fig"}). Four subspecies are recognised under H. *diadema
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326, 597, 497, 19185, 275, 45003, 335, 34088, 5123, 15, 329, 2014, 9417, 273, 42688, 6221, 598, 281, 2233, 3041, 273, 731, 15, 187, 187, 48851, 13, 45003, 335, 34088, 5123, 403, 594, 25806, 12956, 281, 275, 31861, 32243, 14516, 326, 597, 16753, 642, 4322, 281, 7497, 15, 496, 958, 13, 359, 476, 897, 45003, 335, 34088, 5123, 281, 776, 5750, 15, 45273, 476, 5386, 253, 3488, 742, 11078, 3320, 432, 253, 14781, 285, 8171, 352 ]	ote, or something with a more leisurely pace, this island delivers an abundance of hiking options suitable for all abilities. From coastal strolls to steep ascents, you can take things at your own pace while enjoying the natural beauty and wildlife along the journey. 4. A wealth of watersports With over 200 kilometres of beautiful coastline, it’s no surprise that watersports heavily feature in the list of things to do on the island. Besides the typical doughnut rides and banana boats you find on the main resort beaches, you’ll also find numerous water-based fun to be had during your time in Lanzarote. Whether you fancy roaming the shoreline above by boat or marvelling at the tropical marine life while scuba diving, Lanzarote is awash with reasons to hit the beach and dive right in. 5. Something for everyone One of the most important reasons to get active in Lanzarote is that regardless of your interests, you’re sure to find something that inspires you to get out and about. With villa holidays in Lanzarote, everyone can create lasting memories - whether that’s going underground in the Green Cave’s lava tunnels, snorkeling the coral reefs or hiking the volcanic landscapes and valleys. With adventure and natural beauty at every turn it caters for abilities and personal tastes. If you’re planning a vacation in Lanzarote and want to add a little adventure to your holiday, then we hope you’ll find plenty of reasons to get out there and get active. And with a stay in some of the best villas in Lanzarote, you’ll find the perfect home-from-home after a busy day discovering the delights on the island.This invention relates to portable lighting devices, specifically to a portable task lighting device which comprises a wheeled base having two elongated front legs that are each set into a singular unchanging position during use and two rotatable back legs that can be independently moved toward or away from one another prior to being set into a variety of fixed positions for use. The lighting device also has an upwardly telescoping mast centrally connected to the wheeled base which locks the front legs into their fixed usable positions, a pivot block connected to the top of the mast which comprises a plurality of positive locking positions, a boom arm connected to the pivot block, and an elongated fluorescent light assembly pivotally connected to the free end of the boom arm for a full 360.degree. of rotation. The combination of its telescoping mast which preferably extends between approximately thirty-two and ninety inches, its pivoting boom arm, and its rotatable light assembly allows the present invention to be placed into a nearly infinite number of configurations. It is contemplated during use for the elongated light assembly to always be positioned over the front legs for maximum stability, particularly when the telescoping mast is fully extended, and for the mast to have an asymmetrical or other cross-sectional configuration so that weight of the elongated light assembly and boom arm will not cause an unexpected rotation of any one of the extended telescoping members relative to the remainder of the telescoping mast structure. Thus the task lighting device of the present invention is stable, versatile, and adjustable into a nearly infinite number of usable positions to cast a broad, glare-free, and cool flood of light upon a targeted work surface. The present invention is also configured to be quickly and easily collapsed into a compact configuration for transport or storage by the removal of one quick-release pin from the pivot block and the loosening of several quick-release clamping devices that fix the telescoping mast members and rear legs in place during use. Applications may include, but are not limited to, indoor use for a wide variety of light-sensitive work projects that for proper completion require a direct source of shadow-free lighting.Clinicopathological study of gastric leiomyogenic tumors. 1. Seventy cases of the leiomyogenic tumors were found in 5451 resected stomachs; 49 leiomyoma, 17 leiomyosarcoma and 4 leiomyoblastoma. These leiomyogenic tumors occupied 40.5% of 173 submucosal tumors of the stomach. 2. The average age was 51.7 in leiomyoma, 57.3 in leiomyosarcoma and 41.6 in leiomyoblastoma with male predominance. 3. The leiomyoma and leimyosarcoma were frequently found in the upper 2/3 of the stomach. 4. The size of the tumors was within 3 cm in diameter in about 80% of leiomyoma with ulcer formation of 10.2% and over 3 cm in about 88% of leiomyosarcoma with ulcer formation of 64.7%. 5. The classification of the leiomyogenic tumors into the benign and malignant was occationally difficult. For the diagnosis of the leiomyosarcoma, the number of mitosis, irregularity of nucleus, increase of cellularity and decrease of smooth muscle production were helpful.Sometimes a blog must serve as a repository of regrets, a place to atone for not including some perfect fact in a book. While working on my book Parasite Rex, I came across many delicious examples of parasites manipulating the behavior of their hosts for their own benefit. After the book came out, I met scientists who enlightened me about other examples which would have been wonderful to include. A few years back, for example, a Johns Hopkins scientist pointed me to a parasitic wasp that turns cockroaches into zombies. I’ve recently been wondering about behavior-altering viruses, thanks to an online conversation I had with Ian Lipkin, a virus hunter at Columbia University, about my new book A Planet of Viruses. Lipkin wondered aloud if some viruses would turn out to manipulate their hosts for their own good. Did herpesviruses, for example, increase its transmission by boosting their host’s sexual desire? Most of the examples I knew about came from parasitic animals and fungi. The only virus that could have this kind of effect that I knew of was rabies, which causes its hosts to become more aggressive. A rabid dog that bites anything that crosses its path may be able to spread the virus more. But I suspected that there were many other puppet master viruses out there. Well, while I was at California State University Fresno last week to give a talk, I met an entomologist named Fred Schreiber. He asked me if I had ever heard of baculoviruses. They rang a bell in my head, but only faintly. So Schreiber told me an eldritch tale… Baculoviruses infect invertebrates, with each species of virus typically infecting only one species of host. Caterpillars are a particularly favorite target; the insects swallow baculoviruses sprinkled on the leaves they munch. (“How did the viruses get there?” you may ask. Very good question–which we’ll get to in good time.) Once inside the caterpillar, a baculovirus infects a host cell. The cell produces huge numbers of new baculoviruses. They come in two forms. Some of the viruses can slip out of the host cell on their own to infect new cells. Others stay in the cell, which makes huge quantities of a viral protein called polyhedrin. The viruses become embedded in massive polyhedrin blocks, like fruits in a fruitcake. A caterpillar may produce 10 million viruses from swallowing a single viral fruitcake. It even becomes visibly swollen with all its new viruses. Soon the virus-packed host gets an uncontrollable urge to creep its way to the tops of plants, where it clamps on tight, hanging down as shown in the picture above. In fact, scientists noticed these strange death throes long before they knew that baculoviruses that caused it. They dubbed it tree-top disease. After an infected caterpillar takes its position at the top of a plant, the virus releases an enzyme that literally makes the animal dissolve. The tough viral fruitcakes come tumbling out, landing on leaves below where they can infect a new host. Hearing about tree-top disease gave me a deep sense of deja vu. A number of very different parasites have evolved the same strategy for getting to new hosts. Just a couple weeks ago, for example, I blogged about a fungus that sends its ant hosts to the undersides of leaves, whereupon the fungus sprouts branches out of the ant’s head and showers spores down on new victims. Lancet flukes send their hosts up to the tips of grass blades so that they can be eaten by grazing cows and sheep. It’s fascinating that even a virus–with just a few genes–can trigger this behavior as well. Scientists have identified one of the genes in baculoviruses that is crucial for this manipulation. It causes insect hosts to start wandering in response to light. Strangely, the virus appears to have acquired this gene through a kind of evolutionary theft. The viral gene bears a striking resemblance to a gene in insects. In the insects, the gene is involved inforaging for food. It’s possible that an ancestral baculovirus picked up the host gene, which then evolved to take on a different behavior–one that sent insects to their doom, rather than to a meal. All in all, this zombie strategy is terrifically successful for baculoviruses. They are everywhere, killing insects in staggering numbers. In 1973, scientists bought heads of cabbage around Washington DC and discovered that they were coated in baculoviruses. A single serving of cabbage contained up to 100 million of them. Fortunately, baculoviruses are so finely adapted to invertebrate hosts that they pose no threat to humans. In fact, we can use baculoviruses to our advantage. Scientists can remove the polyhedrin gene from the viruses and replace it
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5657, 15, 380, 3773, 5821, 281, 1798, 4803, 323, 3879, 13, 285, 344, 13588, 1110, 4803, 15, 187, 187, 42, 452, 2326, 1142, 20121, 273, 253, 4112, 1750, 326, 2071, 40304, 2335, 2250, 1411, 2071, 5432, 348, 1947, 773, 1542, 521, 1329, 273, 253, 14025, 13591, 18162, 7521, 533, 326, 457, 84 ]	ball it would have died, and I’m equally sure I would have felt horrible as they both dropped out of the sky, but they never did. The bat would always realize, often times at the last second, that the missile was way too big to be even the most succulent moth and swoop away. It was a long time before I realized that this game must have been positively infuriating from the bat’s point of view. As incredible as this aerial display was, I didn’t really fall in love with bats until I moved to New Hampshire. I spent a summer living in the attic of a cabin in Fraconia Notch State Park, and early, early in the morning I would hear incessant squeaking coming from a corner of the ceiling. I assumed it was one of the mice I was in a constant state of battle with that summer. One evening as I was getting ready to go to bed, from the same corner I saw a bat drop out of the crack where the ceiling met the log wall. I stood frozen in the middle of that room and I could hear the fluttering sound of its wings as it flew around the room for nearly half a minute. Even in the confines of that tiny room it was an agile flyer, swooping around me, the furniture, and the walls without crashing into any of them. While I was startled by this first appearance I didn’t really mind it. Maybe I truly did miss the last train to crazy-town, but a bat seemed like short change to the plastic-chewing, food-seeking, hantavirus-carrying, no-kill-trap eluding rodents that I was currently at war with. Besides, if I couldn’t even rig a trap for a mouse, successfully evicting a bat was way out of my league. That’s when I started doing more research. Quite a few of the people I told about the bat immediately raised the concern of bats carrying rabies. As it turns out, according to the CDC, less than six percent of bats that are captured and tested carry rabies. That figure doesn’t even take into account all of the bats that are happily zipping around like tiny furry fighter pilots. There is a high percentage of human rabies cases that are caused from bats, but in many cases the patient did not seek medical attention for a trivial little bat bite. What’s more, in the majority of these cases the person was bitten while trying to remove the bat. I made a mental note to go to the doctor if I got bitten, or saw evidence that the bat was diseased and stopped worrying about it. I also was surprised to hear people say that bats made a habit of flying into people’s hair. My own observations of their ability to navigate contradicted the idea and many sources dismissed it. I hardly pay any attention to my hair anyways, and a bat stylist might have been an improvement. But I did learn something that worried me. Biologists were concerned by something called “White Nose Syndrome.” It had started with bats in New York State, and it was disrupting the bats during their winter hibernation causing them to be spotted flying around and eating snow. It was killing enormous numbers of bats, and other than a few vague references to a fungus, no one seemed to understand what was causing the bats to die. And no one knew what to do about it. I won’t say we always got along perfectly during my summer of the bats. For one thing, their habit of squeaking noisily in the ceiling at five in the morning got old fast. I also remember waking up one night to realize that a bat was noisily rustling around on top of a plastic bag that had one of my knitting projects in it. (I vaguely remember muttering “You can share my room, but stay out of my yarn!”) But more often than not I was delighted when they (literally) dropped in. I vividly remember watching one crawl around upside down using the hook-like thumb on it’s wing. I was surprised, having been told that bats need to drop from a perch to be able to fly, to see a bat crawl around on the floor in the corner of the room and then effortlessly flutter back up into flight. Besides, having a bat for a roommate earned me at least a few bragging rights. My summer in New Hampshire eventually ended. I moved back to civilization away. While I didn’t start liking bats any less, I certainly didn’t think about them as much. I still heard snippets about White Nose Syndrome here and there, and it still worried me, but I was too busy with my non-bat life to really stay in the loop. About a week ago a bomb was dropped on me. I got an email saying that Icebox Cave in Cuyahoga Valley National Park was being closed due to concerns over White Nose Syndrome. A confirmed case of White Nose Syndrome was found nearby in one of the Summit County Metroparks. I hadn’t even noticed that another case of White Nose Syndrome was confirmed in Ohio nearly a year ago. Even worse a case of White Nose Syndrome was confirmed not far from my cabin in New Hampshire the same year that I was there. The year afterwards bat populations all over the state plummeted. Even though I’m thousands of miles away in California now it’s struck a nerve. Those are my bats, in my favorite places, the ones that I used to play “dive at the softball,” with and yelled at to keep out of my stuff. I want to do something about it this time around. Although we have learned more about it, we still haven’t figured out how to stop White Nose Syndrome from killing bats. It’s caused by a cold loving fungus that probably originated in Europe. When the bats hibernate for the winter, particularly in caves and mine shafts, the fungus grows around their nose, causes lesions on their skin, and disrupts their hibernation causing them to waste precious energy stores flying around when there isn’t a food source available. White Nose Syndrome has devastated the affected bats, killing anywhere from 70 to 100 percent of their original populations. Many efforts to protect bats have been focused on preventing people from spreading the fungus. Countless parks and preserves have closed caves and mines to prevent the spores from being introduced to places where bats are known to hibernate. The Fish and Wildlife Service is encouraging cavers to decontaminate their gear before entering caves. Another way to help bats is by protecting their healthy populations. Avoid disturbing them when they are hibernating and protect the forests and wetland areas where they live and hunt. Hang bat houses to provide a place for them to live. Avoid using pesticides that kill the insects that they depend on for food. Finally, even if you can’t welcome a bat into your house, at least welcome them into your heart. As insect eaters and pollinators they play an important part in agriculture and our own food chain, not to mention mosquito control at your next barbecue. They are truly fascinating critters that are often unnoticed or feared for all the wrong reasons. They could use a little more love. You can find more information about bats and White Nose Syndrome from these wonderful places: categories Other Places You Can Find Us contact us about the content All posts are property of the author. Photos are property of the post author unless otherwise noted. Contact us with any requests for use of our content. We accept guest posts and would be happy to do the same for your blog. Just let us know!Super excited for these discs so I had to use my cruddy webcam to share them. Soft Proton Ion and a slightly used Lat 64 Bite. The Soft Proton plastic feels amazing and I have been looking for the Bite for a while now. Pup seems to like it and I got to throw these around a bit today. I'm almost sad to say I'm retiring my FLX Challenger from round play although now I'll finally have a putter pair of the same mold.▲ Brian Kibler will not be casting the Hearthstone Grandmasters finals at BlizzCon. It was only a matter of time until an influencer within the Hearthstone community would issue a public statement regarding Activision Blizzard's recent decision to ban Ng "blitzchung" Wai Chung for using his post-game interview to make a political statement calling for the liberation of Hong Kong amid political unrest out east. The first domino fell Wednesday morning when long-time caster, popular streamer, and community figure, Brian Kibler, shared a statement on his official website. Not one to shy away from speaking his mind or voicing his stances on politics, Kibler did not hold back his feelings as this one hits particularly close to home for him. Within the 788-word post, Kibler acknowledged the bravery it took for blitzchung to use his platform to issue a statement that would almost certainly put his career and personal safety in jeopardy. That being said, he understands and agrees with Blizzard handing down a punishment for his actions. "Even so, I do think that Blizzard was correct in issuing him a penalty for his actions. They do not want to set the precedent for their official broadcasts being used as political tools. The players agreed to particular rules for behavior, and he violated those rules. I have seen many descriptions of the situation claim that Blizzard took action against Blitzchung “for his support of the Hong Kong protests”, but that’s
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1383, 686, 34372, 227, 1383, 686, 162, 105, 121, 1383, 686, 162, 119, 235, 1383, 686, 164, 223, 234, 1383, 686, 164, 227, 215, 1383, 686, 164, 230, 108, 1383, 686, 165, 109, 115, 1383, 686, 35392, 120, 1383, 686, 29626, 113 ]	and extraordinary) beams cannot interfere, since the optical path difference is longer than the coherency of the light. Since the ratio of lengths is 2:1, partial beams with the same polarization plane are spaced by a common distance longer than the coherent length. Such partial beams do not interfere because of the distance longer than the coherent length, although they have the same polarization plane. A cross-term in the square of the amplitude vanishes. Thus, the square of the amplitude becomes constant for all partial beams with different polarization planes. All partial beams with different polarization planes have the same energy. This is a depolarized state. The long optical path difference eliminates interference of the beams with the same polarization planes. A single depolarizer only requires such simple conditions (BL>C, ratio=2:1). However, some difficulties will occur when two depolarizers are included in optical paths of a fiber-optic gyroscope. Will no interference between two beams which have once an optical path difference longer than the coherent length by passing through a depolarizer occur forever? Can the function for separating the optical paths of a depolarizer ensure everlasting non-interference between the once separated beams? The two beams can interfere with each other. When two beams pass through the other depolarizer, the birefringence of the second depolarizer will affect against the once-obtained separation between two beams. Sometimes the birefringence will decreases or cancel the path difference which has been endowed by the first depolarizer. In some cases, the optical path difference will become shorter than the coherent length of the light. Then, two beams will interfere! Rotation of polarization planes often occurs in a single-mode fiber, because phase constants of the beams degenerate in a single-mode fiber. If the rotation of the polarization planes occurred, the intensity of the interference beams would fluctuate, because the two once-separated beams with the same polarization planes would interfere. The fluctuation of the interference beams appears as a noise, a drift or change of the scale factors of the signals. Such a problem would appear in an gyroscope for the first time, when the Inventors introduce two depolarizers into it. Thus, the Inventors have noticed the difficulties in a twin-depolarizer gyroscope for the first time. Nobody take notice of such a problem. A purpose of this invention is to solve the problem of a twin-depolarizer gyroscope.Q: How many distinct kanjis or words are there in a typical modern Japanese book? "typical modern book " means: It's a modern book and hardly uses ancient languages or any topolects. It's something like a famous novel(not a short story) or book with a high reputation. It's a normal book, not a dictionary or technique book. Additionally, I wonder how many distinct characters can cover 99.7% of the book content. The source of the problem is that I want to know how many unstudied (the meaning of) kanjis I will meet when reading a book. A: There are currently 2136 常用漢字. However, using writers will often use 漢字 outside of this list. So I ran a script to calculate the total number of unique 漢字 in Harry Potter and the Chamber of Secrets (a modern novel mentioned there) and on ノルウェイの森/Norwegian Wood (a "famous" Japanese language novel, though perhaps not "typical") and compared it to the 常用漢字 list. You can see some of the code (it just has the results for the distinct values in the books) here. Here's what I got Harry Potter and the Chamber of Secrets: 206 non-常用漢字 out of 1768 漢字 (肱 might be a typo for 肘, 躯 for 体, 荊 for 茨, and 綴 for 絞. I also wonder if 姐 and 嬉 are old forms or my source text has typos. I also have no clue about 杵 and 磔, which are likely wrong. I'll try to confirm with a physical copy in the future.) {'蘇', '捌', '曾', '鈎', '撫', '剥', '捷', '篭', '恰', '鍮', '撒', '涎', '虱', '樽', '炸', '塵', '椀', '吼', '淀', '絢', '歪', '掠', '瞥', '揉', '眩', '董', '錆', '嘘', '楊', '蝶', '靄', '疼', '呆', '叱', '弛', '攣', '棍', '猾', '藁', '軋', '荊', '揃', '纏', '甥', '這', '樫', '苺', '掻', '惚', '杖', '煤', '咳', '煽', '辻', '瓢', '詫', '捺', '脛', '溢', '溜', '蝋', '鎧', '糞', '芻', '腿', '噛', '唸', '痺', '鍔', '霞', '狡', '翠', '昂', '罠', '燭', '蜘', '牢', '躯', '叩', '杵', '雛', '佇', '鳩', '呟', '灼', '爛', '逢', '嘴', '黴', '呑', '兎', '嘩', '濡', '轟', '鞄', '咎', '棘', '笥', '壷', '閃', '猜', '楓', '聡', '麿', '箪', '捧', '馴', '藹', '蛙', '肱', '馳', '覗', '釘', '茜', '埃', '愕', '雀', '皺', '躇', '鋸', '踝', '穣', '奢', '檻', '箒', '姐', '甜', '嵌', '萄', '螺', '嬉', '唖', '秤', '仔', '掴', '窪', '狼', '翔', '綴', '腔', '箔', '芍', '躊', '鮭', '磔', '鱗', '悶', '禿', '躓', '蛛', '惹', '閂', '哮', '瓜', '腑', '曙', '槌', '沫', '狐', '倦', '卿', '剃', '栗', '燻', '頷', '憑', '斧', '蟻', '橙', '竿', '怯', '紐', '穢', '耽', '尖', '咆', '凱', '蒼', '肋', '錘', '踵', '窩', '縞', '竪', '痙', '鞭', '吊', '喧', '聳', '髭', '焚', '廻', '斐', '堵', '頬', '醇', '瘤', '鋏', '葡', '〇', '鉤', '鷲', '漉', '舐', '滲', '堰'} ノルウェイの森/Norwegian Wood: 167 non-常用漢字 out of 1746 漢字 (Like before 姐 and 嬉 might be old forms/typos. I'll try to confirm with a physical copy in the future) {'梯', '遙', '鱸', '鎧', '梢', '徨', '撞', '喧', '昂', '雀', '而', '鳩', '庇', '轟', '燈', '葡', '拗', '函', '禿', '悶', '槌', '訊', '紐', '碗', '鞄', '鮭', '蝕', '蛙', '軋', '舐', '檻', '湘', '茗', '萄', '蓮', '鯵', '綺', '裳
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8320, 190, 187, 12676, 110, 7056, 222, 50276, 31486, 14377, 165, 120, 121, 163, 214, 101, 17492, 4888, 187, 33505, 190, 187, 361, 27, 3156, 27, 1610, 13, 8320, 6781, 7449, 27, 3156, 27, 1706, 13, 7554, 190, 187, 32004, 24370, 50276, 38242, 38242, 20622, 16401, 4888, 187, 33727, 190, 187, 361, 27, 3156, 27, 1706, 13, 14744, 6781, 7449, 27, 3156, 27, 1671, 13, 14744, 190, 187, 38242, 34439, 24446, 4888, 187, 43698 ]	17,500 我将会带着正式的命令回来进行全面调查 716 00:37:17,530 --> 00:37:18,200 我明白 717 00:37:18,400 --> 00:37:22,200 与此同时我建议您把注意力集中到人民自由联盟上 718 00:37:22,230 --> 00:37:24,200 我很清楚他们是你们的死对头 719 00:37:24,700 --> 00:37:26,100 我们将尽可能帮助你 720 00:37:26,300 --> 00:37:26,800 先生 721 00:37:27,600 --> 00:37:28,100 抱歉 722 00:37:30,600 --> 00:37:32,800 杰克的小组已经在建筑物外的集结地了 723 00:37:32,830 --> 00:37:33,600 我马上就到 724 00:37:33,900 --> 00:37:35,800 程先生抱歉 725 00:37:37,000 --> 00:37:37,900 我要回去工作了 726 00:37:38,400 --> 00:37:40,000 我的人会护送你出去 727 00:37:40,400 --> 00:37:40,900 谢谢 728 00:37:45,700 --> 00:37:46,500 埃德加 729 00:37:48,000 --> 00:37:48,600 抱歉 730 00:37:49,000 --> 00:37:51,500 埃德加斯蒂勒通信分析员是吧？ 731 00:37:51,600 --> 00:37:52,400 是的我很忙 732 00:37:52,700 --> 00:37:55,400 我忘记问布坎南先生最后一个问题了 733 00:37:55,430 --> 00:37:56,500 也许你能帮我 734 00:37:56,600 --> 00:37:57,350 我帮不了你 735 00:37:57,380 --> 00:37:58,290 你应该去问他 736 00:37:58,320 --> 00:37:59,200 不是什么机密问题 737 00:37:59,300 --> 00:38:03,800 奥德丽瑞恩斯提到说你早些时候帮助她整理国防部的文件 738 00:38:04,300 --> 00:38:05,900 是的在她被叫到医务室以前 739 00:38:06,000 --> 00:38:07,400 那么就剩你和杰克了？ 740 00:38:08,900 --> 00:38:09,600 什么？ 741 00:38:09,800 --> 00:38:10,700 埃德加过来 742 00:38:11,700 --> 00:38:12,400 我得走了 743 00:38:12,500 --> 00:38:12,800 再见 744 00:38:13,700 --> 00:38:14,000 谢谢 745 00:38:16,000 --> 00:38:16,600 你个白痴 746 00:38:16,630 --> 00:38:16,860 什么？ 747 00:38:16,900 --> 00:38:17,900 管好你的嘴 748 00:38:17,930 --> 00:38:18,900 我什么也没说 749 00:38:26,100 --> 00:38:26,500 你好 750 00:38:26,800 --> 00:38:29,000 袭击领事馆的主谋是杰克鲍尔 751 00:38:29,300 --> 00:38:30,500 调出所有他的档案 752 00:38:30,600 --> 00:38:31,300 回来我要看 753 00:38:31,400 --> 00:38:31,800 好的 754 00:38:36,100 --> 00:38:37,300 Michael 你到位了吗？ 755 00:38:37,500 --> 00:38:38,200 是的 756 00:38:38,900 --> 00:38:40,400 他在你两点钟的方位干掉他 757 00:38:40,430 --> 00:38:41,000 明白 758 00:38:54,200 --> 00:38:54,600 我们准备好了 759 00:38:55,800 --> 00:38:56,900 启动程序吧 760 00:39:13,200 --> 00:39:13,800 我们这边完成了 761 00:39:28,500 --> 00:39:29,100 去取车 762 00:40:03,700 --> 00:40:04,700 他被困在了这间屋子里 763 00:40:05,000 --> 00:40:06,400 从两面包抄把他往我这边赶 764 00:40:06,500 --> 00:40:07,000 明白 765 00:40:22,100 --> 00:40:22,800 不许动 766 00:40:26,100 --> 00:40:27,300 我一直在等着这个时刻的来临 767 00:40:29,300 --> 00:40:30,100 你太晚了 768 00:40:43,800 --> 00:40:44,900 很疼是吧？ 769 00:40:53,700 --> 00:40:54,300 杰克 770 00:40:55,100 --> 00:40:56,000 杰克你在干什么？ 771 00:40:56,700 --> 00:40:57,500 我们还能用得着他 772 00:41:04,200 --> 00:41:04,900 来吧 773 00:41:05,900 --> 00:41:06,800 杀了我 774 00:41:09,000 --> 00:41:10,300 也不会阻止导弹发射 775 00:41:12,000 --> 00:41:13,000 你在说什么？ 776 00:41:18,000 --> 00:41:19,700 你在说什么！？ 777 00:41:30,700 --> 00:41:32,400 杰克我们有麻烦了 778 00:41:33,400 --> 00:41:34,300 过来看看这个 779 00:41:34,700 --> 00:41:35,700 看好他 780
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11236, 35, 10, 6244, 6019, 329, 15, 9233 ]	Rbs1* in the spl11 plants was also confirmed in the IR64 background ([Figure S4C](#pone.0087258.s004){ref-type="supplementary-material"}). ![Gene expression and protein accumulation patterns of Rbs1, Spin1 and Spl11 inthe Rbs1 and Spin1 overexpression plants.\ A. Q-PCR analysis of the expression pattern of Spin1 and Spl11 in the Rbs1 overexpression plants under LD and SD conditions. B. Expression of Rbs1 in the Spin1 overexpression and RNAi plants. C. Western blot detection of RBS1 and SPIN1 proteins in the Spin1 overexpression and RNAi plants. RBS1 was detected using a native antibody. The SPIN1-TAP fusion protein was detected in the Spin1-OX plants using the PAP antibody. D. Western blot detection of RBS1 and SPIN1 proteins in the Rbs1 overexpression lines; RBS1 and SPIN1 native antibodies were used in the immunoblot detection.](pone.0087258.g006){#pone-0087258-g006} Furthermore, we determined the protein levels of RBS1 and SPIN1 in the Rbs1 and Spin1 overexpression plants using anti-RBS1 and anti-SPIN1 antibodies. Western blot analysis showed that enhanced accumulation of the RBS1 protein was detected in the Spin1 overexpression plants ([Figure 6C](#pone-0087258-g006){ref-type="fig"}) and that the accumulation of the SPIN1 protein was higher in the Rbs1 overexpression plants ([Figure 6D](#pone-0087258-g006){ref-type="fig"}). We also detected that the RBS1 protein level was increased in the spl11 mutant ([Figure S4D](#pone.0087258.s004){ref-type="supplementary-material"}), which is consistent with the expression data mentioned above. These results suggest that there is a positive relationship between RBS1 and SPIN1 but a negative relationship between SPL11 and RBS1. Discussion {#s4} ========== We identified RBS1 as a novel RNA binding protein of the hnRNP-R type in rice and showed that it interacts with SPIN1 in both yeast and rice protoplasts. To assess the functional relationship between Rbs1 and Spin1 in flowering time regulation in rice, we identified an Rbs1 T-DNA insertion mutant and generated both overexpression and artificial microRNA transgenic plants of the Rbs1 gene. Similar to the T-DNA mutant and the Spin1 RNAi plants [@pone.0087258-VegaSnchez1], the Rbs1 artificial microRNA plants did not show any difference in flowering time compared with the wild type plants in both LD and SD conditions (Data not shown). However, like the Spin1 overexpression plants [@pone.0087258-VegaSnchez1], the Rbs1 overexpression plants show late flowering under SD and LD conditions. Expression analysis showed that Rbs1 overexpression leads to the suppression of both Hd3a, the rice florigen [@pone.0087258-Tamaki1]. Our results clearly demonstrate that RBS1 is a flowering suppressor that interacts with SPIN1, and this interaction could lead to regulate the expression of flowering genes in rice. Genome analysis showed that there are 196 RRM-containing proteins in Arabidopsis and 221 proteins in rice [@pone.0087258-Lorkovi1], [@pone.0087258-Morris1]. In rice, LOC\_Os10g06130 also encodes an RRM-containing protein, which has 88% protein sequence similarity with RBS1. The expression of this gene is not affected in the Rbs1 overexpression and artificial microRNA plants (data not shown). This gene may have redundantfunction with Rbs1 in rice flowering, which might explain our observationthat the rbs1 knockout mutant and artificial microRNA plants did not show any significant flowering time change under SD and LD conditions. In the Rbs1 overexpression plants, the expression of Spin1 is upregulated, which correlates with enhanced SPIN1 protein accumulation. We have previously shown that the Spin1 overexpression plants flower later than the wild type Nipponbare plants under SD and LD conditions [@pone.0087258-VegaSnchez1]. In SD conditions, the expression of Hd1 is reduced in the Spin1 overexpression plants, indicating that SPIN1 influences flowering time via the Hd1 pathway in flowering-promoting conditions. However, in LD conditions, the Hd1 expression, is the same in Nipponbare and Spin1 overexpression plants [@pone.0087258-VegaSnchez1], suggesting that SPIN1 may target an unknown factor to regulate Hd3a under LD conditions. By contrast, in this study we found that the expression of Hd1 is similar between the Rbs1 overexpression and wild type Nipponbare plants under both LD and SD conditions ([Figure 5C](#pone-0087258-g005){ref-type="fig"}). Interestingly, in the Rbs1 overexpression plants, the mRNA level of Hd3a is suppressed under both SD and LD conditions. These data suggest that RBS1 may function to regulate flowering in rice via the suppression of Hd3a-mediated mechanisms. Our previous study revealed the negative relationship between SPIN1 and SPL11 [@pone.0087258-VegaSnchez1]. In this study, we also found that the expression of Spl11 is repressed in the Rbs1 overexpression plants. In contrast, both the expression of Rbs1 and accumulation of the RBS1 protein are increased significantly in the spl11 mutant, indicating a negative relationship between RBS1 and SPL11. However, the direct relationship between these two proteins remains unclear. Yeast-two hybrid assays using SPL11 as the bait and RBS1 as the prey or vice versa did not detect any interaction between them (Vega-Sanchez and Wang, unpublished results). It is plausible that RBS1 is one of the components in the SPL11 protein complex and the interaction between RBS1 and SPL11 requires the presence of another protein that interacts with both proteins, for example SPIN1. Because RBS1 is a putative RNA binding protein and has RNA binding activity in vitro, it might be involved in RNA metabolism to regulate flowering time. In mammals, it has been recently shown that hnRNP-R binds to the 3′UTR of serotonin N-acetyltranferase and to the AU rich element of c-Fos mRNA to promote their degradation [@pone.0087258-Kim1], [@pone.0087258-Huang1]. Whether Rbs1 is involved in mRNA turnover in rice needs to be determined in future studies. It is interesting to note that the putative ortholog of RBS1 in Arabidopsis, LIF2, is also involved in flowering time control [@pone.0087258-Latrasse1]. However, at this point, it is unclear whether LIF2 and RBS1 are functional homologs. LIF2 seems to be part of protein complex that regulates gene expression via epigenetic mechanisms [@pone.0087258-Latrasse1]. Whether RBS1 acts similarly to regulate flowering and other developmental pathways needs to be explored. Complementation studies of the Arabidopsis lif2 loss-of-function mutants with the rice Rbs1 gene should provide clues as to whether these pathways are conserved or not between the two species. Supporting Information {#s5} ====================== ###### Identification of *Rbs1* by yeast two-hybrid screen in a rice cDNA library using the full length *Spin1* as the bait. Numbers 72 and 69-2 are independent yeast clones containing the pDBleu-Spin1 and pPC86-Rbs1 constructs. Positive clones were identified by an X-GAL assay. (TIFF) ###### Click here for additional data file. ###### Molecular analysis and flowering time of the *rbs1* mutant. A. Structure of the T-DNA insertion. T-DNA was inserted into the fourth intron of Rbs1. Arrows indicate the primers used for analyzing the insertion site. LB and RB represent the left and right borders of T-DNA; B. PCR genotyping of the rbs1 mutant. DJ denotes Dongjin, 1 is a segregated wild type, 2 and 3 are homozygous plants and 4 is a heterozygous plant; C. Expression of Rbs1 for the plants in S3B; D. Flowering time of the rbs1 mutant under LD and SD conditions. (TIFF) ###### Click here for additional data file. ###### Western blot analysis of the protein level of RBS1 in the *Rbs1* overexpression and wild type plants. (TIFF) ###### Click here for additional data file. ###### Expression analysis of *Rbs1* in the *Spin1* overexpression plants, *spl11* mutant plants and wild type Nipponbare (NPB) plants. A. RT
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13416, 13, 4232, 247, 2169, 7759, 13521, 323, 2120, 14, 6851, 14, 12080, 272, 5213, 3484, 13, 534, 8058, 5547, 15, 187, 187, 3039, 747, 2143, 14, 3169, 6938, 24040, 497, 4081, 275, 10226, 1293, 3806, 281, 643, 6110, 4676, 13, 309, 9521, 253, 19172, 273, 8404, 13416, 281, 3812, 2366, 512, 4676, 281, 2319, 14149, 3237, 323, 5689, 49, 285, 7956, 15286, 285, 643, 2831, 14, 19221, 2561, 23221, 13, 15806, 27, 187, 187, 1051, 247, 1895, 18964, 253, 5286, 285, 8362, 23240, 6319, 942, 326, 16027, 5705, 313, 12722, 7070, 1100, 10, 285, 23221, 281, 2173, 27498, 273, 12602, 15, 3900, 841, 16669, 4176, 2143, 14, 6160, 5705, 13, 285, 734, 36078, 789, 4518, 1561, 581, 2143, 13, 597, 513, 417, 5752, 973, 734, 14, 19221, 24040, 13, 824, 347, 7956, 15286, 13, 9947, 947, 13, 285, 30182, 51, 3346, 187, 187, 688, 629, 347, 247, 2380, 281, 9437, 387, 25846, 13454, 7956, 15286, 4712, 13, 309, 9262, 247, 7000, 40456, 9224, 281, 253, 7956, 15286, 11354, 7039, 13, 1690, 8332, 323, 247, 19897, 9966, 15, 7850, 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281, 2489, 3907, 273, 667, 2143, 275, 1091, 323, 534, 253, 9145, 651, 2489, 4751, 1881, 14, 34492, 285, 5454, 762, 247, 747, 1416, 15, 2896, 253, 807, 6585, 13, 253, 5625, 11841, 15836, 6516, 313, 2431, 7142, 10, 574, 8228, 281, 2145, 3576, 2120, 14, 2606, 4750, 14597, 37372, 1108, 1690, 323, 253, 9966, 285, 19897, 15, 496, 253, 22849, 13, 752, 4592, 281, 253, 6938, 9551, 13521, 32, 187, 187, 1835, 577, 15, 46484, 338, 3328, 273, 6938, 24040, 187, 187, 3463, 253, 2393, 7901, 84, 13, 247, 1180, 273, 20036, 275, 380, 2499, 273, 23224, 1479, 4611, 574, 1600, 275, 253, 686, 20034, 1383, 253, 3159, 1024, 15773, 275, 2282, 14505, 273, 387, 1878, 4314, 20036, 2439, 1740, 6629, 15, 1623, 581, 1133, 13, 436, 369, 2326, 347, 271, 3629, 1180, 273, 4750, 26182, 686, 20034, 8, 347, 271, 1774, 32873, 4468, 15, 1623, 253, 643, 1133, 13, 352, 369, 2326, 347, 22802, 327, 253, 686, 20034, 267, 3961, 88, 5154, 8, 275, 1340, 281, 1756, 2143, 285, 7811, 267, 47132, 942, 285, 7624, 8362, 15, 733, 369, 2779, 690, 273, 1016, 15, 187, 187, 8457, 253, 5689, 49, 13521, 369, 12691, 275, 1264, 6629, 273, 1263, 13, 352, 4455, 417, 594, 7011, 347, 281, 320, 1527, 281, 2983, 407, 5899, 6284, 15, 1723, 13, 253, 12296, 369, 10693, 6079, 327, 253, 7956, 15286, 9224, 672, 760, 767, 2607, 846, 352, 369, 7012, 407, 253, 2499, 6456, 13, 40140, 3053, 323, 12085, 6938, 24040, 15, 831, 310, 417, 281, 1333, 627, 369, 642, 2316, 323, 686, 30991, 800, 8 ]	); peatlands (Hamilton and Hodder, 1978); interagency planning for energy resources (Fookes and Hutchinson, 1978); critique of report on Pureora forest plans (Fookes, 1978); environmental perception and planning (Ericksen, 1978); biological assessment of water quality (Hamilton, 1979); the aluminium debate (Ericksen, 1980); NZ lowland forests (Thompson, 1980); managing hazardous wastes (Penny, 1985); new environmental administration (Dixon and Gunn, 1986); and Ecopolitics III (Dixon, Gunn and Ericksen, 1988). ESU published the conference proceedings. ###### Environmental news Foundation ESU Executive member Keith Thompson (Biological Sciences) proposed in 1978 to establish a periodical titled Environmental News, which he would edit and publish. Between 1978 and 1984 there were 10 issues averaging seven items per issue all germane to environmental issues of the day (CEARS Proposal, 1989, Appendix 3, Environmental News, p2). ##### Resourcing ESU activities Clearly, Tom had helped spawn not only a very productive ESU, but also ideas for its continued development and success. Activities of ESU Executive members were, however, carried out over and above their required duties within respective departments and schools of study. There was no concession in workloads from departmental heads and every expectation that ESU members would research and publish in support of their departments. Fortunately, departments from which the ESU Executive Secretary was drawn supported secretarial functions and materials. Biological Sciences supported production of Environmental News edited by one of its staff, while Geography and Earth Sciences helped produce the wide range of documentation. Having conceded there was a resource need, the Vice-Chancellor provided a very small running grant ($350) in 1977. In trying to overcome the wider resource problem, ESU Executive members proposed in 1978 establishing an Environmental Studies Centre (ESC) (Fookes et al, 1978), hoping a stand-alone centre might attract internal and external funding. It failed to gain University support. In 1981, the unpaid part-time Director of ESU (Dr Gordon Edgar) made a formal approach to the Committee of Vice-Chancellor and Deans for funding of ESU activities and the running grant was increased to $1,200. To this point, the only external funds for ESU-supported activities had come for the Huntly Monitoring Project from 1975 to 1981, three Fulbright Fellows involved in teaching and community outreach (1977–1979), and some central and local government support for the Research Fellow directing FORLD in 1980. Thereon, ESU public outreach was carried voluntarily by ESU members. This piecemeal approach to resourcing its activities needed to change. By 1979, Council had formally recognized ESU, and as the Executive Officer, Tom Fookes had written its First Report to Council. He outlined the past history of ESU and its impressive achievements in the three years to 1979, much of it through voluntary staff contributions outside their disciplines. His report included the concern of ESU Executive members that 'no decision had been made on staffing and resourcing requirements to enable the Unit to continue to function' and concerns about 'a decision on who will teach Contemporary Environmental Issues in 1980'. This was followed by another report titled Request for Urgent Review of the Future of the Environmental Studies Unit. It highlighted the dimensions of the problem facing ESU and put forward several options, including: either implementing the Quinquennial Submission (Fookes et al, 1978); or inviting applications from senior staff to be Acting Director of the Unit's affairs. As it happened, ESU was rescued for the time being by the mostly externally funded FORLD research project in 1980. Thereon, the voluntary work of ESU Executive members continued, including developing the REP teaching programme. Nevertheless, to help relieve the pressure of voluntary contributions and to advance the cause of interdisciplinary environmental research, the ESU Executive in 1989 once again proposed establishing of a stand-alone centre with capacity to compete for external funds. Meanwhile, Tom Fookes had left The University of Waikato in 1983 to be an environmental assessment officer in the South Australian Department of Environment and Planning. In 1987, he became a senior policy analyst in the new Ministry for the Environment (MfE) in Wellington. The latter enabled him to reconnect with his former colleagues at The University of Waikato, especially where their projects drew on MfE information and support. #### 3. Centre for Environmental and Resource Studies Some 10 years after ESU's proposal for an Environmental Studies Centre (ESC), members put forward a new proposal. The Centre for Environmental and Resource Studies (CEARS) differed markedly from its predecessor, reflecting the evolving nature of the broad field of study from emphasis on resource development in the 1960s to emphasis on environmental quality in the 1970s, to emphasis on a balanced approach to resource development and environmental quality from an interdisciplinary perspective (CEARS Proposal, 1989, Appendix 4, Previous ESU Proposals for a Centre, pp21–22). With support of the departments contributing to the REP teaching programme, a proposal for CEARS was prepared by me as ESU Secretary.2 The CEARS business plan was adopted by the University Council on 23 August 1989, but the Vice-Chancellor held firm to his view that CEARS be administratively located within a school. He invited me, a geographer, to be founding director of CEARS. As Geography was within the School of Social Sciences, administrative responsibility for CEARS came under the Dean of Social Sciences, with physical location in the Department of Geography. This would soon cause problems for the REP multidisciplinary programme, as explained later in section 4. In many respects, CEARS took over the functions and aims of ESU, but with the added aim to 'Develop research proposals for contracts with outside agencies so that CEARS moved towards being a financially self-sustaining venture within the university' (CEARS Proposal, 1989, p7; Calendar, 1991, p385). For the first year in 1990, both CEARS Director and Secretary were half-time. A large CEARS Management Committee involved senior staff from all interested departments, in effect cutting out former ESU members. Even though the CEARS Plan had its Director as co-ordinator of the REP programme and teaching in it, the three schools supporting REP were unwilling to provide a modest grant of $15,000 each to support this activity. Indeed, not only was the CEARS Director soon instructed not to be the overall co-ordinator of REP, but also that CEARS was not to enrol postgraduate New Zealand students to engage in its research projects. To overcome this loss of a potential income stream, CEARS, at the suggestion of the Dean of Social Sciences, established a higher degrees programme for full-fee-paying international students, which proved successful. When new school-based environmental programmes were proposed in 1991 without reference to other interested parties, I requested the Dean of Social Sciences to draw together all parties to discuss emerging problems for REP and CEARS and other cross-school research centres, noting: ... a problem reflecting the administration and funding arrangements that ties subjects (disciplines) and centres to specific Schools of Study. While these arrangements suit school-specific subjects, and interdisciplinary work clearly within one school, they do not serve well inter-school programmes, such as CEARS, SMER, and CMSR... In part as a response to attempts at curtailing CEARS activities, I submitted a detailed Strategic Plan to the CEARS Management Committee, including provision for a Deputy Director. Its main thrust was for externally funded research (and a smaller and more relevant management committee). Filling the role, Dr Richard Warrick brought with him an internationally funded three-year contract on policy options for Bangladesh under a changing climate. So commenced a fruitful stream of international and national contracts for environmental research and training, including two long-running FRST-funded proposals on climate change (CLIMPACTS) and planning under co-operative mandates (PUCM). In 1996, a new dean sought to not only claw back the Director's salary (which stemmed from my having been in Geography), but also dramatically increase overheads on CEARS contracts. This was a monumental impediment to successful pursuit of our higher degrees programme and interdisciplinary research and training. In response, a proposal was put to the new Vice-Chancellor (Bryan Gould) for CEARS to become independent of any school in return for which the centre would become fully self-funded and trade under a new name. By the year 2001, the International Global Change Institute (IGCI) had grown to 13 effective full-time staff funded externally – including for the Director and Deputy. In the meantime, what happened to the environmental teaching programme? #### 4. Proliferation of environmental programmes By the early 1990s, a number of departments in The University of Waikato had interest in the 'environment', the word now featuring in course titles of at least eight departments across four schools. On one hand, this was seen as an increasing number of staff recognizing 'environment' as an important disciplinary concern. On the other hand, it was seen as jumping on the 'environmental bandwagon' in order to grow school and departmental enrolments and thereby funding. It was likely some of each. Because the REP programme was embedded in three schools of study, it seemed not so isolated as to be open to attack by traditional interests. However, the ink was hardly dry on the CEARS Plan when only two months after it was approved by the University Council, lobbying started for competitive environmental programmes. This is not to say there was no room for 'alternative'
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3395, 1929, 347, 247, 259, 4524, 11258, 13, 24663, 36621, 342, 15423, 6400, 5350, 285, 247, 8386, 313, 13712, 3984, 323, 19083, 3885, 10, 15653, 3039, 253, 5654, 11226, 13, 703, 816, 40248, 562, 751, 247, 4023, 273, 6616, 937, 31562, 21661, 8406, 25635, 27301, 1648, 13, 665, 6337, 1411, 401, 15100, 9516, 275, 1029, 2143, 16382, 275 ]	only text height, not the whole image. * IE8: * This method is only partially supported. Only one rectangle is returned which begins at the top left corner for the first selected row, and ends at the bottom right corner of the last selected row. * There is known bug when text is wrapping to next line returned rect doesn't match selection [#1895](https://github.com/ckeditor/ckeditor4/issues/1895). HIV progression at a standstill Although most people that get infected with HIV develop AIDS, rare individuals maintain immune function in the presence of virus, a phenomenon also seen in natural hosts of the closely related SIV. Muenchhoff et al. describe a cohort of pediatric HIV patients who have normal CD4 T cell counts, despite high viremia and lack of antiviral treatment. These children have low immune activation, including less chemokine receptor CCR5 expression on central memory CD4 T cells, similar to sooty mangabeys infected with SIV. The immune mechanisms described in these patients shed light on HIV pathogenesis, which may help develop future treatments.Olympian Suzy Favor Hamilton was one of the country's greatest runners—she was also a high-priced call-girl. Why would a woman with so much to lose choose to play that game? Curled into the corner of a plush sofa in the lobby of a hotel in Chippewa Falls, Wisconsin, three-time Olympian Suzy Favor Hamilton was fielding questions from the starstruck president of the local all-ages track club before taking the stage as the honorary guest at the group's February 2012 awards banquet. One of America's fastest-ever female middle-distance runners, and a representative for Reebok and Nike at the pinnacle of her career, Favor Hamilton is beloved here in her home state as much for her readiness over the past quarter century to pop up cheering at charity runs and promote locally produced soy sauce and green beans as she is for her athletic prowess. Dressed for the event in an elegant black sweater and knee-high black boots—her slightly sidelong, wry grin dazzling as ever—she gamely ticked off her career highlights for the club's president, Wade Zwiener: winning 11 Wisconsin state high school titles; snagging an unprecedented nine NCAA titles at the University of Wisconsin, and, of course, making it to the Olympics—"something I'd trained for since I was a little girl." More From ELLE Since her retirement from professional competition in 2006 at 37—with a body "almost like an 80-year-old, from all the running I've done," as she's said—she's been running three to five miles five days a week, she told Zwiener, which is the sweet spot that "seems to keep me injury-free." She's been open in recent years about her use of Zoloft and therapy to combat depression, but on this night she was effusive about her sport's mental-health benefits, calling running "the magic drug for me my entire life." And she was funny, putting her finger to her chin, Diane Sawyer–style, at one point to purr (as well as a woman with a strong heartland twang can), "What do you think running brings, Wade? Let's turn the tables." Zwiener giggled: "No, I totally agree with you—[it helps with] the mood-type stuff. And it helps keep the beer gut off middle-aged guys like me." Wrapping up, Zwiener expressed humble thanks: "I just thought, Ya know, when am I going to get the chance to talk to Suzy Favor Hamilton? It's awesome!" And with that, Favor Hamilton jumped up, spun Zwiener around in his seat to face his buddy standing by with a camera, and bent down to give him a big kiss on the cheek. "Did we get that?" she said, laughing, to the camera guy. "Oh, jeez," said Zwiener, adjusting his glasses and blushing. "I'm going to frame that one. I mean, jeez!" Favor Hamilton's flirty buss, while charming, seemed oddly prefeminist, in the fashion of a 1950s starlet dishin' out a dash of sauce—except perhaps when she gushed to Zwiener about recently having won the Rock 'n' Roll "stiletto race" in Vegas: "In my bra, too!…They were like, 'She is a go-getter!'…If you google the stiletto race, you'll get to see parts of it." Looking back a year later, however, the truly surreal moment of the encounter came when Zwiener asked Favor Hamilton what she'd been up to lately. "A lot," she replied, nodding wide-eyed. As much of the world now knows, in addition to selling real estate and raising a daughter, now seven, with her husband, Favor Hamilton at the time was working as a $600-per-hour call girl, scheduling dates in Las Vegas, Chicago, Los Angeles, and elsewhere. When a reporter for The Smoking Gun—presumably tipped off by one of her clients—confronted Favor Hamilton in the lobby of a Las Vegas hotel early last December, she initially denied involvement with Haley Heston's Private Collection, billed on its now dismantled website as "the premier Boutique Escort Agency of Las Vegas." Yet when the reporter showed Favor Hamilton, who used the curiously midwestern white-bread alias Kelly Lundy, evidence to the contrary, likely from the escort agency's tweets, the once mighty athlete crumpled. She said her husband, Mark Hamilton, a former University of Wisconsin baseball player whom she met her freshman year of college and married a week after graduation, knew about her work but didn't approve. And she never thought she'd get caught, she said, because, well, Tiger Woods, "the biggest athlete ever, obviously thought he could never get caught." The Smoking Gun story broke on December 20. Later the same day, Favor Hamilton released a series of Twitter posts explaining that she'd been drawn to escorting "because it provided many coping mechanisms for me when I was going through a very challenging time with my marriage and my life." In her carefully worded mea culpa (wisely, she skipped the Tiger Woods comparison here), she wrote: "I do not expect people to understand. But the reasons for doing this made sense to me at the time and were very much related to depression." The news of Favor Hamilton's double life—in the escort promo pictures that raced across the Internet, "Kelly" was shown crouching in stilettos or standing on a bed in a black bikini, her face always strategically concealed—prompted predictable commentary about the lamentable state of modern marriage, as well as equally predictable briefs in defense of prostitution as sex among consenting adults. The exposé also inspired a bumper crop of lewd jokes and who knows how many idle fantasies (three married women I know had dreams about flying to meet strange men for sex after hearing of Favor Hamilton's exploits). Then came the press releases: Disney, Foot Locker, and the Rock 'n' Roll Marathon Series quickly dropped Favor Hamilton as an endorser. Even the Wisconsin Potato & Vegetable Growers Association no longer wished to have the tarnished athlete beaming over a bowl of spuds in its ads. While Favor Hamilton has obviously struggled with depression—this wasn't the first time she'd spoken publicly about it—what she did remains astonishing to many. She was, after all, a much-admired woman with a young daughter, a lovely home in Madison, and flourishing real estate and motivational-speaking businesses. How could she do something so risky for herself and her family? (The Las Vegas police are not investigating Favor Hamilton, according to a department spokesman, though she could still be vulnerable to federal prosecution for sex trafficking across state lines.) Yet with every fresh tale of an athlete flaming out spectacularly—and, lately, with Manti Te'o, Oscar Pistorius, Lance Armstrong, and, yes, Suzy making headlines, there have been a slew of them—we're forced to acknowledge that the same qualities that make elite athletes great may also contribute to their downfall. Advertisement - Continue Reading Below Favor Hamilton's path as a runner began with a simple, joyful insight she had as a girl. Growing up in Stevens Point, Wisconsin, she loved to play on a string of wooded trails beside the banks of the Plover River, racing to collect branches to build forts with her older brother and two older sisters. "Pretty soon I'd be galloping," she once said. "I remember that it felt so easy, running like that for hours. I actually pretended that I was a horse." With coaching from her father, Suzy ran her first big race, a 400 meter, in fifth grade. She shot past all the girls, then all the boys. And blazing into the finish, she heard spectators shouting "Su-zy! Su-zy! Su-zy!" That was the moment, she's said, that got her hooked. Reaping more medals than any other Wisconsin runner (again, boy or girl) while in high school, she became known as a wunderkind, genetically gifted with extraordinary lung capacity and a kick (track speak for finishing speed).""When the gun fired, she just sprang out like a ball of muscle," recalls Madison writer Ruth Conniff, who ran against Favor Hamilton in high school meets in
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D. Bordeaux, 1929), is located on the northwest corner of Isabella and Main. ISETTA: Italian motorcycle designer Renzo Rivolta of Iso Rivolta began manufacturing this tiny vehicle in 1952. Meaning "Little Iso" this car was truth in advertising as it measured only 90" by 54" and had a top speed of 53 MPH. BMW obtained a license to manufacture them in Germany and produced 160,000 between 1955 and 1962. (See Corvette.) 14 » ISETTA: They really were small ISOLDE: Named for the heroine of a medieval love story, Isolde the Fair is the lover of Sir Tristram. Following an estrangement, Tristram is wounded in battle. He sends for Isolde but dies of despair when he believes she is not coming. Of course Isolde arrives, finds Tristram dead and dies of a broken heart. IVANHOE: He is a knight in Sir Walter Scott's romantic novel of the same name set in 12th century England. IWO JIMA: This is a volcanic island in the western Pacific Ocean. During WW II there was a large Japanese air base here. The battle was one of the bloodiest of the Pacific campaign. The United States Marine Corps captured the island following a two-month (February-March, 1945) siege. Five marines placed an American flag on its highest point, Mount Suribachi, following the victory. Photographer Joe Rosenthal captured the moment on film. This Pulitzer Prize winning photograph is one of the most famous images of the War. ### "BOULEVARD OF HUNDREDS OF BENEFITS" During the 1990s as Houston's Asian population increased dramatically, City Council voted to allow street signs in Chinese and Vietnamese to be placed on poles underneath the street's English name. (For unknown reasons a 2001 proposal to allow Koreatown to do the same was denied.) The purpose was to assist this influx of immigrants to find their way around. The rule was the Asian word had to be close to either the meaning of the existing street name or phonetically sound like the English street. So if you are driving in Chinatown or Little Saigon look for these signs: Bellaire – _Bai Li_ – Boulevard of Hundreds of Benefits Harwin – _Hao Yun_ – Good Luck Clarewood – _Wu De_ – Martial Arts Wilcrest – _Wei Dao_ – Traditional Moral Principles Milam – _Nguyen Hue_ – Vietnamese king symbolizing patriotism West Gray – _Hai Ba Trung_ – Vietnamese queens, Trung sisters, who defeated the Chinese in the 1st century A. D. Anita – _An Loc_ – Battlefield site during Viet Nam War Elgin – _Yen Do_ – Academic Excellence Holman – _Hung Vuong_ – First King of Viet Nam Travis – _Tu Do_ – Freedom ## J J. B. LEFEVRE: He held the positions of City Manager and Finance Director of Baytown. ** J. R. TOWLES: Justin Richard Towles was born in Crosby, Texas, a small community east of Lake Houston. A talented baseball player he was drafted by the Houston Astros in 2004. He worked his was up through the Houston farm system and made his major league debut as a catcher on September 5, 2007. Fifteen days later he chalked up 8 runs batted in, a new Astro record. The street, Sunnyview Way, that ran in front of his childhood home, was renamed in his honor in 2007. JACINTOPORT: At the end of this street is a 62-acre terminal facility fronting on the Houston Ship Channel and operating under the Port of Houston Authority. It is a cargo handling and stevedoring firm. JACK JOHNSON: Arthur John "Jack" Johnson was the best heavyweight boxer of his generation and the first black heavyweight champion. His record was 73-13-9-9 (wins, losses, draws and no decisions). Born in Galveston in 1878, he entered the ring as a young man and by 1902 had won 50 fights. He won the heavyweight belt in 1908, knocking out Tommy Burns, a white man, in a 14 round fight in Australia. To say the least this did not sit well with the white population in the pre-civil rights era. Like many athletes today his flamboyant lifestyle got him in trouble with the law. In his case, violating the Mann Act (transporting women across state lines for immoral purposed). He served a prison term for this. Johnson lost his title in a bout with white challenger, Jess Willard, in 1915. He was killed in a car wreck in 1946. JACK LONDON: He was an American who wrote novels and short stories whose main theme was the 1849 Yukon gold rush. His real name was John Griffith. Among his greatest and most readable works are _Call of the Wild_ and _White Fang_. JACK: Baytown developer W. E Defee named three streets for his children: Jack, James and Murrill. (See Defee.) 5 JACKSON BAYOU: This street and the 3.5 mile watercourse that meanders through Crosby, Texas are named for Humphrey Jackson. An Irish lawyer, he came to America in 1808 and settled on a sugar plantation in Louisiana. He fought at the Battle of New Orleans. Jackson moved to Texas in 1823 to join Stephen F. Austin's colony. Because of his legal background he became active in local government. He was killed by a falling tree while clearing his land in 1833. , JACKSON: Abner – This Virginian and his business partner, James Hamilton, a former governor of Virginia, came to Texas in 1838 after suffering some business reversals in their home state. In 1844 the partners started Retrieve Plantation in Brazoria County. Jackson built Darrington Plantation nearby and founded the town of Lake Jackson. Things were going well until the War Between the States brought disaster to the plantation economy. He died in 1861 a broken man. » JACKSON: Abner Jackson Plantation House JACKSON: This is one of several area streets we have named for a U.S. President. Andrew Jackson was the 7th American to hold the nation's highest office. JACKSON: This road is named for another lumber town in Montgomery County that faded away as the timber industry diminished in that area. Located on the Chicago, Rock Island & Pacific Railroad, Jackson received a post office in 1910 but saw it closed 15 years later. By 1946 it was a ghost town. JAMES BOWIE: Jim Bowie is revered by Texans for his heroic death at the Battle of the Alamo on March 6, 1836. He is eulogized by the Kingston Trio in their moving 1959 rendition of Texan Jane Bower's song _Remember the Alamo:_ "Jim Bowie lay dying but his powder was ready and dry/Flat on his back Bowie killed him a few in reply." He is also remembered for his invention of the famous Bowie Knife. When he first arrived in Texas he searched futilely for lost treasure near the San Saba River, seeking what is known today as the Lost Bowie Mine. JAMES: (See Jack. ) JANE LONG: She is known as the "Mother of Texas" because she bore the first child of Anglo descent on Texas soil. Long was also a member of Stephen F. Austin's Old Three Hundred. JARDIN: One of developer Edward Crain's favorite places in the world was the Tuileries Gardens in Paris, France. They are probably the finest existing example of formal French gardens. Landscape architect Andre Le Notre designed them in the 1600s as part of the grounds of a palace for Catherine de Medici. Crain used the French word for garden to name this Southside Place street to remind him of this beautiful place. JARRARD: Ed J. – This gentleman was a real estate developer in West University Place in the 1920s. His partner was Preston R. Plumb. (See Plumb.) 14 JEAN LAFITTE:** Called everything from a bloody buccaneer to a gentleman privateer, Lafitte is one of Texas' more colorful characters. In fact no one knew the truth about the man called the "Prince of Pirates." His early life is a mystery but we do know he led a group of smugglers stationed at his stronghold in Barataria, south of New Orleans, from 1810 until 1814. In 1814 he and his men joined with General Andrew Jackson to defeat the British army at the Battle of New Orleans, allowing the Americans to win the War of 1812. For his valorous actions President James Madison pardoned him and his sailors of all crimes they had been accused of committing. In 1817 Lafitte moved his operations to Galveston Island. Unfortunately, some of his subordinates attacked American ships and the government put a price on his head. Not wanting a confrontation with the U.
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16, 11717, 14, 39629, 15, 1763, 28, 187, 187, 283, 25902, 64, 30289, 723, 187, 12233, 2829, 604, 4961, 246, 18, 28, 187, 12233, 5199, 604, 4961, 268, 18, 28, 187, 283, 14760, 64, 30289, 723, 187, 6953, 2829, 246, 18, 313, 66, 38021, 9, 10637, 10, 1894, 873, 41996, 261, 558, 187, 6953, 5199, 268, 18, 313, 249, 247, 38021, 9, 10637, 10, 1894, 873, 41996, 261, 10, 5669, 715, 246, 18, 2193, 313, 66, 558, 187, 187, 10452, 427, 37743, 8985, 28, 187, 24434, 268, 18, 12196, 1253, 3353, 5137, 187, 7135, 346, 1532, 327, 6303, 8915, 3664 ]	.hops.hopsworks.util.Helpers; import io.hops.hopsworks.util.JavascriptExec; import io.hops.hopsworks.util.models.User; import org.openqa.selenium.By; import org.openqa.selenium.NoSuchElementException; import org.openqa.selenium.WebDriver; import org.openqa.selenium.WebElement; import org.openqa.selenium.support.ui.Select; import java.util.Random; import java.util.concurrent.TimeUnit; import static org.junit.Assert.assertEquals; public class RegistrationHelper { public static final String EMAIL_VALIDATION_URL = "hopsworks-admin/security/validate_account.xhtml?key="; public static final String ADMIN = "HOPS_ADMIN"; public static final String USER = "HOPS_USER"; private static void gotoRegisterPage (WebDriver driver) { driver.manage().timeouts().implicitlyWait(1, TimeUnit.SECONDS); try { driver.findElement(By.name("registerForm")); } catch (NoSuchElementException \| Error e) { driver.findElement(By.linkText("Register")).click(); } driver.manage().timeouts().implicitlyWait(WebDriverFactory.IMPLICIT_WAIT_TIMEOUT, TimeUnit.SECONDS); } private static void registerTest(String firstName, String lastName, String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { boolean twoFactorEnabled = dbHelper.isTwoFactorEnabled(); if (twoFactor &&!twoFactorEnabled) { Helpers.enableTwoFactor(driver, dbHelper); gotoRegisterPage(driver); } Helpers.waitForElement(By.name("registerForm"), driver); driver.findElement(By.name("first_name")).sendKeys(firstName); driver.findElement(By.name("last_name")).sendKeys(lastName); driver.findElement(By.name("user_email")).sendKeys(email); driver.findElement(By.name("phone_number")).sendKeys("1234567890"); driver.findElement(By.id("id-password")).sendKeys(password); driver.findElement(By.name("user_password_confirm")).sendKeys(password); Select seqQA = new Select(driver.findElement(By.name("sec_question"))); seqQA.selectByVisibleText("Name of your first pet?"); driver.findElement(By.name("sec_answer")).sendKeys("pet"); driver.findElement(By.name("user_agreed")).click(); WebElement testUserElement = driver.findElement(By.name("test_user")); JavascriptExec.jsClick(driver, testUserElement); if (twoFactor) { driver.findElement(By.name("2FactorAuth")).click(); } driver.findElement(By.name("registerForm")).submit(); } private static void register(String firstName, String lastName, String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { gotoRegisterPage(driver); registerTest(firstName, lastName, email, password, twoFactor, driver, dbHelper); if (twoFactor) { assertEquals("Four steps, and you're there...", driver.findElement(By.id("two_factor_four_steps")) .getText()); driver.findElement(By.linkText("Ok")).click(); } else { Helpers.waitForElementVisibility(By.id("regSuccess"), driver); String successAttr = driver.findElement(By.id("regSuccess")).getAttribute("aria-hidden"); String errorAttr = driver.findElement(By.id("regError")).getAttribute("aria-hidden"); //assert no error msg assertEquals("true", errorAttr); assertEquals("false", successAttr); driver.findElement(By.linkText("Sign in")).click(); } } public static String registerUserTest(boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); String email = firstName + "@hopsworks.ai"; String password = "12345Ab"; registerTest(firstName, lastName, email, password, twoFactor, driver, dbHelper); return email; } public static String registerUser(boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); String email = firstName + "@hopsworks.ai"; String password = "12345Ab"; register(firstName, lastName, email, password, twoFactor, driver, dbHelper); return email; } public static void registerUser(String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); register(firstName, lastName, email, password, twoFactor, driver, dbHelper); } public static String registerUser(String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); String email = firstName + "@hopsworks.ai"; register(firstName, lastName, email, password, twoFactor, driver, dbHelper); return email; } public static void validateEmail(String key, WebDriver driver) { Helpers.driverGet(EMAIL_VALIDATION_URL + key, driver); assertEquals("You have successfully validated your email address, but your account still has to be approved " + "by an administrator. Hopefully soon!", driver.findElement(By.xpath( "(.//*[normalize-space(text()) and normalize-space(.)='Email Address Verification'])[1]/following::p[1]")) .getText()); } public static User createActivatedUser(String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { String email = registerUser(password, twoFactor, driver, dbHelper); User user = validateAndActivateUser(email, driver, dbHelper); Helpers.driverGet("hopsworks", driver); return user; } public static User createActivatedUser(String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { registerUser(email, password, twoFactor, driver, dbHelper); User user = validateAndActivateUser(email, driver, dbHelper); Helpers.driverGet("hopsworks", driver); return user; } public static User validateAndActivateUser(String email, WebDriver driver, DBHelper dbHelper) { User user = dbHelper.getUserByEmail(email); String key = dbHelper.getValidationKey(user.getEmail()); validateEmail(key, driver); dbHelper.activateUser(email); dbHelper.addGroup(user, USER); return user; } public static User createAdminUser(String password, WebDriver driver, DBHelper dbHelper) { User user = createActivatedUser(password, false, driver, dbHelper); dbHelper.addGroup(user, ADMIN); return user; } } source include/have_sjis.inc; source include/master-slave.inc; --disable_warnings drop table if exists t1; drop procedure if exists p1; --enable_warnings create table t1 (a varchar(255) character set sjis); create procedure p1 (in a varchar(255) character set sjis) insert into t1 values (a); SET NAMES binary; CALL p1 ('–\\'); select "--- on master ---";
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6832, 8788, 13, 8943, 432, 521, 9261, 273, 30904, 12473, 715, 247, 5796, 29445, 1728, 15, 380, 6963, 457, 84, 33129, 26614, 497, 275, 557, 3728, 285, 253, 2578, 19659, 6325, 15, 380, 5019, 273, 841, 2616, 1669, 18885, 17018, 7329, 281, 253, 6963, 457, 84, 49543, 3753, 13, 534, 41763, 275, 4162, 1458, 1797, 672, 253, 46709, 369, 34150, 281, 1302, 285, 4845, 275, 253, 20610, 273, 4693, 15, 3032, 1066, 12615, 369, 19779, 28, 344, 369, 6636, 342, 49782, 281, 5159, 253, 6963, 285, 11407, 327, 20610, 7061, 327, 1722, 2552, 15, 3032, 8788, 285, 2867, 13, 1690, 30904, 12473, 18732, 13, 369, 17571, 407, 253, 16834, 285, 3395, 4377, 8966, 29136, 457, 84, 15, 187, 187, 4553, 436, 2180, 253, 19887, 369, 13949, 908, 407, 253, 6963, 457, 84, 6122, 6393, 13, 665, 651, 11719, 3297, 275, 30904, 12473, 1309, 617, 29386, 1107, 16682, 703, 369, 247, 5974, 273, 253, 19520, 273, 1889, 1715, 15, 733, 369, 1309, 253, 5768, 273, 1458, 1671, 2299, 326, 253, 19887, 2959, 417, 8885, 1734, 672, 30904, 12473, 4546, 3167, 281, 4377, 8966, 29136, 285, 521, 747, 19538, 17467, 378, 1306, 1362, 323, 884, 1897, 15, 380, 4667, 7244, 327, 1638, 4223, 285, 29115, 281, 3162, 251, 2111, 327, 3307, 4223, 13, 253, 2456, 394, 19054, 273, 253, 50005, 641, 30307, 281, 253, 23399, 387, 18624, 11448, 7327, 15, 46365, 387, 30904, 12473, 8966, 369, 11580, 407, 247, 31896, 432, 10151, 29912, 665, 3982, 779, 884, 3475, 257, 285, 3387, 16396, 16682, 17467, 369, 3559, 342, 247 ]	, August 2015, table E.1. The estimated participation rates are not directly comparable between 2007 and 2013 because of revisions to the methodology. [12] For more information, see Stacy Dean and Dorothy Rosenbaum, “SNAP Benefits Will Be Cut for Nearly All Participants in November 2013,” Center on Budget and Policy Priorities, revised August 2, 2013, http://www.cbpp.org/cms/?fa=view&id=3899. [13] Neither of these two changes to states’ eligibility rules resulted from recent legislation. Both are state options from the 1996 welfare law. The Recovery Act suspended the three-month time limit for the rest of 2009 and 2010, but because of the high unemployment associated with the recession, most areas already were eligible for a waiver under longstanding rules. In January 2009 the Bush Administration clarified that states qualifying for the new Emergency Unemployment Compensation program would be treated the same as states qualifying for the Extended Benefits unemployment insurance program, which were eligible for statewide waivers under existing law. For more information on these two provisions, see Dorothy Rosenbaum, Stacy Dean, and Robert Greenstein, “Cuts Contained in SNAP Bill Coming to the House Floor Would Affect Millions of Low-Income Americans,” Center on Budget and Policy Priorities, revised September 17, 2013, http://www.cbpp.org/research/cuts-contained-in-snap-bill-coming-to-the-house-floor-would-affect-millions-of-low-income. [14] See Peter Ganong and Jeffrey B. Liebman, “The Decline, Rebound, and Further Rise in SNAP Enrollment: Disentangling Business Cycle Fluctuations and Policy Changes,” National Bureau of Economic Research, Working Paper 19363, August 2013, http://www.nber.org/papers/w19363.pdf?new_window=1. CBO estimates from the 2014 farm bill debate also confirm that a relatively small share of SNAP participants’ eligibility depends on these two rules. According to CBO, expanded categorical eligibility in all states, including those that adopted it before 2009, accounts for only about 2 percent of program costs. CBO also estimated that eliminating all waivers from the three-month time limit (not just those for areas with high unemployment because of the recession) would have cut SNAP participation in 2014 by less than 4 percent. [16] In 2007 8.8 percent of the population received SNAP benefits. The share peaked at about 15 percent in 2013. Based on CBO’s SNAP projections and the Census Bureau’s population projections, the share will fall to 9.5 percent in 2026. [17] In addition to the economy and SNAP-related policy changes, other factors will need to be considered in assessing caseload trends. For example, state implementation of the Affordable Care Act, which expanded Medicaid eligibility in many states and induced virtually every state to revise its automated eligibility systems and processes, may have indirectly affected SNAP enrollment in some states. [19] Ganong and Liebman, op. cit.; James P. Ziliak, “Why Are So Many Americans on Food Stamps?” in J. Bartfeld et al., editors, SNAP Matters: How Food Stamps Affect Health and Well Being, Stanford University Press, 2015; Marianne Bitler and Hilary Hoynes, “The More Things Change, the More They Stay the Same? The Safety Net and Poverty in the Great Recession,” Journal of Labor Economics, Vol. 34, Issue S1, 2016; and Jacob Alex Klerman and Caroline Danielson, “Can the Economy Explain the Explosion in the Supplemental Nutrition Assistance Program? An Assessment of the Local-level Approach,” American Journal of Agricultural Economics, 2016. [21] The decline in the unemployment rate over much of this period overstated the improvement in the labor market. Because people continued to drop out or stay out of the labor force even as the economy recovered, the share of the population age 16 and over with a job (the employment rate) has risen only modestly from its recession low. As Federal Reserve Chair Janet Yellen said in December 2015 when announcing the Federal Reserve was beginning to raise interest rates, “I continue to judge that there remains slack in the economy, margins of slack that are not reflected in the standard unemployment rate, and, in particular, I’ve pointed to the depressed level of labor force participation and also the somewhat abnormally high level of part-time employment.” See Federal Reserve Board of Governors, “Transcript of Chair Yellen’s Press Conference,” December 16, 2015, http://www.federalreserve.gov/mediacenter/files/fomcpresconf20151216.pdf.Thornbury Castle is a magnificent retreat located in South Gloucestershire that is proudly proclaimed to be the only Tudor castle to presently operate as a hotel, a unique novelty that serves as a powerful selling point. As someone who recently stayed at the castle I can personally endorse Thornbury as an incredible place to visit and should be added to the bucket list of all who read this. The History In July 1510 Edward Stafford, 3rd Duke of Buckingham, obtained a royal licence to undertake work at his manor of Thornbury, located on the edge of the Cotswolds. The manor had been in the Stafford family for generations and the ambitious duke sought to transform his pleasant retreat into a palatial home without rival anywhere else in the kingdom. The proud and arrogant Buckingham was a descendant of the Plantagenet kings of England and had an impeccable bloodline through which he was not only well-connected, but also exceptionally wealthy. Nonetheless he had effectively been exiled from holding any power at court due to the pre-eminence of Cardinal Thomas Wolsey and the king’s favourites such as Charles Brandon and William Compton. With an egotistical desire to attract attention and with money to burn, Buckingham set about a building campaign that would ensure his castle would be the grandest noble home in the kingdom. The reasons for Buckingham’s desire to base himself at Thornbury, as opposed to one of his many other estates throughout England, are unclear but may be connected in part to his childhood. The duke’s father, Henry Stafford, 2nd Duke of Buckingham, had been an ally of Richard, Duke of Gloucester, in 1483 and helped Gloucester claim the throne as Richard III. Within months the 2nd Duke turned against his king and launched a farcical rebellion to unseat Richard. After the collapse of his uprising the duke was captured and summarily executed in Salisbury. The young Edward Stafford’s uncertain future was somewhat secured when the seven-year-old’s wardship was given to Margaret Beaufort in 1486, the mother of the new king Henry VII and the esteemed matriarch of the Tudor Dynasty. It is a possibility Margaret placed the young boy at Thornbury Manor, a claim lent credence when taken into consideration the marriage of the duke’s mother Katherine Wydeville to Jasper Tudor, Duke of Bedford and uncle to the king. It is known that Jasper based himself at Thornbury and would die there on 21 December 1495. His ghost is stated to roam the property. After a childhood spent in close companionship with the royal family, Edward Stafford emerged into adulthood as a strong-headed and ostentatious character fully aware of his noble grandeur. It was such a boastful disposition that would inspire Thornbury Castle which was designed to rival the king’s own Hampton Court Palace as the greatest home in the kingdom. Attempting to upstage the king however was not a recommended tactic. Work was still ongoing in 1521, more than a decade after it had commenced, when the arrest of the duke suddenly caused tools to be downed and construction halted. The duke’s crime had been to rouse suspicion of treason in the mind of the increasingly paranoid king he had attempted to upstage – Henry VIII. By 1521 the king was entering his 30’s and had yet to produce a legitimate male heir. Thoughts were slowly beginning to form about the event of a succession crisis and many were allegedly turning their heads towards the Duke of Buckingham, who it may be argued had a greater claim to the throne than Henry VIII. A foreign ambassador stated admiringly ‘my lord of Buckingham, a noble man and would be a royal ruler’. Furthermore the duke possessed substantial wealth, evident from his transformation of Thornbury into a palatial home. The king’s finances meanwhile were in disarray and the treasury empty. The combination of these factors left Buckingham exposed to the king’s ruthless nature, which erupted in April 1521 when the duke was summoned to court and placed in the Tower of London. His downfall was swift; he was charged with intending to kill the king and executed on Tower Hill on 17 May. His wealth and property, including Thornbury Castle, was seized by the crown and became King Henry VIII’s. After this period the castle was occasionally used by the king’s daughter Mary, who would regularly stay in Thornbury during her teenage years whilst she was a student of the Bishop of Exeter. It was during the summer of 1535 however that the castle received notoriety when Thornbury played host to King Henry VIII and his new queen Anne Boleyn for 10 days. The pair arrived on 14 August and departed to Acton Court on 22 August, the 50th anniversary of the Tudors accession to the throne at Bosworth Field. Whilst at Thornbury Henry was visited by a delegation from nearby Bristol who brought him 10 oxen and 40 sheep whilst Anne was presented with a
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247, 1770, 15, 309, 10141, 253, 2670, 2378, 390, 7019, 247, 2129, 1309, 326, 673, 533, 616, 497, 642, 11269, 15, 11243, 627, 369, 247, 1895, 342, 634, 2670, 285, 326, 651, 5513, 2139, 690, 952, 497, 11926, 670, 634, 5928, 15, 3667, 2196, 15, 187, 187, 2773, 310, 4107, 1170, 21472, 2, 3954, 13, 309, 5082, 457, 85, 971, 281, 1408, 2439, 326, 15906 ]	the smoothing inertial projection neural network (SIPNN) algorithm for solving the proposed general model. Under certain conditions, the proposed algorithm can converge to a stationary point. Finally, convergence behavior and successful recover performance experiments and a comparison experiment confirm the effectiveness of the proposed SIPNN algorithm.// clang-format off // This source file is part of the Swift.org open source project // // Copyright (c) 2014 - 2015 Apple Inc. and the Swift project authors // Licensed under Apache License v2.0 with Runtime Library Exception // // See http://swift.org/LICENSE.txt for license information // See http://swift.org/CONTRIBUTORS.txt for the list of Swift project authors // /* CFPreferences.h Copyright (c) 1998 - 2015 Apple Inc. and the Swift project authors / #if!defined(__COREFOUNDATION_CFPREFERENCES__) #define __COREFOUNDATION_CFPREFERENCES__ 1 #include <CoreFoundation/CFBase.h> #include <CoreFoundation/CFArray.h> #include <CoreFoundation/CFString.h> CF_IMPLICIT_BRIDGING_ENABLED CF_EXTERN_C_BEGIN CF_EXPORT const CFStringRef kCFPreferencesAnyApplication; CF_EXPORT const CFStringRef kCFPreferencesCurrentApplication; CF_EXPORT const CFStringRef kCFPreferencesAnyHost; CF_EXPORT const CFStringRef kCFPreferencesCurrentHost; CF_EXPORT const CFStringRef kCFPreferencesAnyUser; CF_EXPORT const CFStringRef kCFPreferencesCurrentUser; / NOTE: All CFPropertyListRef values returned from CFPreferences API should be assumed to be immutable. / / The "App" functions search the various sources of defaults that apply to the given application, and should never be called with kCFPreferencesAnyApplication - only kCFPreferencesCurrentApplication or an application's ID (its bundle identifier). / / Searches the various sources of application defaults to find the value for the given key. key must not be NULL. If a value is found, it returns it; otherwise returns NULL. Caller must release the returned value / CF_EXPORT CFPropertyListRef CFPreferencesCopyAppValue(CFStringRef key, CFStringRef applicationID); / Convenience to interpret a preferences value as a boolean directly. Returns false if the key doesn't exist, or has an improper format; under those conditions, keyExistsAndHasValidFormat (if non-NULL) is set to false / CF_EXPORT Boolean CFPreferencesGetAppBooleanValue(CFStringRef key, CFStringRef applicationID, Boolean keyExistsAndHasValidFormat); /* Convenience to interpret a preferences value as an integer directly. Returns 0 if the key doesn't exist, or has an improper format; under those conditions, keyExistsAndHasValidFormat (if non-NULL) is set to false / CF_EXPORT CFIndex CFPreferencesGetAppIntegerValue(CFStringRef key, CFStringRef applicationID, Boolean keyExistsAndHasValidFormat); /* Sets the given value for the given key in the "normal" place for application preferences. key must not be NULL. If value is NULL, key is removed instead. / CF_EXPORT void CFPreferencesSetAppValue(CFStringRef key, CFPropertyListRef value, CFStringRef applicationID); / Adds the preferences for the given suite to the app preferences for the specified application. To write to the suite domain, use CFPreferencesSetValue(), below, using the suiteName in place of the appName / CF_EXPORT void CFPreferencesAddSuitePreferencesToApp(CFStringRef applicationID, CFStringRef suiteID); CF_EXPORT void CFPreferencesRemoveSuitePreferencesFromApp(CFStringRef applicationID, CFStringRef suiteID); / Writes all changes in all sources of application defaults. Returns success or failure. / CF_EXPORT Boolean CFPreferencesAppSynchronize(CFStringRef applicationID); / The primitive get mechanism; all arguments must be non-NULL (use the constants above for common values). Only the exact location specified by app-user-host is searched. The returned CFType must be released by the caller when it is finished with it. / CF_EXPORT CFPropertyListRef CFPreferencesCopyValue(CFStringRef key, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); / Convenience to fetch multiple keys at once. Keys in keysToFetch that are not present in the returned dictionary are not present in the domain. If keysToFetch is NULL, all keys are fetched. / CF_EXPORT CFDictionaryRef CFPreferencesCopyMultiple(CFArrayRef keysToFetch, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); / The primitive set function; all arguments except value must be non-NULL. If value is NULL, the given key is removed / CF_EXPORT void CFPreferencesSetValue(CFStringRef key, CFPropertyListRef value, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); / Convenience to set multiple values at once. Behavior is undefined if a key is in both keysToSet and keysToRemove / CF_EXPORT void CFPreferencesSetMultiple(CFDictionaryRef keysToSet, CFArrayRef keysToRemove, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); CF_EXPORT Boolean CFPreferencesSynchronize(CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); / Constructs and returns the list of the name of all applications which have preferences in the scope of the given user and host. The returned value must be released by the caller; neither argument may be NULL. / CF_EXPORT CFArrayRef CFPreferencesCopyApplicationList(CFStringRef userName, CFStringRef hostName) CF_DEPRECATED(10_0, 10_9, 2_0, 7_0); / Constructs and returns the list of all keys set in the given location. The returned value must be released by the caller; all arguments must be non-NULL / CF_EXPORT CFArrayRef CFPreferencesCopyKeyList(CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); CF_EXTERN_C_END CF_IMPLICIT_BRIDGING_DISABLED #endif /! __COREFOUNDATION_CFPREFERENCES__ */ // clang-format on The Hybrid Beetle Crown I made this guy as an experiment. My lovely Arum is modeling it. This Silver rhino beetle has 8 legs, assembled from 3 different beetle species. The articulated vertebrae tail is detachable. It actually belongs to another project of mine, but I attached it to the bug out of curiosity and loved the look of it. Because, why not? Eeee! I know we’re not supposed to use this word, but he looks so ‘COOOOOL’ on and off the doll! I love how his tail wraps around her neck in the 3rd pic. I think he’s kinda CUTE! – another no-no word?! >o< Well, if this was an experiment, it’s a fabulously successful one! Marina, your imaginative creations never cease to amaze me. The vertebrae tail is awesome. I’d really love to see the project that this was actually meant for as well! OMG, that is absoutely, divinely, stunningly amazing. I love bugs of any sort, but this is beyond wonderful. Sorry for gushing, but this is Seriously Fabulousâ™¥â™¥â™¥ Any chance of a large tarantula type spider? :) It’s incredibly beautiful! I think it’s my favourite headdress so far! I love how the beetle contrast with the more feminine and delicate curves of the piece. It reminds me a bit of Alexander McQueen’s aesthetic. Beautiful. Who would think a beetle could look so gorgeous and elegant and still very ‘bug-ish’ all at the same time? True art. I love it! I love all of the detail and sharp look about it (yes I thought of Alexander McQueen for a moment also). Thanks for the pictures! Your last 4 or 5 blog entries just appeared all at once. I thought maybe you were on vacation but they span almost a month. I checked the site once or twice a week during that time but their were no updates. Perhaps there was a problem with your site and that would explain why some people were worried about your absence. Regards. That is freaking stunning! Now, I wouldn’t want to run across that creature
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253, 6517, 273, 973, 14, 16894, 14300, 15, 47042, 25988, 13, 1690, 43870, 1975, 6803, 285, 20967, 13, 9965, 13, 285, 46513, 27163, 13, 497, 5196, 1046, 374, 1107, 15, 36745, 8191, 7578, 369, 2797, 432, 5014, 387, 1016, 4143, 13, 285, 253, 1263, 369, 7012, 407, 253 ]	, Facebook will need to prove that it can transition Libra to a more permissionless model with actual decentralization. Currently, the criteria to be a validator is squarely in the hands of only 28 multi-national firms. The network is more comparable to a consensus model by corporate entities rather than anything remotely comparable to decentralization. More Cryptocurrency Exposure through Facebook Expected However, Lubin did identify some positive factors. For example, the Libra will inevitably expand the growth of users in the cryptocurrency space. It will also make financial payments much easier. With this in mind, “talented UX designers could reduce the friction of using cryptocurrency” Lubin said. “Managing private keys, understanding gas payments and installing crypto browser plugins could be as simple as pressing ‘send’ in WhatsApp.” The Libra is definitely not the end-all, but it could be a catalyst for actual decentralized solutions. Ultimately, it all comes down to trust. Facebook has made a poor attempt at remedying the public’s dislike of the social media giant in the wake of the Cambridge Analytica scandal. The fallout of that scandal has exposed the extent to which Facebook mines our data. With Libra, the social media giant will also be able to track our payment history. Therefore, Lubin is right to say that Facebook’s biggest problem today is trust. Hopefully, the Libra will merely bring visibility to the cryptocurrency industry rather than take over global payment systems. Do you believe Lubin’s assessment of the Libra is correct? Let us know your thoughts in the comments below.Surgical cutting or resection devices with drive units and rotating blades or burrs are commonplace in endoscopic surgery. Many current devices include a reusable drive unit and disposable rotating blades, burrs, or other attachments that are configured to couple to the reusable drive unit. During an endoscopic surgery, a surgeon may unknowingly apply forces to an instrument that have the potential of damaging the instrument or causing complications to the surgical procedure when using instruments of the previously existing designs. It would be advantageous to provide surgical instruments for endoscopic surgery that are capable of monitoring forces applied to the instruments. It may be further advantageous to have the capability to provide alerts of one or more types that notify a user when load limits that have been set for forces applied to the instruments have been reached. Some improved embodiments may include methods of calibrating a cutting tool with integrated force sensors to provide an alert when load limits are reached and methods of calculating loads applied to a cutting tool.Tag Archives: First day of school Today was the first day of the 2012-2013 school year. I dropped off Mary at the middle school gate, walked Jake to our local elementary school and into his new class, and since Emily is in high school I just gave her a firm kick out the front door. After my kids were tightly locked down into their three respective LA Unified schools, I came home, poured myself another cup of coffee and posted the following to my Facebook page: “It feels so weird to have the house to myself.” I hit “post” and then proceeded to read my friends’ News Feed for the morning. That’s when I realized I deserved the Worst Mother of the Year Award. Every single post of every single parent of a school-aged child had already uploaded a photo of their little angel’s first day of school. The kiddos were carrying Angry Bird lunch boxes and had Dora the Explorer backpacks over their shoulder blades and their spotless shoes were glittering and their shiny outfits were so new the tags were probably pulled off on the way to class. They were posing with old friends and new teachers, clutching siblings, and wiping the tears away from their sobbing parents. I, on the other hand, had completely forgotten about that precious Kodak moment. And now it was too late. It’s not like I could barge into my 16-year old’s French III class with my iPhone blazing. “Excusez-moi, Madam,” I could have said, and that would be the end of it since I don’t speak French. Then I’d take a quick snapshot of my daughter hiding under her desk. For the rest of her high school career, she would be known as That girl with the crazy paparazzi mom. I wouldn’t have been allowed to sneak into my 11-year old’s drama production class and loudly proclaim to her teacher that being the thespian that he is, he should understand why I must stop the class in their tracks from learning a Shakespeare sonnet or a David Mamet play or some improv demonstration where they all pretend to be caterpillars just so my daughter can be seen on the big screen (big depending on how large your computer monitor is). Normally I humiliate her just by breathing. This stunt would have pushed her so far over the edge that she probably have come home and tried to OD on gummy vitamins. And now that my baby boy is a big 1st grader, he’d be completely mortified if I popped into his new class and interrupted a lively reading of Junie B. Jones. “Stand over here next to Hendrix and say ‘cheese!’” Then I’d reposition him and shove another of his soon-to-be-former friends into the group. “Let’s do another one with Charlotte since you weren’t smiling.” Then he’d excuse himself to go to the little boys’ room and never come back. I could have had my first day of school Facebook photos. But alas, I missed my moment. So here’s my re-creation: I took it after my kids got home. Notice that Emily and Mary are already wearing their pajama bottoms. It’s too late to capture that first day of school moment. But at least I still have time to embarrass my kids. 718 S.E.2d 151 (2011) Correna C. HOWE v. Bradley Earl HOWE. No. 415P11. Supreme Court of North Carolina. October 6, 2011. Bradley E. Howe, for Howe, Bradley Earl. 152 Correna C. Howe, for Howe, Correna C. ORDER Upon consideration of the notice of appeal from the North Carolina Court of Appeals, filed by Defendant on the 23rd of September 2011 in this matter pursuant to G.S. 7A-30 (substantial constitutional question), the following order was entered and is hereby certified to the North Carolina Court of Appeals: the notice of appeal is "Dismissed ex mero motu by order of the Court in conference, this the 6th of October 2011." Upon consideration of the petition filed on the 23rd of September 2011 by Defendant in this matter for discretionary review of the decision of the North Carolina Court of Appeals pursuant to G.S. 7A-31, the following order was entered and is hereby certified to the North Carolina Court of Appeals: "Denied by order of the Court in conference, this the 6th of October 2011." Introduction {#S1} ============ The biological bases of obesity-related behaviors are poorly understood. Popular culture and the media perpetuate a 'headless, hungry and unhealthy' stereotype of the overweight individual as weak-willed, susceptible to the temptation of high calorie foods and prone to ill health^[@R1]^. However, it is unclear whether a common biological mechanism underlies predisposition to obesity as well as impulsive behavior and a preference for calorie-dense foods. This question is especially relevant in the context of aging as several adverse health outcomes are associated with obesity in the elderly ^[@R2]--[@R4]^. We report on the associations between the common obesity risk variant (rs1421085 single nucleotide polymorphism) in the fat mass- and obesity-associated gene, FTO,* and longitudinal changes in adiposity, brain function, impulsivity and macronutrient intake in the Baltimore Longitudinal Study of Aging (BLSA)^[@R5]^. [Figure 1](#F1){ref-type="fig"} summarizes the study design. First, we examined whether FTO genotype influenced trajectories of body mass index (BMI) during aging. Second, using serial ^15^O-water positron emission tomography (PET), we compared longitudinal changes in regional resting-state cerebral blood flow (rCBF), an established marker of neuronal activity^[@R6]^, between obesity-related risk allele carriers (FTO+) and non-carriers (FTO−). Then, based on differences in the regional pattern of longitudinal changes in rCBF between FTO risk and non-risk groups, we asked whether FTO genotype influences longitudinal changes in impulsivity and dietary patterns during aging. Materials and Methods {#S2} ===================== Participants {#S3} ------------ The BLSA is a prospective cohort study of community dwelling volunteer participants in Baltimore, beginning in 1958, and is one of the largest and longest-running longitudinal studies of aging in the United States ^[@R5],\ [@R7]^. The community dwelling unpaid volunteer participants are predominantly white, of upper-middle socioeconomic status, and with an above average educational level. In general, at the time of entry into the study, participants had no physical and cognitive impairment (i.e. Mini-Mental State Examination (MMSE) score ≤ 24) and no chronic medical condition with the exception of well-controlled hypertension. Detailed examinations, including neuropsychological assessment and neurological, laboratory, and radiological evaluations, were conducted every 2 years. Written informed consent was obtained from participants at each visit, and the study was approved by the
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253, 27113, 273, 34159, 9600, 285, 3542, 8191, 7578, 369, 2797, 432, 512, 5014, 2720, 281, 253, 1263, 15, 187, 187, 11, 1672, 657, 6073, 11, 4679, 1712, 4538, 25, 94, 187, 22873, 187, 187, 1166, 5343, 1363, 313, 10722, 2363, 13, 9901, 1107, 28, 2363, 2491, 13, 5976, 283, 3141, 1107, 10, 342, 16529, 17451, 267, 12382, 313, 25, 9646, 3719, 285, 898, 9646, 6490, 10, 285, 247, 18258, 1979, 3687, 685, 884, 1186, 2188, 275, 9080, 497, 17692, 10804, 34373, 432, 29677, 48737, 10043, 13160, 2683, 552, 4675, 875, 5080, 4022, 285, 3978, 4240, 15, 12493, 1907, 29518, 13215, 390, 37085, 4918, 497, 417, 13410, 15, 380, 2644, 18258, 13, 25547, 48448, 342, 4618, 1980, 35845, 390, 278, 4740, 20755, 13, 369, 4845, 275, 247, 8781, 285, 4745, 25266, 13, 1293, 49632, 1971, 13, 327, 247, 495, 1186, 53, 3382, 14478, 25152, 313, 34, 2942, 6156, 19685, 13, 6778, 2824, 27147, 13, 9567, 13, 16333, 10, 970, 247, 2133, 18783, 323, 6447, 6322, 285, 247, 4567, 14, 10531, 815, 833, 3781, 11452, 18783, 323, 2625, 5481, 15, 31373, 48448, 7944, 497, 15471, 275, 253, 9145, 273, 11452, 18783, 15, 16315, 5377, 941, 497, 9288, 970, 247, 2014, 46092, 353, 37556, 4653, 5479, 3425, 3951, 1311, 21, 3725, 342, 22563, 673, 313, 3125, 10, 273, 337, 9519, 1186, 983, 13, 7392, 673, 313, 5428, 10, 273, 11084, 1186, 983, 13, 27277, 941, 2792, 13, 9879, 16992, 273, 5307, 14878, 13, 9879, 14835, 4294, 387, 374, 15, 25 ]	could be reduced to 68% (46--72%) or to 28% (6--43%) of the original scan time compared to S/N^2^ Weighting and Equal Weighting respectively.Figure 5SNR as a function of the number of repeated acquisitions. The mean SNR obtained using AOC and S/N^2^ Weighting for PUFA spectra acquired from five patients is plotted as a function of the number of repeated acquisitions. Baseline SNR is also shown. The dotted line shows the maximum average baseline SNR (SNR = 10.4) and maximum average SNR using S/N^2^ Weighting (SNR = 14.1) after averaging for 256 acquisitions. To achieve the same SNR using AOC, the acquisition time can be reduced to 28% (6--43%) compared to baseline. If noise correlation is not ignored, the acquisition time can be reduced to 68% (46--72%) (1.5 times faster) compared to S/N^2^ Weighting. Values are given as median and range in parenthesis. Standard errors for each line are shown in Supplementary Fig. [S2a,b](#MOESM1){ref-type="media"}. Discussion {#Sec6} ========== In this work, we compared current algorithms for combining PUFA spectra acquired using MQC MRS on phased array coils in breast cancer. AOC yielded the highest SNR improvement in excised breast tumours, healthy volunteers and patients. Moreover, AOC showed robustness against voxels with relatively low baseline SNR and was not affected by the presence of contamination lipid signal. AOC can be used for breast tumours with wide range of volumes, PUFA, water or fat contents, demonstrating the applicability in clinical settings. AOC was the optimal algorithm consistently in both ex vivo and in vivo experiments. For ex vivo experiments, there was a clear difference in SNR improvement between the noise decorrelated algorithms (an average of 44% from AOC and nd-comb) and the linear algorithms (an average of 30% from S/N^2^ Weighting, S/N Weighting, and Signal Weighting). Among the linear algorithms, S/N^2^ Weighting had the best SNR improvement as predicted theoretically^[@CR9]^ followed by S/N Weighting and Signal Weighting as shown in brain MRS^[@CR9]^. WSVD gave a large variance of SNR improvement ranging from −100 to 77% dependent on the baseline SNR, since WSVD uses the PUFA spectra to estimate the weighting (reference spectra in AOC and nd-comb). A minimum baseline SNR (7.5 in this study) is required for WSVD to accurately identify the PUFA peak (phase and amplitude) in order to yield comparable SNR improvement as other noise decorrelated algorithms. This is in agreement with the literature findings in brain MRS where WSVD was shown to give comparable results with other noise decorrelated algorithms at high SNR levels but worse performance at low SNR^[@CR11]^. AOC gave significantly higher SNR improvement compared to nd-comb, because nd-comb eliminates correlated noise before linear combination while AOC balances the signal against the overall noise^[@CR10]^. For healthy volunteers, the difference in SNR improvement between the noise decorrelated algorithms and the linear algorithms was larger (up to 47%) due to higher noise correlation found in vivo. WSVD was susceptible to the presence of contamination lipid signal (for 4 out of 30 data), as found in brain MRS acquired near the skull^[@CR25]^ whilst comparable to AOC for data with no lipid contamination. In patients, the difference between noise decorrelated algorithms and the linear algorithms was 28%. WSVD was susceptible to the presence of contamination signal in two patients and the low baseline SNR in the remaining three patients. AOC gave significantly higher SNR improvement compared to each of the algorithms apart from nd-comb. However, caution should be practised in interpreting these findings due to the small sample size. Based on consistent results among the experiments, AOC is most likely to provide the maximal SNR improvement in patients without susceptibility to low baseline SNR or contamination signal. We examined the relationship between AOC and experimental conditions, including PUFA content, voxel volume and water/fat ratio. There was no dependency of AOC performance on voxel volume, and hence SNR level, in agreement with simulated and acquired MRS in the brain^[@CR11]^. There was also no dependency of AOC on PUFA content and water/fat ratio in tumour specimens nor on PUFA content in healthy volunteers. In contrast, WSVD showed dependency on baseline SNR as well as voxel volume, confirming the categorical difference shown in group analysis. Therefore, AOC is functional in a wide range of breast tumour sizes and PUFA, water or fat contents, making it the ideal choice for clinical applications. AOC, although independent from biochemical environment and voxel size in our study, is affected by voxel location^[@CR10]^. Voxels, centred on the tumour, were positioned at the isocentre in ex vivo experiments. However, positioning the voxels at the isocentre was not feasible for in vivo experiments, leading to a wider signal disparity across coil elements, and in turn to a more pronounced SNR improvement, as shown in brain MRS studies^[@CR9],[@CR10]^. The variability in SNR improvement observed in vivo was higher than ex vivo due to the varying voxel location across participants, and possibly the physiological differences across individuals. In patients, the variability in SNR and acquisition time improvement was additionally associated with the limited sample size of 5. Future studies will benefit from investigations on SNR and acquisition time improvement conducted on larger patient cohorts. Enhanced SNR can be used to improve the accuracy of PUFA quantification, trade for reduced acquisition time, or enhance acquisition voxel volume. In comparison to Equal Weighting, AOC reduces acquisition time to approximately a quarter (median: 28%, range: 6--43% of original acquisition time) to maintain same output SNR, or improves SNR by 61% (34--105%) with same scan duration (equivalent to a reduction of voxel volume to 62% or 85% in each dimension). We also compared AOC with S/N^2^ Weighting as a non-noise decorrelated algorithm yielding the highest SNR in our study among the rest of the linear algorithms. In that case, acquisition is 1.5 times faster (AOC reduces acquisition time to 68% (56--71%) compared to S/N^2^ Weighting) to maintain same output SNR, or SNR is improved by 24% (4--28%) with same scan duration. These results show that noise correlation in breast MRS should be considered to achieve an optimised combination. A fast acquisition would be clinically valuable for elderly patients, who might experience difficulties remaining still in prone position or maintaining shallow breathing. Furthermore, the enhanced SNR would allow the assessment of small tumours more prevalent in breast cancer following the introduction of screening programmes. Reduced scan time would also be valuable for PUFA MR spectroscopic imaging (MRSI) when assessment of the whole diseased breast is necessary^[@CR4]^. However, further analysis should be conducted to evaluate AOC performance on PUFA MRSI. This study was limited on a single scanner and future work will benefit from multi centre studies on larger patient cohorts using scanners from different vendors, magnetic field strength, and breast coils. However, we deployed different coils for data collection between ex vivo and in vivo experiments with the results demonstrating the applicability of the algorithms under diverse conditions. The tumours studied in this work were limited to invasive ductal carcinoma with large size, and future investigation should be carried out in smaller tumours and other phenotypes. However, invasive ductal carcinoma accounts for approximately 75% breast cancer cases^[@CR26]^, and the tumour size in this study is representative of typical patient population requiring MR scan. AOC, among current algorithms, provided the maximum SNR improvement and is robust against low SNR or contamination signal. The derived SNR improvement was not dependent on experimental conditions of PUFA, water and fat content or voxel volume. Hence AOC is the optimal algorithm for PUFA spectra acquired using MQC MRS in breast to improve quantification accuracy, reduce acquisition time and reduce acquisition voxel volume. Methods {#Sec7} ======= Experiments were conducted in freshly excised human breast tumours, healthy female volunteers and patients with breast cancer. The ex vivo and in vivo studies were approved by the North West -- Greater Manchester East Research Ethics Committee (REC reference: 16/NW/0032) and the North of Scotland Research Ethics Service (REC reference: 16/NS/0077) respectively. All experiments were conducted in accordance with the Declaration of Helsinki guidelines and written informed consent was obtained from all participants prior to the study. Ex Vivo experiments {#Sec8} --------------------- 17 female patients (mean age, 61 years; age range, 42--78 years) with invasive ductal carcinoma (8 grade II and 9 grade III) and a tumour size greater than 10 mm in diameter were enrolled consecutively from Aberdeen Royal Infirmary hospital between February 2016 and June 2017. Patients having undergone chemotherapy or hormonal therapy were not eligible. The whole tumour, freshly excised with wide local excision or mastectomy, was placed in a container and immediately scanned, without formalin treatment, on a 3 T clinical MRI scanner (Achieva TX, Philips Healthcare, Best, Netherlands) using a body coil for uniform transmission and a 32-element phased array receiver coil for signal detection. Whole excised tissues were positioned in the centre of receiver coil. PUFA data were acquired using a single voxel MQC PRESS sequence^[@CR4]^ with repetition time (TR) of 1250 ms, echo time (TE) of 130 ms, 1024 data points, spectral bandwidth of 2000 Hz, spectral editing frequency at 2.8
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940, 39078, 26644, 28250, 591, 35129, 6005, 458, 27060, 346, 34776, 2146, 11924, 3, 299, 258, 1033, 5741, 513, 4396, 460, 1073, 6978, 21622, 1073, 7940, 66, 310, 5378, 16170, 15, 308, 13077, 25183, 13, 2297, 965, 4054, 23611, 2459, 74, 46038, 419, 6167, 83, 4611, 6314, 26206, 1073, 540, 311, 2146, 29847, 1073, 2889, 5650, 26438, 1079, 13, 519, 24342, 1073, 26970, 377, 74, 1144, 2013, 49356, 1948, 335, 1342, 74, 1980, 74, 1161, 47060, 838, 80, 1073, 6385, 66, 458, 389, 8522, 5991, 260, 1595, 3422, 248, 299, 8005, 11924, 1980, 74 ]	; // LCA struct LCA { vector<int> e[MAXN]; int d[MAXN], p[MAXN][MAXM]; void dfs_(int v, int f) { p[v][0] = f; for (int i = 1; i < MAXM; ++i) { p[v][i] = p[p[v][i - 1]][i - 1]; } for (int i = 0; i < (int)e[v].size(); ++i) { int w = e[v][i]; if (w!= f) { d[w] = d[v] + 1; dfs_(w, v); } } } void init(int n, vector<int> e[MAXN]) { copy(e, e + n, this->e); d[0] = 0; dfs_(0, 0); } int up_(int v, int m) { for (int i = 0; i < MAXM; ++i) { if (m & (1 << i)) { v = p[v][i]; } } return v; } int lca(int a, int b) { if (d[a] > d[b]) { swap(a, b); } b = up_(b, d[b] - d[a]); if (a == b) { return a; } else { for (int i = MAXM - 1; i >= 0; --i) { if (p[a][i]!= p[b][i]) { a = p[a][i]; b = p[b][i]; } } return p[a][0]; } } } lca; vector<int> e[MAXN]; int stgcd(int a, int b) { int r = hld.r[a]; return st[r].gcd(hld.t[a] - hld.t[r], hld.t[b] - hld.t[r] + 1); } void stadd(int a, int b, int d) { int r = hld.r[a]; st[r].add(hld.t[a] - hld.t[r], hld.t[b] - hld.t[r] + 1, d); } int gao(int a, int b) { int ret = 0; // printf("gao(%d, %d)", a, b); while (true) { int c = hld.r[a] == hld.r[b]? b : hld.r[a]; // printf("[%d, %d] ==> [%d, %d]\n", c, a, hld.t[c], hld.t[a]); ret = ::gcd(ret, stgcd(c, a)); if (c == b) { break; } else { a = hld.p[c]; } } // printf(" = %d\n", ret); return ret; } void add(int a, int b, int d) { // printf("add(%d, %d, %d)\n", a, b, d); while (true) { int c = hld.r[a] == hld.r[b]? b : hld.r[a]; stadd(c, a, d); if (c == b) { break; } else { a = hld.p[c]; } } } int main() { int n, m, a, b, c, d; char op; scanf("%d", &n); for (int i = 1; i < n; ++i) { scanf("%d%d", &a, &b); e[a].push_back(b); e[b].push_back(a); } hld.init(n, e); lca.init(n, e); /* for (int i = 0; i < n; ++i) { printf("\t%d\t%d\t%d\n", i, hld.r[i], hld.t[i]); } */ for (int i = 0; i < n; ++i) { if (i == hld.r[i]) { st[i].init(hld.c[i].size()); } } for (int i = 0; i < n; ++i) { scanf("%d", &d); stadd(i, i, d); } scanf("%d", &m); for (int i = 0; i < m; ++i) { scanf(" %c%d%d", &op, &a, &b); c = lca.lca(a, b); // printf("LCA(%d, %d) = %d\n", a, b, c); if (op == 'F') { if (a == c) { printf("%d\n", gao(b, c)); } else if (b == c) { printf("%d\n", gao(a, c)); } else { printf("%d\n", ::gcd(gao(a, c), gao(b, c))); } } else { scanf("%d", &d); if (a == c) { add(b, c, d); } else if (b == c) { add(a, c, d); } else { add(a, c, d); add(b, c, d); stadd(c, c, -d); } } } return 0; } //Correct Answer //Execution Time: 17.80 di Mathias Hariyadi La facoltà di psicologia della Sanata Dharma (Usd) aveva indetto un incontro sul tema: “Lgbti: Siamo diversi, siamo unici e siamo Uno”. La sezione locale del Forum della società islamica ha imposto l’annullamento di un evento che “disonora l’islam”. Per un leader islamico i comportamenti sessuali “deviati” sono un “virus contagioso”. Jakarta (AsiaNews) - Dietro gravi minacce di estremisti islamici, l'università cattolica di Sanata Dharma (Usd) a Yogyakarta, nella provincia dello Java centrale, ha cancellato un seminario dedicato agli orientamenti sessuali "diversi", fra cui omosessualità, lesbismo, transgender. L'incontro, annullato in tutta fretta la scorsa notte, era stato promosso dalla facoltà di psicologia della Usd ed era previsto per il 27 settembre prossimo; tema del seminario "Lgbti: Siamo diversi, siamo unici e siamo Uno". Ieri il Forum della società islamica (Fui) ha annunciato che, in caso di mancata cancellazione dell'evento, avrebbe "infiltrato" propri elementi all'interno, per bloccare una discussione che avrebbe "disonorato l'islam". Johanes Eka Priyatna, rettore della Usd, conferma l'annullamento del seminario, al termine di un incontro a porte chiuse con i vertici della polizia, cui hanno partecipato anche docenti e membri del consiglio studentesco. Fra le città dell'Indonesia, Yogyakarta si è sempre distinta nel tempo per essere fra le più "tolleranti" e ospita dozzine di università di diversa ispirazione. Tuttavia, negli ultimi anni essa ha registrato episodi di intolleranza di natura confessionale, ad opera di gruppi estremisti musulmani locali che hanno preso di mira le comunità cattoliche e protestanti locali
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14, 3281, 14, 10539, 15, 8567, 32, 2040, 30, 5672, 10, 535, 186, 64, 4257, 22248, 45076, 428, 19662, 3213, 64, 187, 187, 18, 15, 496, 253, 1401, 39780, 23488, 390, 401, 4486, 424, 3213, 273, 253, 1401, 4257, 22248, 45076, 8200, 5731, 1491, 347, 6799 ]	-AzureVM output after adding a datadisk](images/update-azurevm-output-after-adding-a-datadisk.png?raw=true) _Update-AzureVM output after adding a new datadisk_ <a name="install-vm-extension-powershell"></a> Now you will learn how to add extensions to the virtual machine just created. Microsoft Azure provides VM Extensions built by both Microsoft and trusted third-party providers to enable security, runtime, debugging, management, and other features you can take advantage of to increase your productivity with Azure Virtual Machines. For more details see [Azure VM Extensions and Features](https://msdn.microsoft.com/en-us/library/azure/dn606311.aspx). The Azure Virtual Machine Agent (VM Agent) is used to install, configure, manage and run Azure Virtual Machine Extensions (VM Extensions). The VM Agent is a secure, light-weight process that installs, configures, and removes VM extensions on instances of Azure Virtual Machines from the Image Gallery and on custom VM instances if they have the VM Agent installed. There are two Azure VM Agents, one for Windows VMs and one for Linux VMs. By default, the VM Agent is automatically installed when you create a VM from the Image Gallery, but you can also install the VM agent after the instance is created or install it in a custom VM image that you then upload yourself. You will now verify that the VM Agent is enabled in the virtual machine created in the previous steps, and after that install the Symantec Protection extension. Finally, you will verify that the extension was correctly installed on the virtual machine. All these steps will be carried out using PowerShell and using some of the same variables set previously. 1. To verify whether the VM Agent is enabled on the virtual machine, run these commands: ```PowerShell $vm = Get-AzureVM -ServiceName $cloudSvcName $vm.VM.ProvisionGuestAgent ``` The output of the first command should not return any errors, and the second command should be True. Running these commands will also set the $vm.VM variable, which will be used in upcoming steps to add the extension. >Note: If the value of the $vm.VM.ProvisionGuestAgent property is False, connect to the virtual machine and install the VM Agent. You can download it [here](<http://go.microsoft.com/fwlink/?LinkID=394789&clcid=0x409>). Then, set the value of the variable to True with the following snippets. > >```PowerShell >$vm = Get-AzureVM -serviceName $cloudSvcName -Name $vmname >$vm.VM.ProvisionGuestAgent = $TRUE >Update-AzureVM -Name $name -VM $vm.VM -ServiceName $cloudSvcName >``` Now you will install the Symantec endpoint protection extension. 1. Execute the following command to add the extension: ```PowerShell Set-AzureVMExtension -Publisher Symantec -ExtensionName SymantecEndpointProtection -VM $vm.VM -Version 12.* Update-AzureVM -ServiceName $cloudSvcName -Name $vmname -VM $vm.VM ``` Set-AzureVMExtension sets the properties for the extension about to be installed. Update-AzureVM is the cmdlet that installs the extension. The output of running all the commands up to now should look like this: ![Set-AzureVMExtension output](images/set-azurevmextension-output.png?raw=true) _Adding a VM Extension output_ 1. To verify that the extension was installed on the virtual machine, run the following command: ```PowerShell Get-AzureVMExtension -VM $vm.VM ``` The output of the command should look like this: ![Get-AzureVMExtension output](images/get-azurevmextension-output.png?raw=true) _Get-AzureVMExtension output_ <a name="connect-to-vm-powershell"></a> After you attach a disk to a virtual machine you need to initialize it so it's ready for use. To do so you will need to log in to the machine to finish the initialization of the new data disk attached. 1. Run the following command to create a remote desktop protocol file (rdp) and launch it. When prompted to log in, use the credentials for the administrator user you configured when creating the virtual machine. >Note: The location for the rdp file provided must exist, otherwise you will see an error. ```PowerShell Get-AzureRemoteDesktopFile -ServiceName $cloudSvcName -Name $vmname -LocalPath 'C:\myvmconnection.rdp' -Launch ``` This will launch the rdp, effectively starting the flow of connecting to the remote machine. ![Get-AzureRemoteDesktopFile output](images/get-azureremotedesktopfile-output.png?raw=true) _Get-AzureRemoteDesktopFile output_ 1. In the Remote Desktop Connection dialog box, click Connect. >Note:: You might need to wait until the virtual machine has booted for the rdp file to successfully connect and prompt for credentials. If so, retry by opening the rdp file from the location where it was saved until you are prompted for credentials. 1. Enter the user name and password for the Administrator user that was entered when creating the virtual machine (step 7) and click OK. ![Enter admin User credentials](images/enter-admin-user-credentials.png?raw=true) _Entering the admin user credentials_ 1. In the Remote Desktop Connection dialog box, click Yes to verify the identity of the remote computer. You can check "Don't ask me again for connections to this computer" if you do not want to see this dialog box again. ![Verify virtual machine identity](images/verify-virtual-machine-identity.png?raw=true) _Verifying the virtual machine identity_ 1. After a few seconds, the remote desktop window opens and starts setting up the session for the administrator user. Once it is finished, you will see the Server Manager Dashboard open, which you will use in the following steps to configure the data disk that you attached previously. For all other purposes, you could now work with this machine as you would with any other machine in your own environment. ![Using the remote virtual machine](images/using-the-remote-virtual-machine.png?raw=true) _Using the virtual machine_ <a name="configure-datadisk-powershell"></a> Now you will configure the data disk that you attached to the Virtual Machine. 1. In the Server Manager Dashboard that is open in the virtual machine, click File and Storage Services. ![Clicking File and Storage Services](images/click-file-and-storage-services.png?raw=true) _Clicking File and Storage Services_ 1. Once you are in the Servers pane of File and Storage Services, click Disks. ![Clicking Disks in File and Storage Services](images/clicking-disks-in-file-and-storage-services.png?raw=true) _Viewing the disks in File and Storage Services_ The disks available in the machine are listed. You will see one that is listed as Microsoft Virtual Disk, with the partition _Unknown_ and Capacity set to the size entered when the disk was created. 1. Right-click the disk and select Initialize. ![Initialize the disk](images/initialize-the-disk.png?raw=true) _Initializing the disk_ 1. Click Yes in the confirmation message box to confirm you want to continue erasing all data on the disk. ![Confirm initialization of disk](images/confirm-initialization-of-disk.png?raw=true) _Confirming initialization of the disk_ 1. After a short wait, the disk now has a Partition set. Right-click the disk and select New Volume. ![Creating new volume](images/creating-new-volume.png?raw=true) _Clicking New Volume in the context menu_ 1. Click Next in the New Volume Wizard dialog box that opens. 1. In the Server and Disk step of the New Volume Wizard, click Next. 1. In the Size step of the New Volume Wizard, update the volume size if desired and then click Next. ![New Volume Wizard - Size step](images/newvolumewizard-size-step.png?raw=true) _New Volume Wizard - Size step_ 1. In the Drive Letter or Folder step of the New Volume Wizard, update information as desired
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35134, 2205, 13, 285, 247, 3331, 273, 7477, 2210, 407, 285, 369, 751, 13, 2802, 1276, 310, 1469, 327, 32, 6049, 403, 368, 3811, 275, 436, 35390, 29200, 1244, 309, 369, 751, 13, 2802, 33989, 457, 85, 436, 752, 6569, 672, 952, 2118, 281, 12226, 29200, 3, 187, 187, 2374, 617, 2469, 7688, 27, 187, 3, 510, 5561, 14, 7873, 2181, 3395, 1077, 27009, 13, 751, 13, 39361, 15, 309, 1904, 457, 85, 871, 752, 309, 369, 2509, 15, 309, 816, 2238, 273, 3395, 326, 2181, 15, 380, 4707, 13, 326, 5561, 14, 7873, 2238, 273, 14898, 13, 816, 3811, 247, 7156, 15, 733, 2238, 273, 2335, 689, 15, 733, 3053, 562, 1077, 15377, 285, 840, 309, 3531, 715, 247, 28224, 1894, 15, 1244, 309, 3053, 281, 1928, 751, 247, 28224, 1894, 449, 187, 187, 2374, 617, 2151, 285, 253, 2825, 11173, 27, 187, 3, 42, 1053, 457, 85, 871, 604, 597, 457, 306, 2326, 352, 13, 533, 597, 871, 670, 352, 15, 1583, 871, 670, 3253, 15, 659, 10461, 7336, 15, 309, 1053, 457, 85, 871, 2139, 4130, 310, 594, 17847, 342, 352, 449, 187, 187, 2374, 617, 8066, 466, 2624, 27, 187, 3, 3404, 806, 309, 1869, 309, 3261, 751, 13051, 15859, 390, 751, 247, 1165, 14, 22076, 390, 1633, 15, 1292, 1024, 309, 1928, 1663, 6422, 15, 309, 452, 247, 3331, 665, 310, 271, 13103, 13, 799, 314, 637, 13, 285, 344, 4566, 13, 2802, 1394, 871, 13, 690, 2255, 2624, 616, 4707, 285, 352 ]	who looks at it and touches it, You do not allow any one to touch you in a way that you do not like.) Let us teach our sons, that rape is bad, and they have their responsibilities towards women. Cataract is the clouding of the lens in the eye that effects vision. Most cataracts are related to aging. Risk factors are diseases like diabetes, personal behavior such as smoking, alcohol use, and environmental factors like prolonged exposure to ultraviolet sunlight. According to the 3rd National Blindness Survey done in 2002, the top three causes of visual impairment are cataract, error of refraction, and glaucoma. Cataract is the number one cause of reversible blindness in the country. What are the symptoms of cataract? Cloudy or blurry vision Colors seem faded Glare. Headlights, lamps, or sunlight may appear too bright. A halo may appear around lights. Poor night vision Double vision or multiple images in one eye Frequent prescription changes in your eyeglasses or contact lenses. My mom was one of these Filipinos affected by cataract; she’s 73 years old and had undergone cataract operation with lens implant on both eyes a month ago. She was so fortunate to been under the care of an ophthalmologist, who is committed in providing the highest quality eye care to his patients. Her ophthalmologist, is diplomate eye specialist Dr Noel J. Lacsamana. Aside from his comprehensive treatment he provides to his patients, Dr Noel J. Lacsamana is on the forefront of disseminating information about eye health through several radio programs. Thank you Dr. Noel J. Lacsamana, for all your good deeds not just to my mom but for people from all walks of life, which you have cared for and treated. My mom can’t thank you enough for her better sight. You have definitely made a difference in the lives of many. Tang’s search for the future faces of Philippine film starts today. The theme for the first-ever KiddiCine Film Festival is “Because I Can”. Tang calls on children aged seven to ten years old to send in their short stories that will be the basis of their film. They can draw a picture, take a photo and write up the best, most inventive and most creative ideas to capture the attention of the Screening Committee who will be judging entries based on Creativity, Originality and Adherence to the Theme. Entries should be composed of a completed application form (with a short summary of the story) and an endorsement letter from the parents / guardian. All these have to be sent as “Tang KiddiCine Film Entry” to Ogilvy and Mather, Philippines, 25/F Picadilly Star Building, 4th Avenue corner 27th St, Fort Bonifacio Global City, Taguig City 1634 or you can also send entries online. For more information on contest requirements and to download the form, you may go online to www.facebook.com/tangkiddicine or search for Tang KiddiCine on www.facebook.com. Deadline is on October 28, 2010.Due to their favorable photophysical and spectral properties, complexes of lanthanide ions (particularly Terbium and Europium) offer significant advantages over organic fluorescent dyes. Compared with traditional organic fluorescent materials, the lanthanide coordination compounds have the following properties - long life-time, a large Stokes shift, and sharp fluorescent peak profiles. Due to these attractive properties, time-resolved reagents based on lanthanide fluorescence have been created. However, existing lanthanide products have not been fully successful in producing products with sufficient stability and brightness to compete with conventional organic fluorophores. Under this Phase I SBIR, Lumiphore will develop a Europium (Eu) fluorescent reporter based on the novel 1,2-HOPO sensitizing unit. The proposed reporter (Lumi4-Eu) will have exceptional photophysical and stability characteristics that will set a new benchmark for Eu reporters in a wide range of drug discovery, diagnostic, rapid sequencing and array applications. This research will result in a fluorescence reagent with exceptional stability, usability, and fluorescent properties that will expand the capabilities of time resolved fluorescent diagnostics by offering the second color of a duplex set of compatible, but complementary lanthanide reporters (the other being Lumiphore's terbium-based fluorescence reporter - Lumi4-Tb). Combining Lumi4- Eu and Lumi4-Tb will enable a new generation of time resolved fluorescence or time resolved Fvrster resonant energy transfer (TR-FRET) based multiplex applications. Lumiphore will use this technology to develop a rapid, multiplexed immunoassay diagnostic platform. This platform holds the promise of exquisite sensitivities, speed, and versatility for the increasing demands of 21st century healthcare. PUBLIC HEALTH RELEVANCE: The proposed research when combines with Lumiphore's existing terbium-based fluorescence reporter (Lumi4-Tb) will impact public health by enabling highly multiplexed diagnostic assay formats that combine fast turnaround times and high assay throughput efficiency. These assays will be used in high throughput screening (HTS) drug discovery, genomic screening, rapid DNA sequencing, clinical diagnostics and fluorescence microscopy applications for both basic and applied biomedical research.11.50am So, 38 overs each, three bowlers can bowl eight overs, two seven, and the third Powerplay is ditched. The pitch is bone dry, there's a breeze blowing across the ground... 11.45am Massive cheers as the last of the covers comes off, and the Sri lankans come onto the outfield to warm-up... again. "At least the raindrops have been musical," says a bored Andrew Miller. "The one dripping next to me fits the soca rhythm very nicely..." Now we are told a 12.15pm start and 38 overs a side. Believe it when it happens.Immunological competence and nutritional status in patients with lung cancer. The rate of infection in patients with malignant disease is significantly higher than in patients with benign disease. To investigate whether immunological competence is impaired in patients with lung cancer, we assessed neutrophil function (chemotaxis, phagocytosis, bacterial killing activity, and superoxide production), monocyte function (phagocytosis and killing activity), lymphocyte subsets using flow cytometry, and proliferation of lymphocytes stimulated by phytohemagglutinin, concanavalin A, and pokeweed mitogen. Studies were performed on 22 untreated patients with lung cancer and 21 age-matched healthy volunteers. Nutritional status was assessed by Niederman's nutritional index. In patients with lung cancer neutrophil chemotaxis, monocyte phagocytosis and killing, proliferation of lymphocytes stimulated by phytohemagglutinin and concanavalin A, but not pokeweed mitogen, and the number of natural killer cells were significantly lower than in healthy volunteers, whereas gammadelta T cells were increased (p < 0.05). The mean score on Niederman's nutritional index was worse in patients than in healthy volunteers (p < 0.001). Our results suggest that the impaired immunological competence and undernutrition may be among the mechanisms causing increased susceptibility to infection in patients with lung cancer.Wrzosy, Greater Poland Voivodeship Wrzosy is a village in the administrative district of Gmina Doruchów, within Ostrzeszów County, Greater Poland Voivodeship, in west-central Poland. It lies approximately east of Doruchów, east of Ostrzeszów, and south-east of the regional capital Poznań. References WrzosyPamela Anderson Talks Hugh Hefner & Sex Tapes in ELLE April 2014 She's had her fair share of scandals over the years, and now Pamela Anderson is ready to open up about her controversial lifestyle in the April 2014 issue of ELLE magazine. During her interview with the mag, the former "Baywatch" star dished about everything from first meeting adult entertainment mogul Hugh Hefner to her infamous sex tape. Check out a few highlights from Miss Anderson's Q&A session below. For more, be sure to visit ELLE! On Hugh: "I told Hugh Hefner, ‘I have this crazy boyfriend.’ And Hef was like, ‘You’re not going anywhere with a crazy boyfriend,’ and so he put me in a mansion in Bel-Air with an opera singing Chinese maid, and I was driving a Bentley, and a friend of mine came by and was like, ‘What is going on? Why are you living in this mansion?’ And I was like, ‘Isn’t this what happens when people move to LA?’" On her past relationships: "The rock-star thing became very destructive, like, wow. I didn’t know what I was doing. I just kind of became that thing. The hair, that rock-star kind of lifestyle, just living a dream. It kind of took over. It started out very innocent and then I turned into a cartoon character. And I started to feel like a cartoon character." On her children and the sex tape: "I don’t know if they’ve seen it, but they know about it. They know about everything. Stupid Internet. I don’t know why everyone is so impressed with it." On her pixie cut: "At first I thought I looked like Anderson Cooper or like a Q-tip or something. But now I feel really powerful. I have a friend who is an awesome, studly man, and he goes, ‘You know, some women cut their hair and it
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342, 326, 1818, 15, 733, 6518, 479, 313, 3113, 10, 849, 359, 42513, 13, 849, 368, 1007, 387, 1841, 13, 849, 368, 971, 281, 513, 1841, 689, 15, 309, 908, 281, 452, 247, 861, 275, 619, 3906, 342, 253, 27373, 41994, 326, 753, 13, 2802, 2042, 368, 1053, 457, 85, 751, 1818, 13, 368, 457, 250, 1469, 281, 751, 3496, 11235, 11828, 1014, 1679, 15933, 407, 12284, 33655, 339, 5985, 273, 253, 1986, 2077, 8663, 15, 309, 574, 326, 598, 323, 247, 2257, 273, 4606, 13, 533, 309, 1158, 1818, 310, 1663, 1774, 1425, 187, 187, 688, 7487, 253, 2165, 3085, 13, 39449, 24535, 13, 247, 3438, 42513, 285, 4760, 11570, 6423, 342, 253, 3236, 39699, 17117, 13, 556, 2326, 247, 1818, 275, 253, 13946, 2165, 15, 187, 187, 1628, 510, 9728, 13, 1014, 2620, 1107, 3622, 13, 369, 247, 15950, 9728, 13, 533, 352, 457, 84, 2489, 1014, 625, 594, 1806, 39449, 24535, 753, 15, 773, 510, 6887, 13, 253, 1039, 368, 9646, 247, 7482, 4450, 556, 281, 16821, 1818, 984, 627, 457, 84, 594, 1142, 625, 6887, 326, 368, 457, 250, 1469, 281, 452, 281, 9646, 15, 733, 457, 84, 247, 16055, 6637, 13, 253, 6095, 273, 253, 9728, 15, 18741, 13, 884, 1107, 3622, 13, 627, 497, 247, 2257, 273, 6671, 3515, 4500, 5842, 13, 6313, 4500, 15, 3954, 13, 359, 457, 250, 275, 35694, 14, 7872, 15, 380, 2165, 457, 84, 4391, 16821, 1425, 187, 187, 8195, 1818, 39449, 24535 ]	three months of life. These data showed a similar rate of growth between the CHD and control groups ([@bb0155]; [@bb0160]). However, 2D biometrics methods are global regional measures, as opposed to the analyses reported here, which reflect tissue-specific changes beginning prenatally at approximately seven weeks before our previous 2D neonatal measures. Additionally, 2D biometric measures have limitations in their correlation with 3D volumetry for tissue measures. For example, bifrontal diameter (2Dregional measure) and cortical gray matter volume (3D tissue-type measure) only have a correlation coefficient of 0.482 ([@bb0145]). Thus, this study expands our previous data by defining total and tissue volumetric changes from prenatal to postnatal imaging, which provides complementary information to our prior work regarding brain growth. 4.6. Limitations {#s0105} ---------------- This study has several limitations. First, the sample size is relatively small, which impacted the ability to define the relative contributions of specific tissue-types to longitudinal TBV, as well as the variance explained by relevant clinical factors. While exploratory analyses were undertaken, future studies with larger samples are needed to rigorously evaluate these relationships. Second, our sample includes a heterogeneous cohort of CHD that may have variable effects on brain development at different gestational ages, which could influence the timing and severity of fetal and infant impairments in brain development. Finally, our cohort had missing data at each MRI time point. We addressed this limitation with a random coefficients model, but there may be systematic differences between those subjects who did and did not undergo imaging at each time point. For example, infants deemed too unstable for pre- or post-operative MRI may have had the greatest deficits in volumetric measurements at this time point. Their findings might be better represented on the 3-month MRI results when these infants were more clinically stable and a larger number were able to undergo MRI scans. Despite these limitations, these data are the first to evaluate longitudinal changes in brain volume from prenatal to postnatal imaging and provide a foundation for future work investigating the timing of tissue-specific involvement in altered brain development. 5. Conclusions {#s0110} ============== This study demonstrated that infants with CHD have an altered trajectory of brain growth from fetal through neonatal and 3-month MRI. Importantly, by three months of age multiple tissue-types were involved, suggesting global disturbances in brain development that are likely multifactorial. The following is the supplementary data related to this article.Supplementary Fig. 1Longitudinal Imaging in Individual CHD Patients with and without Brain Injury. The top row represents the fetal MRI (A), neonatal MRI (B), and 3-month MRI (C) for Subject 5. The bottom row represents the fetal MRI (D), neonatal MRI (E), and 3-month MRI (F) for Subject 18. The white arrows demonstrate white matter injury, the white arrowhead demonstrates the left caudate infarct, the black arrows demonstrate bilateral intraventricular hemorrhage, and the black arrowhead demonstrates ventriculomegaly.Supplementary Fig. 1 This work was supported by the National Institutes of Health (NIH) Institute of Clinical and Translational Sciences (UL1 TR000448 and KL2 TR 000450) (C.O.), National Institute of Neurological Disorders and Stroke (K02 NS089852) (C.S.), National Institute of Biomedical Imaging and Bioengineering(R01EB018988) (A.G.), and the Eunice Kennedy Shriver National Institute Of Child Health & Human Developmentunder Award Number U54 HD087011 to the Intellectual and Developmental Disabilities Research Center at Washington University (B.L.S.); the Children\'s Discovery Institute of Washington University and St. Louis Children\'s Hospital (C.O. and C.S); the McKnight Foundation Technological Innovations in Neuroscience Award (A.G.); and a Career Development Award from the Office of Faculty Development at Boston Children\'s Hospital (A.G.). The content of this work is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors would like to thank Jennifer Brockmeyer and Reginald Lee for their assistance with recruitment and MRI analysis. [^1]: These authors contributed equally to this work. [^2]: Data are presented as mean (SD) or number (percentage), unless otherwise noted. Delivery and hospitalization characteristics are reported for 15 CHD subjects, as one subject transferred care to her local hospital prior to delivery. MRI characteristics were for those subjects with usable volumetric data. (−) Represents variables that were not applicable to the control population and could not be compared between groups. DM = diabetes mellitus, GA = gestational age, HTN = hypertension, PMA = postmenstrual age. [^3]: Data are displayed as median (interquartile range). [^4]: p \< 0.05. [^5]: AA = aortic atresia, AS = aortic stenosis, ASD = atrial septal defect, BT = Blalock-Taussig, DORV = double outlet right ventricle, d-TGA = dextro-transposition of the great arteries, HLHS = hypoplastic left heart syndrome, IVS = intact ventricular septum, L-TGA = levo-transposition of the great arteries, LV = left ventricle, MA = mitral atresia, MS = mitral stenosis, PA = pulmonary atresia, PDA = patent ductus arteriosus, RV = right ventricle, TOF = tetralogy of Fallot, TV = tricuspid valve, VSD = ventricular septal defect. [^6]: This subject transferred care back to her local hospital prior to delivery. [^7]: (−) Subjects unable to undergo MRI at that time point. BIS = brain injury severity, IVH = intraventricular hemorrhage, N/A = not applicable because perioperative MRI data not available, WMI = white matter injury. [^8]: MRIs with motion artifact precluding volumetric analysis. [^9]: Cardiac surgery was after the 3-month MRI for these subjects. [^10]: 3-month MRI was used for BIS score because cardiac surgery was 15 days prior to the 3-month MRI for this subject. [^11]: Preoperative atrial septostomy occurred in these subjects. Subject 18 had the septostomy before the preoperative MRI. [^12]: Data are displayed as the estimated mean (95% confidence interval) for the random coefficients model using the model estimates at the mean gestational age for each MRI time point. Mean gestational at fetal MRI was 32.7 weeks, at preoperative MRI was 39.7 weeks, and at 3-month MRI was 52.4 weeks. The percent difference is the difference in means relative to the control population. CER = cerebellum CGM = cortical gray matter, CSF = cerebrospinal fluid, SCGM = subcortical gray matter, TBV = total brain volume, WM = white matter. Lombardi: 'Able to stay in tune to the game' Michael Lombardi, the Browns’ new Vice President of Player Personnel, feels he benefitted from his experience with NFL Network. Michael Lombardi, the new vice president of player personnel for the Cleveland Browns, made his return to the NFL front office with Friday morning’s introduction after a five-year run with NFL Network and NFL.com. In working as an analyst for the NFL Network, Lombardi developed a unique perspective of the game that will help him in his new position with the Browns. “The great thing about NFL Network, and I’m really appreciative to them, is they afforded me an office at NFL Films, where I had the ability to watch football games and watch coach’s tape,” Lombardi said. “I was able to stay in tune to the game. Part of that, too, is to be able to have conversations with coaches all over the league about different teams, about their team. “It gives you perspective to look back, and any time you can take a step back from the game, look at it, adjust it, modify it, the NFL is about change every three years and you have to keep up with that change. It helped me (with) how we scout, how you look at things, how you want to do things over. I used to have a sign in my office with the Oakland Raiders that said, ‘If you don’t like change, you’re going to like irrelevance even less,’ by Eric Shinseki of the United States Army. I had that up for a lot of reasons, but I think change is really important.” In watching the game film, Lombardi, a former scout and player personnel director with the original Browns franchise, has seen a change in the NFL game. “The league, even five years ago, was a throwing league, but it’s become even more so,” Lombardi said. “The positions, the way you grade a draft board has to dramatically change because there’s so many more positions that you’re going to have to grade. It’s a broader spectrum, the requirements of the league. Remember, 10 years ago, there were a lot of teams running option football, pure option. Now, we’re in shotgun-option. The game’s changed dramatically.” Another change Lombardi
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State, 572 S.W.2d 526 (Tex.Cr.App.1978). The convictions in Castillo, Hoaglund, and Weeks were affirmed in the absence of the statement of facts because those appellants failed to exercise due diligence in filing affidavits establishing indigency and the right to a free statement of facts. A comparison of those cases with the analysis adopted by the majority in Contreras and Mays suggests that, if the rule of diligence is applied to an indigent, the standard may differ from that articulated in Timmons as applicable to a non-indigent. The language of the Weeks opinion even states that, "it is incumbent upon a defendant to exercise due diligence to procure a transcription of the court reporter's notes by filing a pauper's oath." 521 S.W.2d at 862 [emphasis added]. The language of the statute makes no distinctions based on financial status, and certainly this court would not countenance an uneven application of the law. We conclude that the Timmons rule of diligence, a more recent decision than Weeks and supported by a long line of authority cited at 586 S.W.2d 512, is applicable to indigents and non-indigents alike. Accord: Wade v. State, 627 S.W.2d 777 (Tex.App.Waco 1981). In the instant case Appellant has demonstrated due diligence in establishing his indigency and requesting a statement of facts. The question remains whether the second prong of the rule of diligence articulated in Timmons is satisfied, i.e., has Appellant shown that the failure to file or have a statement of facts timely filed is not in any way due to negligence, laches, or other fault on the part of Appellant and his attorney? In our opinion a person of ordinary prudence would not delay 123 days after giving notice of appeal to contact the court reporter when the statute fixes responsibility upon the appellant to obtain the statement facts from the reporter and file it with the clerk not later than sixty days after notice of appeal. The record before us reflects no request for extension of time for filing the statement of facts. There is nothing in the record or even in Appellant's brief to suggest that counsel ascertained the identity of the court reporter or made any attempt whatsoever to contact the reporter prior to the expiration of the time for filing the statement of facts. In our opinion Appellant has not demonstrated that the unavailability of the requested statement of facts is not due to the negligence, laches, or other fault on the part of Appellant and his attorney. Therefore, Appellant is not entitled to reversal. In addition, we note that Appellant did not file with the clerk a designation of material for inclusion in the record but merely included in his affidavit of indigency a prayer for the court to direct the court reporter to 194 prepare a statement of facts. Tex.Code Crim.Pro.Ann. art. 40.09 § 2 (Vernon Supp. 1982) provides, in pertinent part, as follows: Each party may file with the clerk a written designation specifying matter for inclusion in the record. The appellant shall file his designation within 20 days after the giving notice of appeal.... The failure of the clerk to include designated matter will not be ground for complaint on appeal if the designation specifying such matter is not timely filed. [Emphasis added.] Furthermore, although the record lacks a statement of facts it reveals that Appellant entered a guilty plea and signed a stipulation of evidence establishing his guilt. When a plea of guilty is voluntarily and understandingly made, all non-jurisdictional defects including claimed deprivations of federal due process are waived. Helms v. State, 484 S.W.2d 925, 927 (Tex. Cr.App.1972); Galitz v. State, 617 S.W.2d 949, 952 (Tex.Cr.App.1981). We affirm. NOTES [1] Throughout this opinion we use the phrase "statement of facts" to mean a transcription of a court reporter's notes. In barber shops and beauty shops, customers often have their hair washed, dyed, curled, and provided with hair permanents, etc. as they lean backward in a chair with their neck resting on the edge of a sink. Typically, such a sink is of a special design having an indentation in its rim for receiving and supporting the neck of the customer. However, a hard sink rim can get quite uncomfortable for the customer over the long term as it presses against the neck and the back of the head, and can set off migraine headaches in some. By this invention a special pad is provided which greatly increases the comfort of the customer during treatment of the hair, while at the same time, the pad is very unlikely to slip out of its desired position in such an indentation of the sink rim.Q: Porting a MATLAB code to Python UPDATED TO REFLECT COMMENTS I am required to port a MATLAB code into python. Unfortunately, despite lot os sleepless nights of debugging and googling, I cannot get my code to run. Here is the MATLAB code in question: clc; serie =0:50; serie = serie - mean(serie); y = cumsum(serie); L = length(y); %Calculate the detrended fluctuation short term coefficient npuntos = 10; f1=zeros(1,npuntos); for n1=4:16 %Segmentation seg =(1:n1:L); %disp(length(seg)) yn = zeros(1,L); for k = 1:length(seg)-1 yaux = y(seg(k):seg(k+1)-1); x = 1:length(yaux); A=[sum(x.^2),sum(x); sum(x),length(x)]; C=[sum(x.yaux);sum(yaux)]; v=inv(A)C; a=v(1); b=v(2); pen=a; ord=b; ytrend = penx + ord; yn(seg(k):seg(k+1)-1) = ytrend'; end f1(n1) = sqrt((1/seg(end)).sum((y(1:seg(end)-1)-yn(1:seg(end)-1)).^2)); end n1=4:16; f1=f1(4:end); p1 = polyfit(log10(n1(1:end-2)),log10(f1(1:end-2)),1); alpha1 = p1(1); disp(alpha1) My attempt to translate the code into python goes as follows: import numpy as np data = np.arange(start=0, stop=51, step=1) data = data.transpose() data = data - np.mean(data) y = np.cumsum(data) L = len(y) # Estimate the value of alpha1 npuntos = 12 f1 = [0] npuntos for i, n1 in enumerate(np.arange(start=4, stop=16, step=1)): seg = np.arange(start=0, stop=L, step=n1) # Potential error yn = [0] * L for k in np.arange(start=0, stop=len(seg)-1, step=1): # Potential Error yaux = y[seg[k]:seg[k + 1]-1] # Potential Error x = np.arange(start=1, stop=len(yaux) + 1, step=1) A = [[sum(x ** 2), sum(x)], [sum(x), len(x)]] C = [[sum(x * yaux)], [sum(yaux)]] v = (np.linalg.inv(A)).dot(C) pen = v[0] ord = v[1] ytrend = pen * x + ord yn[seg[k]: seg[k + 1] - 1] = ytrend f1[i] = np.sqrt((1 / seg[-1]) * sum((y[1:seg[-1] - 1] - yn[1:seg[-1] - 1]) ** 2)) n1 =np.arange(start=4, stop=16, step=1) f1 = f1[4:] xx =np.log10(n1[1: - 2]) yy=np.log10(f1[1: - 2]) print(len(xx)) print(len(yy)) p1 = np.polyfit(xx, yy, 1) alpha1 = p1[1] print(alpha1) Unfortunately, I get TypeError when the program is executing this line p1 = np.polyfit(xx, yy, 1) This is indeed expected as xx is of length 9 while xx is just 5. By using try/catch block as suggested in the comment, try: f1[n1] = np.sqrt((1 / seg[-
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29, 5423, 1511, 568, 19057, 3, 187, 50255, 1590, 568, 5598, 2618, 3, 187, 50255, 2877, 43615, 10123, 15, 5598, 2618, 12377, 1138, 535, 50262, 29, 5423, 1511, 568, 19057, 3, 187, 50255, 1590, 568, 10495, 17986, 3, 187, 50255, 2877, 5473, 9819, 7509, 2618, 1381, 346, 6394, 10123, 15, 7509, 15, 301, 12377, 986, 16262, 187, 50266, 28683, 990, 6172, 23791, 535, 50266, 28683, 604, 10123, 15, 34590, 18658, 23791, 187, 50262, 29, 5423, 1511, 568, 19057, 3, 1318, 43615, 10123, 15, 34590, 18658, 15, 301, 12377, 3, 1416, 568, 301, 5647, 187, 50266, 28683, 27954, 23791, 535, 50266, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 23454, 23791, 187, 50262, 29, 2154, 966, 568, 630, 14, 736, 1138, 187, 50258, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 38203, 23791, 187, 50254, 29, 2154, 966, 568, 630, 14, 4399, 847, 14, 6535, 14, 21, 1885, 14, 20119, 14, 15337, 14, 630, 14, 38203, 1138, 187, 50254, 50274, 29, 1968, 323, 10817, 15337, 14, 630, 14, 38203, 1138, 187, 50254, 50270, 6394, 346, 20119, 15, 15337, 5232, 46464, 11495, 31899, 3675, 93, 2140, 64, 26125, 262, 907, 209, 5932, 92, 346, 16691, 15, 17354, 31899, 3675, 93, 2140, 64, 26125, 262, 907, 12377, 187, 50254, 50274, 870, 1968, 31, 535, 50254, 50274, 29, 2154, 2654, 568, 15337, 14, 630, 14, 38203, 3, 187, 50254, 50270, 966, 568, 7509, 14, 20119, 14, 15337, 14, 630, 14, 38203, 14, 5423, 3, 187, 50254, 50270, 941, 14, 38203, 14, 10394, 568, 5672, 1138, 187, 50254, 50270, 28683, 604, 941, 15, 788, 2073, 10801, 3401, 310, 417, 6325, 23791, 187, 50254, 50266, 28683, 873, 1655, 30183, 426, 941, 15, 788, 2073, 10801, 3401, 93, 9133, 64, 8124, 23791, 187, 50254, 50270, 28683, 2010, 23791, 187, 50254, 50266, 28683, 873, 1655, 30183, 426, 10123, 15, 6674, 15, 4090, 30183, 23791, 187, 50254, 50270, 28683, 27954, 23791, 535, 50254, 50270, 28683, 873, 2781, 30183, 426, 10123, 15, 6674, 15, 4090, 30183, 23791, 535, 50254, 50270, 28683, 323, 1127, 275, 337, 537, 4090, 30183, 23791, 187, 50254, 50266, 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6674, 23791, 187, 50254, 50266, 29, 81, 966, 568, 73, 23, 1885, 14, 20119, 14, 15337, 14, 630, 14, 38203, 14, 1156, 37183, 604, 1655, 30183, 3613, 4315, 15, 10801, 23791, 277, 14, 15422, 28683, 27954, 2462, 13272, 187, 50254, 245, 50265, 2203, 14, 38203, 14, 1156, 43615, 4315, 15, 10801, 12377, 1138, 187, 50254, 245, 50265, 12033, 346, 20119, 15, 15337, 4, 92, 6674, 15, 10801, 94, 8682, 46464, 4312, 31899, 3675, 93, 2140, 64, 26125, 262, 907, 12377, 187, 50254, 50266, 870, 81, 31, 187, 50254, 50270, 28683, 990, 1542, 23791, 187, 50254, 50274, 870, 2154, 31, 187, 50254, 870, 2154, 31, 187, 50258, 28683, 990, 6172, 23791, 535, 50258, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 5564, 23791, 187, 50254, 29, 2154, 966, 568, 630, 14, 4399, 847, 14, 805, 1885, 14, 20119, 14, 15337, 14, 630, 14, 5564, 1138, 187, 50254, 50274, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 5564, 64, 1968, 23791, 187, 50254, 50270, 29, 1968, 966, 568, 630, 14, 1968, 3, 323, 568, 15337, 13408, 1138, 187, 50254, 50266, 6394, 346, 20119, 15, 15337, 5232, 13408, 11495, 31899, 3675, 93, 2140, 64, 26125, 262, 907, 209, 5932, 92, 346, 16691, 15, 17354, 31899, 3675, 93, 2140, 64, 26125, 262, 907, 12377, 187, 50254, 50270, 870, 1968, 31, 187, 50254, 50274, 28683, 990, 6172, 23791, 535, 50254, 50274, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 5564, 64, 5423, 23791, 187, 50254, 50270, 29, 5423, 1511, 568, 1156, 3, 187, 50254, 245, 50265, 2437, 568, 630, 14, 8519, 28683, 604, 830, 55, 10966, 569, 15, 788, 55, 10966, 569, 28199, 5564, 3401, 23791, 310, 14, 25359, 28683, 27954, 2462, 13272, 187, 50254, 245, 50265, 301, 568, 15337, 13408, 3, 187, 50254, 245, 50265, 42152, 43615, 346, 20119, 15, 15337, 5232, 13408, 23495, 11375, 31899, 3675, 93, 296, 1122, 3544, 209, 5932, 92, 346, 16691, 15, 17354, 31899, 3675, 93, 296, 1122, 3544, 12377, 3, 187, 50254, 245, 50265, 1590, 568, 5564, 3, 187, 50254, 245, 50265, 2877, 43615, 941, 15, 788, 2073, 5564, 3401, 12377, 3, 187, 50254, 245, 50265, 17354, 568, 17354, 3, 187, 50254, 245, 50265, 1222, 3985, 568, 22, 1138, 187, 50254, 50274, 28683, 990, 6172, 23791, 535, 50254, 50274, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 5564, 64, 6584, 17888, 23791, 187, 50254, 50270, 28683, 604, 830, 55, 10966, 569, 15, 788, 55, 10966, 569, 28199, 5564, 3401, 310, 417, 6325, 23791, 187, 50254, 50266, 28683, 1863, 64, 3709, 37994, 15900, 6342, 16, 11869, 6342, 16, 307, 3191, 16, 630, 14, 6584, 17888, 15, 2974, 15, 7553, 304, 8, 342, 551, 187, 50254, 245, 50265, 8411, 5455, 27, 17882, 5564, 8, 187, 50254, 50266, 94, 23791, 187, 50254, 50270, 28683, 27954, 23791, 187, 50254, 50274, 28683, 990, 6172, 23791, 187, 50254, 870, 2154, 31, 187, 50258, 28683, 990, 6172, 23791, 187, 50262, 870, 2154, 31, 187, 50266, 28683, 990, 6172, 23791, 535, 50266, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 6071, 23791, 187, 50262, 29, 2154, 966, 568, 630, 14, 4399, 1885, 14, 20119, 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2073, 6071, 3401, 310, 417, 6325, 2462, 1217, 92, 941, 15, 788, 2073, 6071, 3401, 209, 5932, 6, 27954, 23791, 870, 44749, 31, 187, 50258, 28683, 990, 6172, 23791, 535, 50258, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 6071, 64, 6584, 17888, 23791, 187, 50254, 28683, 604, 830, 55, 10966, 569, 15, 788, 55, 10966, 569, 28199, 6071, 3401, 310, 417, 6325, 23791, 187, 50254, 50274, 28683, 1863, 64, 3709, 37994, 15900, 6342, 16, 11869, 6342, 16, 307, 3191, 16, 630, 14, 6584, 17888, 15, 2974, 15, 7553, 304, 8, 342, 551, 187, 50254, 50270, 6584, 17888, 5455, 27, 17882, 6071, 8, 187, 50254, 50274, 94, 23791, 187, 50254, 28683, 27954, 23791, 187, 50258, 28683, 990, 6172, 23791, 187, 50262, 870, 2154, 31, 187, 50266, 28683, 990, 6172, 23791, 535, 50266, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 28497, 23791, 187, 50262, 29, 2154, 966, 568, 7509, 14, 20119, 14, 15337, 14, 630, 14, 28497, 1138, 187, 50258, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 17354, 23791, 187, 50254, 29, 81, 966, 568, 17354, 14, 15069, 1138, 187, 50254, 50274, 6394, 346, 16691, 15, 17354, 24306, 31899, 3675, 93, 2140, 64, 26125, 262, 907, 12377, 187, 50254, 870, 81, 31, 187, 50258, 28683, 990, 6172, 23791, 535, 50258, 29, 2154, 966, 568, 7509, 14, 20119, 14, 15337, 14, 630, 14, 3518, 1138, 187, 50254, 28683, 2972, 3239, 64, 7509, 64, 20119, 64, 15337, 64, 630, 64, 35899, 23791, 187, 50254, 50274, 29, 66, 3860, 10817, 3, 187, 50254, 50272, 966, 568, 15581, 23929, 14, 483, 1282, 14, 36277, 1885, 14, 20119, 14, 15337, 14, 35899 ]	is the equal sharing of misery. - Sir Winston Churchill Americans love to fight. All real Americans love the sting of battle. - General George S. Patton Sr. The damage in that game is waaaaaay off. But it will get fixed. Unlike cod, the BF developers actually care what people think. +1. CoD developers just care about hacking. Battlefield has always been a top notch game, CoD is just good for a week then it gets boring. __________________ Socialism is a philosophy of failure, the creed of ignorance, and the gospel of envy, its inherent virtue is the equal sharing of misery. - Sir Winston Churchill Americans love to fight. All real Americans love the sting of battle. - General George S. Patton Sr. Here's my major issue, They shut down the beta because they threw a hussy fit over the feedback. Then they turn around and sell the beta for full price. I'm tired of hearing "it's a known issue and we are working on it". Here's my major issue, They shut down the beta because they threw a hussy fit over the feedback. Then they turn around and sell the beta for full price. I'm tired of hearing "it's a known issue and we are working on it".{% block page_product_detail_review_form %} {% if data is not defined and reviews.customerReview is defined %} {% set data = reviews.customerReview %} {% endif %} {% set formAjaxSubmitOptions = { replaceSelectors: '.js-review-container' } %} {% block page_product_detail_review_form_form %} <form class="review-form" action="{{ path('frontend.detail.review.save', { productId: reviews.productId }) }}" method="post" data-form-validation="true" data-form-ajax-submit="true" data-form-ajax-submit-options='{{ formAjaxSubmitOptions\|json_encode }}'> {% block page_product_detail_review_form_csrf %} {{ sw_csrf('frontend.detail.review.save') }} {% endblock %} {% block page_product_detail_review_form_forward %} <input type="hidden" name="forwardTo" value="frontend.product.reviews"> <input type="hidden" name="parentId" value="{{ reviews.parentId }}"> <input type="hidden" name="forwardParameters" value='{"productId": "{{ reviews.product.id }}"}'> {% endblock %} {% if reviews.customerReview %} <input type="hidden" value="{{ reviews.customerReview.id }}" name="id"/> {% endif %} {% block page_product_detail_review_form_details %} <div class="form-row"> {% block page_product_detail_review_form_rating %} <div class="form-group col-md-4 product-detail-review-form-rating"> <label for="#review-form-rating"> {{ "detail.reviewFormRatingLabel"\|trans\|sw_sanitize }}{{ "general.required"\|trans\|sw_sanitize }} </label> <div id="review-form-rating" class="product-detail-review-form-rating-input" data-rating-system="true"> {% if data.get('points') is not empty %} {% set currentPoints = data.get('points')\|number_format %} {% else %} {% set currentPoints = reviews.matrix.maxPoints %} {% endif %} {% set maxPoints = reviews.matrix.maxPoints %} {% for point in 1..maxPoints %} <label data-review-form-point="{{ point }}" class="product-detail-review-form-star{% if currentPoints >= point %} is-active{% endif %}"> <input class="product-detail-review-form-radio" type="radio" name="points" value="{{ point }}" {% if currentPoints >= point %} checked="checked"{% endif %}> {% sw_include '@Storefront/storefront/component/review/point.html.twig' with { type: 'blank' } %} </label> {% endfor %} {% for matrix in reviews.matrix.matrix %} <p class="h6 product-detail-review-form-rating-text {% if currentPoints!= matrix.points %} d-none{% endif %}" data-rating-text="{{ matrix.points }}"> {{ "detail.review#{matrix.points}PointRatingText"\|trans\|sw_sanitize }} </p> {% endfor %} </div> </div> {% endblock %} {% block page_product_detail_review_form_title %} <div class="form-group col-12 product-detail-review-form-title"> {% block page_product_detail_review_form_title_label %} <label class="form-label" for="reviewTitle"> {{ "detail.reviewFormTitleLabel"\|trans\|sw_sanitize }}{{ "general.required"\|trans\|sw_sanitize }} </label> {% endblock %} {% block page_product_detail_review_form_title_input %} <input type="text" class="form-control{% if formViolations.getViolations('/title') %} is-invalid{% endif %}" id="reviewTitle" placeholder="{{ "detail.reviewFormTitlePlaceholder"\|trans\|striptags }}{{ "general.required"\|trans\|striptags }}" name="title" value="{{ data.get('title') }}" required="required" minlength="5"> {% endblock %} {% block page_product_detail_review_form_title_violation %} {% if formViolations.getViolations('/title') is not empty %} {% sw_include '@Storefront/storefront/utilities/form-violation.html.twig' with { violationPath: '/title' } %} {% endif %} {% endblock %} </div> {% endblock %} </div> {% endblock %} {% block page_product_detail_review_form_content %} <div class="form-group product-detail-review-form-content"> {% block page_product_detail_review_form_content_label %} <label for="reviewContent"> {{ "detail.reviewFormContentLabel"\|trans\|sw_sanitize }}{{ "general.required"\|trans\|sw_sanitize }} </label> {% endblock %} {% block page_product_detail_review_form_content_textarea %} <textarea class="form-control{% if formViolations.getViolations('/content') %} is-invalid{% endif %}" id="reviewContent" name="content" required="required" minlength="40" rows="8">{% if data.get('content') is not empty %}{{ data.get('content') }}{% endif %}</textarea> {% endblock %} {% block page_product_detail_review_form_content_violation %} {% if formViolations.getViolations('/content') is not empty %} {% sw_include '@Storefront/storefront/utilities/form-violation.html.twig' with { violationPath: '/content' } %} {% endif %} {% endblock %} </div> {% endblock %} {% block page_product_detail_review_form_footer %} <div class="product-detail-review-form-footer"> {% block page_product_detail_review_form_required %} <p class="required-fields"> {{ "general.requiredFields"\|trans\|sw_sanitize }} </p> {% endblock %} <div class="product-detail-review-form-actions"> {% block page_product_detail_review_form_cancel %} <a href="#" class="btn btn-outline-secondary product-detail-review-cancel
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1340, 15, 1198, 436, 13, 359, 452, 908, 253, 6422, 2685, 5150, 2746, 534, 310, 247, 8967, 2715, 273, 10520, 457, 84, 39358, 1387, 9261, 15, 496, 9433, 436, 1332, 13, 359, 452, 2326, 326, 19124, 2426, 275, 253, 10520, 757, 3576, 26150, 313, 4609, 556, 247, 6486, 12160, 23046, 669, 2293, 45, 30, 46, 1366, 247, 8847, 4311, 9999, 5536, 14, 25268, 26682, 10, 403, 8171, 494, 407, 253, 3969, 2169, 15759, 8212, 9158, 5043, 4828, 27169, 323, 616, 3580, 275, 253, 19106, 2701, 313, 2811, 12160, 23046, 310, 6326, 281, 564, 281, 23579, 481, 380, 6158, 476, 320, 18445, 342, 342, 253, 1361, 273, 253, 2622, 1885, 4473, 15, 7243, 436, 958, 310, 8344, 13, 39401, 310, 15246, 27, 512, 370, 18, 16, 46, 768, 19, 47, 15728, 2621, 2538, 476, 320, 7011, 275, 2426, 273, 1980, 13388, 7668, 9158, 273, 7877, 3019, 21, 12, 19, 47, 3822, 1707, 1615, 359, 12666, 387, 247, 1980, 19106, 3576, 1673, 3762, 534, 8631, 1698, 14, 14115, 1708, 14, 25268, 12057, 13613, 598, 281, 667, 6799, 1340, 275, 370, 18, 16, 46, 63, 19, 5, 342, 4569, 10272, 4803, 323, 19124, 313, 4160, 445, 1939, 12729, 10, 13388, 15, 3932, 253, 7125, 1060, 403, 9093, 15759, 285, 8127, 3762, 14, 17777, 13, 352, 943, 417, 320, 2834, 281, 39970, 731, 281, 1027, 1673, 11813, 824, 347, 11206, 11813, 390, 11813, 342, 17046, 10377, 10155, 15, 8079, 13, 34430, 4906, 369, 8058, 323, 841, 11813, 275, 1008, 72, 343, 472, 6646, 62, 1561, 436, 2746, 15, 187, 187, 7542, 253, 27654, 323, 3576, 1980, 13388, 3831, 9136, 273, 669, 2808, 187, 9, 46, 16, 78, 1009, 275, 20452, 3762, 13, 352, 310, 2223, 11408, 281, 2020, 824, 21953, 334, 983, 275, 247, 12082, 1039, 15, 831, 556, 644, 6786, 407, 17617, 247, 873, 273, 5520, 9368, 266, 14, 23875, 11670, 1479, 7424, 1008, 2148, 70, 1570, 5220, 13, 1060, 359, 3710, 776, 4116, 281, 11302, 3470, 387, 10254, 2491, 669, 78, 30, 48, 9, 78, 3822, 1284, 581, 5459, 669, 78, 5, 281, 10481, 1029, 2341, 4311, 13, 253, 9722, 78, 16, 78, 16550, 39606, 359, 22459, 588, 2489, 1774, 15, 46769, 824, 669, 78, 2911, 39606, 285, 14631, 14493, 625, 9257, 13, 581, 778, 1263, 253, 1029, 14, 42647, 3879, 273, 6115, 3470, 313, 9154, 275, 253, 18714, 10254, 2919, 10, 1561, 253, 3576, 1673, 3762, 3634, 15, 831, 3033, 556, 644, 2797, 275, 1008, 2910, 19, 62, 323, 1182, 254, 837, 1340, 3576, 3762, 313, 47771, 281, 34430, 4906, 481, 187, 187, 688, 6010, 13, 253, 2685, 5150, 13, 534, 310, 1754, 327, 10520, 757, 31460, 273, 3576, 3762, 13, 3400, 2590, 4685, 273, 3576, 11813, 275, 19106, 15, 187, 187, 1147, 310, 619, 1270, 11284, 281, 5717, 21001, 15, 399, 15, 575, 49, 15, 575, 10292, 323, 31337, 479, 281, 253, 5768, 2143, 15, 831, 789, 369, 4516, 275, 629, 407, 9733, 6875, 285, 17388, 6807, 949, 12938, 36, 2086, 15, 187, 187, 60, 1525, 1181, 611, 15, 443, 15, 10520, 13, 544, 9083, 15, 575, 7498, 15, 575, 13811, 60, 35, 21, 1181, 7444, 1181, 313, 25197, 10, 495, 18804, 13, 495, 19105, 28, 611, 15, 443, 15, 10520, 285, 500, 15, 575, 44, 462, 307, 13, 4111, 15, 575, 6802, 15, 575, 13811, 805, 7444, 313, 22062, 10, 6879, 15, 2594, 13, 323, 1650, 13, 611, 15, 443, 15, 10520, 13, 3555, 15, 575, 4120, 15, 575, 9083, 15, 575, 13811, 2417, 7444, 313, 16460, 10, 608, 3245, 15, 500, 15, 3130, 348, 26630, 13, 544, 47, 13340, 15, 575, 9083, 15, 575, 13811, 60, 35, 18390, 1181, 7444, 1181, 313, 15624, 10, 28534, 15, 443, 15, 44172, 13, 330, 15, 21009, 3803, 285, 353, 15, 6470, 33928, 1171, 254, 13, 7518, 87, 15, 4111, 15, 3162, 66, 4299, 2082, 7444, 313, 13895, 10, 4567, 28, 443, 15, 44172, 285, 330, 15, 21009, 3803, 13, 544, 9083, 15, 575, 21457, 15, 575, 13811, 60, 25671, 1181, 7444, 1181, 313, 14209, 10, 32597, 15, 378, 15, 500, 15, 411, 3298, 13, 544, 20339, 15, 575, 9083, 15, 313, 47, 15, 714, 2698, 575, 13811, 60, 21092, 1181, 7444, 1181, 313, 14619, 10, 337, 13, 11289, 15, 330, 15, 575, 35, 886, 4635, 13, 275, 3921, 38, 3695, 3512, 3741, 13, 7327, 380, 2370, 285, 18300, 27376, 982, 11661, 313, 46, 15, 575, 27157, 5391, 13, 443, 15, 575, 9709, 2706, 5391, 285, 444, 15, 575, 2374, 1171, 363, 444, 1397, 10, 2956, 785, 2499, 13, 9725, 15, 26177, 7589, 10766, 13, 544, 20339, 15, 575, 9083, 15, 313, 47, 15, 714, 2698, 575, 13811, 60, 23525, 1181, 7444, 1181, 313, 12731, 10, 12387, 313, 14341, 14, 394, 16, 26, 24948, 12231, 481, 500, 15, 575, 35, 1326, 265, 13, 275, 436, 4644, 15, 330, 15, 411, 466, 68, 8260, 45593, 13, 544, 25600, 15, 575, 18102, 15, 575, 9083, 15, 575, 13811, 60, 8193, 1181, 7444, 1181, 313, 14619, 10, 20995, 28, 443, 15, 44172, 13, 7518, 87, 15, 4111, 15, 3162, 66, 4299, 2526, 7444, 313, 13549, 10, 42955, 15, 500, 15, 24008, 285, 500, 15, 24472, 13, 544, 47, 13340, 15, 575, 9083, 15, 575, 13811, 60, 35, 20664, 1181, 7444, 1181, 313, 14619, 10, 26235, 15, 443, 15, 44172, 285, 330, 15, 21009, 3803, 13, 544, 25600, 15, 575, 18102, 15, 575, 9083, 15, 575, 13811, 60, 16989, 1181, 7444, 1181, 313, 13895, 10, 38848, 28, 4299, 16271, 7444, 313, 13549, 10, 22752, 15, 416, 15, 575, 37, 15, 575, 38404, 13, 367, 15, 575, 38, 15, 575, 18853, 356, 19434, 13, 500, 15, 575, 42, 15, 575, 45, 1080, 250, 13, 285, 444, 15, 575, 7673, 2369, 13, 544, 9083, 15, 575, 21457, 15, 575, 13811, 60, 35, 23568, 1181, 7444, 1181, 313, 12731, 10, 5096, 15, 308, 15, 575, 51, 15, 575, 18968, 4448, 13, 14618, 14, 394, 16, 35366, 938, 1867, 285, 23378, 15308, 15, 353, 15, 575, 1785, 18696, 285, 330, 15, 575, 56, 46467, 469, 13, 544, 47, 13340, 15, 575, 9083, 15, 575, 13811, 60, 35, 39069, 1181, 7444, 1181, 313, 13034, 10, 26240, 285, 10414, 15308, 15, 530, 15, 575, 28578, 88, 3751, 544, 9083, 15, 575, 21457, 15, 575, 13811, 60, 35, 22519, 1181, 7444, 1181, 313, 13034, 10, 35585, 15, 353, 15, 575, 37, 457, 6601, 24288, 900, 285, 308, 15, 575, 51, 15, 575, 18968, 4448, 13, 544, 9083, 15, 575, 21457, 15, 575, 13811, 60, 35, 25139, 1181, 7444, 1181, 313, 12487, 10, 25098, 15, 330, 15, 575, 56, 46467, 469, 13, 544, 9083, 15, 575, 21457, 15, 575, 13811, 60, 35, 17615, 1181, 7444, 1181, 313, 13549, 10, 5091, 15, 399, 15, 575, 54, 15, 575, 43, 1947, 781, 293, 285, 330, 15, 575, 56, 46467, 469, 13, 14618, 14, 545, 16, 4148, 740, 26933, 285, 10414, 15308, 15, 308, 15, 575, 38, 15, 575, 2019, 782, 13, 378, 15, 575, 18853, 25933, 285, 322, 15, 575, 53, 15, 575, 23337, 544, 47, 13340, 15, 575, 9083, 15, 575, 13811, 60, 35, 24948, 1181, 7444, 1181, 313, 13549, 10, 721, 1619, 15, 353, 15, 11228, 5391, 13, 353, 15, 399, 457, 6601, 29496, 900, 285, 443, 15, 2398, 2706, 5391, 13, 544, 47, 13340, 15, 575, 9083, 15, 575, 13811, 60, 35, 24264, 1181, 7444, 1181, 313, 13549, 10, 40657, 28, 4299, 35, 35833, 7444, 313, 13034, 10, 11681, 28, 544, 9083, 15, 575, 21457, 15, 575, 13811, 60, 22011, 1181, 7444, 1181, 313, 13034, 10, 29503, 15, 308, 15, 575, 51, 15, 575, 18968, 4448, 13, 544, 4807, 15, 575, 43, 15, 575, 4120, 15, 575, 9083, 15, 575, 13811, 60, 34, 26, 1181, 7444, 1181, 313, 13034, 10, 2164, 883, 15, 401, 15, 575, 43 ]	&=&[S\_[int]{}\^[[[\_0]{}]{};N\_0-1]{}]{}+ \_i\[Ø\_i\^[(4+2N\_0)]{}\] +S\^[[[\_0]{}]{};N\_0]{}\_[CT]{}, where $a_i^{(4+2N)}$’s are appropriate linear combinations of $b_{2n,\{w\}}^{R;N}$’s (all of which are $O(1/M^{2N})$). Thus the $1/M^{2N}$-order information of the full theory is factorized into the coefficient $a_i^{(4+2N)}$’s of local vertices of dimension $(4+2N)$. If we want to increase the accuracy from $O(1/M^{2N_0})$ to $O(1/M^{2(N_0+1)})$, we have only to include in ${\widetilde S_{int}^{{{\Lambda_0}};N_0}}$ local vertices $[\O_i^{(4+2(N_0+1))}]$ of dimension $4+2(N_0+1)$. (The lower dimensional vertices need not be modified.) The coefficients $a_i^{4+2(N_0+1)}$ are calculable as the difference of appropriate Green functions of the full theory and those of the effective theory (i.e., ${\widetilde S_{int}^{{{\Lambda_0}};N_0}}$) at renormalization point. New divergences are subtracted away by $S^{{{\Lambda_0}};N_0+1}_{CT}$. Given this bare Lagrangian, the flow equation guarantees that all Green functions are finite and accurate up to order $1/M^{2(N_0+1)}$. The interpretation of this result is clear from the viewpoint of the renormalization group flow in the infinite dimensional space of possible Lagrangians. As we reduce the cutoff, the bare Lagrangian of the full theory, which is specified by the boundary conditions (\[fbc\]) and (\[fbc2\]), flows down to a submanifold parametrized by relevant couplings only. It has both heavy and light operators. Now the flow may be projected onto the subspace of operators consisting of the light field only. Then finding a local low-energy effective field theory of light particles is equivalent to finding a renormalization group flow with a few (relevant or irrelevant) local operators which can best approximate the projected flow of the full theory. To the zeroth order in $1/M^2$, it is done with relevant terms only by choosing the same renormalization conditions as those of the full theory. The deviation from the full-theory flow is corrected by reading off values of the remaining irrelevant coordinates at the $\LLL=0$ point. At first, components of dimension six operators may be read, which tell us the effects of order $1/M^2$; the flow of the full theory is now approximated to the order $1/M^2$ at $\LLL<M$. If one wants to increase the accuracy, it is necessary to read more and more irrelevant coordinates (at $\LLL=0$) of the projected flow of the full theory and modify the effective-theory flow with the corresponding flow equation given in Eq. (\[flowk\]). Our equation (\[flowk\]) automatically takes care of possible divergences due to the unnaturally large irrelevant components in such a way that the bare Lagrangian may contain only a finite number of irrelevant terms. Conclusions =========== In the context of a simple scalar field theory, we have demonstrated that, at low energy, virtual heavy particle effects on light-particle Green functions are completely factorized via effective local vertices to any desired order. For this, we have used the powerful flow equation approach which is a differential version of Wilson’s renormalization group transformation. In applying this method, we have seen that irrelevant terms in the Wilsonian effective Lagrangian (which has a finite UV cutoff $\LLL=M$, a characteristic scale representing heavy-particle thresholds) are replaceable by the corresponding higher dimensional composite operators plus counterterms for their products in the continuum limit (where UV cutoff is supposed to go to infinity). The latter can be dealt with with the help of the normal product concept. Once this fact is noticed, factorization is straightforward: all $1/M^{2N}$-order effects can be isolated in terms of local vertices involving operators of dimension $(4+2N)$. Thereby we arrive at a local continuum effective field theory which describes low-energy light-particle physics accurately up to any desired order in $1/M^2$ with appropriate calculation rules for irrelevant (nonrenormalizable) vertices. Since the arguments here are essentially dimensional and largely theory-independent, it should not be difficult to generalize them to different field theories such as gauge theories or theories with spontaneous symmetry breaking. Indeed, decoupling was proved for these theories in [@girardello] within this approach. Since the couplings for effective local vertices contain powers of $\log (M/m)$ in perturbation theory, it is often desirable to sum such logarithms in a systematic way. This has been achieved by utilizing a set of improved Callan-Symanzik equations [@clee]. Also, here we limited our attention to vertex functions at momentum range $\m=O(m)$. As one increases $\m$ to sufficiently high energy scale, the $(\m/m)$-dependence we neglected will become important. Keeping such $\m$-dependence and establishing bounds more carefully, one may study the high-momentum behavior of Green functions (even in the exceptional momentum region) within the effective field theory context. This bound has been obtained in [@ball2] for zeroth order effective theory (corresponding to decoupling). In summary, the flow equation, which is based on Wilsonian viewpoint of effective theory, provides clear understanding of effective theories in continuum. It is my great pleasure to thank Prof. D. P. Min for inviting me to the summer school. This work was supported in part by Korea Science and Engineering Foundation through SRC program. [99]{} K. G. Wilson, [Phys. Rev. [[B4]{}]{}]{} (1971) 3174, 3184; K. G. Wilson and J. Kogut, Phys. Rep. [12]{} (1974) 75. See, for example, K. G. Wilson, Rev. Mod. Phys. [55]{} (1983) 583. J. Polchinski, [Nucl. Phys. [[B231]{}]{}]{} (1984) 269. G. Keller, C. Kopper and M. Salmhofer, Helv. Phys. Acta [65]{} (1992) 32; G. Keller and C. Kopper, [Phys. Lett. [[273]{}]{}]{} (1991) 323. B. J. Warr, [Ann. Phys. (N. Y.) [[183]{}]{}]{} (1988) 1, 89. C. Becchi, in [Elementary Particles, Field Theories and Statistical Mechanics]{}, (M. Bonini, G. Marchesini and E. Onofri Eds) Parma University, 1993. Chanju Kim, [Ann. Phys. (N. Y.) [[243]{}]{}]{} (1995) 117 (hep-th/9402117). J. Berges, in this volume. C. Wieczerkowski, [Comm. Math. Phys. [[120]{}]{}]{} (1988) 148; G. Keller, Helv. Phys. Acta [66]{} (1993) 453. J. Hughes and J. Liu, [Nucl. Phys. [[B161]{}]{}]{} (1988) 183. G. Keller and C. Kopper, [Comm. Math. Phys. [[148]{}]{}]{} (1992) 445; [153]{} (1993) 245. R. D. Ball, P. E. Haagensen, J. I. Latorre, and E. Moreno, [Phys. Lett. [[B347]{}]{}]{} (1995) 80. T. R. Morris, hep-th/9802039 and referenced therein. M. Reuter and C. Wetterich, [Nucl. Phys. [[B417]{}]{}]{} (1994) 181 and references therein. U. Ellwanger [Phys. Lett. [[B335]{}]{}]{} (1994) 364. M. D’Attanasio and T. R. Morris, [Phys. Lett. [[B378]{}]{}]{} (1996) 213. C. Wetterich, [Phys. Lett. [[B301]{}]{}]{} (1993) 90. D. U. Jungickel and C. Wetterich, hep-ph/9710397 and references therein. T. E. Clark, B. Haeri and S. T. Love [Nucl. Phys. [[B402]{}]{}]{} (1993) 628. M. Bonini, M. D’Attanosio and G. Marchesini, [Nucl. Phys. [[B409]{}]{}]{} (1993) 441; [B418]{} (1994) 81; [Phys. Lett. [[329]{}]{}]{} (1994) 249. T. R. Morris, [Int. J. Mod. Phys. [[A9]{}]{}]{} (1994) 2411. F. J
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30747, 1794, 10364, 8927, 432, 14307, 285, 1024, 3811, 275, 22699, 25681, 15, 1284, 344, 8631, 352, 13, 346, 42, 574, 281, 806, 3368, 285, 1611, 436, 13612, 387, 1728, 15, 733, 310, 17319, 2, 3366, 16107, 247, 6196, 2739, 323, 21896, 2801, 15, 309, 5476, 359, 476, 1067, 352, 686, 35, 518, 77, 2623, 32592, 8, 390, 686, 11592, 14, 3243, 25958, 77, 2623, 18574, 64, 187, 187, 64, 8497, 27, 3723, 22267, 10777, 313, 4064, 3723, 22267, 18324, 13, 285, 294, 19280, 281, 320, 253, 954, 8530, 275, 14307, 13, 310, 5480, 342, 1824, 14664, 12584, 8463, 10, 588, 564, 327, 1755, 273, 253, 35246, 77, 2623, 1078, 9417, 15, 380, 806, 3924, 273, 436, 13612, 3198, 281, 2826, 5540, 1253, 2385, 3038, 1078, 9417, 3333, 187, 187, 22521, 1992, 2784, 17906, 187, 187, 93, 187, 187, 20782, 187, 187, 18, 2805, 85, 5536, 10777, 187, 187, 93, 187, 187, 22521, 52, 6147, 484, 17906, 187, 187, 93, 187, 187, 8313, 330, 13735, 33620, 297, 14795, 1040, 495, 330, 1824, 187, 187, 19, 8313, 330, 8618, 1040, 337, 246, 18616, 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8618, 13, 285, 1824, 28, 3324, 281, 247, 22149, 285, 1339, 32469, 323, 1884, 1253, 1449, 2909, 15, 5733, 18616, 14709, 15, 22347, 15, 20004, 667, 22441, 390, 8954, 394, 326, 778, 3176, 327, 253, 2553, 342, 247, 26531, 390, 9931, 282, 15, 28593, 436, 14795, 14, 84, 16734, 30121, 281, 4484, 281, 2316, 3276, 327, 253, 8576, 4828, 15, 187, 187, 64, 1992, 1056, 253, 12868, 23338, 22679, 374, 1253, 20, 330, 8135, 264, 10250, 8712, 37999, 15, 3774, 1225, 253, 10250, 33507, 281, 247, 10115, 4187, 830 ]	brown sugar, flour, and egg until blended. Press evenly into 15 by 10 by ¾-inch jelly-roll pan. Bake at 350 degrees for 15 minutes. For filling, sprinkle pecan halves evenly over crust. In large, heavy saucepan melt butter; add honey and brown sugar; stir to dissolve. Bring mixture to a boil over medium high heat and let boil for 5–7 minutes, or until mixture reaches a rich caramel color. Remove from heat and stir in whipping cream. Combine thoroughly. Pour caramel mixture over pecans. Bake at 350 degrees for 15 minutes, or until done; cool. YIELDS 4 DOZEN BARS. ### Almond-Fruit Diamonds _The "favorite cookie for 1980":_ Crust \| ---\|--- 3 C flour \| 1 C sugar, divided 1/8 t salt \| 2 eggs 1½ C butter, divided \| ½ t grated lemon peel _Topping_ \| ½ C honey \| 1 C sliced almonds 2 T heavy cream \| ¾ C red and green candied cherries 1 t vanilla \| Preheat oven to 350 degrees. Adjust oven rack to lower third of oven. Grease 15½ by 10½-inch jelly-roll pan. Combine flour and salt in large bowl. Beat 1C butter and ½ C sugar in large mixing bowl at medium speed. Beat in eggs and lemon peel until mixture is light and fluffy. Gradually beat in dry ingredients. Press dough evenly into prepared pan, making a ¼-inch high rim. Bake 25–30 minutes until top is lightly brown and dough is firm to the touch. Five minutes before crust is done, melt remaining ½ C butter in saucepan, add honey, remaining ½ C sugar, cream, and vanilla. Heat to boiling, then boil, stirring for 5 minutes. Stir in almonds and fruit. Pour over crust. Bake 10 minutes more. Cool. Cut into 2 by 1¼-inch diamonds. YIELDS 52 COOKIES. _Source:_ Personal notebooks of Hermilda Listeman. ### Honey Lemon-Slice Cookie Bars 1 C brown sugar, firmly packed \| 1 C pure honey ---\|--- 2 C sifted flour \| ¼ C lemon juice ½ C butter + 2 T \| 3 eggs, beaten unmercifully 1 C shredded or flaked coconut \| Blend together brown sugar, flour, butter, and coconut. Pat of mixture into an ungreased 9-inch square pan. In small saucepan, cook together honey, 2 T butter, lemon juice, and eggs, stirring constantly until mixture thickens. Cool and spread over coconut mixture in pan. Sprinkle remainder of coconut mixture over top. Bake at 350 degrees for 40 minutes. Cut in 1½-inch squares and cool in pan or rack. YIELDS 3 DOZEN BARS. _Source:_ Personal notebooks of Hermilda Listeman, with the note "from the Gourmet Co-op." ### Honey Nut Brownies _Note: If the brownies will be eaten immediately, use a combination of ½ C honey and ½ C brown sugar._ ¼ C butter \| ½ C flour ---\|--- 2 oz bitter chocolate \| ½ t baking powder 1 C honey \| 1 C chopped nuts 2 eggs, beaten \| Melt butter and chocolate together, then stir in honey (see Note). Add eggs and stir to combine well. Sift flour and baking powder and stir into chocolate mixture. Add nuts. Bake at 300 degrees for 45 minutes. Pack brownies away in jar or bread box. Before serving, cut in strips about ½-inch wide and 2 inches long. Roll in powdered sugar if desired. _Source:_ Adapted from Vern Milum, University of Illinois Extension Service mimeographed bulletin, 1929. ### First-Prize Honey Date Bars _This recipe was a prizewinner at the 1934 Illinois State Fair Honey Culinary Competition. The recipes for that event were published without attribution and often (as in the case of this recipe) without instructions. A handwritten note on the recipe indicates that "second and third prizes were Kellogs [_ sic _] Honey Date Bars."_ 2 eggs \| ¼ t salt ---\|--- ¼ C honey \| ½ T baking powder ¼ C sugar \| 1¼ C dates, chopped C flour \| ¾ C nuts, chopped Beat eggs well and mix in honey and sugar. Sift flour with salt and baking powder and add to egg mixture. Stir in dates and nuts. Spread in a greased 11 by 15-inch jelly-roll pan. Bake at 350 degrees for 15–25 minutes. Cut into strips ½ inch wide and 3 inches long. _Source:_ Adapted from the _Annual Report of the Illinois State Beekeepers Association_, 1934. ### Apricot Bars ½ C butter \| 1 t salt ---\|--- 1½ C brown sugar, packed \| 1 t baking powder ½ C honey \| 1 t cinnamon zest of 1 lemon \| 6 oz dried apricots, chopped 3 eggs \| 1 C chopped or slivered almonds 1¾ C flour \| \| _Lemon Glaze_ \| \| ¾ C powdered sugar \| 1 T lemon juice Cream butter, sugar, honey, and lemon zest; beat in eggs. In a separate bowl, combine dry ingredients. Mix into creamed mixture and stir until thoroughly blended. Fold in almonds and apricots. Spread into 15 by 10 by 1-inch baking pan and bake at 350 degrees for 20–25 minutes. Cut into bars. To make the glaze, mix sifted powdered sugar with lemon juice. Pour over cooled bars. YIELDS ABOUT 50 BARS. ### Beehives _A recipe translated by Martin Hauser, a Ph.D. graduate in entomology at the University of Illinois at Urbana-Champaign and originally from Germany._ ½ C butter \| 1 t cinnamon ---\|--- 1 egg yolk \| 8 T rose-hip jam 4 T honey \| a few drops of lemon juice C sugar \| 1 package agar-agar powder ½ C ground hazelnuts \| powdered sugar for decoration 1 C flour \| Mix butter, egg yolk, 1 T honey, sugar, nuts, flour, and cinnamon; refrigerate for 45 minutes. Roll dough flat (about ¼ inch thick) and cut 20 rounds approximately 1¾ inches in diameter, and 10 rounds a little more than an inch in diameter. Make hollow rings by cutting the centers out of all the small disks and 10 of the large disks. Place dough on baking paper. Bake at 350 degrees for 18 minutes. While dough is baking, mix the remaining honey, rose-hip jam, and lemon juice with the agar-agar powder. To assemble beehives, use a large disk for the bottom, and stack with rings. Fill the centers with the honey mixture; decorate with powdered sugar. YIELDS APPROXIMATELY 10 BEEHIVES. ### Really Rich Baklava _This recipe comes from Tugrul Giray, a University of Illinois at Urbana-Champaign bee biologist originally from Turkey and now living in Puerto Rico. As he describes it, "I had to first experiment and try this recipe at home. It is delicious! Definitely a diet food for gaining weight. I guess we can call it 'Baklava Heavy' or 'Non-light Baklava.'"_ _Note: Afyon cream (from Afyon Province, and reputed to be the most famous in Turkey, is prepared with water buffalo milk) will go on top of the baklava before serving. The first stage of this recipe needs to occur 36–48 hours before serving._ _Topping_ \| ---\|--- 1 qt heavy cream \| _Syrup_ \| ½ C orange blossom honey \| 3 C water 2½ C sugar \| 1 t lemon juice _Filling_ \| 2–3 C walnut halves \| ½ t cinnamon (optional) 1 T flavorful honey \| _Pastry_ \| 1-lb package phyllo sheets \| 1 stick butter (or more as needed) Simmer heavy cream in a wide container (a deep stainless-steel pan is preferable) on low heat, stirring more or less continuously for 1 hour. Pour the thickened heavy cream in a tray (about inch thick). Let cool to room temperature, cover with a layer of plastic wrap or waxed paper to prevent oxidation or color change, and refrigerate for 36–48 hours until it is solid and can be cut with a butter knife and served with a spatula. _To make the syrup:_ Mix orange blossom honey, sugar, and water; bring to a boil and let simmer for 30–40 minutes. Add lemon juice. Mix. Remove any foam or froth that may appear on the surface with a spoon or ladle. Leave this honey-sugar syrup to cool to room temperature on the kitchen counter. _To make the filling:_ Measure 2–3 C shelled walnut halves. Smash the walnuts to a granulate form
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1840, 285, 2708, 253, 12998, 403, 253, 1543, 273, 13993, 285, 11356, 28551, 6260, 13, 2975, 15, 7214, 28551, 2193, 12667, 3925, 6, 403, 2011, 15, 380, 5026, 12998, 5224, 12667, 470, 15, 2222, 12637, 5912, 432, 26812, 17032, 15, 25474, 16095, 403, 14495, 281, 253, 1180, 273, 35225, 591, 2670, 313, 2887, 253, 4311, 2534, 481, 5642, 6492, 5937, 267, 306, 311, 684, 15, 380, 1416, 273, 253, 34710, 2601, 14, 27676, 3320, 326, 556, 644, 5421, 21657, 905, 2537, 696, 310, 1677, 275, 26609, 15, 9350, 380, 1899, 273, 475, 18552, 395, 9007, 246, 2902, 445, 339, 11, 24767, 253, 419, 431, 2689, 12742, 37623, 369, 22245, 432, 253, 1783, 273, 247, 2159, 330, 14, 14104, 3425, 5774, 44389, 14, 19, 16989, 14, 24, 14, 21151, 14, 21, 4253, 39, 21, 94, 187, 187, 35515, 11082, 187, 23380, 187, 187, 4118, 17826, 14, 15408, 7665, 28421, 285, 25617, 14, 6820, 355, 18054, 28421, 187, 187, 41331, 14, 15408, 7665, 28421, 313, 7510, 14, 2350, 41, 10, 285, 25617, 14, 6820, 355, 18054, 28421, 313, 12501, 34, 10, 403, 3164, 253, 1682, 14, 14091, 728, 4324, 432, 253, 8668, 273, 388, 9334, 275, 31046, 4787, 15, 19811, 70, 1994, 615, 14, 267, 26898, 28421, 2601, 313, 3837, 73, 38, 10, 556, 45764, 949, 253, 11781, 273, 767, 2601, 10625, 13, 9272, 34, 285, 5721, 14, 2350, 41, 285, 310, 2783, 281, 320, 247, 2234, 9548, 275, 2341, 11082, 275, 38167, 717, 262, 9217, 363, 366, 3861, 1346, 1254, 35, 3712, 1656, 20676, 2175, 327, 38167, 3861, 1346, 5183, 326, 2006, 73, 38, 14, 27676, 3608, 452, 644, 5705, 273, 2709, 3907, 354, 76, 552, 1584, 14, 936, 14, 70, 28420, 1584, 388, 9334, 84, 15, 1198, 1491, 670, 2006, 73, 38, 3470, 285, 38970, 90, 275, 38167, 3861, 1346, 359, 651, 1480, 10668, 281, 10414, 1254, 35, 3712, 2947, 35, 3583, 1656, 496, 1635, 281, 2045, 4342, 13, 359, 3636, 5721, 14, 2350, 41, 275, 1959, 14, 22763, 13223, 1171, 14293, 437, 684, 285, 39173, 706, 2352, 313, 2887, 14117, 1873, 544, 18, 1084, 52, 18, 910, 709, 14, 881, 568, 6962, 14, 4990, 2536, 2053, 6430, 3894, 689, 2456, 6, 8898, 3527, 6489, 342, 10741, 26663, 84, 15, 11279, 273, 23165, 6260, 1804, 326, 253, 767, 34835, 9288, 5721, 14, 2350, 41, 14, 27676, 3608, 10939, 432, 8244, 2905, 354, 76, 552, 4787, 15, 380, 5721, 14, 2350, 41, 5202, 2797, 275, 436, 1263, 310, 2011, 275, 14117, 1873, 544, 18, 1084, 52, 18, 910, 709, 14, 881, 568, 6962, 14, 4990, 7129, 9272, 34, 556, 644, 1119, 275, 1959, 3811, 13223, 1171, 14293, 437, 684, 13, 1213, 18986, 412, 3205, 13, 285, 39173, 706, 2352, 313, 2887, 14117, 1873, 544, 18, 1084, 52, 18, 910, 709, 14, 881, 568, 6962, 14, 4990, 2536, 9272, 34, 6430, 275, 841, 1264, 34835, 921, 689, 2456, 6, 8898, 3527, 6489, 281, 3969, 10741, 4324, 285, 2556, 281, 253, 906, 273, 23165, 6260, 13, 23923, 949, 3907, 734, 13517, 21916, 432, 5799, 354, 76, 552, 3875, 17728, 313, 2887, 14117, 1873, 544, 18, 1084, 52, 18, 910, 709, 14, 881, 568, 6962, 14, 4990, 2536, 1777, 1190, 15716, 6260, 7052, 1329, 253, 1114, 7868, 314, 273, 13223, 1171, 14293, 23769, 285, 10741, 6430, 313, 7282, 1686, 426, 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644, 3786, 2361, 760, 323, 1049, 280, 297, 12813, 507, 1254, 35, 3208, 1656, 4276, 280, 297, 12813, 507, 3480, 253, 13227, 830, 273, 10399, 41, 15, 733, 556, 644, 2011, 326, 353, 50, 48, 7037, 684, 323, 13227, 10399, 41, 275, 253, 308, 4280, 5880, 275, 436, 23009, 1254, 35, 3011, 1656, 187, 187, 1231, 1119, 767, 353, 50, 48, 14, 27676, 3608, 275, 253, 475, 44, 15, 1517, 4534, 11, 24422, 941, 15, 2053, 3894, 3925, 6, 8898, 3527, 3425, 6489, 285, 670, 7127, 6, 6489, 342, 616, 10741, 26663, 84, 15, 6295, 452, 18379, 16672, 6867, 323, 475, 44, 15, 1517, 4534, 11, 47745, 16202, 3608, 313, 3235, 544, 19, 1084, 53, 19, 910, 709, 14, 881, 568, 2420, 2536, 6915, 3425, 14259, 17891, 13, 359, 3636, 26663, 84, 273, 253, 475, 44, 15, 1517, 4534, 11, 41488, 48, 275, 2067, 3417, 273, 13223, 1171, 14293, 437, 684, 285, 419, 431, 2689, 12742, 313, 2887, 14117, 1873, 544, 18, 1084, 52, 18, 910, 709, 14, 881, 568, 6962, 14, 4990, 2536, 1777, 1190, 15716, 6260, 1329, 253, 1114, 7868, 314, 273, 253, 767, 3608, 3636, 275, 475, 44, 15, 1517, 4534, 5355, 7282, 1686, 426, 11422, 10543, 378, 4785, 426, 337, 15, 17, 10, 7738, 326, 597, 23923, 475, 13917, 11, 20857, 35793, 846, 253, 475, 44, 6950, 571, 11, 395, 475, 44, 7694, 351, 249, 1514, 11, 69, 2373, 9515, 15, 1777, 1190, 15716, 6260, 1659, 419, 431, 2689, 12742, 285, 13223, 1171, 14293, 437, 684, 1561, 581, 37623, 313, 7282, 1686, 426, 11130, 10543, 17641, 43498, 426, 8688, 10543, 2667, 15, 544, 22, 34, 1084, 39, 22, 910, 709, 14, 881, 568, 926, 2536, 380, 954, 13328, 15329, 784, 8813, 323, 253, 2540, 353, 50, 48, 14, 13432, 5202, 18080, 310, 247, 419, 431, 7868, 442, 14, 936, 14, 23341, 1171, 14293, 23769, 388, 9334, 326, 5866, 2393, 275, 13223, 1171, 14293, 23769, 5606, 15, 187, 187, 22367, 3980, 304, 968, 273, 767, 4691, 366, 16, 16573, 531, 7495, 410, 1586, 511, 313, 41488, 48, 10, 30246, 275, 26595, 267, 306, 311, 682, 12530, 1401, 34, 12530, 13993, 5202, 273, 353, 50, 48, 36566, 22886, 15, 378, 15, 13993, 5202, 273, 353, 50, 48, 36566, 329, 15, 380, 3904, 1840, 285, 2708, 253, 12998, 403, 253, 1543, 273, 13993, 285, 11356, 28551, 6260, 13, 2975, 15, 7214, 28551, 2193, 12667, 3925, 6, 403, 2011, 15, 380, 5026, 12998, 5224, 12667, 470, 15, 2222, 12637, 5912, 432, 247, 26812, 17032, 15, 25474, 16095, 403, 14495, 281, 253, 1180, 273, 35225, 591, 2670, 313, 2887, 4311, 8965, 481, 5642, 6492, 5937, 267, 306, 311, 684, 15, 7214, 10741, 6430, 326, 452, 247, 45523, 299, 14, 2877, 18315, 884, 8011, 938, 63, 936, 26663, 84, 275, 31046, 4787, 403, 2908, 275, 841, 7139, 15, 35876, 273, 253, 353, 50, 48, 14, 27676, 3608, 326, 452, 644, 5421, 21657, 905, 3439, 13, 7288, 13, 8988, 696, 403, 1677, 275, 26609, 5774, 44389, 14, 19, 16989, 14, 24, 14, 21151, 14, 22, 4253, 39, 22, 94, 187, 187, 14102, 28761, 13, 5301, 273, 253, 353, 50, 48, 6430, 3636, 275, 13223, 1171, 14293, 437, 684, 285, 419, 431, 2689, 12742, 313, 41488, 48, 14, 13432, 10, 342, 253, 1049, 280, 297, 12813, 266, 353, 50, 48, 313, 41488, 48, 14, 34, 10, 921, 326, 841, 4324, 3894, 1534, 14259, 760, 387, 253, 2159, 427, 14, 14104, 401, 2350, 14, 13018, 10625, 313, 1423, 6, 4583, 8898, 3527, 3425, 6489, 481, 380, 1783, 273, 253, 2601, 3268, 285, 38970, 90, 2692, 326, 353, 50, 48, 14, 13432, 285, 353, 50, 48, 14, 34, 452, 644, 9288, 407, 5937, 267, 306, 311, 684, 432, 1027, 10741, 17728, 949, 3907, 3700, 3394, 313, 30155, 15, 544, 22, 34, 13, 608, 35, 1084, 39, 22, 910, 709, 14, 881, 568, 926, 2536, 380, 958, 326, 353, 50, 48, 14, 34, 2722, 4585, 14259, 281, 26663, 84, 275, 299, 4277, 1233, 29951, 313, 455, 45523, 12830, 342, 299, 14, 2877, 18315, 884, 8011, 938, 13146, 5936, 326, 1049, 280, 297, 12813, 507, 9288, 353, 50, 48, 14, 34, 432, 436, 10741, 1387, 15, 15388, 862, 84, 273, 353, 50, 48, 14, 13432, 452, 644, 3636, 275, 2709, 10741, 34835, 1690, 5882, 280, 2279, 13, 20143, 29951, 13, 285, 1264, 1233, 13385, 451, 2390, 27, 9765, 15770, 9840, 15770, 285, 17356, 1233, 29951, 15, 4129, 253, 5202, 18080, 313, 1470, 15, 544, 22, 34, 1084, 39, 22, 910, 709, 14, 881, 568, 926, 7547, 1057, 417, 1581, 441, 281, 4271, 253, 10741, 14773, 273, 253, 353, 50, 48, 14, 13432, 275, 5937, 267, 306, 311, 684, 13, 253, 3361, 273, 427 ]	data. To the best of our knowledge, the functions of these proteins have not been studied in eukaryotes. According to TargetP and MitoProt, CAS-like proteins in K. brevis(P = 0.763 and P = 0.870 respectively), K. micrum(P = 0.742 and P = 0.951), and a green alga Ostreococcus tauri(P = 0.748 and P = 0.706) are mitochondrial targeted. CAS-like proteins in O. lucimarinusand Chlamydomonas reinhardtiido not have an N-terminal extension. PSORT \[[@B50]\] predicts a peroxisomal localization for the fungal CAS-like proteins however, with low probability (P-value range = 0.500 -- 0.660). Phylogenetic analyses of the CAS-like proteins (Fig. [4](#F4){ref-type="fig"}) support the monophyly of the two chromalveolate lineages (BPml = 87%; BPnj = 87%; BPP = 0.99) and places chromalveolates in one clade with a cyanobacterium Trichodesmium erythraeumIMS101 (BPml = 100%; BPnj = 100%; BPP = 1.0). Most proteins of cyanobacterial origin were derived by chromalveolates from red or green algal progenitors of their plastids via secondary endosymbiosis \[[@B25],[@B26]\]. Absence of Plantae from the cyanobacterial-chromalveolate clade likely indicates that this cyanobacterial protein was acquired by chromalveolates not through endosymbiotic but rather through horizontal gene transfer. Recently, Waller at al. \[[@B15]\] reported another case of cyanobacterium-to-dinoflagellate HGT that involved a DNA fragment encoding the plastid targeted shikimate-O-methyltransferase junction protein. However, presence of the CAS-like proteins in haptophytes suggests a different scenario for the occurrence of this enzyme in dinoflagellates, which might include an additional, haptophyte-to-dinoflagellate HGT. Alternatively the CAS-like protein tree topology could be explained by the gene transfer from cyanobacteria before the divergence of chromalveolates and its subsequent loss from stramenopiles, ciliates, and apicomplexans. ![Origin of clavaminic acid synthetase (CAS) -like protein in Chromalveolata. ML tree of CAS and CAS-like proteins. The numbers above and below the branches are the results of ML and NJ bootstrap analyses, respectively. Only bootstrap values ≥ 60% are shown. The thick branches indicate ≥ 0.95 posterior probability from Bayesian inference. Branch lengths are proportional to the number of substitutions per site (see the scale bar). CH indicates chromalveolates. The name of the CAS protein-encoding gene that has been studied experimentally \[49\] is given in brackets. \* The position of Alexandrium tamarensewithin the haptophytes clade was inferred from the analysis of a short C-terminal sequence.](1471-2148-7-173-4){#F4} Energy metabolism ----------------- ### Iron-containing alcohol dehydrogenase and NAD-dependent aldehyde dehydrogenase Iron-containing alcohol dehydrogenase (Fe-ADH) and NAD-dependent aldehyde dehydrogenase (PutA) are probably the best-studied proteins from the perspective of HGT in eukaryotes. Aldehyde-alcohol dehydrogenase protein (AdhE) has arisen through the fusion of two protein domains, PutA and Fe-ADH and is considered to be a key enzyme in energy metabolism in parasitic amitochondriate protists \[[@B51]\]. Previous studies on parasitic protists demonstrated that AdhE-encoding genes have been subjects of multiple independent prokaryote-to-eukaryote HGTs. For information about AdhE functions and phylogeny in parasitic protists we would direct readers to references \[[@B51],[@B52]\]. In addition to previous findings, we identified Fe-ADH in free-living dinoflagellates and jakobids (see Additional file [1](#S1){ref-type="supplementary-material"}). These sequences share over 50% amino acid identity with bacterial homologs. Results of phylogenetic analyses suggest that the two lineages acquired Fe-ADH-encoding genes independently from closely related prokaryotes. The Fe-ADH tree obtained in this study is shown in Additional file [1](#S1){ref-type="supplementary-material"}. PutA has been found in free living dinoflagellates, stramenopiles, and jakobids (see Additional file [1](#S1){ref-type="supplementary-material"}). PutA sequences in these three lineages show over 50% amino acid identity to corresponding bacterial proteins and according to the result of phylogenetic analyses, originated through independent interdomain transfers from distinct prokaryotic donors (see Additional file [1](#S1){ref-type="supplementary-material"}). Phylogenetic analyses strongly support the monophyly of dinoflagellate and bacterial sequences (BPml = 100%; BPnj = 100%; BPP = 1.0) and suggest that dinoflagellates acquired PutA before the divergence of Kareniaand Karlodinium. ### Malate-quinone oxidoreductase Malate-quinone oxidoreductase (MQO) is a functional analog of the better-known NAD-dependent malate dehydrogenase (MDH) that catalyses the conversion of malate to oxaloacetate in the tricarboxylic acid (TCA) cycle. In contrast to MDH, bacterial MQO is a membrane-associated enzyme that utilizes flavin adenine dinucleotide (FAD) as a cofactor and donates the electrons from malate oxidation to quinones instead of NAD \[[@B53]-[@B55]\]. MQO is protein common in bacteria. Among eukaryotes, this enzyme has been previously reported only for apicomplexans \[[@B56]\]. Apicomplexans lack the mitochondrial form of MDH. It has been shown that MQO compensates for mitochondrial MDH in the TCA cycle in this lineage \[[@B57]\]. We found two MQO-encoding genes in the K. brevisEST data. These share 60% amino acid sequence identity and about 44% identity with their bacterial homologs. Both have nucleotide compositions typical for K. brevisnuclear encoded genes (Table [2](#T2){ref-type="table"}). Using sequence similarity searches, we identified homologs of the K. brevisMQO in several species of dinoflagellates and haptophytes (see Additional file [1](#S1){ref-type="supplementary-material"}). Phylogenetic analyses support the monophyly of the two genes identified in K. brevis(BPml = 87%; BPP = 1.0) suggesting that they originated viagene duplication after the Kareniaand Karlodiniumdivergence. Phylogenetic analyses place haptophytes and dinoflagellates within one clade (BPml = 84%; BPnj = 99%; Fig. [5A](#F5){ref-type="fig"}). The most parsimonious explanation for the observed MQO-DH tree topology is a haptophyte-to-dinoflagellate HGT that occurred early in dinoflagellate evolution. ![Origins of two malate/quinone oxidoreductase (MQO) isoforms in Chromalveolata. A. ML tree of MQO isoform DH. B. ML tree of MQO isoform A. The numbers above and below the branches are the results of ML and NJ bootstrap analyses, respectively. Only bootstrap values ≥ 60% are shown. The thick branches indicate ≥ 0.95 posterior probability from a Bayesian inference. Branch lengths are proportional to the number of substitutions per site (see scale bars). CH indicates chromalveolates. Only bacterial sequences that have a BLAST e-value ≤ 10^-20^to homologs in eukaryotes are included in these trees. Names of the MQO-encoding genes that have been studied experimentally \[54, 55, 57\] are given in brackets.](1471-2148-7-173-5){#F5} Surprisingly, comparison of the MQO sequences identified in dinoflagellates and haptophytes (MQO-DH) with the apicomplexan MQO (MQO-A) show that these proteins share significant similarity only at the short N-terminal FAD-binding domains (22% overall amino acid sequence identity). The analysis of the protein distribution and phylogeny showed that MQO-DH and MQO-A have been acquired by chromalveolates from different bacterial donors through independent transfer events (Figs. [5A, 5B](#F5){ref-type="fig"}). The fact that MQO-A shows highest similarity to homologs in epsilon proteobacteria (all BLAST hits with e-value ≤ 10^-20^) suggests that apicomplexans acquired MQO-A from this bacterial group. Homologs of MQO-DH have been identified in multiple bacterial lineages including firmicutes, actinobacteria, and three proteobacterial groups: alpha-, beta-, and gamma proteobacteria. Although the tree topology (Fig. [5A](#F5){ref-type="fig"}) does not allow us to identify the bacterial donor of the MQO-DH in chromalveolates, the presence of N
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1503, 2517, 9882, 310, 19143, 1175, 13, 533, 417, 347, 1175, 347, 253, 41020, 457 ]	slim and surprisingly small and light it is, I consider it to be a rather unique hybrid that combines qualities of both the Touch and the Nano. It’s very colorful and lovely OLED screen is slightly smaller than the touch screen, but the player itself feels quite a bit smaller and lighter. It weighs about 2/3 as much, and is noticeably smaller in width and height, while being just a hair thicker. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. Zune and iPod: Most people compare the Zune to the Touch, but after seeing how slim and surprisingly small and light it is, I consider it to be a rather unique hybrid that combines qualities of both the Touch and the Nano. It’s very colorful and lovely OLED screen is slightly smaller than the touch screen, but the player itself feels quite a bit smaller and lighter. It weighs about 2/3 as much, and is noticeably smaller in width and height, while being just a hair thicker. Between me and my husband we’ve owned more MP3 players over the years than I can count, including Sansas, iRivers, iPods (classic & touch), the Ibiza Rhapsody, etc. But, the last few years I’ve settled down to one line of players. Why? Because I was happy to discover how well-designed and fun to use the underappreciated (and widely mocked) Zunes are. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. Apple now has Rhapsody as an app, which is a great start, but it is currently hampered by the inability to store locally on your iPod, and has a dismal 64kbps bit rate. If this changes, then it will somewhat negate this advantage for the Zune, but the 10 songs per month will still be a big plus in Zune Pass’ favor. I’ll gear this review to 2 types of people: current Zune owners who are considering an upgrade, and people trying to decide between a Zune and an iPod. (There are other players worth considering out there, like the Sony Walkman X, but I hope this gives you enough info to make an informed decision of the Zune vs players other than the iPod line as well.) If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. Between me and my husband we’ve owned more MP3 players over the years than I can count, including Sansas, iRivers, iPods (classic & touch), the Ibiza Rhapsody, etc. But, the last few years I’ve settled down to one line of players. Why? Because I was happy to discover how well-designed and fun to use the underappreciated (and widely mocked) Zunes are. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. The new Zune browser is surprisingly good, but not as good as the iPod’s. It works well, but isn’t as fast as Safari, and has a clunkier interface. If you occasionally plan on using the web browser that’s not an issue, but if you’re planning to browse the web alot from your PMP then the iPod’s larger screen and better browser may be important. The new Zune browser is surprisingly good, but not as good as the iPod’s. It works well, but isn’t as fast as Safari, and has a clunkier interface. If you occasionally plan on using the web browser that’s not an issue, but if you’re planning to browse the web alot from your PMP then the iPod’s larger screen and better browser may be important. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. The new Zune browser is surprisingly good, but not as good as the iPod’s. It works well, but isn’t as fast as Safari, and has a clunkier interface. If you occasionally plan on using the web browser that’s not an issue, but if you’re planning to browse the web alot from your PMP then the iPod’s larger screen and better browser may be important. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. Hands down, Apple’s app store wins by a mile. It’s a huge selection of all sorts of apps vs a rather sad selection of a handful for Zune. Microsoft has plans, especially in the realm of games, but I’m not sure I’d want to bet on the future if this aspect is important to you. The iPod is a much better choice in that case. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. The new Zune browser is surprisingly good, but not as good as the iPod’
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4446, 285, 326, 672, 13756, 281, 4796, 253, 9544, 13, 253, 8651, 4757, 10445, 310, 3777, 15, 187, 688, 1798, 13, 1580, 247, 1781, 9777, 273, 6024, 3490, 310, 33916, 327, 253, 2613, 5110, 8437, 3066, 253, 30033, 13278, 285, 253, 12206, 5110, 13062, 672, 253, 7592, 399, 310, 8038, 285, 5176, 13, 247, 17095, 4757, 310, 2424, 15, 5838, 326, 347, 342, 253, 30033, 5694, 275, 313, 40504, 15027, 1621, 15, 374, 582 ]	a base portion, 102 a cylindrical bearing holding portion provided substantially at a central portion on an upper surface of the base portion, 103 a bearing portion held in an inside of the bearing holding portion 102, 104 a thrust plate fittingly fixed in a lower opening of the bearing holding portion 102, 104a a thrust bearing sheet, 105 a stator, which will be described later on, made up of a stator core and coils and provided in such a manner as to surround circumferentially the bearing holding portion 102, 105a a stator core, 105b a coil wound around each of tees of the stator core 105a, 106 a circuit board affixed to the upper surface of the base portion 101, 107 a Hall element electrically connected and fixed to an upper surface of the circuit board 106, 108 a spindle rotatably supported on the bearing portion 103, 109 a turntable fixed to the spindle, 109a an annular yoke made to suspend vertically from an outer circumferential portion of the turntable 109, 110 an annular magnet provided on an inner side of the yoke portion 109a in such a manner as to oppositely face distal end portions of the tees of the stator core 105a, 111 a slip preventive material affixed near an outer circumferential portion of an upper surface of the turntable 109, 112 a disk holding portion provided at a central portion of the upper surface of the turntable 109 to hold a disk placed on the turntable 109, 113 a disk holding claw provided in such a manner as to move into and out of a sliding groove portion formed in such a manner as to extend from an outer circumferential portion of the disk holding portion 112 towards a central portion thereof, 114 a spring provided in an inside of the sliding groove portion so as to bias the disk holding claw 113 in such a manner as to protrude from the outer circumferential portion of the disk holding portion 112, 115 a hook locking portion formed an outer circumferential portion of an upper end portion of the bearing holding portion 102, and 116 a hook portion provided at a predetermined portion on a lower surface of the turntable 109 in such a manner as to be brought into engagement with the hook locking portion 115. In the conventional disk drive 100 that is configured as has been described above, a plurality of hook portions 116, which are formed by curving a metallic material, are provided around a circumference of the spindle 108, and the hook portions 116 are brought into engagement with the hook locking portion 115 on of the bearing holding portion 102 in such a state that the spindle 108 is securely inserted into the bearing portion 103, whereby the floating of the turntable 109 in association with the removal of an installed disk is prevented to thereby prevent the dislodgement of the spindle 108 from the bearing portion 103. In addition, the base portion 101 is formed by being punched from a relatively thick sheet metal so as to be imparted a predetermined mechanical strength because a load is exerted thereon when a disk is installed and removed. The stator core 105a is fixed to the bearing holding portion 102 at an inner circumferential portion thereof and is provided above the base portion 101 at a predetermined interval. In addition, an annular magnet 117 is adhesion fixed to an upper surface of the inner circumferential portion of the stator core 105a, so that the floating of the turntable 109 while rotating is prevented by virtue of a magnetic attraction force which attracts a lower surface of the turntable 109. In addition, the base portion 101 and the thrust plate 104 are strongly fixed to the bearing holding portion 102 by plastically deforming annular portions 102a, 102b which are provided on a lower surfaces of the bearing portion 102 through pressing. Additionally, a predetermined gap 118 is imparted between a lower portion of the disk holding claw 113 and the upper surface of the turntable 109. Next, a state will be described in which a disk is installed using FIGS. 16(a) to (d) which are sectional views of a main part of the conventional disk drive 100 showing a process of installation of a disk D. Here, FIG. 16(a) is a sectional view of a main part of the conventional disk drive which shows a state resulting before the installation of the disk D, FIG. 16(b) is a sectional view of the main part of the conventional disk drive which shows a state resulting at an initial stage of the installation of the disk D, FIG. 16(c) is a sectional view of the main part of the conventional disk drive which shows a state resulting at a middle stage of the installation of the disk D, and FIG. 16(d) is a sectional view of the main part of the conventional disk drive which shows a state resulting after the installation of the disk D, with the spring 114 omitted for the purpose of easing the understanding of the process. Firstly, as shown in FIG. 16(a), a gradient surface 113d which is inclined towards a radially outside of an upper surface portion 113c and a radially outside distal end portion 113b are formed on the disk holding claw 113. On the other hand, a sliding surface 112a which is inclined radially inwardly is provided on the disk holding portion 112 at a position which oppositely faces a distal end lower surface 113a of the disk holding claw 113. Next, as shown in FIG. 16(b), the disk holding claw 113 slides in a radially inward direction indicated by an arrow along the sliding surface 112a. Furthermore, as shown in FIG. 16(c), a sliding amount of the disk holding claw 113 becomes maximum in such a state that an inner circumferential wall of a center hole of the disk D coincides with the distal end portion 113b of the disk holding claw 113. Then, as shown in FIG. 16(d), while the disk D is brought into engagement at the center hole thereof when the disk is brought into abutment with an upper surface of the slip preventive material 111 and the disk holding claw 113 is biased by the spring 114 (not shown) so as to protrude, since the gap 118 is imparted, the disk holding claw 113 tilts about a fulcrum 112b, and therefore, there is produced a state in which the upper surface 113c of the disk holding claw 113 protrudes further upwards than an upper surface 112c of the disk holding portion 112. The gradient surface 113d which is inclined radially outwardly is provided on an upper surface on a radially outside of the disk holding claw 113 with a view to reducing a protruding amount which is a vertical distance between the upper surface 113c of the disk holding claw 113 and the upper surface 112 of the disk holding portion 112 as one of the purposes of the provision thereof. On the other hand, a spindle motor, in which a plurality of window portions are opened along a circumferential direction of a base plate at predetermined intervals, is disclosed in (P JP-A-5-38115) as a conventional spindle motor that is used as a drive portion of the conventional disk drive. According to Patent Document No. 2, an axial length can be reduced by allowing part of each winding portion of a stator to enter the window portion, thereby making it possible to realize the thinning of the disk drive as a whole. Note that the stator is fixed to the base plate in such a state that an annular main body portion and distal end portions of tees of a stator core are brought into abutment with circumferential edge portions of the window portions. However, the conventional techniques have had the following problems. (1) In the conventional general disk drives, since the turntable is made by drawing or cutting a sheet metal, there have been caused problems that the weight of the turntable so made is increased, and when the thickness of the turntable is attempted to be reduced with a view to reducing the weight and thickness thereof, the strength of the turntable is decreased, and that a complex and trouble some working is required for a center portion thereof where a spindle is to be fixed. (2) In addition, since it is a general practice to form the turntable into a flat shape by drawing or cutting a sheet metal, there has been caused a problem that an unnecessary space is produced between a lower surface of the turntable and the bearing portion and the bearing holding portion, and hence the overall thickness of the disk drive becomes thick, making it difficult to make the disk drive thinner. (3) Since the hook portions 116 is made up of a separate member from the turntable 109, there have been caused problems that the number of component is increased and that the number of manufacturing manhours required for a press bonding or welding process of fixing the hook portion 16 to the lower surface of the turntable 109 is increased, and additionally, since when attempting to thin the disk drive 100, a vertical length of the hook portion 116 is reduced, there has been caused a problem that a sufficient flexibility cannot be imparted to the hook portion 116, thereby making it difficult to mount the hook portion on the turntable 109. (4) Since the disk holding claw 113 is not only pushed to a center side of the disk holding portion 112 but also slides downwards when the disk D is installed, there has been caused a problem that the predetermined gap 118 becomes necessary on the upper surface side of the turntable 119 for allowing the disk holding claw 113 to slide downwards, this increasing the overall thickness of the disk drive. (5) In addition, since a punched sheet metal is used as the base portion 101, there have been caused problems that not only the thickness but also the weight of the disk drive is increased, thereby making it difficult to reduce the weight and thickness of the disk drive and that when attempting to reduce the thickness, the mechanical strength thereof is reduced. In particular, since a large magnitude of external force is exerted on the base portion 101 via the spindle 108 and the bearing portion 103 when the disk D is installed and removed, a predetermined strength is required. Note that as with the spindle motor in (Patent Document No. 2),
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811, 72, 44732, 6489, 13, 23512, 187, 187, 395, 7629, 13, 3495, 1253, 1348, 13, 3349, 1253, 1717, 187, 187, 41032, 589, 13, 11116, 13, 32455, 13, 28534, 1253, 1967, 187, 187, 42665, 4204, 26002, 13, 19580, 15916, 13, 7288, 13, 8978, 13, 9934 ]	–98 Cambridge Declaration on Consciousness, 239 Carhart-Harris, Robin, 214–15, 217, 230 Case, Laura, 194 _C. elegans,_ 65–66, 66n, 238–39, 254–55 Center for Gender Sanity, 192 Central Intelligence Agency (CIA), 221–22 central nervous system, 62, 120. _See also_ neurons (nerve cells) _The_ _Cerebral Cortex of Man_ (Penfield), 57 Chalfie, Martin, 66 Chandler, Arthur, 220–21 Chandler, Raymond, 107 Châtelet, Émilie du, 168 Cheap Date gene, 108–9, 109n, 112, 134 Chemero, Anthony, 159–61 Child, Julia, 33 Childhood Gender Nonconformity (CGN), 195 chimerism, 36–37 Chivers, Meredith, 172, 179, 180, 181–82, 196, 197 chromosomes, 25, 26–27 Churchland, Patricia, 237–39, 242, 245, 248, 249, 255–56 Churchland, Paul, 237 claustrum, 241 Clendinen, Dudley, 260 cluster headaches, 225–26 cognitive dissonance, 194, 278 Colbert, Stephen, 174 Coleman, Sidney, 232 Coleman, Todd, 163–64 comas, 54, 242–43, 244 _Confessions of an English Opium Eater_ (De Quincey), 122–23 connectome, 63–68, 165, 280 "conscientiousness" personality factor, 90, 142, 142n, 146, 154, 244–45, 258 consciousness, 141, 235–39, 240–46, 246–50, 250–56, 256–59 Controlled Substances Act, 223 Cool, Nadean, 276 Cooper, Anthony Ashley, 246 core self, 269–70 corpus callosum, 176–77, 277 Cowan, Jack, 217, 219 Crick, Francis, 16, 24, 26, 214, 214n, 241, 255 Csikszentmihalyi, Mihaly, 144–45 cues, 141, 155 _The_ _Cult of Personality Testing_ (Paul), 86 culture, 83, 182, 188–89, 197, 222 cytosine, 25, 27 Daisey, Mike, 278–80 Dalí, Salvador, 215 Damasio, Antonio, 244, 245 death, 231–32, 235–36, 256, 258–59 default mode network, 58–59, 215 delayed gratification, 125–26, 127 delerium tremens (DTs), 109, 111 Delysid, 220 dementia, 256–57 Denk, Winfried, 65 depression, 91, 97–104, 123, 124, 220, 231 De Quincey, Thomas, 122–23, 129 Descartes, René, 240–41, 245 _Diagnostic and Statistical Manual of Mental Disorders_ (DSM), 189, 190n Dick, Danielle, 119–20, 129, 132–33 "dissembling," 69 DMT (dimethyltryptamine), 206, 225 DNA (deoxyribonucleic acid), 13–16, 16–17, 24, 25, 27–28, 99, 214. _See also_ genes and genetics Doblin, Rick, 224–25 _Doors of Perception_ (Huxley), 214 dopamine, 63, 101–2, 104, 121, 134n, 225 Drake, Betsy, 220 Duffin, Shari, 43 Eagleman, David, 46, 242 earwax, 6, 28 Ecstasy, 206, 230 Educational Testing Service, 81 ego, 207, 209, 212–13, 215, 221 Ehrsson, Henrik, 161–62 _The_ _Electric Kool-Aid Acid Test_ (Wolfe), 207 emergent phenomena, 244–45, 245n, 258 Emma (transgendered person), 185, 192 Engel, Andreas, 250 Entheogen Corporation, 226 environmental influences and alcoholism, 124, 132 and brain physiology, 54, 64–65 and gender identity, 188–89 and individualism, 76, 83, 92, 96 interaction with genetics, 6–8, 28, 30, 42 _See also_ culture epidermal growth factor (EFG), 112 epilepsy, 56, 74n, 247, 277 "episodic future thought," 274–75 ergot and ergotism, 206, 210–11 Ermentrout, Bard, 217 _Essay Concerning Human Understanding_ (Locke), 246 estrogen, 199 ethanol, 107–11, 111–16. _See also_ alcohol and alcoholism evolution, 30–31, 69 existential fear, 231–32 extrastriate body, 58 extroversion, 78–79, 84, 90, 102, 146, 154–56 eyes, 34–37, 216–17 eyewitness testimony, 280 Facebook, 145–48 facial recognition, 56–59 failed relationships, 77–80 Fairchild, Lydia, 36–37 false memories, 275–78 family histories, 111, 124 Fausto-Sterling, Anne, 186–87, 191 Featherstone, David, 175 Federal Bureau of Investigation (FBI), 223 "feeling" (personality dimension), 79, 81, 83–84 feeling regulators, 141–42, 142–43 Ferguson, Craig, 129–30, 134, 229–30 fetal development, 177, 178, 185 Feynman, Richard, 214 fight-or-flight response, 272 Fisher, Helen, 76 flashbacks, 222, 224 "flashbulb memories," 273 fMRI (functional magnetic resonance imaging), 47–48, 50, 55, 58, 68–71, 101–2, 131, 140, 214, 263 Foerster, Otfrid, 56 Forer effect, 85–86 Forster, E. M., 280 Fowler, Lorenzo, 52 Fowler, Orson, 52 Fox, Arthur L., 31 Franklin, Rosalind, 24 fraternal twins. _See_ twins Freud, Sigmund, 78–80 frontal lobes, 98, 128, 132n fruit flies ( _Drosophila melanogaster_ ), 107–11, 111–16, 175 Future Oriented persons, 126–27 Gage, Phineas, 53–54, 56, 66–67 Galen, 74n Gall, Francis, 51–55, 53 Gallant, Jack, 70–71 Galton, Francis, 4–5, 88, 170 gamma-aminobutyric acid (GABA), 63, 120, 133 Gates, Bill, 214 Gazzaniga, Michael, 277–78 gender and alcoholism research, 120–21 gender atypical behaviors, 167–72 gender expression, 195–201 gender identity, 189–94 online avatars, 153 personality traits, 83 self-representation, 155–56 sexual behavior in the natural world, 172–78 sexual orientation, 179–83 transgendered identity, 183–88 Gender and Family Project, 169 generative people, 268–69 genes and genetics and alcohol tolerance, 107–11, 111–16, 116n, 132–33, 134n and anxiety, 98–99 and Big 5 personality traits, 96–97 and depression, 99 and determinism, 6 and DNA, 25–27 and eye color, 34–37 and gender identity, 188 genome mapping and sequencing, 14, 16–17, 18, 20n, 64, 67, 110, 214 genotypes, 17, 39 and impulsivity, 128 incompletely dominant genes, 20n and Miescher's work, 24–25 and personality, 97–104 privatization of, 42n and risk factors, 39–40 and sexual orientation, 175–76 and transgendered identity, 185 and variation, 23–24, 28–29 Gerber, Andrew, 262, 269–70 Gil da Costa, Ricardo, 55, 59, 68
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Your aim, our aim, was to capture him, and you failed! My scouts are searching for him, Your Highness. And a reward has been offered. It will be your head if he's not found. - Lord Buchan. - Your Highness. You bring news of the Bruce? No, Your Highness, his wife and child. Marjorie, we've been riding horses for days. Are you not tired yet? No. English soldiers approaching, we have to go now. Get to the trees, I'll send horses and men. Go. Lord Fraser! We know you have the Bruces wife and child. Hand them over and I spare the castle! Draw! They are not here, Your Royal Highness. Loose! Theres no need to burn us down. I will open the gate. Neil, where's Robert? Your Highness, I dont know. Where are his wife and daughter? They left for Turnberry on Tuesday. They left for Turnberry on Tuesday? Ow! Elizabeth! Where is your brother? I swear I don't know. I swear I don't know! - Uncle Neil! - I swear! - You forced my hand, Neil. - Elizabeth! - I swear! - Let him go! - I swear I don't know! - What are they doing? - No, please. I swear. - Uncle Neil! No! No! Look at me! No, no! No! No! Stop! No, Neil! Where is your husband? We dont know. We dont know. Please, have mercy. Your father is a tyrant, you are not. You think me weak? Compassion is not weakness. I have all the traits my father has, save one: mercy. Fraser. You seem like a... reasonable man. Where's the Bruce? I truly dont know. Hang them both up for all to see what becomesof those who support the outlaw Bruce. Take the women to England, seize all his lands. Leave him with nothing. See you later. Come on. Lord Mackinnon. I heard a rumor you made yourself king, and the Prince is tearing Scotland apart looking for you. I've come to ask for your support. My men and I stood with Wallace at Falkirk. Where were you then? There was no winning Falkirk. You know that. How can I follow a man who's never won an open battle? From what I've been told, you barely escaped Methven alive. We were ambushed in the dead of night. How many men have you? Forty. I'm still rounding people up. I wish you luck. I truly do. Come on, Lachlan! I've known you for over 25 years. - Now just please, give us some people... - Angus! - We've come here for your help. - Are you done? I believe, in time, you'll change your mind. And I'll be waiting. Move. Good to see you all again! Hamish, how you doing? How you doing, boy? My darling! Where the fuck have you been? You said three weeks, its been four months! Much has happened, my love. Oh, Angus. - Maybe I'll see you later, then. - Sure. Is that Robert? Our new king. Aye. Welcome, Your Majesty. It's good to see you again, Aine. Come! Lets get you warm and fed. One man to down the horse. And one man to remove the knight. And then to kill him. Weak spots under the arm, the neck... On your feet. And in the groin. You go near my daughter again, I'll cut them off and use them as bait. Are we clear? What you doing, you bastard? - I'll kick your bloody arse, Douglas, eh? - You taste sweeter! You think that's bloody funny? Right. Who's next? Thank goodness. I'm to take the girl to our convent for religious training. Only the girl. Oh. Isn't that wonderful? The sisters want to look after you. And they are gonna take such good care of you. Come, child. Are you coming? No. No, but... we'll all be home again soon. I'm certain of it. And Father? Mm-hmm. Come on. Come here. - No. - Come on, Marjorie. Please, don't make this hard. No, I don't want to go! No! Marjorie, I'll see you soon. I promise. I love you. - No, I want to go back! - I love you. - You'll be fine. - Let go! No. Elizabeth! Let go of me! Elizabeth! Your Grace. Angus's other daughter. Oh, here he comes. This could get interesting. Kildrummys fallen. Every man massacred. Your brother was hanged, drawn and quartered. My wife? My daughter? Theyre both alive. Taken by the Prince. We have to go back. You wanted to be king. Well, you're king now. This is the price you pay. We only win if you survive. Thinking about revenge? I know the feeling. It tears at the soul. But it can also be a weapon. No more chivalry. Now we fight like wolves. Open the gate. - You know him? - Aye. Come on, James. Whoa! Whoa, whoa, whoa! Lord Bruce. Your Majesty. Your Majesty. Iain. Youre late. Where have you been? Aye, sorry. Wheel came clean off. Took an age to fix it. Yeah, well, come on! Lets unload this before they gut the both of us. By the gate! What've you got in there? - Porridge. - Oh... I'll have some of that, then. Come on, get me a bowl. Of course. Come on! Follow me! Die, you bastard! To the stairs! Follow me! Arm yourselves!Arm yourselves! Seamus. Are you all right? Your Majesty! Its good to have you home. We cant stay. Theyll know where we are. - Youre all to come with us. - Aye. We take what we can, and burn it down. - Gayle! - Leave nothing for the enemy. Burn it! Burn it all! This is how we do it. We travel in stealth. Strike without warning. Take the land back castle by castle, destroying them as we go. Its not exactly chivalry, but I like it. Burn it all and take what you can! Let's move! Robert, you know, my fathers land is only a days ride. It would mean so much to me if I could take it myself. You know, Id only need two or three men. Take five. And keep your wits about you. I've already lost two brothers, I can't bear to lose another. Everyone out! Good luck, boy. Palm Sunday... Alleluia! Alleluia! Douglas! Douglas! I watched once, from that very window, my mother and father standing in this courtyard. And my father whispering in my mothers ear. I dont know what he said, but it must have been funny because she... she couldnt stop laughing. I used to drink this water. Poison it. Throw the bastards down the well. Wheres that cunt Clifford? Hes gone to join Valence, my lord. Well, then, Ill see him soon enough. Friends, don't be afraid. Please join me. No! Come, enjoy this Palm Sunday feast. It was prepared for your enemies. It is yours now. As is everything in my familys castle. I serve Robert Bruce, King of Scots! Join us to free our land! Sir Richard's castle in Scotland has also fallen. The man responsible may have been mad. He was heard screaming the same word over and over. Douglas. He claimed to be fighting for Robert the Bruce. The outlaws continue to sack their own castles, and as word of Bruce's exploits spreads, so does his support amongst the people. Of course, there are still nobles who remain loyal to the Crown. This morning... I woke up... performed my ablutions, and then walked from my bedchamber to the great hall. And on the way, I stumbled. No reason, just... just lost my footing. Well, I lose my footing sometimes. Especially in the morning when the body is still waking up. It was my hope to grow old and not die on the battlefield. But I see now that the great danger in a deathfrom natural causes is that one may be lying in one's bedchamber, thinking of all the things that have been left undone. Fear not, Father. We will not fail you again. Well, you managed to imprison a few women. These gentlemen of France were in the dungeon. They wish to join us. Is it true? Youre the King of Scots? He certainly is, you cheeky wee shite. Hey. Go tell all your friends were going to win our country back. Aye, Sire. Come on, Arthur. Is that really the King? Robert.I bring more men. - Drew! - Your Majesty. - Good to have you back! - We found them on the road. We thought you were dead! They tried to ambush us! I have something for you, Sire. I managed to take it from Methven. Rise. You look after this for me. Youve done a grand job so far. I'll guard it with my life. It's good to have you back. It's all right. All's well, Elizabeth. You're here! It's all right. We missed you.
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17, 15, 17, 15, 19, 14, 18, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 3649, 15766, 11955, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 14983, 462, 14, 43824, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 6682, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 35399, 14, 43824, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 35399, 14, 44902, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 69, 31785, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776, 84, 14, 4233, 10425, 1714, 64, 19, 15, 17, 15, 19, 14, 19, 393, 187, 50263, 545, 13776, 84, 14, 69, 31785, 16, 545, 13776 ]	clcpp-minimal-timer_0.9.2-2 \ examples/examples-rclcpp-multithreaded-executor_0.9.2-2 \ examples/examples-rclpy-executors_0.9.2-2 \ examples/examples-rclpy-minimal-action-client_0.9.2-2 \ examples/examples-rclpy-minimal-action-server_0.9.2-2 \ examples/examples-rclpy-minimal-client_0.9.2-2 \ examples/examples-rclpy-minimal-publisher_0.9.2-2 \ examples/examples-rclpy-minimal-service_0.9.2-2 \ examples/examples-rclpy-minimal-subscriber_0.9.2-2 \ geometry2/examples-tf2-py_0.13.4-2 \ fastcdr/fastcdr_1.0.13-2 \ fastrtps/fastrtps_2.0.0-4 \ rosidl-typesupport-fastrtps/fastrtps-cmake-module_1.0.1-2 \ filters/filters_2.0.0-2 \ fmilibrary-vendor/fmilibrary-vendor_0.2.0-2 \ foonathan-memory-vendor/foonathan-memory-vendor_1.0.0-2 \ geographic-info/geodesy_1.0.4-2 \ geographic-info/geographic-info_1.0.4-2 \ geographic-info/geographic-msgs_1.0.4-2 \ common-interfaces/geometry-msgs_2.1.0-1 \ geometry2/geometry2_0.13.4-2 \ googletest/gmock-vendor_1.8.9000-2 \ google-benchmark-vendor/google-benchmark-vendor_0.0.2-1 \ gps-umd/gps-msgs_1.0.3-2 \ gps-umd/gps-tools_1.0.3-2 \ gps-umd/gps-umd_1.0.3-2 \ gps-umd/gpsd-client_1.0.3-2 \ googletest/gtest-vendor_1.8.9000-2 \ rosidl-typesupport-gurumdds/gurumdds-cmake-module_1.0.2-1 \ ifm3d-core/ifm3d-core_0.18.0-5 \ image-common/image-common_2.3.0-2 \ vision-opencv/image-geometry_2.2.1-1 \ image-pipeline/image-pipeline_2.1.1-2 \ image-pipeline/image-proc_2.1.1-2 \ image-pipeline/image-publisher_2.1.1-2 \ image-pipeline/image-rotate_2.1.1-2 \ demos/image-tools_0.10.0-1 \ image-common/image-transport_2.3.0-2 \ image-transport-plugins/image-transport-plugins_2.3.0-2 \ image-pipeline/image-view_2.1.1-2 \ interactive-markers/interactive-markers_2.1.2-1 \ demos/intra-process-demo_0.10.0-1 \ joint-state-publisher/joint-state-publisher_2.2.0-2 \ joint-state-publisher/joint-state-publisher-gui_2.2.0-2 \ joystick-drivers/joy_2.4.1-2 \ joystick-drivers/joy-linux_2.4.1-2 \ kdl-parser/kdl-parser_2.4.0-2 \ laser-geometry/laser-geometry_2.2.0-4 \ laser-proc/laser-proc_1.0.1-2 \ launch/launch_0.10.2-2 \ launch-ros/launch-ros_0.10.2-2 \ launch/launch-testing_0.10.2-2 \ launch/launch-testing-ament-cmake_0.10.2-2 \ launch-ros/launch-testing-ros_0.10.2-2 \ launch/launch-xml_0.10.2-2 \ launch/launch-yaml_0.10.2-2 \ lgsvl-msgs/lgsvl-msgs_0.0.3-2 \ resource-retriever/libcurl-vendor_2.3.2-2 \ libg2o/libg2o_2020.5.29-2 \ phidgets-drivers/libphidget22_2.0.2-2 \ libstatistics-collector/libstatistics-collector_1.0.1-2 \ libyaml-vendor/libyaml-vendor_1.0.2-2 \ demos/lifecycle_0.10.0-1 \ rcl-interfaces/lifecycle-msgs_1.0.1-1 \ demos/logging-demo_0.10.0-1 \ navigation-msgs/map-msgs_2.0.2-3 \ marti-messages/marti-can-msgs_1.1.0-2 \ marti-messages/marti-common-msgs_1.1.0-2 \ marti-messages/marti-dbw-msgs_1.1.0-2 \ marti-messages/marti-nav-msgs_1.1.0-2 \ marti-messages/marti-perception-msgs_1.1.0-2 \ marti-messages/marti-sensor-msgs_1.1.0-2 \ marti-messages/marti-status-msgs_1.1.0-2 \ marti-messages/marti-visualization-msgs_1.1.0-2 \ message-filters/message-filters_3.2.4-2 \ navigation-msgs/move-base-msgs_2.0.2-3 \ common-interfaces/nav-msgs_2.1.0-1 \ nodl/nodl-python_0.1.0-2 \ orocos-kinematics-dynamics/orocos-kdl_3.3.1-2 \ osrf-pycommon/osrf-pycommon_0.1.10-2 \ osrf-testing-tools-cpp/osrf-testing-tools-cpp_1.3.2-2 \ ros2-ouster-drivers/ouster-msgs_0.2.0-2 \ perception-pcl/pcl-conversions_2.2.0-2 \ pcl-msgs/pcl-msgs_1.0.0-3 \ demos/pendulum-control_0.10.0-1 \ demos/pendulum-msgs_0.10.0-1 \ perception-pcl/perception-pcl_2.2.0-2 \ performance-test-fixture/performance-test-fixture_0.0.2-1 \ phidgets-drivers/phidgets-accelerometer_2.0.2-2 \ phidgets-drivers/phidgets-analog-inputs_2.0.2-2 \ phidgets-drivers/phidgets-api_2.0.2-2 \ phidgets-drivers/phidgets-digital-inputs_2.0.2-2 \ phidgets-drivers/phidgets-digital-outputs_2.0.2-2 \ phidgets-drivers/phidgets-drivers_2.0.2-2 \ phidgets-drivers/phidgets-gyroscope_2.0.2-2 \ phidgets-drivers/phidget
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273, 253, 747, 3085, 380, 31466, 28193, 32393, 416, 2646, 285, 5490, 39035, 15, 380, 17325, 12127, 327, 247, 2098, 281, 18111, 4024, 3729, 13247, 48177, 10766, 38065, 14, 2447, 15, 187, 187, 1628, 510, 31466, 668, 556, 644, 4439, 5747, 14207, 15, 313, 38482, 27, 13817 ]	the response latency. In our experiments, the Netduino Plus (server) and the notebook (client) were placed close to each other (less than 1 m). ![Response latency vs. the number of sensor readings (removed TinySOS).](sensors-15-24343-g015){#sensors-15-24343-f015} 7. Conclusions and Future Work {#sec7-sensors-15-24343} ============================== 7.1. Conclusions {#sec7dot1-sensors-15-24343} ---------------- We conclude this paper in the final section by summarizing the research that has been carried out and outlining the conclusions drawn from the result. We also comment on the limitations and propose areas for future work. We began by choosing a class-1 IoT object as categorized in the framework of Bormann et al. \[[@B2-sensors-15-24343]\] for our development platform. Firstly, we equipped the class-1 IoT device with a Bluetooth transceiver in order to establish wireless network within a limited range. We standardized its connection by means of OGC PUCK. Due to the fact that Internet access is a key requirement for IoT devices, we applied additional software components to enhance this functionality for the Bluetooth-enabled PUCK instrument. In the second stage, we removed the intermediary gateway in the path between user and IoT device by developing a web service on a Thing itself. Since device owners or manufacturers might have their own design for data representation, we introduced a lightweight version of the OGC SOS, TinySOS. As a result, the sensor measurements could be accessed remotely in a standardized way simply through a web browser. In accordance to the complicated nature of the OGC SOS, we proposed another approach which was more suitable for the class-1 IoT devices. As such, the third contribution of this research was integrating CoAP into the OGC SOS for which the SOS operations were processed on the CoAP proxy with enough computational resources. Due to the UDP transmission, CoAP could not establish a direct connection to the Internet components without the deployment of CoAP proxies. As the IoT will eventually follow the Internet protocol suite model, it is recommended to adjust network connections to be compatible with the Internet standard protocols. As a result, we designed a new application programming interface called OGC SensorThings API. The use cases of this API started with device registrations to the service. For the sensing devices, registration information contained the phenomenon that was observed. After registration, sensing devices could start uploading their observations to the data service. From the point of view of tasking, actuators could also register and publish their tasking capabilities to the data service. As a result, users were able to access those observations and also send controlling tasks to the devices through the service. All the communications with the data service followed the REST-like architecture. Finally, the four implementations on a class-1 IoT object (Netduino Plus) were assessed comparatively. Each implementation was evaluated according to memory occupation (RAM and ROM), request size, response length and response latency. As a case study, we embedded multiple meteorological sensors, sound pressure sensor and LED actuator to our Netduino Plus in order to demonstrate how different components work together. In summary, each of the protocols discussed in this research has its own negative and positive attributes which can effectively influence the protocol selection for application developers. According to the evaluation results, TinySOS and PUCK appeared significantly efficient in terms of ROM usage whilst the SOS over CoAP and the SensorThings API performed slightly better for RAM usage. Thus, PUCK and TinySOS are better candidates for memory-constrained applications. In terms of bandwidth efficiency, the experiments nominated CoAP and SensorThings which had small request and response sizes. Lastly, for real-time applications, TinySOS is not recommended at all since handling large XML documents is time-consuming for resource-constraint devices. 7.2. Future Work {#sec7dot2-sensors-15-24343} ---------------- This paper takes a practical approach to the interoperability in the Internet of Things. There are several ways in which this research can be improved and extended. In this section, some of the major issues that can later be investigated and guidelines of the future work are addressed. First of all, the aforementioned interoperable protocols follow the client-server architectural style which has the single point of failure (SPOF) issue \[[@B45-sensors-15-24343]\]. In order to address this issue, one potential solution is to design a peer-to-peer (P2P) architecture as it has been proven reliable and effective. In this case, devices can form an overlay network to discover resources and forward requests; so a centralized component such as the sensor registry service, CoAP proxy and SensorThings data service would be no longer needed. For this research, Bluetooth and Ethernet were considered as the network enablement technologies for IoT devices. Since Wi-Fi is dominant in network communications \[[@B46-sensors-15-24343]\], the study on Wi-Fi communications in the IoT is strongly recommended. One immediate issue in Wi-Fi connection is the transmission of network configuration to the IoT device which has no display equipment and input peripheral. In addition to Wi-Fi as wireless enablement for the IoT, research should be started on improving energy saving on the IoT devices. The first assumption for this research was IoT devices having unlimited power resources; however this assumption may not be true in many cases. Some sensor nodes will be battery-operated \[[@B26-sensors-15-24343]\], so energy is perhaps the most notable constraint for the IoT devices. Furthermore, achievement in Wi-Fi connection of IoT objects leads to removing wires and cords from devices. Therefore, their battery charge must be efficiently conserved to extend the life of the individual sensor nodes, and consequently the entire IoT network. One of the missing metrics in [Section 6](#sec6-sensors-15-24343){ref-type="sec"} was the evaluation of CPU usage in different protocols. The CPU usage refers to how much work a device's processor is doing. The main reason that we did not focus on this criteria in our evaluations was because there was no complex computation performed on the device. For example, in none of the four protocols, the device did not implement any JSON parser or XML parser which is heavy-weight for class-1 IoT devices. However, it is worth to compare the CPU usage for the existing workload of those protocols in the future. More potential future work pertains to privacy and security for IoT devices. We efficiently implemented existing security and privacy mechanisms of the information technology and computer networks on class-1 IoT devices \[[@B47-sensors-15-24343]\]. Although an acceptable level of secure connection in IoT can be achieved, we believe IoT would require specific rules and mechanisms for the successful implementation of this approach. Mohammad Jazayeri and Steve Liang conceived the original idea and investigated the possible solutions. Then, Mohammad designed the architectures and implemented the solutions. In order to evaluate the implementations, Alec Huang and Mohammad designed and performed the experiments. Finally, Mohammad wrote the manuscript which was revised by Alec. The authors declare no conflict of interest. A.1. Sample Requests and Responses Used in [Section 6.2](#sec6dot2-sensors-15-24343){ref-type="sec"} ==================================================================================================== In this section, requests and responses of the get observation operation for each of the four implemented protocols are presented. A.1.1. Simple Web Server ------------------------ ![HTTP GET request and response to the simple web server through the Internet.](sensors-15-24343-g016){#sensors-15-24343-f016} A.1.2. PUCK over Bluetooth -------------------------- ![GETREADING request and response to the PUCK-enabled Netduino Plus through Bluetooth.](sensors-15-24343-g017){#sensors-15-24343-f017} A.1.3. TinySOS -------------- ![GetObservation request to TinySOS using the 52 North test client tool.](sensors-15-24343-g018){#sensors-15-24343-f018} A.1.4. SOS over CoAP -------------------- ![GetObservation request to the SOSCoAP proxy using 52 North test client tool.](sensors-15-24343-g019){#sensors-15-24343-f019} ![GetObservation request to a CoAP server (i.e., Netduino Plus) using the SOSCoAP Proxy.](sensors-15-24343-g020){#sensors-15-24343-f020} A.1.5. OGC SensorThings API --------------------------- ![HTTP GET request and response to the OGC SensorThings through the Internet.](sensors-15-24343-g021){#sensors-15-24343-f021} ![Summarized response of the SensorThings.](sensors-15-24343-g022){#sensors-15-24343-f022} ![Response of the SensorThings to multiple readings request.](sensors-15-24343-g023){#sensors-15-24343-f023} Posts Unless you’ve been under a rock or living in a cave, you’ve heard of the flap over Sony Pictures release of the new film The Interview starring Seth Rogen and James Franco. The comedy centers on a plan to assassinate North Korean dictator Kim Jong-Un. “The Interview” has been released despite threats. (Credit: tech
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310, 671, 253, 6387, 273, 16706, 3290, 285, 3103, 275, 2176, 2219, 12834, 275, 253, 26880, 15, 187, 1147, 651, 2299, 320, 11408, 281, 8600, 253, 26880, 2403, 5199, 1679, 18213, 17193, 13, 275, 247, 2105, 3576, 5133, 13, 16682, 17749, 15840, 13, 17647, 285, 13367, 273, 253, 26880, 2403, 5199, 15, 187, 20210, 322, 15, 36, 15, 24792, 313, 36122, 10, 187, 12347, 322, 15, 38, 15, 19, 69 ]	and people with chronic conditions, such as heart disease, diabetes, and lung disease, are at higher risk of getting very sick from this illness. Although it is possible for everyone, including young people, to be affected, your individual risk is low.LATEST FROM THE CDC Watch for Symptoms People with COVID-19 have had a wide range of symptoms reported – ranging from mild symptoms to severe illness. Symptoms may appear 2-14 days after exposure to the virus. People with these symptoms or combinations of symptoms may have COVID-19: Fever Cough Shortness of breath or difficulty breathing Or at least two of these symptoms: Fever Chills Repeated shaking with chills Muscle pain Headache Sore throat New loss of taste or smell Purple or red bumps on toes, hands or feet If you are experiencing these symptoms, or have any other unusual symptoms, contact our office. *Emergency warning signs include difficulty breathing, persistent pain or pressure in the chest, new confusion, or bluish lips or face. If you develop emergency warning signs for COVID-19 get medical attention immediately. Take Precautions The best way to prevent illness is to avoid being exposed to this virus. We strongly recommend the following: If you have any flu-like symptoms, such as fever, a dry cough and/or shortness of breath, contact us.Blake Byrnes Blake Byrnes is a founding partner and CTO of BlueFletch, a 25-person boutique consulting firm focused on mobile solutions. Blake has a background architecting big web systems and hands-on experience with the major mobile platforms. He has built large scale mobile solutions for big companies and brought product concepts to life for startups. Blake has started three companies in the past seven years. Prior to BlueFletch, he was founder and CEO of CrowdMind, co-founder of Less Meeting and managed teams as a consultant with Accenture. He graduated from the Duke University with a degree in Computer Science.The statements in this section merely provide background information related to the present disclosure and may not constitute prior art. Automotive vehicles typically utilize an internal combustion engine to provide the power to operate the vehicle. Internal combustion engines generate heat due to the combustion process and it is necessary to continuously remove the excess heat from the vehicle's engine in order to maintain the operating temperature of the vehicle's engine at a specified level. The usual method of removing this excess heat is an automotive cooling system. The cooling system utilizes a coolant pump which pumps coolant through the vehicle's engine to absorb the excess heat and then this heated fluid is pumped to a heat exchanger or radiator which removes the excess heat by performing a heat exchange process with ambient air. The coolant which has been cooled by the radiator is returned to the engine and the process continuously repeats itself. Typically, the temperature of the coolant is maintained at a minimum level using a thermostat or some other type of control system. In order to reduce the size and thus the costs of the radiator, the automotive designer strives to have the radiator operate in the most efficient manner. One method used to maximize the efficiency of the radiator is to control the flow of ambient air through the radiator. This is accomplished by providing a fan which draws the ambient air through the radiator and then providing a fan shroud which ensures that the maximum amount of air is drawn through the radiator. The maximization of ambient air flow requires that the fan be located within the fan shroud. A common problem with fans is the noise they generate during operation. The noise components generating the sound radiated by the cooling fan are tonal and overall noise. Tonal noise is a result of the rotation of the fan blades. Both tonal and overall noise are equally important for most cooling fans. Obstacles upstream and downstream of the fan create airflow disturbance and induce pressure fluctuation. Fan noise is typically caused by wall pressure fluctuation in the fan and shroud. This noise issue can be addressed by configuring the fan shroud to release this pressure thereby reducing the noise radiating from the cooling fan. The shroud must keep the same or equivalent airflow performance of the old design.'Same state, different world' The story on the southward migration of the “cultural Mason-Dixon line” brought to mind a visit to Richmond that my wife and I, then recent transplants from the Northeast, made years back. During a tour of the state Capitol, the guide asked people in the group where they were from. Several out-of-state locations were mentioned before she came to us. “Fairfax,” we replied. “Ah, yes,” she said. “Same state, different world.”The pinstriped teammate treaty between Kevin Youkilis, the Yankees’ new third baseman and former Red Sox star, and Joba Chamberlain, once suspended for firing two fastballs over Youkilis’s head, evolved from a kindergarten spat compared with what went on between Carl Furillo and his longtime tormentor, the New York Giants right-hander Sal Maglie, before they suddenly became teammates on the Brooklyn Dodgers in 1956. In the first part of the 1950s, the Dodgers and the Giants won six consecutive National League pennants between them — the Dodgers four and the Giants two. They were raging rivals who, to be polite, didn’t like each other, and they demonstrated that dislike in 22 regular-season games every year. “Except for an occasional hello to Gil Hodges, when we’d walk past the Dodgers going to and from our clubhouses under the stands at Ebbets Field, I never spoke to any of them,” Bobby Thomson, whose home run won the 1951 pennant for the Giants, once said. “We just didn’t like each other.” Of all the Dodgers, Furillo, in particular, didn’t like the Giants. He didn’t like Leo Durocher, their manager. He didn’t like Maglie, the Giants ace known as Sal the Barber for how his pitches shaved opposing batters’ chins.1. Field of the Invention This invention relates to a method of taping a harness comprising a bundle of cables, and a machine therefor. 2. Summary of the Prior Art In French patent application FR 2 707 828, a method and apparatus for making a harness comprising electrical wires or other types of wires is described. The method described in the latter patent is particularly adapted for linear harness making machines comprising conveyor systems arranged in a straight line, that transport the harness therealong for processing. In the latter patent, the method is particularly concerned with manufacturing of a complex harness with a number of branches leading to various connection ends, where branches are held together at their joining points or nodes. In order to neatly branch off wires at a node, the harness is taped or tied at the nodes. Long sections of wires between nodes are however not held together, although the harness could be taped at intermediate positions between the nodes. It is however desirable in certain applications to keep the wires bundled together along the whole length between nodes, as exposed individual wires can get: caught on external objects. It may also be desirable to tape the whole harness with a protective layer to prevent damage to individual wires. In the event that taping of the whole harness is desired, it is typical to take a harness, for example which is prepared by the method in the above mentioned patent, or which is manufactured manually on a wiring board, and transport the harness to a taping machine. A known taping device 10 is shown in FIGS. 1a and 1b. The device comprises a static support 1 with a bearing 6, within which a large wheel 2 is rotatably mounted, further comprising a tape roll 3 mounted on an axis 7 pivotally to the wheel 2 and comprising a tape 5. The tape is spiralled around a section 4 of harness comprising a plurality of wires (not shown). The wheel 2 and support 1 have a U-shaped slot 8 to enable the harness section 4 to be positioned in alignment with the axis of the wheel. The wheel can then be rotated in the rotation direction R whilst the harness is fed in the axial direction such that the tape unrolls from the roll 3 and winds in a spiral around the harness. The section of harness to be taped, is supported typically by two grippers at either end, for example, positioned proximate nodes of the harness, the grippers being pulled apart to straighten the cable. The harness is manually fitted to the grippers, but the axial feeding and rotation of the wheel may be motor driven. The above method only enables a single section of harness between nodes to be taped, without intervention of an operator. An operator has to remove and reset the tape in the grippers when another section of the cable between different nodes, must be taped. This is a labour intensive and therefore costly procedure. Due to the complexity of certain harnesses with different numbers of nodes and branches and lengths of harness between the nodes, a solution for automating the taping procedure in a sufficiently simple and viable manner has not been found. Intervention of an operator to reposition the harness on the guides for each section of harness between nodes has the advantage of at least being a simple procedure with great flexibility (i.e. different cables can be easily treated in small production runs). A further problem of the prior method, is also the possibility of inconsistent quality and therefore in certain cases defects in the harness. It would however be desirable to render the harness making procedure less labour intensive, in a cost effective manner, whilst ensuring flexibility, simplicity and reliability of the harness making procedure. 234 S.C. 330 (1959) 108 S.E.2d
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Linked data is not just the purview of Library Land and a few computer scientists. Linked data has caught the attention of a much wider group of people, albiet the subject is still a bit esoteric. I know the technology supporting linked data functions. After all, it is the technology of the Web. I just wonder if: 1) there will ever be a critical mass of linked data available in order to fulfill its promise, and 2) will we — the information community — be able to overcome the “Tower of Babel” we are creating with all the the various ontologies we are sporting. A single ontology won’t work. Just look at Dublin Core. Many ontologies won’t work either. There is too much variation and too many idiosyncrasies in real-world human language. I don’t know what the answer is. I just don’t. Despite some of my misgivings, I think the following quote by Martin Malmsten pretty much sums up much of the conference — Linked data or die! One Response to “Semantic Web in Libraries 2013” PROV-O doesn’t offer much help for making provenance claims about named graphs and triples. The whole infrastructure is document oriented. You can use it to make claims about a serialized RDF document, but that doesn’t really handle the interesting use cases where knowledge about an entity is being formed from a number of different sources (indeed, where the number of different sources is part of the justification leg of the tripos). At the moment there is no specified mechanism for associating provenance with [the IRI associated with a named graph]. One possible approach might be to “push through” provenance assertions made about the IRI to virtual reified triples corresponding to the content; the details are tricky, and RDF reification is almost as annoying when it’s just pretend./* * Copyright (C) 2010 Pengutronix * Uwe Kleine-Koenig <u.kleine-koenig@pengutronix.de> * * This program is free software; you can redistribute it and/or modify it under * the terms of the GNU General Public License version 2 as published by the * Free Software Foundation. / #include <linux/dma-mapping.h> #include <asm/sizes.h> #include <mach/mx28.h> #include <mach/devices-common.h> #define mxs_fec_data_entry_single(soc, _id) \ { \ .id = _id, \ .iobase = soc ## _ENET_MAC ## _id ## _BASE_ADDR, \ .irq = soc ## _INT_ENET_MAC ## _id, \ } #define mxs_fec_data_entry(soc, _id) \ [_id] = mxs_fec_data_entry_single(soc, _id) #ifdef CONFIG_SOC_IMX28 const struct mxs_fec_data mx28_fec_data[] __initconst = { #define mx28_fec_data_entry(_id) \ mxs_fec_data_entry(MX28, _id) mx28_fec_data_entry(0), mx28_fec_data_entry(1), }; #endif struct platform_device __init mxs_add_fec( const struct mxs_fec_data data, const struct fec_platform_data pdata) { struct resource res[] = { { .start = data->iobase, .end = data->iobase + SZ_16K - 1, .flags = IORESOURCE_MEM, }, { .start = data->irq, .end = data->irq, .flags = IORESOURCE_IRQ, }, }; return mxs_add_platform_device_dmamask("imx28-fec", data->id, res, ARRAY_SIZE(res), pdata, sizeof(pdata), DMA_BIT_MASK(32)); } <!--\|This file generated by command(leetcode description); DO NOT EDIT. \|--> <!--+----------------------------------------------------------------------+--> <!--\|@author openset <openset.wang@gmail.com> \|--> <!--\|@link https://github.com/openset \|--> <!--\|@home https://github.com/openset/leetcode \|--> <!--+----------------------------------------------------------------------+--> [< Previous](../reverse-string "Reverse String") 　　　　　　　　　　　　　　　　 [Next >](../moving-average-from-data-stream "Moving Average from Data Stream") ## [345. Reverse Vowels of a String (Easy)](https://leetcode.com/problems/reverse-vowels-of-a-string "反转字符串中的元音字母") <p>Write a function that takes a string as input and reverse only the vowels of a string.</p> <p><strong>Example 1:</strong></p> <pre> <strong>Input: </strong><span id="example-input-1-1">"hello"</span> <strong>Output: </strong><span id="example-output-1">"holle"</span> </pre> <div> <p><strong>Example 2:</strong></p> <pre> <strong>Input: </strong><span id="example-input-2-1">"leetcode"</span> <strong>Output: </strong><span id="example-output-2">"leotcede"</span></pre> </div> <p><b>Note:</b><br /> The vowels does not include the letter "y".</p> <p> </p> ### Related Topics [[Two Pointers](../../tag/two-pointers/README.md)] [[String](../../tag/string/README.md)] ### Similar Questions 1. [Reverse String](../reverse-string) (Easy) 1. [Remove Vowels from a String](../remove-vowels-from-a-string) (Easy) #ifndef _TRANSFORM_TEST_DATA_H_ #define _TRANSFORM_TEST_DATA_H_ /--------------------------------------------------------------------------------/ / Includes / /--------------------------------------------------------------------------------/ #include "arr_desc.h" #include "arm_math.h" /--------------------------------------------------------------------------------/ / Macros and Defines / /--------------------------------------------------------------------------------/ #define TRANSFORM_MAX_FFT_LEN 4096 #define TRANFORM_BIGGEST_INPUT_TYPE float32_t /--------------------------------------------------------------------------------/ / Variable Declarations / /--------------------------------------------------------------------------------/ / Lengths are multiplied by 2 to accomodate complex numbers/ extern float32_t transform_fft_output_fut[TRANSFORM_MAX_FFT_LEN 2]; extern float32_t transform_fft_output_ref[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_input_fut[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_input_ref[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_output_f32_fut[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_output_f32_ref[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t * transform_fft_inplace_input_fut; extern float32_t * transform_fft_inplace_input_ref; extern float32_t transform_fft_f32_inputs[TRANSFORM_MAX_FFT_LEN * 2]; extern q31_t transform_fft_q31_inputs[TRANSFORM_MAX_FFT_LEN * 2]; extern q15_t * transform_fft_q15_inputs; extern q15_t dct4_transform_fft_q15_inputs[TRANSFORM_MAX_FFT_LEN * 2]; /* FFT Lengths */ ARR_DESC_DECLARE(transform_radix2_fftlens); ARR_DESC_DECLARE(transform_radix4_fftlens); ARR_DESC_DECLARE(transform_rfft_fftlens); ARR_DESC_DECLARE(transform_rfft_fast_fftlens); ARR
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]	"><span style="color: #006600;"><span style="color: black;"></span></span></div><div align="justify"><span style="color: #006600;"><span style="color: black;"></span></span></div><div align="justify"><span style="color: #006600;"><span style="color: black;">5. Now this is the moment of truth!! With a knife cut the pudding from the side of the baking pan. Put a nice big plate on top of the bunt backing pan and turn it upside-down and leave it for a while. Don't mess with it, just let the pudding slowly on its own fall down to the plate. If you mess with it it will brake and you will have an ugly pudding. It will fall, trust me and then there it is you beautiful delicious traditional Brazilian pudding. Very very yummy....specially very cold!</span></span><br /></div><div align="justify"><span style="color: #006600;">Agora e o momento da verdade. Com um faca descole as laterais da panela. Num prato grande coloque-o em cima da panela do pudim e vir-o de cabeca para baixo para desformar. Deixe ele cair sozinho, nao bata na panela pois vc pode quebraro pudim e ai vc tem uma meleca de caramelo. Deixe o pudim cair sozinho. E quando ele cair vc tera um lindo pudim com furrinhos que e uma delicia!</span></div><br /><br /><div align="center"><br /><embed flashvars="host=picasaweb.google.com&RGB=0x000000&feed=http%3A%2F%2Fpicasaweb.google.com%2Fdata%2Ffeed%2Fapi%2Fuser%2Fglitterlife.nl%2Falbumid%2F5289133589769511697%3Fkind%3Dphoto%26alt%3Drss" height="267" pluginspage="http://www.macromedia.com/go/getflashplayer" src="http://picasaweb.google.com/s/c/bin/slideshow.swf" type="application/x-shockwave-flash" width="400"></embed> </div>Alexhttp://www.blogger.com/profile/04983060725228328421noreply@blogger.com1tag:blogger.com,1999:blog-5910967346863755132.post-41667541535255064692009-01-01T13:56:00.002+11:002009-01-01T14:28:54.608+11:00Happy New Year!!!!<div align="justify"><a href="http://1.bp.blogspot.com/_N8Lmem60GXk/SVw4SMyyk0I/AAAAAAAALzw/zsDsd66rFDU/s1600-h/IMG_5029.JPG"><img id="BLOGGER_PHOTO_ID_5286161947949175618" style="FLOAT: left; MARGIN: 0px 10px 10px 0px; WIDTH: 150px; CURSOR: hand; HEIGHT: 200px" alt="" src="http://1.bp.blogspot.com/_N8Lmem60GXk/SVw4SMyyk0I/AAAAAAAALzw/zsDsd66rFDU/s200/IMG_5029.JPG" border="0" /></a> We had such a great time last night at Paul's house. It was strange but wonderful to have the passage of the New Year outside having a barbecue in a warm summer night. The memories of when we had our New Year parties in Brazil was present throughout the evening for me. I had very nice fish with some very yummy salad and lots and lots of water and soda. The picture posted on the blog is just for fun....Rob and Paul were smoking cigars and we thought it would be fun to take picture with me with the cigar and beer... so for all of you out there I did not smoke a cigar or drank beer this New Year!!! It was great to be among friends and family and everyone really had a wonderful time. Alice was really enjoying the warm weather and the great food. It really was a perfect evening for all of us! I wish all of you a great 2009 and that this year will bring peace, joy and happiness for all of you who read my blog. Enjoy the slide show...<br /><br /><embed pluginspage="http://www.macromedia.com/go/getflashplayer" src="http://picasaweb.google.com/s/c/bin/slideshow.swf" width="400" height="267" type="application/x-shockwave-flash" flashvars="host=picasaweb.google.com&captions=1&RGB=0x000000&feed=http%3A%2F%2Fpicasaweb.google.com%2Fdata%2Ffeed%2Fapi%2Fuser%2Fglitterlife.nl%2Falbumid%2F5286153427089127857%3Fkind%3Dphoto%26alt%3Drss"></embed><br /></div>Alexhttp://www.blogger.com/profile/04983060725228328421noreply@blogger.com0AC Repair Has your AC unit stopped working? Of course, the Lowcountry summer is officially upon us and that air conditioning unit you’ve forgotten about all winter isn’t cooperating. Well, look no further than Brian’s Mechanical LLC – we’re here to solve your problems! Whether your air conditioning unit has stopped blowing that icy cold air you love so much, or just stopped working at all, Brian’s Mechanical LLC is here serving your AC repair needs. Specializing in commercial and residential HVAC issues Brian’s Mechanical LLC serves the Tricounty area 24 hours a day and 7 days a week.Publisher's Summary Belle Marshall has no desire to be a traditional wife. As the town healer and manager of the boardinghouse, independence is hers; a husband will only get in the way. Still, she's finding Paul Harrington, the local preacher, harder and harder to ignore each day. How can she stop their emerging romance before it begins? Paul Harrington has given up his violent past as a Texas Ranger and turned a new leaf as the town preacher. Still, it's a constant battle to keep his former self from surfacing. Belle Marshall is just the match to set fire to the tinderbox of passions in his heart, but how can he let her in, while keeping the rest of his emotions in check? Belle and Paul will just have to keep apart. But will the rest of the townspeople let them?(* ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ ) ( :Title: SUNTrace ) ( :Author: Rolf Mertig ) ( ------------------------------------------------------------------------ ) ( :History: File created on 21 March '98 at 9:07 ) ( ------------------------------------------------------------------------ ) ( :Summary: calculation of traces of SUNT-matrices (color factors)) ( ------------------------------------------------------------------------ ) SUNTrace::usage= "SUNTrace[exp] calculates the color-trace."; ( ------------------------------------------------------------------------ ) Begin["`Package`"] End[] Begin["`SUNTrace`Private`"] Options[SUNTrace] = { Explicit -> False }; HoldPattern[SUNTrace[n_, ___Rule]] := SUNN n /; FCPatternFreeQ[{n}, {SUNT}]; ( this is the function which puts everything together ********* ) SUNTrace[expr_Plus, op___Rule] := Map[SUNTrace[#, op]&, expr]; (new; suggested by Frederik Orellana ) SUNTrace[expr_Times,op___Rule] := (Select[expr, FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&] SUNTrace[Select[expr,!FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&], op])/; (expr === fcis[expr]) && (Select[expr,!FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&] =!= 1) && (To avoid infinite recursion. 3/9-2002. Frederik Orellana) (Select[expr, FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&] =!= 1); HoldPattern[SUNTrace[1.., ___Rule]] = SUNN; HoldPattern[SUNTrace[a_, ___Rule]] := 0 /; MatchQ[a, SUNT[SUNIndex[_]]] && nopat[a] && (fcis[a] === a);
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0.205636 vt 0.002584 0.200554 vt 0.704966 0.197368 vt 0.701120 0.995284 vt 0.714273 0.984982 vt 0.698392 0.805061 vt 0.698392 0.995441 vt 0.006986 0.804890 vt 0.003140 0.993250 vt 0.997806 0.984982 vt 0.002194 0.794603 vt 0.009714 0.205698 vt 0.990286 0.995440 vt 0.698392 0.794542 vt 0.003140 0.802872 vt 0.006986 0.995284 vt 0.002120 0.211502 vt 0.993014 0.995268 vt 0.714664 0.990064 vt 0.002121 0.979116 vt 0.009714 0.195178 vt 0.704966 0.993250 vt 0.705912 0.205636 vt 0.715219 0.993250 vt 0.006905 0.199752 vt 0.004622 0.196175 vt 0.716701 0.994443 vt 0.996860 0.993250 vt 0.703484 0.196175 vt 0.002584 0.799686 vt 0.715219 0.006750 vt 0.701120 0.195349 vt 0.009714 0.995441 usemtl Material s 1 f 5/1 1/2 4/3 6/4 f 47/5 51/6 52/7 f 9/8 6/4 4/3 8/9 f 49/10 48/11 54/12 60/13 f 11/14 7/15 17/16 14/17 f 42/18 49/10 60/13 59/19 f 28/20 27/21 73/22 67/23 f 8/9 2/24 7/15 9/8 f 18/25 22/26 23/27 f 12/28 9/8 7/15 11/14 f 5/1 10/29 40/30 37/31 f 11/14 3/32 10/29 12/28 f 13/33 20/34 25/35 24/36 f 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30, 5388, 1352, 187, 187, 3138, 46218, 456, 5788, 9191, 407, 473, 7858, 285, 407, 353, 1843, 16943, 2203, 14, 1968, 568, 926, 27, 911, 793, 321, 2648, 46, 10148, 14102, 36, 64, 3549, 86, 64, 16854, 15, 42787, 910, 3429, 568, 1438, 15, 9439, 20868, 187, 187, 4509, 5317, 575, 1447, 926, 27, 911, 793, 321, 2648, 46, 696, 359, 923, 326, 253, 1878, 19325, 29107, 285, 253, 4869, 12177, 29107, 1918, 2074, 8197, 273, 253, 5788 ]	8 \beta_0 -5\beta_1 -6 \beta_2.$$ In this case, the domain is defined by the matrix $\mathbf{M_D} = \begin{pmatrix} 1 & 0 & 0 \\ 1 & 0 & 1 \\ 1 & 1 & 0 \\ 1 & 1 & 1 \\ \end{pmatrix}$, yielding the boundary conditions $\mathbf{M_D} \boldsymbol{\beta} \geq 0$. Let $\gamma_0 = \beta_0 + \beta_2$, then we can substitute $\beta_0$ by $\gamma_0$ in Equation , obtaining $\ell^* = \log \gamma_0 - 8 \gamma_0 -5\beta_1 + 2 \beta_2$. By Proposition \[prop:maximumpointReverse\], we know that the maximum point must lie in the intersection of two flat boundaries defined by the row vectors of matrix $M_\mathbf{D}$. For step 1 in Algorithm 1 we need to select two other rows from $\mathbf{M_D}$ which, together with $\mathbf{x}$, form an invertible basis matrix $\mathbf{B}$. Denote the $j^{\textrm{th}}$ row of $\mathbf{M_D}$ as $M_j$. Since $\mathbf{x}$ itself corresponds to the second row of $\mathbf{M_D}$, that leaves as possibilities for the second and third row of $\mathbf{B}$: $M_1$ and $M_3$, $M_1$ and $M_4$, and $M_3$ and $M_4$. Of these, calculating $\mathbf{r} = \mathbf{B}^{-1} \mathbf{s}$, we see that $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_1 \| M_3 \end{pmatrix}^\top$ yields $\mathbf{r} = (6, -3, 5)^\top$, $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_1 \| M_4 \end{pmatrix}^\top$ yields $\mathbf{r} = (1, 2, 5)^\top$, and $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_3 \| M_4 \end{pmatrix}^\top$ yields $\mathbf{r} = (3, 2, 3)^\top$. By proposition (\[prop:maximumpoint\]), we demand $\mathbf{r} \geq 0$. That leaves only the combinations $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_1 \| M_4 \end{pmatrix}^\top$ and $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_3 \| M_4 \end{pmatrix}^\top$ as valid combinations after the first step. The next step is to check whether the corresponding $\mathbf{\beta}$ estimates satisfy the boundary conditions. The first remaining option, $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_1 \| M_4 \end{pmatrix}^\top = \begin{pmatrix} 1 & 0 & 1 \\ 1 & 0 & 0 \\ 1 & 1 & 1 \\ \end{pmatrix}$, gives $\mathbf{r} = \begin{pmatrix} 1 \\ 2 \\ 5 \\ \end{pmatrix}$, and $\boldsymbol{\gamma} = \begin{pmatrix} 1 \\ 0 \\ 0 \\ \end{pmatrix}$. The corresponding value of $\mathbf{\beta}$ is given by $\boldsymbol{\beta} = \mathbf{B}^{-1} \boldsymbol{\gamma} = \begin{pmatrix} 0 \\ -1 \\ 1 \\ \end{pmatrix}$, with $\ell^* = -1$. Checking the boundary conditions $\mathbf{M_D} \boldsymbol{\beta} \geq 0$ yields $\mathbf{M_D} \boldsymbol{\beta} = (0, 1, -1, 0)^\top$, a violation for the third row of $\mathbf{M_D}$, so that $\boldsymbol{\beta}$ is not in $\mathbf{D}$ and this solution is not admissible. In our search we would then look for bases including the third row. This coincides with our second remaining option, $\mathbf{B} = \begin{pmatrix} \mathbf{x} \| M_3 \| M_4 \end{pmatrix}^\top = \begin{pmatrix} 1 & 0 & 1 \\ 1 & 1 & 0 \\ 1 & 1 & 1 \\ \end{pmatrix}$, which gives $\mathbf{r} = \begin{pmatrix} 3 \\ 2 \\ 3 \\ \end{pmatrix}$, and $\boldsymbol{\gamma} = \begin{pmatrix} 1/3 \\ 0 \\ 0 \\ \end{pmatrix}$. The corresponding value of $\mathbf{\beta}$ is given by $\boldsymbol{\beta} = \mathbf{B}^{-1} \boldsymbol{\gamma} = \begin{pmatrix} 1/3 \\ -1/3 \\ 0 \\ \end{pmatrix}$, with $\ell^* = -\log(3) - 1$, which is smaller than the previous value. Checking the boundary conditions $\mathbf{M_D} \boldsymbol{\beta} \geq 0$ yields $\mathbf{M_D} \boldsymbol{\beta} = (1/3, 1/3, 0, 0)^\top$, which is $\geq 0$, so this is the maximum point we want to find. We comment that it is not necessary in step $1$ to find all the valid $\mathbf B$ which yields positive $\mathbf r$ in practice. It is sufficient to find one $\mathbf B$ and go to the next step. We show all the possible $\mathbf B$ of step $1$ in this example just to give a full picture of this algorithm. Simulation {#sec:simulation} ========== The purpose of the simulation study is to show feasibility of our maximum likelihood estimator and compare its performance with the OLS estimator. In our experiment, we assume $\boldsymbol \beta(t) = (0.05,0.02,0.04,0.06,0.08)t$, hence the true hazard $h$ is given by: $$h(t \,\|\, \mathbf{x}) = \sum_i \beta_i x_i t= (0.05 + 0.02\ x_1 + 0.04\ x_2 + 0.06 \ x_3 +0.08\ x_4)t.$$ This corresponds to a Weibull distribution with shape $b=2$ and rate $a = (0.05 + 0.02 x_1 + 0.04 x_2 + 0.06 x_3 + 0.08 x_4) / 2$, using the parametrization for the Weibull hazard $h(t; a, b) = a b t^{b-1}$. We started by randomly generating covariate data $\mathbf{x}_i$, for $i=1,\ldots, n$, with $n=500$, with independent uniform distributions on $[0, 1]$. Then, given covariate data $\mathbf{x}_i$, we generated times to event $T_i^$ according to a Weibull distribution with shape $b=2$ and rate $a = (0.05 + 0.02 x_1 + 0.04 x_2 + 0.06 x_3 + 0.08 x_4) / 2$. For each subject an independent censoring time $C_i$ was generated with uniform distribution over $(2.5,7.5)$, giving a censoring rate of about $22\%$. The observed data are given by event time $t_i = \min(t_i^, c_i)$, status indicator $\delta_i = I(t_i^* \leq c_i)$, and covariate vector $\mathbf{x}_i$. Two methods are implemented in this experiment to estimate $\boldsymbol{\beta}$: Aalen’s OLS method described in Section \[sub:OLS\], as implemented in the timereg package [@martinussen2007dynamic] and the maximum likelihood estimator with domain $\mathbf D$ as we have introduced in Section \[sub:ML\]. We used the estimated $\boldsymbol{\beta}$ to calculate the survival curve without any smoothness. We choose a subject with data of values $x = (0.4,0.6,0.4,0.6)$. Thus the hazard rate of this subject is $$h(t) = (\beta_0(t) + \beta_1(t) 0.4 + \beta_2(t) 0.6 +\beta_3(t) 0.4+\beta_4(t) 0.6)$$ Figure \[fig:expsurCCM\] shows the true survival curve and the estimated survival curves by the two methods, for the first data set of size $n=500$. ![Estimated survival curves by OLS and by MLE[]{data-label="fig:expsurCCM"}](SurC_simu_TG.jpeg){width="80.00000%"} From Figure \[fig:expsurCCM\] we see that the least squares estimator and the maximum likelihood estimator give similar estimates of the survival
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17, 94, 393, 700, 92, 76, 94, 559, 362, 578, 90, 1603, 89, 13, 91, 13, 85, 10, 393, 700, 92, 75, 94, 393, 6274, 3353, 187, 50276, 61, 11765, 92, 35, 94, 14082, 378, 578, 17, 89, 1603, 89, 13, 91, 10, 393, 700, 92, 74 ]	the most recent items in the beginning, maybe categorize it too, and then you can use expandable listview to enhance more the pick item process per category. What's Not Included Travel Insurance Tips for staff Miscellaneous expenses - drinks and souvenirs etc. Meal Plan All meals are included from dinner on day 1 to breakfast on day 8. Accommodation During this holiday the group will spend 2 nights at a comfortable family orientated hotel in Marrakech. This hotel has great gardens to run around in and a swimming pool. In the mountains we stay in a simple gite for 2 nights, which has family rooms with mattresses on the floor. Bedding is provided here but we advise you to take a sheet sleeping bag. In March and October you may also wish to bring a light sleeping bag to supplement the blankets. Rooms in the gite have shared facilities. In Essaouria, we will stay 3 nights in a small hotel with swimming pool just a short distance from the Medina and 2 minutes walk from the beach. Children of 11yrs and under will share with parents in a triple for a family of 3 or a double with 2 extra beds for a family of 4. Children over 12 yrs will share with parents in a triple for a family of 3, or have 2 rooms for a family of 4. Larger family rooms are occasionally available. We will do everything to ensure that you are happy with your rooming allocation. Additional hotel nights are available pre and post the holiday. Hotels are subject to availability and prices may vary.Change Is Never Easy, but It Is Possible: Reflections on Avoidant/Restrictive Food Intake Disorder Two Years After Its Introduction in the DSM-5. One of the most significant changes to the section on Feeding and Eating Disorders in the DSM-5 was that feeding disorder of infancy or early childhood was renamed avoidant/restrictive food intake disorder or ARFID, and the criteria was significantly expanded. This diagnostic category was informed by field studies, analysis, and expert opinion. To date, research exploring the prevalence, clinical characteristics and utility have helped substantiate the recognition and need for the diagnostic category of AFRID as a distinct eating disorder diagnosis in the DSM-5.--- abstract: 'The excitation of Alfvénic waves in the solar spicules due to the localized Alfvénic pulse is investigated. A set of incompressible MHD equations in two dimensional $x-z$ plane with steady flows and sheared magnetic fields is solved. Stratification due to gravity and transition region between chromosphere and corona are taken into account. An initially localized Alfvénic pulse launched below the transition region can penetrate from transition region into the corona. We show that the period of transversal oscillations is in agreement with those observed in spicules. Moreover, it is found that the excited Alfvénic waves spread during propagation along the spicule length, and suffer efficient damping of the oscillations amplitude. The damping time of transverse oscillations elongated with decrease in $k_{b}$ values.' author: - 'H. Ebadi' - 'M. Hosseinpour' - 'Z. Fazel' title: Transverse oscillations in solar spicules induced by propagating Alfvénic pulses --- Introduction {#sec:intro} ============ Spicules are one of the most fundamental components of the solar chromosphere. They are seen in chromospheric spectral lines at the solar limb at speeds of about $20-25$ km s$^{-1}$ propagating from the chromosphere into the solar corona [@Tem2009]. Their diameter and length varies from spicule to spicule having the values from $400$ km to $1500$ km and from $5000$ km to $9000$ km, respectively. The typical lifetime of them is $5-15$ min. The typical electron density at heights where the spicules are observed is approximately $3.5\times10^{16}-2\times10^{17}$ m$^{-3}$, and their temperatures are estimated as $5000-8000$ K [@bec68; @ster2000]. @Kukh2006 [@Tem2007] by analyzing the height series of $H\alpha$ spectra in solar limb spicules observed their transverse oscillations with the estimated period of $20-55$ and $75-110$ s. More recently, @Ebadi2012a based on Hinode/SOT observations estimated the oscillation period of spicule axis around $180$ s.\ Despite the large body of theoretical and observational works devoted to the spicules, their ejection mechanism is not clear yet. In other words, observations with high spatial resolutions are needed to distinguish their origin. The Alfvén waves are usual candidates for energy transport from the lower layers of the solar atmosphere to the corona [@De2007; @Tsiklauri2002]. @Hollweg1982 showed that the Alfvén waves may be nonlinearly coupled to fast magnetoacoustic shocks, which may lead to spicule formation. @Cargill1997 performed the numerical simulations of the propagation of Alfvénic pulses in two dimensional magnetic field geometries. They concluded that for an Alfvénic pulse the time at which different parts of the pulse emerge into the corona depends on the plasma density and magnetic field properties. Moreover, they discussed that this mechanism can interpret spicule ejection forced through the transition region. @Kudoh1999 used the random nonlinear Alfvénic pulses and concluded that the transition region lifted up to more than $\sim5000$ km (i.e. the spicule produced). @Del2005 studied the propagation and evolution of Alfvénic pulses through coronal arcades. Their results showed a strong spreading of the initially localized pulses due to variations of Alfvén speed with height and efficient damping of oscillations. In addition, they concluded that the background density and Alfvén speed should be considered as key ingredients in models. @Tem2010 studied the upward propagation of a velocity pulse launched initially below the transition region. The pulse quickly steepens to a shock which may form the spicules. They concluded that such a model may explain speed, width, and heights of classical spicules. @Rae1982 illustrated that impulsive motions may propagate along an intense tube. Information (in the form of a wave front) propagates at the subsonic and subAlfvénic tube speed. As the wave front of an impulsively generated disturbance propagates along the tube, it trails behind it a wake, which oscillates at cut-off frequency. The significance of cut-off frequency depends upon what are the circumstances creating the motions. If disturbances are impulsively generated, then wave propagation occurs and the existence of cut-off frequency is manifest in the creation of an oscillatory wake. @Hasan1999 examined the generation of waves in vertical flux tubes in the magnetic network through the impulsive excitation by granules. The buffering action of a granule on a flux tube at a certain level excites a pulse that travels away from the source region with tube speed. After the passage of the pulse, the atmosphere oscillates at the cut-off period of the mode, with amplitude that slowly decays in time. @Tem2008 concluded that photospheric granulation may excite transverse pulses in anchored vertical magnetic flux tubes. The pulses propagate upward along the tubes while oscillating wake is formed behind the wave front in a stratified atmosphere. The pulses carry almost all the energy of initial perturbations, while the energy in wake oscillations is much smaller.\ In the present work we perform two-dimensional simulations of MHD equations and show that the Alfvénic pulse which is launched below the transition region can excite Alfvén waves and reach the height where spicules are observed. Section $2$ gives the basic equations and theoretical model. In section $3$ numerical results are presented and discussed, and a brief summary is followed in section $4$. Theoretical modeling {#sec:theory} ==================== We keep effects of stratification due to gravity in $2$D x-z plane in the presence of steady flow and shear field. Since the excitation of incompressible Alfvén waves due to Alfvénic pulses is the main goal of this work, so the continuity and energy equations are not considered. The ideal MHD equations used are as follows: $$\label{eq:momentum} \rho(\frac{\partial \mathbf{v}}{\partial t}+ \mathbf{v} \cdot \nabla\mathbf{v}) = -\nabla p + \rho \mathbf{g}+ \frac{1}{\mu}(\nabla \times \mathbf{B})\times \mathbf{B},$$ $$\label{eq:induction} \frac{\partial \mathbf{B}}{\partial t} = \nabla \times(\mathbf{v} \times \mathbf{B}),$$ $$\label{eq:state} p = \frac{\rho RT}{\mu}.$$ Here, $\rho$ is the plasma density; $T$ is the plasma temperature in Kelvin; $R$ is the universal gas constant, and $\mu$ is the mean molecular weight. We assume that the spicules are highly dynamic with speeds that are significant fractions of the Alfvén speed. Perturbations are assumed independent of y, i.e.: $$\begin{aligned} \label{eq:perv} \textbf{v} &=& v_{0} \hat{k} + v_{y}(x,z,t) \hat{j} \nonumber\\ \textbf{B} &=& B_{0x}(x,z) \hat{i
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15, 20676, 25988, 273, 14857, 14, 1637 ]	& 168 & $<$0\ 1.0 & 331 & $<$0\ 1.5 & 723 & $<$0\ 2.0 & 1231 & $<$0\ 3.0 & 2470 & $<$0\ \[tab:f\] [l c c c c c]{} Miras & 11.4$^{\mathrm{a,b}}$ & 10$^{-9}$ & $<$40%$^{\mathrm{d}}$ & $1.14 \times 10^{-8}$ & $<$0.2%\ OH/IR stars & 1.1$^{\mathrm{a,b}}$ & 10$^{-6}$ & 10%$^{\mathrm{d}}$ & $1.1 \times 10^{-6}$ & 4–5%\ M Supergiants & 1–2$^{\mathrm{c}}$ & 10$^{-6}$ & 15–20%$^{\mathrm{e}}$ & $1-2 \times 10^{-6}$ & 7–13%\ Supernovae & n/a & n/a &? & $\sim 4 \times 10^{-7}$ $^ {\mathrm{f}}$&?\ \[tab:injection\] [^1]: Based on observations with ISO, an ESA project with instruments funded by ESA Member States (especially the PI countries: France, Germany, the Netherlands and the United Kingdom) and with the participation of ISAS and NASA Well, that was disgusting! I was in the barn last night, topping up water buckets for the goats. I checked the buck's pail for "berries" and saw a dead rat floating in it. So... I hauled it out, went outside to dump it and poured off some of the water, so it wouldn't be so heavy to carry to a good spot. I see another dead rat! I poured some more water out, and there was a third dead rat in the bucket. Makes me wonder how many more of the buggers I've got in the barn. :grump: Those kittens better get working or I'll take them back as defective. Please tell me your secret!! If I could get 3 Rats in one night without a shotgun and a spotlight I'd be in heaven. Evening intertainment for us is shooting the dumb young ones off the roof of the old shack that was here when we bought the place. Planned to use it for storage but so did they!!!. Dave & Chris in NE Washington State I'm in Northern Ontario and we are having an outbreak of rats in town. It's made the front page of the local paper the last two weeks. I dislike mice and rats are enough to make me completely loopy. Click to expand... Several years ago when we were still on LI, we had an outbreak of mice. They were EVERYWHERE! Even the exterminator across the street and my clean freak friend next door (with 3 cats!) couldn't get rid of them. Even at church, you would be praying at the altar and glance down and a little church mouse would be sashaying by! I wish I had the right kind of gun to blast the bugger that keeps coming and going out of our house. We've had a trap set for almost five days now and the rat by passes it and goes into my bedroom to rip of my socks I've took off that day. I'm missing a pair of socks (taken one night) and one sock from another pair (taken the next night). :grump: Blasted rats! I don't know how the critter is coming and going in and out of the house. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. I wish I had the right kind of gun to blast the bugger that keeps coming and going out of our house. We've had a trap set for almost five days now and the rat by passes it and goes into my bedroom to rip of my socks I've took off that day. I'm missing a pair of socks (taken one night) and one sock from another pair (taken the next night). :grump: Blasted rats! I don't know how the critter is coming and going in and out of the house. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. Click to expand... somewhere along your foundation there is probably a crack or a hole where he gets in. the may also be a hole in the wall behind a piece of furniture. they don't need much of a crack or hole to get in and out. I wish I had the right kind of gun to blast the bugger that keeps coming and going out of our house. We've had a trap set for almost five days now and the rat by passes it and goes into my bedroom to rip of my socks I've took off that day. I'm missing a pair of socks (taken one night) and one sock from another pair (taken the next night). :grump: Blasted rats! I don't know how the critter is coming and going in and out of the house. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. We've had a bad rat problem this year, too. And I mean RATS--big 'ol rats! First they were in the calf barn and around the dog kennels. Ramik bar bait works wonders. It's sort of expensive, but it works. Not by me, they're not! I would never put poison down, with goats, kittens and free-range hens. I've got two little Nigerian Dwarf doelings who can squeeze out of their pen, and the kittens can get anywhere too. I can't see that they'd come all the way from the neighbours just to drink out of my buckets - there's a couple of creeks between us. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. Click to expand... Four goat pens - four water buckets. Plus rainbarrels and rain bathtubs. I think the rats have enough choice. Hey, I already invented a better mousetrap - take a 5 gallon pail, put about an inch of oats in the bottom. Mice jump in to get grain, can't get a grip to jump out - take cat and hold him so he can grab the mice! Even with all those critters, you could still use bar bait poison. The thing is, you just have to put it in something that the rats can get to, but the animals can't. Example, you could nail the bar bait to a stick of wood and put it in a 4" diameter pipe, at least a yard long. The rats can't hoard it to a place that the animals can get to--they have to eat it on the spot. That diameter pipe ought to be small enough that the kittens can't squeeze into. Now goats, I don't know much about goats. You might have to be more creative to put it somewhere they can't get into. But bar bait is great because you can nail it to something or string it on a wire, i.e., secure it in place so it won't go places you don't intend it to.Q: Registering application to handle USB device attachment I want to add my application to the list of apps Android offers to launch when a digital camera is connected. I've added this to my manifest: <intent-filter> <action android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" /> <meta-data android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" android:resource="@xml/device_filter" /> </intent-filter> And specified a filter (class 6 is digital camera, but I've tried empty filter as well): <resources> <usb-device class="6"/> </resources> It has no effect, my app is still not in that list. What else do I have to do? Note that I'm not interested in the broadcast intent, all I need is to make it to the list of choices for handling the device user is presented with. A: Found the problem. Manifest should be like this: <intent-filter> <action android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" /> </intent-filter> <meta-data android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" android:resource="@xml/device_filter" /> I. e. meta-data shouldn't be sub-element of intent-filter like I've put it. Increased TNF-alpha and PGI(2), but not NO release from macrophages in 18-month-old rats. TNF-alpha is an important pro-inflammatory mediator that influences host defense against infection and cancer. Previous examinations of TNF-alpha
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342, 773, 423, 606, 2158, 3872, 3988, 949, 23306, 1411, 253, 985, 285, 17985, 49093, 323, 34550, 1806, 271, 20533, 18082, 753, 1905, 8505, 984, 273, 617, 789, 26169, 11073, 27691, 273, 20533, 285, 530, 15, 52, 15, 10071, 15, 187, 187, 4967, 1057, 7751, 457, 84, 9550, 513, 824, 247, 2181, 32 ]	success are long. STEPHEN BIDDLE: If I had to put a number to it, maybe it’s a one in ten. Maybe it’s a one in five longshot, if we play our cards right. There’s no question that this is likelier to fail than succeed at this point. DAVID MARTIN: In an effort to wipe out insurgent strongholds, U.S. troops will be moving into parts of Baghdad and the surrounding countryside, where they have never been before. But even with the surge, former marine Bing West says, there aren’t enough troops to chase insurgents all over Iraq. BING WEST: The insurgents move 60 to 100 kilometers in a night. And all of Iraq is so flat, has such terrific highways, that you can scoot very quickly from place to place. MARTIN: According to Biddle, success depends on coercing insurgent factions into accepting a cease fire. BIDDLE: 160,000 troops is not enough to secure the whole country. But it’s a powerful source of sticks and carrots. If we start using it selectively to reward those who cooperate and consider cease fires, and to punish those who don’t. MARTIN: There are cease fire negotiations going on with insurgents, but for now one military officer says, “there out to kill us, we’re out to kill them.” David Martin, CBS News, the Pentagon. ANKARA, Turkey - Turkey has sent large contingents of reinforcement soldiers, tanks and armored personnel carriers to its border with Iraq as debate heated up over whether to stage a cross-border offensive to hit Kurdish rebel bases. Prime Minister Recep Tayyip Erdogan on Tuesday urged the United States and Iraq to destroy bases of the Kurdistan Workers Party, or PKK, in northern Iraq as Turkish military deployed more tanks and soldiers on the border. The images of military trucks rumbling along the remote border with Iraq's Kurdish zone and tanks being transferred on trains and trucks to beef up an already formidable force there have occupied television screens and front pages of several newspapers in the last few weeks. The Turkish military has said it routinely reinforces the border with Iraq in the summer to prevent infiltrations by the guerrillas. "The PKK must be eliminated as a problem between Iraq and Turkey," Turkey's special envoy to Iraq, Oguz Celikkol, told CNN-Turk television on Wednesday before a visit to Iraq to discuss Turkish demands that Iraq and U.S. forces crack down on the group..... Tuesday, May 29, 2007 The odd thing is that conservatives wear pinstriped suits, when they really should be walking around in togas. The main contribution of the Greeks to modern American politics may have been Michael Dukakis, who once climbed the Acropolis in wingtips. But that doesn’t stop conservatives — especially the Straussians who pushed for going into Iraq — from being obsessed with ancient Greece, and from believing that they are the successors to Plato and Homer in terms of the lofty ideals and nobility and character in American politics — while Democrats merely muck about with policies for the needy. Harvey Mansfield, a leading Straussian who teaches political science at Harvard and who wrote a book called “Manliness” (he’s for it), gave the Jefferson lecture recently at the National Endowment for the Humanities in Washington. It was an ode, as his book is, to “thumos,” the Greek word that means spiritedness, with flavors of ambition, pride and brute willfulness. Thumos, as Philip Kennicott wrote in The Washington Post, “is a word reinvented by conservative academics who need to put a fancy name on a political philosophy that boils down to ‘boys will be boys.’ ” Mr. Mansfield did not mention the war, which is a downer at conclaves of neocons and thumos worshippers. But he explained that thumos is “the bristling reaction of an animal in face of a threat or a possible threat.” In thumos, he added, “we see the animality of man, for men (and especially males) often behave like dogs barking, snakes hissing, birds flapping. But precisely here we also see the humanity of the human animal” because it is reacting for “a reason, even for a principle, a cause. Only human beings get angry.” The professor used an example, naturally, from ancient Greece to explain why politics should be about revolution rather than equilibrium: “What did Achilles do when his ruler Agamemnon stole his slave-girl? He raised the stakes. He asserted that the trouble was not in this loss alone but in the fact that the wrong sort of man was ruling the Greeks. Heroes, or at least he-men like Achilles, should be in charge rather than lesser beings like Agamemnon who have mainly their lineage to recommend them and who therefore do not give he-men the honors they deserve. Achilles elevated a civil complaint concerning a private wrong to a demand for a change of regime, a revolution in politics.” Mr. Mansfield concluded: “To complain of an injustice is an implicit claim to rule.” The most recent example of the Hellenization of the Bush administration is the president’s choice for war czar, Army Lt. Gen. Douglas Lute, who says he loves the Greek military historian Thucydides. Other Thucydides aficionados include Victor Davis Hanson, who was a war-guru to Dick Cheney when the vice president went into the bunker after 9/11 and got into his gloomy Hobbesian phase. (Hobbes’s biggest influence was also Thucydides.) Donald Kagan, a respected Yale historian who has written authoritatively on the Peloponnesian War, is the father of Robert Kagan, a neocon who pushed for the Iraq invasion, and Frederick Kagan, a military historian who urged the surge. I called Professor Kagan to ask him if Thucydides, the master at chronicling hubris and imperial overreaching, might provide the new war czar with any wisdom that can help America sort through the morass of Iraq. Very much his sons’ father, the classicist said he was disgusted that the White House, after a fiasco of an occupation designed by Rummy, “is still doing one dumb thing after another” by appointing General Lute, a chief skeptic of the surge. Professor Kagan said that one reason the Athenians ended up losing the war was because in the Battle of Mantinea in 418 B.C. against the Spartans, they sent “a very inferior force” and had a general in command who was associated with the faction that was against the aggressive policy against the Spartans. “Kind of like President Bush appointing this guy to run the war whose strategy is opposed to the surge,” he said dryly. With cold realism, Thucydides captured the Athenian philosophy in the 27-year war that led to their downfall as a golden democracy: “The strong do what they can and the weak suffer what they must.” What message can we take away from Thucydides for modern times? “To me,” Professor Kagan said, “the deepest message, the most tragic, is his picture of civilization as a very thin veneer. When you punch a hole in it, what you find underneath is hollow, the precivilized characteristics of the human race — animalistic in the worst possible way.” I thought this regime was powerful and self-confident, and actually felt strengthened since we destroyed its two main enemies — the Taliban and Saddam. That could not be further from the truth. This Iranian regime is afraid of its shadow. How do I know? It recently arrested a 67-year-old grandmother, whom it accused of trying to bring down the regime by organizing academic conferences! Yes, big, tough President Mahmoud Ahmadinejad — the man who shows us how tough he is by declaring the Holocaust a myth — had his goons arrest Haleh Esfandiari, a 67-year-old scholar, grandmother and dual Iranian-U.S. citizen, while she was visiting her 93-year-old mother in Tehran. Do you know how paranoid you have to be to think that a 67-year-old grandmother visiting her 93-year-old mother can bring down your regime? Now that is insecure. It’s also shameful. Haleh directs the Middle East program of the Woodrow Wilson International Center for Scholars in Washington. She went to Iran in December to visit her aging mother — a trip she’s made regularly for the past decade. According to her husband, Shaul Bakhash, himself a renown Iran expert in the U.S., while Haleh was traveling to the Tehran airport on Dec. 30, to return home, she was stopped by three masked, knife-wielding men — Iran’s Intelligence Ministry always needs three men and three knives when confronting a grandmother — and they stole her belongings and her U.S. and Iranian passports. This was followed by six weeks of intermittent questioning by Iran’s Ministry of Intelligence. Then, on May 7, Haleh was arrested. Yesterday, she was formally charged with “endangering national security through propaganda against the system and espionage for foreigners,” an Iranian spokesman said — apparently because of her work organizing academic conferences of Iranian and U.S. experts. Why does Iran’s leadership do such a thing?
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2226, 15, 1707, 403, 1980, 313, 54, 12648, 10, 11967, 285, 5213, 11967, 824, 347, 26564, 4899, 13, 329, 2025, 1322, 13, 285, 3954, 4775, 2190, 2571, 13, 534, 45162, 8811, 476, 22773, 275, 15, 187, 187, 47, 28147, 13, 3910, 2226, 875, 1980, 11967, 285, 5213, 11967, 28, 187, 187, 22817, 11967, 3959, 247, 1029, 4248, 273, 7031, 275, 2426, 273, 27, 187, 187, 783, 2020, 19420, 313, 13074, 6503, 2408, 10, 187, 187, 783, 7970, 2701, 187, 187, 9328, 778, 3959, 625, 5373, 285, 625, 9470, 7031, 313, 74, 15, 70, 15, 2923, 1557, 10, 187, 187, 18590, 7031, 187, 187, 8093, 12490, 13, 2969, 285, 3576, 34432, 7259, 187, 187, 12599, 11967, 2085, 253, 3058, 7031, 285, 513, 247, 1175, 2628, 387, 352, 15, 19988, 569, 671, 2226, 1561, 1980, 11967, 7293, 327, 253, 7031, 2098, 247, 1436, 33549, 323, 15, 187, 187, 3039, 352, 3249, 281, 34992, 13, 253, 34992, 4775, 17907, 313, 37, 10114, 10, 44143, 253, 5927, 6095, 323, 3739, 6503, 323, 34992, 8811, 15, 1876, 6503, 4413, 452, 281, 320, 399, 10114, 38147, 285, 253, 6095, 2486, 27, 187, 187, 34, 5927, 273, 329, 1703, 8970, 13, 933, 591, 807, 273, 7031, 187, 187, 46, 395, 2473, 45171, 414, 7031, 187, 187, 18608, 1096, 638, 14, 20137, 2515, 403, 6107, 187, 187, 2302, 2363, 2701, 672, 29018, 247, 3646, 15, 13314, 1037, 13, 42091, 812, 452, 13072, 5277, 7031, 846, 247, 2176, 2363, 15, 187, 187, 4967, 651, 368, 878, 4775, 16, 41225, 16541, 32, 187, 187, 19895, 16541, 3400, 247, 4618, 2491, 273, 5373, 281, 697, 29184, 13, 1110, 2486, 27, 187, 187, 31996, 486, 323, 40083, 313, 9453, 581, 556, 281, 3297, 387, 247, 4675, 10, 285, 1388, 14, 15325, 1971, 275, 247, 4675, 187, 187, 31996, 486, 323, 29964, 12941, 313, 9453, 368, 4143, 281, 247, 14235, 10, 390, 247, 4675, 187, 187, 46, 33040, 7031, 1108, 627, 403, 2067, 2308, 273, 45171, 414, 1557, 326, 476, 320, 2530, 285, 352, 457, 84, 598, 281, 253, 1436, 281, 5206, 534, 1511, 273, 7031, 19519, 731, 1682, 313, 35529, 627, 310, 247, 5927, 2408, 326, 556, 281, 320, 2530, 323, 34992, 2556, 281, 399, 10114, 10, 187, 187, 25727, 811, 26754, 476, 320, 6107, 187, 187, 5804, 1209, 1971, 476, 320, 2530, 187, 187, 31996, 323, 23066, 18740, 310, 2130, 187, 187, 1785, 17439, 422, 5869, 476, 320, 6107, 604, 3058, 187, 187, 1785, 16626, 12222, 476, 320, 6107, 187, 187, 43535, 17997, 16138, 3238, 187, 187, 688, 15325, 19830, 1971, 5092, 320, 5907, 187, 187, 18919, 989, 9749, 1108, 44871, 285, 45304, 547, 1557, 187, 187, 12018, 317, 2368, 285, 1234, 26628, 318, 3238, 187, 187, 26149, 800, 4918, 604, 3058, 187, 187, 2512, 403, 1142, 4278, 281, 4775, 16541, 285, 352, 457, 84, 1774, 281, 19148, 841, 4278, 285, 755, 40155, 273, 752, 368, 403, 11280, 715, 1078, 18000, 327, 752, 281, 22773, 275, 15, 187, 187, 4041, 588, 452, 281, 1239, 949, 253, 6010, 5373, 285, 253, 2426, 708, 2515, 273, 247, 3646, 275, 1340, 281, 4751, 2096, 697, 4278, 15, 733, 310, 4619, 281, 1089, 271, 6503, 23497, 326, 310, 4704, 281, 2085, 368, 342, 253, 19843, 368, 878, 13, 285, 436, 310, 835, 8939, 376, 16541, 4819, 23521, 3249, 275, 15, 844, 2085, 253, 19843, 326, 368, 8327, 275, 1340, 281, 1056, 253, 987, 3061, 285, 359, 452, 644, 2509, 352, 275, 253, 45162, 1580, 253, 11994, 84, 15, 187, 187, 10572, 8939, 376, 187, 187, 29764, 376, 16541, 4819, 23521, 16169, 310, 247, 2567, 11217, 285, 5368, 762, 253, 5323, 273, 253, 1986, 8365, 47229, 5877, 45162, 16541, 17907, 23497, 7981, 1180, 20825, 34, 34668, 14515, 1157, 1257, 35752, 314, 25032, 708, 24782, 323, 15, 187, 52, 7958, 5464, 285, 19528, 2112, 342, 16336, 7920, 313, 285, 411, 445, 273, 2282, 2387, 1160, 441, 1928, 9848, 285, 30459, 11712, 15, 187, 47638, 4328, 323, 247, 4143, 281, 12843, 12824, 3928, 15, 187, 187, 34, 25480, 7707, 187, 187, 35678, 11634, 275, 31596, 6169, 13, 436, 3722, 708, 12561, 310, 1561, 721, 3641, 313, 740, 10771, 10, 273, 1503, 15989, 2932, 38987, 4913, 13, 31596, 6169, 3228, 6696, 13, 285, 8139, 7673, 187, 187, 510, 9841, 30074, 456, 2316, 327, 253, 374, 2109, 5254, 369, 1270, 15, 733, 434, 747, 285, 4076, 15, 380, 3722, 369, 5882, 285, 9848, 15, 380, 8614, 12561, 369, 1270, 428, 2969, 533, 2217, 281, 6008, 15, 380, 760, 4468, 369, 253, 11008, 15, 2091, 253, 2316, 390, 22298, 11008, 27599, 13, 352, 27599, 11306, 534, 476, 320, 3735, 4518, 13, 1014, 3304, 253, 2316, 15, 187, 187, 53, 3385, 7707, 432, 13533, 187, 187, 16395, 456, 275, 253, 2798, 273, 31596, 6169, 13, 436, 42830, 14, 19771, 8614, 310, 1561, 374, 3641, 313, 20, 10771, 10, 273, 43767, 3767, 29410, 13, 380, 13958, 19670, 13, 285, 8139, 7673, 187, 187, 24757, 293, 21444, 187, 187, 35, 4415, 6169, 310, 6789, 1905, 1089, 253, 3962, 8614, 187, 187, 23631, 5605, 281, 4868, 247, 2968, 327, 4288, 13, 533, 4376, 310, 816, 581, 2803, 281, 1908, 672, 30170, 271, 42439, 788, 2420, 8614, 15, 12369, 368, 457, 250, 13975, 2021, 13, 16362, 247, 8059, 390, 3192, 247, 973, 14, 613, 9306, 18125, 275, 31596, 6169, 13, 1907, 271, 13103, 2793, 943, 320, 247, 642, 14, 21590, 254, 15, 187, 187, 24757, 22302, 588, 10584, 368, 598, 2, 4325, 1551, 1020, 15513, 2822, 634, 8630, 281, 326, 4335, 6308, 275, 253, 2846, 457, 84, 2798, 13, 359, 457, 306, 2218, 776, 2561, 281, 3324, 253, 1682, 4610, 281, 634, 48803, 15, 7225, 634, 31596, 6169, 8614, 342, 441, 1024, 285, 1265, 634, 1735, 15865, 15, 187, 187, 1394, 457, 250, 417, 253, 3388, 4288, 254, 1905, 285, 359, 871, 352, 187, 187, 1394, 457, 306, 2218, 634, 32110, 285, 871, 4555, 835, 368, 971, 281, 564, 15, 844, 457, 250, 1060, 281, 1361, 342, 690, 9405, 22302, 4288, 3471, 1441, 14, 37407, 12192, 327, 849, 281, 5321, 327, 634, 30170, 15, 187, 187, 3633, 1977, 323, 253, 8849, 187, 187, 24757, 1241, 275, 8750, 8238, 3798, 4179, 2169, 4142, 1309, 253, 2129, 13, 672, 952, 403, 15153, 323, 2136, 15, 12664, 1727, 476, 320, 247, 27871, 2, 733, 457, 84, 253, 643, 1039, 1475, 323, 18125, 13977, 13, 594, 604, 368, 457, 250, 2819, 323, 247, 11600, 8773, 13, 1908, 247, 4260, 14, 11151, 7408, 15, 187, 187, 19735, 4834, 690, 43610, 10582, 2316, 187, 187, 2042, 634, 5827, 403, 12112, 13, 1132, 1475, 342, 690, 1027, 4288, 12282, 1108, 247, 5333, 273, 247, 1643, 1897, 2057, 1039, 476, 1361, 368, 5321, 1943, 15, 367, 5395, 3798, 6923, 253, 29665, 1078, 285, 846, 4633, 23193, 13, 594, 359, 5583, 21406, 2590, 273, 731, 15, 2207, 1908, 13975, 1309, 253, 745, 14, 13263, 13, 672, 7911, 403, 3839, 2406, 15, 187, 187, 23092, 1475, 1943, 3394, 187, 187, 6723, 7911, 19143, 1029, 32, 1707, 1537, 320, 247, 5699, 8059, 390, 16365, 275, 3874, 15, 11680, 19507, 634, 12282, 604, 368, 476, 15, 4683, 2282, 13, 604, 326, 457, 84, 2139, 368, 457, 250, 1469, 13, 368, 457, 620, 452, 281, 18470, 253, 16950, 15, 844, 457, 620, 1335, 789, 281, 755, 368, 253, 1682, 4142, 562, 627, 15, 187, 187, 47, 836, 282, 689, 747, 27420, 187, 187, 4531, 9255, 673, 281, 2098, 752, 368, 971, 281, 923, 13, 9075, 285, 9413, 15, 13529, 29141, 247, 7408, 13, 1943, 390, 1355, 13, 751, 247, 1643, 747, 8450, 2, 9423, 2846, 11222, 390, 2170, 14248, 281, 1089, 562, 752, 457, 84, 747, 285, 752, 3394, 403, 9369, 1309, 634, 3297, 15, 4952, 1309, 247, 2021, 45591, 13, 368, 476, 843, 454, 281, 326, 25108, 14, 7483, 6773, 246, 15861, 1462, 390, 762, 14, 783, 14, 4614, 274, 3440, 5453, 15, 5402, 37827, 588, 320, 17847, 15, 2809, 249, 1916, 33655, 22364, 272, 1457, 33500, 434, 13927, 31633, 187, 187, 34, 25592, 18700, 723, 436, 2129, 23849, 253, 13910, 3727, 273, 253, 11386, 20590, 432, 33655, 1916, 33655, 13, 253, 1930, 2199, 273, 40720, 22234, 8359, 23237, 15, 187, 187, 1394, 476, 4089, 253, 4060, 3540, 745, 253, 1881, 14, 85, 5924, 5400, 2708, 13, 23633, 273, 25852, 2184, 255, 15, 681, 15, 380, 1563, 2315, 3727, 369, 671, 6808, 670, 253, 5400, 27, 187, 187, 3, 34, 10510, 8359, 23237, 434, 1416, 310, 954, 2223, 2330, 342, 253, 25427, 17712, 414, 13, 1907, 644, 253, 1421, 40720, 323, 690, 273, 616, 954, 41116, 16784, 1690, 9240, 8452, 32005, 43475, 13, 13869, 6061, 2799, 13, 8801, 414, 1680, 380, 32974, 285, 1023, 3743, 496, 380, 19662, 4683, 23264, 13, 275, 1635, 281, 15979, 23599, 13, 3192, 629, 275, 253, 43045, 13, 7663, 285, 3275, 273, 753, 5861, 285, 1199, 625, 15, 3032, 787, 34054, 13, 25760, 67, 4894, 14, 2050, 3197, 14088, 3740, 3133, 3587, 1398, 5483, 281, 6365, 455, 3737, 285, 690, 273, 253, 18353, 6912, 14564, 7635, 1225, 22271, 13, 2568, 45511, 323, 247, 625, 48593, 12178, 13, 48264, 14, 71, 382, 8446, 15, 187, 187, 3, 23021, 23237, 671, 4447 ]	Epstein-Barr virus (EBV) lytic phase are important predictive markers for nasopharyngeal carcinoma (NPC) risk. Several lifestyle factors, including smoking, have also been associated with NPC risk. We hypothesized that some specific lifestyle factors induce transformation of EBV from the latent to the lytic stage and contribute to NPC occurrence. We conducted a case-control study using data from male case patients (n = 1316) and control subjects (n = 1571) living in Guangdong Province, an area in China at high risk for NPC, to study potential NPC risk factors and EBV inducers. Two independent healthy male populations from a second high-risk area (n = 1657) and a low-risk area (n = 1961) were also included in the analysis of potential EBV inducers using logistic regression models. In vitro assays were performed to investigate the effect of cigarette smoke extract on EBV activation in two EBV-positive cell lines. All statistical tests were two-sided. Smoking was associated with an increased risk of NPC among the Guangdong participants with 20-40 and 40 or more pack-years vs never smokers (OR = 1.52, 95% CI = 1.22 to 1.88 and OR = 1.76, 95% CI = 1.34 to 2.32, respectively; P (trend) <.001). Smoking was the only factor linked to EBV seropositivity among the expanded control group and the independent low-risk population. In vitro experiments showed that cigarette smoke extract promoted EBV replication, induced the expression of the immediate-early transcriptional activators Zta and Rta, and increased transcriptional expression levels of BFRF3 and gp350 in the lytic phase. Smoking is not only associated with NPC risk in individuals from China but is also associated with EBV seropositivity in healthy males and is involved in EBV activation.Health Insurance What is Health/Medical Insurance? The cost involved in health care today is extremely high and continuously increasing, which is where health/medical insurance becomes important. Medical emergencies can happen at any moment, and besides the impact on one’s health, these emergencies can have a major impact on the financial standings of an individual or a family. Medical insurance covers the financial loss during emergencies (or even non emergencies) and when a person gets sick. Health/Medical insurance is insurance against the risk of incurring medical expenses whether it is individuals or corporations that are paying for the medical insurance expenses. It is the coverage that provides the payments of benefits as a result of sickness or injury. How does Health/Medical Insurance work? Different types of insurance providers exist. There are local (UAE) providers and international providers such as BUPA, AETNA, and Now Health among others, which UAE residents can enroll in. Naturally, differences exist between local providers and international providers; International providers offer a high degree of coverage in terms of: the sum insured (total insurance amount) the annual limit they may offer more benefits and more extensive coverage (i.e. cancer care) Global coverage Streamlined, simple and effective reimbursement procedures Local providers provide the needed coverage and do a good job at it. Variations also exist within local providers depending on the coverage plan a person opted for. When it comes to Dubai, the Dubai Health Authority (DHA) mandates the minimum requirements for medical insurance for Dubai residents. All insurance companies have to be DHA compliant and the requirements include: A minimum of AED150,000 per year of coverage Mandatory maternity coverage Declared pre-existing conditions are covered No age limit when issuing a policy. Historically, insurers could have declined providing coverage after a certain age. Why would you need Health/Medical Insurance? Health Insurance provides a wide range of benefits to its subscribers, those include: Coverage for inpatient (when one has to stay at a hospital) and day-patient treatment in a hospital Coverage for outpatient visits (when you visit to a clinic) or a hospital Maternity coverage – there are several levels of maternity care that can be provided and it’s up to the person to choose which type of coverage suits them best (however there is a minimum amount that has to be provided for Dubai according to DHA) Organ transplants can be covered Cancer treatment can be provided Cover for newborn babies is available Reconstructive surgery can be covered if needed Rehabilitation expenses can be covered Emergency dental services Inpatient psychiatric treatmentcan be offered Terminal illness – palliative and hospice care Evacuation and repatriation services Alternative therapy if needed There are many details to Health Insurance and it’s important to clarify these details and get specifics of what you are buying into before deciding on what to enroll in. One will have to read through the summary benefits and the terms & conditions of a policy in order to fully understand its details. It is critical to find an insurance broker that is ready to provide you with the clarity you need, and this is where Petra Insurance Brokers comes in. We provide the clarity that you desire in order to make the right decision and we have been doing it in the UAE since the 1960s. About Petra Petra Insurance Brokers LLC is a company incorporated and existing under the laws of the United Arab Emirates holding UAE Insurance Authority broker license number 147A delightful Inn,beautifully furnished & cared for. Suzette and Roger along with Sabrine ( and Wren of course ) made us feel comfortable and pampered. Perfect location for a visit to Prince Edward County. A Traveller Situated in Belleville, this bed & breakfast is within 6 mi (10 km) of Zwick Centennial Park, Belleville City Hall, and …More The newly renovated room on the 2nd floor was great. It's new and clean. The bed was firm and comfortable. The hotel breakfast was great - simple but enough to eat. The only concern was the doors. When the room or stair doors closes, it closes heavily which can be heard clearly, even inside the room. Traveller from Toronto Located in the heart of Belleville, this eco-friendly hotel is within 2 mi (3 km) of Yardmen Arena, The Empire Theatre, and …More Hotel Brand Belleville is calling — find the perfect hotel Everyone wants to score a deal on travel, but price is just one factor to consider when booking an unforgettable hotel. Whether you’re visiting family, attending a conference or taking a well-earned vacation in Belleville, having an awesome experience should be a no-brainer. Hotwire will hook you up! From restful nights near your flight to that prime spot in the city’s heart, we’ve done our research to bring the best options to your fingertips. Book your Belleville hotel with us now and start your next adventure. You’re not the average traveler — and we know it You’ve done your homework and know exactly where you want to go. We’re here to help with some Hotwire travel geek-approved tips on how to save on your booking. Get away for the weekend Hotels in bigger cities usually charge higher rates during the week, when people are traveling for business. Weekends can be a bargain! It’s the other way around for vacation spots, so if you’re looking for a beach escape, consider a mid-week trip. Give yourself some wiggle room If your plans are flexible, play around with some different travel dates – a shift of a few days either way can help you save big. Prices usually jump the weekends before and after popular holidays, so we recommend steering clear of them. Or consider visiting during the off-season, when prices are generally lower. Plan around big events Are prices surprisingly high? There might be a huge conference or festival in town. Consider shifting your dates if you can. Of course, if that’s why you’re going, you’ll have to bite the bullet. We’ll still work to get you the best rates out there. Noodle over new adventures Set aside time to plan what you want to see, taste and discover. Nothing completes a trip, big or small, like a few new experiences! Check city apps or area websites to find out what’s new and what events are happening during your stay. Even during a family reunion, you can detour to that locals-only fish taco stand or under-the-radar music club. Your cousins will be impressed.Shin To Shin Streaming New Album's Title Track A389 Recordings this week confirms the pending release of the debut LP from Shin To Shin, the side project of guitarist Aaron Melnick. You can hear the title track off the self-titled album below, courtesy of Lambgoat.com. The following press release was also issued about the album: "Aaron Melnick's name is most often associated with the mighty Integrity, having been the lead guitarist for some of their most seminal releases including Those Who Fear Tomorrow, Systems Overload, Humanity Is The Devil and Seasons In The Size Of Days, in addition to contributing vocals, taking part in the arranging, recording and production of said records and much more. His blazing, divebomb-infused solo style seems directly descendant to Metallica and some of the earliest Bay Area thrash heroes, yet fueled for a more deplorable, clenched-fist audience. "Melnick also formed
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1893, 253, 346, 1171, 3, 2986, 18922, 326, 253, 346, 2522, 14, 251, 14, 783, 14, 3956, 14, 1171, 14, 12550, 14, 11425, 398, 14, 936, 14, 783, 14, 10981, 429, 14 ]	right leg. Stretch both legs out into Staff, and bounce your knees on the floor a few times. Repeat the pose for the same length of time with the left leg. Technically, when the right leg is crossed over the left, it's called Right Half-Lotus Pose ( _dakshina ardha padmasana_ ), and when the left is over the right, it's Left Half-Lotus Pose ( _vama ardha padmasana_ ). __Practice 2: Full Lotus__ From Half-Lotus, lean back slightly, pick the right leg up off the floor, and lift the left leg in front of the right. To do this, hold the underside of the left shin in your hands. Carefully slide the left leg over the right, snugging the edge of the left foot deep into the right groin. Again, swivel into position from the hip joint, press the left heel against the lower right belly, and arrange the sole perpendicular to the floor. Draw the knees as close together as possible. Use the edges of the feet to press the groins toward the floor, and lift through the top of the sternum. Stay for 1 to 3 minutes, then release the legs into Staff and bounce the knees a few times. Repeat with the legs reversed for the same length of time. __Traditional Benefit__ All three sourcebooks claim that Lotus wards off disease. The _Hatha-Yoga-Pradipika_ and _Shiva-Samhita_ suggest that through working with the breath in Lotus, the practitioner can achieve liberation. LITTLE LAMP: YOGA If I read Gheranda correctly, Yoga Pose is a kind of "loose" Lotus. In his directions for the latter, he says to place each foot on top of the opposite thigh ( _uru_ ), while for Yoga, he says to place each foot on the opposite knee ( _janu_ ). This pose is optional. __Practice__ Cross each foot over to the opposite thigh, gaze at the tip of the nose, and lay the backs of the hands on the floor outside the hips. __Traditional Benefit__ Gheranda makes reference to this pose bringing "success" in yoga. R OOSTER POSE (KUKKUTASANA) __KUKKUTA__ • rooster Full Rooster involves slipping the hands and arms between the Lotus-shaped thighs and calves, pressing the hands to the floor, and lifting the torso and legs off the floor. This is beyond the ability of most students, so here we'll perform a "free-arm" variation of Rooster that today is called Scale Pose ( _tolasana,_ literally "poising one's self, weighing"; see _Light on Yoga_ #48). There are two practices, the first for Half-Lotus and the second for full Lotus. If you have trouble lifting off the floor in either version, press each hand against either the side or the face of a yoga block to create more space between you and the floor. __Practice 1: Scale in Half-Lotus__ In Half-Lotus, you may not be able to quite lift the lower leg off the floor. If not, bind the lower leg to the upper one with a strap. Make a loop, pass it under the bottom foot and over the top leg's inner groin, and snug (but don't tighten) it. Press your hands to the floor beside your hips; lean your torso slightly forward; and firming your lower belly, lift your legs off the floor with an exhalation. Hold for 15 to 30 seconds, then lower lightly back down to the floor. Fig. 14. Rooster Pose ( _kukkutasana_ ). __Practice 2: Scale in Full Lotus__ The instructions for Scale in Full Lotus are the same as those for Half-Lotus. _Traditional Benefit_ None listed. F ISH POSE (MATSYASANA) __MATSYA__ • fish Traditionally, Fish Pose might be called Reclining Lotus, because it's performed as a flat-out supine position with the legs in Lotus (see _Light on Yoga_ #114). In modern yoga, it's sometimes performed as a backbend with the head and legs on the floor, the arms crossed overhead, and the torso arched off the floor ( _Light on Yoga_ #113). Here, we'll work with the traditional flat-out version. If you find it difficult to recline your torso fully on the floor, then you have two choices: you can lie back on some kind of support, such as a bolster or thickly folded blanket, or before you lie back, you can slip your legs out of Half- or full Lotus and simply cross them in Easy Pose ( _sukhasana_ ). LITTLE LAMP: WHY DOES FISH POSE LOOK LIKE A FISH? How or why does this pose look like a fish? This question bothered me for a long time, as I assumed that every pose named after a living creature should look at least vaguely like its namesake. Then I ran across this explanation in _Popular Yoga Asanas_ by Swami Kuvalayananda: "The pose is called Matsyasana because in swimming a person can float on water, like the fish, for a considerable time, if he steadily lies there in this posture." It sounds somewhat plausible, though I'm not sure the pose is really needed if all you want to do is float. Fig. 15. Fish Pose ( _matsyasana_ ). This brings up a question: is floating part of traditional Hatha Yoga? It turns out the answer is yes, at least it was 650 years ago in the time of Svatmarama. His instructions are to swallow a large amount of air into your belly and then you can float ( _plu_ ) happily like a lotus leaf, even in deep ( _agadha_ ) water. This is a _pranayama,_ believe it or not, called Floating ( _plavini_ ). I suppose this practice might have been akin to our current floating in an isolation tank. By the way, can you swallow air? The answer, again, is yes. __Practice__ In Lotus, exhale, lie back, and cross your forearms overhead, holding each elbow with the opposite hand. Stay in position for up to 1 minute. Bring the torso and head up with an inhalation, leading with your chest if possible and letting your head trail. __Traditional Benefit__ Fish Pose wards off disease. LITTLE LAMP: UTTANA KURMASANA Raised Tortoise Pose is traditionally performed with the arms inserted through the Lotus legs, just like Rooster. But we'll do it with the arms outside the Lotus legs. This pose is optional. __Practice__ From Fish, draw the legs in to the torso and wrap the arms around the outer thighs. Stay in this position for one to two minutes. _Traditional Benefit_ None listed. SECTION 5: FORWARD BENDS There are four poses in this section: one of them an asana-like mudra ( _maha mudra_ ); one a straight-ahead sitting forward bend; one a pose that changed its shape entirely between the time of Svatmarama and that of Gheranda; and the fourth, which isn't a forward bend but the only real twist in _Gheranda-Samhita._ G REAT SEAL (MAHA MUDRA) We'll run into Great Seal again as itself in the next chapter. Here we'll use the position as a jumping-off place for a sitting forward bend we call Head-to-Knee Pose ( _janu shirshasana;_ see _Light on Yoga_ #59). I should note that there's been some controversy about this interpretation of the Sanskrit name in certain quarters of the yoga community—not about _janu_, which everyone agrees means "knee" (and cognate with Latin _genu,_ from which we get "genuflect"), nor over _shirsha,_ which undeniably means "head." The disagreement swirls around the preposition "to," which some believe should be "of," a seemingly slight change with significant implications. Fig. 16. Great Seal ( _maha mudra_ ). According to the latter camp, the expression "head- _to_ -knee" isn't entirely wrong (after all, in the final position of the pose, the practitioner's head is on the straight-leg knee), it just encourages a mistaken idea about the goal of the exercise, especially in beginning students. Hearing "head-to-knee," beginners often take this as a divine command and try, despite their physical limitations such as tight hamstrings, to do just that, resulting in all sorts of strange-looking and potentially injurious forward bends. So the "of" camp maintains that the "head-on-the-top-of-your-shoulders-to-the-straight-
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670, 1880, 697, 625, 5899, 13, 10827, 7431, 812, 8722, 281, 755, 10870, 7031, 275, 247, 2164, 16, 24, 3778, 14, 17477, 3420, 44703, 15, 1292, 17966, 310, 247, 1018, 43307, 13216, 665, 476, 3923, 27815, 13, 347, 359, 457, 306, 4102, 2326, 1905, 534, 812, 5276, 247, 13741, 46053, 1584, 15, 187, 187, 22, 10, 743, 512, 14, 17217, 13571, 651, 1056, 2892, 27, 15594, 13, 253, 4884, 281, 9662, 434, 1211, 14464, 23726, 556, 644, 8489, 2873, 264, 15, 1292, 253, 2934, 273, 1469, 432, 642, 2255, 37627 ]	-feira quatro torres da operadora Vodafone foram no Reino Unido foram incendiadas, e três outras já haviam sido incendiadas anteriormente. A operadora também afirma que seus técnicos e engenheiros estão sendo ameaçados por cidadãos que acreditam que as torres, se forem colocadas em operação, “vão matar todo mundo”. "Sinto informar que vândalos realizaram uma série de ataques criminosos a torres de telefonia celular durante este período de crise nacional", diz Nick Jeffery, CEO da Vodafone UK. “Agora é uma questão de segurança nacional. As autoridades policiais e de combate ao terrorismo estão investigando. ” As principais operadoras de telefonia do Reino Unido (Three, EE, Vodafone e O2) emitiram um comunicado conjunto negando a teoria da conspiração e pedindo ajuda dos consumidores para parar com os ataques. Elas lembram que neste momento, com milhões de pessoas trabalhando remotamente e em isolamento social, suas redes são cruciais para a educação, produtividade, comunicação e entretenimento da população. “É difícil acreditar que algumas pessoas querem prejudicar as redes que estão fornecendo conectividade essencial para os serviços de emergência, o sistema nacional de saúde e o resto do país durante este período de quarentena”, disse Jeffery. YouTube intervém O YouTube decidiu intervir para auxiliar na contenção dos rumores. Vídeos com teorias de conspiração relacionadas à segurança das redes 5G, mas que não mencionem o coronavírus, serão “suprimidos”, através da suspensão de anúncios e de sua eliminação nos resultados de busca da plataforma. Já vídeos que afirmam haver uma ligação entre o vírus e as redes 5G serão removidos da plataforma, já que violam a política da empresa que não permite a divulgação de métodos não comprovados pela comunidade médica para prevenir ou curar a doença. Segundo o YouTube, desde fevereiro milhares de vídeos com informações falsas ou enganosas sobre o coronavírus foram removidos. Entretanto, trata-se de um jogo de gato e rato já que, frequentemente, momentos depois de um vídeo ser removido múltiplas cópias novas aparecem na rede. Mats Granryd, diretor geral da GSMA, organização que representa o interesse de empresas da indústria de telefonia em todo o mundo, disse: “A indústria de telecomunicações está trabalhando dia e noite para manter serviços vitais de saúde, educação e emergência on-line, além de negócios funcionando e amigos e famílias conectados. É deplorável que a infra-estrutura crítica de comunicações esteja sendo atacada com base em tamanhas mentiras. Pedimos a todos que confiem nas autoridades de saúde e tenham certeza de que a tecnologia de comunicação é segura. Não há ligação entre 5G e Covid-19”. Confira em tempo real a COVID-19 no Brasil:Political insiders used to scoff at the idea that Hillary Clinton would choose Elizabeth Warren for her running mate. But multiple reports have found that she's one of the contenders on a shortlist that will soon be vetted by the Clinton team, alongside Virginia Sen. Tim Kaine, Housing and Urban Development Secretary Julian Castro, and potentially others. And on Monday, Clinton and Warren will campaign together at an event in Cincinnati, in what could well be an audition for veep. Many Democratic elites seem to be thrilled about the idea of a Clinton-Warren ticket. In April, the Huffington Post’s Ryan Grim quoted a "member of Clinton’s inner circle" saying, "Real folks are pushing Warren. I’m into it." Allies of Senate Democratic Leader Harry Reid have been very clear to the press that he thinks Warren would be the best choice. But does this pairing make sense — for Clinton, for Warren, for progressives, and for the Democratic Party as a whole? The answer to this question is complicated by the utter strangeness of the vice presidency. The office lacks practically any formal powers, which means that a vice president’s influence depends largely on the president’s whims. Consequently, there are good arguments that Warren can be more powerful if she's not vice president. Some recent vice presidents — most famously Dick Cheney, but also Joe Biden — have had a great deal of influence, though. Plus, there’s the small matter that a twist of fate could make whomever gets the job the most powerful person in the world. And then there’s the fact that many presidential nominees seem to ignore all this in favor of choosing a running mate solely for short-term electoral reasons. So, keeping this complex set of considerations in mind, here are the best arguments Democrats have been making for and against choosing Warren as Clinton’s No. 2. The case for Vice President Warren 1) An important progressive voice would be on the ticket and in a Clinton White House: Symbolically and substantively, a Warren nomination would be a major acknowledgement of progressives’ importance in the modern Democratic Party. She'd be the most liberal vice presidential nominee in decades; her selection could help convince progressives that this Clinton administration won't pivot to the center and leave progressives behind. (After all, Warren would be around to give them hell for it if they do.) Furthermore, Warren has already figured out how to exercise a surprising amount of influence even as a first-term senator — she’s managed to torpedo several high-profile Obama administration appointments. The vice presidential position would give her far more prominence and an even bigger media megaphone. And depending on what President Clinton allowed her to do, Warren could have a great deal of influence on many crucial under-the-radar appointments and administrative matters like Dick Cheney once did. An unleashed Vice President Warren could champion progressive causes and combat corporate lobbyists and moneyed interests throughout the labyrinthine rulemaking process and federal government. 2) She’d unite Democrats, excite Sanders supporters, and turn out the left: With the Bernie Sanders campaign apparently winding down, the question of whether his supporters will rally around Clinton is on many Democrats’ minds. Most party elites currently assume that they will, since Sanders himself is highly likely to endorse her and since stopping Trump seems so important. But much of Sanders’s support was drawn from voters who identified as independents — many of them feel disenchanted by a Democratic Party they view as calcified, corporate, and corrupt. It’s possible that many of them could stay home unless the party makes a major effort to change its image — for instance, by choosing a populist anti–Wall Street crusader like Warren as Clinton's running mate. (A recent poll shows Warren is quite popular among Sanders voters who are currently saying they’ll refuse to support Clinton in the general election.) More broadly, Warren could excite the Democratic base and galvanize turnout on the left — which could make a crucial difference in an increasingly polarized electorate where independent voters are less important. 3) She's an excellent attack dog who gets under Trump's skin: A traditional role of the vice presidential pick is that of the "attack dog" — someone who will aggressively go after the other party’s nominee while theoretically letting his or her own nominee remain at least somewhat above the fray. And if Warren has proved one thing in the past few months, it’s that she’d be a fantastic attack dog against Donald Trump. On Twitter, she’s shown herself to be willing to provoke Trump with a slash-and-burn style. And in a speech earlier this month she tore Trump to shreds, calling him a "thin-skinned, racist bully." Furthermore, Warren really seems to get in Trump’s head, and frequently provokes over-the-top reactions from him. A vice presidential nominee who could drive Trump up the wall and force him to wound himself in response would be great for the Clinton campaign. Watch: Elizabeth Warren goes on attack against Donald Trump 4) She’d get tons of media attention: Relatedly, the Clinton campaign has reportedly been seriously concerned about whether its more traditional, reserved candidate could manage to get comparable coverage in a 24/7 Trump-driven media circus. But Warren is a charismatic personality who can command headlines, as we’ve recently seen — which could prove a potent antidote. 5) An all-woman ticket would make history: Sure, the reaction to Clinton's own historic nomination has been somewhat muted. But the idea of going from no women presidents
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380, 952, 497, 1925, 2366, 281, 42009, 387, 14383, 9896, 15, 187, 22, 1244, 253, 6778, 382, 1100, 13037, 2366, 281, 3819, 1411, 5143, 28, 10488, 8014, 1018, 74, 1502, 285, 2800, 8014, 8815, 3767, 13, 285, 952, 751 ]	Do you see him whom YEHOWAH has chosen, that there is none like him among all the people?” So all the people shouted and said, “Save the king!” 25 Then Samuel told the people the ordinances of the kingdom, and wrote them in the book and placed it before YEHOWAH. And Samuel sent all the people away, each one to his house. 26 Saul also went to his house at Gibeah; and there went with him a band of men whose hearts Elohim had touched, 27 but the children of Belial said, “How can this one save us?” And they despised him and did not bring him any present. But he kept silent. CHAPTER 11 Then Nahash the Ammonite came up and encamped against Jabesh-gilead; and all the men of Jabesh said to Nahash, “Make a covenant with us and we will serve you.” 2 But Nahash the Ammonite answered them, “I will make it with you on this thing: that I will thrust out all your right eyes, thus I will make it a reproach on all Israel.” 3 The elders of Jabesh said to him, “Leave us alone for seven days, that we may send messengers into all the territory of Israel, and if there is none to save us, we will come out to you.” 4 Then the messengers came to Gibeah of Saul and spoke these words in the ears of the people, and all the people lifted up their voices and wept. 5 And behold, Saul came after the herd from the field, and he said, “What is with the people that they weep?” So they told him the words of the men of Jabesh. 6 Then The Spirit of Elohim came upon Saul mightily when he heard these words, and his anger was kindled greatly. 7 And he took a pair of oxen and cut them in pieces, and sent them throughout the territory of Israel by the hand of messengers, saying, “Whoever comes not forth after Saul and after Samuel, so shall it be done to his oxen.” Then the fear of YEHOWAH fell upon the people, and they came out as one person. 8 And he numbered them in Bezek; and the children of Israel were three hundred thousand, and the men of Yehudah thirty thousand. 9 And they said to the messengers who had come, “Thus you shall say to the men of Jabesh-gilead, ‘Tomorrow, by the time the sun is hot, you will have deliverance.'” So the messengers went and told the men of Jabesh; and they were glad. 10 Then the men of Jabesh said, “Tomorrow we will come out to you, and you may do to us whatever seems good in your sight.” 11 And it came to pass the next morning, that Saul put the people in three companies; and they came into the midst of the encampment, at the morning watch, and struck the Ammonites until the heat of the day. And it was, that those who remained were scattered, so that two of them were not left together. 12 Then the people said to Samuel, “Who said, ‘Shall Saul reign over us?’ Bring those men, that we may put them to death.” 13 But Saul said, “There shall not a man be put to death this day, for today YEHOWAH has brought forth salvation in Israel.” 14 Then said Samuel to the people, “Come and let us go to Gilgal, and renew the kingdom there.” 15 And all the people went to Gilgal, and there they made Saul king before YEHOWAH in Gilgal. There they also sacrificed sacrifices of peace offerings before YEHOWAH; and there Saul and all the men of Israel rejoiced greatly. CHAPTER 12 And Samuel said to all Israel, “Behold, I have heard your voice in all that you said to me, and I have appointed a king over you. 2 And now, behold, the king walks before you, but I am old and gray-headed, and behold my sons are with you. And I have walked before you from my childhood even to this day. 3 Here am I; bear witness against me before YEHOWAH and before His anointed. Whose ox have I taken, or whose ass have I taken, or whom have I defrauded? Whom have I oppressed, or from whose hand have I taken a bribe to blind my eyes with it? I will restore it to you.” 4 And they said, “You have not defrauded us or oppressed us or taken anything from any man’s hand.” 5 He said to them, “YEHOWAH is witness against you, and His anointed is witness this day that you have found nothing in my hand.” And they said, “He is witness.” 6 Then Samuel said to the people, “It is YEHOWAH who appointed Moses and Aaron and who brought your fathers up out of the land of Egypt. 7 And now stand still, that I may plead with you before YEHOWAH, of all the righteous acts of YEHOWAH that He did for you and your fathers. 8 When Jacob went into Egypt and your fathers cried out to YEHOWAH, then YEHOWAH sent Moses and Aaron, who brought your fathers out of Egypt and settled them in this place. 9 But they forgot YEHOWAH their Elohim, so He sold them into the hand of Sisera, captain of the army of Hazor, and into the hand of the Philistines and into the hand of the king of Moab, and they fought against them. 10 And they cried out to YEHOWAH and said, ‘We have sinned, because we have forsaken YEHOWAH and have served Baalim and the Ashtaroth; but now deliver us from the hands of our enemies, and we will serve You.’ 11 Then YEHOWAH sent Jerubbaal and Bedan and Jephthah and Samuel, and delivered you out of the hands of your enemies round about, so that you dwelt in security. 12 And when you saw that Nahash the king of the sons of Ammon came against you, you said to me, ‘No, but a king shall reign over us,’ when YEHOWAH your Elohim was your king. 13 And now behold, here is the king whom you have chosen, whom you have asked for, and behold, YEHOWAH has set a king over you. 14 If you will fear YEHOWAH and serve Him, and hear His voice and not rebel against the commandment of YEHOWAH, then both you and also the king who reigns over you will continue following YEHOWAH your Elohim. 15 But if you will not hear the voice of YEHOWAH, and rebel against the commandment of YEHOWAH, then the hand of YEHOWAH will be against you, as it was against your fathers. 16 Now therefore, take your stand and see the great thing that YEHOWAH will do before your eyes. 17 Is it not wheat harvest today? I will call to YEHOWAH, that He sends thunder and rain. Then you will know and see that your wickedness is great, which you have done in the sight of YEHOWAH by asking for yourselves a king.” 18 And Samuel called unto YEHOWAH, and YEHOWAH sent thunder and rain that day; and all the people greatly feared YEHOWAH and Samuel. 19 And all the people said to Samuel, “Pray to YEHOWAH your Elohim, for your servants, that we die not, for we have added to all our sins this evil by asking for ourselves a king.” 20 And Samuel said to the people, “Fear not. You have done all this evil, yet do not turn aside from following YEHOWAH, but serve YEHOWAH with all your heart; 21 and turn you not aside, to go after vain things that cannot profit or deliver, because they are vain. 22 For YEHOWAH will not forsake His people for His great name’s sake, because YEHOWAH has been pleased to make you His people. 23 Moreover, as for me, far be it from me that I should sin against YEHOWAH by ceasing to pray for you; but I will teach you in the good and right way. 24 Only fear YEHOWAH and serve Him in truth with all your heart; for consider what great things He has done for you. 25 But if you still do wickedly, you will perish, both you and your king.” CHAPTER 13 Saul was thirty years old when he began to reign, and in the second year of his reign, 2 Saul chose him three thousand men of Israel, of which two thousand were with Saul in Mikmas and in the hill country of Bethel, while one thousand were with Yehnathan at Gibeah of Benyahmin. But he sent away the rest of the people, each to their tent. 3 And Yehnathan smote the garrison of the Philistines that was in Geba, and the Philistines heard. Then Saul blew the trumpet throughout the land, saying, “Let the Hebrews hear.” 4 All Israel heard say, that Saul had smitten the garrison of the Philistines, and also that Israel had become odious to the Philistines. The people were called together to Saul at Gilgal. 5 And the Philistines gathered together to fight against Israel; thirty thousand chariots and six thousand horsemen, and people like
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At one point, Goldberg asked Kanye where he lives. "Earth," responded the rapper. Look for more of the deposition to make its way to the web soon. In the meantime, check out this throwback of Lil Wayne's still-hilarious 2012 deposition here.This is a volunteer-run guide that will help you set up a tablet for an elder isolated by COVID. No need to teach the senior how to use any technology. This guide will show you how to configure a tablet to automatically pick up when you initiate a video-call over Skype or Facetime. No WiFi required. This guide will help you buy a tablet from your wireless carrier that connects to the internet over the cellular network. When you've finished preparing the tablet, you can mail it to the elder, and all they have to do is turn it on and plug in the charger. If you have any trouble, you can reach out to our volunteer tech support for help.Scale model «The Gaza Strip is a territory of about 360 square kilometres, running up the Mediterranean coast towards Tel Aviv, bordered to the south by Egypt. It's a strip of land no more than 14km across at its widest point, six at its narrowest, and is said to be the most densely populated piece of earth in the world. It is home to more than a million Palestinians.» #ifndef PRINCIPIA_PHYSICS_BODY_HPP_ #define PRINCIPIA_PHYSICS_BODY_HPP_ #include "base/macros.hpp" #include "base/not_constructible.hpp" #include "base/not_null.hpp" #include "serialization/physics.pb.h" namespace principia { namespace physics { namespace internal_body { using base::not_constructible; using base::not_null; class Body { public: virtual ~Body() = default; // Returns true iff this body is massless. virtual bool is_massless() const = 0; // Returns true iff this body is oblate (which implies massive). virtual bool is_oblate() const = 0; // Returns true iff this body is compatible with the given frame (either // because it is spherical or because its axis is expressed in the same // frame). template<typename Frame> bool is_compatible_with() const; virtual void WriteToMessage(not_null<serialization::Body> message) const = 0; // Dispatches to one of the subclasses depending on the contents of the // message. static not_null<std::unique_ptr<Body>> ReadFromMessage( serialization::Body const& message); protected: Body() = default; private: // A helper struct which is here just so that we can specialize it on // \|is_inertial\|. This is necessary because we cannot dynamic cast to // OblateBody<Frame> if \|Frame\| is not inertial. template<typename Frame, bool is_inertial> struct CompatibilityHelper : not_constructible { static bool is_compatible_with(not_null<Body const> body); }; }; } // namespace internal_body using internal_body::Body; } // namespace physics } // namespace principia #include "physics/body_body.hpp" #endif // PRINCIPIA_PHYSICS_BODY_HPP_ Kraken’s Honor starts off in the midst of a shipwreck in the middleof a rocky shoal with dry land a mere breadth away. The two survivors are stuck on the prowl of the great ship the Ice Queen as the freezing ocean spray and waves disintegrates the ship around them. Their fate seems sealed, to die smashed against the rocks or in the belly of the Kraken waiting in the shallows. This fateful moment leaves Prince Faeryk with the certainty that he must return to his home of Westever and right the wrongful murder of his father at the hands of his brother, Faeryk’s Uncle. To accomplish this all he can relay on is his bard and friend Halvak, his father’s sword Wavetamer and the Honor of a Kraken. I’ve never had the pleasure to read a story by S. A. Bolich before and I must say I have been missing out. Bolich spins a mesmerizing tale of ancient wrongs and the binds that sins of our forefathers put on us. In this remarkably detailed short story you can’t help but be ensnared by the web of history and the depth of characters that are spun. Truly an excellent story made even more enjoyable by the fact that it is free to read online to everyone over at Beneath Ceaseless Skies.Surgically treatable growth retardation due to non-neoplastic pituitary-hypothalamic dysfunction. Out of 90 children, examined because of growth failure, 15 have been treated surgically. The diagnoses were intrasellar arachnoid diverticulum or empty sella (5 cases), enlarged chiasmatic cisterns (5 cases), chronic 'occult' hydrocephalus (5 cases). Surgery was followed by an immediate increase in growth rate in almost all the cases, even if the result was persistent only in some subjects. In percentage, better results were obtained in patients with enlarged chiasmatic cisterns and chronic occult hydrocephalus than in patients with arachnoid diverticulum or empty sella. The evaluation of prolactin serum levels was demonstrated to be useful both in preoperative diagnosis and postoperative control./****************************************************************************** * * Copyright 2016 Paphus Solutions Inc. * * Licensed under the Eclipse Public License, Version 1.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.eclipse.org/legal/epl-v10.html * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * ****************************************************************************/ package org.botlibre.sense.twilio; import java.io.StringWriter; import java.util.HashMap; import java.util.Map; import java.util.logging.Level; import org.botlibre.api.knowledge.Network; import org.botlibre.api.knowledge.Vertex; import org.botlibre.knowledge.Primitive; import org.botlibre.self.SelfCompiler; import org.botlibre.sense.BasicSense; import org.botlibre.sense.ResponseListener; import org.botlibre.thought.language.Language; import org.botlibre.tool.Date; import org.botlibre.util.Utils; import net.sf.json.JSONObject; import net.sf.json.JSONSerializer; / * Receive and respond to incoming email. * Can use any pop mail server, such as gmail. / public class Twilio extends BasicSense { public static int MAX_WAIT = 60 1000; // 1 minute protected String sid = ""; protected String secret = ""; protected String phone = ""; protected boolean initProperties; public Twilio() { } /** * Start sensing. / @Override public void awake() { } /* * Load settings. */ public void initProperties() { if (this.initProperties) { return; } synchronized (this) { if (this.initProperties) { return; } getBot().memory().loadProperties("Twilio"); String property = this.bot.memory().getProperty("Twilio.sid"); if (property!= null) { this.sid = property; } property = this.bot.memory().getProperty("Twilio.secret"); if ((property!= null) && (this.sid!= null)) { this.secret = Utils.decrypt(Utils.KEY, property); } property = this.bot.memory().getProperty("Twilio.phone"); if (property!= null) { this.phone = property; } this.initProperties = true; } } public void saveProperties() { Network memory = getBot().memory().newMemory(); memory.saveProperty("Twilio.sid", this.sid, false); memory.saveProperty("Twilio.secret", Utils.encrypt(Utils.KEY, this.secret), false); memory.saveProperty("Twilio.
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4590, 481, 329, 1599, 3064, 875, 10668, 273, 428, 17, 15, 11325, 313, 84, 15, 69, 15, 426, 470, 15, 18348, 10, 285, 378, 1373, 285, 21913, 1342, 5325, 6, 12285, 953, 273, 14297, 4503 ]	the value of chest X-ray in detecting left ventricular (LV) size and function is still controversial, and it has been suggested that less than half of the patients with LV systolic dysfunction show a cardiothoracic ratio \>55%.\[[@ref6][@ref7]\] Although comparison with other techniques has shown only a weak correlation between cardiothoracic ratio and radionuclide, echocardiographic, or magnetic resonance imaging (MRI)-derived volumes and ejection fraction (EF),\[[@ref8][@ref9]\] heart size on the chest X-ray is still of considerable prognostic value in the patients with low LV ejection fraction (LVEF).\[[@ref10]--[@ref12]\] Moreover, the measurement of the transverse chest dimensions could represent a source of error in the evaluation of the cardiothoracic ratio, which is the parameter considered for the assessment of heart size in most of the studies published so far. An index derived from cardiac silhouette, which does not take into account measures of the chest, could therefore provide more reliable parameters for definition of LV dimension and function. Cardiac MRI -- due to its good accuracy and superior reproducibility -- is now considered as the Gold Standard for in vivo quantification of left and right ventricular volumes and EF.\[[@ref13]--[@ref18]\] MRI equipment, however, is not always available and its costs are considerable. On the other side, chest X-ray is fast, cheap, relatively safe in terms of radiation exposure, totally non-invasive, and is an easily available form of investigation. With these considerations in mind, the aim of this study was to evaluate in an unselected population undergoing cardiac MRI for clinical reasons the ability of a simple measurement derived from chest X-ray (transverse diameter of the heart shadow \[TDH\]) in detecting LV dilatation and systolic dysfunction, independently measured by cardiac MRI. MATERIALS AND METHODS {#sec1-2} ===================== Patients {#sec2-1} -------- A group of 101 consecutive patients admitted to our Institute and undergoing cardiac MRI and chest X-ray for clinical reasons were studied: 69 patients were males, mean age was 62±14 years. The indications for cardiac MRI were LV ischemic dysfunction, idiopathic cardiomyopathy, acute myo-pericarditis, valvular heart disease, hypertrophic cardiomyopathy, or arrhythmogenic right ventricular dysplasia in 50, 26, 6, 5, 2, and 12 patients, respectively. All patients were under stable clinical conditions at the time of the study. Chest radiography {#sec2-2} ----------------- Chest X-rays (postero-anterior and lateral projections), of patients in the erect position during an inspiratory breath-hold, with rib position on the 6^th^ rib anteriorly and the 10^th^ rib posteriorly, with focus-to-detector distance of approximately 2 m and very short exposure times, were analyzed. A digital system with Charged Coupled Device technology was used. The digital system IMIX-Thorax (Oy IMIX AB, Tampere, Finland), comprising a detector, scintillation camera, optical system, a system for converting X-ray photons, reconstructions computer, and post-processing computer, is capable of displaying the image in about 10 s. In the IMIX-Thorax, the detector system is strictly related to the ARCO COMB column (Arcoma AB, Vaxjo, Sweden). It includes an automatic exposure control system connected to the X-ray generator Medira 2064 (MEDIRA AB, Tampere, Finland), which ensures the constant and correct emission of radiation as a result of the automatic setting of the anode current at the X-ray tube. The chest X-rays were obtained within 2 days of the cardiac MRI study. The films were independently read by two expert radiologists who were blinded to the patient\'s clinical and functional status and level of severity of cardiac disease. For the analysis, a standardized reading grid was used. TDH was measured by drawing a line near the middle of the heart shadow and the spine with a line from the right heart border to that line. Another line from the left heart border farthest from the line in the middle of the heart shadow was added. The two lengths were added together to derive the transverse diameter of the heart \[[Figure 1](#F1){ref-type="fig"}\]. The cardiothoracic ratio (CTR) was also calculated as the ratio between the widest portion of the heart and the diameter of the chest, determined by drawing a line at the level of right leaf of the diaphragm and extending to the inner border of the rib cage on the right and on the left \[[Figure 1](#F1){ref-type="fig"}\]. ![Postero-anterior chest X-ray projection where the measure of the transverse diameter of heart shadow (TDH) is reported. The measure was taken by drawing a line near the middle of the heart shadow and the spine and a line from the right border to that line. Another line from the left heart border, drawn to the middle, was added. The two lengths were added together to derive the TDH.](JCIS-2-25-g002){#F1} Cardiac MRI {#sec2-3} ----------- Cardiac MRI was performed using a 1.5 Tesla whole body scanner (GE Medical Systems, Milwaukee, Wisconsin, USA). A 4-element cardiac phased-array receiver surface coil was utilized for signal reception. A breath-hold segmented-gradient fast-imaging echo, employing steady-state acquisition, triggered with the ECG, was used to evaluate global LV function according to standard parameters. In each patient, a total of 9-12 short-axis views (depending on the LV volumes) and 2 long-axis views (one vertical and one horizontal) were acquired, with a minimum of 30 cine frames for each slice. To measure LV volumes, the endocardial borders were manually drawn in all the short axis end-diastolic and end-systolic images, excluding papillary muscles. End-diastolic and end-systolic LV volumes were calculated and LVEF was derived.\[[@ref19]\] Cut-off values of LV end-diastolic volume (LVEDV) were calculated on the basis of normal values reported in our MRI lab.\[[@ref20]\] Therefore, an absolute LVEDV \>210 mL was considered as abnormal in males and \>150 mL as abnormal in females. The procedures followed were in accordance with the ethical standards of the Institutional Committee on Human Experimentation and with the Declaration of Helsinki of 1974, as revised in 2000. Approval of the Institutional Committee was obtained and each patient gave informed consent for undergoing clinical examination and chest X-ray after cardiac MRI. Statistical analysis {#sec2-4} -------------------- Quantitative data were expressed as mean ± standard deviation, qualitative data as percentage. The relationship between TDH and LV volume or LVEF at MRI was evaluated by least square linear regression analysis and the Pearson linear correlation (r). The cut-off value of the TDH utilized to identify volumes \>150 mL in females and \>210 mL in males was computed using the receiver operating characteristics (ROC) curve and Jouden\'s J. The performance indices of the cut-off value were used to determine sensitivity, specificity, positive and negative likelihood ratio (LR+, LR-), and the area under the ROC curve (AUC). The AUC was estimated by a non-parametric approach. The comparison between females and males for the AUC was made using the method for independent sample. Inter-observer reliability in chest X-ray measurements of two observers was evaluated using the correlation coefficient of Lin,\[[@ref21][@ref22]\] the intra-class correlation coefficient (ICC), and the Bland and Altman method.\[[@ref23]\] The ICC was calculated using a two-way random effects model where people and measure effects were random. A P value \<0.05 was considered to be statistically significant. All tests were two-tailed. The statistical analysis was made by JMP statistical software, SAS Institute Inc, version 4.0.0, and by Stata SE statistical software, StataCorp, release 10.\[[@ref24]\] RESULTS {#sec1-3} ======= Inter-observer variability {#sec2-5} -------------------------- The variability between the values of TDH measured by the two readers was very low. The correlation coefficient of Lin (r = 0,92, 95% C.I. = 0,87--0,97) and the intra-class correlation coefficient (ICC = 0,93, 95% C.I. = 0,86--0,96) were very high. The mean difference between readers was = 0.153 (s.d. = 0.572) and the Bland and Altman 95% Limits of Agreement were 1.275--0.969. As far as the inter-observer variability of thoracic dimensions, the correlation coefficient of Lin was 0,86 (95% C.I. = 0,77--0,95) and the intra-class correlation coefficient was 0,86 (95% C.I. = 0,65--0,94). The mean difference between readers was 0.900 (s.d. = 1.479) while the Bland and Altman 95% Limits of Agreement were -1.999--3.799. As far as CT ratio is concerned, the correlation coefficient of Lin was 0,84 (95% C.I. = 0,74--0,94) and the intra-class correlation coefficient was 0,84 (95% C.I. = 0,58--0,93). A mean difference between readers of -0.019 (s.d. = 0.029) and Bland and Altman 95% Limits of Agreement equal
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2922, 27, 361, 23779, 275, 8920 ]	30's now - I still have a special place for a man that was willing to walk with me through the angst of adolescence. His Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-33160277391080212312012-10-22T14:13:00.001-07:002012-10-22T14:15:17.875-07:00Youth trust youth workers that trust themYou're not superman or wonder woman. At least I'm assuming that to be the case. Even if you were, I've read enough comic books to know that they have some seriously bad days. I do to. Traditionally the early fall is a bit back for us as we slowly get involved in the new pace of life of the students around us. This year however we have been given so many opportunities that we have hit the Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-85983234424679382322012-10-22T13:43:00.000-07:002012-10-22T13:43:01.977-07:00How thought has the power to save or destroy youthIn a recent discussion with a group of youth we talked to them about the power of thought. With the 60,000 plus thoughts that we generate each day, the overwhelming majority of them are negative. Which is not really a surprise to you as you read this. After all if you started cataloging all of your thoughts you would probably start to feel quite negative about yourself, the list you are Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-39373196446347484962012-10-22T13:19:00.001-07:002012-10-22T13:19:29.022-07:00How to think like a teenager. (not really).I have spent many years as a youth worker and before that I was a teen myself. I like to think that I am a relatable guy when it comes to youth issues. However, the only real experts are the youth themselves. To prove this point I recently asked a group of youth workers what the following youth culture slang meant, they didn't get any right. Lets see how you do: Is it a new product fromDanny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-76865380281695323582012-08-01T11:53:00.004-07:002012-08-01T11:59:24.279-07:00Choice: Hit the snooze or get out of bed! A young man questioned me the other day about purpose. He asked me, "Why do you get up in the morning?" I think at some point in our life, each of us must come to grips with a question like this. What is it that we live for? Life is hard. Life isn't fair. And to quote a scene from the TV series House: "Life is pain!" At some points it is easy to ignore. At some points you don't care.Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-71395423351795250342012-07-27T10:08:00.000-07:002012-07-27T10:08:02.342-07:00What to say when you are asked "Where was God?"One of the most difficult things I have experienced in working with young people is watching them fall. I can think of one young guy in particular who asked me when he was elementary school how he could be involved in our student leadership team. After telling him that he wasn't old enough to join that team he walked away disappointed. Years later I have remained in contact with him, only to Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-65780525925188043202012-03-08T14:52:00.001-08:002012-03-08T14:52:45.513-08:00Help a Youth Worker Out Hey, Some friends that work at a website called Chimp have extended an opportunity to me that I had to share with you. As you may or may not know, all of the youth work I do is funded by people, like you, that believe that young people need someone to walk along side them as they try to figure out life. Just in the past few months here are some examples of the types of situations I have Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-72105949645098651852012-01-19T16:49:00.000-08:002012-01-19T16:50:44.880-08:00Exploitation A Reality Of Surburban Youth WorkAs a youth worker, my job entails the opportunity to intersect into the lives of young people wherever they happen to be. I spend time on the streets, in the parks, the alleys, the movie theaters, schools and local coffee shops. Through this work I have encountered many things that I wish that I could unsee. This includes but is not limited to drug deals, suicide attempts, violent exchanges Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-74596806954547180512011-10-13T13:58:00.001-07:002011-10-13T21:05:10.830-07:00I was told, "Those kids are not worth your time." I responed, "thbbbbbb"If you have ever seen the movie, “Chariots of Fire” then you will remember the powerful line made by the Olympic Runner Eric Liddell struggling with his decision to take part in a competition being held on a Sunday, which was taboo in the Christian circles of his day. The quote goes like this: I believe God made me for a purpose, but he also made me fast. And when I run I feel His pleasure. Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-61839737968682181512011-09-27T11:08:00.000-07:002011-09-27T11:08:55.480-07:005 Ways To Go From Good Youth Worker To Great Youth WorkerI realized a long time ago that I do not have all the answers to being a great youth worker. There are so many other people that have traveled the path that are much better than I am. I am thankful for meeting people like Shae Pepper who has some suggestions for youth workers on what could move them from being good - to being great at what they do. Enjoy: I have met some good youth workers Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-86414864625755720382011-09-21T13:33:00.000-07:002011-09-21T13:33:32.982-07:00Book Review: Soul Survivor: How My Faith Survived The Church by Philip YanceyThe title of Philip Yancey’s book caught my eye. Soul Survivor: How My Faith Survived The ChurchThere are lots of things that frustrate me about the intuition of church. The politics.The religiosity.The people.What I was looking for were some answers to how to deal with these issues, what the book was about the people that shaped Yancey’s faith and theology. This was greatly encouraging as I Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-30391157242846864812011-09-19T14:55:00.000-07:002011-09-19T14:58:45.124-07:00Success in youth
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11694, 287, 607, 7046, 285, 344, 37126, 521, 50275, 187, 700, 285, 344, 30443, 949, 253, 50275, 187, 676, 2158, 6385, 76, 50275, 187, 783, 11694, 287, 607, 3543, 275, 521, 25791, 3508, 13779, 50275, 187, 1542, 521, 1175, 270, 1205, 8952, 277, 11131, 50275, 187, 248, 43544, 264, 521, 20971, 1411, 253, 17916, 50275, 187, 395, 344, 16535, 521, 278, 478, 5282, 1959, 50275, 187, 395, 344, 8042, 253, 1391, 1832, 273, 521, 10269, 50275, 187, 79, 6929, 14526, 387, 253, 9970, 273, 253, 50275, 187 ]	toujours gai how did you get the game leg mehitabel i asked her alas she said it is due to the treachery of one of these social swells who is sure one bad actor he was a fussed up cat with a bell around his neck on a ribbon and the look about him of a person that is currycombed and manicured from teeth to tail every day i met him down by the east river front when i was scouting about for a little piece of fish since the high cost of living has become so self conscious archy it would surprise you how close they watch their fish nowadays but what the h dash double l archy it is the cheerful heart that wins i am never cast down for long kid says this gilded feline to me you look hungry i am all of that i says to him i have a vacuum in my midst that is bigger than i am i could eat the fish that ate jonah kid he says you have seen better days i can tell that from looking at you thanks i said what you say is at least half true i have never seen any worse ones and so archy one word led to another until that sleek villain practically abducted me and i went with him on board a houseboat of which he was the pampered mascot such evidences of pomp and wealth archy were there that you would not believe them if i told of them to you poor cockroach that you are but these things were nothing to me for i am a reincarnation of cleopatra as i told you long ago you mean her soul transmigrated to a cat s body i said it is all one archy said she have it your own way reincarnation or transmigration is the same to me the point is i used to be a queen in egypt and will likely be one again this place was furnished swell percy i said the furniture is fine and i could eat some of it if i was a saw mill but where is the honest to g dash d food the eats percy what i crave is some cuisine for my stomach let us trifle with an open ice box for a space if one can be persuaded to divulge the scheme of its interior decoration follow me said this percy thing and led me to a cabin in which stood a table upon which stood viands i have heard of tables groaning archy but this one did not it was too satisfied it purred with contentment in an instant i had eaten a cold salmon who seemed to be toastmaster of the occasion and a whole scuttleful of chef doovers what you mean is hors douvres mehitabel i told her what i mean is grub said she when in walked a person whom i should judge to be either a butler or the admiral of that fleet or maybe both this percy creature who had led me to it was on the table eating with me what do you think he did what would any gentleman friend with a spark of chivalry do what but stand by a lady this percy does nothing of the kind archy he immediately attacks me do you get me archy he acts as if i was a stray cat he did not know and he was protecting his loving masters food from my onslaughts i do not doubt he got praise and had another blue ribbon for his heroism as for me i got the boot and as i went overboard they hit me on the limb with a bottle or an anchor or something nautical and hard that archy is why i limp but toujours gai archy what the h dash double l i am always merry and always ladylike mine archy has been a romantic life and i will tell you some more of my adventures ere long well au revoir i suppose i will have to go and start a pogrom against some poor innocent little mouse just the same i think that mehitabel s unsheltered life sometimes makes her a little sad # JULY 24 ## _Galoshes for Cockroaches_ do you know of any firm that specializes in galoshes for cockroaches it would be a graceful deed if you were to give me a pair for my birthday or a little motor boat would do i tried to get on the subway train to go up town the other day but a cascade caught me on the steps and carried me onto the tracks when i stopped floating i was in brooklyn # AUGUST 6 ## _A Poem in the Kipling Manner_ 1 "Where have you been so long? And what on earth do you mean by coming in here soused?" we asked Archy as he zigzagged from the door to the desk. He climbed onto the typewriter keys and replied indignantly: soused yourself i havent had a drink and yet i am elevated i admit it i have been down to a second hand book store eating a lot of kiplings earlier poetry it always excites me if i eat a dozen stanzas of it i get all lit up and i try to imitate it get out of my way now i feel a poem in the kipling manner taking me And before we could stop him he began to butt on the keys: the cockroach stood by the mickle wood in the flush of the astral dawn We interrupted. "Don't you mean Austral instead of astral?" Archy became angered and wrote peevishly: i wrote astral and i meant astral you let me be now i want to get this poem off my chest you are jealous if you were any kind of a sport at all you would fix this machine so i could write it in capitals it is a poem about a fight between a cockroach and a lot of other things get out of my way im off the cockroach stood by the mickle wood in the flush of the astral dawn and he sniffed the air from the hidden lair where the khyber swordfish spawn and the bilge and belch of the glutton welsh as they smelted their warlock cheese surged to and fro where the grinding floe wrenched at the headlands knees half seas over under up again and the barnacles white in the moon the pole stars chasing its tail like a pup again and the dish ran away with the spoon the waterspout came bellowing out of the red horizons rim and the grey typhoon and the black monsoon surged forth to the fight with him with three fold might they surged to the fight for they hated the great bull roach and they cried begod as they lashed the sod and here is an egg to poach we will bash his mug with his own raw lug new stripped from off his dome for there is no law but teeth and claw to the nor nor east of nome the punjab gull shall have his skull ere he goes to the burning ghaut for there is no time for aught but crime where the jungle lore is taught across the dark the afghan shark is whining for his head there shall be no rule but death and dule till the deep red maws are fed half seas under up and down again and her keel was blown off in a squall girls we misdoubt that we ll ever see town again haul boys haul boys haul. "Archy," we interrupted, "that haul, boys, is all right to the eye, but the ear will surely make it hall boys. Better change it." you are jealous you let me alone im off again the cockroach spat and he tilted his hat and he grinned through the lowering mirk the cockroach felt in his rangoon belt for his good bengali dirk he reefed his mast against the blast and he bent his mizzen free and he pointed the cleats of his bin nacle sheets at the teeth of the
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326, 310, 1146, 8653, 275, 841, 327, 14, 14396, 20134, 19184, 15, 187, 34, 2007, 16182, 16965, 562, 14, 1171, 14, 4152, 941, 323, 253, 28802, 2362, 15, 1723, 13, 253, 6322, 1854, 323, 253, 562 ]	the cannabis sector of hostile consolidation transactions with companies using their stock as currency. To protect shareholders from such coercive activity, Origin House recently announced the signing of voluntary voting support agreements. Read the full news release Q. Do you see your position as middle-men between growers and retailers to be a limited and possibly temporary strategy as compared to vertically integrated businesses? Our business strategy goes beyond being a middle-man between growers and retailers. We are laser-focused on building a strong foundation based on a unique strategy that will position Origin House to be the leading global house of brands. We’ve already built a strong framework that consists of manufacturing, distribution, logistics capabilities and added talented people to our team to ensure success for our brand partners. We will progressively internalize authentic brands and accelerate growth, replicating the blueprint in new markets. Stay tuned for more, in 2019! Q. With many US states legalizing cannabis, does Origin House have a current plan in place to enter into other states with the same approach that has made it possible to acquire the dominant position it holds in California? We are always There is a growing trend within the cannabis sector of hostile consolidation transactions with companies using their stock as currency. To protect shareholders from such coercive activity, Origin House recently announced the signing of voluntary voting support agreements. Read the full news release here Our business strategy goes beyond being a middle-man between growers and retailers. We are laser-focused on building a strong foundation based on a unique strategy that will position Origin House to be the leading global house of brands. We’ve already built a strong framework that consists of manufacturing, distribution, logistics capabilities and added talented people to our team to ensure success for our brand partners. We will progressively internalize authentic brands and accelerate growth, replicating the blueprint in new markets. Stay tuned for more, in 2019!We are always looking and exploring new markets, but we will enter when it makes business sense for us to do so. We’re keeping a keen eye open and when the regulations change and permit us to trade on other exchange, we will explore the opportunity Q. How does the Ontario government’s decision to allow only 25 cannabis stores impact your plans for 180 Smoke? 180 Smoke already has strong retail capabilities for the expanding nicotine vape e-juice manufacturing and cannabis hardware business which generated $11.7 million in net revenue in 2018, up 50% from $7.8 million in 2017. The limitation of 25 licenses does not impact our plans for 180 Smoke. We will continue to expand our footprint and as the Canadian cannabis landscape continues to evolve, we look forward to adding cannabis retail to our 180 portfolio.# Elixir Python definitions for qemu exec(open('commonkconfig.py').read()) Q: Bundle unable to locate/execute gems for ruby app if installed through Chef I am trying to deploy a ruby app through chef. I have installed ruby and rubygems through rvm. When I do a bundle install --deployment manually on the shell I get all the bundles downloaded to vendor/bundle location and everything works fine. But when I do the same with chef using bash resource I get error messages mentioned below. I feel like some issue with the PATH or environmental variables. Through chef also it downloads all the gems but when I open the shell and check I get errors. Please note - chef recipes executes without any errors. bundle exec rake db:create RAILS_ENV=production (in /home/xyz) rake aborted! undefined method `[]' for nil:NilClass /home/xyz/Rakefile:4:in `require' (See full trace by running task with --trace) # ruby -v ruby 1.9.2p290 (2011-07-09 revision 32553) [x86_64-linux] # gem -v 1.8.1 bundle -v Bundler version 1.0.15 # gem env RubyGems Environment: - RUBYGEMS VERSION: 1.8.1 - RUBY VERSION: 1.9.2 (2011-07-09 patchlevel 290) [x86_64-linux] - INSTALLATION DIRECTORY: /usr/local/rvm/gems/ruby-1.9.2-p290 - RUBY EXECUTABLE: /usr/local/rvm/rubies/ruby-1.9.2-p290/bin/ruby - EXECUTABLE DIRECTORY: /usr/local/rvm/gems/ruby-1.9.2-p290/bin - RUBYGEMS PLATFORMS: - ruby - x86_64-linux - GEM PATHS: - /usr/local/rvm/gems/ruby-1.9.2-p290 - /usr/local/rvm/gems/ruby-1.9.2-p290@global - GEM CONFIGURATION: - :update_sources => true - :verbose => true - :benchmark => false - :backtrace => false - :bulk_threshold => 1000 - REMOTE SOURCES: - http://rubygems.org/ bash "bundle install" do user "root" cwd "/home/xyz/" code <<-EOH source /etc/profile.d/rvm.sh rvm use 1.9.2-p290 --default /usr/local/rvm/gems/ruby-1.9.2-p290/bin/bundle install --path vendor/bundle /usr/local/rvm/gems/ruby-1.9.2-p290/bin/bundle exec rake db:create RAILS_ENV=production EOH end This is the first time I am deploying any ruby app, I have googled a lot and tried many solutions but I get more and more errors but no solutions. Any kind of help would be greatly appreciated. Thanks, Imran A: So I believe the reason why you are having some issues with ruby installed by RVM has to do with the nature of linux + shells. RVM masks a lot complexity underneath when it presents you with a list of ruby builds that you can install on your system. Simple answer is RVM ( similar to rbenv ) works by hooking into your environment's PATH... This is a very detailed explanation provided by Sam Stephenson here: How do RVM and rbenv actually work? but I digress. My guess is that your RVM installation is made for an individual user, eg user who has home directory /home/xyz/. At this point, I think your problem is the following: You installed RVM via Single-User installation( Details here: https://rvm.io/rvm/install ). When you installed RVM, they probably made you do this step here: echo "source $HOME/.rvm/scripts/rvm" >> ~/.bash_profile. This step adds a command into your.bash_profile so that on each new session/terminal window, your user ( in this case, user xyz ) reads in information on how to run/use RVM. The bash resource in chef isn't actually using the same shell that you use to connect and run commands. My thought is that, if you run something like: bash 'install_ruby_stuff' do cwd ::File.dirname(/home/xyz) code <<-EOH source /home/xyz/.rvm/scripts/rvm bundle exec rake db:create RAILS_ENV=production EOH end I have a feeling it might work a bit better. If that doesn't work, run which bundle and figure out exactly where rvm installs the bin stub for the bundle command, then replace bundle above, with /path/to/bundle and that might help as well. Each bash resource call in chef is essentially treated like a separate shell, so any PATH or ENV variables that you need, need to be defined within the same context that the bash resource is called. Hope this helps you a bit! The extraction of critical events relevant to a broadcast sporting event is a manual and time-consuming task. This is typically performed by video annotators who view a recording of the event and manually scrub through the video to annotate the video in order to break the video into segments for future use. Time codes embedded in the video are typically used as the mode of identifying the segment of the video that is relevant. Accordingly, the ability to extract these types of data and synchronize with video is a challenge. Sporting activities contain repeating events of fine granularity, such as clocks and timers, which are independent of the play action, as well as events that are dependent on the action of the players. One currently used broadcast methodology for enhancing the fan experience is to embed this data by rendering a graphical representation of it into the video program. For example, an on-screen dashboard typically shows information such as scores, game-clocks, shot-clocks, etc. Recently, there has been an increase in the amount of data that is being displayed in these on-screen dashboards. A further methodology sends out-of-band data for the sporting event. However, the transmission path for the out
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3727, 273, 253, 44787, 30721, 1387, 3066, 6776, 5837, 407, 2983, 273, 253, 6561, 40299, 14164, 281, 253, 12344, 22021, 6315, 762, 29747, 4702, 273, 247, 2620, 14, 6441, 7455, 19870, 32739, 15, 23449, 432, 6153, 2317, 875, 253, 16504, 40197, 285, 253, 21725, 2670, 13, 436, 5700, 20096, 326, 253, 767, 5164, 14429 ]	value (231 mM^−1^s^−1^) than Z-Lys-Lys-AMC, which seems to be due to a decrease in K~m~. Noteworthy, the introduction of the PABA linker was not tolerated by cathepsin L as the analog of 19 containing Phe instead of Lys in P^2^ (Z-Phe-Lys-PABA-AMC) was not converted by this enzyme. Therefore, the combination of the two Lys residues with the self-destructive PABA linker makes 19 to a substrate which is cleaved by cathepsin B with excellent selectivity over cathepsins L and S. Probe 19 was also effectively cleaved by lysates of HeLa cervical tumor cells. Pretreatment of HeLa cells by the cell-permeable pro-inhibitors E64d (8b) or CA074Me (9b), which inhibit several cysteine cathepsins or selectively cathepsin B, respectively, after intracellular activation by esterases, resulted in a complete blocking of the conversion of 19. Fluorescence microscopic observation of live HeLa cells in the presence of Z-Arg-Arg-AMC or Z-Phe-Arg-AMC did not result in the detection of any cellular fluorescence. Contrary to this, the three-component probe 19 containing the PABA linker led to blue fluorescent cells, while no intracellular fluorescence could be visualized in the presence of CA074Me (9b) or E64d (8b). Similar results were obtained when the HeLa cells were replaced by the Her2-positive breast cancer cell line MDA-MB-231-H2N. These results clearly indicate that 19 undergoes cathepsin B-dependent activation inside the cells and that the PABA linker obviously facilitates membrane permeation of the peptidic probe. When Z-Phe-Lys-PABA-AMC was investigated in the same manner, it was revealed that its cellular activation was only completely blocked by treatment with E64d, while the presence of CA074Me resulted in considerable residual cellular fluorescence. These observations suggest that the latter probe is activated by cathepsin B and other cysteine cathepsins, which is in accordance to results from kinetic investigations and cell lysate experiments. Furthermore, Z-Phe-Lys-PABA-AMC compromises cell viability in both cell lines as assessed by the MTT assay, while 19 and the ordinary two-component probe Z-Arg-Arg-AMC are well-tolerated (Chowdhury et al., [@B44]). ![Fluorogenic substrate-based probes for targeting of cysteine cathepsins containing only one luminophor. Emitting fluorophoric moieties are shown in red, moieties that act as spacer are highlighted in green and additional targeting moieties are shown in blue.](fchem-03-00037-g0008){#F8} While 7-amino-4-methylcoumarin is an advantageous fluorophore for protease activatable probes due to its small size, its blue fluorescence and rather short excitation wavelength are adverse properties. Alternatives can be found by rhodamine derivatives, which exhibit two amino groups attached to the xanthenyl system and offer the opportunity of longer wavelength excitation/emission together with high quantum yields for fluorescence. Peptidic moieties can be attached to the two amino groups of rhodamines which will result in fluorescence attenuation and illumination upon protease-mediated cleavage (Leytus et al., [@B127]; Rothe et al., [@B187]). However, a drawback of such probes is that consecutive removal of two peptide residues will result in mono-acylated and completely deacylated rhodamine species which will differ in their fluorescence properties. To tackle that problem, Fujii et al. ([@B76]) developed activatable probes based on "reduced" rhodamine green (rhodamine green is also known as rhodamine 110), in which the carboxy group is replaced by a hydroxymethyl residue. Typical for xanthene dyes, this hydroxymethyl rhodamine green (HMRG) exists in solution in a ring-chain tautomeric equilibrium between a non-fluorescent spirocyclic form and a highly fluorescent quinoid open form. At physiological pH, the equilibrium lies on the side of the open form, which is characterized by favorable photophysical properties such as high fluorescence quantum yield (Φ~fl~ = 0.81) and long fluorescence lifetime (τ = 3.8 ns) (Sakabe et al., [@B198]). Mono-acylation of one of the amino groups will stabilize the non-fluorescent spirocyclic form and thus result in strong attenuation of fluorescence. Fujii et al. aimed to exploit this principle for the design of cathepsin B-activatable probes in the context of optical tumor imaging. To this end, they attached the Z-Phe-Arg (as realized in compound 20) and Z-Arg-Arg moiety to HMRG. The extinction coefficient of free HMRG is more than 400 times higher than that of 20 (at λ~max~ = 501 and 497 nm, respectively). The kinetic evaluation toward the cathepsins L, B, S and K was done at pH 5.5 and pH 7.4, to simulate intralysosomal and cytosolic/extracellular pH-values, at a single substrate concentration of 3 μM. Cathepsin B rapidly converted 20 at both pH-values, whereas the cleavage of Z-Arg-Arg-HMRG was only effective at pH 5.5. At this pH conversion of 20 by cathepsin L was slower than that by B, whereas Z-Arg-Arg-HMRG was cleaved with much lower velocity. The cleavage of 20 catalyzed by cathepsin L at pH 7.4 was very slow, probably due to the fact that cathepsin L undergoes irreversible inactivation at pH-values greater than 6.5 (Brömme et al., [@B31]). Compound 20 was also converted by cathepsin K at both pH-values but was no effective substrate of cathepsin S. Incubation of 20 with SK-OV-3 human ovarian tumor cells resulted in microscopically visible cell-associated fluorescence, which was attenuable by treatment with the broad-spectrum cell-permeable fluoromethylketone inhibitior Z-Phe-Phe-FMK (1a). It was concluded that cleavage of 20 occurs intracellularly, because the treatment with membrane-impermeable inhibitor CA074 (9a) was of negligible influence. Intraperitoneal injection of 20 into mice bearing peritoneally implanted SK-OV-3 tumors, a model for human ovarian cancer, resulted in a clear visualization of the tumor nodules with a tumor-to-background ratio of 4.2 The stability of 20 in peritoneal liquid has been confirmed independently and the green HMRG fluorescence colocalized with the tumor nodules when SK-OV-3 cells transformed with red fluorescent protein (RFP) were implanted. The disadvantages of the discussed non-quenched cathepsin-responsive probes are due to the fact that the emission wavelengths of their fluorophores are too short for in vivo imaging. Fluorophores with emission wavelengths in the near infrared (NIR) range can be found within the class of cyanine dyes, which are employed in the FRET-based probes 16 and 17 discussed above. Despite these fluorophores are characterized by high extinction coefficients, acylation-based attenuation of fluorescence is difficult to realize, in contrast to luminescent groups on the basis of aromatic amines such as AMC and HMRG. To overcome this drawback, Kisin-Finfer and Shabat ([@B114]) set out to develop fluorophores where three consecutive carbons of the polymethine chain of cyanine dyes are part of a napthalene ring. To this end, they reacted 4-hydroxynaphthalene-1,3-dicarbaldehyde with two equivalents of 3-(2,3,3-trimethyl-3H-indol-1-ium-1-yl)propane-1-sulfonate in a Knoevenagel-type condensation. The obtained product is a representative of the so called "donor-two-acceptor" NIR dyes, referring to the electron-donating hydroxyl group and the two indolium acceptor moieties (Karton-Lifshin et al., [@B105]), and shows a pH-dependent fluorescence with an emission wavelength of 740 nm and a large Stokes shift of 80 nm. Notably, only the deprotonated phenolate form is fluorescent. In consequence, acylation of the OH group will lead to strongly attenuated fluorescence, which can be exploited to design hydrolase-sensitive probes as it has been realized in compound 21 for imaging of cathepsin B (Kisin-Finfer et al., [@B113]). Considering the steric demand of the fluorophore, its conjugation to the cathepsin-responsive Z-Phe-Lys moiety was done via a self-immolative linker which resembles in part the PABA linker contained in 19 (Chowdhury et al., [@B44]). In difference, a N,N\'-dimethylethylenediamine-carbonyl spacer follows the PABA element (Shabat et al., [@B212]). Analogously to 19, cathepsin B-mediated release of the aromatic amine will result in the formation of imino quinone methide and carbon dioxide. This reaction step triggers in turn the release of the phenolic hydroxyl group via cyclisation by attack of the secondary amine nitrogen to the carbamate carbon under concomitant formation of a five-membered cyclic urea. Apart from creating space between the fluorophore and the cleavage site, this strategy ensures that the two functional entities
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for sure. On that day, the 70-year-old Harris County Sheriff’s sergeant met with a deputy who later tested positive for COVID-19, the disease caused by the coronavirus. The fever arrived a few days later - low. Fatigue. But such symptoms weren’t unusual for Scholwinski, who has scarred lungs that make him cough sometimes. But days later, he still had a fever. “We had some high hopes,” Rynda said. “But that evening, his fever came back up.” Now, her husband is fighting for his life in a bed in an ICU at Memorial Hermann’s hospital in the Woodlands. He is one of thousands of first responders sickened by COVID-19 nationally, including dozens in Harris County. Police families know the inherent dangers in their jobs - car crashes, fights with suspects, getting shot - but the coronavirus is different. Just going to work means walking into the line of fire of an unseen enemy. So far, 30 Harris County deputies have become ill, and the number will grow. “We have the same caution and fears as the general public, except we don’t have the option to stay home,” said Harris County Deputies’ Organization President David Cuevas. “We have to go to work, continuously do our job and we’re fighting an enemy we can’t see.” Deputies also still have to run the county jail, a crowded facility holding more than 7,500 inmates in close proximity. Experts fear an outbreak tearing through the jail. A dozen jail employees have already come down with the virus. Three inmates have tested positive; dozens more are presumed ill, and 850 others are in quarantine after possible exposure. “It’s challenging for our personnel,” Sheriff Ed Gonzalez said. “And the anxiety …. They’re seeing teammates become ill, seeing that a number of first responders are starting to die around the country. It’s all very new and scary to us.” RELATED: First responders can’t social distance. Some are getting sick. And departments say it could strain responses A caretaker Rynda also fell ill - and had to spend four days in bed. Even getting up to let Cissy, her Yorkie, outside exhausted her. Raymond brought her water, and Gatorade. “He always took care of me,” she said. It has been that way ever since they first met 35 years ago, when he was working at the apartment complex where she lived and slowly began courting her. Lean and gregarious, he seemed to know everyone. He’d retired from the insulation installation business he’d created and was working at several apartment building. But his heart was at the sheriff’s office. When she cut her hand on shattered glass, and needed surgery, he drove her to and from the appointment. He brought her meals, and flowers. She thought he was taking pity on her. He had other plans. On a camping trip a year after they met, he asked her to marry him. By then, she’d long since fallen for him, for the way he always looked out for her, and the way he always tried to help out the elderly residents in the complex where she lived. On his days off, he sometimes worked at the marine division of the sheriff’s office, where he’d volunteered as a reserve deputy in 1979. He decided to work there full-time soon after they married. It was nerve-wracking for her. When he worked nights, she always woke up early, looking for him on the morning news being interviewed from a crime scene. If he was on TV, that meant he hadn’t got hurt. This feels different. “They go through training how to learn how to approach a vehicle to make a stop, how to answer a door when they’re going to a domestic violence call” she said. “But you can’t even train against this.” Scholwinski works at the sheriff’s office’s station in District 2, where he helps run public safety town halls with residents. He works long hours, helping frustrated residents and attending community meetings, his District 2 colleagues said. “He loves people. That’s why he loves this job,” District 2 Capt. Mike Koteras said. RELATED: From swing sets to adult novelty shops, 311 calls report social distancing violators in Houston area His colleagues describe him as the go-to guy when there’s a problem. He’s the one on his hands and knees helping friends fix a broke-down car, or pulling out his wallet to help, whether he can afford it or not. The one who shows up hours early to cook turkeys for deputies working on Thanksgiving, and then stays hours late cleaning up. “He’s got time for everybody,” said Sgt. Joe Halm. “No matter if he’s in a hurry, he’ll stop, he will talk to people.” Now his friends and fellow deputies are watching, stunned, as he fights for his life. Test results After Scholwinski started to feel sick he drove to Baytown to get tested. The result came back positive. Rynda tested positive a few days later. They were encouraged at first, even as they both battled mild fevers and fatigue. Rynda counted the days. Each day was an emotional roller coaster, fevers rising, then breaking. They prayed, and tried to stay positive. “The longer it got, the more hopeful I became it wouldn’t get into his lungs,” she said. “But I was very wrong about that.” His fever, in spikes, inexorably ticked upward. “We were yo-yos,” Scholwinski said. THE FIRST FIFTY: What we can learn from the Houston-area people first diagnosed with COVID-19 On Sunday, March 29, breathing became more difficult. They called his pulmonologist, who told them to head to the hospital. They drove from their home in Inverness Forest to the hospital later that morning, holding hands along the way. When she stepped out of her Denali, she told the waiting nurses they both were sick with COVID-19. Her mask muffled her voice, and so she took a step closer to the nurses, so they could hear her better. They waved her back. A nurse went inside, and brought out identity bracelets for Scholwinski -- and a wheelchair. A nurse eased Raymond into it, and warned Rynda that because of the virus, she wouldn’t be able to visit. She watched as they began wheeling him toward the hospital doors. She told him she loved him. To fight with all his might. To hurry home. He told her he loved her, and that he would do his best. Then the doors shut behind him. “That’s the last time I saw him,” she said, her voice catching. After Scholwinski arrived at the hospital, doctors started giving him oxygen, Rynda said. Doctors prescribed hydroxychloroquine, the medicine President Donald Trump has touted. By the next day, doctors told Rynda that Raymond wasn’t responding to the medication anymore. The couple tried to talk every day, but she did most of the speaking. On Thursday, doctors called. Raymond needed to go on a ventilator, a potentially life-saving intervention, but one that often signals a rapid decline. Rynda’s mind raced. She wondered what it would mean for her husband. “Every little step he takes backwards means it’s that many more before he can step forward,” she said. On Tuesday, Scholwinski remained in an artificially induced coma, on dialysis. The virus has made it difficult for his body to expel the carbon dioxide it produces, so the machine is helping pull the gas from his blood. “He’s hanging in there,” Rynda said. “He has a lot to
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2896, 253, 6818, 14, 19016, 13, 11960, 777, 434, 5621, 574, 851, 2114, 1097, 2652, 316, 300, 729, 285, 1503, 26824, 297, 343, 13, 1223, 13, 281, 253, 6146, 13, 5685, 10824, 574, 20698, 745, 271, 9054, 2983, 387, 26096, 42416, 13, 810, 1776, 253, 2846, 327, 253, 6818, 14, 339, 19894, 15, 3083, 6339, 1024, 9355, 247, 9974, 3587, 9268, 2584, 611, 28017, 13, 533, 2067, 1897, 273, 11792, 9313, 3531, 253, 13939, 715, 47156, 572, 19803, 2731, 13, 17190, 247, 19086, 281, 253, 4254, 15, 2732, 253, 3216, 574, 13831, 13, 253, 20003, 23347, 616, 9222, 327, 721, 4565, 13, 342, 253, 767, 4289, 4430, 2149, 9411, 273, 253, 34981, 14, 19521, 73, 9251, 8260, 17729, 718, 13454, 7457, 12194, 29894, 13, 2190, 731, 767, 2120, 11100, 29894, 285, 247, 11100, 23493, 15, 9394, 91, 5356, 13, 275, 1859, 273, 253, 16400, 9054, 34385, 13, 11960, 777, 434, 1821, 6786, 247, 1643, 1980, 34158, 13, 48928, 981, 7754, 3056, 1190, 327, 253, 2800, 16565, 13, 285, 3839, 17355, 10397, 285, 1030, 1808, 318, 275, 253, 12194, 10581, 15, 11706, 13, 841, 1980, 23991, 84, 760, 5783, 253, 4067, 5685, 34390, 15, 4129, 597, 8058, 673, 285, 969, 13253, 1037, 8936, 281, 253, 10968, 46426, 13, 253, 20003, 812, 417, 6455, 841, 1980, 34158, 715, 271, 15942, 29709, 984, 387, 253, 9560, 2774, 597, 20296, 253, 3309, 4757, 15, 3308, 13, 3738, 875, 4223, 285, 4565, 275, 512, 5871, 1411, 8663, 5901, 3684, 3815, 253, 10968, 46426, 9606, 253, 41954, 2264, 273, 38362, 13, 21874 ]	some thirty thousand soldiers were sentenced to death, with perhaps twenty thousand of those executed, most in the last year or so of the war, as against forty-eight executed in all the German armed forces during World War I. If National Socialist ideas failed to inspire a will to resist, then Nazi terror would be used instead. For the average soldier, the war had become, in the most concrete sense, a battle for survival. With the Germans driven back across the Dnieper, the Red Army had attained the original goal of its summer offensive but now moved to exploit the fruits of its victory. Drawing on the local population for replacements--some eighty thousand men were drafted from the liberated areas and thrown into the battle--and concerned that, if given time, the Germans would take advantage of the river line to stalemate the war, the Soviets bounced the river in a number of places and established bridgeheads on the west bank as launching pads for future operations. Although the Dnieper, with its broad channel, high bluffs on the western side, and swampy eastern bank, afforded the strongest natural defensive line in western Russia, Hitler's stubborn insistence on holding out east of the river had deprived the Germans of most of its advantages. Not only had their strength been sapped, but work on constructing defenses along the river had also lagged. Many Landsers, encouraged by the talk of an Ostwall, were dismayed to find on crossing the river that little had been built and they were left in the open. "We had expected," wrote one, "to find the Ostwall behind the Dnieper. Not even trenches were there." This shock to the morale of the exhausted German forces was compounded by the awareness of the vast mismatch in strength between the opposing sides. Although on paper Manstein had sixty divisions at his disposal, in reality most had the strength only of a regiment and some not even of a _Kampfgruppe_ (battle group). In early October, Army Group South had only about one thousand combat troops per division, fewer than three hundred operational tanks and assault guns, and not quite six hundred aircraft for itself and Army Group A to its south. Manstein himself admitted gloomily at the end of October that the combat strength of his troops, exhausted by ceaseless battle for months, had "sunk so low... that as a result of our insufficient manpower in the front lines the enemy can punch through anywhere he assembles sufficient forces." Instead of organizing a defense along the river line, however, he had to try, with inadequate forces, to eliminate or contain the numerous Soviet bridgeheads, even as the enemy sought to exploit its vast numerical preponderance by launching several attacks simultaneously along the front. Of these bridgeheads, the ones ultimately most dangerous were north of Kiev at Liutezh and Chernobyl. The Red Army had originally hoped, in a daring blow using massed armor and airborne troops, to burst out of the Bukrin bridgehead to the south of the Ukrainian capital in late September and seize the city in a sweeping move to the west and north. Although this had resulted in a fiasco, Vatutin skillfully moved his troops, under cover of effective camouflage measures, to the northern bridgeheads. Following a massive artillery barrage, Soviet forces on 3 November assaulted the thin German defenses at Liutezh, at the same time breaking out of the bridgehead near Chernobyl. Within two days, the Fourth Panzer Army front had been shattered, and, lacking reserves of any kind, it was helpless to slow the enemy advance. By the sixth, Kiev had fallen, and Soviet forces were pushing westward almost unhindered. Troops of the First Ukrainian Front, storming out of the Chernobyl bridgehead, raced toward the city of Korosten at the border of Army Groups Center and South, having blasted a sixty-mile-wide gap between the two army groups just south of the Pripet Marshes, a no-man's-land that the Germans could cover only with reconnaissance troops and patrols. Although the giant swamps of the Pripet offered the Second Army to the north some flank protection, it was primarily controlled by partisan bands, which left the danger that the Soviets might be able to roll up the soft underbelly of the Second Army from the south. Fortunately for the Germans, the various Soviet, Ukrainian, and Polish partisans operating in the Pripet fought each other as much as the German occupier, so an immediate threat failed to materialize, but the situation remained unstable. More pressing was the danger from Red Army troops driving out of Liutezh on the key railroad junction of Fastov, thirty miles southwest of Kiev, which controlled the lines supplying Army Group South's central sector. Its fall on the seventh raised the possibility that the army group might be enveloped, especially since the southern wing of the front had been under assault since early October. With his efforts to repair the situation on the northern end of his sector frustrated by Hitler's insistence on defending the great bend of the Dnieper to the south, Manstein flew to Fuhrer Headquarters on the ninth to demand its evacuation, a move that would shorten the front considerably and free units for use in the north. To Manstein, there seemed little operational point to holding on to the Dnieper bend, especially since Zaporozhye and Dnepropetrovsk had already been lost in mid-October. In addition, Soviet troops had shattered the front of the Sixth Army (Army Group A) at Melitopol on 23 October and reached the Black Sea in early November, trapping the Seventeenth Army in the Crimea. As always, however, Hitler insisted that the manganese ore mines near Nikopol could not be given up without great harm to the armaments effort, nor could the Crimea be abandoned since it would provide the Soviets airfields from which to attack the vital Rumanian oil fields. Ironically, the Fuhrer's intransigence had been reinforced late in October by Manstein himself. In expectation of receiving five fresh panzer divisions from the west, the OKW having decided that the danger of an Allied invasion had passed, he proposed an attack, reminiscent of his Kharkov success, to cut off the exposed Soviet forces. By now, however, the urgent danger in the north had pushed aside all thoughts of such an operation, but neither the field marshal nor Gehlen, who warned of a "collapse of the eastern front," proved able to change Hitler's mind. It was, he said, a risk that would have to be taken, although he did allow Manstein to use some of the newly arrived panzer divisions in the area of the Fourth Panzer Army. One of these was the newly raised Twenty-fifth Panzer Division, just arrived from France after a series of misadventures that had seen it originally sent to the right flank of the army group before being hurried north, with the result that its equipment was scattered over hundreds of miles. Although not trained for fighting on the eastern front, and lacking much of its heavy weapons--it was, as one author noted ironically, a panzer division without panzers--it was the only unit available to slow the Soviet advance at Fastov. Against Guderian's vehement objections, the Twenty-fifth Panzer, with as much strength as it could muster, was thrown on the seventh into a counterattack at Fastov in an attempt to regain the rail juncture. By the time its full complement of armored vehicles arrived two days later, it had already suffered such losses that it was unable to retake the city, an outcome that sent Hitler into a rage. More importantly, in throwing into battle a unit clearly unready for combat, the German leadership had departed from its key principle. In contrast to the Soviets, who had squandered many newly formed divisions by throwing them prematurely into combat, the Germans had allowed units to train behind the front to gain experience before being sent into battle. Still, despite being sacrificed, the Twenty-fifth Panzer had performed a vital task: it had slowed the Soviet advance at Fastov and gave Manstein time to organize a counterattack. Launched on 15 November, the counterstrike was carried out by General Hermann Balck's Forty-eighth Panzer Corps, which had assembled almost three hundred armored vehicles. Typically at this stage, since the Germans had not yet completely abandoned the idea of regaining the initiative, it aimed at not just pinching off the Soviet advance but ultimately recapturing Kiev. By the twenty-third, Balck's forces had retaken both Brusilov and Zhitomir, while, to the north, German troops had beaten off an enemy attack at Korosten, regaining the city on the twenty-seventh. Manstein now planned a strike directly east toward Kiev, but several days of steady rain turned the roads into muddy quagmires, forcing a halt to the operation. After the ground had frozen, the Germans renewed their assault on 6 December, with the two hundred armored vehicles of the Forty-eighth Panzer Corps assailing nine Soviet armies, among them two full tank armies and a tank corps. Amazingly, in view of the overwhelming enemy superiority, Balck's men achieved a few local victories, recapturing Radomsyl on the sixteenth, and generally spreading anxiety and consternation in the Soviet rear. Still, these local triumphs only confirmed the larger German dilemma. Although they proved time and again tactically superior to the Soviets, the Germans could not convert these local victories into an operational breakthrough because at the crucial moment they lacked the necessary strength. Thus, although between August and December in all operations against Army Group South alone the Soviets suffered the staggering total of 417,323
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1603, 17, 582, 428, 393, 1906, 24915, 18, 1603, 69, 1035, 3214, 1594, 13, 2805, 10689, 426, 393, 2059, 1352, 3813, 13, 407, 8755, 905, 5616, 7857, 14, 2941, 14, 2941, 5290, 370, 82, 5, 8696, 327, 247, 669, 3214, 1594, 2911, 1402, 15, 2367, 73, 9337, 393, 7536, 724, 187, 187, 3463, 11506, 905, 8560, 23, 15, 21, 5290, 627, 1057, 417, 2226, 247, 2624, 1127, 273, 669, 3214, 1594, 1352, 3813, 13, 352, 310, 2590, 326, 187, 187, 1447, 5528, 23, 15, 21, 696, 1310, 30780, 6796, 1217, 57, 2023, 393, 3214, 1926, 6796, 1217, 57, 6580, 12310 ]	gamma}\|_{[s_{1}, s_{2}]}) = s_{2} - s_{1} = \left\| \int_{\tilde{x}(s_1)}^{\tilde{x}(s_2)} \frac{m(t)}{\sqrt{m(t)^{2} -\nu^2}}\,dt \right\|_.$$ Since $\tilde{x}'(s) \not= 0$ for all $s \in (s_{1}, s_{2})$ with $\tilde{x}(s) \in [t_{1}, t_{2}]$, we may choose the numbers $s_{1}$ and $s_{2}$ in such a way that $$\tilde{x}(s_{1}) = t_{1}, \quad \tilde{x}(s_{2}) = t_{2}$$ or $$\tilde{x}(s_{1}) = t_{2}, \quad \tilde{x}(s_{2}) = t_{1}.$$ Thus, we see that $$\label{lem6.3-1} { L(\tilde{\gamma}) \ge \int_{t_{1}}^{t_{2}} \frac{m(t)}{\sqrt{m(t)^{2} -\nu^2}}\,dt }_.$$ Since $${ \frac{m(t)}{\sqrt{m(t)^{2} -\nu^2}} \ge 1 + \frac{\nu^{2}}{ 2 m(t) \sqrt{m(t)^{2} -\nu^2} } }_,$$ we have, by (\[lem6.3-1\]), $${ L(\tilde{\gamma}) \ge t_{2} - t_{1} + \frac{\nu^{2}}{2} \int_{t_{1}}^{t_{2}} \frac{1}{m(t)\sqrt{m(t)^{2} -\nu^{2}}}\,dt }_.$$ ${\hfill \Box}$ \[lem2009-03-03\] For any $q \in \Cut (\partial X) \cap (X \setminus \partial X)$ and any ${\varepsilon}> 0$, there exists a point in $\Cut (\partial X) \cap B_{{\varepsilon}} (q)$ which admits at least two $\partial X$-segments. The above lemma is well-known in the case of the cut locus of a point (see [@B]), which can be proved similarly. However we will give a proof of the lemma totally different from it (see Section \[sec:appe\]). \[prop6.4\] Let $\mu_{0} :[0, \infty) {\longrightarrow}X$ be a $\partial X$-ray guaranteed by the assumption above. If $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies $$\label{prop6.4-con1} { \int_{0}^{\infty} \frac{1}{m (t)^{2}}dt = \infty }_,$$ or $$\label{prop6.4-con2} { \liminf_{t \to \infty} m(t) = 0 }_,$$ then, any point of $X$ lies in a unique $\partial X$-ray. In particular, $\partial X$ is totally geodesic in the case where (\[prop6.4-con1\]) is satisfied. Choose any point $q \in X \setminus \partial X$ not lying on $\mu_{0}$. Let $\mu_{1} : [0, d(\partial X, q)] {\longrightarrow}X$ denote a $\partial X$-segment with $\mu_{1} (d(\partial X, q)) = q$. For each $t > 0$, let $\gamma_{t} :[0, d(q, \mu_{0}(t))]{\longrightarrow}X$ denote a minimal geodesic segment emanating from $q$ to $\mu_{0} (t)$. From Proposition \[weak\] and the triangle inequality, it follows that there exists a generalized open triangle $(\partial {\widetilde}{X}, {\widehat}{\mu}_{0}(t), {\widehat}{q}\,) = ({\widehat}{\gamma}_{t}, {\widehat}{\mu}_{0}^{(t)}, {\widehat}{\mu}_{1})$ in ${\widetilde}{X}$ corresponding to the triangle $(\partial X, \mu_{0}(t), q) = (\gamma_{t}, \mu_{0}\|_{[0, \,t]}, \mu_{1})$ in $X$ such that $$\label{prop6.4-length1} d(\partial {\widetilde}{X}, {\widehat}{\mu}_{0}(t)) = t, \quad d(\partial {\widetilde}{X},{\widehat}{q}\,) = d(\partial X, q),$$ and $$\label{prop6.4-length2} L(\,{\widehat}{\gamma}_{t}\,) \le d(\mu_{0}(t), q) \le t + d(q, \mu_{0}(0))$$ and that $$\label{prop6.4-angle} \angle(\partial X, q, \mu_{0} (t)) \ge \angle(\partial {\widetilde}{X}, {\widehat}{q}, {\widehat}{\mu}_{0} (t)).$$ Here $\angle(\partial X, q, \mu_{0} (t))$ denotes the angle between two sides $\mu_{1}$ and $\gamma_{t}$ joining $q$ to $\partial X$ and $\mu_{0} (t)$ forming the triangle $(\partial X, \mu_{0}(t), q)$. From Lemma \[lem6.3\], (\[prop6.4-length1\]), and (\[prop6.4-length2\]), we get $$\begin{aligned} \label{prop6.4-1} t + d(q, \mu_{0}(0)) &\ge L(\,{\widehat}{\gamma}_{t}\,)\notag\\[2mm] &\ge { t - d(\partial X, q) + \frac{\nu_{t}^{2}}{2} \int_{d(\partial X,\, q)}^{t} \frac{1}{m(t)\sqrt{m(t)^{2} -\nu_{t}^{2}}}\,dt }_.\end{aligned}$$ where $\nu_{t}$ denotes the Clairaut constant of ${\widehat}{\gamma}_{t}$. By (\[prop6.4-1\]), $$\label{prop6.4-2} { d(\partial X, q) + d(q, \mu_{0}(0)) \ge \frac{\nu_{t}^{2}}{2} \int_{d(\partial X,\, q)}^{t} \frac{1}{m(t)^{2}}\,dt }_.$$ First, assume that $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies (\[prop6.4-con1\]). Then, it is clear from (\[prop6.4-2\]) that $${ \lim_{t \to \infty} \nu_{t} = 0 }_.$$ Hence, by (\[clairaut\]), we have $$\label{prop6.4-3} { \lim_{t \to \infty} \angle(\partial {\widetilde}{X}, {\widehat}{q}, {\widehat}{\mu}_{0} (t)) = \pi }_.$$ By (\[prop6.4-angle\]) and (\[prop6.4-3\]), $\gamma_{\infty} := \lim_{t \to \infty} \gamma_{t}$ is a ray emanating from $q$ such that $${ \angle\,(\gamma'_{\infty}(0), - \mu'_{1}(d(\partial X, q))) = \pi }_.$$ This implies that $q$ lies on a unique $\partial X$-segment. Therefore, by Lemma \[lem2009-03-03\], $q$ lies on a $\partial X$-ray. Now, it is clear from Lemma \[lem6.2\] that $\partial X$ is totally geodesic. Second, assume that $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies (\[prop6.4-con2\]). Then, there exists a divergent sequence $\{ t_{i} \}_{i \in {\ensuremath{\mathbb{N}}}}$ such that $$\label{prop6.4-4} { \lim_{t \to \infty} m(t_{i}) = 0 }_.$$ From (\[clairaut\]), we see $$\label{prop6.4-5} \nu_{i} \le m (t_{i}),$$ where $\nu_{i}$ denotes the Clairaut constant of ${\widehat}{\gamma}_{t_{i}}$. Hence, by (\[prop6.4-4\]) and (\[prop6.4-5\]), $$\liminf_{t \to \infty} \nu_{t} = 0$$ holds. Now, it is clear that there exist a limit geodesic $\gamma_{\infty}$ of $\{\gamma_{t_{i}}\}$ such that $\gamma_{\infty}$ is a ray emanating from $q$ and satisfies $\angle\,(\gamma'_{\infty}(0), - \mu'_{1}(d(\partial X, q))) = \pi$. Therefore, by Lemma \[lem2009-03-03\], $q$ lies on a $\partial X$-ray. ${\hfill \Box}$ By Proposition \[prop6.4\], there does not exist a cut point of $\partial X$. Therefore, it is clear that \[cor6.4\] If $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies
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1472, 816, 1264, 15, 1623, 619, 2118, 449, 309, 458, 7760, 281, 619, 4669, 13, 417, 6179, 281 ]	ma'am." Eleven. Less than half of what we started the day with. No telling how many of the eleven were wounded. Probably most, though Mac's team seemed to move well, so maybe they'd avoided the worst of it. The two lift aircraft came in slower than the fighters, but still fast. The trick to spotting them was to look ahead of where you heard the noise. By the time you heard them, they'd already moved from that location. I tried to find one, only to watch a yellow-and-orange fireball light the sky. A split second later the loud _fwaaaap_ of a large pulse weapon cut through the night. More distortion of light and sound. A ship had exploded before we heard the weapon that killed it. One of the landing craft had disintegrated. Light streaked across the sky in golden fingers. Missiles. At least six, maybe more. Another flash, then another less than a second behind it. Both fighters hit, one explosion eclipsing the other. A sinking, queasy feeling grabbed at my gut. They'd just eliminated our rescue with a big pulse weapon and a bunch of surface-to-air missiles. But the enemy didn't have those weapons—they weren't supposed to, anyway. Those missiles hadn't been small shoulder-fired SAMs, either. They had high-end stuff. Dangerous. I put the implications of what just happened behind me for a minute and scanned the sky. We still had one transport left, and with our reduced numbers, they had space to carry us all out if they could get to us. Another missile streaked into the sky like a fiery sword. The second transport flung flares from its hull and dove hard, but the missile had locked in. A golden blossom of death lit the sky and the transport spun toward the ground, spitting flames. A quirk of fate set its descent almost directly toward the source of the missile that killed it. "Ejects," said Mac, softly so it didn't carry. I scanned the sky and found the pilots with my night-vision optics. "Got them. Looks like they both popped clear. You think anyone else popped? From the other birds?" The chutes drifted toward Cappa in a controlled fall. "Don't know, sir," said Mac. "I doubt it. They flashed pretty big." "Yeah," I said. Baxter stood and hurried over to me, taking a knee. "Sir, what the fuck do we do?" Her voice rose a few notes. "Call it in," I said. "Sir, the jammer. We've got no off-planet commo again." Shit. "They must have moved in a mobile." Even as I said it, I doubted it. The enemy had pulled back when the fighters attacked. Nothing could have survived that barrage. They had to be jamming the satellites directly. That meant a bigger problem, but one for another day. We had to live through this, first. My mind scrambled for a solution. "There's no way that Cappa Base doesn't know what's going on now." I kept my voice level, hoping it would help Baxter do the same. "They'll send help. Wait for the next ships to come into range, then signal them in. You'll know they're close, because they're going to blow the crap out of that anti-aircraft site before they get here, now that they know about it." "It will take at least twenty-five or thirty minutes until they arrive," she said. She was right, and we didn't have thirty minutes. With the ships down, the enemy would move back in. "Let's go," I said. "Where, sir?" she asked. "Anywhere but here. Let's not give them an easy target." "We should head for the downed pilots," said Mac. "Perfect," I answered. "They'll have beacons, not the markers we've got. Transmitters that broadcast without satellites. All the pilots do. And if there's one thing you can guarantee, it's that the squadron isn't going to leave their fellow pilots down here." "Yes, sir," said Baxter, her voice steady, the moment of indecision gone. She was going to make it in our business, assuming she lived through this fight. That's what the good ones did. If they panicked, they got over it fast. "Move now, two groups of four, three in the middle," radioed Baxter. "We've got tail," I told her. Mac grabbed two of the soldiers who came with him to round out our team and linked the others up with another element. We started moving fifteen seconds later, three wedges, our trailing group inverted so the point faced back. If the fighters hadn't destroyed the enemy in front of us, we'd know soon. And if we made it past that, I hoped that the downed pilots didn't shoot at us thinking we were enemy. We didn't have any way to speak to them, and trusting scared pilots on the ground was risky. Another problem for later. Even with night vision, the branches slapped against my face plate, and low scrub grabbed at my feet and ankles. It kept us to a quick walk, and we still made more noise than I'd have liked. _Thirty minutes_. Less than five minutes later, four rockets slammed the ground to our front, throwing dirt, rock, and branches, shaking our already wobbly legs. They knew we were moving. They had to. They only missed by a hundred meters. By unspoken accord, we picked up our pace. Someone might fall in a hole or smash a knee on a rock, but it beat being cut in half by hot metal. Another barrage ripped through the trees, off to the right this time, farther away. An enemy machine gun tore through the night, also off the mark. The bullets hunted through the woods, meandering slowly, looking for a target without knowing where to start. Recon by fire. They wanted us to shoot back. I flipped open the channel to tell everyone to hold their fire. Too late. The man beside me let off a three-round burst. "Cease fire." I tried to keep my voice calm on the net. No use yelling about it now. "I had his position marked," said the soldier who fired. She sounded confused more than defensive. "We don't want to give away _our_ position," I called over the net. "We need to move. Now." Two heavy weapons and at least a dozen smaller ones raked the ground around us, ripping chunks out of trees and flinging up dirt, flashing off of rocks. Without firing back, we had nothing to keep the enemy's head down. Even from three hundred meters, if they kept enough bullets flying, they'd get lucky soon enough. "Keep moving," I radioed. "My team will stop and pour down some fire for thirty seconds, then catch up." Mac flashed me a thumbs-up to show me that he heard. He grabbed one of the other soldiers and physically put her into position behind a head-sized rock. He put the other behind a tree. That didn't leave much cover for him or me, so we grabbed the ground and got as low as we could. "Fire when I do," I radioed. "Slow and steady. Thirty seconds, twenty rounds. Explosive if you've still got them. Pick targets if you can, if not, try to silence the bigger guns." I took a deep breath and silently counted to three for no particular reason. I squeezed my first shot off in the direction of one of the heavy guns, then fired three more in a pattern right around it. The staccato burst of my own team firing close by drowned out the sound of the enemy. Vaguely I sensed bullets getting closer. Something cracked into my left shoulder, wrenching my weapon from that hand. A burst of molten fire jolted my shoulder joint, then my whole arm went numb. I didn't think the bullet penetrated my armor, though I had no way to tell in the dark. The force of the bullet did enough, even with the protection I had from my gear. I shook my numb hand, trying to find some feeling. Belatedly, I rolled over twice to a new position in case someone had homed in on my location. Always have to remember the fundamentals. A dozen bullets ricocheted off the rock our soldier hid behind, throwing sparks into the air and momentarily screwing with my night optics. I aimed in the general direction of the fire with my one working arm and squeezed off half a dozen useless shots before rolling again. "Ten seconds until we move," I said. "Shoot 'em if you got 'em." The pops around me intensified. No fire came from behind the rock, so I crawled on my belly toward the soldier's position, pulling with my good arm. She lay still, her helmet shattered. I grabbed her and rolled her toward me, but I knew even before I finished moving her that we'd lost her. Too many cracks in the helmet, too many bullets. Shit. I didn't even know her name. I grabbed her ammo. "Let's go," I called. "We're just three. On my move." I leaped to my feet, not waiting to
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84, 18, 14, 18, 94, 187, 22928, 187, 187, 510, 1263, 11205, 281, 7277, 253, 43150, 3165, 285, 14834, 6973, 323, 9943, 2255, 342, 440, 681, 37787, 36486, 2556, 281, 9355, 1659, 273, 4201, 13, 326, 310, 13, 4675, 18213, 44869, 13, 4201, 23221, 390, 387, 1728, 15, 50253, 6949, 2908, 2622, 18213, 285, 4201, 13, 4438, 273, 4201, 13, 12214, 1309, 18213 ]	Conflict of interest statement. None declared. Supplementary Material ====================== ###### \[Supplementary Data\] We thank Dr Zhenbao Yu for valuable discussion and advice, Linhua Zhang, Meiqun Wu and Denis L'Abbe for technical assistances. [^1]: The names of siMVPs were designated according to their positions in 1.3kb-MVP cDNA clone. [^2]: Only the sense strand is shown. [^3]: HeLa cells were transfected with 60 ng pEGFP, 1.2 ng pRLSV40 (Rluc) and 0.1nM siMVPs synthesized in vitro. Three independent assays each in triplicate were performed. The potency of siMVPs was calculated by the ratio of EGFP/Rluc against the control of unrelated siRNA (siHB1). You are here UFC 214: Lawler vs Cerrone Betting Odds I hope you like violence because Robbie Lawler and Donald Cerrone are scheduled to clash at UFC 214 in an all-action bout that has “fight of the year” written all over it. We haven’t seen Lawler since he dropped the welterweight title to Tyron Woodley last July while Cerrone is coming off a tough loss to Jorge Masvidal. ‘Ruthless’ Robbie Lawler opened as a -145 favorite with ‘Cowboy’ Cerrone coming back at +115. Assuming this line stays steady, this will be the first time Cerrone has entered a fight as an underdog since his title loss to Rafael dos Anjos in December 2015. Lawler bloomed late in his career, taking several years to accumulate experience that has been a valuable asset to his style. He is more crafty than flashy and looks to counter-strike with his fast, heavy hands when striking. Lawler is vicious in the clinch and his good takedown defense allows him to punish opponents who try to shoot. Cerrone wants to break down his opponent with a mixture of pace and vicious leg kicks. Very few fighters in the UFC can cut down an opponent the way that Cerrone can. The Denver, Colorado native is also a lethal submission specialist if the fight goes to the mat. The handicapping, sports odds information contained on this website is for entertainment purposes only. Please confirm the wagering regulations in your jurisdiction as they vary from state to state, province to province and country to country. Using this information to contravene any law or statute is prohibited. The site is not associated with nor is it endorsed by any professional or collegiate league, association or team. OddsShark does not target an audience under the age of 18. Please visit gambleaware.co.uk or gamcare.org.uk for guidelines on responsible gaming.###### Strengths and limitations of this study - This retrospective study reveals the first Australia-wide evidence on the relative safety of planned birth in hospital, a birth centre and at home. - It analyses linked data on the outcomes for women with uncomplicated pregnancies and their infants in all eight Australian states and territories. - Careful data screening eliminated most causes of obstetric complexity, resulting in three cohorts with equivalent levels of risk. - Inconsistency between state-based datasets limited the number of confounding variables available for analysis. - Insufficient data on changes in planned birth place prior to labour hampered identification of intrapartum transfers and analysis of the relationship between intended and actual place of birth. Introduction {#s1} ============ In Australia, most births occur in hospitals (97.5% in 2015), with some variation across the eight states and territories (for example, 91% in the Australian Capital Territory to 99% in Victoria).[@R1] Women with uncomplicated pregnancies and who are planning hospital births in the public health system receive antenatal care from hospital-based midwives and doctors, sometimes within continuity of care models and often in partnership with local general practitioners (GPs). Hospital midwives attend their labour and birth, with medical involvement as required or in line with local protocols. In the private health system (where 25% of births take place), women receive antenatal care from private obstetricians or midwives employed by obstetricians. Hospital midwives attend their labour and birth and the obstetrician attends during the labour and is usually at the birth.[@R2] There are some differences across Australia in the way care is provided, especially the local guidelines and the choices available to women. The availability of different models of care varies across the country. While most births take place in hospital labour wards or birth suites, a small proportion (1.8% nationally) take place in midwife-run birth centres.[@R1] In Australia these birth centres are typically co-located with hospitals (similar to alongside midwifery units in other countries) although a small number of stand-alone birth centres exist.[@R4] Birth centres typically provide midwifery continuity of care to women with uncomplicated pregnancies in a home-like environment and are well integrated into the health system. Less than 0.3% of Australian births take place at home, ranging from 0.1% of births in New South Wales to 0.6% in the Northern Territory.[@R1] Most planned home births are attended by midwives working in private practice, some of whom also attend women in birth centres and hospitals. The integration of private homebirth services varies across the country. A small number of hospitals and birth centres offer home births through the public health system.[@R6] An evaluation of the outcomes of publicly funded models providing homebirth showed that the rate of stillbirth and early neonatal mortality was low, at 1.7 per 1000 births. However, the sample size did not have sufficient power to generate a conclusion about safety.[@R7] We have conducted a systematic review to examine maternal and perinatal outcomes associated with planned place of birth for women with uncomplicated pregnancies in high-income countries.[@R8] In this analysis of 28 studies from 13 countries, women who planned hospital births had significantly higher rates of perineal trauma and instrumental/caesarean birth than those who planned other birth places. Overall, there was no significant difference in the odds of intrapartum stillbirth according to place of birth (compared with planned hospital births, planned homebirth: OR=0.94; 95% CI 0.76 to 1.17; planned birth centre OR=0.66; 95% CI 0.32 to 1.34) or in early neonatal deaths (planned home birth OR=1.00; 95% CI 0.78 to 1.27; planned birth centre 0.87; 95% CI 0.29 to 2.61). Previous Australian state-based studies into place of birth have showed variation in findings. In New South Wales (the most populous state accounting for around 30.9% of births),[@R9] women without pregnancy complications who planned a home or birth centre birth had significantly higher proportions of normal birth than those planning hospital births (home 97.4% vs birth centre 86.0% vs hospital 73.9%). There was no significant difference in neonatal mortality although the overall sample size (n=2 58 161, including only 742 planned home births), had insufficient power for these relatively rare outcomes. In South Australia (SA) (297 192 planned hospital births and 1141 (0.38%) planned home births), another study found lower intervention rates and equivalent perinatal death rates in home births compared with hospital births. However, the odds of an intrapartum fetal death were significantly higher among planned home births (two deaths in the planned home birth group; adjusted OR (AOR) 7.42; 95% CI 1.53 to 35.87). This study included some women with recognised risk factors in the home birth group including twins.[@R10] Large-scale studies in other countries show similar perinatal outcomes between births planned at home and in hospitals (and birth centres where these exist) with some differences for primiparous women.[@R11] There is less controversy about birth centres compared with homebirth. Data from Australian birth centres indicate lower rates of maternal morbidity,[@R15] intervention, preterm birth and low birth weight compared with hospital births for women with similar risk profiles.[@R16] One study identified no significant differences by birth place in perinatal mortality[@R16] and another reported lower perinatal mortality in birth centre births, although based on actual rather than intended birth place.[@R17] A smaller hospital-based study found no significant difference in caesarean section rates between the birth centre and labour ward for women with uncomplicated pregnancies.[@R18] Two other birth centre studies reported higher rates of spontaneous vaginal birth and lower rates of adverse infant outcomes (neonatal intensive care unit (NICU) admission, low birth weight) compared with hospital births.[@R19] The safety of place of birth continues to be questioned in Australia.[@R21] To generate evidence to assist policy makers, health practitioners and pregnant women and their families to make informed decisions about place of birth, we undertook a national study combining data from all eight Australian jurisdictions to examine the outcomes for women with uncomplicated pregnancies related to three different birth settings. This is the first national study on the comparative safety of different planned birth settings in Australia. Aim and objectives {#s1-1} ------------------ The study aimed to compare the perinatal and maternal outcomes for Australian women with uncomplicated pregnancies according to planned place of birth, that is, hospital labour wards, birth centres or at home. Outcomes investigated included normal labour and birth, mode of birth, interventions during labour
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Further independence of ProQ from ProP is demonstrated by the fact that ProQ is still associated with ribosomes in the absence of proP and proU mRNAs ([Figure 5](#pone-0079656-g005){ref-type="fig"}). Though further studies are needed to definitively determine the function of the ribosomal association of ProQ, it is not unreasonable to propose a role for ProQ in translation initiation. Under non-dissociating conditions, we observe the highest concentration of ProQ in fractions corresponding to 70S and polysome species, but there is a modest, yet consistent, increase in signal under the peak corresponding to 30S particles, the first particle to bind during initiation ([Figure 1A](#pone-0079656-g001){ref-type="fig"}). This 30S localization is confirmed under dissociating conditions ([Figure 1B](#pone-0079656-g001){ref-type="fig"}). We present data showing that ProQ can bind tightly to mRNA in vitro ([Figure 4](#pone-0079656-g004){ref-type="fig"}), and mRNA integrity is necessary for robust ribosome association ([Figure 3](#pone-0079656-g003){ref-type="fig"}). Thus, ProQ is ideally positioned to function in translation initiation of its mRNA targets, perhaps by facilitating the interaction between 30S particles and these as-yet unidentified mRNAs. The authors wish to thank Dr. Titus Franzmann for training and technical assistance with tryptophan fluorescence experiments and Dr. Stefan Walter for assistance with ProQ-mRNA binding data analysis. [^1]: Competing Interests:The authors have declared that no competing interests exist. [^2]: Conceived and designed the experiments: DTS RZ. Performed the experiments: DTS RZ. Analyzed the data: DTS. Contributed reagents/materials/analysis tools: DTS. Wrote the manuscript: DTS. Critical reading and approval of the final manuscript: DTS RZ. Fitness recovery and compensatory evolution in natural mutant lines of C. elegans. Deleterious mutation accumulation plays a central role in evolutionary genetics, conservation biology, human health, and evolutionary medicine (e.g., methods of viral attenuation for live vaccines). It is therefore important to understand whether and how quickly populations with accumulated deleterious mutational loads can recover fitness through adaptive evolution. We used laboratory experimental evolution with four long-term mutation-accumulation (MA) lines of Caenorhabditis elegans nematodes to study the dynamics of such fitness evolution. We previously showed that when homozygous mutant populations are evolved in large population sizes, they can rapidly achieve wild-type fitness through the accumulation of new beneficial or compensatory epistatic mutations. Here, we expand this approach to demonstrate that when replicate lineages are initiated from the same mutant genotype, phenotypic evolution is only sometimes repeatable. MA genotypes that recovered ancestral fitness in the previous experiment did not always do so here. Further, the pattern of adaptive evolution in independently evolved replicates was contingent upon the MA genotype and varied among fitness-related traits. Our findings suggest that new beneficial mutations can drive rapid fitness evolution, but that the adaptive process is rendered somewhat unpredictable by its susceptibility to chance events and sensitivity to the evolutionary history of the starting population.[Intraoperative Optical Coherence Tomography - an Overview of Current Clinical Data for the Application in the Anterior and Posterior Segments]. Intraoperative optical coherence tomography (iOCT) represents another milestone in ocular imaging technologies. Now, for the first time, high resolution OCT images are available not only pre- or postoperatively, but also intraoperatively. In recent years, there have been significant advances in iOCT technology - from hand-held probes and mounted systems towards iOCT systems which are fully integrated into the surgical microscope and which provide seamless integration into the workflow. These systems offer high-resolution, intraoperative OCT scans in real-time and provide additional information on microstructures of the retina or the cornea. These findings may even lead to a modification of surgical strategies. Like any other new technology, iOCT technology still has some limitations, such as shadowing from instruments and the lack of eye tracking systems. Therefore, the current state of iOCT technology still requires some skill to track surgical maneuvers in real time. Further research and development will help to solve these limitations in the future. However, even if not required for all surgical procedures, iOCT imaging can already improve safety and control in many surgical procedures on the anterior and posterior segments. This has already been shown in several studies and case series. Particularly in the surgery of vitreomacular traction, peeling of epiretinal membranes (ERM peeling) and macular hole surgery, iOCT offers significant added value. It improves the visualisation of transparent structures and helps to avoid the usage of dyes. In addition the success of the surgical maneuvers can be investigated intraoperatively. In lamellar keratoplasty and glaucoma surgery too, iOCT improves precision and safety. Moreover, iOCT technology may help to achieve further insight into ocular pathologies and a better understanding of the impact of surgical maneuvers on visual rehabilitation. Further prospective studies are however required to evaluate the usefulness of iOCT in various surgical procedures on both, the anterior and posterior segments.Spengler wrote as if decline was inevitable, as if the cycle he described – in which each civilization experiences its spring, summer, autumn, winter – were as unavoidable as the spinning of the earth. Once societies pass their great creative stage and the logicians, rationalists, and bureaucrats arrive on the scene, there is no turning back. Having lost a sense of purpose, civilizations lurch outward to find meaning. They get caught up in a series of disastrous wars, propelled forward to doom by history’s cosmic beat, power for power’s sake, blood for blood’s. The big political news in the United States of America over the last few days is that the leading candidate for the Republican Party nomination for next year’s Presidential election, a business mogul by the name of Donald Trump, has called for a ban on Muslims being allowed into the United States. The mainstream Republican Party candidates and personalities have, by and large, denounced Trump’s bigoted call. He has even been referred to as a “fascist demagogue.” But, Trump’s lead in the polls derives from the fact that the things he has been saying, no matter how distasteful to more enlightened Americans, appeal to the Republican base. It may be said that what we now know as the United States began almost four hundred years ago with the arrival from Plymouth, England, of a sailing ship called the Mayflower north of Virginia on the northeastern coast of America. This was 1620 Anno Domini, and the passengers were English men and women who felt they were experiencing a religious persecution in England which they considered unbearable. They were called “Pilgrims,” also “Puritans.” They were Christians being persecuted by Christians. The majority population of what we now know as the continental United States at the time when the Pilgrims landed was, of course, Native American tribes. But, in 1565 the Spanish had established St. Augustine in what we now call Florida, St. Augustine being considered the oldest city in the United States. It would be interesting to establish when precisely it was that the United States became a majority white population. When the United States of America declared its independence from England in 1776, the U.S. was just thirteen former British colonies. Today, the United States consists of fifty two states and a much larger land mass than at independence in 1776. The United States did not acquire the so-called Louisiana territory from France until 1803, Napoleon Bonaparte having given up his Western Hemisphere ambitions and pretensions after the French were defeated in Haiti by Toussaint, Dessalines, and other former African slaves. This Louisiana territory is about two fifths of the present day United States. In 1776, again, almost all the area west of the Mississippi River was controlled by various Native American tribes. And, in the South and the Southwest, the Spanish were prominent from Florida through Texas and New Mexico all the way to Arizona and California. America, then, is a new phenomenon compared to Great Britain, Germany, France, and so on. Before I proceed, let me say this. Inside the bastions of pure white supremacy, Europeans like the Spanish and the Italians are not really considered “white.” This is partly because the North Africans were so powerful in places like modern Italy, Spain, and Portugal for so many centuries, beginning with Hannibal, I suppose, and extending all the way up to 1492, when the Moors were expelled from Spain after seven centuries of hegemony. The elite in the United States are called WASPs – White Anglo-Saxon Protestants. The Irish, Jewish, Italian, and other populations now part of America’s white majority, came from Europe, afterwards Eastern Europe, in waves of immigration which began taking place in the latter half of the nineteenth century. In America today, for whatever it’s worth, “white” is equated with “Christian,” hence there is a racial undertone to Donald Trump’s assault on Muslims. (In white America, Arabs are definitely not considered white.) You see what we are dealing with here. Now, at some point after World War II the United States essentially became an empire, insofar as its power and wealth were concerned, and today, in a bit of desperation, there are significant elements in the United States who want to declare the American empire a “white” empire, and, through Trump, they are declaring this to the world. As planet earth’s imperial superpower, the United States interacts with the world in various ways. Perhaps the most strateg
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Statistical fluctuations are reduced with the help of a guiding wavefunction, whose free parameters are determined dynamically during the simulation. In order to keep the variance of observables finite as the simulation proceeds, it is necessary to simulate a population of $K$ [walkers]{} (field configurations at fixed time), and extrapolate the results to $K\to\infty$. We focus on the case $V = \lambda_2\phi^2 + \lambda_0\phi$; strong coupling always predicts supersymmetry breaking; weak coupling predicts unbroken supersymmetry for $\lambda_0<0$; according to Ref. [@Witten2], unbroken supersymmetry should be accompanied by a nonzero $\langle\phi\rangle$ (parity breaking). We presented preliminary results, obtained by GFMC, for intermediate couplings in Ref. [@lattice2001]; our aim is to extend the study towards the continuum limit and to larger lattices. Perturbative computations show that $$\lambda_2 \approx a \lambda_2^{\rm ren}, \quad \lambda_0 \approx a \lambda_0^{\rm ren} + a \lambda_2^{\rm ren}\frac{1}{2\pi}\ln\left(aM\right), \label{eq:evol2_L}$$ where $\lambda_i$ is the adimensional lattice bare coupling, $\lambda_i^{\rm ren}$ is the renormalized (continuum) coupling, with dimension of $m^1$, defined at the mass scale $M$, and $a$ is the lattice spacing. We study, as $\lambda_2\to 0$, the trajectory $$\lambda_0={\lambda_2\over2\pi}\,\ln(4\lambda_2), \label{eq:trajectory}$$ corresponding to a perturbative RG trajectory (\[eq:evol2\_L\]); the effect of $\lambda_0$ is small in the range we considered, therefore we expect Eq. (\[eq:trajectory\]) to be a reasonable approximation to a true RG trajectory. We estimate the correlation length from the exponential decay of the connected correlation function $G_d=\langle\phi_n\phi_{m}\rangle_c$ averaged over all $n,m$ pairs with $\|m-n\|=d$, excluding pairs for which $m$ or $n$ is closer to the border than (typically) 8. In our formulation, fermions are staggered and even/odd $d$ correspond to different channels. -8mm -8mm We begin with the discussion of the case $V=0.35\,\phi^2+0.02$, for which we have obtained the statistics of $4{\times}10^6$ GFMC iterations. The even-$d$ channel is plotted in Fig. \[fig:xieven,l2=0.35\]; it is very difficult to extract a correlation length, presumably because $\phi$ has a very small overlap with the lightest state of the channel, and the value of $\xi$ quoted in Fig. \[fig:xieven,l2=0.35\] should be considered tentative. The odd-$d$ channel, plotted in Fig. \[fig:xiodd,l2=0.35\], is much cleaner, and it is possible to estimate $\xi$ with a good precision. For the other values of $\lambda_2$, the situation is similar but with larger errors; we have a statistics of at least $10^6$ iterations, which we are increasing to $4{\times}10^6$. The values of $\xi_{\rm odd}$ follow nicely the expected behavior $\xi\propto1/\lambda_2,$ as shown in Fig. \[fig:xioddlog\]: the entire range $0.088\le\lambda_2\le0.35$ seem to be in the scaling region, with $\lambda_2=0.5$ a borderline case. The values of $\xi_{\rm even}$ have very large errors, and it is hard to draw any conclusion from them. -8mm We measure the ground state energy $E_0$ along the trajectory (\[eq:trajectory\]); the measurements have a very small statistical error, ranging from 1% for $\lambda_2=0.044$ (where $E_0/L\approx10^{-3}$) to 0.1% for $\lambda_2=0.5$. We extrapolate to $L\to\infty$ and $K\to\infty$ fitting $E_0/L$ to the form $${E_0/L} = {\cal E}_0\left(1 + {c_L/L} + {c_K/K}\right). \label{eq:E0/L}$$ $E_0/L$ is plotted in Fig. \[fig:E0log\]: it seems to behave $\propto\lambda_2^{5/3}$, while naïve scaling would predict $\propto\lambda_2^2$. The value of $E_0/L$ (disregarding this puzzling exponent) and the lack of any signal for a breakdown of parity (like a double-peaked distribution of $\phi$) strongly hint that the trajectory (\[eq:trajectory\]) belongs to the phase with broken supersymmetry and zero $\langle\phi\rangle$. We are repeating the computation for trajectories with smaller $\lambda_0$. -8mm [9]{} J. Kogut, L. I. Susskind, Phys. Rev. D11 (1975) 395; J. Kogut, Rev. Mod. Phys. 51 (1979) 659. W. von der Linden, Phys. Rept. 220 (1992) 53. M. Beccaria, M. Campostrini, A. Feo, Nucl. Phys. B (Proc. Suppl.) 106-107 (2002) 944. M. Beccaria, M. Campostrini, A. Feo, hep-lat/0109005. E. Witten, Nucl. Phys. B188 (1981) 513. E. Witten, Nucl. Phys. B202 (1982) 253. [^1]: Presented by M. Campostrini The Latest on the Con Man and His Victims (Fyre: The Greatest Party That Never Happened, Netflix) Note: This post was updated on Sept. 24, 2019: These days, when I’m not rewatching Forensic Files on TV, I’m restreaming Fyre: The Greatest Party That Never Happened on my MacBook. Happier times: Fyre investor Carola Jain, Billy McFarland, Jason Bell (not involved with Fyre), and Ja Rule You can see the Netflix Fyre documentary half a dozen times and pick up something new every time. Blue-eyed bandit. The 97-minute original production tells the excruciating story of a music festival founder who believed that a high-profile social media campaign would magically compensate for severe unpreparedness and underfunding. Billy McFarland promised ticket buyers private-jet transportation, ahi sliders, luxurious villas on a nirvana-like private island in the Bahamas, and performances by 10 major recording artists. The Fyre Festival failed on all accounts. Most of the well-to-do millennials who spent upward of $4,000 per person to experience a luxurious bacchanalia ended up receiving no-frills flights, sleeping on rain-soaked mattresses in FEMA tents on a gravelly construction site, scrounging for food, and listening to excuses from McFarland instead of performances by Blink-182 and Tyga. Infernal mess. In a way, even the locale for the festival didn’t exist. McFarland said he had purchased Pablo Escobar’s island, where organizers shot a promotional video featuring such supermodels as Emily Ratajkowski and Hailey Baldwin — who then publicized the upcoming event via Instagram — but the sale never actually happened. The organizers then arranged to have the festival on Great Exuma, a Bahamian island that isn’t private, so they photoshopped out parts that weren’t. Before Fyre, McFarland, then 25, probably imagined himself as the next under-30 entrepreneur headed for the Forbes 400 list. Note the FEMA tents on the Netflix film promo Card game. Described as charming, intelligent, and persuasive, the towering and slightly tubby New Jersey native first made a name for himself by establishing Magnises, a credit card whose fee included perks like discounted Beyoncé tickets and social events at a Manhattan townhouse. That venture, targeted at millennials, got off to an impressive start, then fizzled after not delivering on promises. But it didn’t get enough bad press to cloud McFarland’s image as a young visionary. It was the Fyre Festival flameout that exposed McFarland as a fraud for all the world to see. Virtually every major news media outlet covered the April 2017 disaster. Schadenfreude samba
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The series expansion of a composition of fully matricial analytic functions {#sec13.10} --------------------------------------------------------------------------- This section records the fact that the noncommutative series expansion of a composition of fully matricial holomorphic maps coincides with the composition of the series. More precisely we have the following proposition. [Proposition.]{} [Let $B(j)$ $(j = 1,2,3)$ be Banach spaces and let ${\Omega}(j)$ be affine fully matricial $B(j)$-sets containing the origin. Let further $g: {\Omega}(1) \to {\Omega}(2)$ and $f: {\Omega}(2) \to {\Omega}(3)$ be fully matricial holomorphic maps which send the origin to the origin. With the notations of [\[sec13.9\]]{} let $$\begin{aligned} {\alpha}_k &\in {{\mathcal L}}(B(1)^{{\widehat}{\otimes}k},\ B(2)), \\ {\beta}_k &\in {{\mathcal L}}(B(2)^{{\widehat}{\otimes}k},\ B(3)), \\ {\gamma}_k &: {{\mathcal L}}(B(1)^{{\widehat}{\otimes}k},\ B(3))\end{aligned}$$ be multilinear maps so that $$\begin{aligned} (d^kg_n)(O_n)[{\beta},\dots,{\beta}] &= k!{{\mathcal Z}}({\alpha}_k)_n({\beta}) \\ (d^kf_n)(O_n)[{\beta},\dots,{\beta}] &= k!{{\mathcal Z}}({\beta}_k)_n({\beta}) \\ (d^k(f_n \circ g_n))(O_n)[{\beta},\dots,{\beta}] &= k!{{\mathcal Z}}({\gamma}_k)_n({\beta}).\end{aligned}$$ Then we have $${\gamma}_k = \sum_{\substack{i_1 + \dots + i_l = k \\ i_j \ge 1}} {\beta}_l \circ ({\alpha}_{i_1} \otimes \dots \otimes {\alpha}_{i_l}).$$ ]{} The proposition follows in a straightforward way from the formulae for $d^k(f \circ g)_n$ in terms of the differentials of $f_n$ and $g_n$. Indeed we have $$(k!)^{-1} d^k(f \circ g)_n = \sum_{\substack{1 \le l \le k \\ i_1 + \dots + i_l = k \\ i_j \ge 1}} (l!i_1!\dots i_l!)^{-1} d^lf_n \circ (d^{i_1}g_n \otimes \dots \otimes d^{i_l}g_n)$$ when applied to $n$ copies of $${\beta}= \sum_{1 \le i, j \le n} e_{ij} \otimes b_{ij}$$ the left-hand side gives $$\sum_{1 \le p_1,\dots,p_{k+1} \le n} e_{p_1p_{k+1}} \otimes {\gamma}_k(b_{p_1p_2} \otimes \dots \otimes b_{p_kp_{k+1}})$$ while the right-hand side is $$\sum_{1 \le p_1,\dots,p_k \le n} e_{p_1p_{k+1}} \otimes S_{p_1\dots p_{k+1}}$$ where $$\begin{aligned} S_{p_1\dots p_{k+1}} = &\sum_{\substack{1 \le l \le k \\ i_1 + \dots + i_l = k \\ i_j \ge 1}} {\beta}_l({\alpha}_{i_1}(b_{p_1p_2} \otimes \dots \otimes b_{p_{i_1}p_{i_1+1}}) \cdots \\ &\otimes {\alpha}_{i_l}(b_{p_{i_1+\dots+i_{l-1}+1},p_{i_1+\dots+i_{l-1}+2}} \otimes \dots \otimes b_{p_{i_1+\dots+i_l},p_{i_1+\dots+i_l+1}})).\end{aligned}$$ Comparing the two proves the proposition. The Asymptotic Integral Formula for the Coefficients in the Unit Disk when $B = {{\mathfrak M}}_k$ {#sec14} ================================================================================================== {#sec14.1} We will build on the series expansion results to study stably matricial analytic functions in the unit disk. We will prove stably matricial analogues of the classical facts about density of polynomials and about the identification of the coefficients with the Fourier coefficients of the restriction to the unit circle. Here the role of the unit circle will be taken by the stably matricial unitary group ${{\mathcal U}}(B)$. Integration on ${{\mathcal U}}(B)$ will be the large $N$ limit of integrations with respect to Haar measures. [We will assume that $B = {{\mathfrak M}}_k({{\mathbb C}})$ in [\[sec14.3\]]{} and [\[sec14.4\]]{}. The case $B = {{\mathbb C}}^k$ will be the subject of section]{} \[sec16\]. Polynomial approximation for totally bounded analytic functions {#sec14.2} --------------------------------------------------------------- [Definition.]{} A $B_2$-valued stably matricial function $f$ on the stably matricial $B_1$-set $\Xi$, where $B_k$ are $C^$-algebras is [totally bounded]{} if for some $t > 0$, $tf$ factors through the inclusion ${{\mathcal D}}_0^{cl}(B_2) \subset {{\mathfrak M}}(B_2)$. We define the uniform norm $\\|f\\|_{{\infty},\Xi}$ of $f$ to be the infimum of the $t^{-1}$ or equivalently to be $$\sup_{n \in {{\mathbb N}}} \sup_{{\beta}\in \Xi_n} \\|f_n({\beta})\\|$$ where ${{\mathfrak M}}_n(B_2)$ is endowed with the $C^$-norm. If $\Xi = R{{\mathcal D}}_0(B_1)$ we shall also write $\\|f\\|_{{\infty},R}$ for $\\|f\\|_{{\infty},\Xi}$. If $\Xi$ is an open stably matricial set, we shall put $${{\mathbb H}}^{{\infty}}(\Xi) = \{f \in {{\mathcal A}}(\Xi) \mid \\|f\\|_{{\infty},\Xi} < {\infty}\}.$$ [Proposition.]{} [ If $B$ is a finite-dimensional $C^$-algebra and $f \in {{\mathbb H}}^{{\infty}}(R'{{\mathcal D}}_0(B))$ then given $0 < R < R'$ and ${\varepsilon}> 0$, there is $Z \in {{\mathcal Z}}(B^d)$ so that $$\\|f-Z\\|_{{\infty},R} < {\varepsilon}.$$* ]{} [*[Proof.]{}]{} If $g: \{z \in {{\mathbb C}}\mid \|z\| < R'\} \to {{\mathcal X}}$, where ${{\mathcal X}}$ is a Banach space, is an analytic function and if $\sup_{\|z\| < R'} \\|g(z)\\| = M$ then we have the well-known bound $$\sup_{\|z\| \le R} \left\\| g(z) - \sum_{0 \le n < N} c_nz^n\right\\| \le M(R/R')^N(1-R/R')^{-1}$$ where $\sum_{n \ge 0} c_nz^n$ is the series expansion of $g$ at zero. Since the series expansion at the origin of $f_n$ restricted to any one-dimensional subspace of ${{\mathfrak M}}_n(B)$ is the series expansion of the restriction of $f_n$ to that subspace, we infer that if ${\beta}\in {{\mathfrak M}}_n(B)$, $\\|{\beta}\\| \le R$ then $$\begin{aligned} &\left\\|f_n({\beta}) - f_1(0)I_n - \sum_{1 \le k < N} (k!)^{-1}d^kf_n(0_n)[{\beta},\dots,{\beta}]\right\\| \\ &\le C(R/R')^N(1-R/R')^{-1}\end{aligned}$$ where $C$ is the uniform norm of $f$ on $R'{{\mathcal D}}_0(B)$. By Theorem \[sec13.8\] and Remark \[sec13.8\] this means that $$\\|f-Z\\|_{{\infty},R} \le C(R/R')^N(1-R/R')^{-1}$$ for a polynomial function $Z \in {{\mathbb Z}}(B^d)$. Choosing $N$ large enough the right-hand side will be $< {\varepsilon}$. The asymptotic integral formula for the coefficients {#sec14.3} ---------------------------------------------------- We precede the proof of the integral formula by some free probability preparations. [Lemma.]{} [ Let $(A,{\varphi})$ be a noncommutative probability space and let $U \in A$ be an invertible element and let $1 \in M \subset A$ be a subalgebra of $A$, so that $M$ and $\{U,

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his wicket-taking spells will be desperate to regain that momentum before the tour of Australia and could have a say in the third T20. 3. Dinesh Karthik - Batsman, India Dinesh Karthik is always comfortable playing in Chennai before his home crowd. And with a possible captaincy role in the third T20, Karthik will be keen to have some kind of an impact in the match. He is also the preferred wicket-keeper over Rishabh Pant and could get you a lot of points through his dismissals. 4. Carlos Brathwaite - Allrounder, West Indies West Indies has been completely outclassed in the last two matches and never looked like they were going to trouble the hosts. While many of the players looked tired, captain Brathwaite was the only player capable of creating something in the match. Brathwaite has been active and has shown glimpses of what he's capable of in his bowling as well as batting. With India already clinching the series, West Indies will be playing with nothing to lose and could hope for a better display in Chennai. 5. Oshane Thomas - Bowler, India With the likes of Rohit Sharma tearing through the opposition bowling attack, West Indies' bowlers have cut a disappointing figure so far in the series. But if there is anyone who could look to have an impact, it is Oshane Thomas. He was impressive in his spell in the first T20 and was the pick among the bowlers in the second T20 as well. Pick him and you could get some unexpected points should West Indies do well in the third T20 in Chennai.「大阪市を解体し、5つの特別区を設置する」ことをめぐり、5月17日に住民投票が予定されています。二期目の世田谷区長選挙を終えた私に対しても、この「大阪都構想・住民投票」をめぐり、関西のメディアからいくつか取材が重なりました。大阪都構想が、東京都と特別区の関係をモデルとしてつくられたと言われている以上は、都内最大の特別区である世田谷区を預かる立場から、特別区制度の置かれている現状について、しっかり伝えていく必要があると思っています。関東にいると、大阪都構想の詳細な部分はあまり伝わってきません。大阪都構想には変遷があり、現在の焦点となっている住民投票は、冒頭に書いたように大阪府（880万人）の中で、大阪市（270万人）のみを対象として、「政令指定都市である大阪市から５つの特別区」に移行することを問うものです。東京の特別区（907万人）は、東京都（1335万人）の約７割をしめているのに対して、大阪市の人口規模は、大阪府全体の約３割という点にも留意したいと思います。東京都は、戦時下の1943年（昭和18年）に、東京府と東京市を廃止して出来ました。東京市はなくなり、特別区が生まれてから70数年になります。区部は都に対して、粘り強く自治権拡充の運動を重ねてきました。1952年（昭和27年）には区は都の内部団体とされ、区長公選も廃止されています。区長公選を再実施するまでには、1975年（昭和50年）まで待たなければなりませんでした。特別区の自治は、長い運動の歴史によってつくりあげられ、まだ途上にあります。世田谷区は人口88万人と、7つの県（佐賀・島根・鳥取・徳島・高知・福井・山梨）を上まわる人口規模を持っていますが、首長の権限は一般の市町村長以下と聞くと、まさかと思う人も多いかもしれません。まず、税収が限られています。法人住民税、固定資産税（個人・法人）等は、都が徴収します。その55％が区に配分される「財政調整制度」で運営されています。（今回、大阪で5つの特別区をつくった場合には、配分率を77％にするとしています）財源を握っている都の立場は強くなり、配分を受ける区は「さじ加減」に財政上の大きな影響を受けます。今年、30年がかりの再開発が完成して、二子玉川に楽天本社が移転してきますが、都が法人住民税を受け、区には直接の税収はありません。間接的には、住民増で税収があがる等のメリットと、ただでさえ足りない保育需要が上昇する等の仕事を抱えることになります。一方で地方分権の流れで、都市計画決定権限が市町村に移行しましたが、「特別区」だけはまちづくりに重要な「用途地域」等を決める権限が除外されています。例えば、文化・芸術のインフラとして、ライブハウスや小劇場がつらなるまちづくりを誘導しようとしても、「用途地域」の変更なしには進められないのが現状です。ソウルでは、テハンノ（大学路）には小劇場が密集していますが、小劇場を持つビルオーナーに対して、固定資産税の減免を行なっています。世田谷区には、その権限はなく、固定資産税の減免という切り札を区の政策で使うことは出来ません。世田谷区独自の取り組みとして、出産直後の母子をケアする産後ケアセンター（桜新町）があります。全国的な反響を呼び、国の成長戦略のモデル事業とまで紹介されながら、区内で第２、第３の設置をすることが出来ません。これも、建築基準法で用途地域が制限されていることが、大きな理由です。区民の需要が高く、内外の評判が良くても、桜新町が準工業地域だったことで例外的に立地可能になったことを知る人は多くありません。人口88万都市に、まちづくりの骨格となる用途地域等の決定権限がないことは、大きな制約を生んでいます。大阪市には現在24カ所の行政区があります。住民投票では、これを5つの特別区に統合し大阪市

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sim$0.69$M_{\odot}$, and decreases to $\sim$0.63$M_{\odot}$ for $Y$=0.286. The average mass along the synthetic HB is equal to 0.66$M_{\odot}$, with a 1$\sigma$ dispersion of 0.017$M_{\odot}$. The exact values of these two quantities depend on the assumed distribution of initial $Y$, but obviously the mean mass cannot be outside the range 0.63-0.69$M_{\odot}$. A general trend of increasing $Y$ with decreasing colour is also fully consistent with the observed trend of increasing Na towards bluer colours along the cluster HB [see @gratton]. We could have tried to enforce [*a priori*]{} the constraint of perfect statistical agreement between the theoretical and observed star counts. However, a perfect fit rests on the precise knowledge of the statistical distribution of $\Delta M_{\rm RGB}$ and the initial $Y$ among the cluster stars. Due to the current lack of firm theoretical and empirical guidance, this distribution may be extremely complicated and/or discontinuous. The constraints imposed on the matching synthetic HB are however sufficient to put strong constraints on $\Delta M_{\rm RGB}$ –the main parameter discussed in this work– and the range of initial $Y$, which determine the region of the CMD covered by the observed HB. In fact, just the observed shape of the HB allows a good determination of both $\Delta M_{\rm RGB}$ and the $Y$ range, when $E(B-V)$, age and initial chemical composition are fixed, as can already be inferred from Fig. \[HBtracks\]. More in detail, Fig. \[HBvariations\] shows how changing these two parameters affects the shape and location of the synthetic HB. Variations of $\Delta M_{\rm RGB}$ around the reference value –keeping the reference $Y$ distribution fixed– move the location of the synthetic HB along the direction from the top-right corner of the CMD to the bottom-left one. At the same time the HB gets compressed when $\Delta M_{\rm RGB}$ is reduced (shorter loops in the CMD of the HB tracks of larger mass) and stretched when $\Delta M_{\rm RGB}$ is increased. No change of the cluster distance modulus can bring into agreement any of these two synthetic CMDs with the observed HB. Variations of $\Delta Y$ –keeping the reference $\Delta M_{\rm RGB}$ unchanged– stretch or compress the synthetic HB along the direction from the top-left corner of the CMD to the bottom-right one. Also in this case, variations of the cluster distance modulus do not compensate for the change of $Y$ distribution. ![Distribution of stellar mass (top panel) and initial $Y$ values (bottom panel) as a function of the colour $(B-V)$, for the stars in the synthetic CMD displayed in Fig. \[HBref\].[]{data-label="HBrefdistr"}](figpapHB47tuc_4.eps){width="\columnwidth"} A decrease of $\Delta Y$ to 0.025 and variations of $\Delta M_{\rm RGB}$ within less than 0.01 $M_{\odot}$ do still allow a satisfactory fit to the observed HB, according to the criteria described above, but larger variations are clearly ruled out because the resulting synthetic HB would clearly have a different shape than observed. Values of $\Delta M_{\rm RGB}$ below 0.20$M_{\odot}$ are totally incompatible with the observed HB morphology and location in the CMD. We have also experimented with a mass loss linearly dependent on the initial $Y$ distribution. Considering $\Delta M_{\rm RGB}$=0.23$M_{\odot}$ for the population with $Y_{\rm min}$, a synthetic HB with $\Delta Y$=0.03 and $\Delta M_{\rm RGB}$ increasing at most as 0.5 $\times$ $\Delta Y$ provides a fit to the observations of comparable quality as the baseline simulation. This implies $\Delta M_{\rm RGB}$ higher by just 0.015$M_{\odot}$ for the most He-rich component. Experiments with $\Delta M_{\rm RGB}$ decreasing with $Y$ show that at most $\Delta M_{\rm RGB}$ can decrease as 0.15 $\times$ $\Delta Y$, implying a negligible decrease of the RGB mass loss as a function of $Y$. ![As Fig. \[HBref\], but for the labelled values of $\Delta M_{\rm RGB}$ and $\Delta Y$ (see text for details)[]{data-label="HBvariations"}](figpapHB47tuc_5.eps){width="\columnwidth"} As an additional test we have calculated a synthetic HB by considering the reference $\Delta M_{\rm RGB}$=0.230$\pm$0.005 (Gaussian spread) for all $Y$, but with a different distribution of initial He abundances. We have considered in this case 70% of the stars with a Gaussian distribution of initial $Y$ characterized by mean value $<Y>$=0.275 and spread $\sigma(Y)$=0.007, and the remaining 30% with a very narrow Gaussian distribution with $<Y>$=0.258 and spread $\sigma(Y)$=0.0008. This choice stems from the results by @milonetuc, who found a bimodal MS for this cluster, corresponding to $\sim$0.02 difference in initial $Y$. The adopted distribution in our simulations has a difference of $\sim$0.02 between the mean values of the two Gaussians, and a total range $\Delta Y$=0.03, that is needed to cover completely the $V-(B-V)$ region occupied by observed HB. The 70/30 ratio comes again from @milonetuc analysis of the number ratio between the two populations of different initial He as a function of the distance from the cluster centre. For the same distance modulus of our reference simulation, mean $V$ and mean $(B-V)$ of the observed HB are again matched within 0.01 mag, although star counts as a function of colour and magnitude are slightly less well reproduced. The main point of this simulation is that a change of the initial $Y$ distribution of the HB stars does not affect the $\Delta M_{\rm RGB}$ required to match the CMD location of the observed HB. Analysis of the uncertainties ============================= In the previous section we have found that for the adopted reference \[Fe/H\]=$-$0.7, \[$\alpha$/Fe\]=0.4, $E(B-V)$=0.024, t=11.5 Gyr, our synthetic HB simulations require that RGB stars lose $\Delta M_{\rm RGB}$=0.23 $M_{\odot}$ (and have a range of initial He abundances $\Delta Y$=0.03) to match the observed location and morphology of the HB, corresponding to stellar masses in the range 0.63-0.69$M_{\odot}$. This value of $\Delta M_{\rm RGB}$ (and $\Delta Y$) is broadly in line with previous results based on synthetic HB modeling [@dicri; @gratton], but in total disagreement with the conclusions by @heyl_b about RGB mass loss, based on cluster dynamics. @heyl_b results specifically exclude HB masses of the order of 0.65$M_{\odot}$. In the following we will discuss quantitatively how our reference estimate of $\Delta M_{\rm RGB}$ may be affected by a series of observational and theoretical uncertainties. Cluster reddening, age and chemical composition ----------------------------------------------- The first obvious source of systematics is related to the range of reddening, chemical composition and age estimates found in the literature. We analyzed these effects by varying one parameter at a time. In all these cases the value of $\Delta Y$ required to reproduce the observations is unchanged compared to the baseline case. Increasing $E(B-V)$ (our baseline simulation has employed the lowest estimate of the cluster reddening) tends to increase $\Delta M_{\rm RGB}$. For example, assuming the widely employed value $E(B-V)$=0.04, we obtain $\Delta M_{\rm RGB}$=0.24$M_{\odot}$, whilst for the upper limit $E(B-V)$=0.055 we obtain $\Delta M_{\rm RGB}$=0.26$M_{\odot}$, e.g. we need lower masses to match the observed HB. As already mentioned, @mmc determined star-to-star variations around the mean reddening by at most $-$0.007 mag and +0.009 mag, respectively, with mean variations smaller than these extreme values. This amount of differential reddening will hardly affect the value of $\Delta M_{\rm RGB}$, as detailed below. Let’s assume –to maximize this effect– that the stars at the red edge of the observed HB have all a reddening 0.007 mag lower than the mean value. To compare with theory, their colours should then be increased by 0.007 mag (and their $V$ magnitudes increased by $\sim$0.02 mag) to reduce the observed HB to a single value of $E(B-V)$, causing a decrease of $\Delta M_{\rm RGB}$ by just $\sim$0.01$M_{\odot}$ in this extreme case. At the same time, assuming all stars along the blue edge of the [*wedge*]{} have a reddening 0.009 mag higher than the mean value, their colours should be decreased by the same amount and their $V$ magnitudes also decreased by $\sim$0.03 mag. This would require a negligible increase of $\Delta Y$, and $\Delta M_{\rm RGB}$ increasing with $Y$ as 0.

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interesting to note that in its initial suit against the insurance company, one of the issues was whether the plaintiff also had to be discharged from his reserve status in the Guard to qualify him to collect the benefits. It appears that only after this became apparent to the plaintiff under the provisions of the policy that litigation was commenced against Cole, Hamilton and Sandell alleging a conspiracy to defraud 14 In his brief, Sandell also asserts that the military non-reviewability doctrine limits a court's review of the established relationship between enlisted military personnel and their superior officers. Chappell v. Wallace, 462 U.S. 296, 103 S.Ct. 2362, 76 L.Ed.2d 586 (1983). We decline to consider defendant Sandell's military non-reviewability argument as we find that the evidence is insufficient to support a conspiracy to defraud claim Microelectronic devices are often manufactured in and on silicon wafers and on other types other substrates. Such integrated circuits may include millions of transistors, such as metal oxide semiconductor (MOS) field effect transistors, as are well known in the art. MOS transistors typically comprise source, drain and gate regions, in which the gate material may typically comprise polysilicon. Polysilicon gates, however, can be susceptible to depletion effects, wherein an electric field applied to a polysilicon gate sweeps away carriers (holes in a p-type doped polysilicon, or electrons in an n-type doped polysilicon) so as to create a depletion of carriers in the area of the polysilicon gate near an underlying gate dielectric of the transistor. The depletion effect can add to the overall gate dielectric thickness in the MOS device. Recently, silicon germanium source and drain regions have been incorporated within transistors utilizing polysilicon gates, which greatly improves the performance of such transistors since the strained lattice of the silicon germanium regions enhance the electron and hole mobility within the channel of such a transistor, as is well known in the art. Metal gates, on the other hand, are not as susceptible to depletion effects as gates comprising polysilicon. Typical prior art microelectronic processes, however, do not incorporate both metal gates and polysilicon gates within the same device or integrated circuit. This is due, in part, to the complexity and cost of developing a microelectronic process that can reliably form both a metal gate structure and a polysilicon gate structure within the same microelectronic device or integrated circuit. It would therefore be advantageous to incorporate both a metal gate structure and a polysilicon gate structure with silicon germanium source and drain regions. The methods and structures of the present invention provide such a process.If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. i say conspiracy theory. the nfl is making sure the refs give the steelers enough leeway til big ben is healthy. the steelers are one of the afc's darling teams and it makes more sense for a team pushing for that wildcard birth to lose to give pitt some breathing room :-) theres ya another conspiracy. we'll play it out through the weekend. but yeah we played like doo doo on offense, refs have nothing to do with that. we couldnt block, we couldnt run, we couldnt move it through the air. but we were deflated early i think, which sucks because a team with veteran pressence shouldnt allow that to happen. the running into kicker was hit or miss, some games its called, others its not. ive seen blocked into kicker before and this is one that i prob would've called. but on the return you saw one of the bills players have his hands on a fins back and then he throws up his arms, they wouldnt show it on replays. ive said that i thought the 2nd PI call and the holding call on carroll were garbage, eeven the announcers said the holding call was garbage and they were pro buffalo the entire game. hartlines fumble i would say most refs would reverse the call and say incomplete pass, if they wouldve called the PI on hartline on the deep route it would've been huge. that is one that the WR gets most of the time on field. once again i think the pro-buf announcers even said hartlines offense-PI shouldnt been called. wake had to be reaching for an inhaler after the game cause he had arms around his neck as we was running by tackle so many times while being held. granted the refs did not stop our running game, we didnt block. they didnt stop our passing game (other than some bad calls), or our bad play calling. Good teams win inspite of adversary, we didnt, we're not a good team, yes i think we've lost a couple games this year cause of officiating, but if we were truly a good team the officiating wouldnt even matter. i just want to see us winning again, back when we were the leagues "darlings" the calls went our ways like it, believe it, or not. we become good again we'll get these calls, but right now they have to take care of their money makers, ala Pitt and Ind, and the best way to do that is by putting distance so "scrubs" like the fins dont make it in. Fins Up! 10-6 :-) I realize we played badly, but I was at the game with a Green Bay fan (completely neutral), and he pointed out several OUTRAGEOUS calls. The refs really are screwing us, it is not an excuse, it is a FACT. That being said, my friend was also able to call which plays the Dolphins would run on offense about 75% of the time. Our offense is painfully predictable. I swear i saw Sparano in a Fins uniform fist-pumping on the sidelines. If the refs were out to give the Fins a "screw job", I don't think they would have flagged the Bills nearly double what they gave the Fins. That being said, I think that the officiating needs improvement. Too many terrible calls this year league wide. Originally Posted by nyjunc The Giants absolutely win it all w/ Sanchez and they probably have more playoff wins and playoff apps if Sanchez is their QB, we probably don't even make a title game w/ Eli the last 2 years........ If the refs were out to give the Fins a "screw job", I don't think they would have flagged the Bills nearly double what they gave the Fins. That being said, I think that the officiating needs improvement. Too many terrible calls this year league wide. Again, the Bills were correctly called for obvious encroachment (neutral zone infractions), offsides, and face mask penalties (got away with one too). Those calls had no real impact on the game. Unjustly, the refs gifted the Bills major field position and kept drives going which in turn limited our time of possession, time and time again. Again, the Bills were correctly called for obvious encroachment (neutral zone infractions), offsides, and face mask penalties (got away with one too). Those calls had no real impact on the game. Unjustly, the refs gifted the Bills major field position and kept drives going which in turn limited our time of possession, time and time again. Whether your statement is true or not, it fails to elude to your "screw job" theory. Were there terrible calls and non-calls against the Fins? Perhaps. I'll chalk those up to poor officiating, not malevolent officiating.A bodybuilder, who gorged on junk food and drank eight cans of energy drink to gain weight, died of liver cancer caused by years of steroid abuse. Fitness enthusiast Dean Wharmby, 39, from Rochdale, died in July after a five and a half year long battle with with his illness. Obsessed with gaining size, to obtain the perfect bodybuilder's physique, he survived on a 10,000 calorie a day diet of burgers, pizzas and bacon sandwiches - washed down with seven to eight cans of energy drink. Scroll down for video Peak of his powers: Dean Wharmby, pictured, when on steroids and at the top of his bodybuilding game Final days: Mr Wharmby, pictured with partner Charlotte Rigby, in bed towards the end of his battle with cancer The dad of one also took anabolic steroids to boost his energy and sculpt his muscles - something coroner Lisa Hashmi said was a 'direct cause' of his death. At his inquest Mrs Hashmi said Mr Wharmby's death should serve as a reminder to people of the dangerous of using steroids. She said: 'I find on the balance of probabilities that in such a fit, health-conscious young man the most probable cause of his liver tumours was the misuse of anabolic steroids. 'To my mind, there is a direct, causal link with Dean's death. 'Dean's death and the precious loss of such a young life in such circumstances ought to send out a very clear message to all those involved in the body building and fitness industries. 'Use of anabolic steroids, which is apparently rife throughout, is not without inherent risk. 'I would urge all those using and abusing such drugs to reconsider their position and ask whether it is really worth it given the life-threatening risks.'

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ausas», o «despedido» de su Fundamento. Tal _existencia_ es previa y antecedente a toda reflexión relativa a su _esencia_ o _quididad_, a _lo que es (Wassein)_. Tal existencia es «ser ahí», _Dassein_, eso _que es (quod est)_ previo a su contenido eidético establecido por la reflexión. Ese existir preexiste a cuanto la razón pueda determinar. Da fundamento en general a esas determinaciones reflexivas de la razón. Pero ésta, en su autorreflexión, no puede crearlo ni producirlo (como creyó, por última vez, Hegel en su _Gran Lógica_, particularmente en su _Doctrina de la Esencia_ ). El Fundamento que la _reflexión_ siempre _presu-pone_ no puede ser establecido o _puesto_ (en forma de _positum_, o _tesis_, que el propio proceso de autorreflexión genera). Tal _positum_ fundamental se adelanta a toda reflexión; expide o expele el _existir_ ; y religa necesariamente toda razón o reflexión a ese existir. Y el existir se hace presente y manifiesto a través de la _revelación_ : una revelación que tiene su primera presencia en el mundo de la naturaleza; y la segunda en el ámbito _simbólico_ cuya exégesis primera y natural lo constituye la gran trama de las _mitologías_. Sobre esa doble revelación, primero natural, luego mítica, puede al fin promoverse la Revelación religiosa _kath' exogen_, que es para Schelling la revelación cristiana: la doctrina trinitaria de las Tres Potencias, y la concepción de la encarnación del _lógos_ ; pero sobre todo la apertura de un horizonte _espiritual_ como culminación de la revelación. Y la filosofía, si quiere realmente hallar al fin una fundamentación _positiva_, debe dialogar con esa triple revelación (natural, mítica, cristiana) con el fin de realizar su intención de constituir un Sistema orgánico y vivo emanado de un auténtico Fundamento _positivo_. De este modo Schelling intenta articular y conjugar, en una verdadera _síntesis espiritual_, una _filosofía positiva_ que se despliega como filosofía de la revelación, que tiene el primer peldaño en la filosofía de la naturaleza y el segundo en la filosofía de la mitología, y una _filosofía negativa_ que pretende, según presupuestos idealistas y sistemáticos (siguiendo la tradición cartesiana, kantiana, o incluso hegeliana), incoar un proceso de autoproducción que sea, a la vez, una genuina autofundamentación. Sólo que esta última debe siempre presuponer el _positum_ de aquel Fundamento originario y matricial, verdadero Abismo, _Ungrund_, del cual sale despedida la _ex-sistencia_ (eso _que es_ fuera de su Causa). Y esa existencia, que al ser despedida da lugar a su propia _revelación_, no puede ser deducida por la _filosofía negativa_ : no puede inferirse del «movimiento esencial», o movimiento de autorreflexión, tal como pretende Hegel en su _Doctrina de la Esencia_, en su _Lógica Mayor_. Schelling, pues, apunta a una _conmodulatio_, o _armonía oppositorum_, entre esas dos grandes ramas del mismo tronco filosófico: la tradición de una «reflexión» filosófica que, al modo de la antigua y medieval, presuponga siempre el _dato_ positivo (previamente implantado, «puesto») de una _revelación_ que se produce en clave _simbólica_ (y cuya exégesis corre a cargo de la mitología y de la religión revelada); y la tradición de la modernidad cartesiano-kantiana, seguida por el propio Schelling y por Hegel, según los postulados metódicos y críticos del idealismo alemán, con su voluntad sistemática por autoengendrar en y desde la propia reflexión racional todo el conjunto de lo existente, de manera que el proceso de gestación de realidad coincida con el propio proceso de auto-fundamentación del pensamiento. Schelling apunta con todo ello hacia el horizonte de un posible nuevo eón en el cual tal conjunción copulativa entre revelación simbólico-religiosa y reflexión racional pudiera consumarse: la expectativa misma relativa al último de los eones de este ciclo espiritual. Pero esa expectativa de Schelling termina en un «acorde de séptima». La síntesis de filosofía positiva y de filosofía negativa no llega a producirse. Schelling muere sin hallar el broche áureo que sellara los dos lados de una realidad espiritual escindida. En lugar de eso Schelling pone punto final a este eón idealista y romántico abriendo el largo y tortuoso curso del régimen de experiencia y reflexión del mundo contemporáneo, que parece instalarse justamente en esa fisura abierta. En ese mundo que se inicia en la década de los cuarenta del siglo XIX la escisión entre el _factum_ positivo al que debe recurrir toda reflexión y ésta parece ahondarse hasta el paroxismo. Se inicia así el régimen de una _cesura dia-bálica_ que domina de modo hegemónico desde entonces hasta nuestro presente histórico. Todo el pensamiento contemporáneo tiende a instalarse en esa cesura, rehuyendo siempre todo intento por suturarla mediante una genuina síntesis espiritual. De hecho, se retiene de la filosofía del último Schelling la premisa de que la reflexión debe ser antecedida por una _base real y material_ que no puede ser autofundamentada por la Razón. Sólo que ese Fundamento pierde entonces el halo místico y sagrado que conservaba en la filosofía de Schelling, regiamente instalada en el eón místico y romántico. No es ya ese _Grund-Ungrund_, o fundamento abismal, que Schelling había recreado a partir de la inspiración que le proporcionaba el _Mysterium Magnum_ de Jakob Böhme, su libro de cabecera. Este recurso a fuentes esotéricas (teosofía mística de Böhme, tradiciones cabalistas) característico del último Schelling deja paso a una interpretación _desmitificadora_ de la «base material», del fundamento natural y físico, o de la idea de Fundamento. Tal es el paso que dan, en este punto, los seguidores de la crítica de Schelling al idealismo absoluto de Hegel: Feuerbach, Marx, Engels, Bakunin, el propio Kierkegaard. El _hiato_ entre razón y revelación, o entre el fundamento _real_ y la reflexión filosófica promueve una constante basculación entre una interpretación _positivista_ del _positum_ (que será para Feuerbach la naturaleza material, y para Marx y Engels el mundo material-social de la economía política) y una interpretación radicalmente crítica respecto a todas las pretensiones de la Razón por suturar ese _hiato_ (así Kierkegaard). Entre un racionalismo positivista desengañado de toda embriaguez mística y romántica, y un evidente «irracionalismo» que no quiere ya negociar con ningún atisbo de racionalidad (en relación a los negocios supremos de la existencia, la fe, la salvación, etcétera), se abre un auténtico abismo por el cual circula, en plena crisis, la gran _cesura dia

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should make that more precise: with-syntax-table temporarily alters the current syntax table of whichever buffer is current at the time the macro execution starts. Other buffers are not affected.Tag: Hope One of the most difficult questions I’ve had to answer after our family’s 3-week vacation to the States was “How was your trip?”. Every single time a friend or a colleague asked me this, I took a deep breath, smiled, and said: “It was good! Really fun!” But, behind those answers was a heart breaking inside of me. Yes, by God’s grace, there were good and amazing highlights which I hope to share sometime soon. However, I couldn’t just let go of the fact that our family went through an emotional roller coaster ride that continued even a month after we got back to the Philippines. We went home to the same house each day and had occasional chats, but there was definitely an elephant in the room. PRIDE IN THE FAMILY The trip was supposed to be a fun time with the family because of three main reasons: 1) Our eldest sister’s wedding and meeting the extended family in Hawaii, 2) Our family reunion with my father’s side, and 3) Our whole family’s first time to travel the States together. But while we were still in the States, our different types of personalities clashed almost every day. From the smallest concerns to the biggest problems we encountered, the pride in us took over our hearts and minds. Unfortunately, this caused us to stumble and sin not only in our thoughts, but also in the harsh and unloving words that we carelessly threw against each other. When someone made a mistake, some of us were quick to judge and comment about it. When someone made suggestions, some of us chose to disregard and belittle them. When someone opened up that he/she was hurt, the other side became defensive. When we experienced delays, hassles, or detours during the trip, blaming and getting annoyed at each other became a normal response. Moreover, smiling for the camera in between these moments was the cherry on top! It was very tiring and frustrating. INDIFFERENCE IN THE FAMILY As each day passed by, I kept telling God about my disappointment and heartbreak because of our family’s situation. There were moments when I would cry or cringe especially when I would see myself and my other family members being joyful with others, yet having not much emotion or interest back at home. It broke my heart to see how it was normal for us to worship God and serve others when we ourselves weren’t honoring God in our relationships in the family. I also noticed that some of us preferred staying out late instead of going home early to spend more time with the family. In addition, some of us kept ourselves busy with work or other interests, since it was more convenient compared to dealing with the problem. In a nutshell, our family was already giving up on each other. “Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God. – Psalm 43:5 HUMILITY IN THE FAMILY Last Saturday, during a road trip with my older sister to a coffee farm, I had the opportunity to open up to her and share what I was feeling and thinking of, in relation to the elephant in the room. I said things like: “I honestly don’t know my parents and siblings anymore. We don’t make time for each other which causes us to be quick in judging and not understanding each other.” and “I’ve been ranting about this to God almost every day. I feel like He’s telling me to stop ranting and to start doing something about it!” Our exchanges of experiences led us to agreeing that we needed to resolve issues and have a family meeting. We just couldn’t imagine seeing this problem snowball into something bigger in the years to come. I sent out a chat invite to our family’s group chat and surprisingly, they all (parents, older sister, and younger brother) confirmed their attendance for the next day. Ironically, that same road trip, I let my pride take control of me and it caused a tension between me and my sister (which I shared in my previous POST). But, God used that experience for me to understand the value and blessing of humility and by His grace, this inspired me to be intentional in praying for and facilitating our family meeting that weekend. It was one of the awkward moments I’ve had with the family. Seeing them walk in the coffee shop one by one and knowing that we all had unresolved issues in our hearts. But somehow, God was encouraging me to trust that He is more than able to restore our relationships in His perfect timing. After Mom opened in prayer, I started to lead the discussion by sharing that the purpose of our talk that night was for us to be aware of the situation we had and to trust that God will help us restore what was broken. I then asked everyone (including myself) two questions that night. The first question was: “What changes do you desire to see in our family?”. This was our chance to let each other know about the improvements that we wanted to see in the members of the family. After around 10 minutes, I asked them the second question: “What changes do you desire to see in YOURSELF, in relation to the family?”. I remember seeing some of their eyes widen and hearing some say “ohh my!”. I guess it was a question that they did not expect. After everyone finished typing their answers on their mobile phones, I said: “Okay! It’s now time to share our answers to the group. Let’s begin with question… #2.” By God’s grace, He inspired me to set the tone of humility in our discussion by starting with the second question. Knowing our family (based on the previous open forums we’ve had in the past years), whenever we first shared about family issues and problems because of each other, our conversations did end up having action steps, but they also turned a bit sour afterwards. Sometimes, there would still be conversations after the open forum where some of us would say, “I still felt that I wasn’t understood when I opened up…” and all those similar responses. So, for our recent family meeting, it was refreshing and very humbling for each of us to start the discussion by admitting our own weaknesses, shortcomings, and desires to improve ourselves within the context of family. By the time we moved on to question #1, the issues and concerns shared were willingly welcomed by each member. After a loooong time, I sincerely saw how each member was intentional in hearing out and understanding where the hurting member was coming from. There were no defensive or harsh comments made and when we were almost leaning towards a tension, the other members helped in balancing the conversation. Not only did we get to know each other and our hurts more, we also had the opportunity to forgive, to ask for forgiveness, and to believe in the best towards each other. Hugs were given, tears were shed, funny comments were occasionally said, tips to love each other were shared, and walls among us were slowly being destroyed. HOPE FOR THE FAMILY We ended the night by encouraging each other to grow in our relationship with Jesus and in our love for each other, by the power of the Holy Spirit. My heart was overjoyed, not because all of our family concerns were solved, but because we found hope in Jesus. In spite of our weaknesses, He is more than able to transform our hearts and do miracles in our families, no matter how simple or hopeless the situations and problems may be. All it takes is a step of faith when He calls us to act on it and trust in Him. You too might wonder: “Is there hope for my broken family?” I think you already know the answer to it. Will you believe it? :) “May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.” –Romans 15:13 On my way home from work last Friday night, I recorded a song in the car, out of the overflow of my heart. Just a few seconds after I said thanks to God for allowing me to finish it, I heard a loud, consistent beat at the right side of my car. A motorcyclist who drove by me then, signaled me to stop and look at my wheel. During the next three minutes, my world slowed down as I went out of the car to inspect the damage. My jaw dropped as I saw my exploded tire at the side of the passenger’s seat. My mouth blurted out, “Shocks, Lord. Is this really happening? Please help me.” Within a minute, even before I could call my dad, another motorcyclist stopped by to ask if I needed help. My initial reaction was “I hope this guy isn’t sketchy.” But in my desperation, I said, “Yes, please!” He spent the next 10 minutes, going through my car tools at the back, setting up my emergency signals, and trying to release the spare tire that was hidden under my car. I remember telling him countless times how much I appreciated his help and how it really was impossible for me to change my tire by myself. After a few minutes, another motorcyclist stopped by to offer assistance. They ended up helping each other as they raised my car, changed my tire, protect me from being scammed by tow people, and even assist me as I drove to the nearest vulcan

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In 1949, Hadassah inaugurated the Henrietta Szold prize, which was awarded that year to Eleanor Roosevelt.The Henrietta Szold Institute, National Institute for Research in the Behavioral Sciences, located in Jerusalem, is named after her. The institute is Israel's foremost planner of behavioral science intervention and training programs.Public School 134 on Manhattan's Lower East Side in New York City is also named after her.In 2007, Szold was inducted into the National Women's Hall of Fame in Seneca Falls, New York.In Israel, Mother's Day is celebrated on the day that Szold died, on the 30th of Shevat. In the northwest corner of Szold's home city of Baltimore, Szold Drive, a short street in a residential neighborhood with homes built in the 1950s, is named after her as well. The northernmost part of the street is in Baltimore County. In New York City, Szold Place, formerly Dry Dock Street runs from East 10th Street to East 12th Street in the East Village neighborhood of Manhattan. == See also == Benjamin Szold Robert Szold Zip Szold Cancer causes 8·2 million deaths each year worldwide, accounting for 13 % of all deaths. Annual numbers of new cancer cases worldwide are expected to rise by 70 % over the next two decades^(^ [@ref1] ^)^. While greater uptake of screening and increasingly effective treatments have reduced mortality rates for some cancers^(^ [@ref2] ^--^ [@ref4] ^)^, there is a growing realization that primary prevention through lifestyle and environmental interventions may offer a more sustainable solution for reducing cancer burden^(^ [@ref1] ^,^ [@ref2] ^,^ [@ref5] ^)^. Estimates for the impact of modifiable risk factors on cancer incidence vary according to the assumptions used to create the statistical models and on the source and quality of the underlying data^(^ [@ref6] ^,^ [@ref7] ^)^. However, regardless of the variation in different population-attributable fractions for each risk factor, there is a general consensus that use of tobacco, physical inactivity, low fruit and vegetable intake, high intake of red and processed meats, overweight and obesity, and use of alcohol are responsible for up to 30 % of cancer incidence overall^(^ [@ref8] ^--^ [@ref13] ^)^. In 2007, the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) produced a series of population goals and personal recommendations for cancer prevention based on these modifiable behaviours and health-related variables^(^ [@ref14] ^)^. The rationale was to provide a robust evidence base to inform the development of policies and interventions to help reduce cancer risk in the general adult population. However, before moving towards policy development, it is important to understand more about the concurrence between existing health-related variables and behaviours and current recommendations. Such information may be useful in identifying priority areas for further investigation and intervention. The aim of the current study was to explore the extent of adherence to WCRF/AICR cancer prevention recommendations for individuals^(^ [@ref14] ^)^, based on behaviours and health-related variables reported by adults enrolled in Alberta's Tomorrow Project (ATP), Alberta, Canada. A comprehensive overview of adherence to cancer prevention guidelines and the associated influential factors can inform cancer prevention strategies and assist in designing consistent targeted strategies to increase population adherence to evidence-based cancer prevention guidelines. Methods {#sec1} ======= Study population {#sec1-1} ---------------- Between 2001 and 2009, ATP enrolled 31 212 Albertans aged 35--69 years, with no personal history of cancer other than non-melanoma skin cancer, into a cohort. Participants were recruited by random digit dialling using Regional Health Authority boundaries as the sampling frame. In the first recruitment wave, a second eligible adult within each household was recruited (*n* 382, 1 %) if possible; but this practice was discontinued in subsequent recruitment waves^(^ [@ref15] ^)^. Recruits were mailed an information package and were considered enrolled if they returned a completed Health and Lifestyle Questionnaire (HLQ) and signed consent form. Three months after enrolment, participants received two additional questionnaires assessing past-year dietary habits and physical activity. Response rate to the random digit dialling call has been estimated at 32 %^(^ [@ref15] ^)^ and response rate of those individuals to enrolment was 49 %. Questionnaires {#sec1-2} -------------- The HLQ queried self-reported sociodemographic, behavioural and health-related variables including age, marital status, education, employment status, annual household income, tobacco use and exposure to second-hand smoke, family health history and body measurements (height, weight, waist and hip circumferences). In addition, participants indicated whether or not a doctor had ever told them that they had any of the following health conditions: high blood pressure, angina, high blood cholesterol, heart attack, stroke, emphysema, chronic bronchitis, diabetes, ulcerative colitis, Crohn's disease, hepatitis or liver cirrhosis. Participants who answered 'yes' to having received a diagnosis of any of these conditions were deemed to have a personal history of chronic disease. Past-year diet, including supplement use, was assessed by the US National Cancer Institute's 124-item Canadian Diet History Questionnaire I (CDHQ-I), an FFQ adapted for use in Canada^(^ [@ref16] ^,^ [@ref17] ^)^. Recent evidence supports that the food list in CDHQ-I is representative of the foods commonly consumed by Canadian adults^(^ [@ref18] ^)^. CDHQ-I data were analysed using Diet\*Calc version 1.4.3 (National Cancer Institute, Bethesda, MD, USA) to estimate mean daily intakes of nutrients and food group servings, as well as supplement use. Past-year recreational activities were assessed using a validated Past Year Total Physical Activity Questionnaire (PYTPAQ)^(^ [@ref19] ^)^. Total minutes per week performing leisure activities at moderate (3--6 MET, where MET=metabolic equivalent of task) and vigorous (\>6 MET) intensities were calculated based on reported activities. Cancer prevention recommendations adherence score {#sec1-3} ------------------------------------------------- A composite score reflecting adherence of reported behaviours and health-related variables to seven selected WCRF/AICR personal recommendations for cancer prevention was constructed for each participant using data collected upon enrolment to ATP. Recommendations included were those that addressed the general adult population and were identified as quantifiable using baseline ATP data. Recommendations addressing special groups (cancer survivors, breast-feeding women, people living in specific geographic regions) or that were not quantifiable with ATP data were excluded. It was not possible to quantify adherence to some recommendations (consume fast foods sparingly, avoid sugary drinks, limit sedentary habits), while the data required to quantify some other recommendations were not available for ATP participants (consume energy-dense foods sparingly, limit refined starchy foods, eat relatively unprocessed grains and legumes, avoid salt-preserved, salted and salty foods, do not eat mouldy cereals and pulses, avoid weight gain and increases in waist circumference throughout adulthood, ensure body weight through childhood and adolescent growth projects towards the lower end of the normal BMI range). Considering the WCRF/AICR panel emphasized the importance of tobacco exposure for cancer risk^(^ [@ref14] ^)^ in addition to the other recommendations, second-hand smoke exposure and cigarette smoking were also included in the composite score. Participants scored 1 point for each recommendation met and 0 if it was not met. Recommendations included in the current analyses were: BMI within normal range (18·5--24·9 kg/m^2^), no daily exposure to tobacco during the past year, no more than two alcoholic drinks daily for men or no more than one daily for women, consumption of five or more servings of fruit and vegetables daily, consumption of less than 500 g of red meat weekly, not taking any dietary supplements and performing at least 210 min of moderate- or vigorous-intensity recreational physical activity weekly. The composite score ranged from 0 (least adherent) to 7 (most adherent). Statistical analyses {#sec1-4} -------------------- Descriptive statistics were presented as group means and standard deviations for continuous variables and as counts and percentages for categorical variables. Multiple linear regression models were used to explore associations between participants' composite scores and potential influential characteristics. Multiple logistic regression models were used to explore the association between participants' adherence to each of the seven components of the composite score and potential influential factors. All estimation models were adjusted for age (at categorical level: 35--49, 50--59, 60--70 years), marital status (living without partner, living with partner), education level (high school or lower, college, university), employment status (not employed, retired, employed part-time, employed full-time), annual household income (\<\$CAN 70 000, ≥\$CAN 70 000), first-degree family history of cancer (no, yes), first-degree family history of chronic disease (no, yes) and personal history of chronic disease (no, yes). Analyses of the associations were reported as adjusted regression coefficients for continuous outcomes and adjusted odds ratios for binary outcomes, and corresponding 95 % confidence intervals. All analyses were stratified by sex and the criterion for statistical significance was set as *α*≤0·05 (two-tailed). All analyses were performed using the statistical software package SAS version 9.2. Results {#sec2} =======

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their picture taken as it was such a bizarre incident. North West Motorway Police tweeted: “Report of female being assaulted on M62, vehicle stopped pair of extras making to a job - posing as Zombies - takes all sorts.”Nymex not worried by screen trading glitch New York Mercantile Exchange (Nymex) said it has corrected a technical glitch that downed its electronic trading platforms last week and reassured traders that the problem was not a harbinger of doom for its side-by-side trading plan. Market participants have raised questions over the ability of Nymex's systems to cope with its forthcoming switch to side-by-side screen and pit trading (see FO Week Vol 11 No 6).Search form Your Pain Clinic Appointment You have been referred to the pain service because your pain is interfering with your quality of life and your ability to function effectively. Pain that persists can be distressing and disabling. Most of the interventions we offer will help about one third of patients and will reduce the intensity of pain but not take it away. Response to treatment varies from person to person, even if they seem to have the same symptoms. Your pain specialist will make an assessment of you and of your pain and decide which treatment(s) might be helpful in your case. Injections may help some individuals but they often only have a limited effect and should be part of a multidisciplinary (joined) management programme. A decision on an injection will only be made after a full discussion with the patient if it is considered appropriate. With support, many patients can start to exercise, engage with hobbies and resume work (full or part-time). We want to help people move forward and for this reason it is unhelpful for us to disable our patients by saying that they are unfit to work. Our Pain Clinic Service works to support you and your GP to manage your pain. The treatments we offer are familiar to your GP and your GP will be experienced in managing day-to-day queries about your pain treatment. Your pain specialist may make a pain treatment plan for you and your GP to follow together. Your GP will be able to deal with queries and if you have a problem with medication you can also discuss this with your pharmacist Treatments we offer include: Medication review TENS 1 Acupuncture course Injections as part of a multidisciplinary approach to pain management Stimulation techniques Pain Management Programme (PMP) courses are an internationally used approach to the rehabilitation of people with chronic pain conditions. They include specialist guidance about mobility and exercise, following a detailed assessment. Back Pack is group programme specifically for people with recurring episodes of back pain. Self-Management Programme (SMP). These courses are led by one of the specialist healthcare professional and a Lay Tutor, who is someone who has benefited from one of our courses as a patient and has gone on to train in the delivery of the courses. These SMP courses do not include guidance around exercise, and participants will usually have some form of exercise which they are already involved in, or which they could re-start at a low level themselves during the course. Sleep course Individuals one-to-one sessions for a particular reasons. Individual work is usually a stepping-stone towards attending a program.""" Simple script that checks if a checkpoint is corrupted with any inf/NaN values. Run like this: python inspect_checkpoint.py model.12345 """ import tensorflow as tf import sys import numpy as np if __name__ == '__main__': if len(sys.argv)!= 2: raise Exception("Usage: python inspect_checkpoint.py <file_name>\nNote: Do not include the.data.index or.meta part of the model checkpoint in file_name.") file_name = sys.argv[1] reader = tf.train.NewCheckpointReader(file_name) var_to_shape_map = reader.get_variable_to_shape_map() finite = [] all_infnan = [] some_infnan = [] for key in sorted(var_to_shape_map.keys()): tensor = reader.get_tensor(key) if np.all(np.isfinite(tensor)): finite.append(key) else: if not np.any(np.isfinite(tensor)): all_infnan.append(key) else: some_infnan.append(key) print "\nFINITE VARIABLES:" for key in finite: print key print "\nVARIABLES THAT ARE ALL INF/NAN:" for key in all_infnan: print key print "\nVARIABLES THAT CONTAIN SOME FINITE, SOME INF/NAN VALUES:" for key in some_infnan: print key print "" if not all_infnan and not some_infnan: print "CHECK PASSED: checkpoint contains no inf/NaN values" else: print "CHECK FAILED: checkpoint contains some inf/NaN values" [Stress and alcohol: research with experimental animals]. Research on the interaction of ethanol and stress with experimental animals are briefly reviewed. There might be the two aspects of the interaction of stress and ethanol, i.e., how stress affects ethanol ingestion and response to ethanol, and how ethanol modifies stress response. In general, stress increases ingestion of ethanol in animals exposed to various stresses including electric shock, immobilization and psychological or emotional stresses, wherein the psychological or emotional factors were predominantly involved. However, in most cases, ethanol ingestion is increased after release from stress not during exposure to stress. A variety of stressful stimuli caused marked increases in the neurotransmitter release in many brain regions. Immobilization stress increased noradrenaline release in the extended brain regions in rats. These increases were significantly attenuated by pretreatment with ethanol in the rat amygdala and locus coeruleus, but not in the hypothalamus, although ethanol by itself increased noradrenaline release in the hypothalamus. Further, psychological stress, wherein the rats were given no electrical shock, but exposed to the emotional responses such as struggling, vocalization, jumping and defecation shown by the other electrically-shocked rats, increased noradrenaline release preferentially in the hypothalamus, amygdala and locus coeruleus. Among the former two regions, stress-induced increases in noradrenaline release were significantly attenuated by ethanol in the amygdala, but not in the hypothalamus. Together with the finding that increases, in noradrenaline release are closely related to the provocation of anxiety and/or fear, ethanol, in part, reduced tension, as mentioned in the tension reduction hypothesis, by attenuating stress-induced increases in noradrenaline release in the amygdala and locus coeruleus. Moreover, ethanol, administered i.p. and directly through the microdialysis probe, increased dopamine release in the nucleus accumbens assessed by in vivo microdialysis, similarly as addictive drugs such as amphetamine did. This might be, in part, neurochemical basis for motivation of repeated drinking of ethanol.Q: Returning a pointer using get method from class and using *& to take it in recursively So I am just working on some code and have kind of stumped myself I have a class Node and another class BinaryTree: class Node { public: Node(); Node(int thedata, Node* right, Node* left):data(thedata), right_pointer(right), left_pointer(left){}; int get_data(){return data;} Node* get_right() {return right_pointer;} Node* get_left() {return left_pointer;} private: int data; Node* right_pointer; Node* left_pointer; }; class BinaryTree { private: Node* root; void add_tree_node(Node*& root,int data); void print_tree(Node* root); public: BinaryTree(); void print_tree(); void add_tree_node(int data); }; My issue is with this command: add_tree_node(root->get_right(), data); I get an error saying: no instance of overloaded function. which get_right() returns a pointer to the pointer and was wondering if there was a better way of doing this instead of the two options below. when I do this: Node* right = root->get_right(); add_tree_node(right, data); or add_tree_node(root->right_link,data); it works and I understand why it works because we are passing in the pointer itself and not the value. A: Node* &get_right() {return right_pointer;} Node* &get_left() {return left_pointer;} Tag Archives: personal identity Post navigation Readers of C. S. Lewis’ The Lion, The Witch, and the Wardrobe will remember the novel’s dramatic ending: Peter, Lucy, Edmund, and Susan, now all grown up and ruling as noble and just kings and queens of the land of Narnia, set out to hunt a mysterious stag; their hunt leads them into the woods, toward ‘

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time Database instances created via Firebase Console. They do have plans for adding the feature,but It'll come in the future. For now, you can watch their updates here: https://firebase.googleblog.com https://firebase.google.com/support/releases Their support suggested me to wipe all data and to lock down the database to prevent any usage, as a work-around for now. Just remembering that having multiple instance is only possible if you have a Blaze account. As the desire for enhanced communication bandwidth escalates, transmission media are pressed to convey information at higher speeds while maintaining signal fidelity and avoiding crosstalk. For example, a single communication cable may be called upon to transmit multiple communication signals over respective electrical conductors concurrently. Such a communication cable may have two or more twisted pairs of insulated electrical conductors (“twisted pairs”) that are separated by a conventional element disposed in the core of the communication cable. The conventional element attempts to maintain some level of relative positioning of the twisted pairs within the cable for addressing crosstalk, which has posed perennial design challenges for high-performance 4-pair data cables. In many circumstances, movement of twisted pairs relative to one another within conventional communication cables can lead to decreased signal performance. For example, when a conventional cable is installed, external and internal forces may reorient the twisted pairs within the cable to positions at which crosstalk may escalate and signal quality may diminish. Accordingly, what is needed is an improved capability for orienting signal conductors, electrical conductors, and/or twisted pairs within a communication cable. A need exists for a technology that can improve placement of electrical conductors within a communication cable. A need also exists for a capability to maintain relative positions of electrical conductors within a communication cable while the cable is deployed, installed, or otherwise moved, twisted, bent, and or unrolled. A further need exists for a pair positioning member that can be readily anchored within a communication cable to facilitate robust positioning. A need further exists for a pair positioning member having reduced material relative to conventional technology, to facilitate lower manufacturing and material costs, lighter weight cables, and less material to generate flames or smoke during burn tests. A capability addressing one or more such needs or some other related deficiency in the art would enhance bandwidth that a communication cable can carry reliably.--- abstract: 'For $\lambda$ an $n$-th power of a unit in a finite chain ring we prove that $\lambda$-constacyclic repeated-root codes over some finite chain rings are equivalent to cyclic codes. This allows us to simplify the structure of some constacylic codes. We also study the $\alpha +p \beta$-constacyclic codes of length $p^s$ over the Galois ring $GR(p^e,r)$.' author: - 'Aicha Batoul, Kenza Guenda and T. Aaron Gulliver [^1]' title: | Some Constacyclic Codes over\ Finite Chain Rings --- Introduction ============ Constacyclic codes are a generalization of cyclic codes. While the class of simple root constacyclic codes is well known over fields, little is known about repeated root constacyclic codes over fields, and even less about these codes over finite chain rings. Recently, simple root constacyclic codes over finite chain rings and the repeated root cyclic and negacyclic codes over finite fields have been studied [@G-G; @G-G12]. In this work, we generalize the results in [@G-G; @G-G12]. The structure of constacyclic codes over some chain rings is given, as well as conditions on the equivalence between constacyclic codes over finite chain rings and cyclic codes. As a special case, we consider the structure of $(\alpha + \beta p)$ constacyclic codes of length $p^s$ over $GR(p^e,r)$. Besides contributing to what is known concerning this class of codes, our motivation in studying these codes comes from the fact that repeated root cyclic codes contains many optimal codes, and the decoding complexity can be low as shown by Van Lint in the binary case [@lint] and Byrne et al. [@byrne] for codes over $Z_4$. Furthermore, repeated root cyclic codes have found applications in DNA computing [@watada]. The remainder of this paper is organized as follows. In Section 2, we give some preliminaries results concerning finite chain rings. Section 3 gives conditions on the scalar equivalency between constacylic codes and cyclic codes over finite fields (for both simple and repeated roots). In Section 4, we generalize some results of Section 3 to finite chain rings. Finally, the structure of $(\alpha + \beta p)$-constacyclic codes of length $p^s$ over $GR(p^e,r)$ is considered in Section 5. Preliminaries ============= A finite chain ring is a finite local, principal commutative ring $R$ with $1\neq 0$ such that its ideals are ordered by inclusion. Hence if $\langle \gamma \rangle$ is the maximal ideal of the finite chain ring $R$, then $ \gamma $ is nilpotent with nilpotency index some integer $e$. The ideals of $R$ form the following chain $$<0>= \langle\gamma^e\rangle \subsetneq \langle\gamma^{e-1}\rangle \subsetneq \ldots \subsetneq \langle\gamma\rangle \subsetneq R.$$ The simplest examples of finite chain rings are the finite fields. Since they are chain rings with nilpotency index 0, the nilradical of $R$ is $\langle\gamma\rangle$, so all the elements of $\langle\gamma\rangle$ are nilpotent. Therefore the elements of $R\setminus \langle\gamma\rangle$ are units. We denote this group by $R^*$. Since $\langle\gamma\rangle$ is a maximal ideal, the residue ring $\frac{R}{\langle\gamma\rangle}$ is a field which we denote by $K$. The natural surjective ring morphism is given by $$\label{eq:over} \begin{split} \mu: R& \longrightarrow K\\ a &\longmapsto \mu (a)=a +\langle \gamma \rangle \end{split}$$ The map given in (\[eq:over\]) extends naturally to a map from $R[x] \longrightarrow K[x]$. A polynomial $f$ of $R[x]$ is called basic irreducible if $\mu(f)$ is irreducible in $K[x]$. Let $|R|$ denote the cardinality of $R$. If $|K|=q=p^r$ for some integer $r$, then $$\label{cardinality-of-R} |R|=|K|\cdot|\langle\gamma\rangle|=|K|\cdot |K|^{e-1}=|K|^e=p^{er}.$$ A code $C$ of length $n$ over $R$ is a subset of $R$. If the code is a submodule we say that the code is linear. Here, all codes are assumed to be linear. \[lem:cardinal2\]([@Ana]) Let $R$ be a finite commutative chain ring with maximal ideal $\langle \gamma \rangle $, residue field $K$ and nilpotency $e$. Then the following hold: 1. the distinct proper ideals of $R$ are $\langle \gamma^i\rangle$, $i=1,2,\ldots,e-1$; 2. for $i=1,2,\ldots,e-1$, $|\langle \gamma^i\rangle|\, =\,|K|^{e-i} $. A special case of finite chain rings are the called Galois rings. The Galois ring $GR(p^e,r)$ is a ring of characteristic $p^{e}$ and cardinality $ p^{er}$. We have $ GR(p^e,1)={\mbox{\msbm Z}}_{p^e}$ and $ GR(p,r)= F_{p^{r}}$. The Galois ring $GR(p^e,r)$ is a local ring with maximal ideal $\langle p \rangle = p GR(p^e,r)$ and residue field $GR(p^e,r) /p GR(p^e,r) = F_{p^{r}}$. If $ f(x)\in {\mbox{\msbm Z}}_{p^e}[x]$ is a monic basic irreducible polynomial of degree $r$, then the Galois ring of degree $r$ over ${\mbox{\msbm Z}}_{p^e}$ is the residue class ring $$GR(p^e,r)\,=\,{\mbox{\msbm Z}}_{p^e}[x] /(f(x)).$$ If $\xi$ is a root of $f(x)$, then $GR(p^e,r) = {\mbox{\msbm Z}}_{p^e}[\xi]$, i.e., $GR(p^e,r)$ is a free module of rank $r$ over ${\mbox{\msbm Z}}_{p^e}$ with $\{1,\xi;\xi^{2},\dots,\xi^{r-1} \} $ as a basis. All Galois rings of the same orders are isomorphic. There exists an element $\xi$ of order $p^{r}-1 $ in $GR(p^e,r)$ called a primitive element of $GR(p^e,r)$, $\xi$ is a root of a unique monic basic primitive polynomial of degree $r$ over ${\mbox{\msbm Z}}_{p^e}$ and dividing $ x^{p^{r}-1}-1$ in ${\

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).toHaveBeenCalledTimes(1); })); }); }); Raman Characterization of Nanoparticle Transport in Microfluidic Paper-Based Analytical Devices (μPADs). There is great interest in the use of microfluidic paper-based analytical devices (μPADs) for low-cost diagnostics. In this contribution, we illustrate the utility of Raman spectral imaging for both μPAD characterization and for quantification of the transport of applied reagents and analytes within these devices. We evaluated the transport of nanoscale particles within μPADs using a suite of differentially functionalized gold (AuNP) and silver (AgNP) nanoparticles with diameters of 8-64 nm. Nanoparticle transport within the cellulose matrix was characterized by collection of both Raman and surface-enhanced Raman spectroscopy (SERS) spectral maps that enabled differentiation of cellulose fibers and characterization of analyte deposition patterns. The transport of citrate (cit), BSA, PEG, PVP, and DNA functionalized AuNP and AgNP in wax-printed μPADs was primarily affected by nanoparticle surface chemistry rather than particle size or core composition. Sample pH (3-10) influenced the transport of 15 nm BSA-cit-AuNP, but not 15 nm cit-AuNP, because of the effects of solution pH on the charge and conformation of BSA. Derjaguin, Landau, Verwey, and Overbeek theory (DLVO) and extended DLVO (xDLVO) theory are used to explain the collected experimental results.Its a Pop figurine of my favorite Game of Thrones character. Daenerys Targaryen everybody!!!!! And I also got a gift card to Chipotle! Thank you so much.Jackson Joshua, 14 Mar 2013Whats saddening is that Samsung needs an overclocked 8 core processor & 2 GB RAM to beat a... morethat's very true and it clearly shows the amount of 'innovation' at Samsung. Bigger in some cases is definetly not better. Can some advice, all feature they shows are of S4 or they are in S4 because of Jelly Bean 4.2.2 I am using Note2 if these features of OS than I'll automatically get this when I get an update....... Thanks in advance... Azady, 14 Mar 2013despite i hate the design, but there is no more option for me to choose either this or htc one... moreit just lunched the design is slightly different from the alleged phone published, if you look at front cam u will notice the cam lens are bigger, the design is actually nice, it has great features, will buy it for sure i am watching it right now go to youtube write 'Samsung UNPACKED 2013 Livestream' to watch it live. The best phone? Its a joke? This is the same phone -.- than note 2 or S3 -.- same design, same quality -.- this is not funny. Xperia Z or Optimus G or HTC One are better than this phone and the 8 cores not faster than Qualcomm SnapDragonS4 pro or Qualcomm 800. ThomasCarlsson, 14 Mar 2013Android is more or less dead because Google have removed Adaway and Adfree Android and Adblock... moreYou can get all that from xda-developers. Their host file to prevent ads is actually helluva lot better, too.Main menu Tag Archives: ornithologist Someone(s) once commented that Pete Dunn is a writer who birds, while Kenn Kaufman is a birder who writes. (Both of these men are well known in the birding community and have published countless books each.) I am in no means a writer. Or at least I don’t consider myself to be one. However, I think that if you substitute writer with educator, this phrasing might work for me. Thus, Jordan is a birder who educates, not the other way around. JER giving a bird banding demonstration to a kindergarten class in Texas I bring this up because several people (all of whom don’t know each other) have brought up the idea/suggestion that I be a teacher. While that’s always been an option and kept on the back burner list of possibilities, I just don’t see it being the vocation I make my life’s career out of. Being a teacher isn’t the job that I feel compelled to rush out and sign up for. Being a bird educator/outreacher of some kind though, that is something I can day dream about. Why dismiss a traditional teaching position so quickly when it comes up? Well, to be honest, there aren’t any birds…or at least not enough. Yes, there are programs (some of which I’ve worked for and am connected with) that can be brought into the classroom. Yes, there are lesson plans and curriculum involving birds and bird information. But for me, that’s not enough. Why not just be an ornithologist then? This situation is the complete opposite of teaching though. Where are the people to share the bird information with? Where is the opportunity to talk and engage with people from other backgrounds to get new perspectives and always push me/us to be the best, most scientific ornithologist as possible? Where is the ability to be continually re-energized by the excitement and questions and wonder seen in other people that are being exposed to birds and bird research. A summer job I once had seems like a great match then. (I put on educational bird events for kids.) Here’s the only thing, the constant change in kids was basically the only thing that made it new and exciting. We had a set program that we did…every, single time. To be honest, after a while it started to get a little repetitive for me. The issue I see with doing something that involves so much repetition is that I fear I might lose some of my enthusiasm or spark. This is why I need the balance of both worlds. What I may lack in terms of formal education background or training (as of now), I make up with passion. The research aspect keeps me learning and giving me the ability to always have new material to share with others. The outreach component gives me the opportunity to feel like I’m making a difference and doing my part for science and the environmental movement. How do I describe the balance of ornithology and education/outreach? Liaison. That is what I want to be. I don’t know how else to describe it. I want to take the science and ornithological research and translate that for everyone else to understand. I’m finding it very difficult to do this though. With the way things are today, it seems as though the choice is either classroom or lab. I’m not happy settling with only those two options. This all probably sounds stubborn or greedy, but if I’m going to follow what I’ve been taught and stressed by countless people over my life, then I need to “love what I do and do what I love.” And birds and talking about birds is what I love.Q: R: Column Heading Conversions I have the following dataset. My objective is to understand how numbers and mammals and birds are there in the two types of locations. df1: Location Type Cat Mouse Dog Chicken Turkey Horse 1 1 0 0 1 0 1 1 0 0 1 0 1 0 2 1 1 1 1 1 1 2 0 1 0 0 0 0 1 1 1 0 0 1 0 I want it to read as df2: Location Type M M M B B M 1 1 0 0 1 0 1 1 0 0 1 0 1 0 2 1 1 1 1 1 1 2 0 1 0 0 0 0 1 1 1 0 0 1 0 with 'M' denoting Mammal and 'B' denoting Bird I tried to manually enter the data into my.csv file and use it in R, however, the file gets read as df2: Location Type M M1 M2 B B1 M3 1 1 0 0 1 0 1 1 0 0 1 0 1 0 2 1 1 1 1 1 1 2 0 1 0 0 0 0 1 1 1 0 0 1 0 I am not sure why each 'M' or 'B' column gets numbered separately, how could I prevent this from happening or I also have the animal type classified as mammal and bird in another dataframe as below dfanimal: Name of Animal Mammal/Bird Cat Mammal Dog Mammal Mouse Mammal Chicken Bird Turkey Bird Horse Mammal If there is a way for me to directly work my way with the dataframes, df1 and dfanimal? Would be very thankful for any help. A: After you manually change the column names, you can use check.names = FALSE while importing the

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start of the compressed data. */ start_byte = page_offset(bvec.bv_page) - disk_start; /* we haven't yet hit data corresponding to this page */ if (total_out <= start_byte) return 1; /* * the start of the data we care about is offset into * the middle of our working buffer */ if (total_out > start_byte && buf_start < start_byte) { buf_offset = start_byte - buf_start; working_bytes -= buf_offset; } else { buf_offset = 0; } current_buf_start = buf_start; /* copy bytes from the working buffer into the pages */ while (working_bytes > 0) { bytes = min_t(unsigned long, bvec.bv_len, PAGE_SIZE - buf_offset); bytes = min(bytes, working_bytes); kaddr = kmap_atomic(bvec.bv_page); memcpy(kaddr + bvec.bv_offset, buf + buf_offset, bytes); kunmap_atomic(kaddr); flush_dcache_page(bvec.bv_page); buf_offset += bytes; working_bytes -= bytes; current_buf_start += bytes; /* check if we need to pick another page */ bio_advance(bio, bytes); if (!bio->bi_iter.bi_size) return 0; bvec = bio_iter_iovec(bio, bio->bi_iter); prev_start_byte = start_byte; start_byte = page_offset(bvec.bv_page) - disk_start; /* * We need to make sure we're only adjusting * our offset into compression working buffer when * we're switching pages. Otherwise we can incorrectly * keep copying when we were actually done. */ if (start_byte!= prev_start_byte) { /* * make sure our new page is covered by this * working buffer */ if (total_out <= start_byte) return 1; /* * the next page in the biovec might not be adjacent * to the last page, but it might still be found * inside this working buffer. bump our offset pointer */ if (total_out > start_byte && current_buf_start < start_byte) { buf_offset = start_byte - buf_start; working_bytes = total_out - start_byte; current_buf_start = buf_start + buf_offset; } } } return 1; } Q: Save file with Russian letters in the file name I have this Python script that takes the info of a webpage and then saves this info to a text file. But the name of this text file changes from time to time and it can changes to Cyrillic letters sometimes, and some times Korean letters. The problem is that say I'm trying to save the file with the name "бореиская" then the name will appear very weird when I'm viewing it in Windows. I'm guessing I need to change some encoding at some places. But the name is being sent to the open() function: server = "бореиская" file = open("eu_" + server + ".lua", "w") I am, earlier on, taking the server variable from an array that already has all the names in it. But as previously mentioned, in Windows, the names appear with some very weird characters. A: tl;dr Always use Unicode strings for file names and paths. E.g.: io.open(u"myfile€.txt") os.listdir(u"mycrazydirß") In your case: server = u"бореиская" file = open(u"eu_" + server + ".lua", "w") I assume server will come from another location, so you will need to ensure that it's decoded to a Unicode string correctly. See io.open(). Explanation Windows Windows stores filenames using UTF-16. The Windows i/o API and Python hides this detail but requires Unicode strings, else a string will have to use the correct 8bit codepage. Linux Filenames can be made from any byte string, in any encoding, as long as it's not ASCII "." or "..". As each system user can have their own encoding, you really can't guarantee the encoding one user used is the same as another. The locale is used to configure each user's environment. The user's terminal encoding also needs to match the encoding for consistency. The best that can be hoped is that a user hasn't changed their locale and all applications are using the same locale. For example, the default locale may be: en_GB.UTF-8, meaning the encoding of files and filenames should be UTF-8. When Python encounters a Unicode filename, it will use the user's locale to decode/encode filenames. An encoded string will be passed directly to the kernel, meaning you may get lucky with using "UTF-8" filenames. OS X OS X's filenames are always UTF-8 encoded, regardless of the user's locale. Therefore, a filename should be a Unicode string, but may be encoded in the user's locale and will be translated. As most user's locales are *.UTF-8, this means you can actually pass a UTF-8 encoded string or a Unicode string. Roundup For best cross-platform compatibility, always use Unicode strings as in most cases they will be translated to the correct encoding. It's really just Linux that has the most ambiguity, as some applications may choose to ignore the default locale or a user may have changed their locale to a non-UTF-8 version. Q: ProgressIndicator freezes when button is pressed. JavaFX I'm using a indicator progress set to -1.0 to show some loading while loginprocess is running. But when I press the Enter button and start my executor with the loginProcess, my interface stays freezed even if I use Plataform.runLater to set visible my ProgressIndicator. My button event: public void initManager(final LoginManager loginManager) { btnEntrar.setOnAction(new EventHandler<ActionEvent>() { @Override public void handle(ActionEvent event) { String email = loginTxtField.getText().trim(); String token = tokenTxtField.getText().trim(); if (email.equals("")) { Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", "Digite o e-mail"); } }); return; } try { Future future = loginProcess(email, token); showLoginLoading(future); future.get(); if (!loginGatewayFailed &&!loginTargetAppFailed) { Login loginTargetApp = new Login(email, null, null); loginManager.autheticated(loginTargetApp, loginGateway, gateway, file); } else { if (loginTargetAppFailed) { Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", loginTargetAppFailedCause); } }); } else { if (loginGatewayFailed) { Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", loginGatewayFailedCause); } }); } } } } catch (final Exception ex) { Logger.getLogger(LoginController.class.getName()).log(Level.SEVERE, ex.getMessage()); Platform.runLater(new Runnable() { public void run() { Dialog.showError("Erro", ex.getMessage()); } }); } } }); } My loginProcess: public Future<?> loginProcess(String email, String token) throws Exception { // MY PROCESS return Executors.newSingleThreadExecutor().submit(new LoginTask(this, email, token)); } catch (Exception e) { Logger.getLogger(LoginController.class.getName()).log(Level.SEVERE, e.getMessage()); throw e; } } method showLoginLoading: private void showLoginLoading(Future future) { while (!future.isDone()) { Platform.runLater(new Runnable() { @Override public void run() { progressInd.setVisible(true); // progressInd.setProgress(-1.0); } }); } } A

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videos to add to 3 other pages instead of images. I need it to work the same way as the homepage. And a way to change them if I need to. Should be very easy to do as you can already do o...<?xml version="1.0" encoding="UTF-8"?> <project version="4"> <component name="ProjectModuleManager"> <modules> <module fileurl="file://$PROJECT_DIR$/app/app.iml" filepath="$PROJECT_DIR$/app/app.iml" /> <module fileurl="file://$PROJECT_DIR$/seekbar.iml" filepath="$PROJECT_DIR$/seekbar.iml" /> </modules> </component> </project>![](envhper00434-0104.tif "scanned-page"){.109} ![](envhper00434-0105.tif "scanned-page"){.110} ![](envhper00434-0106.tif "scanned-page"){.111} ![](envhper00434-0107.tif "scanned-page"){.112} ![](envhper00434-0108.tif "scanned-page"){.113} ![](envhper00434-0109.tif "scanned-page"){.114} ![](envhper00434-0110.tif "scanned-page"){.115} ![](envhper00434-0111.tif "scanned-page"){.116} ![](envhper00434-0112.tif "scanned-page"){.117} ![](envhper00434-0113.tif "scanned-page"){.118} ![](envhper00434-0114.tif "scanned-page"){.119} Parasailing Old Orchard Beach Parasailing with Old Orchard Beach Parasailing & Jet Ski will be the Highlight of your trip. The waters off of Old Orchard Beach will be the starting point for your aerial adventure, culminating in an unbelievable view from high above the waters of Old Orchard Beach. You will float effortlessly from our parasail canopy as you soar along with the gulls and frigates, peering down into the water. From your lofty perch, you will be able to take in the fabulous view of Old Orchard Beach providing you with an unparalleled visual experience. How it works: Old Orchard Beach Parasailing utilizes the newest technology and systems to provide anyone with a safe, soft, controlled parasailing experience. Our state of the art vessel is built solely for your parasailing enjoyment. Up to six people can go out on the boat for the excursion. You and up to three of your friends or family members can ride in the parasail together and share the moment–from a seated position on the back deck you will feel the boat pull away as you almost imperceptibly lift up into the air. The Kevlar towline is reeled out from a winch so smoothly that it feels as if the boat simply leaves you while your view becomes increasingly more beautiful as you climb higher and higher, leaving the gravity-bound world below. For the more adventurous, we can provide an incredible experience we call a ”free fall” where the captain slows the boat and lets you float down with the parachute until you almost touch the water, then he hits the throttle and up you come again! Of course, we can add a little "splash" as well, for those of you who prefer to cool off before returning to the deck. Everyone lands softly back onto the deck as the captain reels the line back in, compelling the parachute to return to the boat every time. By the way, our captains are US Coast Guard certified and have years of parasailing experience. 10 So.3d 722 (2009) Sonja JAMES, et al. v. STATE FARM MUTUAL AUTOMOBILE INSURANCE COMPANY, et al. No. 2009-CC-0967. Supreme Court of Louisiana. June 19, 2009. Granted. The case is remanded to the trial court for reconsideration of its ruling *723 in light of Gingles v. Dardenne, 08-2995 (La.3/13/09), 4 So.3d 799. KIMBALL, C.J., would deny the writ. JOHNSON, J., would deny the writ. KNOLL, J., would deny the writ. Indiana Mom Strikes Plea Deal In Child Neglect Case An Indiana mother has reached a plea deal with prosecutors in a child neglect case involving three of her severely malnourished children and her 14-month-old daughter who sustained a skull fracture. Sheena A. Zanghi, 24, was charged Monday with four counts of neglect of a dependent, a charge that could bring up to three years in prison. Details on the plea agreement were not released, with Henry Circuit Court 1 Judge Mary Willis setting sentencing for the tentative date of Aug. 13. Although Zanghi reached a plea deal with prosecutors back in February, a judge rejected the agreement in April, according to WTHR. ADVERTISEMENT Thanks for watching! Zanghi and her four children were discovered by police in June 2014 living in a mobile home with no running water, electricity or a functioning bathroom, according to the Muncie Star Press. Vincent Zanghi, Sheena's 36-year-old husband, also lived with them. Sheena's 81-year-old grandfather, Earl Lee Larue, who ran the nearby trailer supplying some electricity to his granddaughter's trailer, told police that Vincent assaulted him, and that he was likely abusing the children, too, according to The Inquisitr. The officers who arrived at the scene recall seeing broken glass, wood and nails outside the home--easily accessible to the children. They also remember smelling urine before entering the home, WXIN reported. ADVERTISEMENT Thanks for watching! ADVERTISEMENT Thanks for watching! All four children had cuts and bruises over their bodies, which were reportedly caused by the pit bull puppies Zanghi owned. The three youngest children were so malnourished that they exhibited "poor linear and brain growth", placing them at risk for developmental delays. A child abuse specialist was also concerned that at least one of Zanghi's children had suffered from physical abuse.20 Board Games Based on ’70s and ’80s TV Shows Better than trading cards, less useful than a lunchbox, and perfect for weekend collecting, there are a staggering number of board games based on classic television shows from the ‘70s and ‘80s still knocking around. Here are 20 of the very best. 1. Happy Days An almost totally Fonzie-focused endeavor, the entire aim of the Happy Days game is to collect enough “cool points” to impress the Fonz. Along the way, points are tallied by lighting up Arnold’s jukebox and time passes by finding “sumthin’ to do.” 2. Cheers How’s your Cheers knowledge pool? Not too deep? Don’t worry, you can almost wing it with this trivia-based game—if you pay enough attention to hints about how the various bar occupants acted on the show, which pepper gameplay. Watch out for “Normie’s Olympics,” though, a mini-game that uses the sort of skills that only a drunk dude could master (it involves both balance and total carelessness). 3. Barney Miller The Barney Miller board game has a few surprises up its cardboard sleeves—no one gets to play the eponymous cop and it’s essentially a bettor’s version of the match game. Is this how cops actually do their job? Perhaps—at least on television. 4. Knight Rider This “high speed adventure game” doesn’t come with a tiny David Hasselhoff cutout, but it does require players to travel an admittedly “never-ending road” without getting hijacked. Clear “Trouble Spots” and hope that your robot car doesn’t get stolen—something you’d think K.I.T.T. would be far too clever to allow anyway. 6. The A Team We pity the fool who doesn’t feel instantly compelled to play the board game version of The A Team once they hear what it’s about. Curiously focused on a mission to retrieve a stolen soda recipe from an evil band of apparently very weird baddies, the goofy action of the classic show is in full effect in this one-dimensional quest. 7. Welcome Back, Kotter Intent on capitalizing on its trademark “up your nose with a rubber hose” tagline, the Welcome Back, Kotter game is entirely centered on said hose. The aim of the game is to use cards to spell out the entire phrase, and the “winner” ultimately gets a small piece of, you guessed it, rubber hose to celebrate their victory. 8. CHiPS It would be pretty unsafe to attempt to replicate the highway hijinks of CHiPS the show, so this board game will have to suffice. Each player takes on the role of a motorcycle cop, bound for the sort of glory that will only come after capturing no less than four vehicular b

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394, 14, 9888, 5685, 30525, 40, 757, 33986, 66, 19523, 4611, 187, 187, 40, 757, 33986, 66, 19523, 4611, 313, 6448, 9847, 4534, 80, 13, 1638, 2552, 16648, 10, 310, 271, 9890, 23721, 13, 16518, 13, 22531, 285, 18468, 665, 310, 6571, 1929, 347, 253, 2022, 1963, 9141, 273, 253, 49562, 285, 3909, 48386, 757, 14275, 26479, 13, 534, 2335, 1659, 275, 3919, 4059, 15, 187, 187, 1909, 247, 9835, 5974, 273, 17388, 387, 253, 2499, 273, 20254, 5738, 13, 19523, 4611, 7416, 418, 16405, 12683, 1464, 1253, 45, 3604, 23060, 285, 369, 10544, 21209, 46395, 263, 275, 12000, 1321, 15, 14566, 644, 39372, 432, 326, 3128, 13, 344, 369, 581, 273, 253, 23569, 2758, 273, 253, 20254, 44316, 20911, 382, 25678, 275, 8210, 285, 369, 697, 28179, 323, 767, 1107, 15, 496, 436, 5350, 13, 344, 369, 13084, 323, 1907, 644, 271, 562, 33065, 31409, 273, 20254, 16642, 285, 273, 253, 48386, 757, 5595, 1023, 9457, 7295, 434, 21935, 273, 659, 15, 4744, 434, 8647, 266, 587, 275, 28792, 15, 831, 1390, 2362, 3977, 19523, 4611, 281, 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1963, 9141, 273, 21231, 67, 2865, 7067, 15, 16427, 13, 271, 3909, 26479, 327, 12683, 16713, 434, 14275, 15, 4794, 281, 253, 4750, 13, 374, 15, 1812, 3041, 48386, 2458, 313, 3571, 15, 19, 6, 273, 512, 13410, 11163, 10, 13640, 275, 253, 3909, 26479, 285, 11289, 15, 18, 6, 273, 731, 313, 3529, 310, 281, 1333, 8026, 15, 23, 6, 273, 512, 13410, 11163, 10, 14285, 4754, 15, 831, 369, 2217, 323, 19523, 4611, 285, 521, 18409, 281, 354, 7041, 12683, 16713, 434, 14275, 432, 9972, 275, 9847, 4534, 80, 327, 253, 2360, 273, 3127, 3919, 15, 496, 253, 8461, 13, 3578, 346, 615, 1851, 684, 323, 14275, 3, 497, 10544, 1512, 27, 19523, 4611, 369, 253, 954, 14285, 7431, 342, 13620, 13, 18950, 14682, 13008, 15, 187, 187, 1328, 556, 4102, 5485, 247, 23978, 2567, 275, 43372, 571, 13, 4907, 3035, 76, 1406, 375, 13, 25251, 2067, 50150, 84, 1580, 4765, 15, 1583, 1750, 281, 452, 5728, 1249, 3041, 8918, 13, 1097, 432, 48386, 757, 952, 285, 643, 946, 28457, 15, 187, 187, 4941, 187, 187, 1413, 27, 25892, 10782, 187, 1413, 27, 14316, 952, 187, 1413, 27, 39685, 292, 757, 13557, 187, 1413, 27, 39685, 292, 382, 13557, 187, 1413, 27, 8836, 432, 9847, 4534, 80, 187, 1413, 27, 938, 394, 14, 9888, 9890, 13557, 187, 1413, 27, 1797, 296, 14, 9888, 9890, 13557, 2042, 368, 4288, 407, 2329, 390, 3297, 275, 21440, 1309, 634, 9836, 8729, 24779, 13, 368, 403, 417, 247, 6867, 5396, 22777, 15, 380, 1685, 310, 253, 954, 1846, 4438, 273, 4616, 285, 625, 952, 3297, 342, 3858, 285, 17772, 1309, 824, 19055, 685, 275, 21440, 285, 12141, 9910, 13, 2556, 281, 247, 3313, 24046, 17136, 44115, 313, 47, 3528, 48, 10, 1304, 15, 6037, 4288, 310, 2761, 22879, 15, 187, 187, 2773, 753, 13, 954, 952, 403, 9100, 625, 327, 4288, 685, 597, 858, 253, 1390, 673, 824, 271, 5763, 369, 4824, 562, 275, 4695, 14, 2693, 15, 187, 187, 1276, 4850, 16869, 22710, 32, 187, 187, 510, 427, 3528, 48, 6630, 13, 534, 369, 4824, 562, 275, 4059, 14, 1010, 13, 556, 767, 9351, 273, 6128, 327, 253, 4283, 4096, 273, 247, 7408, 1128, 783, 1921, 1293, 534, 253, 7408, 812, 417, 452, 644, 20023, 15, 187, 187, 6436, 13, 627, 310, 247, 3064, 275, 253, 5133, 275, 534, 6128, 452, 644, 5728, 323, 1027, 6378, 15, 1198, 13319, 272, 13, 27335, 285, 37481, 28, 1786, 285, 3739, 26742, 28, 285, 12701, 13, 247, 6983, 2180, 273, 23412, 1897, 556, 644, 2668, 15, 1198, 2136, 28, 2675, 28, 7231, 285, 31514, 13485, 28, 4730, 285, 3733, 285, 773, 39658, 995, 247, 1884, 14, 1201, 6983, 2180, 556, 644, 2668, 15, 10300, 253, 3064, 275, 16182, 13, 253, 767, 2550, 320, 2429, 15, 3813, 13, 359, 30648, 253, 3894, 273, 19055, 407, 4283, 4096, 327, 253, 3720, 273, 253, 6983, 2180, 908, 15, 187, 187, 688, 1097, 9050, 13, 670, 581, 275, 2620, 18294, 2361, 1907, 4783, 327, 387, 1878, 581, 13463, 7408, 15, 187, 187, 688, 253, 23412, 14, 1201, 7140, 13, 773, 15356, 285, 3739, 3, 369, 253, 4283, 4096, 273, 253, 7408, 275, 1097, 11393, 285, 10106, 3672, 13, 15890, 323, 3387, 6, 273, 512, 4288, 15, 733, 369, 3560, 407, 27335, 2425, 313, 1671, 10970, 496, 253, 1884, 14, 1201, 6983, 2180, 13, 2675, 12941, 403, 253, 4283, 4096, 273, 247, 7408, 13, 15890, 323, 247, 7863, 11614, 15, 23, 6, 273, 512, 4288, 15, 187, 187, 21166, 670, 19055, 323, 2136, 13, 2675, 4606, 13, 7231, 13, 11331, 390, 643, 6378, 369, 13037, 342, 247, 1884, 14, 1201, 673, 2180, 275, 2564, 15, 8404, 19055, 20184, 323, 11422, 15, 19, 6, 273, 19055, 1160, 689, 253, 1390, 1884, 1897, 275, 11393, 3672, 285, 11439, 15, 18, 6, 275, 10106, 3672, 15, 187, 187, 34, 5301, 281, 247, 2074, 6630, 4824, 562, 275, 4695, 14, 2693, 2722, 326, 253, 2408, 273, 2583, 5262, 556, 2559, 3012, 323, 512, 9351, 273, 19055, 15, 380, 5962, 6054, 556, 644, 323, 12701, 19055, 387, 31389, 5294, 3560, 407, 1786, 285, 3739, 26742, 313, 20922, 10970, 187, 187, 510, 954, 3939, 1375, 275, 2426, 273, 26742, 310, 47766, 15, 36388, 581, 275, 767, 18294, 313, 16576, 5693, 15, 23, 2673, 275, 326, 1375, 2361, 13463, 19055, 275, 253, 1390, 23412, 1897, 390, 253, 1390, 1884, 1897, 1078, 253, 6630, 15, 733, 369, 3560, 407, 15101, 607, 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745, 271, 19076, 2137, 15, 16257, 13, 1841, 755, 25594, 875, 10035, 285, 16739, 13, 24336, 434, 7586, 15, 29569, 16681, 322, 1831, 18535, 5536, 29923, 38700, 1131, 285, 5145, 5654, 3289, 3735, 2822, 34370, 484, 311, 187, 187, 30641, 375, 864, 7381, 285, 22404, 2312, 670, 17749, 492, 6977, 34756, 13, 20510, 375, 864, 7381, 434, 3906, 2296, 187, 187, 37881, 588, 3794, 604, 747, 8215, 17634, 403 ]

1966. Kärnter Exilantenschicksal in der Zeit der Gegenreformation – ein Beitrag zur Geschichte der religiös motivierten Vertreibungspolitik Erzherzog Ferdinand II. in Kärnten in den Jahren 1596-1637. Yearbook of the history about the Protestantism in Austria, Jg. 112, Wien, 1996. Michaelis, Hans-Thorald, Das erste deutsche Bundesschießen 1862 in Frankfurt am Main – eine deutsche Tragödie des Unbewältigten, in: Innsbrucker Historische Studien 16/17 (1997), S. 361-406 Geschichte der Familie von Boehmer in Fortführung der von Hugo Erich von Boehmer im Jahre 1982 verfassten Genealogie der von Justus Henning Boehmer abstammenden Familien sowie einiger der mit ihnen verschwägerten Familien. Rheinische Verlagsanstalt, Bad Godesberg, 1978, 248 S.; heading in Library of Congress. Different genealogical publications for the journal „Genealogie“, and also for „Ostdeutsche, Norddeutsche und Mitteldeutsche Familienkunde“ of Degener-Verlag, 91610 Insingen. Hans-Thorald Michaelis works in the catalogue from the German National Library References Category:1925 births Category:2004 deaths Category:German genealogists Category:German male non-fiction writers Category:20th-century German historiansGianluca Busato Gianluca Busato (born Treviso, 14 May 1969) is an Italian entrepreneur, engineer, activist and politician who is mostly known as the main organiser of the unofficial and online Venetian independence referendum, which took place in March 2014. As a university student of Engineering at the University of Padua, Busato joined Liga Veneta–Lega Nord and was elected municipal councillor in Casier. Having been expelled from that party, he was one of the founding members of the Padanian Independentist Movement in 1997 and was its spokesperson for two years. In this capacity, he was convicted for having been an outspoken supporter of Padania and of the Venetian Most Serene Government's seizure of St. Mark's Campanile in Venice. This last event led Busato to abandon his early Padanist feelings and to adhere to the Venetian independence movement. According to his own words, Busato returned to active politics only after the depenalisation of "crimes of opinion". In 2006 he wrote a pamphlet on independence and was a founding member of the Venetians Movement and, a year later, he launched the libertarian and avowedly separatist Venetian National Party (PNV), and served as its national secretary from 2008 to 2010. He was later active, often taking leadership roles, in a succession of separatist outfits, all emerged from bulk of the PNV: Veneto State (2010–2012), Venetian Independence (2012–2013), Plebiscite 2013 (2013–2014) and, finally, Veneto Yes (since 2013). In 2014 Busato came to regional prominence as the main organiser of Plebiscito.eu, an online referendum on Veneto's independence. According to the staff, 2.36 million Venetians (63.2% of all eligible voters) participated in the online referendum and 89.1% of them (that is to say 56.6% of all eligible voters) voted yes. This was enough for Busato and his followers to proclaim Veneto's independence from Italy in Treviso on the night of 21 March. In the poll, ten "delegates for independence" were elected too: Busato was the most voted candidate with 135,306 preference votes. He has recently opened a crypto company in Slovenia, named Enkronos, launching several ICOs since 2018. They claim to have collected 12 million dollars, both from Venetian people and other speculators. References Category:1969 births Category:Living people Category:Venetian politicians Category:Venetist politicians Category:People from Treviso Category:20th-century Italian politicians Category:21st-century Italian politiciansIf you travel by air or stay in hotels during your domestic jaunts, you are not a typical Indian tourist. The bus is the most common mode of transport and more people stay with friends and relatives during such trips than in hotels and guest houses, according to a National Sample Survey Organisation (NSSO) report. Air travel is almost negligible. That said, most people are spending more on travel than they did the last time such an exercise was carried out in 2008-09. What gets Indians travelling? The NSSO survey, which was carried out in 2014-15, has two kinds of responses on the leading purpose of a trip—the reason without which the trip could not have been undertaken. However, there is a difference in the manner in which responses have been collected for different purposes. For holidaying, leisure and recreation; health and medical tourism; and shopping, a recall period of 365 days has been taken. For business; social; religious and pilgrimages; education and training and “others", a 30-day recall period has been taken. Given the difference in methodology, the two cannot be compared. Therefore, we analyse the share of trips by leading purpose on the basis of the recall period used. In both categories, about one in five households reported having gone on at least one overnight trip. In the 365-day category, “health and medical" was the leading purpose of the trip in both rural and urban areas, accounting for 40% of all travel. It was followed by leisure activity (35%). In the 30-day recall period, social visits are the leading purpose of a trip, accounting for a massive 86.6% of all travel. Information about trips for business, social reasons, religious, educational or other purposes was gathered with a 30-day time period in mind. Social trips accounted for 87.2% of trips made over the last 30 days in rural areas and 83.1% in urban areas. A comparison to a similar survey carried out in 2008-09 shows that the amount of money spent has increased significantly for all kinds of trips. The biggest rise has been for shopping trips at 313%, followed by health and medical tourism (291%). The most active state in terms of tourism is Kerala. Nearly one in two households (around 48.6%) in that state reported overnight trips in the last 365 days or the last 30 days before the survey. It was followed by Himachal Pradesh (48%) and Jammu and Kashmir (47.8%). There is a surprisingly narrow gap between urban and rural India when it comes to domestic tourism. There was no difference at an all-India level in the amount of travelling done by rural and urban households, the report said. It noted that both were equal in terms of reporting at least one overnight trip over the previous year for purposes which included leisure, besides health-related trips and shopping expeditions. There were some state-level differences. In Assam and Jharkhand, there was more travelling reported in the urban belt than in rural regions. In other states such as Maharashtra and Andhra Pradesh, people in rural areas travelled more. When they do travel, the bus is the most common mode of transport for India’s domestic tourists. This is true in both rural and urban areas. It accounts for 33.5% of travel in urban areas and 49.9% in rural areas. Trains and hired transport are the two other major modes of transport in both areas. Air travel is limited to 1.9% for urban and 0.1% for rural travel. Travellers stay far more with friends and relatives than at hotels and guest houses. Those from urban areas are more likely to stay in hotels. The “others" category in includes railway stations, waiting rooms, health clinics, nursing homes—even tents. The shortest kind of trips are those for shopping. They generally last two to three nights. Longer ones are those planned as leisure trips and last four days or more. The report noted that shopping trips happened in the winter. Religious trips and pilgrimages started in July and August. An interesting finding in the survey is the rise of the single female traveller. Lone women travellers account for a significant proportion of people travelling alone. And there is surprisingly little urban-rural gap among such travellers. If the number of women travelling alone accounts for 31% of all lone urban travellers, the corresponding number for rural areas is 30%. And the proportion of women travelling alone for shopping is higher in rural India. Religious travel or pilgrimages and social travel also see more lone women travellers as a proportion of total lone travellers in the rural segment. Subscribe to Mint Newsletters * Enter a valid email * Thank you for subscribing to our newsletter. Share ViaNarcotics cops Mike Lowrey and Marcus Bennett head up a task force investigating the flow of ecstasy into Miami. Their search leads to a dangerous kingpin, whose plan to control the city's drug traffic has touched off an underground war. Meanwhile, things get sexy between Mike and Syd, Marcus's sister.Story highlights Sporadic heavy artillery barrages and machine gun fire heard near Mariupol Poroshenko and Putin talk about ensuring truce lasts, Poroshenko's office says Russia will respond if new EU sanctions are

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for you to pour over. After reaching out to over 200 record shops across the country, here it is. Rhubarb Records are proud to bring you our Australian record store directory...Dig in. If we've somehow missed your store or you know of one that we have missed please feel free to contact us via email and we will update this list. We hope this directory will help you discover new Australian Indie Record Stores!Strava! Visit the TD Five Boro Bike Tour route map on Strava to get a detailed, turn-by-turn map of the event. You can even download the route to your Garmin or smartphone. And if you’re looking for training partners or some company on the ride, check out the Bike New York club on Strava. Don’t forget to upload your tour to Strava. All participating Strava cyclists will be entered to win 10 great prizes, like a Fitbit Surge, Strava Premium membership and Greenblender smoothie kit. HOW CAN I EDIT MY TEAM AND REGISTRATION DETAILS?As the world braces for a recession triggered by the coronavirus outbreak, venture capital–backed startups across several industries are making significant cuts to their employee numbers. Four companies have cut roughly 20% of their workforce in an effort to reduce cash burn rates and increase savings—online mattress retailer Eight Sleep, tech-enabled recruiting tool Triplebyte, hospitality startup The Guild, and luxury sleeper-bus service Cabin, according to people familiar with the companies. The number of jobs cut was relatively small—75 people across all four, ranging across both technical and nontechnical job roles—but they’re a harbinger of what is to come. Meanwhile, scooter rental service Lime is reportedly considering job cuts after terminating its operations in most of its markets.A micro-unit housing developer who hoped to build apartments at Fifth and Waller streets is now setting his sights on an East Cesar Chavez property – the site of a proposed Eastside hotel that galvanized neighborhood opposition – to construct the affordable housing complex. In March, real estate developer Taylor Wilson of Centec Management, LLC unveiled plans for Austin's largest micro-housing property: some 260 units averaging 400 square feet, primarily aimed at a low-income demographic. Wilson told the Chronicle that deal recently fell through after a longtime tenant at the site was unable to move out before 2017. But he said he's now close to finalizing terms to buy the property at 1207 E. Cesar Chavez from investors that include Brian and Bree Carrico – the husband-and-wife pair of would-be hoteliers whose proposed project in fast-gentrifying East Austin garnered broad community opposition (see: "East Side Hotel Denied," June 10). Eastside residents balked at the hotel plan, citing the likely increased traffic the proposed 65-room hotel would bring to an already congested East Cesar Chavez, and the city's Planning Commission sided with residents, voting 4-1 against granting a conditional use permit for the hotel. In a recent telephone interview, Carrico acknowledged he was in conversations with Wilson to sell the land; citing ongoing negotiations, he declined to provide more details. But Wilson says the land transfer is something of a foregone conclusion: "We have what I would call a firm handshake agreement to buy the site. We can get that site no problem; that's a done deal." But there's a new snag: Wilson says discussion with the owners of two needed lots in the development's footprint located at 1205 E. Cesar Chavez aren't moving as quickly as the discussions with the Carricos' investment team. Acquisition of those two lots – collectively comprising about one-fourth of an acre – would allow parking entry away from the congested East Cesar Chavez artery as community representatives would prefer, he said. Wilson has been apprising members of the East Cesar Chavez Neighborhood Planning Team for some weeks now on his plans for the land. A changed entry site would add to an already long list of changes from the original plans Wilson had envisioned. The rebooted project will be smaller and contain fewer units. Of the 151 units at 1207 E. Cesar Chavez, 128 would be micro-units – with a mixture of affordable and market-rate apartments – and 23 live/work units designed for owners of small businesses on the ground floor who also would be tenants. The original combination of partners is likely to change as well. And Wilson said the units will be prefabricated modular ones to be later assembled and stacked atop each other, speeding up completion by allowing site work to be performed simultaneously as off-site module construction. "My calculation is that it will save nine months," he said. "It can still be done in a high-caliber manner with tighter, better construction of units in a fraction of the time." Alberto Martinez of the East Cesar Chavez Neighborhood Planning Team – which was stridently opposed to the Carricos' hotel plans – is amenable to Wilson's project. He said the planning team members were appreciative of the approach by Wilson, a 24-year-old entrepreneur following his real estate developer father's footsteps, in communicating his plans with them. "We were very impressed by him," Martinez said in a recent phone interview. "We would welcome" the micro-units project, which would offer much-needed affordable housing for some on the Eastside where property rates have risen in light of commercial development. That tentative endorsement is in marked contrast to opposition to the scrapped hotel plans at that same site of land. "What is happening in East Austin is everyone wants to make as much as they can and the neighborhood be damned," said Martinez. "There's a lack of creativity. But this we would welcome." Even while acknowledging that he's a businessman trying to make a profit off his ventures, Wilson said the idea of building much-needed affordable housing in an area of the city where there is a critical need for it was further appealing. "Obviously, there's a good, ethical feeling you get when you're building something people want," he said. "From a business perspective, the returns on investment are not through the roof as in other business projects, but building a micro-unit deal is something new. To be on the leading edge in Austin for a new kind of development will open a lot of doors down the road."Pages Monday, June 8, 2015 As part of its "Diploma Counts" coverage, EdWeek is offering color coded maps of state graduation rates for various groups. It's a wonderful approach, letting viewers click quickly from group to group and experience the gaps as vivid changes. The darkest blue is used for the strongest results, while the darkest orange-brown identifies the weakest outcomes. Above, results for economically disadvantaged students, with Kentucky's 85% rate shown as well above the national average of 73%, tied with Texas, and better (when you mouse over each jurisdiction) than the results in each of the other states. Below, results for students with limited English proficiency are far lower, though our 64% rate is a bit better than the national 61%. Do give these powerful maps a close look: they'll make sure that the differences sink into your bones. (Added note: Consider a cautious viewing of the map for students with disabilities. It shows a 52% Kentucky graduation rate for students with disabilities, while Kentucky's school report card data file shows a 74% rate. The SRC 2012-13 file matches EdWeek for every other group, so there may be a data glitch somewhere. PrichBlog will try to find out why the numbers don't match and which statistics accurately reflect results for those students.).There have been developed internal combustion engines which are capable of mixing and combusting liquid fuel such as light oil, gasoline, etc., and compressed natural gas (hereinafter also referred to as CNG). For example, in Patent Document 1, there is disclosed an auxiliary fuel ignition type gas engine which uses light oil as auxiliary fuel. In this auxiliary fuel ignition type gas engine, mixed combustion of light oil and natural gas is carried out using the light oil as an ignition source. In addition, in Patent Document 1, there is described a technique in which at the time of light load, only light oil is supplied to the internal combustion engine, and at the time of medium load and high load, light oil and natural gas are supplied to the internal combustion engine. In Patent Document 2, there is disclosed a fuel injection control device which controls fuel injection into cylinders of an internal combustion engine. This fuel injection control device is provided with a reducing agent supply unit that supplies a reducing agent to an exhaust gas purification device. This reducing agent supply unit supplies the reducing agent to the exhaust gas purification device by performing, after main fuel injection, post injection as well as before-post injection small amount injection (pre injection) which is carried out before the post injection and which is smaller in the amount of injection than the post injection, by means of fuel injectors which serve to inject fuel into the cylinders, respectively. In Patent Document 3, there is disclosed that two or more of an oxygen concentration, a CO concentration and an HC concentration, of an exhaust gas are used as control parameters at the time when a reducing agent is supplied into an exhaust gas flowing into an exhaust gas purification device.New spy pictures of an undisguised 2017 Porsche 911 GT3 at the Nürburgring show that the car will get redesigned tail lights and a new rear bumper. The 2017 car will also get a revised front end, with more aggressive air intakes in the front bumper, a redesigned front spoiler, air intakes and new LED indicators, along

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253, 16851, 13765, 5837, 673, 14, 7527, 323, 436, 985, 310, 669, 3549, 5, 443, 6147, 15, 3824, 1783, 273, 436, 985, 4245, 253, 2363, 273, 436 ]

dotted lines showing the $\pm1\sigma$ isochrones. Finally the density of EXOFASTv2 samples is shown in the colour scale of the plotted posterior distribution.[]{data-label="fig:150_hr"}](150_hr){width="\columnwidth"} Figure \[fig:150\_hr\] includes a small collection of points above the main area of convergence. These data are not affected by increasing the run-time of the MCMC analysis or by increasing the burn-in period thus we do not believe them to be an artefact of unfinished fitting. However, since the significance of this region is $\lesssim$10 times lower than the peak we do not find it impactful. ### EXOFASTv2 analysis {#sec:EXOFASTv2 analysis} To perform simultaneous fitting of the SuperWASP detection, the SOPHIE RVs and the follow-up photometry we used the fitting code EXOFASTv2 [@Eastman2017; @Eastman2019]. This tool is designed to fit all the available data and ensure consistency between derived stellar and planetary parameters. EXOFASTv2 explores the given parameter space through a differential evolution Markov chain method using 30000 steps. We use the Gelman-Rubin statistic [@Gelman2003] to check the mixing of the chains as proposed by @Ford2006. We fit a total of 50 free parameters, these are the parameters presented in Table \[tab:MCMC parameters\] as well as limb darkening parameters for each band used and offset baselines and variances to account for any errors in normalisation. For the EXOFASTv2 input parameters we take period and epoch from the initial SuperWASP discovery photometry. Metallicity and effective temperature are taken from the results of spectroscopic analysis. Additionally, we use stellar radius and luminosity as well as parallax and distance from Gaia DR2. Finally we impose a prior on the V-band extinction from @Schlegel1998 and @Schlafly2011 which are used to model the stellar properties through SED fitting. Within EXOFASTv2 we use the MESA Isochrones and Stellar Tracks [MIST, @Dotter2016; @Choi2016] to model the star. This produces an age of $2.18^{+0.58}_{-0.65}$Gyr, which is in reasonable agreement with the [<span style="font-variant:small-caps;">bagemass</span>]{} age in Table \[tab:BAGEMASS properties\]. The best fit values, along with uncertainties, are presented in Table \[tab:MCMC parameters\]. WASP-176b --------- ### Stellar parameters {#sec:Stellar parameters 176} Similar to WASP-150, the stellar parameters of WASP-176 are calculated via a spectral analysis of the CORALIE spectra. The results of this analysis are shown in Table \[tab:Stellar parameters\]. Once again, the second data release of Gaia [@Gaia2016; @Gaia2018] provided some additional stellar parameters presented in Table \[tab:Gaia\]. Gaia was also searched for close companions of WASP-176. To determine the age of WASP-176 we again ran [<span style="font-variant:small-caps;">bagemass</span>]{} and show the results in Table \[tab:BAGEMASS properties\]. The best-fit evolutionary track and isochrone produced from the [<span style="font-variant:small-caps;">bagemass</span>]{} analysis are shown in Figure \[fig:176\_hr\] along with the $1\sigma$ uncertainties. This plot also includes the posterior distribution produced by the MCMC analysis (see section \[sec:MCMC analysis\]). ![[<span style="font-variant:small-caps;">bagemass</span>]{} analysis of WASP-176. The black line shows the Zero Age Main Sequence (ZAMS). The orange line shows the best fit mass track with the dotted lines showing the $\pm1\sigma$ mass tracks. The red line shows the isochrone relating to the best fit age with the dotted lines showing the $\pm1\sigma$ isochrones. Finally the density of MCMC samples is shown in the colour scale of the plotted posterior distribution.[]{data-label="fig:176_hr"}](176_hr){width="\columnwidth"} Once again we see that Figure \[fig:176\_hr\] includes a few points above the main peak. As before we find that these data are not affected by increasing the run-time of the MCMC analysis or by increasing the burn-in period so, again, we do not believe them to be an artefact of unconverged fitting. Since the significance of this region is $\sim$10 times lower than the peak we do not find it impactful. ### EXOFASTv2 analysis {#sec:MCMC analysis} As for WASP-150b we once again use EXOFASTv2 to derive the quoted parameters for WASP-176b. We use the same number of steps, 30000, and utilise the Gelman-Rubin statistic to check the mixing of the chains. We fit 43 free parameters, these are the parameters presented in Table \[tab:MCMC parameters\] as well as limb darkening parameters for each band used and offset baselines and variances to account for any errors in normalisation. In the same way as for WASP-150b we take the EXOFASTv2 input parameters from a combination of the WASP discovery photometry (period and epoch), spectroscopic analysis (metallicity and effective temperature) and Gaia DR2 (stellar radius, luminosity, parallax and distance). Additionally we impose a V-band extinction prior from @Schlegel1998 and @Schlafly2011. We use the MESA Isochrones and Stellar Tracks [MIST, @Dotter2016; @Choi2016] to model the star. This produces an age of $3.69^{+1.9}_{-0.83}$Gyr, which is in good agreement with the [<span style="font-variant:small-caps;">bagemass</span>]{} age in Table \[tab:BAGEMASS properties\]. The best fit values, along with uncertainties, are presented in Table \[tab:MCMC parameters\]. The WASP-176b analysis was first conducted allowing for an eccentric orbit. This resulted in $\chi^2_{ecc} = 11.423$ Repeating the analysis, this time forcing a circular orbit gives $\chi^2_{circ} = 11.358$. Since the discrepancy between these values is negligible it was decided there was insufficient evidence to support eccentricity and thus a circular orbit was assumed. Parameter (unit) WASP-150b WASP-176b ----------------------------------- ----------- ----------- $T_0$ (HJD) $P$ (days) $\Delta F$ $T_{14}$ (days) $b$ $i$ ($^{\circ}$) $e$ $M_\star$ ($\rm M_{\odot}$) $R_\star$ ($\rm R_{\odot}$) $\rho_\star$ ($\rm \rho_{\odot}$) $\log{g_\star}$ (cgs) $T_{eff}$ (K) $[Fe/H]$ $M_{pl}$ ($\rm M_J$) $R_{pl}$ ($\rm R_J$) $\rho_{pl}$ ($\rm \rho_J$) $\log{g_{pl}}$ (cgs) $T_{pl}$ (K) $a$ (AU) : System parameters from MCMC analysis[]{data-label="tab:MCMC parameters"} Discussion and conclusions {#sec:Discussion and conclusions} ========================== WASP-150b --------- WASP-150b is a high density hot Jupiter on a day orbit around its host. With a mass of of $\rm M_J$ and a radius of $\rm R_J$ WASP-150b has a density of $\rm \rho_J$ placing it amongst the highest density planets known. Figure \[fig:density plot\] shows a plot of all the confirmed exoplanets from the NASA exoplanet archive with radius and mass known to an accuracy of $\leq$ 10% and periods of $\leq$ 10 days. Though large, this density is in line with expectations based on the planets mass [@2009AIPC.1094..102C]. ![Scatter plot of all confirmed exoplanets from the NASA exoplanet archive with radius and mass known to an accuracy of $\leq$ 10% and periods of $\leq$ 10 days. The points are then coloured by density in cgs units. WASP-150b is shown as a red diamond and Jupiter is shown as a black diamond for reference (WASP-176b is shown as an orange diamond). The plot also includes lines of constant density to guide the eye.[]{data-label="fig:density plot"}](density){width="\columnwidth"} WASP-150b is also relatively eccentric ($e$ = ). Using equation (3) from @Adams2006 (and assuming $Q_p \sim 10^5$) we see that the approximate circularisation time-scale for this system is $\sim$ Gyr. Our analysis of this system gives the age of this

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1705, 588 ]

July 13. MAGNETISM. /■'roetic/i's Magnetic Lau'. — \\\ an article by Dr. Froelich, in the "Elek. Zeit.," July 5, he calls attention to the law which he recently deduced (see Digest, Aug. 12. 1893, also Feb. 17, and The Electrical World, Feb. 24, p. 23'*), stating that he has since endeavored to verify it by experiments, obtaining good results, but finding that the calculated maximum flux was always smaller than that which had been found experimentally with high magnetizing forces. He concludes that the apparatus with which such measurements are usually made involves a number of errors when liii-h magnetizing forces are used; he refers to those usually used in practice in which the iron is surrounded by a coil, its circuit being com- pleted by an iron yoke; among them are: that the influence of the yoke, as also that of the contact surface, is not eliniinaled with sufficient pre- cision; that the magnetizing coil has an action not only on the sample but also on the yoke, which action was not taken into account with sufficient inecision; that the small test coil is affected not only by the llux through the iion sample; but also by that in the yoke and in the air space, and finally that the sharp ends in the iron give rise to leakage at high magnetization. In order, therefore, to test his formulas, he calculates a seiies of results and curves from the recent researches of Mr. Lehman, published in "Wied. Ann.," vol. 48, page 405, in which the method of KirchholT was used, which is free from the above named errors, and which, it may be safely assumed, gives the true magnetization curve; in tiiis method a complete iron ring surrounded by tie coil was used. Dr. I'loclich gives his formulas, the deduced values of the con.stants and seveial tables of results and curves, showing the dilTerence between the calculated and observed values, the agreement being a very satisfactoiy one ; the above refers to his more complicated but nu)re accurate formu- las, and he therefore concludes that these formulas repiescnt the true magnetizing law of iron; he finds from these results that the maximum llux is very much higher than was usually supposed, and furthermore, tliat it cannot be determined with any accuracy. He also applies his simpler aijproximate formulas to these results and finds that they are veiy reliable for magnetizing forces between H = (> and 11=40 — that is, f<ir the lange used in practice— but that above and below these values they do not apply (it will be remembered that this was a straight line law) ; he concludes, therefore, that his simple formulas can safely be applied in practice, but that the value of the ina.xinuim flux which enters in them is not the true maximum, but is only an apparent one, and therefore has the character of a mathematical constant. UNITS, MEASUREMENTS AND INSTRUMENTS. The Arc as a.S'/anrfarrf.— See abstract under "Rotation of the Electric Arc" .Specific Resistance of Pure Copper. — A Royal Society paper by Messrs. Swan and Rliodin is abstracted in the Lond. "Elec," July 13. Great care was taken to obtain the purest electrolytic copper, only the best of a large niiraber of samples being used and again refined electrolytically : the di- ameters were determined by the specific gravity method ; the absolute spe- cific resistance at 0° C. was calculated from the temperature co-efficients which were carefully determined; the density was 8.9587 at 15° C. ; the specific resistance in C. G. S. unitstpresumably at 0° C, although not so stated) for one sample was 1,603 hard.as drawn, 1,566 for the same sample annealed and 1,559 for another sample annealed; the temperature co-effi- cients were respectively 0.00408. 0.00418, 0.00415; he believes that the mean is the probable correct value, and gives the following as the true values; hard 1,603. soft 1,563; temperature co-efficients 0.00408 and 0.0041(> respectively. (Attention is called by the compiler to the determinations of Mr. Lagarde, given in the Digest, Oct. 7, 1893. further references to the original being given in the Digest, Nov. 18, 1893, and March 17, 1894.) Magnetic Curve Tracer. ^Kccoxi\n% to an editorial in the Lond. "Elec," July 13, Mr. Hess, before the French Academy, proposes to make use of the peculiarities of cathode rays pointed out by Dr. Lenard for obtaining a curve tracer with a pointer without inertia ; cathode rays are made to fall "on a rapidly moving photographic film, the whole "observing space," as Dr. Lenard calls it, being placed within the vari- able electric field to be investigated. Measuring Co-efficients of Induction. — An Academy paper by Mr. Abra- ham, on the measurements and comparison of true co-efficients of induc- tion by alternating currents of high frequency, is abstracted in "L'Ind. Elec," July 10, and more fully in "L'Elec." July 7; a Wheatstoue bridge and telephone are used ; the formulas for the relations are given. Measuring the Efficiency of a Large Motor. — The article by Mr. Rey. mentioned in the Digest last week, is given in abstract in "L'Ind. Elec," July 10 Meter.— The Brocq meter is described and illustrated in "La Lum. Elec," July 7; a solenoid operates a float in a sort of dashpot, the motion of which is registered. TRANSFORMERS. Transformer System. — Mr. Whitcher. in the Lond. "Elec. Rev.," July 13, states that his method (see Digest July 28) is not as described in that journal ; he does not, however, describe it clearly. He states that an extra primary main is used in place of an automatic switch, on the primary side as well as on the secondary, and that he disperses with all automatic mechanism, using only the same number of mains: for large sub-stations he proposes to use a method in which the currents in the two sides of the three-wire system can be varied in phase relatively to each other, from consonance through all values of nppositeness, by means of which the engineer at the central station can control the transformer capacity by the suitable alteration of the phase dilTerence ; he also speaks of controlling it by varying the induction in some of the transformers. Constant Current Transjormer System. — In a description of the Fer- ranti system in "L'Elec," July 7 (see Digest. June -W, under "Ports- mouth"). Mr. Meylan adds a theory of the action of such transformers, showiue that it is questionable whether one can, by this means, obtain a true automatic regulator of the current and concludes that the construc- tion depends on the limits between which regulation is to be effected. Current Ruslies in Tran.'forniers. — Mr. Hay's article is continued in the Lond. "Elec," July 13; he discusses the effect of frequency and finds that the current rushes increase with the periodicity (that is, fie- quency). He then discusses experiments with inductive circuits con taining iron and gives curves and tables; in a certain case the curient rush was 6.74. In the same issue he replies to the comments of Dr. F'leming mentioned in the Digest last week, in which he states th,at the fact that his remarks applied to circuits without iron seems to have been overlooked by that Clitic and hopes th.at his statements will have the effect of shaking the confidence in some of Dr. FMeming's conclusions. AFC AND INCANDE.SCENT LIGHTS. Trojectors.— The "Elek. Zeit.." June 5, contains.an article of some length by Mr. Nerz. He discusses at some length the various statements made in the discussion of the.subject of photometry of projectors, which was published in The Electiical World last year; regarding Prof. S. P. Thompson's statement, he showed that according to that writer one square millimetre of crater has an intensity of 11.1 candles, while the present writer has obtained a maximum value more than ten times as great ; he shows that with the large Schuckeit search light at Chicago, on the assumption that the beam has an angle of 2 degrees, the theoretical point August 4, 1894. THE ELECXRICAIv WORLD. 109 from which the light appears to come will

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private const string CodeActionMetadataName = "Microsoft.CodeAnalysis.CodeActions.CodeAction"; private static readonly ImmutableArray<string> s_WorkspaceAssemblyNames = ImmutableArray.Create( "Microsoft.CodeAnalysis.Workspaces", "Microsoft.CodeAnalysis.CSharp.Workspaces", "Microsoft.CodeAnalysis.VisualBasic.Workspaces"); public static readonly DiagnosticDescriptor DoNotUseTypesFromAssemblyDirectRule = new DiagnosticDescriptor( DiagnosticIds.DoNotUseTypesFromAssemblyRuleId, s_localizableTitle, s_localizableMessage, DiagnosticCategory.MicrosoftCodeAnalysisCorrectness, DiagnosticSeverity.Warning, isEnabledByDefault: true, description: s_localizableDescription, customTags: WellKnownDiagnosticTags.Telemetry); public static readonly DiagnosticDescriptor DoNotUseTypesFromAssemblyIndirectRule = new DiagnosticDescriptor( DiagnosticIds.DoNotUseTypesFromAssemblyRuleId, s_localizableTitle, s_localizableIndirectMessage, DiagnosticCategory.MicrosoftCodeAnalysisCorrectness, DiagnosticSeverity.Warning, isEnabledByDefault: true, description: s_localizableDescription, customTags: WellKnownDiagnosticTags.Telemetry); protected abstract bool IsNamedTypeDeclarationBlock(SyntaxNode syntax); public override ImmutableArray<DiagnosticDescriptor> SupportedDiagnostics => ImmutableArray.Create(DoNotUseTypesFromAssemblyDirectRule, DoNotUseTypesFromAssemblyIndirectRule); public override void Initialize(AnalysisContext context) { context.EnableConcurrentExecution(); context.ConfigureGeneratedCodeAnalysis(GeneratedCodeAnalysisFlags.Analyze); context.RegisterCompilationStartAction(compilationStartContext => { if (compilationStartContext.Compilation.GetOrCreateTypeByMetadataName(CodeActionMetadataName) == null) { // No reference to core Workspaces assembly. return; } INamedTypeSymbol? diagnosticAnalyzer = compilationStartContext.Compilation.GetOrCreateTypeByMetadataName(WellKnownTypeNames.MicrosoftCodeAnalysisDiagnosticsDiagnosticAnalyzer); if (diagnosticAnalyzer == null) { // Does not contain any diagnostic analyzers. return; } var hasAccessToTypeFromWorkspaceAssemblies = false; var namedTypesToAccessedTypesMap = new ConcurrentDictionary<INamedTypeSymbol, ImmutableHashSet<INamedTypeSymbol>>(); var diagnosticAnalyzerTypes = new ConcurrentBag<INamedTypeSymbol>(); compilationStartContext.RegisterSymbolAction(symbolContext => { var namedType = (INamedTypeSymbol)symbolContext.Symbol; if (namedType.DerivesFrom(diagnosticAnalyzer, baseTypesOnly: true)) { diagnosticAnalyzerTypes.Add(namedType); } var usedTypes = GetUsedNamedTypes(namedType, symbolContext.Compilation, symbolContext.CancellationToken, ref hasAccessToTypeFromWorkspaceAssemblies); var added = namedTypesToAccessedTypesMap.TryAdd(namedType, usedTypes); Debug.Assert(added); }, SymbolKind.NamedType); compilationStartContext.RegisterCompilationEndAction(compilationEndContext => { if (diagnosticAnalyzerTypes.IsEmpty ||!hasAccessToTypeFromWorkspaceAssemblies) { return; } var typesToProcess = new Queue<INamedTypeSymbol>(); var processedTypes = new HashSet<INamedTypeSymbol>(); var violatingTypeNamesBuilder = new SortedSet<string>(); var violatingUsedTypeNamesBuilder = new SortedSet<string>(); foreach (INamedTypeSymbol declaredType in namedTypesToAccessedTypesMap.Keys) { if (!diagnosticAnalyzerTypes.Contains(declaredType)) { continue; } typesToProcess.Clear(); processedTypes.Clear(); violatingTypeNamesBuilder.Clear(); violatingUsedTypeNamesBuilder.Clear(); typesToProcess.Enqueue(declaredType); do { var typeToProcess = typesToProcess.Dequeue(); Debug.Assert(typeToProcess.ContainingAssembly.Equals(declaredType.ContainingAssembly)); Debug.Assert(namedTypesToAccessedTypesMap.ContainsKey(typeToProcess)); foreach (INamedTypeSymbol usedType in namedTypesToAccessedTypesMap[typeToProcess]) { if (usedType.ContainingAssembly!= null && s_WorkspaceAssemblyNames.Contains(usedType.ContainingAssembly.Name)) { violatingTypeNamesBuilder.Add(usedType.ToDisplayString()); violatingUsedTypeNamesBuilder.Add(typeToProcess.ToDisplayString()); } if (!processedTypes.Contains(usedType) && namedTypesToAccessedTypesMap.ContainsKey(usedType)) { typesToProcess.Enqueue(usedType); } } processedTypes.Add(typeToProcess); } while (typesToProcess.Count!= 0); if (violatingTypeNamesBuilder.Count > 0) { string[] args; DiagnosticDescriptor rule; if (violatingUsedTypeNamesBuilder.Count == 1 && violatingUsedTypeNamesBuilder.Single() == declaredType.ToDisplayString()) { // Change diagnostic analyzer type '{0}' to remove all direct accesses to type(s) '{1}' rule = DoNotUseTypesFromAssemblyDirectRule; args = new[] { declaredType.ToDisplayString(SymbolDisplayFormat.MinimallyQualifiedFormat), string.Join(", ", violatingTypeNamesBuilder) }; } else { // Change diagnostic analyzer type '{0}' to remove all direct and/or indirect accesses to type(s) '{1}', which access type(s) '{2}' rule = DoNotUseTypesFromAssemblyIndirectRule; args = new[] { declaredType.ToDisplayString(SymbolDisplayFormat.MinimallyQualifiedFormat), string.Join(", ", violatingUsedTypeNamesBuilder), string.Join(", ", violatingTypeNamesBuilder) }; } Diagnostic diagnostic = declaredType.CreateDiagnostic(rule, args); compilationEndContext.ReportDiagnostic(diagnostic); } } }); }); } private ImmutableHashSet<INamedTypeSymbol> GetUsedNamedTypes(INamedTypeSymbol namedType, Compilation compilation, CancellationToken cancellationToken, ref bool hasAccessToTypeFromWorkspaceAssemblies) { var builder = PooledHashSet<INamedTypeSymbol>.GetInstance(); foreach (var decl in namedType.DeclaringSyntaxReferences) { var syntax = decl.GetSyntax(cancellationToken); // GetSyntax for VB returns the StatementSyntax instead of BlockSyntax node. syntax = syntax.FirstAncestorOrSelf<SyntaxNode>(node => IsNamedTypeDeclarationBlock(node), ascendOutOfTrivia: false)?? syntax; #pragma warning disable RS1030 // Do not invoke Compilation.GetSemanticModel() method within a diagnostic analyzer var semanticModel = compilation.GetSemanticModel(syntax.SyntaxTree); #pragma warning restore RS1030 // Do not invoke Compilation.GetSemanticModel() method within a diagnostic analyzer var nodesToProcess = new Queue<(SyntaxNode node, bool inExecutableCode)>(); nodesToProcess.Enqueue((node: syntax, inExecutableCode: false)); do { (SyntaxNode node, bool inExecutableCode) nodeToProcess = nodesToProcess.Dequeue(); var node = nodeToProcess.node; var inExecutableCode = nodeToProcess.inExecutableCode; if (!inExecutableCode &&!ReferenceEquals(node, syntax) && IsNamedTypeDeclarationBlock(node)) { // Skip type member declarations. continue; } if (node is TTypeSyntax typeSyntax) { var typeInfo = semanticModel.GetTypeInfo(typeSyntax, cancellationToken); AddUsedNamedTypeCore(typeInfo.Type, builder, ref hasAccessToTypeFromWorkspaceAssemblies); } if (!inExecutableCode) { var operationBlock = semanticModel.GetOperation(node, cancellationToken); if (operationBlock!= null)

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Mr. Bill Veeck of the White Sox, to go up to the plate and get a walk because his strike zone was so small." "Back to the graveyard, please." "That's all, your honor. Ms. Caine told me I needed to be a witness." The judge looked at me. "A witness of what, Ms. Caine?" Stupid judge. He'd taken the legs out of the testimony. I'd have to prop it back up. "If I may continue to question my own witness?" I said. "Don't take that tone with the court," the judge said. Manyon sat back with a half smile on his face. I said to Leon, "You saw a figure before I took you down, isn't that true?" "Yes. Sandy." "Only it couldn't have been, because he was too young?" "Well, yes." "Did this figure change shape as far as you know?" "Objection, your honor," said Manyon. "Assumes a fact not in evidence. The witness just said he thought it was Sandy Koufax. That's all. We have no evidence of something changing shape, whatever that is supposed to mean." "Agreed," said the judge. "You will have to rephrase your question, Ms. Caine." "What did you see after you got up from the ground?" I asked. "Well now, I thought I saw something fuzzy with long nails. Not that I was shocked. My ex-wife looked the same way—" "Your honor, if you please," Manyon said. "Just answer the questions without your color commentary," the judge said. "I'm tryin' to, Judge, it's just the way I have of speakin'." Judge Blankenship rubbed his eyes. "What about the nails?" I asked. "Long. Really long. I wouldn't want to be scratched by those things... Sorry, judge, that's the way I feel." "Go on," Blankenship said to me. "Anything else?" I asked. "The eyes," Jones said. "She had terrible eyes." "Object to the word she," Manyon said. "Sustained." "What do you mean by terrible?" I said. "Mean. Deadly. Like Bob Gibson." "Who?" "A pitcher you never would want to face, I can tell you. He'd—" "Mr. Jones," the judge said, "that will do." "May we approach the bench, your honor?" Manyon said. Up to the bench we went. Manyon said, "Your honor, the testimony of this witness is irrelevant and immaterial. There has been no proof offered that whatever this man thinks he saw on some given night is the boy's mother. This testimony has nothing to do with custody and everything to do with Ms. Caine trying desperately to cloud the issues." "I have to agree," the judge said. "Unless you can provide a connection to the boy's mother, Mr. Jones's testimony is not germane to these proceedings. Can you provide such proof?" Fake it till you make it. "Yes, your honor. If I can call an expert witness." "Is he here?" "In a way." "What's that mean?" "You can't see him yet. He'll manifest himself." "Ms. Caine, if you—" "Let me bring him in." "Then do it. Mr. Jones will step down, subject to recall. But until you provide a foundation for his testimony, I will not consider it in the slightest." CHAPTER 34 "Cool Train" Jones looked disappointed as he left the stand. I'm sure he had more baseball stories to tell. Then I said, "I call Darren McGavin." Eyes turned toward the courtroom gallery. Darren McGavin, dressed as I had first seen him, came forward. Until that point he had been invisible. He'd told me he preferred it that way. No need to cause a fuss, he'd said. Some people still remembered Kolchak. However, it did look like he popped out of nowhere. "What... just happened there?" the judge said. "Mr. McGavin is ready to be sworn," I said. "I mean, I mean. I don't know what I mean. I thought I saw. Never mind. Swear the witness." "One moment," Charles Beaumont Manyon said. "I believe I can help your honor with the confusion." "That'll be the day," I said. Without any warning, Manyon picked up a copy of the evidence code from his counsel table, walked over to Darren McGavin, and tossed it at him. The book passed completely through the ghost and thudded to the floor. The people in the gallery gasped. One woman screamed. The poor bailiff looked like he didn't know what to do. "This is a specter," Manyon said. "A ghost. A dead person. Dead people cannot testify in court." "And where does it say that?" I asked. "There is no provision against dead people testifying. The test is competence, and Mr. McGavin is certainly competent to testify. I would remind Mr. Manyon that a witness is presumed competent under the evidence code itself "—I dramatically picked up the tome from the floor and held it aloft—"unless there has been some showing of an inability on the part of the witness to perceive, remember, communicate, or appreciate the oath. Mr. McGavin, despite being a ghost, meets all the tests." Blankenship's lips were moving. Little spitballs were forming at the corners of his mouth. His eyes shifted back and forth as if on involuntary status. "Somebody get the judge a glass of water," I said. His clerk, a lovely but confused young woman, attended to the water. Manyon glowered at me. I don't take to the glower. We all waited for the judge to gather himself. When he finally looked up, he said, "I'm not going to make my decision yet. I will hear the testimony and then decide." "But your honor," Manyon said. "Who is the judge around here? Swear him in and let's get on with it!" "Mr. McGavin, you were an actor, is that correct?" "Yes, I was. Loved it. It was fun." "You performed on stage, screen, and television?" "That's right." "You appeared on a series called Kolchak: the Night Stalker, is that right?" The court reporter asked me to spell it, so I did. "That's right," Darren McGavin's ghost said. "It appeared on the ABC network, for one season in the 1970s. Should have run longer." "But the series has caught on with new fans, is that right?" "Wonderful things, the DVDs, the Netflix deal. Wish we'd had 'em back when I was doing the show." "What was the premise of this series, Mr. McGavin?" "Well, Carl Kolchak, he was a newspaper crime reporter, you see, and he would investigate these stories and find out there was something strange going on each time. A different sort of supernatural explanation for things. You know, vampires, werewolves, and the like. We got into some of the more obscure monsters, like the Indian bear spirit. And so on." "And the Rakshasa?" "Yes, that was one of our more popular episodes. The Hindu demon." "Now, Mr. McGavin, during the course of these episodes did you do any of your own research into the substance of the show?" "Yes, I did. I took a great interest in each of them." "Will you please tell the court what you discovered about the Rakshasa." "Certainly." He turned toward the judge, whose ashen face was frozen in a state of imperial unbelief. "Well, your honor, it seems these Rakshasas are very ugly in their native form, with long nails and flesh-eating tendencies. They are the souls of extremely wicked people. Being a Rakshasa requires something more than just normal, everyday evil. You have to be like a Genghis Khan or a Nero." "Now," I said, "what can a Rakshasa do to confuse us?" "They can appear to you to be someone you absolutely trust. They can go into your mind and take out a picture of that person and become that person in your eyes. They use this ploy to get you to approach them, you see, until they can reach out and kill you." "So, hypothetically speaking, if someone had been a professional baseball player, would the Rakshasa be able to appear to him as a former teammate?" "Quite easily." Manyon stood up. "Your honor, we've had quite enough of this. There is no relevance here, no foundation for these questions. If Ms.

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a local martingale. And we conclude by the uniqueness of the martingale problem associated to $D$. $\square$ Let us note eventually that when $2k$ equals the multiplicity associated with a Riemannian symmetric space of noncompact type $G/K$, then the radial HO-process coincide with the radial part of the Brownian motion on this symmetric space (see [@HO], or [@Schap]). For instance if $G=SL_n$, then $k=\frac{1}{2}$ in the real case, $k=1$ in the complex case, and $k=2$ in the quaternionic case. So most of our results about radial processes generalize known results of the probabilistic theory on symmetric spaces. The Dunkl processes {#definitiondunkl} ------------------- We recall now the definition of the Dunkl process and of its radial part. Let ${\mathcal{R}}'$ be a reduced root system (i.e. such that $\forall \alpha \in {\mathcal{R}}'$, $2\alpha \notin {\mathcal{R}}'$), but non necessarily integral (i.e. we do not assume condition $3$ in the definition), and let $k'$ be a multiplicity function on ${\mathcal{R}}'$. The Dunkl Laplacian ${\mathcal{L}}'$ is defined for $f\in C^2({\mathfrak{a}})$, and $x\in {\mathfrak{a}}_{\text{reg}}$ by $$\begin{aligned} {\mathcal{L}}' f(x)&=& \frac{1}{2}\Delta f(x)+ \sum_{\alpha \in {\mathcal{R}}'^+}k'_\alpha \frac{1}{(\alpha,x)}\partial_\alpha f(x) \\ &+& \sum_{\alpha \in {\mathcal{R}}'^+}k'_\alpha \frac{1}{(\alpha,x)^2}\{f(r_\alpha x)-f(x)\}.\end{aligned}$$ It was proved by Rösler in [@Ros] that ${\mathcal{L}}'$ defined on ${\mathcal{S}}({\mathfrak{a}})$, the classical Schwartz space on ${\mathfrak{a}}$, is a closable operator, which generates a Feller semigroup on $C_0({\mathfrak{a}})$. Naturally the Dunkl process is the Feller process defined by this semigroup. Now our proof (in [@Schap]) that the operator $D$ defined on ${\mathcal{C}}({\mathfrak{a}})^W$ is closable, also holds in the Dunkl setting. Thus we may define the radial Dunkl process as the Feller process on $\overline{{\mathfrak{a}}_+}$ with generator the closure of $(L',{\mathcal{S}}({\mathfrak{a}})^W)$, where $L'$ is the differential part of ${\mathcal{L}}'$, and ${\mathcal{S}}({\mathfrak{a}})^W$ is the subspace of ${\mathcal{S}}({\mathfrak{a}})$ of $W$-invariant function (identified with their restriction to $\overline{{\mathfrak{a}}_+}$). In this way we get a new characterization of the radial Dunkl process as solution of a martingale problem. Naturally Proposition \[premiereprop\] holds as well in the Dunkl setting, thus our definition of the radial Dunkl process agrees with the usual one. Eventually the intrinsic Brownian motion is by definition the radial Dunkl process of parameter $k'=1$. The radial HO-process as a Dirichlet process ============================================ The goal of this section is to obtain an explicit semimartingale decomposition of the radial HO-process. In the case of root systems of type $A$, it was obtained by Cépa and Lépingle (see [@Cep] and [@CepLep2] Theorem $2.2$). We present here another approach, which is based on the theory of Dirichlet processes. Our reference for this theory will be [@FukOT]. We consider $(D,{\mathcal{C}}({\mathfrak{a}})^W)$ as a symmetric operator on $L^2(\overline{{\mathfrak{a}}_+},\mu)$ (simply denoted by $L^2$ in the sequel). We have seen in [@Schap] that this operator is closable. We denote by $(D,{\mathcal{D}}_2(D))$ its closure. Its associated semigroup is just the extension of $(P_t^W,t\ge 0)$ on $L^2$. It is defined for $f,g\in L^2$ and $t\ge 0$ by $$P_t^Wf(x)= \int_{\overline{{\mathfrak{a}}_+}}p_t^W(x,y)f(y)d\mu(y).$$ We denote by ${\mathcal{E}}$ the associated Dirichlet form, and by ${\mathcal{F}}$ its domain (${\mathcal{D}}_2(D)\subset {\mathcal{F}}$). It is determined for $f,g \in {\mathcal{D}}_2(D)$ by $${\mathcal{E}}(f,g):=-\int_{\overline{{\mathfrak{a}}_+}}f(x)Dg(x)d\mu(x)=-\int_{\overline{{\mathfrak{a}}_+}}Df(x)g(x)d\mu(x).$$ The fact that ${\mathcal{E}}$ is a regular Dirichlet form with special standard core the algebra ${\mathcal{C}}({\mathfrak{a}})^W$, results from the density of this space in $C_0(\overline{{\mathfrak{a}}_+})$ (see Lemma $5.1$ in [@Schap]) and Theorem $3.1.2$ in [@FukOT]. We have seen in [@Schap] that when $f\in L^1({\mathfrak{a}},\mu)$, then $Gf:x \mapsto \int_0^\infty P_t^Wf(x)dt$ is a.e. finite. In the terminology of [@FukOT], this means that the Dirichlet form ${\mathcal{E}}$ (or the semigroup $P_t^W$) is transient. This implies in particular that the process tends to infinity when $t\to \infty$. In the sequel we will prove a law of large numbers which makes this fact precise. It implies also that we may consider ${\mathcal{F}}$, equipped with its inner product ${\mathcal{E}}$, as a Hilbert space (see [@FukOT] chapter $2$). For $i=1,\dots,n$, we denote by $\varphi_i :x\mapsto x_i$ the coordinate functions on $\overline{{\mathfrak{a}}_+}$. For $A>0$, let $\varphi_i^A \in C^\infty(\overline{{\mathfrak{a}}_+})$ be a function which coincides with $\varphi_i$ on $\{|x|\le A\}$, and which is null on $\{|x|\ge A+1\}$. For all $A >0$, $\varphi_i^A \in {\mathcal{F}}$, and for all $v\in {\mathcal{C}}({\mathfrak{a}})^W$, $${\mathcal{E}}(\varphi_i^A,v)=-\int_{\overline{{\mathfrak{a}}_+}}D\varphi_i^A vd\mu.$$ **Proof of the lemma:** Let $(u_n)_n\in {\mathcal{C}}({\mathfrak{a}})^W$ which converges uniformly to $\varphi_i^A$ as in Lemma $5.1$ in [@Schap]. We will assume that $|u_n-\varphi_i^A|_\infty \le \frac{1}{n}$ for all $n$. We have to prove that it is an ${\mathcal{E}}$-Cauchy sequence. Let $n<m$ be two integers. We have $$\begin{aligned} {\mathcal{E}}(u_n-u_m,u_n-u_m) &=& \int_{d(x,\partial {\mathfrak{a}}_+)\le \frac{1}{m}}D(u_n-u_m)(u_n-u_m)d\mu \\ &+& \int_{\frac{1}{m}\le d(x,\partial {\mathfrak{a}}_+)\le \frac{1}{n}} D(u_n-u_m)(u_n-u_m)d\mu \\ &+& \int_{d(x,\partial {\mathfrak{a}}_+)\ge \frac{1}{n}}D(u_n-u_m)(u_n-u_m)d\mu.\end{aligned}$$ By Lemma $5.1$ in [@Schap], the integrand in the first integral is bounded, up to a constant, by $\frac{m}{n}$. But $\mu(\{d(x,\partial {\mathfrak{a}}_+)\le \frac{1}{m}, |x|\le A+1\})$ is bounded, up to a constant, by $\frac{1}{m}$. Thus the first integral tends to $0$ when $n\to \infty$. The same argument applies for the second integral. The third integral is naturally bounded, up to a constant, by $\frac{1}{n}$. Now always by Lemma $5.1$ in [@Schap], the sequence $(D u_n)_n$ is dominated, up to a constant, by $x\mapsto \frac{1}{d(x,\partial {\mathfrak{a}}_+)}+\sum_\alpha \coth \frac{\alpha}{2}$ on $|x|\le A

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n3311106.md.png'/></a> <br/> 原文地址（需翻墙访问）：http://www.soundofhope.org/gb/2019/11/04/n3311106.html ------------------------ #### [首页](https://github.com/gfw-breaker/banned-news/blob/master/README.md)  |  [一键翻墙软件](https://github.com/gfw-breaker/nogfw/blob/master/README.md)  | [《九评共产党》](https://github.com/gfw-breaker/9ping.md/blob/master/README.md#九评之一评共产党是什么) | [《解体党文化》](https://github.com/gfw-breaker/jtdwh.md/blob/master/README.md) | [《共产主义的终极目的》](https://github.com/gfw-breaker/gczydzjmd.md/blob/master/README.md) <img src='http://gfw-breaker.win/banned-news/pages/soh_zgxw/n3311106.md' width='0px' height='0px'/>Inverkeithing railway station Inverkeithing railway station serves the town of Inverkeithing in Fife, Scotland. The station is managed by Abellio ScotRail and is on the Fife Circle Line, north west of. The station is popular with commuters travelling to Edinburgh from Fife and beyond, thanks to its location beside the M90 motorway. Immediately north of the station, the Fife Circle Line splits in two - the main line continuing along the coast via whilst the branch heads inland towards Dunfermline. History It opened in 1877, at the same time as the tracks of the Dunfermline and Queensferry Railway. Facilities Two large free of charge park and ride car parks are provided. The station is currently staffed for all trains and has public toilets, and a ticket hall. There is also a waiting room and a wheelchair accessible footbridge. Services Journey times as low as 15 minutes are available to as CrossCountry, London North Eastern Railway and Abellio ScotRail express services between Edinburgh and stop here. Some services between Edinburgh and also stop at Inverkeithing. Mondays to Saturdays daytimes, four Fife Circle Line trains per hour go southbound to Edinburgh. Northbound, services run every half-hour to, and half-hourly to. One of the former & both of the latter continue to. Evenings and Sundays, two trains per hour go southbound to Edinburgh and two per hour go along the Fife Circle one in each direction (one via Dunfermline and one via Kirkcaldy). Monday to Saturday - most daytime ScotRail services to Aberdeen and Inverness no longer stop here (though a few calls are made to both destinations in the early morning & evening). The primary longer distance service is provided by half-hourly semi-fast trains from Edinburgh to either Perth or Dundee (hourly to each), which serve most stations north of Kirkcaldy. There is a once daily train to via Winchburgh Junction and each morning, returning in the evening peak. On Sundays, there is a limited service to Perth & Inverness and a mostly hourly service to Dundee & Aberdeen. London North Eastern Railway services between Aberdeen, London King's Cross and Leeds call at Inverkeithing, as do CrossCountry services between Aberdeen or Dundee and Plymouth/Penzance. References External links Bus service to Edinburgh Airport Video footage of Inverkeithing railway station Category:Railway stations in Fife Category:Former North British Railway stations Category:Railway stations opened in 1877 Category:Railway stations served by Abellio ScotRail Category:Railway stations served by Caledonian Sleeper Category:Railway stations served by CrossCountry Category:Railway stations served by London North Eastern Railway Category:1877 establishments in ScotlandQ: How to redefine the names for the standard keywords in C# I have the interesting idea. I want to redefine the keywords in C#, like replace the if keyword to the MyIf or something else. Do someone have any idea about how to do it? As I think it have to look something like this: namespace { #define MyIf = if; #define MyElse = else; ... public someclass { public void someMethod() { MyIf(true) { ... } MyElse { ... } } } } Added: Maybe there is the way how to make the C++ or C library which will redefine the part of standard core of C#? **Notice. I know that it is the bad programming practice and I ask all the programmers to not use the answer in your enterprise code. ** A: That's not possible -- C# does not have a preprocessor like C and C++ do, so there is no mechanism to transform the source before the compiler sees it. And of course the compiler will only recognize the standard if, so there is also no other option that somehow transforming the source before the compiler sees it. Even if it were possible, it would be just a step below Cthulhu in the horror scale. A: In c# you can override the overloadable operators (+, -, ==) more info here: http://msdn.microsoft.com/en-us/library/8edha89s(v=vs.80).aspx But you can't really override conditional operators. The same goes for these operators =,.,?:, ->, new, is, sizeof, typeof, they cannot be overloaded. C# does not support macros, but of course you could write a custom parser that handles macros before eventually sending your code to the c# compiler, take a look at Microsoft Roslyn for that. http://msdn.microsoft.com/en-us/vstudio/roslyn.aspx Is It Better to Save or to Spend? Restricted as this page usually is to questions (and answers), its posts can, I realize, seem more than a bit off the news. This is especially true when the economic world is roiling, as it so often has been of late. So let today’s post be a meditation on the roil and in particular, the center-stage question facing the U.S. and Europe, one that has prompted occasionally heated exchanges on my Twitter. The quandary is obvious: stimulus or austerity? In economic jargon, Keynesian or the Austrian School? In plainer terms, save or spend? But which is the right answer? Each side is championed these days, as it was in the last Great Downturn, by Democrats on the one hand, and Republicans on the other — and abroad, by their political equivalents. This cartoon from the conservative Chicago Tribune in 1934 illustrates the Republican point of view in reaction to the spending of the New Deal. Obama a “socialist”? Note that the Roosevelt administration (in the runaway wagon) is supposedly “communist”, following the script of the man at the lower left. That’s Leon Trotsky, once a leader of the Soviet Union and its Red Army. By 1934, he had long since been exiled by Stalin and was living in France, but the symbolic value of his image apparently remained vivid enough for the average American. (Or maybe the Trib hadn’t kept up with times.) Caricature assassination aside, the essence of New Deal Keynesian spending is simple and seemingly sensible: that there’s nothing worse than idle resources and the very worst resource to idle are human beings, for reasons both political and economic. The political cost of idle hands is screamingly obvious: an unemployed, disaffected, meaner citizenry. (See Benjamin Friedman’s major book of 2005, “The Moral Consequences of Economic Growth,” for the damages of contraction. Or glance at Germany after the Great Depression of the early ’30s.) When citizens lose their jobs, they can’t afford to keep spending. When consumer spending stalls, businesses see no reason to make new investments — “Who will buy?”, the song from “Oliver!”, springs to the mind’s ear. Businesses slow their spending, too. The quick fix for this problem — for decades — has been lowering short-term interest rates to make borrowing cheaper and thus kick start spending. But it doesn’t work if interest rates are at zero, as they are now. You can’t have a negative interest rate. Unless you give people money, that is. And that’s the argument for stimulus. Absent the consumer and business, there’s only one Big Spender left, argue the Keynesian Democrats: government, the spender of last resort. It can give people money by

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~O~2~ in methanol at room temperature for 20 min to inactivate the endogenous peroxidases, after which the cells were washed thrice with PBS. (3) The cells were incubated with 2 *μ*L of TdT-enzyme and 48 *μ*L of Biotin-dUTP per specimen for 60 min at 37°C. The cells were terminated for 10 min, and were consequently incubated with streptavidin-HRP (50 *μ*L per specimen) conjugate diluted at 1:50 in sample diluent for 30 min. (4) The cells were washed three times with PBS, and were consequently incubated with diaminobenzidine solution (200 *μ*L per specimen) for 10 min. At last, the cells were rewashed twice with PBS, and were consequently imaged under an XDS-1B inverted biological microscope \[[@B30]\]. Flow cytometry analysis ----------------------- Prepared MGC-803 cells (1×10^6^/mL) were washed twice with cold PBS and then re-suspended gently in 500 *μ*L binding buffer. Thereafter, cells were stained in 5 *μ*L Annexin V-FITC and shaked well. Finally, 5 *μ*L PI was added to these cells and incubated for 20 min in a dark place, analyzed by FACS Calibur, Becton Dickinson \[[@B31],[@B32]\]. Caspase 3 enzyme assay ---------------------- Cells were collected after treatment with BTA and OEA at 2.5, 5, and 10 *μ*M for 12 h, respectively. Prepared MGC-803 cells (1×10^6^/mL, 5 ml) were washed twice with cold PBS. Then, 100 *μ*L of lysis buffer was added to the cells for 25 min on ice and centrifuged at 16000 g for 15 min. 80 *μ*L of reaction buffer and 10 *μ*L of Ac-DEVED-*p*NA were added to 10 *μ*L of supernatant liquid. After incubating at 37°C for 2--3 h in darkness, the absorbance was measured at 405 nm, with the lysis buffer and reaction buffer as control Caspase 9 enzyme assay ---------------------- Cells were collected after treatment with BTA and OEA at 2.5, 5, and 10 *μ*M for 12 h, respectively. Prepared MGC-803 cells (1×10^6^/mL, 5 ml) were washed twice with cold PBS. Then, 100 *μ*L of lysis buffer was added to the cells for 25 min on ice and centrifuged at 16000 g for 15 min. 80 *μ*L of reaction buffer and 10 *μ*L of Ac-LEHD-pNA were added to 10 *μ*L of supernatant liquid. After incubating at 37°C for 2--3 h in darkness, the absorbance was measured at 405 nm, with the lysis buffer and reaction buffer as control. Western botting analysis ------------------------ Cells were collected after treatment with BTA and OEA at 2.5, 5, and 10 *μ*M for 12 h, respectively. Western blotting analysis was performed as previously described \[[@B33]\], using the following antibodies at dilutions of 1:500 to 1:1000: anti-p53, anti-Bax, and anti-*β* actin (Cell signaling technology, Beverly, MA). Statistical analysis -------------------- All statistical analyses were performed using SPSS 10.0, and the data were analyzed using one-way ANOVA. The mean separations were performed using the least significant difference method. Each experiment was performed in triplicate, and all experiments were run thrice and yielded similar results. Measurements from all the replicates were combined, and the treatment effects were analyzed. Results and discussion ====================== The roots of *Toona sinensis* collected from Guizhou province were studied, and fifteen compounds were isolated from the plants. The extraction and purification process of the compounds from the plant and their NMR data are presented in Additional file [1](#S1){ref-type="supplementary-material"}. The potential effect of the compounds from *Toona sinensis* was investigated on the viability of MGC-803, PC3, A549, MCF-7, and NIH3T3 cells by MTT assay, with ADM (Adriamycin) being used as the positive control and culture medium containing 0.1% DMSO used as the negative control. The inhibitory percentage of cancer cells was treated with 20 *μ*mol/L of each compound for 72 h. The results are summarized in Table [1](#T1){ref-type="table"}. It could be seen from Table [1](#T1){ref-type="table"} that both of BTA and OEA showed potent antitumor activities against MGC-803 and PC3 cell lines. The inhibitory ratios of BTA and OEA at 72 h after treatment were 56.1% and 45.2% against MGC-803 cells, 63.4% and 42.5% against PC3 cells, 22.1% and 23.6% against NIH3T3 normal cell line, respectively. In addition, BTA also had good activities against MCF-7 cells, with inhibitory ratio of 51.2%. Thus, the two compounds were less toxic on normal cells than on the investigated cancer cell lines. ###### Antitumor activities of the isolated compounds on the proliferation of different cell lines **Compound** **Inhibitory Rate for Different Cell Lines (%, mean ± SD)**^**a**^ ------------------------------------ -------------------------------------------------------------------- ------------ ------------ ------------ ------------ *β*-sitosterol (**1**) 23.5 ± 2.1 16.5 ± 2.3 12.6 ± 3.1 18.9 ± 1.7 5.6 ± 2.4 *α*-Amyrin (**2**) 23.5 ± 5.4 17.8 ± 4.9 7.8 ± 1.5 10.4 ± 1.8 7.6 ± 4.5 Daucosterol (**3**) 12.3 ± 4.1 9.8 ± 3.6 4.5 ± 1.8 7.2 ± 5.2 4.3 ± 2.3 Quercetin (**4**) 17.2 ± 1.7 22.7 ± 1.4 16.9 ± 2.4 42.2 ± 1.6 4.2 ± 2.5 (+)-Catechin (**5**) 52.1 ± 5.7 49.6 ± 2.3 45.3 ± 3.2 37.6 ± 3.9 28.9 ± 4.3 (−)-Epicatchin (**6**) 45.5 ± 4.1 50.6 ± 1.6 47.1 ± 1.1 43.2 ± 3.6 22.5± 3.8 Kampferol (**7**) 58.2 ± 3.0 46.1 ± 5.9 42.0 ± 2.2 39.2 ± 6.8 11.1 ± 6.7 3-Oxours-12-en-28-oic acid (**8**) 45.2 ± 2.0 42.5 ± 1.4 35.9 ± 0.8 37.2 ± 1.5 23.6 ± 1.3 Ursolic acid (**9**) 52.1 ± 2.2 55.6 ± 2.4 37.6 ± 1.7 47.8 ± 1.2 21.7 ± 4.9 Betulonic acid (**10**) 56.1 ± 2.6 63.4 ± 4.2 35.2 ± 2.4 51.2 ± 4.4 22.1 ± 6.2 Gallic acid (**11**) 55.7± 1. 9 40.2 ± 4.2 46.3 ± 3.6 33.1 ± 1.4 13.6 ± 2.2 Betulinic acid (1**3**) 36.9 ± 1.6 23.6 ± 3.4 33.5 ± 2.3 41.6 ± 3.7 23.4 ± 2.9 ADM 92.1 ± 1.3 93.4 ± 2.6 96.2 ± 0.8 91.1 ± 2.2 99.4 ± 0.4 Note: ^a^ Inhibitory percentage of cells treated with each compound 20 *μ*mol/L for 72 h and SD = standard deviation. To best of our knowledge, the two compounds, BTA and OEA, were obtained from *Toona sinensis* for the first time*.* It was also found to have the greatest potency against the growth of human cancer cell lines and little toxic effect on NIH3T3 cells among the isolated constituents. Further experiments found that proliferation of these four cancer cells were significantly inhibited by BTA and OEA in a concentration-dependent manner, as shown in Figure [1](#F1){ref-type="fig"}A and [1](#F1){

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mistrial. I will deny the motion." Defense counsel said nothing further on the issue. The next day the trial court expressed concern that it should have given a limiting instruction regarding Gutierrez's references to Susanville and stated that it would, if requested, strike that portion of the witness's testimony. The court invited defense counsel to propose a limiting instruction. Although defense counsel initially advised he would do so, defense counsel later declined for fear of highlighting the challenged testimony. He explained that, for the same reason, he had not requested a limiting instruction the previous day when he made his motion. (1) Defendant claims the mistrial should have been granted because the prosecutor committed misconduct by improperly eliciting Gutierrez's testimony. Defendant has forfeited this claim. "`[A] defendant may not complain on appeal of prosecutorial misconduct unless in a timely fashionand on the same groundthe defendant made an assignment of misconduct and requested that the jury be admonished to disregard the impropriety. [Citation.]'" (People v. Stanley (2006) 39 Cal.4th 913, 952 [47 Cal.Rptr.3d 420, 140 P.3d 736].) When defendant eventually moved for a mistrial at the conclusion of Gutierrez's testimony, he did so only on the basis of "the response of the witness." He did not argue that the prosecutor had improperly elicited the challenged responses. Additionally, defendant rejected the trial court's offer to admonish the jury. In any event, there was no misconduct. The defense chose to pursue the subject of the collect telephone calls and their cost. The prosecutor's redirect was permissible. Gutierrez nonresponsively volunteered that defendant's calls were made "before he got out in December." (2) The court did not abuse its discretion in denying the motion for a mistrial. "A mistrial should be granted if the court is apprised of prejudice that it judges incurable by admonition or instruction. [Citation.] Whether a particular incident is incurably prejudicial is by its nature a speculative matter, and the trial court is vested with considerable discretion in ruling on mistrial motions. [Citation.]" (People v. Haskett (1982) 30 Cal.3d 841, 854 [180 Cal.Rptr. 640, 640 P.2d 776].) A motion for a mistrial should be granted when "`"a [defendant's] chances of receiving a fair trial have been irreparably damaged."'" (People v. Ayala (2000) 23 Cal.4th 225, 282 [96 Cal.Rptr.2d *199 682, 1 P.3d 3].) Here, Gutierrez's volunteered remarks regarding defendant's phone calls were brief and ambiguous. The court did not abuse its discretion in concluding that any prejudicial effect could by cured by an admonition. Further, we note that as part of defendant's trial strategy, he later established his criminal history and recent incarceration through his own testimony. He claimed he took the victim's car because he had recently been released from prison and his values were poor. Defendant admitted that he threw the gun and ammunition from the car during the police chase and chose to explain that conduct by acknowledging that he was on parole and did not want to get caught with a gun. Defendant asserts that this evidence came in after Gutierrez's testimony and the trial might have proceeded differently but for her remarks. Given the limited nature of those remarks, however, his argument is not persuasive. 2. Asserted Doyle Error Defendant contends the prosecutor committed error under Doyle v. Ohio (1976) 426 U.S. 610 [49 L.Ed.2d 91, 96 S.Ct. 2240] (Doyle), during her cross-examination of defendant and in her guilt phase argument. Specifically, defendant complains the prosecutor improperly questioned his failure to inform the police or prosecutor of his alibi before trial. a. Background At trial, defendant presented an alibi defense that he had never mentioned during his several statements to Detective Castillo. According to testimony, Fred Rose was shot between 6:00 and 6:30 p.m. on January 23, 1992. Defendant testified that after using Rose's ATM card on that date, he tried unsuccessfully to locate a friend in Reseda, and then drove to East Los Angeles to visit Silvia Gomez. He arrived at the home of Gomez's mother about 6:00 p.m. and stayed until 8:00 p.m. He then drove through Los Angeles and Hollywood before continuing to Bakersfield. In his interviews with Detective Castillo, defendant never mentioned his visit with Silvia Gomez. After waiving his Miranda rights, defendant was interviewed twice. Defendant testified that "everything" in his first interview was false and stated, "I would have told them the moon was blue to throw them on a wild goose chase." He told Castillo he got in Rose's car for the first time in Bakersfield and spent no more than 10 minutes in it. Defendant claimed he had not been to North Hollywood for three and a half years. Defendant admitted that he lied in the second interview as well. He testified he was going to tell the officers the truth, but changed his mind. He *200 stated: "I said the hell with them. Let these bastards do their own homework." He initially told Detective Castillo that his mother dropped him off in Lancaster where he worked at construction sites until about 4:00 p.m. After eating at McDonald's, he got a ride from a construction worker to Mojave and hitchhiked from there to Bakersfield, arriving that night. After Detective Castillo confronted defendant with the Chevron credit card receipt and said he had been identified in a photographic lineup, defendant gave yet another explanation of events. In this version, defendant, while walking out of Lancaster on the Sierra Highway, saw the Oldsmobile with the keys inside and took it. He found the gun, wallet and credit cards in the car. He stopped at the ATM for money and "wanted to go to East L.A." to "visit some of my homeboys." Defendant testified that he did not know he had an alibi until he later learned when Rose was shot. Defendant claims that in certain exchanges during cross-examination, the prosecutor improperly used his post-Miranda silence to impeach his alibi. He points to several exchanges with the prosecutor, including the following colloquy: "Q. Do you enjoy being in jail? "A. No, I do not. "Q. Can you give us an explanation why you did not tell Detective Castillo that you were somewhere else [at the time Rose was killed]? "A. Because he probably would not have believed me at that point in time. "Q. Did you even try? "A. I figured there was no use even trying with him. "Q. Why would you figure there is no use even trying? You gave him all kinds of other stories you wanted him to believe. "A. Because... I did not know exactly what time that murder happened. I did not know exactly where I was at that point in time. "Q. Well you could have done the exact same thing. Just told him everything you did the whole day. *201 "A. I imagine I could have done that, but I didn't. "Q. Why not? "A. I wasn't into helping him along with his investigation. He was trying to get me. "Q.... [T]his investigator is trying to find out who committed a murder. You're his only suspect. If you knew you didn't commit the murder, why would you care if you're helping him? It is helping yourself, isn't it? It's not helping him. It's helping you. "A. Past experience, every time I reach my hand out to help I get it slapped." A short time later, the prosecutor and defendant had the following exchange: "Q. Isn't it true, sir, you had many opportunitiesDetective Castillo gave you opportunity after opportunity after opportunity to tell him where you were that entire day? "A. Yes. "Q. You never did, did you? "A. No, I did not. "Q. And in the year and eight months since this murder you have been in jail, correct? "A. Yes, I have. "Q. How many times have you seen him in the courtroom? "A. Numerous. "Q. Have you ever once tried to say, `Detective Castillo, it wasn't me?' I mean, by now you have got the time of the murder, right? "A. Yes." When the prosecutor asked why defendant did not tell Detective Castillo that Silvia Gomez could explain his whereabouts at the time of the murder, *202 defendant replied, "I didn't figure it would do any good at that point. Especially after the prelim." Defendant also stated that he was serving a one-year sentence for a parole violation at that time. The prosecutor asked, "So you figured, `I might as well stay in jail because I'm going to be doing this on a violation anyway.' Is that what you're telling us?" Defendant answered yes. The prosecutor then asked defendant why he did not contact Castillo about his alibi when the one-year sentence was completed. Defendant replied that he had told his attorney about his alibi. The prosecutor stated, "I'm not talking about your attorney. Talking about you." The prosecutor asked why defendant had not telephoned Castillo. Defendant replied that he "didn't figure at that point it would do any good." The prosecutor asked defendant why he had not spoken to her about his alibi during the numerous court appearances in the case. Defendant replied that the

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pressure. Why? Because they really, really want those tax cuts for the rich, and they are apparently willing to see any norm or institution fall in order to get them. And the planet too, if need be. And the Democrats? Oh-oh! They have been voted completely out of power. So can it get any darker? Well, yes, a lot. We may live to see this worst of all worst-case scenarios play out over the next few years, and we can throw in a blundered-into war while we’re awful-izing here. AD However. I am going to return to Plan B, which is not so unrealistic as it might seem. Because if history has taught us anything, it’s that it loves to deliver the unexpected. Best-laid plans of mice and monsters, you know. AD The remnant pieces of American democracy are not inconsiderable. The nation has a long history of slow, agonizing progress toward inclusion, reason and overcoming our worst impulses. The vast numbers of Americans with better value systems than our president-elect are still here. It is not only those with grudges against minorities who are capable of making their voices heard. The facts of the world do not disappear, and neither does the arc of history, even though it currently looks more like a tangle of knotted string than a bow. I expect Trump to do his damnedest, and I chose that word deliberately, to twist this nation to satisfy his own insatiable ego needs. And he now has staggering power at his little fingertips.New-Look Lines Rolled Out BOSTON, MA – After the Boston Bruins scored just one goal against the Washington Capitals last night for the third time in four games, Head Coach Claude Julien unveiled a brand new look at practice Friday at TD Garden. At first sight the changes look drastic, but it’s not unfamiliar territory for anybody according to Campbell. “Something we as players are used to throughout our career is having to adapt and play with different players,” Campbell said. “If you look at the changes, they look drastic but they’re really not. “Marshy and Thorty and I played together almost half a season last year and at one point or another everyone’s played with everybody in this room. We look at it as a change, and hopefully it jumpstarts some offense.” While Brad Marchand has struggled to register a point in the series, Campbell felt that No. 63 could benefit from playing on his line. “Just playing with two great players builds your confidence,” Campbell said jokingly. On a more staid note, Campbell said that his line’s simple play may help generate more on the score sheet. “A lot of time if you’re struggling to score or struggling in any area of your game anyone will tell you go back to basics and keep it simple,” Campbell said. “And that’s what Thorty and I always do. We try to play high energy and be physical and in playoff hockey, physicality is key and sometimes the best recipe for a change for some offense is to keep it simple.” Like Marchand, Seguin is without a point thus far in the series and was asked if he thought a message was being sent with the line change. “I don’t know,” Seguin said. “I think when you’re not scoring goals as a team, what’s the thing you do? You switch things up, you get guys playing with different guys and playing with Kells [Kelly] and Pou [Pouliot], obviously they’re two great players so hopefully we can pop a couple.” After last night’s loss, David Krejci freely used the word frustration to describe his attitude after the game. But Seguin said he felt it’s more of a determination to score, rather than a frustration. “When you get 45 shots on net, and when you look at the actual scoring chances they’re pretty equal, that’s not very acceptable,” Seguin said. “We have to generate more scoring opportunities, kind of like Timmy [Thomas] said getting more guys to the net and banging bodies around the crease.”Sibship characteristics and risk of allergic rhinitis and asthma. Studying associations between sibship characteristics and allergic diseases in detail may contribute clues to their etiology. The authors studied associations between sibship characteristics and risk of self-reported allergic rhinitis and asthma among 31,145 pregnant women participating in a nationwide study in Denmark during 1997-2000. Increasing sibship size was associated with a decreased risk of allergic rhinitis and asthma with allergic rhinitis but not with asthma without allergic rhinitis. The protective effect of having older siblings was stronger than the protective effect of having younger siblings for both allergic rhinitis and asthma with allergic rhinitis. There was no association between interval to closest older or younger sibling and risk of allergic rhinitis or asthma with allergic rhinitis, while the risk of asthma without allergic rhinitis increased with intervals of 2 or more years compared with less than 2 years to the nearest older sibling. The protective effect of having siblings on the risk of asthma with allergic rhinitis could be explained by a protective effect of siblings on the risk of allergic rhinitis alone. In conclusion, our findings suggest that different etiologic mechanisms are involved for allergic rhinitis and asthma with respect to the effect of sibship characteristics. Furthermore, the findings that allergic rhinitis was associated with the number of younger siblings but not with the age interval to younger siblings support the hypothesis of an influence of postnatal mechanisms and suggest that these mechanisms may not necessarily be operating only in early life.A personal computer (PC) display typically shows a stack of application windows corresponding to different types of work a user may be doing (for example, word processing, e-mail, spreadsheet, video, etc.), with the currently active application window at the top of the stack, thus appearing closest to the user. When a user changes from one activity to another, these windows are re-composed into a new desktop image, bringing a new application window to the fore. Future PC product plans call for composing the application windows using three-dimensional (3D) animation techniques to provide the user with a richer visual experience where the animations move smoothly. To make the animations move smoothly, they must be free from jerkiness that can be caused if the desktop image is not composed rapidly enough. Unfortunately, composing a PC desktop image at sufficiently high rates requires excessive amounts of graphics memory bandwidth, which increases costs to levels that may be unsustainable in products targeting the mobile and low cost PC markets. Conventionally, to deal with inadequate computational or memory resources, frames are simply dropped. Since image information representing original content is discarded, the result often is animation that is jerky in appearance, similar to animated video often seen on personal computers today. This frame skipping may cause the video frame-rate to drop below the frame rate desired to perceive smooth motion. As a result, low bit rate video may at times look jerky to the user.Hrithik Roshan asks Karan Johar to shoot 'K3G' sequel in space! Actor Hrithik Roshan, who played the role of Bollywood superstar Shah Rukh Khan's younger brother in Karan Johar's 'Kabhi Khushi Kabhie Gham...', has asked the filmmaker to shoot the sequel to the 2001 drama film in space. Karan posted on Twitter a video of 1962 science fiction animated children's television show “Fireball XL5”, which followed the missions of spaceship Fireball XL5, commanded by Colonel Steve Zodiac of the World Space Patrol. “'Fireball XL5' - Start and Theme Song - YouTube who remembers this? #childhoodtelevision,” the “My Name is Khan” director captioned the video.The applicants proposed to design, construct, and test a prototype scanning device capable of reconstructing regional, optical absorption in three dimensions within the human breast. The device will consist of an array of sixteen,.25" diameter transducers aligned along a 60 degree, 15 cm radius arc. This arc of transducers will be scanned axially to acquire a set of photoacoustic "projections" over a little less than 2p steradians. Photoacoustic image reconstruction will be performed using a modified, inverse Radon transform. Imaging performance will be evaluated in terms of contrast/noise and spatial resolution as a function of irradiating energy (infrared and microwave) and depth within a tissue-mimicking phantom. Based on the Phase I results, specifications will be determined for a clinical prototype photoacoustic scanner, to be designed, constructed and tested in Phase II.29-30 October 2016 - Analog Forum - Krefeld - Germany We participated to the Analog Audio Association Forum in Krefeld (Germany) with our Tempesta 20, presented by Thomas H. Diehl producer of the Holz-Akustik racks.Here You can find more information about the show, and here You can download the official flyer. Thomas H. Diehl was really surprised about the quality of the presentation. And this is his comment about the show (in German):Terms and Conditions please read carefully and feel free to contact us with any questions you may have This web site is owned and operated by Myon Life Ltd who are completely dedicated to your total satisfaction. By accessing this site, you are acknowledging that you have read, understand and agree, without limitation or qualification, to be bound by these terms and conditions. This site is designed to make your shopping experience as safe and enjoyable as possible. If you have any questions in regards to our products or the website, you can contact us at

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everyone. A productivity system that doesn't make you feel good about your daily life is not be sustainable in the long run. It doesn't matter how effective it is, that's not a life you want to be living. What makes you feel better about your daily life will depend on your temperament. The author of this blog post found that GTD resulted in his feeling like he had a never-ending river of stress ahead of him. GTD failed for him. Another example where GTD fails is for anyone who is doing sustained creative work. As Paul Graham describes in [http://www.paulgraham.com/makersschedule.html](http://www.paulgraham.com/makersschedule.html), it is very important for those people to have large blocks of time set aside for focused work. GTD's focus on breaking things into simple tasks whose execution is routine is the antithesis of how work needs to be organized for a maker. That said, GTD is life-changing for many people. If it works for you, by all means do it. But don't make the mistake of trying to convert everyone else to it. It isn't always right. ~~~ luketych GTD IS for everyone. All GTD is, is acknowledging how our brains function at a very fundamental level, and then building a trustable system around that. Why can't create tasks work in GTD? GTD methodology doesn't say that you HAVE TO break everything up into 2-minute chunks. It can be 2 hours set aside for creativity. Saying "X doesn't work for everyone" sounds nice, as does "everything in moderation." But I get skeptical when someone uses "everything in moderation" to excuse their smoking habit, or "___ is NOT for everyone". Hundreds of years ago I'm sure there were people arguing that "reading and writing is not for everyone." Eating vegetables is not for everyone, etc. ~~~ orblivion I get skeptical when people are so enthusiastic about some newfangled anything that they compare it to reading and eating vegetables. GTD _could_ be that good but it's an extraordinary claim and it deserves to be scrutinized accordingly. ~~~ luketych As you should. It's not my job to sell Gtd to you. But I have to challenge your emotional intelligence if you let other peoples' enthusiasm cloud your own view. ~~~ orblivion I base it off my my own experience getting enthusiastic about things. ~~~ luketych lol, but isn't your own enthusiasm at least somewhat affected by other peoples' enthusiasm or lack there of? ~~~ orblivion Sure. I'm not sure what your point is, maybe my point wasn't clear. I'm just saying that I've been in the position at least once where I was excited about something and I overblew its potential in solving problems. So when I see others doing it, I can relate, but know that they're likely clouded in their judgement. ------ moron4hire I don't think that was a failure of GTD. I think that was a failure to understand your own limitations and what you're realistically going to be able to accomplish in any given timeframe. It really sounds like a fundamental failure to _properly_ understand GTD. If you actually read _the book_ \--rather than the BusinessInsider, et. al. listicles summarizing it--Allen makes the point that the most important feature of any task tracking system be that it is not cumbersome. All else be damned. If whatever system you're using to keep track of what you need to do is getting in the way of keeping track of what you need to do, then it is no good. He also makes the point that nobody is meant to do everything in the book. The book is meant to be a cookbook, you are meant to try different things in the book up to the point of gaining control of your work _and then put the book down_. You're supposed to stop reading GTD when you start to get things done. Don't mess with a good recipe. I keep a single sheet of paper as my TODO list. If it doesn't fit on the paper, it doesn't go on the list. It's one list for both work and personal issues, because I only have one life, I can't clone myself and work on two lists in parallel. I scratch things off and reuse the paper until it's full. I then rewrite the list on a new sheet of paper, with items that have gone undone for a long time naturally bubbling up to the top of the list. And if something has been ignored at the top of the list for a long time, I just throw it away. If it didn't get done in the last month, clearly it's not that important. If it were more important, I would have made the time to do it. Get better about throwing away your emotional baggage. ------ VladimirGolovin I too find GTD unsuitable for creative work, mostly because it doesn't handle open-ended, non-tickboxy tasks well, though I can't say that I was using GTD properly -- for example, I couldn't bring myself to do weekly reviews. Overall, GTD felt like it requires too much willpower to run. Have you tried Mark Forster's Autofocus or Final Version Perfected systems? If not, you owe yourself a try. The systems, at their core, are very simple: 1\. You have a long list of tasks (the same 'ubiquitous capture' principle as in GTD and other systems) 2. You scan the list for tasks that'stand out' for you as 'ripe' to be done / worked on. This means that you're mentally ready to do these tasks. 3. Work these tasks for as long as you feel like. It's not necessary to finish these tasks. 4. After you've dont with a task, you either cross it off the list, or re-append it to the end of the list. I found his systems much more tolerant of creative work, and much less willpower hungry. A downside of these systems is that they're not capable of handling tasks with start / due dates. Also, regarding de-cluttering todo lists, I firmly believe that: 1\. ALL your tasks and actionable thoughts must be captured in your system. 2. Your _current_ todo list must only show items that you are ready to do _right now_, at the moment. For example, your todo list shouldn't show the task 'Vacuum the floor' if you're not at home. Therefore, there must be ways of de- cluttering your todo list that allow you to defer the tasks until your external (or internal!) conditions are more conducive to working on these tasks. (I got fed up with the inability of most todo apps to do the above, so I'm working on my own todo app). ~~~ sametmax This is actually a perfect application of GTD. Most people don't realize how flexible GTD is, and feel like everythin must be well define, and have a time frame. It doesn't. You have the reviews for that. You have the "projects" list for that. You have "waiting for" for that. "Spending time on 'creative job x'" is actually a perfectly good task name to add to your "project" list. In your daily review, you scan the one you want to work and and you add the ones you feel like to your "next" list. GTS itself must NEVER be applied as-is, and should be adapted to your line of work, rythm, life style and personnalité. And it's very good at it. ~~~ VladimirGolovin I guess I couldn't stomach the idea that GTD mandates dedicated review stages, while in Autofocus / FVP and in my own system review is a continuous process. Ideally, I'd like to have the ability to do'makeshift reviews' per-task, and on different timescales. For example, if I don't feel like doing Task X today, I'd defer it for 5 days, so its next review will happen in 5 days. But if there's another task I'll probably want to do tomorrow, I'd defer it to tomorrow, so I'll review it tomorrow. On the other hand, I do seem to have a de-facto review stage. In the morning I usually go through my task list in Wunderlist (which I hate but use daily) and mark items I'd like to do today. But this is probably because Wunderlist doesn't offer a proper Defer / Hide Until ability that doesn't screw with tasks' due date. (And I have a recurring task 'Review all items', a relic from a bygone era when I attempted to do GTD properly.) ------ rbrogan From what I am reading, the author is saying they are effectively time slicing their

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, the GAF domain of Hik2, which is found in class I Hik2s, might be involved in perceiving additional signal(s) such as redox or it might bind small ligand(s) required to regulate its autophosphorylation (Allen [@CR2]). Indeed, the Hik2 homologue in higher plants has been shown to bind the PQ analogue DBMIB with a *K*~d~ value similar to that of other quinine-binding proteins (Puthiyaveetil et al. [@CR33]); it also forms a quinone adduct (Ibrahim et al. [@CR18]). Figure [11](#Fig11){ref-type="fig"} proposes a working model of signal perception mechanism of Hik2. In the absence of increased salt concentration or redox stresses, the Hik2 is autokinase-active and transfers phosphoryl groups to the response regulators Rre1 and RppA, while Phospho-Rre1 activates genes coding for light-harvesting phycobiliproteins. However, in the presence of salt/osmotic stress, the active hexameric form of Hik2 is rearranged into the inactive tetrameric form. Rre1 and RppA, therefore, remain in their unphosphorylated states. As a result, Rre1 can no longer act as a repressor of salt/osmotic tolerance genes, in turn releasing the repression of their transcription. We are unable to determine the precise symmetry of the oligomeric forms described here. For example, the hexamers could be either trimers of dimers of 32-point group symmetry or hexamers of hexagonal symmetry (point group 6). Similarly, the tetramers could be dimers of dimers (point group 22), or tetramers of tetragonal symmetry (point group 4), and tetragonal tetramers may assemble into octamers as dimers of tetramers (point group 42). Conversion between hexamers and tetramers is likely to involve only oligomers of the aforementioned symmetries. This conversion between oligomers would be possible if conformations of the subunits change during the transition. The molecular basis of a mechanism by which elevated Na^+^ concentrations trigger recombination of hexamers into tetramers could therefore be twofold. Na^+^ may interfere with salt bridges that stabilise intersubunit interfaces at low salt concentrations. In addition, Na^+^ may induce conformational changes in the protein subunits thus leading to the disruption of intersubunit interactions in the hexamers and favouring the formation of new protein-protein interfaces that result in inactive tetramers.Fig. 11Proposal for a Hik2-based signal transduction pathway in cyanobacteria. The hexameric form of Hik2 is autokinase-active, and the oligomeric state of Hik2 is regulated by signals from Na^+^ and the photosynthetic electron transport chain. The active hexameric form of Hik2 is converted to an inactive tetramer upon salt stress Hik2 is of special interest because of the presence of its homologue in all known cyanobacteria as well as in chloroplasts (Table [2](#Tab2){ref-type="table"}). In eukaryotes, the homologue of Hik2 is termed CSK, a protein that is encoded in the nucleus and synthesised in the cytosol for post-translational import and processing in chloroplasts (Puthiyaveetil et al. [@CR32]; Puthiyaveetil et al. [@CR35]). CSK couples the redox state of the photosynthetic electron transport chain to chloroplast gene transcription (Puthiyaveetil and Allen [@CR30]) by acting on plastid transcriptional regulators (Puthiyaveetil et al. [@CR33]; Puthiyaveetil et al. [@CR34]). It will be important to determine whether the oligomerisation that we propose as the basis of regulation by sodium ions is also a mechanism that extends to redox regulatory control of the activity of all Hik2 proteins, including CSK. The oligomeric states of Hik2 and CSK may determine their sensitivity and the amplification gain (Koshland et al. [@CR21]) of the cell's response to changes in both sodium ion concentration and redox state of photosynthetic electron carriers. IMI thanks Queen Mary University of London for a graduate teaching studentship. LW thanks the China Scholarship Council (CSC) and Queen Mary University of London for financial support. SP held a Leverhulme Trust early-career post-doctoral research fellowship. JN is grateful for the continued support of the JST CREST Grant Number JPMJCR13M4, Japan. JFA acknowledges the support of research grant F/07 476/AQ and fellowship EM-2015-068 of the Leverhulme Trust. Conflict of interest {#FPar14} ==================== The authors declare that they have no conflict of interest. [^1]: Handling Editor: Peter Nick Q: Python pass argument to constructor by reference import pandas as pd class MyClass(): def __init__(self, df): self.df = df def edit(self): self.df = self.df[~self.df['numbers'].isin([2,4,6,8,10])] df = pd.DataFrame([1,2,3,4,5,6,7,8,9,10], columns=['numbers']) obj = MyClass(df).edit() print df I am expecting print df to print the dataframe which has been reassigned after the filteration function. But this stil prints the dataframe which is before the edit function modify it. How can my outer variable still track the changes happend to the df inside class A: How can my outer variable still track the changes happend to the df inside class The way you are trying to do this, namely by reassignment, it's impossible. Names do not "see" the reassignment of other names (imagine the catastrophe if they did). Your only chance without reassigning df here is to mutate the dataframe. All you currently do is to create a new object and reassign self.var. The var outside of your class does not care about that and still points to the old object. Of course the sensible thing to do would be to just reassign df to the return value of some function or method, i.e.: def compute_new_df_from_old_df(df): return df.foo()[bar] df = <some dataframe> df = compute_new_df_from_old_df(df) Recipe, Information, how-tos and much more.. Chocolate Chip Muffins Discuss a chocolate sweetheart’s fantasy, these Chocolate Chip Muffins are certain to satisfy the chocolate significant other in your life. Chocolate Chip Muffins are brought up a score with the expansion of chocolatechips blended into the hitter. At that point, more chocolatechips are sprinkled on upper just before they go into the stove. The result is the perfect mixture of chocolate, and well more chocolate. For Chocolate Chip Muffins Lovers What I cherish about these little Chocolate Chip Muffins is that they aren’t excessively sweet. Don’t get me wrong, in any case they have little sweetness to them then again; they are not cake or cupcake like sweet. Furthermore when they leave the stove, they are super damp and simply ideal for a unique breakfast. These Chocolate Chip Muffins are best served new out of the stove, as we did get to be mindful of they tend to lose a portion of the wetness when they are consumed as remains a day or two later. What you need to cook Chocolate Chip Muffins? On the off chance that you are searching for a simple formula for Chocolate Chip Muffins, this totally possesses all the necessary qualities. You don’t even need to get out your blender. All you will need to make these without any preparation is several enormous dishes, and huge wood spoon. OK, it doesn’t need to be a wood spoon; however that is the thing that I use for the reason that it’s my top pick. Doesn’t everyone have a most loved kitchen utensil? Simply take a gander at the chocolate overflowing from these biscuits. Yum! Wouldn’t precisely call these sound however serve some new foods grown from the ground close by them and it may help ease any blame you have over serving chocolate for breakfast (which I am never contradicted to!). How to make Chocolate Chip Muffins? Prep Time: 7mn Cook Time: 20mn Total Time: 27mn Ingredients 1 3/4 measures broadly functional flour 1/2 mug sugar 1/4 mug tan sugar 1/4 mug unsweetened cocoa powder (Dutch process in the event that you have it)Womblife Womblife is an album by American fingerstyle guitarist and composer John Fahey, released in 1997. It was one of three releases by Fahey that year. History Womblife continues John Fahey's career resurgence, again bearing minimal resemblance to his earliest work. It incorporates sound collages and experimental music. Working with Jim O’Rourke, Fahey taped Womblife in the younger musician’s bedroom. O'Rourke has been long associated with the experimental and improv

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comum. Na rua, Marta via como os olhos de Dominika saltavam entre os rostos das pessoas e as entradas dos prédios, ao longo do passeio, do outro lado da estrada, usando movimentos normais para disfarçar os olhares constantes. Quando estavam sentadas juntas num café, havia o vislumbre de intuição gratificante, a sugestão de jovialidade, o sorriso brilhante. Marta identificou facilmente o uso quase inconsciente que Dominika fazia da beleza – olhos, sorriso, corpo – nas suas relações com as pessoas. E, quando falavam, Marta reconheceu as técnicas de conversação e extração de informações que Dominika usava. Uma criatura extraordinária, pensou Marta, e operacional! Beleza, cérebro, habilidade e olhos azuis incandescentes. Era evidente que ela sabia o seu dever, amava o seu país, mas também havia algo abaixo da superfície, uma corrente subterrânea que borbulhava, invisível. Orgulho, raiva, desobediência. E algo mais, difícil de definir, um lado secreto, uma paixão pela rebeldia, como se namorasse com o perigo. Marta perguntou-se quanto tempo demoraria esta jovem, com o seu olhar perspicaz e instintos naturais, a perceber que o trabalho do Centro era pokazuhka, algo feito apenas pelas aparências, para inglês ver. O rezident Volontov era um exemplo extremo da ética laboral, o tipo de funcionário que geria o KGB e o Kremlin há setenta anos. Começaram a sair juntas da embaixada ao final do dia, parando num bar da zona para um copo de vinho e uma fatia pecaminosa de tarte de caviar carregada de crème fraîche e queijo. Falavam da família, de Moscovo, das suas experiências. Dominika não mencionou a Escola de Pardais. Marta ria-se e fazia rir Dominika, e caminhavam de braço dado pelo passeio ao anoitecer. Uma noite, num bar, depois de despachar rapidamente um alemão nojento que não as deixava em paz, Marta contou a Dominika a história da sua vida, a sua carreira como Pardal. Estava orgulhosa de ter servido o seu país; não pensava nos anos infernais do KGB. Não se mostrava minimamente envergonhada de quem era nem daquilo que fizera. O lábio inferior de Dominika tremeu, olhou para a amiga e começou a chorar silenciosamente. Foi uma longa noite, depois disso, mas Marta ficou a saber tudo sobre ela. A missão contra Nate, o tio Vanya, a Escola de Pardais, o francês Delon, até Ustinov. As palavras brotaram de Dominika numa torrente. Não pensaram em manipulações nem em extração de informações. Daí em diante as duas mulheres ficaram, simplesmente, amigas. Noite após noite, calma e reservada, Marta escutava e pensava: Céus, como os vlastiteli, os patrões, espremeram tanto desta rapariga em tão pouco tempo. Contudo, Marta via força em Dominika, e via algo mais. Marta desconfiava de que a exposição de Dominika ao jovem e descontraído agente americano da CIA estivesse também a criar reações mais profundas. Dizê-lo seria insinuar que Dominika não conseguia cumprir corretamente a sua missão, portanto Marta não disse nada. – Não sei – disse Dominika. – Ele é arrogante, é brincalhão, não gosta da Rússia, ou pelo menos não nos dá grande crédito. O tio Vanya acredita que ele é um operacional desesperado. – Parece ser desagradável – disse Marta. – Mas isso deve tornar mais fácil para ti trabalhar contra ele... até dormir com ele... para obteres aquilo que pretendes. – Acendeu um cigarro e olhou para Dominika, recostada no banco. Iam no terceiro copo de vinho. – É mais frustrante do que desagradável. Mas simpático. – Suspirou. – Tenho de dizer ao Volontov quando achar que ele está operacional, distraído. Querem apanhá-lo com o seu informador. – Dominika estava a sentir os efeitos do vinho. – E conhece-lo suficientemente bem para isso? – perguntou Marta. – Conseguirás perceber? Dominika afastou uma madeixa de cabelo da testa. – Acho que já percebi... quer dizer, sei que sim – respondeu ela. – E correste a informar o coronel Volontov – disse Marta. Já sabia o que estava a acontecer. – Não propriamente – confessou Dominika. – Disse-lhe que continuaria atenta. – E não o informaste de que desconfiavas que o teu jovem americano estava a entrar em ação. – Ele não é o «meu jovem americano» – disse Dominika, de olhos fechados. – Mas suspeitas que é isso que se passa, e o Volontov perguntou-te diretamente e tu não disseste nada, correto? – perguntou Marta, inclinando-se para Dominika. – Abre os olhos, olha para mim. Ela abriu os olhos. – Correto. Não disse nada. – Fechou os olhos. Marta bebeu um gole de vinho e pensou, com alguma frieza, que Dominika não só cometera traição contra o Estado – dizer traição contra a Duma parecia ridículo – ao não transmitir as informações e ao mentir a respeito delas, como também fizera com que, nessa noite, Marta se tornasse igualmente culpada de traição ao tomar conhecimento do crime. Estendeu o braço e apertou a mão de Dominika. – Tens de ter cuidado – disse. Marta tinha dedicado a sua vida ao Estado, ignorara durante anos os seus excessos e contribuíra pessoalmente para a desgraça de homens cujo único pecado fora sucumbir aos prazeres da carne. No entanto, por dentro, há muito que rompera com esses filhos da mãe. Sabia a situação em que Dominika se encontrava. As bestas, pensou, esvaziarão completamente esta rapariga bela e inteligente e depois livrar-se-ão dela. E, se aquilo que ela estava a fazer afetasse, ainda que remotamente, Vladimir Putin, seria mortalmente perigoso. O conhecimento de Dominika era como um saco de cobras fechado com um nó – seguro, de momento, mas era melhor não bater com ele contra a parede. A curta visita de MÁRMORE a Helsínquia foi um êxito em muitos aspetos. Primeiro, MÁRMORE encontrou-se e fez progressos significativos com Trunk, o ministro do Comércio, estabelecendo assim de forma indubitável a necessidade continuada de manobrar o extravagante canadiano. Em segundo lugar, três noites de reuniões até de madrugada com Nate, no Hotel GLO, já tinham produzido oito relatórios de informações de nível elevado (com material suficiente para, possivelmente, mais trinta e sete) sobre as operações do SVR na Europa e na América do Norte. Terceiro, MÁRMORE fornecera o nome de um comissário assistente na Direção de Política E

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Polarity Regulation 6. See also 7. References 7. DYNAMIC INTEGRATION: DYNAMICS | Theory of Cargo and Membrane Trafficking 1. Abstract 2. Introduction 3. Theory of the Endosomal Network 4. Regulation of the Microscopic Processes 5. Relation to Kinetics of Total Cargo Pool 6. Implications for Cargo Sorting 7. Conclusion 8. See also 9. References 10. Further Reading 8. DYNAMIC INTEGRATION: DYNAMICS | Transcription Factor Networks 1. Abstract 2. Introduction 3. Local Properties of GRNs 4. Motifs 5. Global Properties of GRNs 6. Conclusions 7. See also 8. References 9. Further Reading 3. Vertical Integration 1. Modeling 1. VERTICAL INTEGRATION: MODELING | Vertical Integration 1. Abstract 2. Introduction 3. The Multiple Time and Spatial Scales Associated with Cellular Biology 4. Approaches for Linking Scales in Multiscale Models: 'Top-Down', 'Bottom-Up,' and 'Middle-Out' 5. Mathematical and Computational Representations of the Components of a Multiscale Model 6. Assembling Multiscale Modeling 7. Software for Multiscale Modeling 8. Applications of Multiscale Modeling and Two Case Studies 9. Challenges Associated with Multiscale Modeling 10. Summary 11. Conclusions 12. See also 13. References 14. Further Reading 2. VERTICAL INTEGRATION: MODELING | Computational Approaches for Multiscale Modeling 1. Abstract 2. Glossary 3. Introduction 4. Multiscale Modeling 5. Discussion 6. Acknowledgments 7. See also 8. References 9. Further Reading 10. Relevant Website 3. VERTICAL INTEGRATION: MODELING | Cardiac Modeling 1. Abstract 2. State-of-the-Art in Cardiac Cell Modeling 3. Human Models of Cardiac Cell Electrophysiology 4. Modeling Variability in Cardiac Cell Electrophysiology 5. Whole Organ Cardiac Modeling 6. Conclusions and Outlook 7. References 8. Relevant Website 2. Applications 1. VERTICAL INTEGRATION: APPLICATIONS | Mathematical Approaches to Studying Inflammation 1. Abstract 2. Introduction 3. A Simple Mathematical Model Capturing the Resolution of Inflammation 4. Current Mathematical and Computational Models of Inflammation 5. Early Events, Leukocyte Responses to Bacteria 6. Inflammatory Cytokines, TNF-Therapy 7. Tissue Damage and Wound Healing 8. Inflammation and Progression to the Immune Response 9. Conclusions and Future Challenges 10. See also 11. References 2. VERTICAL INTEGRATION: APPLICATIONS | Angiogenesis 1. Abstract 2. Glossary 3. Vascular Evolution 4. Developmental Vasculogenesis 5. Capillary Structure 6. Primary Factors Controlling Angiogenesis 7. Hypoxic Induction of Angiogenesis 8. Sprouting Angiogenesis 9. Intussusceptive Angiogenesis 10. Arterial and Venous Vessels 11. Summary 12. References 3. VERTICAL INTEGRATION: APPLICATIONS | A Review on Various Mathematical Modeling Approaches for Wound Healing 1. Abstract 2. Wound Healing and the Need for Modeling 3. Evaluation of Several Mathematical Approaches 4. Conclusions 5. See also 6. References 4. VERTICAL INTEGRATION: APPLICATIONS | Multiscale Analysis of Morphogenesis 1. Abstract 2. Introduction 3. Vertical Integration 4. Analyzing Cell Behavior 5. Mathematical Models for Studying Collective Cell Behavior 6. Examples of Vertical Integration Studies 7. Conclusion 8. Acknowledgments 9. References 10. Further Reading 5. VERTICAL INTEGRATION: APPLICATIONS | Neurogenesis in the Adult Brain 1. Abstract 2. Introduction 3. Historical Perspective 4. Identity of Adult NSCs 5. Cell Proliferation in the SVZ 6. Neuronal Migration in the RMS 7. Neuronal Differentiation in the Olfactory Bulb 8. Potential Functions of Adult Neurogenesis 9. Potential Applications 10. Conclusion 11. References 12. Further Reading 4. Horizontal Integration 1. Networks 1. HORIZONTAL INTEGRATION: NETWORKS | Understanding of 'Networks' _In Vitro_ and/or _In Vivo_ 1. Introduction 2. Networks in Cancer 3. Concluding Remarks 4. See also 5. References 6. Relevant Website 2. Omics 1. HORIZONTAL INTEGRATION: OMICS | Connecting Evolutionary Genomics to Cell Biology 1. Abstract 2. Genomics for Old and New Questions 3. Case Studies: New Genes for Old and New Functions 4. Gene Traffic 5. Gene Regulatory Networks 6. Cell Division 7. Protein Traffic 8. Perspectives 9. Acknowledgments 10. References 2. HORIZONTAL INTEGRATION: OMICS | Transcriptomics 1. Abstract 2. Glossary 3. Introduction 4. Evolution of High-Throughput Transcriptomic Technologies 5. Exploring the Interactive Transcriptome 6. New Technologies for mRNA Transcriptomics 7. Integrating Transcriptomics with Other Omics 8. Conclusion 9. See also 10. References 3. HORIZONTAL INTEGRATION: OMICS | The Advent of Mass Spectrometry-Based Proteomics in Systems Biology Research 1. Abstract 2. Systems Biology and Proteomics 3. Liquid Chromatography-Coupled Tandem Mass Spectrometry 4. Systems Biology Application for High-Throughput Proteomics 5. Outlook 6. Acknowledgments 7. See also 8. References 4. HORIZONTAL INTEGRATION: OMICS | Phosphoproteomics: Approaches, Developments, and Challenges 1. Abstract 2. Introduction to Posttranslational Modifications 3. Protein Phosphorylation 4. Phosphopeptide Enrichment 5. Large-Scale Phosphoproteomics Strategies 6. Phosphopeptide Fragmentation 7. Quantitative Phosphoproteomics 8. PTM Cross Talk and PTM Coding 9. Challenges in Phosphoproteomics 10. Conclusions 11. See also 12. References 5. HORIZONTAL INTEGRATION: OMICS | Interactomes - Scaffolds of Cellular Systems 1. Abstract 2. Introduction 3. Methods to Map Interactomes 4. Applications of Interactome Maps 5. Perspectives 6. See also 7. References 6. HORIZONTAL INTEGRATION: OMICS | Metabolomics in Cell Biology 1. Abstract 2. Introduction 3. Conducting a Successful Metabolomics Study 4. See also 5. References 3. Analyses and Tools 1. HORIZONTAL INTEGRATION: ANALYSES AND TOOLS | Network Modeling of Heterogeneous Datasets 1. Abstract 2. Introduction 3. Overview 4. Network Algorithms 5. See also 6. References 2. HORIZONTAL INTEGRATION: ANALYSES AND TOOLS | Stochastic Analysis of Nongenetic Cell-to-Cell Heterogeneity 1. Abstract 2. Glossary 3. Introduction 4. Cell Signaling 5. Variability in Gene Expression 6. Single-Cell Analysis 7. Modeling and Analysis of Stochastic Data 8. Connecting Heterogeneity at Multiple Levels 9. Conclusion 10. See also 11. References 3. HORIZONTAL INTEGRATION: ANALYSES AND TOOLS | Systematic Methods to Interrogate Genetic Perturbations and Map Phosphorylation-Dependent Signaling 1. Abstract 2. Acknowledgments 3. See also 4. References 4. HORIZONTAL INTEGRATION: ANALYSES AND

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for overnight at 4 °C. Finally, cells were washed three times with PBS and DAPI (1 µg/ml) was used for nuclear stain. Coverslips were mounted onto slides using 70% glycerol^[@CR57]^. Images were acquired using a laser scanning confocal microscope (Carl Zeiss LSM 510 META, Jena, Germany) equipped with a plan apochromat 63x oil/1.4 NA DIC objective, and 3x optical zoom over 63x objective (189 X). Immuno-histochemistry of ITGB8 and FAK {#Sec19} -------------------------------------- The immunolocalization study was done according to the earlier described method with some minor modification^[@CR61]^ ~.~ The 5 μm sections of tissue were deparaffinized overnight (12--15 hr) in xylene and allowed to rehydrate with subsequent changes of the gradient of ethanol (100%, 95%, 70%, and 50%) and distilled water for 10 min with two changes. Antigen retrieval was performed in sodium citrate buffer (10 mM, pH 6) for 20 min followed by the immuno-fluorescence method as described previously^[@CR10],\ [@CR57]^. Tissue sections were further blocked in 5% goat serum for 1 hr and subsequently, after washing with PBS, incubated overnight at 4 °C with the ITGBβ8, and FAK antibodies in 1:100 dilutions and normal rabbit IgG in 1/100 dilutions in 2% goat serum. For the immuno-fluorescence, anti-rabbit FITC conjugated antibody was incubated and counterstained with the Propidium Iodide (PI)^[@CR10]^. Slides containing tissue sections were dehydrated using ethanol gradient (50%, 70%, 90%, 100%) and absolute xylene. Finally, uterine tissue sections were mounted using either DPX or 50% glycerol and the image were captured using a phase contrast inverted phase contrast microscope (CKX41 Trinocular with Cooled CCD Camera Model Q Imaging MP5.0-RTV-CLR-10-C from Olympus, Tokyo, Japan). *ITGB8* esiRNA transfection and FAK activity inhibition in the human endometrial cells (Ishikawa cells) {#Sec20} ------------------------------------------------------------------------------------------------------- Ishikawa cells (Human endometrial adenocarcinoma epithelial cell line) was a kind gift from Dr. Anila Dwivedi, Endocrinology division, (CSIR-CDRI, Lucknow, India) and was maintained in Minimum Essential Medium Eagle supplemented with 1% non-essential amino acids, and 2.2 gm/L sodium bicarbonate and 1% anti-mycotics and antibiotics supplemented with 10% fetal bovine serum. Cells were grown at 37 °C and 5% CO~2~ in humidified condition. JAr cells \[HTB-144, American Type Culture Collection (ATCC), Manassas, VA, USA\], a human choriocarcinoma cell line, were maintained in advanced DMEM/F12 supplemented with 10% FBS and 1% anti-mycotics and antibiotics grown at 37 °C and at 5% CO~2~ concentration in humidified condition. Ishikawa cells were seeded in a 12-well culture plate (\~5 × 10^3^ cells per well) for 12 h in a CO~2~ incubator in humidified condition. The cells were incubated with serum-free media for 4 h before the esiRNA transfection. The esiRNA against *ITGB8* (n = 3) (EHU014221, Sigma-Aldrich Inc.), targeting sequence is, 5′TCCAGAATGTGGATGGTGTGTTCAAGAG GATTTCATTTCAGGTGGATCAAGAAGTGAACGTTGTGATATTGTTTCCAATTTAA TAAGCAAAGGCTGCTCAGTTGATTAAATACCCATCTGTGCATGTTATAATACCCA CTGAAAATGAAATTAATACCCAGGTGACACCAGGAGAAGTGTCTATCCAGCTGCGTCCAGGAGCCGAAGCTAATTTTATGCTGAAAGTTCATCCTCTGAAGAAATATCCTGT3′ or control siRNA (The Sigma-Aldrich MISSION siRNA; Universal Negative Control, SI001.). There was 1 µl of each esiRNA at a concentration of 50 ng/µl and was mixed with 50 µl of Opti-MEM in RNase-free microcentrifuge tube separately. At the same time, a suspension of 1 µl of lipofectamine with 50 µl of OptiMEM in RNase-free tube was prepared and incubated for 20 min at room temperature. Further, the Opti-MEM-esiRNA suspension and lipofectamine-Opti-MEM-suspension were mixed with each other followed by incubation for another 30 min at room temperature and then added to the wells containing a serum free media (900 µl). Cells were incubated with 5% CO~2~ and 37 °C, in humidified condition, for 12 h. Media was changed after 12 h and grown in complete media for another 12 h. For FAK activity inhibition, when the cell reached 60--70% confluence, the cells were treated with FAK inhibitor at a concentration of 30 nM and another 3 wells were served as a control (n = 3). Cells were grown further for 24 h in an incubator with 5% CO~2~ and 37 °C, in humidified condition. After 24 h incubation, the cells were stained with live cell tracker, Cell Tracker Blue CMF~2~HC Dye prepared in PBS for 30 min and it was replaced with DMEM/F-12, without phenol red. *In vitro* embryo implantation by JAr spheroids co-culture on endometrial epithelial cell monolayer {#Sec21} --------------------------------------------------------------------------------------------------- The assay was performed according to the previous method^[@CR62]^. The JAr cells spheroids were prepared in DMEM, F-12 medium. Afterwards, the cells were collected after trypsinization in DMEM/F-12 media and the flask was incubated on dancing shaker with 200 rpm, at 37 °C and at 5% CO~2~ concentration in humidified condition for 12 h. Then spheroids were filtered through 100 µm membrane and the filtrate was re-filtered using 70 µm membrane to collect spheroids having size between 70--100 µm in size. These spheroids were incubated for 10 min with live cell tracker dye Cell Tracker Red CMTPX, and re-suspended in DMEM/F-12, without phenol red. The spheroids were co-cultured on *ITGB8* siRNA, FAK inhibitor or respective control treated monolayer of Ishikawa cells for 10 min and washed with white media/DMEM/F-12, without phenol red and the attached spheroids were counted and imaged using microscope (CKX41 Trinocular with Cooled CCD Camera Model Q Imaging MP5.0-RTV-CLR-10-C from Olympus, Tokyo, Japan). Intraluminal delivery of MO to silence the endometrial *Itgb8* {#Sec22} -------------------------------------------------------------- This is accordance with our earlier published method^[@CR10]^. We received the morpholino oligonucleotides sequence (GGCCGAGCCGCACATAATGCAAAGC, 25 mer) against the mouse *Itgb8* target sequence (in bracket); GGTGCGCTCTCAAGTCGGGAGAGCGCATCAGGAAAGCAACTAGGCAG TAGGCACCGGGCGGGCT\[GCTTTGCATT(ATG)TGCGGCTCGGCC\]CTGGCTTTTC (NM_177290.3, *Mus musculus integrin beta8* (*Itgb8*), mRNA) from Gene Tool, Philomath, OR, USA, which does not overlap with other integrins sequence such as *Itgb*3 or *Itgb6* sequences through BLAST. We have already published one study on this given MO-based silencing of *iItgb8* ^[@CR10]^. The pregnant female mice underwent a mini-laparotomy under anesthesia at day4 (1000 h) of the window of uterine receptivity to deliver the *Itgb8* MO (2 µl of 20 nM) in one of the horn, while the other horn of the same animal (control) received (2 µl of 20 nM) control MO as reported earlier^[@CR10]^. After the Evans blue dye injection, the animals were sacrificed on day5 (1000 h) for the study of embryo implantation sites during post-implantation \[day5 (1000 h)\]. The uterus was photographed to record the number of implanted embryos. Treatment of pregnant mice with FAK inhibitor {#Sec23} --------------------------------------------- The pregnant female mice on the day4 (1000 h) underwent a mini-laparotomy as mentioned in the previous section. One uterine horn of mouse was injected with 2 µl of FAK inhibitor (20 µM) into the lumen through the oviductal site, while another horn was injected with 2 µl of water and served as a control as described elsewhere^[@CR10]^. Implantation sites and inter/non-implantation sites in the uterus were visualized as per earlier mentioned method^[@CR10]^. Delayed implantation mouse model {#Sec24} -------------------------------- We adopted previously described protocol^[@CR57]^ where pregnant female mice were bilaterally ovariectomized on day3 (1600 h) in the presence of anesthetics. Progesterone at 1.0 mg/25 gm of body weight (

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counts/s) was set to 100% and data obtained after 4 min were used for statistical analysis. Note that βγ-meATP produces a small, but significant, slowing of the decay time. (b) Averaged data from the experiments illustrated in (a) are plotted as concentrations of ATP reached in the bath solution immediately after nerve compression (*t* = 0 s) and 4 min later (*t* = 240 s). Compression of spinal roots in the presence of βγ-meATP resulted in higher concentration of ATP and statistically significant slower recovery Discussion {#Sec15} ========== Compression and/or contusion of nerve trunks or spinal roots are common clinical situations with important consequences for nerve function. Previously, changes in electrophysiological parameters of myelinated axons produced by such mechanical stimuli have been studied in detail \[[@CR2]\]. In white matter strips from the ventral spinal cord, it was found that nerve compression produces an immediate, partially reversible decrease of the A fiber compound action potential followed by a persistent conduction block in some of the myelinated axons. These changes in the electrophysiological parameters of A fibers have been also observed in the spinal roots used in the present study (Figures [3](#Fig3){ref-type="fig"} and [7](#Fig7){ref-type="fig"}). The new, additional findings are effects of nerve compression on the concentration of ATP in the extracellular space of an isolated peripheral nerve trunk. Changes in the extracellular concentration of ATP were measured with a time resolution of 1 s. Such online recordings of ATP concentrations were possible because the ATP assay mix was added directly into the organ bath. As described before for epithelia \[[@CR19]\], cultured astrocytes \[[@CR20]\], and postnatal sciatic nerve \[[@CR21]\], the mixture of saline and ATP assay mix was well tolerated by the isolated rat spinal roots used in the present study. The key observation is that nerve compression produces an elevation of the extracellular ATP concentration which returns to the baseline level within a few minutes only. It is very likely that cell lysis contributes to ATP release produced by nerve compression. However, to our knowledge, quantitative aspects and the time course of this type of ATP release are described for the first time. The findings indicate (a) that sufficient ATP is released for activation of axonal P2X receptors and (b) that rapid hydrolysis of ATP may produce enough adenosine for activation of axonal adenosine (A2) receptors. This indicates that chemosensitivity of axons to purines may contribute to the pathophysiology of painful carpal tunnel and other nerve entrapment syndromes. To our knowledge, there is only one previous quantitative report about kinetics of ATP release related to contusion of nervous tissue: Wang et al. \[[@CR24]\] studied the release of ATP following acute impact spinal cord injury. An ATP imaging technique was used to follow ATP release in the setting of this trauma. Imaging was initiated within 10 min after impact, and at this point in time the extracellular concentration of ATP was not elevated in the center of the injury. The authors conclude that ATP released on impact may be hydrolyzed within minutes; our data support this view. A further finding reported by Wang et al. \[[@CR24]\] is a sustained process of pathologically high ATP release in the peritraumatic zone. We do not know whether a similar process takes place in spinal root segments remote from the region of compression because the field of view for the detection of bioluminescence was restricted to the lesion. Our data reveal that compression injury of a peripheral nerve trunk produces high concentrations of extracellular ATP only for an initial transient period. One factor responsible for these fast kinetics may be the in vitro situation which allows rapid diffusion of ATP from the region of nerve compression into the surrounding bathing solution. However, it is also possible that the decline of the ATP concentration is due to extracellular enzymatic degradation and/or consumption by the ATP assay mix. The possible contribution of ATP hydrolysis to the degradation of ATP in isolated spinal roots was studied by means of known inhibitors of ecto-nucleotidases \[[@CR13]\]. One of the compounds used, βγ-meATP, is a potent blocker of ATP hydrolysis by cultured astrocytes \[[@CR20]\]. Also, ARL 67156 is often used as a blocker of ecto-ATPases \[[@CR25]\]. However, application of either compound resulted only in a slight inhibition of ATP hydrolysis by isolated rat spinal roots (see Figure [6](#Fig6){ref-type="fig"}). Also in the isolated rabbit vagus nerve, an incomplete effect of βγ-meATP on ATP hydrolysis has been described \[[@CR15]\]. The reason for these weak effects can be explained in the light of recent findings. It has been described that βγ-meATP preferentially targets the eNPP family of ecto-ATPases (eNPP1 and/or 3) over the CD39 family of eNTPDases \[[@CR22]\]. However, the opposite situation, i.e., a prominent role of eNTPDases for hydrolysis of ATP, seems to be important for peripheral nerve preparations. In particular, the presence of eNTPDase2 was detected on nonmyelinating Schwann cells \[[@CR16]\]. ARL 67156, too, only slightly inhibited ATP hydrolysis by isolated rat spinal roots. This observation is in accordance with the notion that this reagent acts as a modestly efficacious inhibitor of both eNPP and eNTPDase-type nucleotidases \[[@CR22]\]. In a recent study, ARL 67156 revealed the highest inhibitory potency for NTPDase1. It was considerably less effective on NTPDase3 and essentially ineffective on NTPDase2 \[[@CR26]\]. The possible contribution of ecto-nucleotidases for the kinetics of ATP concentration following nerve compression was tested by means of βγ-meATP because this compound was more potent as a blocker of ecto-nucleotidases in spinal roots as compared to ARL 67156. It was observed that βγ-meATP (a) enhanced the compression-induced release of ATP into the bath solution and (b) induced a slowing of the decline in the extracellular ATP concentration in the period following the compression (see Figure [8](#Fig8){ref-type="fig"}). Taken together, these observations indicate that an increase in the extracellular concentration of ATP in the trunk of a peripheral nerve is limited by activity of ecto-nucleotidases. However, at present, a more quantitative analysis is not possible due to the lack of potent inhibitors of such enzymes in peripheral nerve. It is possible that ATP release produced by compression of a peripheral nerve trunk contributes to "positive" symptoms such as the development of pain. However, the concentrations of ATP reached in the extracellular space after nerve injury were only in the nanomolar range (see Figure [4](#Fig4){ref-type="fig"}). Such concentrations of ATP do not activate purinergic receptors in the membrane of nociceptive neurons. However, bioluminescence measured in the present study is mainly induced by ATP in the solution surrounding the nerve trunk. It is very likely that much higher concentrations of ATP are reached in the small extracellular space in the vicinity of nociceptive axons. It has been estimated that only 1% or less of the intracellular ATP pool needs to be released to activate maximally any and all purinoceptors \[[@CR27]\]. In fact, cytosolic ATP released by cell damage produces transient currents in cultured sensory (nociceptive) neurons via activation of ionotropic P2X receptors \[[@CR28]\]. This is an example for a fast functional response due to a transient elevation of extracellular ATP concentration. However, there are several possibilities of how short lasting extracellular ATP transients may induce long lasting alterations in axonal excitability and/or glial activity: (a) degradation of ATP to adenosine could result in an increase of axonal excitability in unmyelinated peripheral nerve fibers via metabotropic A2 receptors \[[@CR7], [@CR18]\]. Production of adenosine from ATP has been shown for isolated vagus nerves \[[@CR15]\] and pain-enhancing actions of adenosine via P1 (A2) receptors have been described \[[@CR5], [@CR17]\]. (b) Long lasting activity in peripheral nociceptive neurons has been discussed as the result of cytokine release induced by activation of purinergic P2X~7~ receptors \[[@CR29], [@CR30]\]. (c) Activation of P2Y receptors on Schwann cells \[[@CR9]--[@CR12]\] may have long lasting consequences similar to the development of P2Y-related gliosis observed in astrocytes \[[@CR31], [@CR32]\]. We would like to thank Ms. Christina Müller for valuable technical assistance and Dr. Uta Rundshagen for help in some of the experiments. This study was supported by the Deutsche Forschungsgemeinschaft (SFB 391/A1). ARL 67156 : 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5-triphosphate βγ-meATP : Adenylylmethylenediphosphonate disodium salt CAP : Compound action potential eNPP : Ecto-nucleotide pyrophosphatase/phosphodiesterase eNTPDase : Ecto-nucleoside triphosphate diphosphohydrolase HEPES : N-(2-Hydroxyethyl)piperazine-N\\prime-(2-ethanesulfonic acid) Work party that is! Our beloved course needs work, and the time is upon us. We are going to be doing work parties on a more regular basis, and this coming week brings the first of many to be had in the near future. Please join us from 9am to 4pm to put some love back into the course. There are nets to be replaced, tanbark to put down

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2d 450 (1960) 239 La. 390 Clarence V. JOHNSON v. James R. WILSON. No. 43867. Supreme Court of Louisiana. February 15, 1960. Rehearing Denied March 21, 1960. *451 Seale, Hayes, Smith & Keogh, Baton Rouge, for applicant. Joseph A. Gladney and J. H. Percy, Jr., Baton Rouge, for respondent. McCALEB, Justice. This suit for damages arises out of an automobile accident occurring at approximately 1:00 p. m. on November 28, 1955, about eight miles north of Baton Rouge on Plank Road, a two-lane two-way hard surfaced highway, when an automobile owned and driven by plaintiff struck a pickup truck owned and operated by defendant. At the time of the accident, plaintiff was attempting to overtake and pass the truck which defendant had edged over the center line of the roadway preparatory to making a left turn onto the premises of his servant. Plaintiff instituted the action to recover damages to his car, amounting to $608.30, charging that the accident was attributable solely to the negligence of defendant. This was denied by defendant in his answer and he, having sustained personal injuries in the accident, reconvened for $235,965.37. He alleged that plaintiff was grossly negligent and, alternatively, pleaded contributory negligence and the doctrine of last clear chance. The case was tried on these issues before a jury and resulted in a verdict for defendant in the sum of $8,507.37. Judgment was rendered in accordance with this verdict and plaintiff appealed therefrom to the Court of Appeal, First Circuit, where the judgment was affirmed. See Johnson v. Wilson, 97 So.2d 674. At plaintiff's instance we granted a writ of certiorari[1] and the case has been argued and submitted for our decision. There is no important disagreement between the parties as to the facts of the case as found by the Court of Appeal. Nor does counsel for plaintiff take serious issue with that court's ruling that plaintiff was guilty of negligence in striking the Wilson car in that he was travelling at a speed in excess of 60 miles per hour (in violation of Section 223 of the Motor Vehicle and Traffic Regulation Statute, R.S. 32:223) and was somewhat inattentive in his driving when he attempted to overtake and pass defendant's truck. On the other hand, counsel proclaimed that the Court of Appeal erroneously exonerated defendant from blame in view of the uncontroverted facts which disclose that defendant violated positive provisions of law, R.S. 32:235(B), in crossing over the center line of the highway in order to negotiate a left turn and that he was also imprudent in pulling into the left lane without looking into his rear view mirror immediately before undertaking such a movement. We think that this complaint is well founded in law. The facts of the case are substantially as follows: At the place of the accident the highway runs relatively straight and flat in both directions. *452 Defendant testified that he was about 500 feet from where he was to turn left into his servant's driveway when he first noticed, in his rear view mirror, the Johnson car which was at that time between one-fourth and one-half a mile behind him; that he was travelling at a speed of 35 miles per hour, so he slowed down, rolled down his window glass and stuck his arm straight out as a signal of his intention to make a left turn; that, when he was 80 to 100 feet from the driveway, he looked in his mirror again and saw the Johnson car 300 to 400 feet behind him; that he never looked back for the overtaking car again and that, when he was 70 feet from the driveway, having meanwhile slowed his speed to 20 miles per hour, he edged over the center line of the highway and began a gradual left turn, believing that the Johnson car would pass him on his right. When defendant's truck reached a point 35 feet from his servant's driveway, the left front wheel was approximately four feet left of the highway center line and the left rear wheel about two feet left of the center line. It was at this point that the right front fender of the Johnson car collided with the left rear fender and wheel of defendant's truck, displacing the wheel and causing the truck to overturn. We think the foregoing facts plainly exhibit that defendant was guilty of negligence which substantially contributed to the accident and but for which the accident would not have happened. However, we intermit our discourse on this subject to dispose of the contention made here, and in the lower courts, by defendant's counsel that plaintiff may not urge contributory negligence because he did not specially plead that defense by way of answer to the reconventional demand. Counsel say that Article 377 of the Code of Practice requires that a plaintiff file written answer to a reconventional demand and that the Court of Appeal, Second Circuit, in Young v. Geter, 174 So. 661 has indicated that whenever a plaintiff relies upon a special defense to defeat a reconventional demand, such defense must be formally pleaded. Counsel's position is not tenable. Article 329 of the Code of Practice declares that when the defendant alleges new facts in his answer "* * * these shall be considered as denied by the plaintiff; therefore neither replication nor rejoinder shall be admitted." Conformably with this article, the Court has held on numerous occasions that, since neither replication nor rejoinder are admitted under our pleadings, the allegations of an answer are open to any objections of law and fact without special plea and that, if the defendant is taken by surprise, the proper remedy is a continuation or a new trial. Patton's Heirs v. Moseley, 186 La. 1088, 173 So. 772; Roy O. Martin Lumber Co. v. Hodge-Hunt Lumber Co., 190 La. 84, 181 So. 865; Lee v. Perkins, 195 La. 939, 197 So. 607; Galiano v. Galiano, 213 La. 332, 34 So.2d 881; Cheramie v. Stiles, 215 La. 682, 41 So.2d 502 and Loew's Inc. v. Don George, 227 La. 127, 70 So.2d 534. Article 377 of the Code of Practice, relied on by defense counsel, provides that reconvention may be pleaded by a defendant either as an exception in his answer to the principal demand or he may institute a distinct and separate demand before the court in which the main demand is pending "* * * and the original plaintiff shall be bound to answer without pleading to the jurisdiction of the court, even, if he has his domicil elsewhere, * * *". The quoted provision that the original plaintiff shall be bound to answer without pleading to the jurisdiction does not mean, as counsel contend, that a written answer shall be filed to the reconventional demand. Hobson v. Woolfolk, 23 La.Ann. 384; Lamorere v. Avery, 32 La.Ann. 1008 and Burge v. Batson, 149 La. 542, 89 So. 687. It simply signifies that the original plaintiff may not question the jurisdiction of the court "* * * even if he has his domicil elsewhere *453 * * *" since he has submitted himself to the court's jurisdiction by filing the original demand. The article must be read in connection with Article 329 of the Code of Practice which prohibits replications and rejoinders and, when thus considered, it cannot be construed (as contended by counsel) to require a formal answer or special plea to a reconventional demand. The statement in Young v. Geter, supra, indicating a contrary view, was wholly unnecessary to the decision of the case and, hence, is to be regarded as pure dictum. Returning, now, to the issue of defendant's contributory negligence, we are convinced that he was imprudent in two particulars which had causal connection with the accident. First, it is shown by defendant's own testimony that, after he had seen the Johnson car 300 to 400 feet behind him and was undoubtedly aware that this car was engaged in an overtaking operation, he edged his truck over the center line and into the left (or passing) lane without looking back again in order to ascertain whether it was hazardous for him to do so.[2] It is seen from the statement of defendant, which we have quoted below in Footnote No. 2, that he felt that, when he had given a hand signal indicating his intention to make a left turn, he was entitled to engage in that maneuver irrespective of the speed of plaintiff's car or the distance of the car from the truck at that time. But, of course, defendant did not have the legal right to commence a left turn by driving over the center line when confronted with an unfavorable traffic condition and, had he checked to his rear, just before turning, he would have realized that the Johnson car was rapidly closing the 300 to 400 foot gap between the car and the truck, which he had previously observed, and prudence would have demanded that he wait until the speeding car either slowed or passed before beginning his angling turn. See Cassar v. Mansfield Lumber Co., 215 La. 533, 41 So.2d 209 and Leonard v. Holmes & Barnes, 232 La. 229, 94 So.2d 241, 242, wherein we approved a ruling of the Court of Appeal that the driver of defendant's truck was negligent "in that he failed to look to his rear just before attempting the lefthand turn, under the well settled law of this state that a person who attempts to make a lefthand turn on a public highway must be sure before doing so that the turn can be made in safety".

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s on her back. I pin her arms to the ground. She stops, glaring up at me. Tears swim in her eyes, reflecting the moonlight. She blinks hard, as if to push back the tears. Our ragged breathing fills the quiet night. “Are you ready to listen to me?” She swallows, and nods. I wait until I feel her body relax beneath mine, then ease my hands off her arms, and unpin her legs from my thighs. Her knee jerks up, toward my groin, and I tilt my hips fast. Christ, she tastes like fire and tears and fear. Her mouth is the most fantastic thing I’ve ever tasted. Her bunched muscles relax beneath my fingers as a whimper rushes through her mouth. Pulling back, I nip her jaw, tracing a path to her ear and running my tongue over its outline. “You taste so damn good, Sophie. Want to kick me again?” She doesn’t answer. I pull back, quirking a brow at her. Fuck, she’s so beautiful with her flushed cheeks and plump, sweet lips. She shakes her head. “Good.” I brush that little dimple on her chin with my fingertips. “Trust. Me.” She bites the corner of her bottom lip and nods. “This talk had better be good, or I might stab you while you sleep.” Book & Author Details: A Need So Insatiable by Cecilia Robert (Hearts #1) Publication date: March 8th 2014 Genres: New Adult, Romance Synopsis: “You’ve owned me from the moment I walked into that music room. You’ve wrapped yourself in my heart and mind. I can’t get you out. I don’t want to.” ~ Rafael Van Rees Sophie Fisher’s life is on fire. If she’s not ducking around corners or slipping out of windows to escape the debt collectors her father’s death has left knocking on her door, she’s dealing with her rebellious, fifteen-year-old sister, Lilli. And, as if that’s not enough, Rafael Van Rees crashes into her life—literally—bringing with him a past the public has no idea of. Can she unravel his mysteries before he unravels her, or will his presence finally force her to face the demons she’s trying to outrun? Rafael Van Rees prides himself on being in control of his destiny, music and women. As far as he is concerned, his past is a black cloud in the distance–until he meets Sophie, that is, and his world spins out of control in more ways than one. He knows the darkest sins and secrets eventually reveal themselves, but when it comes to Sophie, he’ll stop at nothing to protect her from his past. Even if it kills him. I write YA, NA and Adult. My motto: Passion rules. I enjoy writing stories about people finding love in the most unexpected places, coupled with adventurous journeys, whether it's urban, fantasy, sci-fi, contemporary or paranormal romance. There's always a happy ever after, no matter how long it takes to get there. TRADE-IN and get $$$$ New FIRE HD 10 Readsy's Best Book Blog 2017 Sign up for Debra's Newsletter Want to be the first to know about new releases, contests and special deals? Sign up here. * indicates required Email Address * First Name Last Name Email Format html text mobile Search This Blog NetGalley Top Reviewer Review Status CLOSED FOR SUBMISSIONS: I have an overwhelming TBR pile at the moment and am NOT accepting any new books for review. The books reviewed on this site are either digital copies or ARCs sent by publishers or authors. I never accept payment in exchange for a review. Total Pageviews GUEST POSTS ARE WELCOME! If you are interested in contributing a guest post for Two Ends of the Pen, please send me an email at:dlmartin6 AT yahoo DOT com. Your article/post needs to have some relevance to writing, books, ebooks, epublishing, tips for blogging, marketing strategies, etc. You get the idea--really, anything to do with books and being an author in general. I've also highlighted a number of guest posts in the sidebar to help you understand what I'm looking for in a post. I look forward to sharing your posts with my readership. Requesting an Author Interview If you would like to request an author interview, please send an email to dlmartin6 AT yahoo.com and let me know if you are strictly an indie author or an indie/traditionally published author. This way I can send you interview questions to suit your book(s). All the questions are just suggestions, you may add/change/delete any of them. Put "Requesting Author Interview" in the email subject line. Interviews are posted on a first-come first-serve basis and will be posted ASAP depending on the backlog of other posts for the blog. In addition to your interview spotlight page, you will also be added to the list of Author Interviews page. Please do NOT ask me to review your book in your author interview request. I am CLOSED to review submissions. Contact Me If you would like to contact Deb directly, please send a message to:dlmartin6 [at] yahoo [dot] com.News Release Tuesday, April 25, 2017 Attempt Murder Suspect Sought NR17113sr Los Angeles: Detectives from the Los Angeles Police Department's Rampart Area are asking for the public's assistance in identifying attempt murder suspects. On Thursday, December 29, 2016, between 1:50 a.m., and 2:00 a.m., the victims and suspects met inside the Gold Room Bar at 1558 W. Sunset Blvd. The victims and the suspect are observed having drinks together and are captured on the business' security cameras. When the bar closed, the victims and the suspect all left at the same time. The victims and suspect engaged in a verbal dispute. The suspect struck Victim-2 on the side of the head, causing a laceration. Victim-1 tried to keep the peace after the physical altercation and went to talk to the suspect. The suspect then struck Victim-1 with the knife, cutting him on his neck and face. The suspect fled in a dark colored 4 door sedan. The suspect is described as male Hispanic, brown hair, brown eyes, 5 feet 8 inches to 5 feet 10 inches tall, weighing between 200 to 210 pounds, and is 25 to 30 years old. The suspect has a beard and multiple tattoos on his face, neck and head. He was last seen wearing a black jacket with gray pants. Anyone with information about this case is asked to contact Officer Morales, Rampart Gang Detectives, at (213) 484-3660 or (213) 484-3655. During non-business hours or on weekends, calls should be directed to 1-877-LAPD-24-7 (1-877-527-3247). Anyone wishing to remain anonymous should call the L.A. Regional Crime Stoppers at 1-800-222-TIPS (800-222-8477) or go directly to www.lacrimestoppers.org. Tipsters may also visit www.lapdonline.org, and click on "Anonymous Web Tips" under the "Get Involved-Crime Stoppers" menu to submit an online tip. Lastly, tipsters may also download the "P3 Tips" mobile application and select the L.A. Regional Crime Stoppers as their local program.159 F.3d 1357 U.S.v.Kirk* NO. 98-40020 United States Court of Appeals,Fifth Circuit. September 23, 1998 Appeal From: E.D.Tex., No.197CR381 1 Affirmed. * Fed.R.App.P. 34(a); 5th Cir.R. 34-2 Maurya Simon Maurya Simon (born December 7, 1950) is an American poet, essayist, and visual artist. She is the author of ten collections of poetry, including two books that have been nominated for a Pulitzer Prize and a National Book Award. Her most recent volume of poetry is The Wilderness: New and Selected Poems (Red Hen Press, 2018). Early life and education Born in New York City, Simon is the daughter of the Los Angeles visual artist, Baila Goldenthal, and the ethnomusicologist and composer, Robert Leopold Simon. She spent her early years living in Europe with her family, and later moved to Hermosa Beach in southern California, where she lived from 1959–1968. Simon attended the University of California, Berkeley (1968–1971), where she was a student of Robert Gren

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uni-color-subtitle: #555555; // 二级标题颜色 $uni-font-size-subtitle: 36upx; $uni-color-paragraph: #3f536e; // 文章段落颜色 $uni-font-size-paragraph: 30upx; High density lipoprotein cholesterol, total cholesterol and triglycerides in serum after a single exposure to prolonged heavy exercise. Serum high density lipoprotein (HDL) cholesterol, total serum cholesterol and triglycerides were determined in twenty men before, immediately after, and 1, 2 and 4 days after a 70 km cross-country ski race. HDL cholesterol increased by 12% of the pre-race level immediately after the race, rose further to 17% above the initial level on the following day, and was still elevated 4 days after the race. LDL + VLDL cholesterol, however, showed a tendency to decrease immediately after the race and was reduced by 17% and 11% of the pre-race level on the following 2 days. Triglycerides were reduced by 30% of the initial level immediately after the race, were still low on the following day, but were restored to normal 2 days after the race. It is concluded that a single exposure to prolonged heavy exercise induces changes in the HDL metabolism, showing that the physical exercise per se plays an important role for the increased HDL level seen in well-trained athletes.Allow users to remove their own instant invites If a user creates an instant invite to a server, they should be able to remove them with a "remove invite" button or in the dropdown when you would go to notification settings, privacy settings, leave server etc. Reasons why is so if they do not want their invite to exist anymore and don't have access to the server's settings, they can still remove their own invites. (I hope I make sense haha)The Tobacconist (German) UK Jewish Film Festival More information about Release date: 10 November 2019 Running time: 90 minutes Plus short On the Beaches. Bruno Ganz is superb as Sigmund Freud in this heart-rending adaptation of Robert Seethaler's novel. 17-year-old Franz takes up a job at a Viennese tobacconist shop, where he meets the renowned professor. Fascinated by his theories, Franz seeks Freud's advice after falling in love with a dancer. His confusion about love and sex echoes the political turmoil caused by Hitler's imminent annexation of Austria, and Freud's own indecision about leaving the country. This drama sensitively explores its protagonists' longing – for the love of a woman, and for a homeland. Sponsored by: David MondSearch The Independent Inquiry into Child Sexual Abuse Investigating the extent to which institutions have failed to protect children from sexual abuse The Independent Inquiry into Child Sexual Abuse will investigate whether public bodies and other non-state institutions have taken seriously their duty of care to protect children from sexual abuse in England and Wales. Read our Opening Statement and the November update statement. We will identify institutional failings where they are found to exist. We will demand accountability for past institutional failings. We will support victims and survivors to share their experience of sexual abuse. And we will make practical recommendations to ensure that children are given the care and protection they need. The Inquiry is independent of government. The Chair is Professor Alexis Jay OBE, who is supported by a Panel, a Victims and Survivors Consultative Panel, and other expert advisers. More about who we are. Share your experience We are working with victims and survivors who want to assist the Inquiry in its work. You can share your experience of sexual abuse with us. Many victims and survivors have already taken part in the Truth Project and some have asked us to share their feedback on the process. To gain an understanding of the most up to date research on perpetrators of online-facilitated child sexual abuse, we have commissioned NatCen Social Research to undertake a review of published and unpublished literatureWireless communications systems are widely deployed to provide various types of communication content such as voice, video, packet data, messaging, broadcast, and so on. These systems may be multiple-access systems capable of supporting communication with multiple users by sharing the available system resources (e.g., time, frequency, and power). Examples of such multiple-access systems include code-division multiple access (CDMA) systems, time-division multiple access (TDMA) systems, frequency-division multiple access (FDMA) systems, 3GPP Long Term Evolution (LTE) systems, and orthogonal frequency-division multiple access (OFDMA) systems. Generally, a wireless multiple-access communications system may include a number of base stations, each simultaneously supporting communication for multiple mobile terminals. Base stations may communicate with mobile terminals on downstream and upstream links. In some cases, wireless communications systems may not utilize portions of the spectrum because the portions are not big enough to fit a standard waveform. New techniques may be developed to utilize these smaller portions of the spectrum. However, if current systems are scaled, there may be additional issues (e.g., time stretching) that arise.Q: How can I create an Animated Button with a Sprite Sheet using Javascript? I am trying to create an animated button using a sprite sheet. The animation should play on hover and then on mouseout the animation should finish and then stop. How can I go about doing this? I have tried setting the background of a div and controlling the background position through hover events. I can get the background position to set itself properly but each change goes so fast it might as well be instant and so the animation does not show itself. Any suggestions would be helpful. After a lot of searching with no luck I am not sure what else to try. Thank You! A: the best advice would be to use a CSS3. pretty easy no need for javascript: take a look at this for example: http://codeitdown.com/css-sprite-animations/ example here: http://jsfiddle.net/drukaman/ued7mLha/1/ An Unschooling Manifesto - jlhamilton http://blogs.salon.com/0002007/2009/04/25.html#a2369 ====== 3pt14159 I was home schooled for grade 2 and 3 and private schooled the rest. Throughout that whole period my best years of learning were grades 11 and 12. The reason for this was that during all other private school years I was forced to sit and trod through material that was far too easy. I never did the homework because I could still pull of 70s and didn't see the value in having a higher grade. I was invited to province wide math contests, but was only scoring 72% in math. Finally my math teacher in grade 11 asked me how this could be. (He also happened to be the vice principal) I told him clearly: I hate class and I hate homework. They are not challenging, so I refuse to put effort into them. He suggested the exact same thing that article advocated. The change was immediate. By grade 12 I was scoring 97 in calculus, 95 in linear algebra and 92 in finite math. All because I could move at my own pace. When I had exhausted the course material my teacher gave me books like Aristotle's mathematical proofs. These changed my life. Imagine if this type of freedom had been available my whole life. My parents tried when I was young (via homeschooling) but my social development suffered too much and I wasn't getting the passion for the subjects that teachers can impart. If I were to raise children now I would insist on a school that used the <http://en.wikipedia.org/wiki/Montessori> style. It might not be the best for everyone, but for even slightly gifted children I think it will drastically improve their mental growth. ~~~ stanleydrew I think Montessori is unbelievable. I went to a Montessori school through third grade and loved it. But I don't think it works for everyone. My brother didn't enjoy it or do as well in the unstructured environment as I did. So I think multiple kinds of education are necessary. The problem is that there's a lack of information about education options for most people. And perhaps an issue of affordability. You might say that the public school system ought to offer alternatives to the structured model. And maybe it should. I don't know how much that would cost. But I'm sure a lot of people would take advantage of it. ~~~ jacoblyles One of the great things about the market model is decentralized choice. Nobody has to decide what choices are offered for everybody. That decision is between the consumers and the producers. And private school voucher programs that currently exist cost as little as 25% of the cost of educating that same child in public school. ------ jgilliam My parents tried to home school me in the late 80's, early 90's (they were very religious). It turned into unschooling, because I was able to plow through the "curriculum" in very little time, and then spent all the rest of my time online. My dad worked for IBM so we had computers around, but when I found out that computers could _talk_ to each other, I fell

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production until the end of the war, although the Jagdpanzer IV and Panzer IV/70 took priority. The Hornisse made its first appearance at Kursk. Its powerful and long-ranged 88mm gun meant it could kill Soviet tanks at great distances – this helped cancel out the risks caused by its high profile and light armour. These Hornisse belong to the 519th Heavy Panzerjäger Battalion serving on the Eastern Front in the winter of 1944. This was one of six such battalions equipped with this Panzer IV-based tank destroyer. A Panzer IV Ausf H on the Eastern Front with its Schürzen intact. It bears the tactical number '505' and has a two-tone camouflage scheme. Hummel belonging to the 1st SS Panzer Division being transported by rail. Tarpaulins have been fitted to keep the rain out of the fighting compartment. The key and shield divisional insignia can just be seen on the front of the superstructure on the right-hand side. ## Chapter Nine ## Beyond the Seine The Panzer IV played a significant part in the Battle for Normandy. The most common type of panzer resisting the Allies in occupied France in 1944 was the Panzer IV Ausf H and Ausf J totalling around 750 tanks. Around two-thirds of the Panzer IV battalions were armed with the Ausf H and the rest with the newer Ausf J. With frontal armour of 80mm and the 75mm KwK 40 L/48 anti-tank gun, the Panzer IV provided the fighting backbone of the ten panzer divisions deployed to France (in all five army and five Waffen-SS divisions fielded it in Normandy). It, along with the Panther and Tiger tanks, gave the Germans a distinct advantage in tank-to-tank engagements during the battles in the Normandy bocage. Notably its gun had a 20 per cent higher muzzle velocity than that of the ubiquitous American-built M4 Sherman's 75mm gun, meaning it could punch through 92mm of armour at 500 yards, while the Sherman could only manage 68mm. In addition the Panzer IV proved remarkably reliable, maintaining consistently good operational rates. Normally the Panzer IV was allocated to the 2nd Battalion or II Abteilung of a panzer regiment, while the 1st was equipped with the Panther, although there were a number of exceptions in France. In the case of the 9th Panzer Division the 1st Battalion of its Panzer Regiment 33 was equipped with Panzer IVs and both battalions of 21st Panzer's Panzer Regiment 22 were equipped with it. At the beginning of June 1944 the 2nd Panzer Division, deployed east of the Seine at the start of the campaign, had a total of ninety-eight Panzer IVs on its strength. By early July the division still had eighty-five of them in the field with another eleven in the workshop. The 9th Panzer Division, based in the south of France, arrived in the Normandy in early August with a total of eighty-two Panzer IVs. The 21st Panzer Division, already in Normandy from the start, had a total of 104 Panzer IVs, including six old Ausf G and six even older Ausf B or C with the short 75mm gun. None of the latter seems to have been upgraded and lacked Zimmerit and Schürzen. Before D-Day one of the Ausf B/C dubbed 'Heidi' was photographed in St Martin de Fresnay, south-east of St Pierre-sur-Dives, where its crew were happily shopping for Camembert cheese. It is not clear if this was an authorized use of official military equipment or simply a PR exercise. On 24 May 1944 another fourteen Panzer IVs were despatched to 21st Panzer, but it is unlikely that they had arrived by early June. During the battle for Normandy another thirty were sent to the division including three command tanks. The final ten gun tanks probably did not arrive in time to take part in the fighting. Panzer Lehr Division, initially north-west of Orleans, had ninety-nine Panzer IVs. It was sent another eleven Mk IVs as replacements on 8 July 1944. Following heavy fighting with the Americans, by 22 August the division had just ten left. When the 116th Panzer Division Windhund, north of Paris, was committed to the battle for Normandy in late July it had 86 Panzer IVs. Its other armoured fighting vehicles include three older Panzer IVs with the short 75mm gun. Following the German retreat and the fighting at St Lambert the division was only able to retrieve four Panzer IVs from the battlefield. The Waffen-SS panzer divisions committed to Normandy were also equipped with the Panzer IV. The 1st SS Panzer Division Leibstandarte Adolf Hitler, east of Brussels, mustered forty-two Panzer IVs in its 1st Tank Battalion. A further eight were in for repair. Deliveries during June amounted to another fifty-three tanks. After being sent to Normandy by late July the division was able to field sixty-one Panzer IVs. The 2nd SS Panzer Division Das Reich by the beginning of June had fifty-four Panzer IVs, of which ten were in the workshop. Further deliveries of armour meant that the 2nd SS was to field a total of eighty-three Panzer IVs, which included the newer Ausf J. Many of these were lost in the Roncey pocket at the end of July, though some of the Mk IVs from 2nd SS managed to escape. The 9th SS Panzer Division Hohenstaufen had forty-eight Panzer IVs at the start of the campaign, but seven of these were in the shop. Its sister division 10th SS Frundsberg was able to deploy thirty-nine and by mid-August had only lost twelve. However, just eight Panzer IVs were available to hold the Americans at bay. The formidable 12th SS Hitlerjugend had an authorized strength of 101 Panzer IVs though only ninety-one were combat ready. By 10 August after much heavy fighting the division had just fifteen left. By 1944 the panzer divisions were largely relying on flak guns mounted on half-tracks for air defence, including the SdKfz 10/4 and SdKfz 7/1. In Normandy the Flakpanzer 38(t) using Czech-built chassis was in service instead of the Flakpanzer IV with the 2nd, 9th, Panzer Lehr and 1st SS Panzer Divisions. In theory eight Flakpanzer IV Möbelwagen were allocated to the anti-aircraft section of a panzer regiments headquarters' company. In July 1944 (on paper at least) Möbelwagens were assigned to the 12th SS and 116th Panzer Divisions. Very limited numbers of Wirbelwind also saw combat in Normandy. The lack of infantry divisions, which were held north of the Seine, meant the panzers bore the brunt of the fighting. By the beginning of July 1944 the unrelenting operational commitment of the panzers had taken its toll: 42 per cent of the Panzer IVs and 58 per cent of the Panthers were in the maintenance depots. Prior to Montgomery's Goodwood offensive on 18 July Panzer IVs of 21st Panzer along with Tiger tanks from Heavy Panzer Battalion 503 were caught in the Allied saturation bombing near Château de Manneville 10km east of Caen. The effects were devastating, with tanks simply tossed upside-down like they were toys. From a force of about fifty panzers over half were lost, many others suffering mechanical failures. Although Goodwood failed to breakthrough the incredibly tough German defences it contributed further to the attrition of the Panzer IVs in Normandy and helped pin them in the British sector. In August for the renewed counter-attack at Mortain against the Americans the Germans could only gather seventy-seven Panzer Mark IVs and forty-seven Panthers, roughly the same inadequate number that had been launched in the initial attack, which involved fifty-seven Panzer IVs and seventy Panthers. A few weeks later, unable to contain the American breakout, the German Army was in headlong flight and then trapped at Falaise and defeated. After the Battle for Normandy despite the presence of surviving panzers belonging to the SS at Arnhem, Montgomery was not put off launching Operation Market Garden that resulted in the disastrous battle for the Rhine crossing. Following the Panzerwaffe's mauling in Normandy by late 1944 the Panzer IV was in very short supply. As a result of continual battlefield attrition and the disruption caused by Allied bombing the panzer divisions struggled to field both a battalion of Panzer IVs and a battalion of Panthers. The 2nd and 11th Panzer and the 2nd SS and 9th SS Panzer Divisions each had two companies of StuG assault guns instead of Panzer IVs; the 9th and 116th Panzer Divisions had no Panzer IV at all, fielding instead three companies of StuGs. Other divisions had a single battalion of mixed Panzer IVs and Panthers. The second battalion had to be substituted by panzerjäger and sturmgeschütz units. To make up for such shortfalls, prior to Hitler's winter Ardennes offensive the 1st SS was supplemented by a battalion of heavy Tiger IIs, while the other divisions had to

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additional cases were reported in the past 24 hours, putting Italy’s total case count at 86,498. Lombardy region and Emilia Romagna remain the hardest hit regions with 37,298 and 11,588 cases, respectively. There are 36,653 cases in home isolation, 26,029 hospitalized cases and 3,732 required intensive care. In related news, the International Olympic Committee and the Tokyo 2020 Organizing Committee announced that the Games of the XXXII Olympiad in Tokyo will be rescheduled to a date beyond 2020 but no later than summer 2021. Globally to date, more than 585,000 cases have been reported from 176 countries or regions and nearly 27,000 deaths have been recorded.Orbis, Rhineland-Palatinate Orbis is a municipality in the Donnersbergkreis district, in Rhineland-Palatinate, Germany. References Category:Donnersbergkreis Category:Palatinate (region)Ferrari Ignites Bologna - Web Exclusive The Bologna Motor Show in Italy came to life this week to the sound of a Ferrari F1 car. Fans of the team were able to see the car in action at the 37th annual auto show that features a number of motorsport legends. This year Giancarlo Fisichella drove the 2009 F60, which Fisichella drove that year when he stood in for the injured Felipe Massa. The driver and car got a warm welcome from the fans packing the grandstands despite the freezing conditions. Fisichella, who won this year's FIA World Endurance Championship alongside Gimmi Bruni in a Ferrari 458 GT2, also did four pitstop simulations for the spectators to enjoy. TEXAS COURT OF APPEALS, THIRD DISTRICT, AT AUSTIN NO. 03-13-00338-CV In re Eric Flores ORIGINAL PROCEEDING FROM TRAVIS COUNTY MEMORANDUM OPINION Relator Eric Flores, an inmate, has filed a pro se petition for writ of mandamus, asking this Court to compel an unspecified Travis County District Court to appoint a medical expert in an administrative proceeding that Flores has filed with the Texas Medical Board. The proceeding involves a claim by Flores that certain autopsy procedures conducted by the El Paso County Medical Examiner’s Office are illegal. Mandamus is an extraordinary remedy that issues only to correct a clear abuse of discretion or violation of a duty imposed by law when no other adequate remedy at law is available. See Walker v. Packer, 827 S.W.2d 833, 839 (Tex. 1992); Johnson v. Fourth Court of Appeals, 700 S.W.2d 916, 917-18 (Tex. 1985); State v. Walker, 679 S.W.2d 484, 485 (Tex. 1984). The relator has the burden to provide the Court with a record sufficient to establish his right to mandamus relief. See Walker, 827 S.W.2d at 837. Flores has failed to demonstrate that he is entitled to the extraordinary relief sought. See id. at 837-44. Accordingly, the petition for writ of mandamus is denied. See Tex. R. App. P. 52.8(a). __________________________________________ Bob Pemberton, Justice Before Justices Puryear, Pemberton and Rose Filed: June 7, 2013 2 The Venus Express spacecraft has spent eight productive years orbiting the planet Venus and is now ready to take the plunge. Its orbit is slowly being lowered and from Wednesday it will repeatedly dive in and out of the planet’s dense and harsh atmosphere, travelling deeper than it ever has before. It’s not known whether the spacecraft will survive the soaring temperatures or if its electrical components will be able to handle the strain. But whatever the outcome, valuable data will be obtained by the spacecraft’s engineers to help inform future planetary missions, along with a rare opportunity to investigate a previously unexplored territory of Venus. Time to take a chance Venus Express is the European Space Agency’s first mission to Venus and is currently the only spacecraft studying that planet, the second from our sun. It entered orbit in April 2006 for a mission that was due to last 500 days, or just over two Venus days as measured by the planet’s very slow rotation. After all this time – and a number of successful mission extensions – the spacecraft’s fuel gauge is now close to empty. So ESA has seized the opportunity to push the spacecraft into new territory. It will be sent to plough through the atmosphere of Venus to demonstrate the techniques of aerobraking – using a planet’s atmosphere to slow down a spacecraft. It’s a useful manoeuvre for getting into orbit around a planet without heavy reliance on rocket engines, which would require packing lots of fuel on board and increases the power needed to launch off Earth. Swinging high and swinging low It takes 24 hours for Venus Express to complete one highly elliptical orbit. The spacecraft soars 66,000km above the planet’s south pole before swinging around to skim the upper atmosphere just a few hundred kilometres above the north pole. After completing 500 days in orbit, Venus Express had mapped the entire planet twice over. The second pass filled in important data gaps missed the first time around and showed how things had changed from one long Venus day to the next. During this period, the spacecraft maintained a height between 250km to 400km above the north pole. To open up new science opportunities and extend the work of the spacecraft beyond its primary mission, its orbit was cautiously lowered to between 185km and 300km, in the first atmospheric drag experiment (ADE). This placed Venus Express in reach of the upper atmosphere of Venus. And on August 4, 2008, the spacecraft did indeed feel the effects and experienced a low level of atmospheric drag for the first time. Pedalling against sunlight Since then, over a dozen ADEs have been carried out, each one following a similar pattern. Venus Express is low on fuel because it routinely needs a boost to maintain its orbit. If left alone, the orbit falls into a natural decay which lowers the spacecraft towards the north pole by as much as 4km in each successive orbit. A number of factors are involved but the main effect is due to solar radiation. Sunlight is known to exert pressure – it’s the reason why comet tails always point away from the Sun. So when Venus Express travels towards the incoming solar radiation its orbital speed is reduced, just like trying to ride a bicycle into a headwind. At such times, the spacecraft’s orbit drops most quickly towards the north pole. ESA But at other times, Venus Express travels across the solar radiation, or in other words our cyclist pedals against a crosswind. This is relatively easier to manage. The spacecraft doesn’t slow down by as much and its descent towards the north pole is briefly stabilised. When this occurs, it’s the perfect time to hold off any orbital boosts and allow the spacecraft to slowly and carefully dip into the atmosphere. The spacecraft is the experiment The ADEs were perfect dress rehearsals for the major event occurring this week. During each one, Venus Express dipped into the atmosphere for just six minutes of its 24-hour orbit, and would repeat this for around ten days. On three occasions it dropped as low as 165km above the north pole, reaching into the upper ionosphere. Venus Express does not include an instrument capable of measuring the density of the atmosphere. Instead it uses its own reaction to the atmospheric drag it encounters. During the ADEs, the spacecraft’s two solar panels are oriented asymmetrically, so that one faces the incoming stream of atmosphere, while the other is turned by 90 degrees and presents itself edge on. As it’s buffeted by the weak atmosphere, the spacecraft experiences a torque. Stabilising reaction wheels work to compensate and maintain the spacecraft’s orientation. Just how much adjustment is needed translates into quite a precise estimate of the atmosphere’s density. Furthermore, the spacecraft’s trajectory is also meticulously tracked so that any changes brought about by atmospheric drag can also be determined and turned into a measure of density. Australia listens in In all previous ADEs, the safety of Venus Express has been paramount and the spacecraft was closely monitored by the two ground stations in the right location to track it at those critical moments: ESA’s New Norcia station in Western Australia and NASA’s Deep Space Network in Canberra. During an ADE, calculations would be made daily to determine the unique escape manoeuvre that would get Venus Express out of a bind and immediately raise its orbit. Venus Express was not allowed to experience levels of atmospheric drag that might comprise its safety. But that’s about to change – it’s now or never for Venus Express. Cloudy with a chance of annihilation Science operations concluded on May 16 and since then the orbit of Venus Express has been left to decay and should stabilise at around 130km by Wednesday, June 18. If it survives it will be boosted back to an altitude of 475km in mid-July. But that will be it for fuel reserves and

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}^{(j)}(\theta)&=&\Big|d_{m',m}^{(j)}(\theta)\Big|^2.\end{aligned}$$ We shall use the map of numbers $m'$ and $m$ onto the numbers $1,2,\ldots,N$, $N=2j+1$ using the following rule $-j\Rightarrow 1,\quad -j+1\Rightarrow 2,\quad\ldots,\quad j \Rightarrow N.$ Thus, we can study the relation which can be obtained by considering the probability vector $\overrightarrow{p}=(p_1,p_2,\ldots,p_N)$, where $\sum\limits_{k=1}^{N}p_k=1$, $p_k\geq0$ hold. Hence, similarly to Sec. \[sec:1\] we can denote as $\widetilde{m}_{ik}$, $i,k\in\{1,2,\ldots N\}$. Fixing the index $k$ and mapping the index $i$ onto pairs $(\alpha(i),\beta(i))$ as in or we can write the entropy of the whole system in terms of $\widetilde{m}_{ik}\equiv\widetilde{p}_{\alpha(i),\xi(i)}^{(k)}$, i.e. $$\begin{aligned} \widetilde{\mathcal{H}}_{m}(12)&=&-\sum\limits_{\alpha=1}^{2}\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{\alpha(i),\xi(i)}^{(k)}\ln \widetilde{p}_{\alpha(i),\xi(i)}^{(k)}\\ &=&-\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\left(\widetilde{p}_{1,\xi(i)}^{(k)}\ln \widetilde{p}_{1,\xi(i)}^{(k)}+\widetilde{p}_{2,\xi(i)}^{(k)}\ln \widetilde{p}_{2,\xi(i)}^{(k)}\right)\\ &=&-\sum\limits_{i=1}^{N(N+1)}\widetilde{m}_{ik}\ln \widetilde{m}_{ik}\\ &=&-\sum\limits_{m'=-j}^{j}\Big|d_{m',m}^{(j)}(\theta)\Big|^2\ln \Big|d_{m',m}^{(j)}(\theta)\Big|^2.\end{aligned}$$ Analogically, the partial entropies can be written as $$\begin{aligned} \widetilde{\mathcal{H}}_{m}(1)&=&-\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{\xi(i)}^{(k)}(1)\ln \widetilde{p}_{\xi(i)}^{(k)}(1)\\ %&=&-\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\left(\widetilde{p}_{1,\xi(i)}^{(k)}+\widetilde{p}_{2,\xi(i)}^{(k)}\right)\ln \left(\widetilde{p}_{1,\xi(i)}^{(k)}+\widetilde{p}_{2,\xi(i)}^{(k)}\right)\\ %&=&-\sum\limits_{i=1}^{N(N+1)}\left(\widetilde{m}_{ik}+\widetilde{m}_{i+\frac{N+1}{2},k}\right)\ln \left(\widetilde{m}_{ik}+\widetilde{m}_{i+\frac{N+1}{2},k}\right)\\ &=&-\sum\limits_{m_1'=-j}^{-\frac{1}{2}(0)}\sum\limits_{m_2'=\frac{1}{2}(1)}^{j}\left(\Big|d_{m_1'm}^{(j)}(\theta)\Big|^2+\Big|d_{m_2'm}^{(j)}(\theta)\Big|^2\right)\\ &\cdot&\ln \left(\Big|d_{m_1'm}^{(j)}(\theta)\Big|^2+\Big|d_{m_2'm}^{(j)}(\theta)\Big|^2\right),\end{aligned}$$ $$\begin{aligned} &&\widetilde{\mathcal{H}}_{m}(2)=-\sum\limits_{\alpha=1}^{2}\widetilde{p}_{\alpha(i)}^{(k)}(2)\ln \widetilde{p}_{\alpha(i)}^{(k)}(2)\\ %&=&-\widetilde{p}_{1}^{(k)}(2)\ln \widetilde{p}_{1}^{(k)}(2)-\widetilde{p}_{2}^{(k)}(2)\ln \widetilde{p}_{2}^{(k)}(2)\\ %&=&-\left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{1,\xi(i)}^{(k)}\right)\ln \left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{1,\xi(i)}^{(k)}\right)\\ %&-&\left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{2,\xi(i)}^{(k)}\right)\ln \left(\sum\limits_{\xi=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{p}_{2,\xi(i)}^{(k)}\right)\\ %&=&-\left(\sum\limits_{i=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{m}_{ik}\right)\ln \left(\sum\limits_{i=1}^{\frac{N}{2} (\frac{N+1}{2})}\widetilde{m}_{ik}\right)\\ %&-&\left(\sum\limits_{i=\frac{N}{2}+1 (\frac{N+1}{2}+1)}^{N (N+1)}\widetilde{m}_{ik}\right)\ln \left(\sum\limits_{i=\frac{N}{2}+1 (\frac{N+1}{2}+1)}^{N (N+1)}\widetilde{m}_{ik}\right)\\ &=&-\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}\Big|d_{m',m}^{(j)}(\theta)\Big|^2\ln\left(\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}\Big|d_{m',m}^{(j)}(\theta)\Big|^2\right)\\ &-&\sum\limits_{m'=\frac{1}{2}(1)}^{j}\Big|d_{m',m}^{(j)}(\theta)\Big|^2\ln\left(\sum\limits_{m'=\frac{1}{2}(1)}^{j}\Big|d_{m',m}^{(j)}(\theta)\Big|^2\right).\end{aligned}$$ The subadditivity condition for the matrix from the $SU(2)$-group is the following $$\begin{aligned} \label{15}&-&{\sum\limits_{m_1'=-j}^{-\frac{1}{2}(0)}\sum\limits_{m_2'=\frac{1}{2}(1)}^{j} \Bigg(S_{m_1',m}^{(j)}(\theta)P_{m_1',m}^{(j)}(\theta)^2+S_{m_2',m}^{(j)}(\theta)P_{m_2',m}^{(j)}(\theta)^2\Bigg)}\ln \left(S_{m_1',m}^{(j)}(\theta)P_{m_1',m}^{(j)}(\theta)^2 +S_{m_2',m}^{(j)}(\theta)P_{m_2',m}^{(j)}(\theta)^2\right)\\\nonumber &-&\!\!\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2 \ln\left(\sum\limits_{m'=-j}^{-\frac{1}{2}(0)}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\right)-\!\!\!\!\sum\limits_{m'=\frac{1}{2}(1)}^{j}\!\!\!\!S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\ln \left(\sum\limits_{m'=\frac{1}{2}(1)}^{j}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\right)\\\nonumber &\geq&-\sum\limits_{m'=-j}^{j}S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\Bigg(\ln\left(S_{m',m}^{(j)}(\theta)P_{m',m}^{(j)}(\theta)^2\right)\Bigg).\end{aligned}$$ The resulted inequality can be interpreted as the new inequality for the Jacoby polynomials. Examples of systems with spins $j=3/2$ and $j=2$ ------------------------------------------------ Let us consider the state with the spin $j=3/2$. As an example we take $m=3/2$. Hence, the partial entropies are determined by $$\begin{aligned} \widetilde{\mathcal{H}}_{3/2}(12)&=&-\sum\limits_{t=1}^{4}(p_t(\theta)\ln(p_t(\theta)),\\ \widetilde{\mathcal{H}}_{3/2}(1)&=&-((p_3

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low that I wasn't sure if he was talking to me or to himself. I waited, stirring the pan as the milk began to simmer, and figured that if it _were_ me he was talking to, he'd let me know when he wanted an answer. "I thought that I knew her... and the woman that I loved would not have betrayed me so willingly." I took two white china cups and saucers from the cabinet and poured some milk into each one. "Maybe her need for revenge was greater than her need for human love," I said softly. "I do not think so," Senenmut said gravely, looking up at me for the first time. I didn't answer as I stirred a couple of spoonfuls of cocoa powder into one of the cups of milk and set it in front of him. I did the same for myself, then took the stool beside him. "Maybe you just didn't know her as well as you thought you did," I said, taking an exploratory sip of my drink—which was delicious—and trying not to burn the roof of my mouth at the same time. Senenmut watched me sip my drink, then looked down at his own cup of hot chocolate. "You said I could try yours first." I shrugged. "I lied. It's cocoa. I promise you you're not gonna want to share it, either." This made Senenmut smile, but only for a moment, then the smile disappeared as quickly as it had come. "Do you really believe that it is a good idea to bring Hatshepsut and her Minx to your home?" Senenmut asked, sniffing the cup of cocoa curiously before sipping it. "I don't think I have any choice," I said. "I either confront them here, where I have a little support, or at my tiny apartment, where I don't." Senenmut nodded and took another sip of cocoa. "This is very good." "Cocoa's the one thing I'm pretty good at not screwing up," I replied, pleased that Senenmut liked my little hot chocolate pick-me-up. We sipped our drinks in silence, each lost in our own thoughts. It was really nice not to be alone as I waited for Clio and Jarvis to summon Hatshepsut and her Minx. Out of nowhere, Senenmut said, "Do you trust Bast?" I picked up my cup and drank what was left of my hot chocolate then I stood up to put my cup and saucer into the sink. "No, I think she's up to something—and I also think she's got some kind of weird hold over Jarvis and my sister." Senenmut nodded. "Yes, I think that you are right, only—" He paused, thinking. "What? Go on," I said. Senenmut shook his head. "It may be nothing—" he started to say, but was interrupted by a faint knocking sound. Startled, I turned around to find Clio standing at the window in front of the kitchen sink, gesturing for us to come outside. "I think it's time," Senenmut finished instead, leaving me to wonder exactly what it was he was going to say before Clio interrupted him. As we left the safety of the kitchen—and the comfort of our hot chocolate—my Egyptian friend's comment about Bast stayed with me, scratching at my brain like an itch that wouldn't go away. **twenty-six** Clio was unusually quiet as Senenmut and I followed her across the grounds toward the cliff's edge, the roaring of the waves below us like white noise in my head. I guessed everyone was feeling kind of tense, because the usual joking banter Clio and I would've fallen into was replaced by silence as we moved toward the benches. I wrapped my arms around myself, my mohair sweater not even pretending to keep me warm. I realized I should've grabbed a jacket before we went outside, but I didn't think anyone would take too kindly to me running back to get one. It was already cold out—and the buffeting winds only made it worse, whipping the longer strands of my hair into my face, stuffing my mouth with the foul taste of dog drool and sweat. _Yuck!_ The only light came from the fullness of the moon, which hung round and distended above us, making me wonder what exactly it was we were about to give birth to by inviting Hatshepsut and her Minx to Sea Verge. Even though he _was_ acting kind of weird, I trusted Jarvis implicitly, and since he had signed off on the experiment, I wasn't worried about biting off more than we could chew. Still, once they _did_ arrive—and under false pretences, mind you—how they heck were we gonna contain them? The Minx in its Mustafa form had already proven to be a wily adversary—and I didn't know _what_ Hatshepsut would do once she laid eyes on her long-lost lover, Senenmut. Things could go to Hell in a handbasket pretty damn quickly if we weren't careful. Senenmut took my hand as we got closer to the cliff's edge—and my first thought was that he was just being friendly—but when he gave my fingers a metacarpal-crushing squeeze, I had to stifle a yelp. I looked over at him angrily, not sure what game he was playing at, but he merely shook his head, his eyes wide with fear. He indicated with his head, and I followed his gaze. Jarvis and Clio had encircled the benches with a fine white powder that I couldn't place but guessed was crushed bone. "What is it?" I hissed at Senenmut, but he only squeezed my fingers harder to shut me up as Clio turned to see what the trouble was. I flashed her a wide smile, which she seemed to accept. "All good," I said. "Just tripped over myself for a minute there." This got another harsh squeeze from Senenmut, who had slowed his pace down to half speed, pulling me with him as he decelerated. "Fine," I mumbled under my breath. "Don't tell me what's going on." But by then, I was starting to feel kind of nervous about the scene that lay ahead of us, too. I spied Jarvis standing just within the circle of bone powder over by the cliff's edge, Bast sitting primly on his shoulder. That was so _not_ a Jarvis move. Still, even with my growing misgivings, I forged ahead, glad that I at least had Senenmut in my corner. "What's with the circle?" I asked Clio as we neared our destination. "It's for the spell, silly girl," Clio replied. Her voice was light, but it worried me that she chose not to turn around and look at me when she spoke. Besides which, what seventeen-year-old girl living in the twenty-first century _ever_ used the term "silly girl" in reference to an older sibling? I would've expected that kind of terminology from Jarvis, but Clio? _Never_ —no matter _how_ many Paris Hilton reality shows she decided to watch. "I've never done a summoning spell before," I said, "but it seems kind of weird to have to use ground-up bones just to make what amounts to a toll-free long-distance call." Senenmut and I had reached the edge of the circle, but instead of following Clio inside it, we had each made an unconscious decision to stay as far away from the bone meal-covered part of the ground as possible. "You have to step inside the circle for the spell to work, Callie," Clio said, beckoning me forward. "I don't think so," I replied, my feet staying firmly where they were. "Why not, Calliope?" Jarvis said—using my given name again—as he reached up to stroke Bast's neck. "The spell won't work if you don't step into the circle." "Step into the circle," Clio said, more resolutely. "Yes, step into the circle," Jarvis chimed in. "Would you guys _please_ stop with all the repeating," I groaned. "You're giving me a headache." Senenmut squeezed my hand again, forcing me to look away from Clio and Jarvis. "What?" I hissed, annoyed. "Don't look them in the eye," he whispered. "Why?" He sighed. "You ask too many questions, Calliope Reaper-Jones. Just... don't do it." "Fine," I said, exasperated. Out of the corner of my eye, I saw Clio lean forward to whisper into Jarvis's ear. "Whatcha talking about?" I asked innocently, and they both quieted down instantly. I waited for one of them to answer me, but neither of them seemed inclined to speak. In the end, it was Bast

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Conference (MVMC) Ohio-Kanawha Valley Conference (OKVC) Potomac Conference (PC) Camps The West Virginia - Western Maryland Synod assists three camps: Camp Luther -- located at Camp Caesar in Cowen, West Virginia Caroline Furnace Lutheran Camp & Retreat Center -- in Fort Valley, Virginia Camp Melancthon --located at New Germany State Park in Grantsville, Maryland See also List of ELCA synods References External links Synod website Category:Evangelical Lutheran Church in America synods Category:Lutheranism in Maryland Category:1988 establishments in the United States--- abstract: 'We study the parameterized and classical complexity of two problems that are concerned with induced paths on three vertices, called $P_3$s, in undirected graphs $G=(V,E)$. In <span style="font-variant:small-caps;">Strong Triadic Closure</span> we aim to label the edges in $E$ as strong and weak such that at most $k$ edges are weak and $G$ contains no induced $P_3$ with two strong edges. In <span style="font-variant:small-caps;">Cluster Deletion</span> we aim to destroy all induced $P_3$s by a minimum number of edge deletions. We first show that <span style="font-variant:small-caps;">Strong Triadic Closure</span> admits a $4k$-vertex kernel. Then, we study parameterization by $\ell:=|E|-k$ and show that both problems are fixed-parameter tractable and unlikely to admit a polynomial kernel with respect to $\ell$. Finally, we give a dichotomy of the classical complexity of both problems on $H$-free graphs for all $H$ of order at most four.' author: - Niels Grüttemeier and Christian Komusiewicz title: 'On the Relation of Strong Triadic Closure and Cluster Deletion[^1]' --- Introduction ============ We study two related graph problems arising in social network analysis and data clustering. Assume we are given a social network where vertices represent agents and edges represent relationships between these agents, and want to predict which of the relationships are important. In online social networks for example, one could aim to distinguish between close friends and spurious relationships. Sintos and Tsaparas [@sintosL] proposed to use the notion of strong triadic closure for this problem. This notion goes back to Granovetter’s sociological work [@Granovetter73]. Informally, it is the assumption that if one agent has strong relationships with two other agents, then these two other agents should have at least a weak relationship. The aim in the computational problem is then to label a maximum number of edges of the given social network as strong while fulfilling this requirement. Formally, we are looking for an *STC-labeling* defined as follows. A *labeling* $L=(S_L,W_L)$ of an undirected graph $G=(V,E)$ is a partition of the edge set $E$. The edges in $S_L$ are called *strong* and the edges in $W_L$ are called *weak*. A labeling $L=(S_L,W_L)$ is an *STC-labeling* if there exists no pair of strong edges $\lbrace u, v \rbrace \in S_L$ and $\lbrace v, w \rbrace \in S_L$ such that $\lbrace u, w \rbrace \not \in E$. For any weak (strong) edge $\lbrace u, v \rbrace$ we refer to $u$ as a weak (strong) neighbor of $v$. The computational problem described informally above is now the following. <span style="font-variant:small-caps;">Strong Triadic Closure (STC)</span>\ **Input**: An undirected graph $G=(V, E)$ and an integer $k \in \mathbb{N}$.\ **Question**: Is there an STC-labeling $L=(S_L,W_L)$ with $|W_L| \leq k$? We call an STC-labeling $L$ *optimal* for a graph $G$, if the number $|W_L|$ of weak edges is minimal. The STC-labeling property can also be stated in terms of induced subgraphs: For every induced $P_3$, the path on three vertices, of $G$ at most one edge is labeled strong. Therefore, as observed previously [@KNP17L], <span style="font-variant:small-caps;">STC</span> is closely related to the problem of destroying induced $P_3$s by edge deletions. Since the graphs without an induced $P_3$ are exactly the disjoint union of cliques, this problem is usually formulated as follows. <span style="font-variant:small-caps;">Cluster Deletion (CD)</span>\ **Input**: An undirected graph $G=(V, E)$ and an integer $k \in \mathbb{N}$.\ **Question**: Can we transform $G$ into a *cluster graph*, that is, a disjoint union of cliques, by at most $k$ edge deletions? More precisely, any set $D$ of at most $k$ edge deletions that transform $G$ into a cluster graph, directly implies an STC-labeling $(E\setminus D,D)$ with at most $k$ weak edges. There are, however, graphs $G$ where the minimum number of weak edges in an STC-labeling is strictly smaller than the number of edge deletions that are needed in order to transform $G$ into a cluster graph [@KNP17L]. Due to the close relation between the two problems, there are graph classes where any minimum-cardinality solution for <span style="font-variant:small-caps;">Cluster Deletion</span> directly implies an optimal STC-labeling [@KNP17L]. In this work, we study the parameterized complexity of <span style="font-variant:small-caps;">STC</span> and <span style="font-variant:small-caps;">Cluster Deletion</span> and the classical computational complexity of both problems in graph classes that can be described by one forbidden induced subgraph of order at most four. #### Known Results. <span style="font-variant:small-caps;">STC</span> is NP-hard [@sintosL], even when restricted to graphs with maximum degree four [@KNP17L] or to split graphs [@konstantinidis_et_alL]. In contrast, <span style="font-variant:small-caps;">STC</span> is solvable in polynomial time when the input graph is bipartite [@sintosL], subcubic [@KNP17L], a proper interval graph [@konstantinidis_et_alL], or a cograph, that is, a graph with no induced $P_4$ [@KNP17L]. <span style="font-variant:small-caps;">STC</span> can be solved in ${\mathcal{O}}(1.28^k + nm)$ time and admits a polynomial kernel when parameterized by $k$. These two results follow from a parameter-preserving reduction to <span style="font-variant:small-caps;">Vertex Cover</span>, which asks if it is possible to delete at most $k$ vertices of a given graph such that the remaining graph does not contain any edge. This parameter-preserving reduction [@sintosL] computes the so-called Gallai graph [@Sun91; @Bang96] of the input graph and directly gives the above-mentioned running time bound. The existence of a kernel for parameter $k$ is implied by two facts: First, <span style="font-variant:small-caps;">Vertex Cover</span> admits a polynomial kernel for the number $k$ of vertices to delete [@Cyg+15; @DF13]. Second, <span style="font-variant:small-caps;">Vertex Cover</span> is in NP and <span style="font-variant:small-caps;">STC</span> is NP-hard. Hence, the <span style="font-variant:small-caps;">Vertex Cover</span> instance of size $\operatorname{poly}(k)$ which we obtain by first reducing from STC to <span style="font-variant:small-caps;">Vertex Cover</span> and then applying the kernelization can be transformed into an equivalent <span style="font-variant:small-caps;">STC</span> instance by a polynomial-time reduction. The STC instance then has size $\operatorname{poly}(k)$. <span style="font-variant:small-caps;">Cluster Deletion</span> is NP-hard [@SST04], even when restricted to graphs with maximum degree four [@KU12] or to $(2K_2,3K_1)$-free graphs [@GHN13], and solvable in polynomial time on cographs [@GHN13] and in time $O(1.42^k+m)$ on general graphs

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aliens' had been concentrated in the Buffalo Stadium, a sports stadium in the south of Paris, and the'suspects' in the Roland Garros Stadium. On that morning, probably because of the shortage of transport, the _Préfecture_ had ordered the local police stations to direct _all_ arrested men to the Buffalo camp. But, as appeared on our arrival at that place, they had forgotten to inform the camp authorities at Buffalo of their changed dispositions. It was the usual French muddle. I was the first non-enemy alien to pass through the control bureau of the camp; when I put my passport on the desk and saw the official's surprised face, it all came to me in a flash. 'When and where were you arrested?' asked the official. 'In the Café Dupont, Place de la Convention, an hour ago.' I did not consciously have to reflect for a second for my anwers. The brandy did it for me—or that sly, hairy super-ape, the subconscious. The point is that normally I am a bad actor, and if I try to bluff at poker I am always caught. It was a very odd experience. 'Where is your _carte_ __ _d'identité_?' 'At home—10, rue Dombasle, seventh floor. That is why I have been arrested. I just went down to have coffee after lunch and left my _carte_ __ _d_'_identité_ __ in the flat; there was a round-up and they took me to the police station. I asked them to let me go home and fetch the _carte_ __ _d'identité_, __ but they wouldn't listen—they just shoved me into the car and here I am.' I __ _felt_ that I was absolutely convincing—the right mixture of polite indignation and honest-to-God stupidity. And all the time I watched my own performance and wondered. Normally I am the rather uninspired type of person; when writing, for instance, I have to sweat out every line with a conscious effort. It was indeed very odd. In the same dream-like exaltation in another age, a person would perhaps have heard voices and produced a mystic vision; now miracles had to happen at police officials' desks; but it was fundamentally the same process. The man behind the desk turned my passport over and looked at my other papers: Press card, the famous letters from Influential Persons, etc. Over his head, there was a clock on the wall, and it marked 4.30. 'All this is a quite amusing experience for a journalist, but the bother is that I have an appointment at five o'clock,' I said—that is, the brandy said, or the hairy ape. 'What sort of appointment?' 'Why—the daily Press Conference at the Ministry of Information.' (I had never been at the Press Conference and I had not written an article since the war—but I had kept the Press card.) 'That idiot Lamèche is always making a mess of things,' said the man behind the desk to his assistant; he fumbled irresolutely with my papers. Lamèche, I gathered, was the _commissaire_ _de_ _police_ of the XVth Arrondissement. Our escort had left immediately after delivering us. 'Look,' I said. 'I have got to be there at five. If you still have doubts, send a man to accompany me home in a taxi while I fetch my _carte_ __ _d'identit_ _é_ _._ __ You can give me an armed escort and even a machine-gun if you think it necessary.' Opposite the desk was the door that led into the camp—and once through that door there was no returning. I had it before my eyes and I knew it was a death-trap; and I knew that the slightest shadow of a false ring in my Voice would finish me. But it was not my own voice, and I trusted it entirely. 'No, I don't think that's necessary,' said the man behind the desk and handed my papers back with a smile. 'You are free, monsieur. Sentry, take monsieur to the entrance gate.' And to his secretary: 'Remind me to ring that idiot Lamèche when we are through with the others.' And to me:'_Au_ __ _revoir_, __ _monsieur._ Next time you had better carry your _carte_ __ _d'identité_ on you.' On the way to the gate I picked up my suitcase which I had left outside the entrance to the office. The sentry did not notice that there was anything wrong about that. At the gate I gave him five francs and asked him to get me a taxi. The taxi arrived. Exit Hyde, enter Jekyll. But only for a few minutes, while the taxi approached the Porte d'Orléans and the drumming in my chest calmed down. Then the blessings of the brandy began to evaporate and I began to realise the situation in which I was. The camp official would ring Lamèche, or whatever his name was; in half an hour or so the game would be up and the police at my flat—this time perhaps really with a tommy-gun. I knocked at the window pane and gave the driver another address. I knew that I would never see my flat again. Exit Jekyll, enter Hyde. But this time for good. ## V I had either to give myself up to the police or to go to ground, taking the risk of having to face a military tribunal if caught. I decided on the latter course. I still had some friends. Who these friends were, how they passed me on in turn, hiding me for one night each, and how they finally succeeded in obtaining for me a travelling permit to Limoges, where a fortnight later I ceased legally to exist, will be an amusing and moving story to tell at a time when the night has gone from Europe and acts of kindliness and solidarity no longer count as crimes. But still it is night; and from the moment when at the Porte d'Orléans I gave the taxi driver a certain address, the story has to move along a dotted line, until G. and I emerge from an overcrowded train at the railway station at the town of Limoges, famous for its manufacture of porcelain and its retired generals. Those first days of June in Limoges were like a short coming up for air before the final dive. The Battle of Dunkirk was still in progress, giving France a last respite. I felt safe from the police for at least a fortnight. The travelling permit which my friends had procured me was a most respectable-looking document, covered with all sorts of lovely rubber stamps in black and red—my heart jumped with pleasure whenever I looked at it. It enabled me to go to the local police and provisionally legalise my situation; my _carte_ __ _d_'_identité_, with the revealing 'E,' was officially lost. In due time, of course, the _Préfecture_ of Limoges would report my arrival to the _Préfecture_ of Paris and would receive instructions to arrest me; but, what with red tape and the administrative chaos, this could hardly be expected to happen for another fortnight or three weeks. So there was time to take a deep breath and think matters over—like a man who, crashing down a precipice and catching hold half-way of a clump of grass, sighs with relief until the roots give way under his weight, and he continues his plunge to the bottom. Limoges was on one of the main roads along which the stream of refugees flowed down from north to south. My memories of those last days of France are mainly of an acoustic nature: the never-ceasing polyphonic symphony of motor horns, the roaring and humming of the engines, the thundering of the heavy lorries on the roadway, the asthmatic rattle of old Citroëns, the neighing of horses and the crying of exhausted children, as the chaotic stream flooded through the town on its aimless course. Without interruption, all day and all night, the mechanised divisions of disaster passed by and the people in the streets stared at them; some pityingly, some with hostile contempt, some with anxiously thoughtful eyes, wondering when their turn would come to join the Great Migration to the South. For they had watched the growing of the stream from the first days, when it was no more than a rivulet with its sources far away in the north, in Holland and Belgium, and the cars still bore foreign markings; then in the days of Sedan it had suddenly swollen and on the number plates appeared the signs of the French provinces, M for the Département du Nord, N for the Pas de Calais; and nearer and nearer, X for the Somme, Y for Seine-et-Oise, until the first green buses from Paris appeared and for a few days nine out of ten number plates bore the fatal R of the capital; then even the R's thinned out and new sources of the stream opened up in Brittany and on the Loire. The number-plates on the cars told the dreadful tale of the steam-roller thundering down over France, and revealed the truth which the official communiqués still tried to hide. G. and I used to sit on the terrace of the Café

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morning to some golf course in Virginia, and that he would wear the gas mask in the lake and retrieve the balls, and we'd split the money three ways._ _"Kerlin said, 'How do I stay down on the bottom?' I said, 'Oh, I've got that all worked out. What we will do is, you'll strip, and you'll be nude, but you'll wear my Washington Post newspaper bag, and we'll put barbell plates in the newspaper bag so that you'll stay on the bottom.'_ _"So we went out to this golf course, and all the way Kerlin was expressing some doubt. And Danly and I said, 'Have we ever failed? I mean, you're looking at a couple of guys...if you want to quit now, okay, but, you know, you're not in any future deals.'_ _"So we got out there at the crack of dawn. Kerlin was stripped, and we were dressed warmly. He was totally nude with a Washington Post newspaper bag on and all these barbell plates, and he started wading into the lake. Of course, he didn't know if he was stepping on snakes or golf balls or whatever. And then he got down and when he tugged on the rope, we pulled him back up. He said, 'I can't see anything.' We said, 'Don't worry about seeing anything, just grope around.' And he started to go back down._ _"But before his head went under, this truck came over the rise, carrying the guy that's going to fill up sand traps in the morning. He saw us and drove up, saying, 'What are you kids doing?' Danly and I were thinking fast. 'We're conducting an experiment for our high school physics class, sir.' Kerlin was nodding the whole time. So we had to get him out of the pond. The whole thing blew up on us."_ 21 Whatever happened to poor Kerlin, and however nude he actually was, a watered-down version of this story got around. It would be the last great Tom Sawyering of Warren's high school career. By now, however, he had made a small fortune: a glistening $5,000 heap, sticky with the newsprint from throwing more than five hundred thousand newspapers. Newsprint snowflakes made up more than half his snowball. Rich as he was, however, Warren meant to keep that snowball rolling.*8 **13** **The Rules of the Racetrack** _Omaha and Washington, D.C. • 1940s_ **W** arren's Dale Carnegie tests of behavior were handicapping: a mathematical experiment on human nature. The data he collected gave him the odds that Carnegie was right. This way of thinking was an extension of his childhood hobby of calculating the odds on the life expectancies of hymn composers. But his interest in longevity was no mere abstraction. Ernest Buffett, to whom Warren was extremely attached, had died in September 1946 at age sixty-nine, while the family was in Omaha campaigning for Howard's third term. Warren was sixteen. Of his four grandparents, only Stella, age seventy-three, remained alive, confined in the Norfolk State Hospital. Long before Ernest's death, Warren had been preoccupied with his own lifespan; these latest family events did nothing to ease his mind about either longevity or insanity. Warren's passion for handicapping, however, extended to many other subjects, and in an embryonic form had started much earlier—well before he even knew the meaning of the term—back when he was a little kid with marbles and license plates and bottle caps and a fingerprint kit for nuns. The art of handicapping is based on information. The key was having _more information than the other guy_ —then analyzing it right and using it rationally. Warren had first put this into practical use as a child down at the Ak-Sar-Ben racetrack, when his friend Bob Russell's mother introduced the boys to the world of pari-mutuel betting. Warren and Russ were too young to wager, but they quickly figured out how to make a buck. Amid the cigarette butts, beer slops, old programs, and hot-dog remnants in the grime and sawdust of the Ak-Sar-Ben floorboards were thousands of discarded tickets, peeping out like mushrooms on the forest floor. The boys turned themselves into truffle hounds. _"They call that'stooping.' At the start of the racing season you get all these people who'd never seen a race except in the movies. And they'd think that if your horse came in second or third, you didn't get paid, because all the emphasis is on the winner, so they'd throw away place and show tickets. The other time you would hit it big was when there was a disputed race. That little light would go on that said 'contested' or 'protest.' By that time, some people had thrown away their tickets. Meanwhile, we were just gobbling them up. We wouldn't even look at them when we were working. At night we'd go through them. It was awful; people would spit on the floor. But we had great fun. If I found any winning tickets, my aunt Alice, who didn't care anything at all about races, would cash them in for us, because they wouldn't cash them for kids."_ Warren wanted to go to the races all the time. When Mrs. Russell wasn't taking him, _"my dad would never go to the races,"_ says Buffett. _"He did not believe in the races."_ Instead, his parents let his great-uncle Frank, the oddball of the family, take him. Frank had long ago reconciled with Ernest and had eventually married a woman whom the family referred to as "the gold-digger."1 He had no particular interest in the horses, but he took Warren to Ak-Sar-Ben because his great-nephew wanted to go. At Ak-Sar-Ben, Warren had learned something about how to read the tip sheet, and it opened up a whole new world. Handicapping horses combined two things he was very, very good at: collecting information and math. It was not unlike counting cards at blackjack, except that the winning hand had four legs and ran around a track. Soon, he and Russ knew enough to put out their own tip sheet, the cannily named _Stable-Boy Selections_. _"We got away with it for a while. They weren't the hottest sellers in the world. I mean, a couple of little kids selling this thing we typed up in my basement on an old Royal typewriter. The limiting factor was carbons in those days. You could probably only get in five or so carbons. But I got on the Royal and Bob Russell and I doped out the horses and then we typed up this thing._ _"We were in the track, yelling, 'Get your Stable-Boy Selections!' But the Blue Sheet was the number-one tip sheet, and the racetrack was getting a commission on it. The Blue Sheet sold for a little more. At twenty-five cents, we were a cut-rate product. They shut down the Stable-Boy Selections fast because they were getting a cut on everything sold in the place except for us."_ When the Buffetts moved to Washington, D.C., the only plus for Warren was the chance to upgrade his handicapping skills. _"The one thing I knew about Congress was that Congressmen had access to the Library of Congress—and the Library of Congress had everything that had ever been written. So when we got to Washington, I said, 'Pop, there's just one thing I want. I want you to ask the Library of Congress for every book they have on horse handicapping.' And my dad said, 'Well, don't you think they're going to think it's a little strange if the first thing a new Congressman asks for is all the books on horse handicapping?' I said, 'Pop, who was out there at the county fairs stumping for your election? Who was down there at the packinghouses ready to get to the cops if something happened?' I said, 'And you're coming up for reelection in two more years. You're going to need me. So this is payoff time.' And he got me hundreds of books on horse handicapping._ 2 _"Then what I would do is read all these books. I sent away to a place in Chicago on North Clark Street where you could get old racing forms, months of them, for very little. They were old, so who wanted them? I would go through them, using my handicapping techniques to handicap one day and see the next day how it worked out. I ran tests of my handicapping ability day after day, all these different systems I had in my mind._ _"There are two kinds of handicappers. There are speed handicappers and class handicappers. Speed handicappers figure out the horse with the best times in the past. The fastest horse will win. Class handicappers feel that the horse that's run against ten-thousand-dollar horses and done well and now is running against the five-thousand-dollar horses will beat them. Because, they say, the horse runs just fast enough to win._ _"In horse racing it pays to understand both types of handicapping. But back then I was basically a speed guy. I was a quantitative guy to start with."_ As he tested, thought, and observed, Warren discovered the Rules of the Racetrack: **1.**

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UIUserInterfaceIdiomPhone) { return (interfaceOrientation!= UIInterfaceOrientationPortraitUpsideDown); } else { return YES; } } - (IBAction)cancelButton:(id)sender{ } - (IBAction)flashOn:(id)sender{ Class captureDeviceClass = NSClassFromString(@"AVCaptureDevice"); if (captureDeviceClass!= nil) { if ([device hasTorch] && [device hasFlash]){ [device lockForConfiguration:nil]; if (flashIsOn) { [device setTorchMode:AVCaptureTorchModeOn]; [device setFlashMode:AVCaptureFlashModeOn]; oneOff.text=@"On"; [_flashButton setImage:[UIImage imageNamed:@"flash-on-button"]]; _flashButton.accessibilityLabel = @"Disable Camera Flash"; flashIsOn = NO; //define as a variable/property if you need to know status } else { [_flashButton setImage:[UIImage imageNamed:@"flash-off-button"]]; _flashButton.accessibilityLabel = @"Enable Camera Flash"; oneOff.text=@"Off"; [device setTorchMode:AVCaptureTorchModeOff]; [device setFlashMode:AVCaptureFlashModeOff]; flashIsOn = YES; } [device unlockForConfiguration]; } } } - (void)dealloc { [[self session] stopRunning]; [super dealloc]; } - (void)storeFlashSettingWithBool:(BOOL)flashSetting { [[NSUserDefaults standardUserDefaults] setBool:flashSetting forKey:kCameraFlashDefaultsKey]; [[NSUserDefaults standardUserDefaults] synchronize]; } @end A: Please check your device settings. Goto privacy ---> Camera ---> check setting for your app-----> turn it on Run the app. It works. Cheers A: Change your dealloc Method [self.captureSession removeInput:self.videoInput]; [self.captureSession removeOutput:self.videoOutput]; self.captureSession = nil; self.videoOutput = nil; self.videoInput = nil; Q: Strange internet issues When I try and use any form of the internet, such as, apt-get, npm, the browser itself, etc, it hangs and cannot connect. However, when I ping, it can resolve hostnames and gets replies! I can SSH to it from inside the local network too. I've been having this issue and I can't find the solution anywhere! I'm using the RPi B+ Model 1 if that helps A: The only time I have read about anybody having those kinds of errors the solution seems always to be to start with a fresh new copy of Raspian. But there is a better solution: To protect against wierdnesses like this I use Win32DiskImager to save.img files periodically when the system is running correctly. That way I can always restore my system back to a known good condition. I name the image files with the date, i.e. 2016-09-29.img This way it restores any customization I have made so I do not need to start fresh and try to remember everything I have done with the system since the original install. g(y) = 6*y. Suppose 37*o - 5*o = 704. What is the lowest common multiple of o and g(2)? 132 Suppose -32 = -w - w. Suppose 0 = 2*c - 4*q - 12, c + 3*q = 2*q. Suppose 4 = -c*i, i + 24 = z - i. What is the smallest common multiple of w and z? 80 Let c(j) = -j**3 - j**2 - j + 1. Let o(r) = 5*r**3 + 4*r**2 + 10*r - 9. Let n(b) = -6*c(b) - o(b). What is the least common multiple of 8 and n(2)? 88 Calculate the least common multiple of -2 + 7/((-28)/(-24)) and 10. 20 Suppose -15 = -3*f, -5*v - 4*f + 0*f + 40 = 0. Let z(w) = -w + 0*w - 5 - v*w. Calculate the smallest common multiple of 18 and z(-5). 180 Let r = -40 - -60. What is the least common multiple of 6 and r? 60 Let t be (1/3)/((-1)/(-63)). Let s = 9 - 3. Find the common denominator of -65/3 and (s/t)/(4/(-22)). 21 Calculate the lowest common multiple of 6 and (-2408)/(-40) - (-1)/(-5). 60 Suppose 6 = l + 3. Let c(r) = r + 7. Calculate the lowest common multiple of ((-1)/(-2))/(l/54) and c(-6). 9 Let x = 32197/9 + -3570. Calculate the common denominator of x and 34/3. 9 Let a(l) = 6*l**3 - l**2 + 2*l - 9. Let q be a(6). Let u = q - 25343/20. Find the common denominator of u and 1 - ((-54)/(-40) - 0). 20 Let v = 229 + -173. Calculate the least common multiple of 14 and v. 56 Suppose -32 = -3*v - v. Suppose 9*j - 17 = -8. What is the lowest common multiple of j and v? 8 Find the common denominator of 19/10 and (-78)/(-60) - 1*-1. 10 Find the common denominator of 145/12 and (118/6)/(40/12). 60 Calculate the lowest common multiple of 3 and (2/(-8))/(5/(-40)). 6 Let o = -4049/20 - -1019/5. What is the common denominator of -113/20 and o? 20 Suppose 3*c - 6*a + a = 51, 0 = c + a - 25. What is the smallest common multiple of -16*3/(-12)*3 and c? 132 Suppose -5*h = 10, 2*m - 2*h - 44 - 4 = 0. Let l = 22 + -4. What is the least common multiple of m and l? 198 Suppose 0 = 4*d - 2*d - 32. Calculate the lowest common multiple of d and 4. 16 Let c = 44445081785/602 + -73828995. Let j = c + -3/301. What is the common denominator of 7/2 and j? 2 Suppose -3*n + 42 = 3*s, -2*s - 4*n + 7*n + 8 = 0. What is the smallest common multiple of s and 10? 10 Let s be (-30892)/(-8784) + 2/9. Let g = s + 2/183. Find the common denominator of g and 43/18. 36 Let m = -1065/28 + 114/7. Let x(n) = -753*n - 1. Let i be x(2). Let l = i + 7492/5. Calculate the common denominator of m and l. 20 Find the common denominator of -5/2 and -1 + 105/12 + 2. 4 Let v(r) = r**2 + 9*r - 12. Let p be v(-10). Let w = 5 + p. Calculate the lowest common multiple of -1*2*22/(-4) and w. 33 Let c(r) be the third derivative of r**5/60 + 7*r**4/24 + 4*r**2. What is the least common multiple of c(-8) and 8? 8 Let j = -5330/3 - -1798. What is the common denominator of -5/8 and j? 24 Let v be (-4 + (-2)/2)*-1. Let y(g) = -g**3 - 12*g**2 - 2*g - 6. Let m be y(-5). Calculate the common denominator of -131/6 and m/(-66)*v/(-3). 66 Let x be 7044*((-1)/1)/1. Let t = x + 549389/78. Let n = -3/26 + t. Find the common denominator of n and 17/11. 33 What is the common denominator of 0/1 - (-35)/63 and -19/3? 9 Suppose -4*k = -5*k. Suppose k = -3*a + 16 - 1, -a + 13 = 4*y. What is the lowest common multiple of 6/(-4)*120/(-9) and y? 20 What is the common denominator of 125/6 and (2 - (-148)/(-112)) + 3?

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metrics attributes. Metrics attributes are measurements used in software tests to locate potential problem areas within the software application. Different than a “bug,” metrics attributes are desired standards in the design and operation of the software application, rather than mistakes or errors in the functionality of the software application. Testing “good code” is not purely a consideration of error-free code; instead “good code” is considered for complexity, extensibility, modularity, readability, etc. Testing tools are often used to determine values of metrics attributes. Formulas may be used to calculate numerical values for particular metrics attributes. Metrics may be oriented towards a particular design or programming paradigm. For example, object-oriented metrics attributes are metrics designed specifically to evaluate the performance of object-oriented code. Examples of objected-oriented metrics attributes include Depth of Inheritance Tree (DIT), Number of Children (NOC), Coupling Between Objects (CBO), Weighted Methods per Class (WMC), Response for Class (RFC), Nesting Tree (NT), Message Passing Coupling (MPC), etc. Each metrics attribute, object-oriented or otherwise, provides different information as to quality of the object-oriented code; the information may relate to functions, classes, or an entire software system. For example, MPC is a measure of message passing among classes, indicating a measure of coupling between a class and an entire software system. Determining a value of MPC provides an indication of software application complexity. Although a measured value of a metrics attribute may be out-of-bounds (either high or low), the software application may not necessarily be flawed. Metrics attributes give guidance as to desired standards, but are not necessarily mandates. Many techniques may be used to determine values of metrics attributes. One such technique is static analysis. Static analysis is a process of examining source code or compiled code without executing the source code or compiled code. Static analysis is typically used to locate problem areas in the source code or compiled code, e.g., potential bugs, unnecessary complexity, or high maintenance areas. Several mechanisms (similar to compilers) are used to perform static analysis, e.g., lexical or binary scanning, parsing, semantic analysis, data flow analysis, etc. For example, after testing an object-oriented software application, a value of the MPC metrics attribute of Class X may be found to be high, indicating Class X is strongly coupled. Strongly coupled classes are closely tied together, so that modifications attempted to one class are more likely to affect the other class, should modification be required. In a typical scenario, the MPC metrics attribute, along with other metrics attributes, are compiled into performance reports and discussed with the management team. The management team suggests improvements to problem areas in the source code, e.g., to improve the message coupling of Class X. The improvements are communicated to the development team for resolution. There is a definite cost associated with time, money, resources (tools and people), and space expended to develop a software system using this process.Q: Repository pattern in MVC: controller code explanation What is the purpose of SudentRepository in this example? Why do I need one? public class StudentController : Controller { private IStudentRepository _repository; public StudentController() : this(new StudentRepository()) { } public StudentController(IStudentRepository repository) { _repository = repository; } A: I updated to actually include a specific question that I think you're getting at. The purpose of StudentRepository is to encapsulate interactions with persisted data. The Controller need not know if its stored in a db, flat file, in memory, etc. The reason you're injecting it in via an interface is because you may eventually have multiple implementations of that repository, and the interface is just a contract to ensure basic functionality across all implementations. This is called constructor injection (a type of dependency injection) in case you want to learn more. y) = 6*y**3 + 2*y**2 + y. What is t(z)? -5 Let c(v) = -v**3 - v**2 + 2*v + 2. Let o be c(0). Let w(y) = 4*y**3 + 2*y - 5*y**3 - 2 - y**2 + 2*y**3 + y. Give w(o). 8 Suppose -3*t = 3, 0*j + 2*j = -2*t - 14. Let l(d) be the third derivative of -d**4/24 - d**3/6 + d**2. Calculate l(j). 5 Let g(x) be the first derivative of -x + 1/2*x**2 - 1 + 1/6*x**3. Let i(v) be the first derivative of g(v). What is i(-3)? -2 Let j be (-85)/15 - (-4)/6. Let d(z) be the first derivative of z**3/3 + 3*z**2/2 - 3*z + 2. What is d(j)? 7 Let a = 9 + -4. Let i = -7 - -14. Let v(b) = 3*b + i - b**2 - b + 0. Calculate v(a). -8 Suppose -3*w - 30 = -3*t, -w - 40 = -4*t - 2*w. Suppose -25 = 5*c, -3*c = -k - 4*k + t. Let f(g) = g. Give f(k). -1 Suppose -g = 2*g - 5*v - 127, -4*v - 86 = -2*g. Let h be g/9 + 5/(-15). Let d(r) = r**3 - 3*r**2 - 2*r - 1. Calculate d(h). 7 Let u(q) = 8*q. Suppose x - 5 = j, 4*x = 5*j + 4 + 20. What is u(x)? 8 Let n(c) = -c**3 - 6*c**2 + 8*c + 6. Let k(a) = -a**2 + 8*a - 7. Let z be k(8). What is n(z)? -1 Let y(m) = -m**3 + 5*m**2 - 3*m. Let k(n) = -3*n**3 + 16*n**2 - 10*n. Let d(q) = 2*k(q) - 7*y(q). What is d(2)? -2 Let v(p) = 3*p + 4. Let w be (-2 + 0)/(4/10). Let g(r) = -3*r + 10. Let o(f) = -f + 1. Let y(c) = g(c) - 6*o(c). Let k(b) = w*v(b) + 4*y(b). Determine k(-4). 8 Let u(o) = 8*o**2. Suppose 5*w = w - 4. Give u(w). 8 Suppose -3 - 7 = -4*c + 2*f, c - 25 = 5*f. Let b(z) be the first derivative of c - z**2 + 1 + 0. What is b(1)? -2 Let d(j) be the first derivative of j**4/4 + 4*j**3/3 - j**2/2 + 4*j - 18. Calculate d(-4). 8 Let x(v) = -v**3 - 3 - 703*v**2 + 698*v**2 + 6*v - 2*v. Give x(-6). 9 Let q = -41 - -44. Let x(k) = 2*k**2. What is x(q)? 18 Let a = -2 - -12. Suppose -3*u + g + a = 0, u + 3*g - 6 = -2*u. Let y(h) = -h + u + 0*h + 0. Give y(2). 1 Suppose -2*n - 2 + 0 = 0. Let w(o) = -o**2 + 4*o + 7. Let t be w(5). Let j(y) = -2*y + 4 - t - 1. Calculate j(n). 3 Let l(z) = -z - 6 - 7 + 10. Calculate l(-2). -1 Suppose 0 = 4*r - 3*b - 17, -2*b = r - 4*b - 8. Suppose -3*w + 5 = a - 6, w - 13 = r*a. Let s(k) = k**2 - 7*k + 1. Calculate s(w). -9 Suppose -3*c + 1 = -2*n, -n + 3*c + 10 = 3. Let f be 1*(n + 6 + -3). Let i(k) = -k + 7. What is i(f)? 12 Let n(k) = -5*k**2 - 2*k + 1. Let i(b) = -b**2 + 6*b - 4. Let s be i(7). Let p(w

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I suppose the same thing is true in France as in America. Neither here nor there can you find equality of results. All you have a right to expect is equality of opportunity. II. The great symbol and instrument of this idea of equal opportunity in the United States is the common school. In every State of the Union provision is made for the education of the children at public expense. The extent and quality of this education, the methods of control, the standards of equipment, even the matter of compulsory or voluntary attendance, vary in different States and communities. But, as a rule, you may say that it puts within the reach of every boy and girl free instruction from the _a_-_b_-_c_ up to the final grade of a _lycee_. The money expended by the States on these common schools in 1905-1906 was $307,765,000,--more than one-third of the annual expenditure of the national government for all purposes, more than twice as much as the State governments spent for all other purposes. This sum, you understand, was raised by direct, local taxation. Neither the import duties nor the internal revenue contributed anything to it. It came directly from the citizen's pocket, at the rate of $3.66 a year _per capita_, or nearly $13 a year for every grown-up man. How many children were benefited by it? Who can tell? 16,600,000 boys and girls were enrolled in the public schools (that is to say, more than 70 per cent of the whole number of children between five and eighteen years of age, and about 20 per cent of the total population). The teachers employed were 109,000 men, 356,000 women. The average daily expenditure for each pupil was 17 cents; the average annual expenditure, about $25. In addition to this number there are at least 1,500,000 children in privately endowed and supported schools, secular or religious. The Catholic Church has a system of parochial schools which is said to provide for about a million children. Many of the larger Protestant Churches support high schools and academies of excellent quality. Some of the most famous secondary schools, like Phillips Exeter and Andover, St. Paul's, the Hill School, Lawrenceville School, are private foundations well endowed. These figures do not mean much to the imagination. Statistics are like grapes in their skins. You have to put a pressure upon them to extract any wine. Observe, then, that if you walked through an American town between eight and nine in the morning, and passed a thousand people indoors and out, more than two hundred of them would be children going to school. Perhaps twenty of these children would turn in at private schools, or church schools. But nine-tenths of the little crowd would be on their way to the public schools. The great majority of the children would be under fourteen years of age; for only about one child out of every twenty goes beyond that point in schooling. Among the younger children the boys would outnumber the girls a little. But in the small group of high-school children there would be three girls to two boys, because the boys have to go to work earlier to earn a living. Suppose you followed one of these groups of children into the school, what would you find? That would depend entirely upon local circumstances. You might find a splendid building with modern fittings; you might find an old-fashioned building, overcrowded and ill-fitted. Each State, as I have said before, has its own common-school system. And not only so, but within the State there are smaller units of organization--the county, the township, the school district. Each of these may have its own school board, conservative or progressive, generous or stingy, and the quality and equipment of the schools will vary accordingly. They represent pretty accurately the general enlightenment and moral tone of the community. Wealth has something to do with it, of course. People cannot spend money unless they have it. The public treasury is not a Fortunatus' purse which fills itself. In the remote country districts, the little red schoolhouse, with its single room, its wooden benches, its iron stove, its unpainted flagstaff, stands on some hill-top without a tree to shadow it, in brave, unblushing poverty. In the richer cities there are common school palaces with an aspect of splendour which is almost disconcerting. Yet it is not altogether a question of wealth. It is also a question of public spirit. Baltimore is nearly as large and half as rich as Boston, yet Boston spends about three times as much on her schools. Richmond has about the same amount of taxable property as Rochester, N.Y., yet Richmond spends only one-quarter as much on her schools. Houston, Texas; Wilmington, Delaware; Harrisburg, Pennsylvania; Trenton, New Jersey; New Bedford, Massachusetts; and Des Moines, Iowa, are six cities with a population of from 80,000 to 100,000 each, and not far apart in wealth. But their public-school bills in 1906 varied as follows: Des Moines, $492,000; New Bedford, $472,000; Harrisburg, $304,000; Trenton, $300,000; Wilmington, $226,000; and Houston, the richest of the six, $163,000. If you should judge from this that the public schools are most liberally supported in the North Atlantic, North Central, and Far Western States, you would be right. The amount that is contributed to the common schools per adult male inhabitant is largest in the following States in order: Utah, $22; North Dakota, $21; New York, $20; Colorado, $20; Massachusetts, $19; South Dakota, $19; Nebraska, $17; and Pennsylvania, $16. The comparative weakness of the common schools in the South Atlantic and South Central States has led to the giving of large sums of money by private benevolence, the Peabody Fund, the Slater Fund, the Southern Education Fund, which are administered by boards of trustees for the promotion of education in these backward regions. The Spirit of America strongly desires to spread, to improve, to equalize and coordinate, the public schools of the whole country. Is it succeeding? What lines is it following? Where are the changes most apparent? First of all, there is a marked advance in the physical equipment of the common school. In the villages and in the rural districts the new buildings are larger and more commodious than the old ones. In many parts of the country the method of concentration is employed. Instead of half a dozen poor little schoolhouses scattered over the hills, one good house is built in a central location, and the children are gathered from the farmhouses by school omnibuses or by the electric trolley-cars. Massachusetts made a law in 1894 requiring every township which did not have a high school to pay the transportation expenses of all qualified pupils who wished to attend the high schools of neighbouring towns. In many States text-books are provided at the public cost. In the cities the increased attention to the physical side of things is even more noticeable. No expense is spared to make the new buildings attractive and convenient. Libraries and laboratories, gymnasiums and toilet-rooms, are provided. In some cities a free lunch is given to the pupils. The school furniture is of the latest and most approved pattern. The old idea of the adjustable child who could be fitted to any kind of a seat or desk, has given way to the new idea of the adjustable seat and desk which can be fitted to any kind of a child. School doctors are employed to make a physical examination of the children. In a few cities there are school nurses to attend to the pupils who are slightly ailing. Physical culture, in the form of calisthenics, military drill, gymnastics, is introduced. Athletic organizations, foot-ball clubs, base-ball clubs, are encouraged among the boys. In every way the effort is apparent to make school life attractive, more comfortable, more healthful. Some critics say that the effort is excessive, that it spoils and softens the children, that it has distracted their attention from the serious business of hard study. I do not know. It is difficult for a man to remember just how serious he was when he was a boy. Perhaps the modern common-school pupil is less Spartan and resolute than his father used to be. Perhaps not. Pictures on the wall and flowers in the window, gymnastics and music, may not really distract the attention more than uncomfortable seats and bad ventilation. Another marked tendency in the American common school, at least in the large towns and cities, is the warm, one might almost say feverish, interest in new courses and methods of study. In the primary schools this shows itself chiefly in the introduction of new ways of learning to spell and to cipher. The alphabet and the multiplication table are no longer regarded as necessities

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37470, 2929, 432, 2057, 3786, 11462, 2929, 390, 5795, 37470, 2929, 3580, 15, 187, 187, 12236, 1984, 5593, 27, 374, 15, 22, 3, 57, 20, 15, 22, 3, 380, 32880, 40011, 3120, 2953, 5098, 476, 320, 2326, 187, 187, 11837, 3239, 310, 2624, 581, 387, 247, 673, 1955, 281, 253, 2060, 414, 273, 253, 2953, 4910, 285, 256, 3006, 327, 253, 3120, 15, 380, 1232, 3936, 690, 4465, 673, 13, 533, 310, 973, 4409, 352, 7296, 352, 310, 760, 436, 2408, 273, 673, 642, 4465, 22852, 29095, 390, 2341, 403, 12845, 275, 253, 2403, 273, 436, 2199, 984, 352, 310, 1160, 432, 6313, 1966, 1612, 15844, 309, 9012, 281, 4266, 670, 841, 32622, 342, 619, 1966, 1612, 43387, 309, 717, 278, 962, 272, 689, 1051, 1281, 434, 923, 604, 352, 24094, 15, 8247, 281, 253, 9400, 14, 7243, 512, 253, 7223, 403, 15978, 2624, 597, 403, 39214, 285, 22377, 3033, 512, 2366, 275, 1355, 39657, 15, 187, 187, 3039, 368, 897, 247, 9140, 3120, 513, 368, 871, 752, 6569, 281, 634, 1711, 9140, 8364, 32, 1310, 253, 4657, 2506, 626, 761, 21724, 731, 368, 476, 1900, 5321, 731, 323, 441, 24457, 1310, 323, 5913, 1921, 10430, 441, 634, 8364, 285, 26246, 310, 562, 273, 253, 1953, 428, 309, 6888, 436, 13103, 747, 4660, 387, 378, 461, 22900, 253, 643, 1388, 15, 309, 2427, 2819, 323, 436, 2714, 2715, 273, 308, 1406 ]

: 100.0%; height: 100.0%" ></div> <div class="region matched" style="left: 0.0%; top: 0.0%; width: 100.0%; height: 100.0%" ></div> </div> <h5>Mask:</h5> <img src="mask.png" /> <h5>Greyscale, masked:</h5> <img src="grey.png"> <ul> <li>Maximum pixel intensity: 255 <li>threshold=10 </ul> <h5>Non-black pixels in region:</h5> <img src="non_black.png" /> </div> </body> </html>Preoperative computed tomography imaging in the management of impacted mandibular third molars. The purpose of this study was to examine the role of preoperative computed tomography (CT) imaging of the inferior alveolar nerve (IAN) for patients at increased risk for nerve injury during mandibular third molar (M3) extraction. To address the research purpose, the investigators enrolled a sample composed of subjects who presented for mandibular M3 extraction and had panoramic radiographic signs interpreted as being associated with an increased risk for inferior alveolar nerve injury. All subjects had preoperative CT imaging studies done to ascertain the position of the IAN with respect to M3. The predictor variable was the preoperative assessment of risk for IAN injury based on panoramic imaging. The outcome variable was the preoperative assessment of IAN injury risk after reviewing the CT studies. We documented the number of IAN injuries. Descriptive statistics were computed as indicated. The sample consisted of 23 patients who had bilaterally impacted wisdom teeth. The sample's mean age was 26 +/- 6 years (range: 18-48 years); 69.6% of the patients were female. After reviewing the panoramic radiographic, 80.4% of M3s were classified as having an increased risk for IAN injury. Upon examining the CT imaging, 32.6% were classified as high risk for IAN injury. After reviewing all imaging studies, 71.7% of the teeth in the sample were extracted. Intraoperative IAN visualization occurred in 21.2% of the cases. At 1 week postoperative, 3 patients had dysesthesia (9.1%); none had a permanent nerve injury. In this small series of patients, the additional information provided by 3-dimensional imaging changed the majority of patients from increased risk for nerve injury to low risk for nerve injury.Quilt patterns and Sunbonnet Sue are our passion here at Prairie Cottage Corner. Click the link to the right, to view and purchase our products. Join us and see our many free items and instructions on how to quilt, applique' and embroider. Got your cup of tea and a scone? Let's visit. Please "FOLLOW" us and leave a comment or two. We love to hear from you. We're going to have a lot of fun stitching and visiting. Translate Friday, October 18, 2013 New Quilt Patterns for Christmas and Winter "Dashing" is one of our newest quilt wall hanging patterns for winter and Christmas. It's fun to decorate these little projects. With this one, I found some lovely brass bells for the harness of the horse. They really jingle. These models were machine quilted by Lise Ott at Experience Quilts! quilt shop in Odessa, WA. This is a pattern for the less-experienced quilter wanting to learn applique' techniques and a little piecing. The directions in all these new patterns are complete for one wanting to learn. These are good patterns for classes in quilting. The projects are small, usually under a yard in dimension, and the shapes are quite simple. The patterns even include the embroidery stitches needed to do the embellishments. These patterns include instructions for fusible web applique' and freezer paper applique'. The corner of the blanket is blowing out behind as the pony trots swiftly on, weighted with a little bead and some stem stitching. Below, is the center block for "Midnight Feast", a small wall hanging done in violet batiks, for the most part. Winter is a hard time for some of our little forest friends. On this frigid night, some bunnies receive a present from Mr. Snowman! He's all decked out for the season. Here's some of the detail work, below, and a complete picture of the center block with borders and snowballs (above). We used some sequin-like leaves for Mr. Snowman's decorations. "Twas the Night" is the name of our third winter decorative quilt. The pattern includes the words to Clement Moore's poem as well as a recipe for old-fashioned Sugar Plums (seen dancing over the child's head). Mom reads to her daughter, warm and cozy. Here's the whole piece. The blocks for these quilts are simple and the patterns include all the directions needed to assemble them. We hope you enjoyed this preview. You can purchase these Leaf Wreath Wall Decoration Pattern Google+ Badge Holidays to Love FREE Fons and Porter Log Cabin Ebook! Download Your Free Log Cabin Quilting Pattern eBook from Fons & Porter's Love of Quilting Now! Many quilters love free log cabin quilting patterns because of their honored history. This free eBook from Fons & Porter's Love of Quilting features three different type of free log cabin quilting blocks: chevron log cabin quilt blocks, courthouse steps quilt blocks and traditional log cabin quilt blocks. This free eBook also outlines how simple a log cabin quilting pattern can be from the first step of selecting a block style down to choosing a setting for your blocks. Whatever type of log cabin quilt block you choose, this free eBook from Fons & Porter will show you how simple learning how to make a log cabin quilting pattern can be! QuiltWoman Craftsy Followers - I follow those who follow me....that way, we can visit..... December Banner ON SALE NOW! $3 - Sue's getting all ready for the Christmas Holiday! Google+ Followers Sign up to receive new posts as soon as they're written..... Please refrain from copying.... Please refrain from copying pictures or text from our blog without written permission, except recipes. Pictures and text are the exclusive property of Prairie Cottage Corner unless explicitly offered as a free gift to all. Thank you for your attention to this important caution.Hot Topics: THIS WEEK’S HIGH SCHOOL FOOTBALL SCHEDULE San Dimas High School and head coach Bill Zernickow, looking to win a second consecutive CIF-Southern Section title, begins its season by hosting Monrovia on Friday. The 2014 prep football season begins Thursday. (Keith Birmingham Pasadena Star-News)--- title: 'Using external libraries' --- Coming soon... Pages Tuesday, April 19, 2011 Product Spotlight: Address Books Have you ever just stepped over the magazine subscription cards at the store? Take a second and think of how many of these cards are discarded as "trash" to everyone at the store... Or all the ones that clutter your home and recycling bin since every magazine seems to need at least 8 of them... We have put these cards to good use in a mini address books. :) Now every time we go to the grocery store I get super excited to "clean-up" the magazines some. In fact, the silver lining to my ridiculously long appointment last week was that I got a ton of magazine subscription cards once I ransacked all of the magazines and organized everything in boredom. It is a really fun instant gratification item to collect!!! These pocket size address books pack plenty of space to keep all your addresses in this ever expanding digital world where some still like snail mail. Each address book is made inside either a discarded metro/transit card or gift card. Inside the card and a thicker back cover there is a range of (20)magazine subscription cards from a variety of magazines. In the back there are some "blank" pages for notes that are made with recycled paper from either previously printed paper or alternative recycled paper products. Address book measures: 2.5"X3.5" The NYC metro card address books can be seen Each page is cut one at a time due to the individuality of the address fields and sizing on the card. The process takes some extra time, but is well worth it considering it is only this amount of time no extra fossil fuels or energy are utilized in the making of this project because it is made from pure human power!!! I laugh to myself about these shirts with my human power slogan I am mulling over... Let's see if it sticks. Back to the topic- Once all the pages are individually cut they are punched and spiral bound all together in small batches. When you use a gift card do you know what happens to your old gift cards? If the store doesn't recycle them you can always save them for us ;) If for whatever reason sending us your cards and junk is out of the question - I discovered this awesome new station at Bust Buy the other day. I went looking for this special version of Tron

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travel information. One of the few places in Jinghong with an English-speaking staff, Meimei Café serves Western and Chinese favorites, as well as great coffee and juices. **Known for:** burgers; coffee; nice atmosphere. _Average main: Y45_ _2 Menglong Lu, Jinghong_ _0691/216–1221_ _No credit cards_. **Mekong Café** (湄公咖啡馆 _Méigōng kāfēiguǎn_ ) $ | **FRENCH** | Opened by a Frenchman who was once a hotel chef and his Chinese wife, Mekong Café is a favorite with all sorts of travelers. Backpackers, expats, couples as well as locals gather on its large front and back patios to enjoy afternoon dessert, delicious French cuisine, Chinese classics, or simply a drink to recover from the Jinghong heat. **Known for:** view; pizza; offers travel advice. _Average main: Y30_ _F1–104 Kingland International, Menglong Lu, Jinghong_ _0691/216–2395_ _www.mekongcafe.cn_. h **Hotels** **Anantara Xishuangbanna Resort & Spa** (西双版纳安纳塔拉度假酒店 _Xīshuāngbǎnnà ānnàtǎlā dùjìa jiǔdiàn_ ) $$$$ | **RESORT** | **FAMILY** | On the banks of the Luosuo River, this luxury resort is in Menglun, about 60 km (37 miles) from Jinghong. **Pros:** perfect service; great views; sparkling pool. **Cons:** expensive; service is inconsistent; remote. _Rooms from: Y2000_ _Country Road 009, Menglun_ _691/893–6666_ _xishuangbanna.anantara.com_ _80 rooms, 23 villas_ _Breakfast_. **Dai andYi Ethnic Minorities** s **Dai** Related to Thais and speakers of languages belonging to the Tai-Kadai family, the Dai seem much more Southeast Asian than Chinese. In China they are primarily located in the Xishuangbanna, Dehong, and Jingpo regions of southern Yunnan, but can also be found in Myanmar, Laos, and Thailand. They practice Theravada Buddhism, the dominant form of Buddhism in Southeast Asia. The linguistic, cultural, and religious connections with Southeast Asia give Dai-inhabited regions a decidedly un-Chinese feel. Within China, they are most famous for their spicy and flavorful food and their Water Splashing Festival (water is used to wash away demons and sins of the past and bless the future). Many grow rice and produce such crops as pineapples, so villages are concentrated near the Mekong (Lancang) and Red (Honghe) rivers. The Dai population here has ebbed and flowed with China's political tide, and many are now returning after the turmoil of the 1960s and '70s. **Yi** Descendants of the Qiang people of northwestern China, the Yi (aka Sani) are scattered across southwestern China in Yunnan, Sichuan, and Guizhou provinces as well as Guangxi Zhuang Autonomous Region. The largest concentration of the more than 6½ million Qiang descendants are in Sichuan's Liangshan region. They live in isolated, mountainous regions and are known for being fierce warriors. Notable traits include their syllabic writing system, ancient literature, and traditional medicine—all of which are still being used today. The Yi also sport extravagant costumes that vary according to geographical region. Massive black mortarboard-style hats, blue turbans, ornate red headdresses, and other headwear complement brilliantly colored vests and pants. Their language is part of the Tibeto-Burman language family and similar to Burmese. Some Yi also live in Vietnam, where they are called the Lolo. **Crown Hotel** (皇冠大酒店 _Huángguàn dà jiǔdiàn_ ) $ | **HOTEL** | In the heart of Jinghong, the Crown Hotel has several low-slung buildings in a parklike setting with a lily-leaf-shape swimming pool. **Pros:** central location; night market nearby; good value. **Cons:** tired rooms; too few English-speaking staff; noisy. _Rooms from: Y350_ _70 Mengle Dadao, Jinghong_ _0691/219–9888_ _121 rooms_ _No meals_. **Yourantai** (悠然台 _Yōurán tái_ ) $$ | **RESORT** | The "Terrace of Serenity" more than lives up to its name. **Pros:** excellent atmosphere; gorgeous setting; amazing mattresses. **Cons:** minimum stay required; steps to climb; remote. _Rooms from: Y1280_ _2 Galan North Rd., Jinghong_ _138/8793–4096_ _www.yourantai.com_ _No credit cards_ _6 rooms_ _Breakfast_. b **Shopping** On Zhuanghong Lu in the northern part of town, there's a handicrafts market filled with Burmese jade jewelry and goods from Vietnam and Thailand. Assume that much of it is counterfeit. There is a small but vibrant night market on Mengla Lu outside the Crown Hotel. Genuine Pu'er tea can be safely bought from the tea shop in the Golden Zone hotel. # Side Trips from Jinghong s **Sights** **Ganlan Basin** (橄榄坝 _Gǎnlǎn bà_ ) **FOREST** | One of the more scenic areas of Xishuangbanna is this valley 37 km (23 miles) from Jinghong. Locals still live in bamboo huts in the beautiful rain forest. The area is famous in Yunnan for its tropical flowers and its millions of butterflies. _Jinghong_. **Sanchahe Nature Reserve** **NATURE PRESERVE** | One of China's first serious attempts at ecotourism, the 900-acre Sanchahe Nature Reserve is home to wild elephants. Two hours north of Jinghong, the park also features a butterfly farm and a cable car that offers breathtaking views. Lodging is in "tree houses" about 25 feet above ground—a unique place to spend a night. _Jinghong_. **Xishuangbanna Tropical Botanical Garden** (西双版纳热带植物园 _Xishuāngbǎnnà rèdài zhíwùyuán_ ) **FOREST** | The nearest large town in the area, Menglun, is the location of China's largest botanical garden. With a gorgeous setting on a peninsula in the Luosuo River, the garden holds more than 13,000 tropical and subtropical plant species and a section of dense, unspoiled tropical rain forest. A museum tells about the local flora and fauna, as well as the humans that have inhabited the region. Families enjoy the humid and fragrant air of the tropics, picnicking in pavilions, and observing rare plants and animals. Visits can take anywhere from a few hours to an entire day (there are restaurants and places to stay overnight). Electric buses help you explore, and hop-on, hop-off tickets are available for Y100. TIP → **Buses only run until 6 pm, so start at the eastern park and make your way back toward the entrance.** Menglun is about 60 km (37 miles) east of Jinghong, a trip that takes about 90 minutes by bus. Or you can take a cab. _Menglun_ _Y100_. **Yiwu** (易武 _Yì wǔ_ ) **TOWN** | Once one of the starting points of the ancient tea and horses trade route to Tibet, this village has an Old Town featuring the houses of the "tea lords" of yesteryear. The Old Town is hidden away behind the school on a hill and makes for very pleasant investigation for an hour or two. Yiwu's higher altitude also means that it's a great way to get away from the Jinghong heat. All around the area are tea plantations you can stroll in. Several buses to Yiwu leave from Jinghong daily. _Yiwu_. # WELCOME TO SICHUAN AND CHONGQING TOP REASONS TO GO Emeishan: Hike 10,000 feet to the top of one of China's holy mountains and a UNES

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see Integrating Local Additions, at time of writing for recent MiKTeX 2.9 (but the included images are from an older version, seemingly MiKTeX 2.5, and slightly different, cf. also http://docs.miktex.org/2.5/manual/localadditions.html ). The denomination there is “User-Managed TEXMF Directory” (see also additional note at the very end of this answer). Anyway, here an alternative description: Create a folder somewhere on your computer – with an important exception. It must not be a subfolder of your MiKTeX installation (it worked this way in older MiKTeX versions, but was changed for security reasons). Avoid as far as possible spaces in the path, it is a potential risk for malfunction. For use with MiKTeX portable the folder must be, of course, on the same drive as the MiKTeX installation, it will be saved as relative path. Here I will use c:\localtexmf. This folder must be TDS compliant (see thereto A Directory Structure for TeX Files); MiKTeX will complain, if not. What you need, depends on what you want to install into this directory, at least a tex\latex subtree should be sufficient. You will go safe, if you mimic the structure of the (itself TDS compliant) MiKTEX tree, but binaries can directly go into a subfolder c:\localtexmf\bin. Now, using the GUI: In the Start Menu go to the MiKTeX entry and open the settings – if you act as admin respectively “Settings (Admin)”, of course. The “MiKTeX Options” window will open. Go to the “Roots” tab. Click on “Add” and choose c:\localtexmf\. If there are more than one local directory, one can choose the search order with the “Up” and “Down” buttons. Now the almost most important part: Go to the “General” tab and click there on “Refresh FNDB” (FNDB = File Name Data Base). In some cases, especially if new fonts are installed, one has to press also the “Update Formats” button. If you’d forget this step, all earlier steps would be done to no purpose. Otherwise, using the command line (as admin always add the switch --admin): Execute initexmf --register-root=c:\localtexmf, followed by initexmf --update-fndb (shorter: initexmf -u). (In every step you can add the switch --verbose to get more information about, what happens.) Remark: For compatibility reasons there’s also the older switch --user-roots=<local-texmf-dir>, what according to initexmf --help registers user root directories, I assume also in administrative mode, but in http://docs.miktex.org/manual/initexmf.html it is not mentioned any more, so I must guess. In the case, a bin subfolder for binaries was created, it should be registered in the environment variable %PATH% before the binaries subtree of MiKTeX own installation, see e.g. How To Manage Environment Variables in Windows XP or a third-party tool like Env-Man or RapidEE. Then you need a system restart to take effect. An issue, that cannot be solved: A system wide environment variable, set by an admin, is always read before a user specific one. Then as a simple user you can only write and use batch files with an own %PATH% included. All user created local texmf trees can be disabled by temporary removing from the MiKTeX roots (cf. additional note at the end). See also How can I manually install a package on MiKTeX (Windows). For the sake of completeness, here’s a description, how to remove a local TeXMF tree from MiKTeX, with c:\localtexmf\ as example: GUI: Go again to the “Roots” tab in the settings (“MiKTeX Options” dialogue), select the directory c:\localtexmf\, and click on “Remove” on the lower side of the window. After that you must again refresh the FNDB and perhaps update the format files. Command line (also here: as admin add the switch --admin): Execute initexmf --unregister-root=c:\localtexmf, followed by initexmf --update-fndb. If you have uninstalled a font, additionally execute initexmf --mkmaps. The --verbose switch can be added, as well. If you do not need the bin subfolder anymore, the environment variable %PATH% must be cleaned up. Then the folder tree c:\localtexmf\ could safely be deleted. Additional Note A hint first: In Command Prompt you can type echo %Variable% with %Variable% e.g. %Userprofile%. So you can see to which value the variables expand on your system. Precisely the phrase “in MiKTeX there’s by default no local texmf tree installed” in the question is not true. MiKTeX adds itself several trees under %UserProfile% and in admin mode also to %AllUsersProfile% (in the following the MiKTeX denomination comes first): “UserConfig”: %AppData%\MiKTeX\<version>\ “UserData”: %LocalAppData%\MiKTeX\<version>\ (since Windows Vista) or %UserProfile%\<Local Settings>\<Application Data>\MiKTeX\<version>\ (until Windows XP, the strings <Local Settings> and <Application Data> are language dependent) only in admin mode used “CommonConfig” and “CommonData”: %AllUsersProfile%\MiKTeX\<version>\ (since Windows Vista) or %AllUsersProfile%\<Application Data>\MiKTeX\<version>\ (until Windows XP, the string <Application Data> is language dependent) The actual paths you can see with the GUI in the “MiKTeX Options” window under the “Roots” tab or with the command line interface by executing initexmf --report. Disadvantages of all these local trees: They can only be changed on installation, cf. Changing the location of auto-installed packages in MiKTeX, and they cannot be disabled (by temporary removing from the MiKTeX roots). For additional information see Difference between administrative and user mode of MiKTeX. A capacitor is a passive two-terminal electrical device used to store energy within an electric field, and contains at least two electrodes separated by a dielectric region. The capacitance of a capacitor is proportional to the surface area of the electrodes, and inversely proportional to the thickness of the dielectric region. Some examples of capacitors include deep trench (DT) capacitors and metal-insulator-metal (MIM) capacitors. DT capacitors are formed directly within a substrate, whereas MIM capacitors are formed within a back end of line (BEOL) metallization stack.class Base def foo() :base end end class Derived < Base def foo() :derived end end class Interpreter attr_accessor :ret def do_a() @ret += "there, "; end def do_d() @ret += "Hello "; end def do_e() @ret += "!\n"; end def do_v() @ret += "Dave"; end Dispatcher = { "a" => instance_method(:do_a), "d" => instance_method(:do_d), "e" => instance_method(:do_e), "v" => instance_method(:do_v) } def interpret(string) @ret = "" string.each_char {|b| Dispatcher[b].bind(self).call } end end assert 'demo' do interpreter = Interpreter.new interpreter.interpret('dave') assert_equal "Hello there, Dave!\n", interpreter.ret end assert 'Method#arity' do Class.new { attr_accessor :done def initialize; @done = false; end def m0() end def m1(a) end def m2(a, b) end def mo1(a = nil, &b) end def mo2(a, b = nil) end def mo3(*a) end def mo4(a, *b, &c) end def mo5(a, *b, c) end def mo6(a, *b, c, &d) end def mo7(a, b = nil, *c, d, &e) end def ma1((a), &b) nil && a end def run assert_equal(0, method(:m0).arity) assert_equal(1, method(:m1).arity) assert_equal(2, method(:m2).arity) assert_equal(-1, method(:mo1).arity) assert_equal(-2, method(:mo2).arity) assert_equal(-1, method(:mo3).arity) assert_equal(-2, method(:mo4).arity) assert_equal(-

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represent the same species (i.e. *H*. *c*. *labuanensis*) or two different species. **IUCN status:** Least Concern **Recorded at: Pahang**: Krau Wildlife Reserve \[[@pone.0179555.ref011], [@pone.0179555.ref041], [@pone.0179555.ref042]\], Tasik Chini \[[@pone.0179555.ref043]\], Kuala Atok, National Park \[[@pone.0179555.ref044]\], Bukit Ibam, Kemasul, Jengka, Klau Besar, Kenong and Gunung Aais \[[@pone.0179555.ref100]\]; **Terengganu**: Pasir Raja, Dungun \[[@pone.0179555.ref015]\], Tasik Kenyir \[[@pone.0179555.ref069]\]; **Negeri Sembilan**: Pasoh Forest Reserve \[[@pone.0179555.ref045]\], Gunung Angsi Forest Reserve \[[@pone.0179555.ref100], [@pone.0179555.ref101]\], Berembun Forest Reserve \[[@pone.0179555.ref101]\]; **Perlis:** Wang Kelian State Park \[[@pone.0179555.ref050]\]; **Selangor**: Ulu Gombak \[[@pone.0179555.ref054], [@pone.0179555.ref101]\], Air Hitam Forest Reserve \[[@pone.0179555.ref055]\], Semangkok Forest Reserve \[[@pone.0179555.ref101]\]; **Melaka**: Lata Bujang Forest Reserve \[[@pone.0179555.ref056]\], Unspecified \[[@pone.0179555.ref068]\]; **Johor**: Endau- Kluang Forest Reserve and Endau-Kota Tinggi Forest Reserve \[[@pone.0179555.ref056]\], Gunung Panti and Labis Forest Reserve \[[@pone.0179555.ref100]\]; **Kedah:** Ulu Muda Forest Reserve \[[@pone.0179555.ref057]\], Bukit Hijau \[[@pone.0179555.ref100]\]; **Kelantan**: Air Panas-Gua Musang, \[[@pone.0179555.ref061]\]; **Perak**: Temenggor Lake \[[@pone.0179555.ref069]\], Kledang Saiong Forest Reserve, \[[@pone.0179555.ref100]\]; **Pulau Pinang**: Bukit Panchor \[[@pone.0179555.ref100]\]. *H*. *cervinus* forages in forest understory and roosts in limestone caves and crevices amongst boulders in very large colonies of up to 100,000 individuals \[[@pone.0179555.ref011], [@pone.0179555.ref014]\]. ***Hipposideros cineraceus*** Blyth, 1853 *Hipposideros cineraceus* Blyth, 1853: 410; near Pind Dadan Khan, Salt Range, Punjab, PAKISTAN (W. Theobold, Esq., collector; Type unknown) \[[@pone.0179555.ref126]\]. **Common English name:** Ashy Roundleaf Bat **Barcode Index Number:** A DNA barcode (BM460-04) recorded as *H*. cf. *cineraceus* was collected in Pahang, Peninsular Malaysia and associated with the BIN, BOLD:AAI8259 ([Fig 4](#pone.0179555.g004){ref-type="fig"}). **Remarks:** Murray et al. \[[@pone.0179555.ref125]\] reported two forms of *H*. *cineraceus* sensu lato from Peninsular Malaysia. A specimen from Perak, Peninsular Malaysia had a large forearm (42.9 mm), echolocated at 152 kHz and showed a high divergence (9.2--15.1%) in ND2 mtDNA from other specimens; while a smaller specimen from Pahang, Peninsular Malaysia (forearm = 39.3 mm) echolocated at 144 kHz and showed 10.4--12.2% divergence in ND2 mtDNA. This is congruent with Khan et al. \[[@pone.0179555.ref032]\] who discovered an average divergence of 8.7% in cytochrome *b* mtDNA among specimens of *H*. *cineraceus* sensu lato from Krau Wildlife Reserve. Four BINs are associated with DNA barcodes named as *H*. *cineraceus* on BOLD ([Fig 4](#pone.0179555.g004){ref-type="fig"}). Our NJ analysis ([Fig 4](#pone.0179555.g004){ref-type="fig"}) did not cluster the DNA barcodes from Peninsular Malaysia and Borneo (BOLD:AAI8259) with other DNA barcodes of *H*. *cineraceus* from Vietnam, Laos and Borneo but clustered the barcodes more closely to *H*. *atrox* (BOLD:ACE5015 and BOLD:ACE6229) from Peninsular Malaysia instead. According to Kingston et al. \[[@pone.0179555.ref011]\], *H*. *cineraceus* resembles *H*. *bicolor/atrox* closely but is distinct with a smaller body size and a slightly raised bump at the internarial septum. In addition, the average echolocation frequency for *H*. *cineraceus* is 144 kHz and for *H*. *atrox* is 142 kHz. Further analyses including more specimens from across the region are required to examine the status of the bats recorded as *H*. *cineraceus* in Peninsular Malaysia. Consequently, we tentatively retained the name in this checklist. **IUCN status:** Least Concern **Recorded at: Pahang**: Krau Wildlife Reserve \[[@pone.0179555.ref011]\], Fraser Hill Forest Reserve \[[@pone.0179555.ref056]\], Jengka \[[@pone.0179555.ref100]\]; **Kedah**: Pulau Langkawi \[[@pone.0179555.ref023]\], Ulu Muda Forest Reserve \[[@pone.0179555.ref057]\]; **Selangor**: Ampang \[[@pone.0179555.ref023]\], Bukit Kutu Wildlife Reserve \[[@pone.0179555.ref051]\], Ulu Gombak \[[@pone.0179555.ref052]\]; **Johor**: Pulau Pisang \[[@pone.0179555.ref023]\], Labis Forest Reserve \[[@pone.0179555.ref100]\]; **Perak**: Temengor Forest Reserve \[[@pone.0179555.ref046]--[@pone.0179555.ref048]\], Royal Belum State Park \[[@pone.0179555.ref048]\]; **Kelantan**: Gunung Reng and Gua Musang \[[@pone.0179555.ref062]\], Gunung Stong State Park \[[@pone.0179555.ref100]\]; **Melaka:** Unspecified \[[@pone.0179555.ref068]\]; **Terengganu**: Bukit Dendong \[[@pone.0179555.ref097]\]. *H*. *cineraceus* roosts in caves or similar structures such as culverts, often with other *Hipposideros* species \[[@pone.0179555.ref011], [@pone.0179555.ref014], [@pone.0179555.ref023]\]. ***Hipposideros diadema*** \[Geoffroy, 1813\] *Rhinolophus diadema* Geoffroy, 1813: 263, pls. 5, 6; Timor Island, INDONESIA (Péron and Lesueur, collector; MNHN 918) \[[@pone.0179555.ref127]\]. *Hipposideros diadema* \[[@pone.0179555.ref008]\]. **Common English name:** Diadem Roundleaf Bat **Barcode Index Number:** BOLD:AAB8310 (7 DNA barcodes from Peninsular Malaysia; [Fig 4](#pone.0179555.g004){ref-type="fig"}) **Remarks:** Murray et al. \[[@pone.0179555.ref125]\] compared specimens of *H*. *diadema* from Peninsular Malaysia and *H*. *pelingensis* from Kabaena Island, Southeast Sulawesi, and reported that the species have similar body size and were 2.7% divergent in ND2 mtDNA, although they did not observe *H*. *diadema*'s distinctive white spots on *H*. *pelingensis*. In contrast, they reported that specimens of *H*. *diadema* from Peninsular Malaysia and the smaller *H*. *diadema* from Sulawesi are 8.5% divergent in ND2 mtDNA. DNA barcodes recorded as *H*. *diadema* are associated with three BINs, BOLD:AAB8308, BOLD:AAB8309, and BOLD:AAB8310. Congruent with Murray et al. \[[@pone.0179555.ref125]\], the three BINs appear to correspond to geographical regions ([Fig 4](#pone.0179555.g004){ref-type="fig"}). Four subspecies are recognised under *H*. *diadema

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ote, or something with a more leisurely pace, this island delivers an abundance of hiking options suitable for all abilities. From coastal strolls to steep ascents, you can take things at your own pace while enjoying the natural beauty and wildlife along the journey. 4. A wealth of watersports With over 200 kilometres of beautiful coastline, it’s no surprise that watersports heavily feature in the list of things to do on the island. Besides the typical doughnut rides and banana boats you find on the main resort beaches, you’ll also find numerous water-based fun to be had during your time in Lanzarote. Whether you fancy roaming the shoreline above by boat or marvelling at the tropical marine life while scuba diving, Lanzarote is awash with reasons to hit the beach and dive right in. 5. Something for everyone One of the most important reasons to get active in Lanzarote is that regardless of your interests, you’re sure to find something that inspires you to get out and about. With villa holidays in Lanzarote, everyone can create lasting memories - whether that’s going underground in the Green Cave’s lava tunnels, snorkeling the coral reefs or hiking the volcanic landscapes and valleys. With adventure and natural beauty at every turn it caters for abilities and personal tastes. If you’re planning a vacation in Lanzarote and want to add a little adventure to your holiday, then we hope you’ll find plenty of reasons to get out there and get active. And with a stay in some of the best villas in Lanzarote, you’ll find the perfect home-from-home after a busy day discovering the delights on the island.This invention relates to portable lighting devices, specifically to a portable task lighting device which comprises a wheeled base having two elongated front legs that are each set into a singular unchanging position during use and two rotatable back legs that can be independently moved toward or away from one another prior to being set into a variety of fixed positions for use. The lighting device also has an upwardly telescoping mast centrally connected to the wheeled base which locks the front legs into their fixed usable positions, a pivot block connected to the top of the mast which comprises a plurality of positive locking positions, a boom arm connected to the pivot block, and an elongated fluorescent light assembly pivotally connected to the free end of the boom arm for a full 360.degree. of rotation. The combination of its telescoping mast which preferably extends between approximately thirty-two and ninety inches, its pivoting boom arm, and its rotatable light assembly allows the present invention to be placed into a nearly infinite number of configurations. It is contemplated during use for the elongated light assembly to always be positioned over the front legs for maximum stability, particularly when the telescoping mast is fully extended, and for the mast to have an asymmetrical or other cross-sectional configuration so that weight of the elongated light assembly and boom arm will not cause an unexpected rotation of any one of the extended telescoping members relative to the remainder of the telescoping mast structure. Thus the task lighting device of the present invention is stable, versatile, and adjustable into a nearly infinite number of usable positions to cast a broad, glare-free, and cool flood of light upon a targeted work surface. The present invention is also configured to be quickly and easily collapsed into a compact configuration for transport or storage by the removal of one quick-release pin from the pivot block and the loosening of several quick-release clamping devices that fix the telescoping mast members and rear legs in place during use. Applications may include, but are not limited to, indoor use for a wide variety of light-sensitive work projects that for proper completion require a direct source of shadow-free lighting.Clinicopathological study of gastric leiomyogenic tumors. 1. Seventy cases of the leiomyogenic tumors were found in 5451 resected stomachs; 49 leiomyoma, 17 leiomyosarcoma and 4 leiomyoblastoma. These leiomyogenic tumors occupied 40.5% of 173 submucosal tumors of the stomach. 2. The average age was 51.7 in leiomyoma, 57.3 in leiomyosarcoma and 41.6 in leiomyoblastoma with male predominance. 3. The leiomyoma and leimyosarcoma were frequently found in the upper 2/3 of the stomach. 4. The size of the tumors was within 3 cm in diameter in about 80% of leiomyoma with ulcer formation of 10.2% and over 3 cm in about 88% of leiomyosarcoma with ulcer formation of 64.7%. 5. The classification of the leiomyogenic tumors into the benign and malignant was occationally difficult. For the diagnosis of the leiomyosarcoma, the number of mitosis, irregularity of nucleus, increase of cellularity and decrease of smooth muscle production were helpful.Sometimes a blog must serve as a repository of regrets, a place to atone for not including some perfect fact in a book. While working on my book Parasite Rex, I came across many delicious examples of parasites manipulating the behavior of their hosts for their own benefit. After the book came out, I met scientists who enlightened me about other examples which would have been wonderful to include. A few years back, for example, a Johns Hopkins scientist pointed me to a parasitic wasp that turns cockroaches into zombies. I’ve recently been wondering about behavior-altering viruses, thanks to an online conversation I had with Ian Lipkin, a virus hunter at Columbia University, about my new book A Planet of Viruses. Lipkin wondered aloud if some viruses would turn out to manipulate their hosts for their own good. Did herpesviruses, for example, increase its transmission by boosting their host’s sexual desire? Most of the examples I knew about came from parasitic animals and fungi. The only virus that could have this kind of effect that I knew of was rabies, which causes its hosts to become more aggressive. A rabid dog that bites anything that crosses its path may be able to spread the virus more. But I suspected that there were many other puppet master viruses out there. Well, while I was at California State University Fresno last week to give a talk, I met an entomologist named Fred Schreiber. He asked me if I had ever heard of baculoviruses. They rang a bell in my head, but only faintly. So Schreiber told me an eldritch tale… Baculoviruses infect invertebrates, with each species of virus typically infecting only one species of host. Caterpillars are a particularly favorite target; the insects swallow baculoviruses sprinkled on the leaves they munch. (“How did the viruses get there?” you may ask. Very good question–which we’ll get to in good time.) Once inside the caterpillar, a baculovirus infects a host cell. The cell produces huge numbers of new baculoviruses. They come in two forms. Some of the viruses can slip out of the host cell on their own to infect new cells. Others stay in the cell, which makes huge quantities of a viral protein called polyhedrin. The viruses become embedded in massive polyhedrin blocks, like fruits in a fruitcake. A caterpillar may produce 10 million viruses from swallowing a single viral fruitcake. It even becomes visibly swollen with all its new viruses. Soon the virus-packed host gets an uncontrollable urge to creep its way to the tops of plants, where it clamps on tight, hanging down as shown in the picture above. In fact, scientists noticed these strange death throes long before they knew that baculoviruses that caused it. They dubbed it tree-top disease. After an infected caterpillar takes its position at the top of a plant, the virus releases an enzyme that literally makes the animal dissolve. The tough viral fruitcakes come tumbling out, landing on leaves below where they can infect a new host. Hearing about tree-top disease gave me a deep sense of deja vu. A number of very different parasites have evolved the same strategy for getting to new hosts. Just a couple weeks ago, for example, I blogged about a fungus that sends its ant hosts to the undersides of leaves, whereupon the fungus sprouts branches out of the ant’s head and showers spores down on new victims. Lancet flukes send their hosts up to the tips of grass blades so that they can be eaten by grazing cows and sheep. It’s fascinating that even a virus–with just a few genes–can trigger this behavior as well. Scientists have identified one of the genes in baculoviruses that is crucial for this manipulation. It causes insect hosts to start wandering in response to light. Strangely, the virus appears to have acquired this gene through a kind of evolutionary theft. The viral gene bears a striking resemblance to a gene in insects. In the insects, the gene is involved inforaging for food. It’s possible that an ancestral baculovirus picked up the host gene, which then evolved to take on a different behavior–one that sent insects to their doom, rather than to a meal. All in all, this zombie strategy is terrifically successful for baculoviruses. They are everywhere, killing insects in staggering numbers. In 1973, scientists bought heads of cabbage around Washington DC and discovered that they were coated in baculoviruses. A single serving of cabbage contained up to 100 million of them. Fortunately, baculoviruses are so finely adapted to invertebrate hosts that they pose no threat to humans. In fact, we can use baculoviruses to our advantage. Scientists can remove the polyhedrin gene from the viruses and replace it

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ball it would have died, and I’m equally sure I would have felt horrible as they both dropped out of the sky, but they never did. The bat would always realize, often times at the last second, that the missile was way too big to be even the most succulent moth and swoop away. It was a long time before I realized that this game must have been positively infuriating from the bat’s point of view. As incredible as this aerial display was, I didn’t really fall in love with bats until I moved to New Hampshire. I spent a summer living in the attic of a cabin in Fraconia Notch State Park, and early, early in the morning I would hear incessant squeaking coming from a corner of the ceiling. I assumed it was one of the mice I was in a constant state of battle with that summer. One evening as I was getting ready to go to bed, from the same corner I saw a bat drop out of the crack where the ceiling met the log wall. I stood frozen in the middle of that room and I could hear the fluttering sound of its wings as it flew around the room for nearly half a minute. Even in the confines of that tiny room it was an agile flyer, swooping around me, the furniture, and the walls without crashing into any of them. While I was startled by this first appearance I didn’t really mind it. Maybe I truly did miss the last train to crazy-town, but a bat seemed like short change to the plastic-chewing, food-seeking, hantavirus-carrying, no-kill-trap eluding rodents that I was currently at war with. Besides, if I couldn’t even rig a trap for a mouse, successfully evicting a bat was way out of my league. That’s when I started doing more research. Quite a few of the people I told about the bat immediately raised the concern of bats carrying rabies. As it turns out, according to the CDC, less than six percent of bats that are captured and tested carry rabies. That figure doesn’t even take into account all of the bats that are happily zipping around like tiny furry fighter pilots. There is a high percentage of human rabies cases that are caused from bats, but in many cases the patient did not seek medical attention for a trivial little bat bite. What’s more, in the majority of these cases the person was bitten while trying to remove the bat. I made a mental note to go to the doctor if I got bitten, or saw evidence that the bat was diseased and stopped worrying about it. I also was surprised to hear people say that bats made a habit of flying into people’s hair. My own observations of their ability to navigate contradicted the idea and many sources dismissed it. I hardly pay any attention to my hair anyways, and a bat stylist might have been an improvement. But I did learn something that worried me. Biologists were concerned by something called “White Nose Syndrome.” It had started with bats in New York State, and it was disrupting the bats during their winter hibernation causing them to be spotted flying around and eating snow. It was killing enormous numbers of bats, and other than a few vague references to a fungus, no one seemed to understand what was causing the bats to die. And no one knew what to do about it. I won’t say we always got along perfectly during my summer of the bats. For one thing, their habit of squeaking noisily in the ceiling at five in the morning got old fast. I also remember waking up one night to realize that a bat was noisily rustling around on top of a plastic bag that had one of my knitting projects in it. (I vaguely remember muttering “You can share my room, but stay out of my yarn!”) But more often than not I was delighted when they (literally) dropped in. I vividly remember watching one crawl around upside down using the hook-like thumb on it’s wing. I was surprised, having been told that bats need to drop from a perch to be able to fly, to see a bat crawl around on the floor in the corner of the room and then effortlessly flutter back up into flight. Besides, having a bat for a roommate earned me at least a few bragging rights. My summer in New Hampshire eventually ended. I moved back to civilization away. While I didn’t start liking bats any less, I certainly didn’t think about them as much. I still heard snippets about White Nose Syndrome here and there, and it still worried me, but I was too busy with my non-bat life to really stay in the loop. About a week ago a bomb was dropped on me. I got an email saying that Icebox Cave in Cuyahoga Valley National Park was being closed due to concerns over White Nose Syndrome. A confirmed case of White Nose Syndrome was found nearby in one of the Summit County Metroparks. I hadn’t even noticed that another case of White Nose Syndrome was confirmed in Ohio nearly a year ago. Even worse a case of White Nose Syndrome was confirmed not far from my cabin in New Hampshire the same year that I was there. The year afterwards bat populations all over the state plummeted. Even though I’m thousands of miles away in California now it’s struck a nerve. Those are my bats, in my favorite places, the ones that I used to play “dive at the softball,” with and yelled at to keep out of my stuff. I want to do something about it this time around. Although we have learned more about it, we still haven’t figured out how to stop White Nose Syndrome from killing bats. It’s caused by a cold loving fungus that probably originated in Europe. When the bats hibernate for the winter, particularly in caves and mine shafts, the fungus grows around their nose, causes lesions on their skin, and disrupts their hibernation causing them to waste precious energy stores flying around when there isn’t a food source available. White Nose Syndrome has devastated the affected bats, killing anywhere from 70 to 100 percent of their original populations. Many efforts to protect bats have been focused on preventing people from spreading the fungus. Countless parks and preserves have closed caves and mines to prevent the spores from being introduced to places where bats are known to hibernate. The Fish and Wildlife Service is encouraging cavers to decontaminate their gear before entering caves. Another way to help bats is by protecting their healthy populations. Avoid disturbing them when they are hibernating and protect the forests and wetland areas where they live and hunt. Hang bat houses to provide a place for them to live. Avoid using pesticides that kill the insects that they depend on for food. Finally, even if you can’t welcome a bat into your house, at least welcome them into your heart. As insect eaters and pollinators they play an important part in agriculture and our own food chain, not to mention mosquito control at your next barbecue. They are truly fascinating critters that are often unnoticed or feared for all the wrong reasons. They could use a little more love. You can find more information about bats and White Nose Syndrome from these wonderful places: categories Other Places You Can Find Us contact us about the content All posts are property of the author. Photos are property of the post author unless otherwise noted. Contact us with any requests for use of our content. We accept guest posts and would be happy to do the same for your blog. Just let us know!Super excited for these discs so I had to use my cruddy webcam to share them. Soft Proton Ion and a slightly used Lat 64 Bite. The Soft Proton plastic feels amazing and I have been looking for the Bite for a while now. Pup seems to like it and I got to throw these around a bit today. I'm almost sad to say I'm retiring my FLX Challenger from round play although now I'll finally have a putter pair of the same mold.▲ Brian Kibler will not be casting the Hearthstone Grandmasters finals at BlizzCon. It was only a matter of time until an influencer within the Hearthstone community would issue a public statement regarding Activision Blizzard's recent decision to ban Ng "blitzchung" Wai Chung for using his post-game interview to make a political statement calling for the liberation of Hong Kong amid political unrest out east. The first domino fell Wednesday morning when long-time caster, popular streamer, and community figure, Brian Kibler, shared a statement on his official website. Not one to shy away from speaking his mind or voicing his stances on politics, Kibler did not hold back his feelings as this one hits particularly close to home for him. Within the 788-word post, Kibler acknowledged the bravery it took for blitzchung to use his platform to issue a statement that would almost certainly put his career and personal safety in jeopardy. That being said, he understands and agrees with Blizzard handing down a punishment for his actions. "Even so, I do think that Blizzard was correct in issuing him a penalty for his actions. They do not want to set the precedent for their official broadcasts being used as political tools. The players agreed to particular rules for behavior, and he violated those rules. I have seen many descriptions of the situation claim that Blizzard took action against Blitzchung “for his support of the Hong Kong protests”, but that’s

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and extraordinary) beams cannot interfere, since the optical path difference is longer than the coherency of the light. Since the ratio of lengths is 2:1, partial beams with the same polarization plane are spaced by a common distance longer than the coherent length. Such partial beams do not interfere because of the distance longer than the coherent length, although they have the same polarization plane. A cross-term in the square of the amplitude vanishes. Thus, the square of the amplitude becomes constant for all partial beams with different polarization planes. All partial beams with different polarization planes have the same energy. This is a depolarized state. The long optical path difference eliminates interference of the beams with the same polarization planes. A single depolarizer only requires such simple conditions (BL>C, ratio=2:1). However, some difficulties will occur when two depolarizers are included in optical paths of a fiber-optic gyroscope. Will no interference between two beams which have once an optical path difference longer than the coherent length by passing through a depolarizer occur forever? Can the function for separating the optical paths of a depolarizer ensure everlasting non-interference between the once separated beams? The two beams can interfere with each other. When two beams pass through the other depolarizer, the birefringence of the second depolarizer will affect against the once-obtained separation between two beams. Sometimes the birefringence will decreases or cancel the path difference which has been endowed by the first depolarizer. In some cases, the optical path difference will become shorter than the coherent length of the light. Then, two beams will interfere! Rotation of polarization planes often occurs in a single-mode fiber, because phase constants of the beams degenerate in a single-mode fiber. If the rotation of the polarization planes occurred, the intensity of the interference beams would fluctuate, because the two once-separated beams with the same polarization planes would interfere. The fluctuation of the interference beams appears as a noise, a drift or change of the scale factors of the signals. Such a problem would appear in an gyroscope for the first time, when the Inventors introduce two depolarizers into it. Thus, the Inventors have noticed the difficulties in a twin-depolarizer gyroscope for the first time. Nobody take notice of such a problem. A purpose of this invention is to solve the problem of a twin-depolarizer gyroscope.Q: How many distinct kanjis or words are there in a typical modern Japanese book? "typical modern book " means: It's a modern book and hardly uses ancient languages or any topolects. It's something like a famous novel(not a short story) or book with a high reputation. It's a normal book, not a dictionary or technique book. Additionally, I wonder how many distinct characters can cover 99.7% of the book content. The source of the problem is that I want to know how many unstudied (the meaning of) kanjis I will meet when reading a book. A: There are currently 2136 常用漢字. However, using writers will often use 漢字 outside of this list. So I ran a script to calculate the total number of unique 漢字 in Harry Potter and the Chamber of Secrets (a modern novel mentioned there) and on ノルウェイの森/Norwegian Wood (a "famous" Japanese language novel, though perhaps not "typical") and compared it to the 常用漢字 list. You can see some of the code (it just has the results for the distinct values in the books) here. Here's what I got Harry Potter and the Chamber of Secrets: 206 non-常用漢字 out of 1768 漢字 (肱 might be a typo for 肘, 躯 for 体, 荊 for 茨, and 綴 for 絞. I also wonder if 姐 and 嬉 are old forms or my source text has typos. I also have no clue about 杵 and 磔, which are likely wrong. I'll try to confirm with a physical copy in the future.) {'蘇', '捌', '曾', '鈎', '撫', '剥', '捷', '篭', '恰', '鍮', '撒', '涎', '虱', '樽', '炸', '塵', '椀', '吼', '淀', '絢', '歪', '掠', '瞥', '揉', '眩', '董', '錆', '嘘', '楊', '蝶', '靄', '疼', '呆', '叱', '弛', '攣', '棍', '猾', '藁', '軋', '荊', '揃', '纏', '甥', '這', '樫', '苺', '掻', '惚', '杖', '煤', '咳', '煽', '辻', '瓢', '詫', '捺', '脛', '溢', '溜', '蝋', '鎧', '糞', '芻', '腿', '噛', '唸', '痺', '鍔', '霞', '狡', '翠', '昂', '罠', '燭', '蜘', '牢', '躯', '叩', '杵', '雛', '佇', '鳩', '呟', '灼', '爛', '逢', '嘴', '黴', '呑', '兎', '嘩', '濡', '轟', '鞄', '咎', '棘', '笥', '壷', '閃', '猜', '楓', '聡', '麿', '箪', '捧', '馴', '藹', '蛙', '肱', '馳', '覗', '釘', '茜', '埃', '愕', '雀', '皺', '躇', '鋸', '踝', '穣', '奢', '檻', '箒', '姐', '甜', '嵌', '萄', '螺', '嬉', '唖', '秤', '仔', '掴', '窪', '狼', '翔', '綴', '腔', '箔', '芍', '躊', '鮭', '磔', '鱗', '悶', '禿', '躓', '蛛', '惹', '閂', '哮', '瓜', '腑', '曙', '槌', '沫', '狐', '倦', '卿', '剃', '栗', '燻', '頷', '憑', '斧', '蟻', '橙', '竿', '怯', '紐', '穢', '耽', '尖', '咆', '凱', '蒼', '肋', '錘', '踵', '窩', '縞', '竪', '痙', '鞭', '吊', '喧', '聳', '髭', '焚', '廻', '斐', '堵', '頬', '醇', '瘤', '鋏', '葡', '〇', '鉤', '鷲', '漉', '舐', '滲', '堰'} ノルウェイの森/Norwegian Wood: 167 non-常用漢字 out of 1746 漢字 (Like before 姐 and 嬉 might be old forms/typos. I'll try to confirm with a physical copy in the future) {'梯', '遙', '鱸', '鎧', '梢', '徨', '撞', '喧', '昂', '雀', '而', '鳩', '庇', '轟', '燈', '葡', '拗', '函', '禿', '悶', '槌', '訊', '紐', '碗', '鞄', '鮭', '蝕', '蛙', '軋', '舐', '檻', '湘', '茗', '萄', '蓮', '鯵', '綺', '裳

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17,500 我将会带着正式的命令回来进行全面调查 716 00:37:17,530 --> 00:37:18,200 我明白 717 00:37:18,400 --> 00:37:22,200 与此同时我建议您把注意力集中到人民自由联盟上 718 00:37:22,230 --> 00:37:24,200 我很清楚他们是你们的死对头 719 00:37:24,700 --> 00:37:26,100 我们将尽可能帮助你 720 00:37:26,300 --> 00:37:26,800 先生 721 00:37:27,600 --> 00:37:28,100 抱歉 722 00:37:30,600 --> 00:37:32,800 杰克的小组已经在建筑物外的集结地了 723 00:37:32,830 --> 00:37:33,600 我马上就到 724 00:37:33,900 --> 00:37:35,800 程先生抱歉 725 00:37:37,000 --> 00:37:37,900 我要回去工作了 726 00:37:38,400 --> 00:37:40,000 我的人会护送你出去 727 00:37:40,400 --> 00:37:40,900 谢谢 728 00:37:45,700 --> 00:37:46,500 埃德加 729 00:37:48,000 --> 00:37:48,600 抱歉 730 00:37:49,000 --> 00:37:51,500 埃德加斯蒂勒通信分析员是吧？ 731 00:37:51,600 --> 00:37:52,400 是的我很忙 732 00:37:52,700 --> 00:37:55,400 我忘记问布坎南先生最后一个问题了 733 00:37:55,430 --> 00:37:56,500 也许你能帮我 734 00:37:56,600 --> 00:37:57,350 我帮不了你 735 00:37:57,380 --> 00:37:58,290 你应该去问他 736 00:37:58,320 --> 00:37:59,200 不是什么机密问题 737 00:37:59,300 --> 00:38:03,800 奥德丽瑞恩斯提到说你早些时候帮助她整理国防部的文件 738 00:38:04,300 --> 00:38:05,900 是的在她被叫到医务室以前 739 00:38:06,000 --> 00:38:07,400 那么就剩你和杰克了？ 740 00:38:08,900 --> 00:38:09,600 什么？ 741 00:38:09,800 --> 00:38:10,700 埃德加过来 742 00:38:11,700 --> 00:38:12,400 我得走了 743 00:38:12,500 --> 00:38:12,800 再见 744 00:38:13,700 --> 00:38:14,000 谢谢 745 00:38:16,000 --> 00:38:16,600 你个白痴 746 00:38:16,630 --> 00:38:16,860 什么？ 747 00:38:16,900 --> 00:38:17,900 管好你的嘴 748 00:38:17,930 --> 00:38:18,900 我什么也没说 749 00:38:26,100 --> 00:38:26,500 你好 750 00:38:26,800 --> 00:38:29,000 袭击领事馆的主谋是杰克鲍尔 751 00:38:29,300 --> 00:38:30,500 调出所有他的档案 752 00:38:30,600 --> 00:38:31,300 回来我要看 753 00:38:31,400 --> 00:38:31,800 好的 754 00:38:36,100 --> 00:38:37,300 Michael 你到位了吗？ 755 00:38:37,500 --> 00:38:38,200 是的 756 00:38:38,900 --> 00:38:40,400 他在你两点钟的方位干掉他 757 00:38:40,430 --> 00:38:41,000 明白 758 00:38:54,200 --> 00:38:54,600 我们准备好了 759 00:38:55,800 --> 00:38:56,900 启动程序吧 760 00:39:13,200 --> 00:39:13,800 我们这边完成了 761 00:39:28,500 --> 00:39:29,100 去取车 762 00:40:03,700 --> 00:40:04,700 他被困在了这间屋子里 763 00:40:05,000 --> 00:40:06,400 从两面包抄把他往我这边赶 764 00:40:06,500 --> 00:40:07,000 明白 765 00:40:22,100 --> 00:40:22,800 不许动 766 00:40:26,100 --> 00:40:27,300 我一直在等着这个时刻的来临 767 00:40:29,300 --> 00:40:30,100 你太晚了 768 00:40:43,800 --> 00:40:44,900 很疼是吧？ 769 00:40:53,700 --> 00:40:54,300 杰克 770 00:40:55,100 --> 00:40:56,000 杰克你在干什么？ 771 00:40:56,700 --> 00:40:57,500 我们还能用得着他 772 00:41:04,200 --> 00:41:04,900 来吧 773 00:41:05,900 --> 00:41:06,800 杀了我 774 00:41:09,000 --> 00:41:10,300 也不会阻止导弹发射 775 00:41:12,000 --> 00:41:13,000 你在说什么？ 776 00:41:18,000 --> 00:41:19,700 你在说什么！？ 777 00:41:30,700 --> 00:41:32,400 杰克我们有麻烦了 778 00:41:33,400 --> 00:41:34,300 过来看看这个 779 00:41:34,700 --> 00:41:35,700 看好他 780

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Rbs1* in the *spl11* plants was also confirmed in the IR64 background ([Figure S4C](#pone.0087258.s004){ref-type="supplementary-material"}). ![Gene expression and protein accumulation patterns of *Rbs1, Spin1* and *Spl11* inthe *Rbs1 and Spin1* overexpression plants.\ **A.** Q-PCR analysis of the expression pattern of *Spin1* and *Spl11* in the *Rbs1* overexpression plants under LD and SD conditions. B. Expression of *Rbs1* in the *Spin1* overexpression and RNAi plants. C. Western blot detection of RBS1 and SPIN1 proteins in the *Spin1* overexpression and RNAi plants. RBS1 was detected using a native antibody. The SPIN1-TAP fusion protein was detected in the *Spin1*-OX plants using the PAP antibody. D. Western blot detection of RBS1 and SPIN1 proteins in the *Rbs1* overexpression lines; RBS1 and SPIN1 native antibodies were used in the immunoblot detection.](pone.0087258.g006){#pone-0087258-g006} Furthermore, we determined the protein levels of RBS1 and SPIN1 in the *Rbs1* and *Spin1* overexpression plants using anti-RBS1 and anti-SPIN1 antibodies. Western blot analysis showed that enhanced accumulation of the RBS1 protein was detected in the *Spin1* overexpression plants ([Figure 6C](#pone-0087258-g006){ref-type="fig"}) and that the accumulation of the SPIN1 protein was higher in the *Rbs1* overexpression plants ([Figure 6D](#pone-0087258-g006){ref-type="fig"}). We also detected that the RBS1 protein level was increased in the *spl11* mutant ([Figure S4D](#pone.0087258.s004){ref-type="supplementary-material"}), which is consistent with the expression data mentioned above. These results suggest that there is a positive relationship between RBS1 and SPIN1 but a negative relationship between SPL11 and RBS1. Discussion {#s4} ========== We identified RBS1 as a novel RNA binding protein of the hnRNP-R type in rice and showed that it interacts with SPIN1 in both yeast and rice protoplasts. To assess the functional relationship between *Rbs1* and *Spin1* in flowering time regulation in rice, we identified an *Rbs1* T-DNA insertion mutant and generated both overexpression and artificial microRNA transgenic plants of the *Rbs1* gene. Similar to the T-DNA mutant and the *Spin1* RNAi plants [@pone.0087258-VegaSnchez1], the *Rbs1* artificial microRNA plants did not show any difference in flowering time compared with the wild type plants in both LD and SD conditions (Data not shown). However, like the *Spin1* overexpression plants [@pone.0087258-VegaSnchez1], the *Rbs1* overexpression plants show late flowering under SD and LD conditions. Expression analysis showed that *Rbs1* overexpression leads to the suppression of both *Hd3a*, the rice florigen [@pone.0087258-Tamaki1]. Our results clearly demonstrate that RBS1 is a flowering suppressor that interacts with SPIN1, and this interaction could lead to regulate the expression of flowering genes in rice. Genome analysis showed that there are 196 RRM-containing proteins in *Arabidopsis* and 221 proteins in rice [@pone.0087258-Lorkovi1], [@pone.0087258-Morris1]. In rice, LOC\_*Os10g06130* also encodes an RRM-containing protein, which has 88% protein sequence similarity with RBS1. The expression of this gene is not affected in the *Rbs1* overexpression and artificial microRNA plants (data not shown). This gene may have redundantfunction with *Rbs1* in rice flowering, which might explain our observationthat the *rbs1* knockout mutant and artificial microRNA plants did not show any significant flowering time change under SD and LD conditions. In the *Rbs1* overexpression plants, the expression of *Spin1* is upregulated, which correlates with enhanced SPIN1 protein accumulation. We have previously shown that the *Spin1* overexpression plants flower later than the wild type Nipponbare plants under SD and LD conditions [@pone.0087258-VegaSnchez1]. In SD conditions, the expression of *Hd1* is reduced in the *Spin1* overexpression plants, indicating that SPIN1 influences flowering time via the Hd1 pathway in flowering-promoting conditions. However, in LD conditions, the *Hd1* expression, is the same in Nipponbare and *Spin1* overexpression plants [@pone.0087258-VegaSnchez1], suggesting that SPIN1 may target an unknown factor to regulate *Hd3a* under LD conditions. By contrast, in this study we found that the expression of *Hd1* is similar between the *Rbs1* overexpression and wild type Nipponbare plants under both LD and SD conditions ([Figure 5C](#pone-0087258-g005){ref-type="fig"}). Interestingly, in the *Rbs1* overexpression plants, the mRNA level of *Hd3a* is suppressed under both SD and LD conditions. These data suggest that RBS1 may function to regulate flowering in rice via the suppression of Hd3a-mediated mechanisms. Our previous study revealed the negative relationship between SPIN1 and SPL11 [@pone.0087258-VegaSnchez1]. In this study, we also found that the expression of *Spl11* is repressed in the *Rbs1* overexpression plants. In contrast, both the expression of *Rbs1* and accumulation of the RBS1 protein are increased significantly in the *spl11* mutant, indicating a negative relationship between RBS1 and SPL11. However, the direct relationship between these two proteins remains unclear. Yeast-two hybrid assays using SPL11 as the bait and RBS1 as the prey or vice versa did not detect any interaction between them (Vega-Sanchez and Wang, unpublished results). It is plausible that RBS1 is one of the components in the SPL11 protein complex and the interaction between RBS1 and SPL11 requires the presence of another protein that interacts with both proteins, for example SPIN1. Because RBS1 is a putative RNA binding protein and has RNA binding activity *in vitro*, it might be involved in RNA metabolism to regulate flowering time. In mammals, it has been recently shown that hnRNP-R binds to the 3′UTR of serotonin N-acetyltranferase and to the AU rich element of c-Fos mRNA to promote their degradation [@pone.0087258-Kim1], [@pone.0087258-Huang1]. Whether *Rbs1* is involved in mRNA turnover in rice needs to be determined in future studies. It is interesting to note that the putative ortholog of RBS1 in *Arabidopsis*, LIF2, is also involved in flowering time control [@pone.0087258-Latrasse1]. However, at this point, it is unclear whether LIF2 and RBS1 are functional homologs. LIF2 seems to be part of protein complex that regulates gene expression via epigenetic mechanisms [@pone.0087258-Latrasse1]. Whether RBS1 acts similarly to regulate flowering and other developmental pathways needs to be explored. Complementation studies of the *Arabidopsis lif2* loss-of-function mutants with the rice *Rbs1* gene should provide clues as to whether these pathways are conserved or not between the two species. Supporting Information {#s5} ====================== ###### **Identification of** ***Rbs1*** **by yeast two-hybrid screen in a rice cDNA library using the full length** ***Spin1*** **as the bait.** Numbers 72 and 69-2 are independent yeast clones containing the pDBleu-*Spin1* and pPC86-*Rbs1* constructs. Positive clones were identified by an X-GAL assay. (TIFF) ###### Click here for additional data file. ###### **Molecular analysis and flowering time of the** ***rbs1*** **mutant.** A. Structure of the T-DNA insertion. T-DNA was inserted into the fourth intron of Rbs1. Arrows indicate the primers used for analyzing the insertion site. LB and RB represent the left and right borders of T-DNA; B. PCR genotyping of the rbs1 mutant. DJ denotes Dongjin, 1 is a segregated wild type, 2 and 3 are homozygous plants and 4 is a heterozygous plant; C. Expression of Rbs1 for the plants in S3B; D. Flowering time of the rbs1 mutant under LD and SD conditions. (TIFF) ###### Click here for additional data file. ###### **Western blot analysis of the protein level of RBS1 in the** ***Rbs1*** **overexpression and wild type plants.** (TIFF) ###### Click here for additional data file. ###### **Expression analysis of** ***Rbs1*** **in the** ***Spin1*** **overexpression plants,** ***spl11*** **mutant plants and wild type Nipponbare (NPB) plants.** A. RT

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); peatlands (Hamilton and Hodder, 1978); interagency planning for energy resources (Fookes and Hutchinson, 1978); critique of report on Pureora forest plans (Fookes, 1978); environmental perception and planning (Ericksen, 1978); biological assessment of water quality (Hamilton, 1979); the aluminium debate (Ericksen, 1980); NZ lowland forests (Thompson, 1980); managing hazardous wastes (Penny, 1985); new environmental administration (Dixon and Gunn, 1986); and Ecopolitics III (Dixon, Gunn and Ericksen, 1988). ESU published the conference proceedings. ###### Environmental news Foundation ESU Executive member Keith Thompson (Biological Sciences) proposed in 1978 to establish a periodical titled Environmental News, which he would edit and publish. Between 1978 and 1984 there were 10 issues averaging seven items per issue all germane to environmental issues of the day (CEARS Proposal, 1989, Appendix 3, Environmental News, p2). ##### Resourcing ESU activities Clearly, Tom had helped spawn not only a very productive ESU, but also ideas for its continued development and success. Activities of ESU Executive members were, however, carried out over and above their required duties within respective departments and schools of study. There was no concession in workloads from departmental heads and every expectation that ESU members would research and publish in support of their departments. Fortunately, departments from which the ESU Executive Secretary was drawn supported secretarial functions and materials. Biological Sciences supported production of Environmental News edited by one of its staff, while Geography and Earth Sciences helped produce the wide range of documentation. Having conceded there was a resource need, the Vice-Chancellor provided a very small running grant ($350) in 1977. In trying to overcome the wider resource problem, ESU Executive members proposed in 1978 establishing an Environmental Studies Centre (ESC) (Fookes et al, 1978), hoping a stand-alone centre might attract internal and external funding. It failed to gain University support. In 1981, the unpaid part-time Director of ESU (Dr Gordon Edgar) made a formal approach to the Committee of Vice-Chancellor and Deans for funding of ESU activities and the running grant was increased to $1,200. To this point, the only external funds for ESU-supported activities had come for the Huntly Monitoring Project from 1975 to 1981, three Fulbright Fellows involved in teaching and community outreach (1977–1979), and some central and local government support for the Research Fellow directing FORLD in 1980. Thereon, ESU public outreach was carried voluntarily by ESU members. This piecemeal approach to resourcing its activities needed to change. By 1979, Council had formally recognized ESU, and as the Executive Officer, Tom Fookes had written its First Report to Council. He outlined the past history of ESU and its impressive achievements in the three years to 1979, much of it through voluntary staff contributions outside their disciplines. His report included the concern of ESU Executive members that 'no decision had been made on staffing and resourcing requirements to enable the Unit to continue to function' and concerns about 'a decision on who will teach Contemporary Environmental Issues in 1980'. This was followed by another report titled Request for Urgent Review of the Future of the Environmental Studies Unit. It highlighted the dimensions of the problem facing ESU and put forward several options, including: either implementing the Quinquennial Submission (Fookes et al, 1978); or inviting applications from senior staff to be Acting Director of the Unit's affairs. As it happened, ESU was rescued for the time being by the mostly externally funded FORLD research project in 1980. Thereon, the voluntary work of ESU Executive members continued, including developing the REP teaching programme. Nevertheless, to help relieve the pressure of voluntary contributions and to advance the cause of interdisciplinary environmental research, the ESU Executive in 1989 once again proposed establishing of a stand-alone centre with capacity to compete for external funds. Meanwhile, Tom Fookes had left The University of Waikato in 1983 to be an environmental assessment officer in the South Australian Department of Environment and Planning. In 1987, he became a senior policy analyst in the new Ministry for the Environment (MfE) in Wellington. The latter enabled him to reconnect with his former colleagues at The University of Waikato, especially where their projects drew on MfE information and support. #### 3. Centre for Environmental and Resource Studies Some 10 years after ESU's proposal for an Environmental Studies Centre (ESC), members put forward a new proposal. The Centre for Environmental and Resource Studies (CEARS) differed markedly from its predecessor, reflecting the evolving nature of the broad field of study from emphasis on resource development in the 1960s to emphasis on environmental quality in the 1970s, to emphasis on a balanced approach to resource development and environmental quality from an interdisciplinary perspective (CEARS Proposal, 1989, Appendix 4, Previous ESU Proposals for a Centre, pp21–22). With support of the departments contributing to the REP teaching programme, a proposal for CEARS was prepared by me as ESU Secretary.2 The CEARS business plan was adopted by the University Council on 23 August 1989, but the Vice-Chancellor held firm to his view that CEARS be administratively located within a school. He invited me, a geographer, to be founding director of CEARS. As Geography was within the School of Social Sciences, administrative responsibility for CEARS came under the Dean of Social Sciences, with physical location in the Department of Geography. This would soon cause problems for the REP multidisciplinary programme, as explained later in section 4. In many respects, CEARS took over the functions and aims of ESU, but with the added aim to 'Develop research proposals for contracts with outside agencies so that CEARS moved towards being a financially self-sustaining venture within the university' (CEARS Proposal, 1989, p7; Calendar, 1991, p385). For the first year in 1990, both CEARS Director and Secretary were half-time. A large CEARS Management Committee involved senior staff from all interested departments, in effect cutting out former ESU members. Even though the CEARS Plan had its Director as co-ordinator of the REP programme and teaching in it, the three schools supporting REP were unwilling to provide a modest grant of $15,000 each to support this activity. Indeed, not only was the CEARS Director soon instructed not to be the overall co-ordinator of REP, but also that CEARS was not to enrol postgraduate New Zealand students to engage in its research projects. To overcome this loss of a potential income stream, CEARS, at the suggestion of the Dean of Social Sciences, established a higher degrees programme for full-fee-paying international students, which proved successful. When new school-based environmental programmes were proposed in 1991 without reference to other interested parties, I requested the Dean of Social Sciences to draw together all parties to discuss emerging problems for REP and CEARS and other cross-school research centres, noting: ... a problem reflecting the administration and funding arrangements that ties subjects (disciplines) and centres to specific Schools of Study. While these arrangements suit school-specific subjects, and interdisciplinary work clearly within one school, they do not serve well inter-school programmes, such as CEARS, SMER, and CMSR... In part as a response to attempts at curtailing CEARS activities, I submitted a detailed Strategic Plan to the CEARS Management Committee, including provision for a Deputy Director. Its main thrust was for externally funded research (and a smaller and more relevant management committee). Filling the role, Dr Richard Warrick brought with him an internationally funded three-year contract on policy options for Bangladesh under a changing climate. So commenced a fruitful stream of international and national contracts for environmental research and training, including two long-running FRST-funded proposals on climate change (CLIMPACTS) and planning under co-operative mandates (PUCM). In 1996, a new dean sought to not only claw back the Director's salary (which stemmed from my having been in Geography), but also dramatically increase overheads on CEARS contracts. This was a monumental impediment to successful pursuit of our higher degrees programme and interdisciplinary research and training. In response, a proposal was put to the new Vice-Chancellor (Bryan Gould) for CEARS to become independent of any school in return for which the centre would become fully self-funded and trade under a new name. By the year 2001, the International Global Change Institute (IGCI) had grown to 13 effective full-time staff funded externally – including for the Director and Deputy. In the meantime, what happened to the environmental teaching programme? #### 4. Proliferation of environmental programmes By the early 1990s, a number of departments in The University of Waikato had interest in the 'environment', the word now featuring in course titles of at least eight departments across four schools. On one hand, this was seen as an increasing number of staff recognizing 'environment' as an important disciplinary concern. On the other hand, it was seen as jumping on the 'environmental bandwagon' in order to grow school and departmental enrolments and thereby funding. It was likely some of each. Because the REP programme was embedded in three schools of study, it seemed not so isolated as to be open to attack by traditional interests. However, the ink was hardly dry on the CEARS Plan when only two months after it was approved by the University Council, lobbying started for competitive environmental programmes. This is not to say there was no room for 'alternative'

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only text height, not the whole image. * IE8: * This method is only partially supported. Only one rectangle is returned which begins at the top left corner for the first selected row, and ends at the bottom right corner of the last selected row. * There is known bug when text is wrapping to next line returned rect doesn't match selection [#1895](https://github.com/ckeditor/ckeditor4/issues/1895). HIV progression at a standstill Although most people that get infected with HIV develop AIDS, rare individuals maintain immune function in the presence of virus, a phenomenon also seen in natural hosts of the closely related SIV. Muenchhoff et al. describe a cohort of pediatric HIV patients who have normal CD4 T cell counts, despite high viremia and lack of antiviral treatment. These children have low immune activation, including less chemokine receptor CCR5 expression on central memory CD4 T cells, similar to sooty mangabeys infected with SIV. The immune mechanisms described in these patients shed light on HIV pathogenesis, which may help develop future treatments.Olympian Suzy Favor Hamilton was one of the country's greatest runners—she was also a high-priced call-girl. Why would a woman with so much to lose choose to play that game? Curled into the corner of a plush sofa in the lobby of a hotel in Chippewa Falls, Wisconsin, three-time Olympian Suzy Favor Hamilton was fielding questions from the starstruck president of the local all-ages track club before taking the stage as the honorary guest at the group's February 2012 awards banquet. One of America's fastest-ever female middle-distance runners, and a representative for Reebok and Nike at the pinnacle of her career, Favor Hamilton is beloved here in her home state as much for her readiness over the past quarter century to pop up cheering at charity runs and promote locally produced soy sauce and green beans as she is for her athletic prowess. Dressed for the event in an elegant black sweater and knee-high black boots—her slightly sidelong, wry grin dazzling as ever—she gamely ticked off her career highlights for the club's president, Wade Zwiener: winning 11 Wisconsin state high school titles; snagging an unprecedented nine NCAA titles at the University of Wisconsin, and, of course, making it to the Olympics—"something I'd trained for since I was a little girl." More From ELLE Since her retirement from professional competition in 2006 at 37—with a body "almost like an 80-year-old, from all the running I've done," as she's said—she's been running three to five miles five days a week, she told Zwiener, which is the sweet spot that "seems to keep me injury-free." She's been open in recent years about her use of Zoloft and therapy to combat depression, but on this night she was effusive about her sport's mental-health benefits, calling running "the magic drug for me my entire life." And she was funny, putting her finger to her chin, Diane Sawyer–style, at one point to purr (as well as a woman with a strong heartland twang can), "What do you think running brings, Wade? Let's turn the tables." Zwiener giggled: "No, I totally agree with you—[it helps with] the mood-type stuff. And it helps keep the beer gut off middle-aged guys like me." Wrapping up, Zwiener expressed humble thanks: "I just thought, Ya know, when am I going to get the chance to talk to Suzy Favor Hamilton? It's awesome!" And with that, Favor Hamilton jumped up, spun Zwiener around in his seat to face his buddy standing by with a camera, and bent down to give him a big kiss on the cheek. "Did we get that?" she said, laughing, to the camera guy. "Oh, jeez," said Zwiener, adjusting his glasses and blushing. "I'm going to frame that one. I mean, jeez!" Favor Hamilton's flirty buss, while charming, seemed oddly prefeminist, in the fashion of a 1950s starlet dishin' out a dash of sauce—except perhaps when she gushed to Zwiener about recently having won the Rock 'n' Roll "stiletto race" in Vegas: "In my bra, too!…They were like, 'She is a go-getter!'…If you google the stiletto race, you'll get to see parts of it." Looking back a year later, however, the truly surreal moment of the encounter came when Zwiener asked Favor Hamilton what she'd been up to lately. "A lot," she replied, nodding wide-eyed. As much of the world now knows, in addition to selling real estate and raising a daughter, now seven, with her husband, Favor Hamilton at the time was working as a $600-per-hour call girl, scheduling dates in Las Vegas, Chicago, Los Angeles, and elsewhere. When a reporter for The Smoking Gun—presumably tipped off by one of her clients—confronted Favor Hamilton in the lobby of a Las Vegas hotel early last December, she initially denied involvement with Haley Heston's Private Collection, billed on its now dismantled website as "the premier Boutique Escort Agency of Las Vegas." Yet when the reporter showed Favor Hamilton, who used the curiously midwestern white-bread alias Kelly Lundy, evidence to the contrary, likely from the escort agency's tweets, the once mighty athlete crumpled. She said her husband, Mark Hamilton, a former University of Wisconsin baseball player whom she met her freshman year of college and married a week after graduation, knew about her work but didn't approve. And she never thought she'd get caught, she said, because, well, Tiger Woods, "the biggest athlete ever, obviously thought he could never get caught." The Smoking Gun story broke on December 20. Later the same day, Favor Hamilton released a series of Twitter posts explaining that she'd been drawn to escorting "because it provided many coping mechanisms for me when I was going through a very challenging time with my marriage and my life." In her carefully worded mea culpa (wisely, she skipped the Tiger Woods comparison here), she wrote: "I do not expect people to understand. But the reasons for doing this made sense to me at the time and were very much related to depression." The news of Favor Hamilton's double life—in the escort promo pictures that raced across the Internet, "Kelly" was shown crouching in stilettos or standing on a bed in a black bikini, her face always strategically concealed—prompted predictable commentary about the lamentable state of modern marriage, as well as equally predictable briefs in defense of prostitution as sex among consenting adults. The exposé also inspired a bumper crop of lewd jokes and who knows how many idle fantasies (three married women I know had dreams about flying to meet strange men for sex after hearing of Favor Hamilton's exploits). Then came the press releases: Disney, Foot Locker, and the Rock 'n' Roll Marathon Series quickly dropped Favor Hamilton as an endorser. Even the Wisconsin Potato & Vegetable Growers Association no longer wished to have the tarnished athlete beaming over a bowl of spuds in its ads. While Favor Hamilton has obviously struggled with depression—this wasn't the first time she'd spoken publicly about it—what she did remains astonishing to many. She was, after all, a much-admired woman with a young daughter, a lovely home in Madison, and flourishing real estate and motivational-speaking businesses. How could she do something so risky for herself and her family? (The Las Vegas police are not investigating Favor Hamilton, according to a department spokesman, though she could still be vulnerable to federal prosecution for sex trafficking across state lines.) Yet with every fresh tale of an athlete flaming out spectacularly—and, lately, with Manti Te'o, Oscar Pistorius, Lance Armstrong, and, yes, Suzy making headlines, there have been a slew of them—we're forced to acknowledge that the same qualities that make elite athletes great may also contribute to their downfall. Advertisement - Continue Reading Below Favor Hamilton's path as a runner began with a simple, joyful insight she had as a girl. Growing up in Stevens Point, Wisconsin, she loved to play on a string of wooded trails beside the banks of the Plover River, racing to collect branches to build forts with her older brother and two older sisters. "Pretty soon I'd be galloping," she once said. "I remember that it felt so easy, running like that for hours. I actually pretended that I was a horse." With coaching from her father, Suzy ran her first big race, a 400 meter, in fifth grade. She shot past all the girls, then all the boys. And blazing into the finish, she heard spectators shouting "Su-zy! Su-zy! Su-zy!" That was the moment, she's said, that got her hooked. Reaping more medals than any other Wisconsin runner (again, boy or girl) while in high school, she became known as a wunderkind, genetically gifted with extraordinary lung capacity and a kick (track speak for finishing speed).""When the gun fired, she just sprang out like a ball of muscle," recalls Madison writer Ruth Conniff, who ran against Favor Hamilton in high school meets in

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jewels, Isabella Court (W. D. Bordeaux, 1929), is located on the northwest corner of Isabella and Main. **ISETTA:** Italian motorcycle designer Renzo Rivolta of Iso Rivolta began manufacturing this tiny vehicle in 1952. Meaning "Little Iso" this car was truth in advertising as it measured only 90" by 54" and had a top speed of 53 MPH. BMW obtained a license to manufacture them in Germany and produced 160,000 between 1955 and 1962. (See **Corvette.) 14** **» ISETTA: They really were small** **ISOLDE:** Named for the heroine of a medieval love story, Isolde the Fair is the lover of Sir Tristram. Following an estrangement, Tristram is wounded in battle. He sends for Isolde but dies of despair when he believes she is not coming. Of course Isolde arrives, finds Tristram dead and dies of a broken heart. **IVANHOE:** He is a knight in Sir Walter Scott's romantic novel of the same name set in 12th century England. **IWO JIMA:** This is a volcanic island in the western Pacific Ocean. During WW II there was a large Japanese air base here. The battle was one of the bloodiest of the Pacific campaign. The United States Marine Corps captured the island following a two-month (February-March, 1945) siege. Five marines placed an American flag on its highest point, Mount Suribachi, following the victory. Photographer Joe Rosenthal captured the moment on film. This Pulitzer Prize winning photograph is one of the most famous images of the War. ### "BOULEVARD OF HUNDREDS OF BENEFITS" During the 1990s as Houston's Asian population increased dramatically, City Council voted to allow street signs in Chinese and Vietnamese to be placed on poles underneath the street's English name. (For unknown reasons a 2001 proposal to allow Koreatown to do the same was denied.) The purpose was to assist this influx of immigrants to find their way around. The rule was the Asian word had to be close to either the meaning of the existing street name or phonetically sound like the English street. So if you are driving in Chinatown or Little Saigon look for these signs: **Bellaire** – _Bai Li_ – Boulevard of Hundreds of Benefits **Harwin** – _Hao Yun_ – Good Luck **Clarewood** – _Wu De_ – Martial Arts **Wilcrest** – _Wei Dao_ – Traditional Moral Principles **Milam** – _Nguyen Hue_ – Vietnamese king symbolizing patriotism **West Gray** – _Hai Ba Trung_ – Vietnamese queens, Trung sisters, who defeated the Chinese in the 1st century A. D. **Anita** – _An Loc_ – Battlefield site during Viet Nam War **Elgin** – _Yen Do_ – Academic Excellence **Holman** – _Hung Vuong_ – First King of Viet Nam **Travis** – _Tu Do_ – Freedom ## J **J. B. LEFEVRE:** He held the positions of City Manager and Finance Director of Baytown. **** **J. R. TOWLES:** Justin Richard Towles was born in Crosby, Texas, a small community east of Lake Houston. A talented baseball player he was drafted by the Houston Astros in 2004. He worked his was up through the Houston farm system and made his major league debut as a catcher on September 5, 2007. Fifteen days later he chalked up 8 runs batted in, a new Astro record. The street, Sunnyview Way, that ran in front of his childhood home, was renamed in his honor in 2007. **** **JACINTOPORT:** At the end of this street is a 62-acre terminal facility fronting on the Houston Ship Channel and operating under the Port of Houston Authority. It is a cargo handling and stevedoring firm. **JACK JOHNSON:** Arthur John "Jack" Johnson was the best heavyweight boxer of his generation and the first black heavyweight champion. His record was 73-13-9-9 (wins, losses, draws and no decisions). Born in Galveston in 1878, he entered the ring as a young man and by 1902 had won 50 fights. He won the heavyweight belt in 1908, knocking out Tommy Burns, a white man, in a 14 round fight in Australia. To say the least this did not sit well with the white population in the pre-civil rights era. Like many athletes today his flamboyant lifestyle got him in trouble with the law. In his case, violating the Mann Act (transporting women across state lines for immoral purposed). He served a prison term for this. Johnson lost his title in a bout with white challenger, Jess Willard, in 1915. He was killed in a car wreck in 1946. **** **JACK LONDON:** He was an American who wrote novels and short stories whose main theme was the 1849 Yukon gold rush. His real name was John Griffith. Among his greatest and most readable works are _Call of the Wild_ and _White Fang_. **** **JACK:** Baytown developer W. E Defee named three streets for his children: **Jack, James** and **Murrill.** (See **Defee.) 5** **JACKSON BAYOU:** This street and the 3.5 mile watercourse that meanders through Crosby, Texas are named for Humphrey Jackson. An Irish lawyer, he came to America in 1808 and settled on a sugar plantation in Louisiana. He fought at the Battle of New Orleans. Jackson moved to Texas in 1823 to join Stephen F. Austin's colony. Because of his legal background he became active in local government. He was killed by a falling tree while clearing his land in 1833. **, ** **JACKSON:** Abner – This Virginian and his business partner, James Hamilton, a former governor of Virginia, came to Texas in 1838 after suffering some business reversals in their home state. In 1844 the partners started Retrieve Plantation in Brazoria County. Jackson built Darrington Plantation nearby and founded the town of Lake Jackson. Things were going well until the War Between the States brought disaster to the plantation economy. He died in 1861 a broken man. **** **» JACKSON: Abner Jackson Plantation House** **JACKSON:** This is one of several area streets we have named for a U.S. President. Andrew Jackson was the 7th American to hold the nation's highest office. **** **JACKSON:** This road is named for another lumber town in Montgomery County that faded away as the timber industry diminished in that area. Located on the Chicago, Rock Island & Pacific Railroad, Jackson received a post office in 1910 but saw it closed 15 years later. By 1946 it was a ghost town. **** **JAMES BOWIE:** Jim Bowie is revered by Texans for his heroic death at the Battle of the Alamo on March 6, 1836. He is eulogized by the Kingston Trio in their moving 1959 rendition of Texan Jane Bower's song _Remember the Alamo:_ "Jim Bowie lay dying but his powder was ready and dry/Flat on his back Bowie killed him a few in reply." He is also remembered for his invention of the famous Bowie Knife. When he first arrived in Texas he searched futilely for lost treasure near the San Saba River, seeking what is known today as the Lost Bowie Mine. **** **JAMES:** (See **Jack.** ) **JANE LONG:** She is known as the "Mother of Texas" because she bore the first child of Anglo descent on Texas soil. Long was also a member of Stephen F. Austin's Old Three Hundred. **** **JARDIN:** One of developer Edward Crain's favorite places in the world was the Tuileries Gardens in Paris, France. They are probably the finest existing example of formal French gardens. Landscape architect Andre Le Notre designed them in the 1600s as part of the grounds of a palace for Catherine de Medici. Crain used the French word for garden to name this Southside Place street to remind him of this beautiful place. **** **JARRARD:** Ed J. – This gentleman was a real estate developer in West University Place in the 1920s. His partner was Preston R. Plumb. (See **Plumb.) 14** **JEAN LAFITTE:** Called everything from a bloody buccaneer to a gentleman privateer, Lafitte is one of Texas' more colorful characters. In fact no one knew the truth about the man called the "Prince of Pirates." His early life is a mystery but we do know he led a group of smugglers stationed at his stronghold in Barataria, south of New Orleans, from 1810 until 1814. In 1814 he and his men joined with General Andrew Jackson to defeat the British army at the Battle of New Orleans, allowing the Americans to win the War of 1812. For his valorous actions President James Madison pardoned him and his sailors of all crimes they had been accused of committing. In 1817 Lafitte moved his operations to Galveston Island. Unfortunately, some of his subordinates attacked American ships and the government put a price on his head. Not wanting a confrontation with the U.

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.hops.hopsworks.util.Helpers; import io.hops.hopsworks.util.JavascriptExec; import io.hops.hopsworks.util.models.User; import org.openqa.selenium.By; import org.openqa.selenium.NoSuchElementException; import org.openqa.selenium.WebDriver; import org.openqa.selenium.WebElement; import org.openqa.selenium.support.ui.Select; import java.util.Random; import java.util.concurrent.TimeUnit; import static org.junit.Assert.assertEquals; public class RegistrationHelper { public static final String EMAIL_VALIDATION_URL = "hopsworks-admin/security/validate_account.xhtml?key="; public static final String ADMIN = "HOPS_ADMIN"; public static final String USER = "HOPS_USER"; private static void gotoRegisterPage (WebDriver driver) { driver.manage().timeouts().implicitlyWait(1, TimeUnit.SECONDS); try { driver.findElement(By.name("registerForm")); } catch (NoSuchElementException | Error e) { driver.findElement(By.linkText("Register")).click(); } driver.manage().timeouts().implicitlyWait(WebDriverFactory.IMPLICIT_WAIT_TIMEOUT, TimeUnit.SECONDS); } private static void registerTest(String firstName, String lastName, String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { boolean twoFactorEnabled = dbHelper.isTwoFactorEnabled(); if (twoFactor &&!twoFactorEnabled) { Helpers.enableTwoFactor(driver, dbHelper); gotoRegisterPage(driver); } Helpers.waitForElement(By.name("registerForm"), driver); driver.findElement(By.name("first_name")).sendKeys(firstName); driver.findElement(By.name("last_name")).sendKeys(lastName); driver.findElement(By.name("user_email")).sendKeys(email); driver.findElement(By.name("phone_number")).sendKeys("1234567890"); driver.findElement(By.id("id-password")).sendKeys(password); driver.findElement(By.name("user_password_confirm")).sendKeys(password); Select seqQA = new Select(driver.findElement(By.name("sec_question"))); seqQA.selectByVisibleText("Name of your first pet?"); driver.findElement(By.name("sec_answer")).sendKeys("pet"); driver.findElement(By.name("user_agreed")).click(); WebElement testUserElement = driver.findElement(By.name("test_user")); JavascriptExec.jsClick(driver, testUserElement); if (twoFactor) { driver.findElement(By.name("2FactorAuth")).click(); } driver.findElement(By.name("registerForm")).submit(); } private static void register(String firstName, String lastName, String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { gotoRegisterPage(driver); registerTest(firstName, lastName, email, password, twoFactor, driver, dbHelper); if (twoFactor) { assertEquals("Four steps, and you're there...", driver.findElement(By.id("two_factor_four_steps")) .getText()); driver.findElement(By.linkText("Ok")).click(); } else { Helpers.waitForElementVisibility(By.id("regSuccess"), driver); String successAttr = driver.findElement(By.id("regSuccess")).getAttribute("aria-hidden"); String errorAttr = driver.findElement(By.id("regError")).getAttribute("aria-hidden"); //assert no error msg assertEquals("true", errorAttr); assertEquals("false", successAttr); driver.findElement(By.linkText("Sign in")).click(); } } public static String registerUserTest(boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); String email = firstName + "@hopsworks.ai"; String password = "12345Ab"; registerTest(firstName, lastName, email, password, twoFactor, driver, dbHelper); return email; } public static String registerUser(boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); String email = firstName + "@hopsworks.ai"; String password = "12345Ab"; register(firstName, lastName, email, password, twoFactor, driver, dbHelper); return email; } public static void registerUser(String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); register(firstName, lastName, email, password, twoFactor, driver, dbHelper); } public static String registerUser(String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { Random rand = new Random(); String firstName = "user_" + rand.nextInt(100000); String lastName = "user_" + rand.nextInt(100000); String email = firstName + "@hopsworks.ai"; register(firstName, lastName, email, password, twoFactor, driver, dbHelper); return email; } public static void validateEmail(String key, WebDriver driver) { Helpers.driverGet(EMAIL_VALIDATION_URL + key, driver); assertEquals("You have successfully validated your email address, but your account still has to be approved " + "by an administrator. Hopefully soon!", driver.findElement(By.xpath( "(.//*[normalize-space(text()) and normalize-space(.)='Email Address Verification'])[1]/following::p[1]")) .getText()); } public static User createActivatedUser(String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { String email = registerUser(password, twoFactor, driver, dbHelper); User user = validateAndActivateUser(email, driver, dbHelper); Helpers.driverGet("hopsworks", driver); return user; } public static User createActivatedUser(String email, String password, boolean twoFactor, WebDriver driver, DBHelper dbHelper) { registerUser(email, password, twoFactor, driver, dbHelper); User user = validateAndActivateUser(email, driver, dbHelper); Helpers.driverGet("hopsworks", driver); return user; } public static User validateAndActivateUser(String email, WebDriver driver, DBHelper dbHelper) { User user = dbHelper.getUserByEmail(email); String key = dbHelper.getValidationKey(user.getEmail()); validateEmail(key, driver); dbHelper.activateUser(email); dbHelper.addGroup(user, USER); return user; } public static User createAdminUser(String password, WebDriver driver, DBHelper dbHelper) { User user = createActivatedUser(password, false, driver, dbHelper); dbHelper.addGroup(user, ADMIN); return user; } } source include/have_sjis.inc; source include/master-slave.inc; --disable_warnings drop table if exists t1; drop procedure if exists p1; --enable_warnings create table t1 (a varchar(255) character set sjis); create procedure p1 (in a varchar(255) character set sjis) insert into t1 values (a); SET NAMES binary; CALL p1 ('–\\'); select "--- on master ---";

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, August 2015, table E.1. The estimated participation rates are not directly comparable between 2007 and 2013 because of revisions to the methodology. [12] For more information, see Stacy Dean and Dorothy Rosenbaum, “SNAP Benefits Will Be Cut for Nearly All Participants in November 2013,” Center on Budget and Policy Priorities, revised August 2, 2013, http://www.cbpp.org/cms/?fa=view&id=3899. [13] Neither of these two changes to states’ eligibility rules resulted from recent legislation. Both are state options from the 1996 welfare law. The Recovery Act suspended the three-month time limit for the rest of 2009 and 2010, but because of the high unemployment associated with the recession, most areas already were eligible for a waiver under longstanding rules. In January 2009 the Bush Administration clarified that states qualifying for the new Emergency Unemployment Compensation program would be treated the same as states qualifying for the Extended Benefits unemployment insurance program, which were eligible for statewide waivers under existing law. For more information on these two provisions, see Dorothy Rosenbaum, Stacy Dean, and Robert Greenstein, “Cuts Contained in SNAP Bill Coming to the House Floor Would Affect Millions of Low-Income Americans,” Center on Budget and Policy Priorities, revised September 17, 2013, http://www.cbpp.org/research/cuts-contained-in-snap-bill-coming-to-the-house-floor-would-affect-millions-of-low-income. [14] See Peter Ganong and Jeffrey B. Liebman, “The Decline, Rebound, and Further Rise in SNAP Enrollment: Disentangling Business Cycle Fluctuations and Policy Changes,” National Bureau of Economic Research, Working Paper 19363, August 2013, http://www.nber.org/papers/w19363.pdf?new_window=1. CBO estimates from the 2014 farm bill debate also confirm that a relatively small share of SNAP participants’ eligibility depends on these two rules. According to CBO, expanded categorical eligibility in all states, including those that adopted it before 2009, accounts for only about 2 percent of program costs. CBO also estimated that eliminating all waivers from the three-month time limit (not just those for areas with high unemployment because of the recession) would have cut SNAP participation in 2014 by less than 4 percent. [16] In 2007 8.8 percent of the population received SNAP benefits. The share peaked at about 15 percent in 2013. Based on CBO’s SNAP projections and the Census Bureau’s population projections, the share will fall to 9.5 percent in 2026. [17] In addition to the economy and SNAP-related policy changes, other factors will need to be considered in assessing caseload trends. For example, state implementation of the Affordable Care Act, which expanded Medicaid eligibility in many states and induced virtually every state to revise its automated eligibility systems and processes, may have indirectly affected SNAP enrollment in some states. [19] Ganong and Liebman, op. cit.; James P. Ziliak, “Why Are So Many Americans on Food Stamps?” in J. Bartfeld et al., editors, SNAP Matters: How Food Stamps Affect Health and Well Being, Stanford University Press, 2015; Marianne Bitler and Hilary Hoynes, “The More Things Change, the More They Stay the Same? The Safety Net and Poverty in the Great Recession,” Journal of Labor Economics, Vol. 34, Issue S1, 2016; and Jacob Alex Klerman and Caroline Danielson, “Can the Economy Explain the Explosion in the Supplemental Nutrition Assistance Program? An Assessment of the Local-level Approach,” American Journal of Agricultural Economics, 2016. [21] The decline in the unemployment rate over much of this period overstated the improvement in the labor market. Because people continued to drop out or stay out of the labor force even as the economy recovered, the share of the population age 16 and over with a job (the employment rate) has risen only modestly from its recession low. As Federal Reserve Chair Janet Yellen said in December 2015 when announcing the Federal Reserve was beginning to raise interest rates, “I continue to judge that there remains slack in the economy, margins of slack that are not reflected in the standard unemployment rate, and, in particular, I’ve pointed to the depressed level of labor force participation and also the somewhat abnormally high level of part-time employment.” See Federal Reserve Board of Governors, “Transcript of Chair Yellen’s Press Conference,” December 16, 2015, http://www.federalreserve.gov/mediacenter/files/fomcpresconf20151216.pdf.Thornbury Castle is a magnificent retreat located in South Gloucestershire that is proudly proclaimed to be the only Tudor castle to presently operate as a hotel, a unique novelty that serves as a powerful selling point. As someone who recently stayed at the castle I can personally endorse Thornbury as an incredible place to visit and should be added to the bucket list of all who read this. The History In July 1510 Edward Stafford, 3rd Duke of Buckingham, obtained a royal licence to undertake work at his manor of Thornbury, located on the edge of the Cotswolds. The manor had been in the Stafford family for generations and the ambitious duke sought to transform his pleasant retreat into a palatial home without rival anywhere else in the kingdom. The proud and arrogant Buckingham was a descendant of the Plantagenet kings of England and had an impeccable bloodline through which he was not only well-connected, but also exceptionally wealthy. Nonetheless he had effectively been exiled from holding any power at court due to the pre-eminence of Cardinal Thomas Wolsey and the king’s favourites such as Charles Brandon and William Compton. With an egotistical desire to attract attention and with money to burn, Buckingham set about a building campaign that would ensure his castle would be the grandest noble home in the kingdom. The reasons for Buckingham’s desire to base himself at Thornbury, as opposed to one of his many other estates throughout England, are unclear but may be connected in part to his childhood. The duke’s father, Henry Stafford, 2nd Duke of Buckingham, had been an ally of Richard, Duke of Gloucester, in 1483 and helped Gloucester claim the throne as Richard III. Within months the 2nd Duke turned against his king and launched a farcical rebellion to unseat Richard. After the collapse of his uprising the duke was captured and summarily executed in Salisbury. The young Edward Stafford’s uncertain future was somewhat secured when the seven-year-old’s wardship was given to Margaret Beaufort in 1486, the mother of the new king Henry VII and the esteemed matriarch of the Tudor Dynasty. It is a possibility Margaret placed the young boy at Thornbury Manor, a claim lent credence when taken into consideration the marriage of the duke’s mother Katherine Wydeville to Jasper Tudor, Duke of Bedford and uncle to the king. It is known that Jasper based himself at Thornbury and would die there on 21 December 1495. His ghost is stated to roam the property. After a childhood spent in close companionship with the royal family, Edward Stafford emerged into adulthood as a strong-headed and ostentatious character fully aware of his noble grandeur. It was such a boastful disposition that would inspire Thornbury Castle which was designed to rival the king’s own Hampton Court Palace as the greatest home in the kingdom. Attempting to upstage the king however was not a recommended tactic. Work was still ongoing in 1521, more than a decade after it had commenced, when the arrest of the duke suddenly caused tools to be downed and construction halted. The duke’s crime had been to rouse suspicion of treason in the mind of the increasingly paranoid king he had attempted to upstage – Henry VIII. By 1521 the king was entering his 30’s and had yet to produce a legitimate male heir. Thoughts were slowly beginning to form about the event of a succession crisis and many were allegedly turning their heads towards the Duke of Buckingham, who it may be argued had a greater claim to the throne than Henry VIII. A foreign ambassador stated admiringly ‘my lord of Buckingham, a noble man and would be a royal ruler’. Furthermore the duke possessed substantial wealth, evident from his transformation of Thornbury into a palatial home. The king’s finances meanwhile were in disarray and the treasury empty. The combination of these factors left Buckingham exposed to the king’s ruthless nature, which erupted in April 1521 when the duke was summoned to court and placed in the Tower of London. His downfall was swift; he was charged with intending to kill the king and executed on Tower Hill on 17 May. His wealth and property, including Thornbury Castle, was seized by the crown and became King Henry VIII’s. After this period the castle was occasionally used by the king’s daughter Mary, who would regularly stay in Thornbury during her teenage years whilst she was a student of the Bishop of Exeter. It was during the summer of 1535 however that the castle received notoriety when Thornbury played host to King Henry VIII and his new queen Anne Boleyn for 10 days. The pair arrived on 14 August and departed to Acton Court on 22 August, the 50th anniversary of the Tudors accession to the throne at Bosworth Field. Whilst at Thornbury Henry was visited by a delegation from nearby Bristol who brought him 10 oxen and 40 sheep whilst Anne was presented with a

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the smoothing inertial projection neural network (SIPNN) algorithm for solving the proposed general model. Under certain conditions, the proposed algorithm can converge to a stationary point. Finally, convergence behavior and successful recover performance experiments and a comparison experiment confirm the effectiveness of the proposed SIPNN algorithm.// clang-format off // This source file is part of the Swift.org open source project // // Copyright (c) 2014 - 2015 Apple Inc. and the Swift project authors // Licensed under Apache License v2.0 with Runtime Library Exception // // See http://swift.org/LICENSE.txt for license information // See http://swift.org/CONTRIBUTORS.txt for the list of Swift project authors // /* CFPreferences.h Copyright (c) 1998 - 2015 Apple Inc. and the Swift project authors */ #if!defined(__COREFOUNDATION_CFPREFERENCES__) #define __COREFOUNDATION_CFPREFERENCES__ 1 #include <CoreFoundation/CFBase.h> #include <CoreFoundation/CFArray.h> #include <CoreFoundation/CFString.h> CF_IMPLICIT_BRIDGING_ENABLED CF_EXTERN_C_BEGIN CF_EXPORT const CFStringRef kCFPreferencesAnyApplication; CF_EXPORT const CFStringRef kCFPreferencesCurrentApplication; CF_EXPORT const CFStringRef kCFPreferencesAnyHost; CF_EXPORT const CFStringRef kCFPreferencesCurrentHost; CF_EXPORT const CFStringRef kCFPreferencesAnyUser; CF_EXPORT const CFStringRef kCFPreferencesCurrentUser; /* NOTE: All CFPropertyListRef values returned from CFPreferences API should be assumed to be immutable. */ /* The "App" functions search the various sources of defaults that apply to the given application, and should never be called with kCFPreferencesAnyApplication - only kCFPreferencesCurrentApplication or an application's ID (its bundle identifier). */ /* Searches the various sources of application defaults to find the value for the given key. key must not be NULL. If a value is found, it returns it; otherwise returns NULL. Caller must release the returned value */ CF_EXPORT CFPropertyListRef CFPreferencesCopyAppValue(CFStringRef key, CFStringRef applicationID); /* Convenience to interpret a preferences value as a boolean directly. Returns false if the key doesn't exist, or has an improper format; under those conditions, keyExistsAndHasValidFormat (if non-NULL) is set to false */ CF_EXPORT Boolean CFPreferencesGetAppBooleanValue(CFStringRef key, CFStringRef applicationID, Boolean *keyExistsAndHasValidFormat); /* Convenience to interpret a preferences value as an integer directly. Returns 0 if the key doesn't exist, or has an improper format; under those conditions, keyExistsAndHasValidFormat (if non-NULL) is set to false */ CF_EXPORT CFIndex CFPreferencesGetAppIntegerValue(CFStringRef key, CFStringRef applicationID, Boolean *keyExistsAndHasValidFormat); /* Sets the given value for the given key in the "normal" place for application preferences. key must not be NULL. If value is NULL, key is removed instead. */ CF_EXPORT void CFPreferencesSetAppValue(CFStringRef key, CFPropertyListRef value, CFStringRef applicationID); /* Adds the preferences for the given suite to the app preferences for the specified application. To write to the suite domain, use CFPreferencesSetValue(), below, using the suiteName in place of the appName */ CF_EXPORT void CFPreferencesAddSuitePreferencesToApp(CFStringRef applicationID, CFStringRef suiteID); CF_EXPORT void CFPreferencesRemoveSuitePreferencesFromApp(CFStringRef applicationID, CFStringRef suiteID); /* Writes all changes in all sources of application defaults. Returns success or failure. */ CF_EXPORT Boolean CFPreferencesAppSynchronize(CFStringRef applicationID); /* The primitive get mechanism; all arguments must be non-NULL (use the constants above for common values). Only the exact location specified by app-user-host is searched. The returned CFType must be released by the caller when it is finished with it. */ CF_EXPORT CFPropertyListRef CFPreferencesCopyValue(CFStringRef key, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); /* Convenience to fetch multiple keys at once. Keys in keysToFetch that are not present in the returned dictionary are not present in the domain. If keysToFetch is NULL, all keys are fetched. */ CF_EXPORT CFDictionaryRef CFPreferencesCopyMultiple(CFArrayRef keysToFetch, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); /* The primitive set function; all arguments except value must be non-NULL. If value is NULL, the given key is removed */ CF_EXPORT void CFPreferencesSetValue(CFStringRef key, CFPropertyListRef value, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); /* Convenience to set multiple values at once. Behavior is undefined if a key is in both keysToSet and keysToRemove */ CF_EXPORT void CFPreferencesSetMultiple(CFDictionaryRef keysToSet, CFArrayRef keysToRemove, CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); CF_EXPORT Boolean CFPreferencesSynchronize(CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); /* Constructs and returns the list of the name of all applications which have preferences in the scope of the given user and host. The returned value must be released by the caller; neither argument may be NULL. */ CF_EXPORT CFArrayRef CFPreferencesCopyApplicationList(CFStringRef userName, CFStringRef hostName) CF_DEPRECATED(10_0, 10_9, 2_0, 7_0); /* Constructs and returns the list of all keys set in the given location. The returned value must be released by the caller; all arguments must be non-NULL */ CF_EXPORT CFArrayRef CFPreferencesCopyKeyList(CFStringRef applicationID, CFStringRef userName, CFStringRef hostName); CF_EXTERN_C_END CF_IMPLICIT_BRIDGING_DISABLED #endif /*! __COREFOUNDATION_CFPREFERENCES__ */ // clang-format on The Hybrid Beetle Crown I made this guy as an experiment. My lovely Arum is modeling it. This Silver rhino beetle has 8 legs, assembled from 3 different beetle species. The articulated vertebrae tail is detachable. It actually belongs to another project of mine, but I attached it to the bug out of curiosity and loved the look of it. Because, why not? Eeee! I know we’re not supposed to use this word, but he looks so ‘COOOOOL’ on and off the doll! I love how his tail wraps around her neck in the 3rd pic. I think he’s kinda CUTE! – another no-no word?! >o< Well, if this was an experiment, it’s a fabulously successful one! Marina, your imaginative creations never cease to amaze me. The vertebrae tail is awesome. I’d really love to see the project that this was actually meant for as well! OMG, that is absoutely, divinely, stunningly amazing. I love bugs of any sort, but this is beyond wonderful. Sorry for gushing, but this is Seriously Fabulousâ™¥â™¥â™¥ Any chance of a large tarantula type spider? :) It’s incredibly beautiful! I think it’s my favourite headdress so far! I love how the beetle contrast with the more feminine and delicate curves of the piece. It reminds me a bit of Alexander McQueen’s aesthetic. Beautiful. Who would think a beetle could look so gorgeous and elegant and still very ‘bug-ish’ all at the same time? True art. I love it! I love all of the detail and sharp look about it (yes I thought of Alexander McQueen for a moment also). Thanks for the pictures! Your last 4 or 5 blog entries just appeared all at once. I thought maybe you were on vacation but they span almost a month. I checked the site once or twice a week during that time but their were no updates. Perhaps there was a problem with your site and that would explain why some people were worried about your absence. Regards. That is freaking stunning! Now, I wouldn’t want to run across that creature

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, Facebook will need to prove that it can transition Libra to a more permissionless model with actual decentralization. Currently, the criteria to be a validator is squarely in the hands of only 28 multi-national firms. The network is more comparable to a consensus model by corporate entities rather than anything remotely comparable to decentralization. More Cryptocurrency Exposure through Facebook Expected However, Lubin did identify some positive factors. For example, the Libra will inevitably expand the growth of users in the cryptocurrency space. It will also make financial payments much easier. With this in mind, “talented UX designers could reduce the friction of using cryptocurrency” Lubin said. “Managing private keys, understanding gas payments and installing crypto browser plugins could be as simple as pressing ‘send’ in WhatsApp.” The Libra is definitely not the end-all, but it could be a catalyst for actual decentralized solutions. Ultimately, it all comes down to trust. Facebook has made a poor attempt at remedying the public’s dislike of the social media giant in the wake of the Cambridge Analytica scandal. The fallout of that scandal has exposed the extent to which Facebook mines our data. With Libra, the social media giant will also be able to track our payment history. Therefore, Lubin is right to say that Facebook’s biggest problem today is trust. Hopefully, the Libra will merely bring visibility to the cryptocurrency industry rather than take over global payment systems. Do you believe Lubin’s assessment of the Libra is correct? Let us know your thoughts in the comments below.Surgical cutting or resection devices with drive units and rotating blades or burrs are commonplace in endoscopic surgery. Many current devices include a reusable drive unit and disposable rotating blades, burrs, or other attachments that are configured to couple to the reusable drive unit. During an endoscopic surgery, a surgeon may unknowingly apply forces to an instrument that have the potential of damaging the instrument or causing complications to the surgical procedure when using instruments of the previously existing designs. It would be advantageous to provide surgical instruments for endoscopic surgery that are capable of monitoring forces applied to the instruments. It may be further advantageous to have the capability to provide alerts of one or more types that notify a user when load limits that have been set for forces applied to the instruments have been reached. Some improved embodiments may include methods of calibrating a cutting tool with integrated force sensors to provide an alert when load limits are reached and methods of calculating loads applied to a cutting tool.Tag Archives: First day of school Today was the first day of the 2012-2013 school year. I dropped off Mary at the middle school gate, walked Jake to our local elementary school and into his new class, and since Emily is in high school I just gave her a firm kick out the front door. After my kids were tightly locked down into their three respective LA Unified schools, I came home, poured myself another cup of coffee and posted the following to my Facebook page: “It feels so weird to have the house to myself.” I hit “post” and then proceeded to read my friends’ News Feed for the morning. That’s when I realized I deserved the Worst Mother of the Year Award. Every single post of every single parent of a school-aged child had already uploaded a photo of their little angel’s first day of school. The kiddos were carrying Angry Bird lunch boxes and had Dora the Explorer backpacks over their shoulder blades and their spotless shoes were glittering and their shiny outfits were so new the tags were probably pulled off on the way to class. They were posing with old friends and new teachers, clutching siblings, and wiping the tears away from their sobbing parents. I, on the other hand, had completely forgotten about that precious Kodak moment. And now it was too late. It’s not like I could barge into my 16-year old’s French III class with my iPhone blazing. “Excusez-moi, Madam,” I could have said, and that would be the end of it since I don’t speak French. Then I’d take a quick snapshot of my daughter hiding under her desk. For the rest of her high school career, she would be known as That girl with the crazy paparazzi mom. I wouldn’t have been allowed to sneak into my 11-year old’s drama production class and loudly proclaim to her teacher that being the thespian that he is, he should understand why I must stop the class in their tracks from learning a Shakespeare sonnet or a David Mamet play or some improv demonstration where they all pretend to be caterpillars just so my daughter can be seen on the big screen (big depending on how large your computer monitor is). Normally I humiliate her just by breathing. This stunt would have pushed her so far over the edge that she probably have come home and tried to OD on gummy vitamins. And now that my baby boy is a big 1st grader, he’d be completely mortified if I popped into his new class and interrupted a lively reading of Junie B. Jones. “Stand over here next to Hendrix and say ‘cheese!’” Then I’d reposition him and shove another of his soon-to-be-former friends into the group. “Let’s do another one with Charlotte since you weren’t smiling.” Then he’d excuse himself to go to the little boys’ room and never come back. I could have had my first day of school Facebook photos. But alas, I missed my moment. So here’s my re-creation: I took it after my kids got home. Notice that Emily and Mary are already wearing their pajama bottoms. It’s too late to capture that first day of school moment. But at least I still have time to embarrass my kids. 718 S.E.2d 151 (2011) Correna C. HOWE v. Bradley Earl HOWE. No. 415P11. Supreme Court of North Carolina. October 6, 2011. Bradley E. Howe, for Howe, Bradley Earl. *152 Correna C. Howe, for Howe, Correna C. ORDER Upon consideration of the notice of appeal from the North Carolina Court of Appeals, filed by Defendant on the 23rd of September 2011 in this matter pursuant to G.S. 7A-30 (substantial constitutional question), the following order was entered and is hereby certified to the North Carolina Court of Appeals: the notice of appeal is "Dismissed ex mero motu by order of the Court in conference, this the 6th of October 2011." Upon consideration of the petition filed on the 23rd of September 2011 by Defendant in this matter for discretionary review of the decision of the North Carolina Court of Appeals pursuant to G.S. 7A-31, the following order was entered and is hereby certified to the North Carolina Court of Appeals: "Denied by order of the Court in conference, this the 6th of October 2011." Introduction {#S1} ============ The biological bases of obesity-related behaviors are poorly understood. Popular culture and the media perpetuate a 'headless, hungry and unhealthy' stereotype of the overweight individual as weak-willed, susceptible to the temptation of high calorie foods and prone to ill health^[@R1]^. However, it is unclear whether a common biological mechanism underlies predisposition to obesity as well as impulsive behavior and a preference for calorie-dense foods. This question is especially relevant in the context of aging as several adverse health outcomes are associated with obesity in the elderly ^[@R2]--[@R4]^. We report on the associations between the common obesity risk variant (rs1421085 single nucleotide polymorphism) in the fat mass- and obesity-associated gene, *FTO,* and longitudinal changes in adiposity, brain function, impulsivity and macronutrient intake in the Baltimore Longitudinal Study of Aging (BLSA)^[@R5]^. [Figure 1](#F1){ref-type="fig"} summarizes the study design. First, we examined whether *FTO* genotype influenced trajectories of body mass index (BMI) during aging. Second, using serial ^15^O-water positron emission tomography (PET), we compared longitudinal changes in regional resting-state cerebral blood flow (rCBF), an established marker of neuronal activity^[@R6]^, between obesity-related risk allele carriers (*FTO+*) and non-carriers (*FTO−*). Then, based on differences in the regional pattern of longitudinal changes in rCBF between *FTO* risk and non-risk groups, we asked whether *FTO* genotype influences longitudinal changes in impulsivity and dietary patterns during aging. Materials and Methods {#S2} ===================== Participants {#S3} ------------ The BLSA is a prospective cohort study of community dwelling volunteer participants in Baltimore, beginning in 1958, and is one of the largest and longest-running longitudinal studies of aging in the United States ^[@R5],\ [@R7]^. The community dwelling unpaid volunteer participants are predominantly white, of upper-middle socioeconomic status, and with an above average educational level. In general, at the time of entry into the study, participants had no physical and cognitive impairment (i.e. Mini-Mental State Examination (MMSE) score ≤ 24) and no chronic medical condition with the exception of well-controlled hypertension. Detailed examinations, including neuropsychological assessment and neurological, laboratory, and radiological evaluations, were conducted every 2 years. Written informed consent was obtained from participants at each visit, and the study was approved by the

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253, 27113, 273, 34159, 9600, 285, 3542, 8191, 7578, 369, 2797, 432, 512, 5014, 2720, 281, 253, 1263, 15, 187, 187, 11, 1672, 657, 6073, 11, 4679, 1712, 4538, 25, 94, 187, 22873, 187, 187, 1166, 5343, 1363, 313, 10722, 2363, 13, 9901, 1107, 28, 2363, 2491, 13, 5976, 283, 3141, 1107, 10, 342, 16529, 17451, 267, 12382, 313, 25, 9646, 3719, 285, 898, 9646, 6490, 10, 285, 247, 18258, 1979, 3687, 685, 884, 1186, 2188, 275, 9080, 497, 17692, 10804, 34373, 432, 29677, 48737, 10043, 13160, 2683, 552, 4675, 875, 5080, 4022, 285, 3978, 4240, 15, 12493, 1907, 29518, 13215, 390, 37085, 4918, 497, 417, 13410, 15, 380, 2644, 18258, 13, 25547, 48448, 342, 4618, 1980, 35845, 390, 278, 4740, 20755, 13, 369, 4845, 275, 247, 8781, 285, 4745, 25266, 13, 1293, 49632, 1971, 13, 327, 247, 495, 1186, 53, 3382, 14478, 25152, 313, 34, 2942, 6156, 19685, 13, 6778, 2824, 27147, 13, 9567, 13, 16333, 10, 970, 247, 2133, 18783, 323, 6447, 6322, 285, 247, 4567, 14, 10531, 815, 833, 3781, 11452, 18783, 323, 2625, 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could be reduced to 68% (46--72%) or to 28% (6--43%) of the original scan time compared to S/N^2^ Weighting and Equal Weighting respectively.Figure 5SNR as a function of the number of repeated acquisitions. The mean SNR obtained using AOC and S/N^2^ Weighting for PUFA spectra acquired from five patients is plotted as a function of the number of repeated acquisitions. Baseline SNR is also shown. The dotted line shows the maximum average baseline SNR (SNR = 10.4) and maximum average SNR using S/N^2^ Weighting (SNR = 14.1) after averaging for 256 acquisitions. To achieve the same SNR using AOC, the acquisition time can be reduced to 28% (6--43%) compared to baseline. If noise correlation is not ignored, the acquisition time can be reduced to 68% (46--72%) (1.5 times faster) compared to S/N^2^ Weighting. Values are given as median and range in parenthesis. Standard errors for each line are shown in Supplementary Fig. [S2a,b](#MOESM1){ref-type="media"}. Discussion {#Sec6} ========== In this work, we compared current algorithms for combining PUFA spectra acquired using MQC MRS on phased array coils in breast cancer. AOC yielded the highest SNR improvement in excised breast tumours, healthy volunteers and patients. Moreover, AOC showed robustness against voxels with relatively low baseline SNR and was not affected by the presence of contamination lipid signal. AOC can be used for breast tumours with wide range of volumes, PUFA, water or fat contents, demonstrating the applicability in clinical settings. AOC was the optimal algorithm consistently in both *ex vivo* and *in vivo* experiments. For *ex vivo* experiments, there was a clear difference in SNR improvement between the noise decorrelated algorithms (an average of 44% from AOC and nd-comb) and the linear algorithms (an average of 30% from S/N^2^ Weighting, S/N Weighting, and Signal Weighting). Among the linear algorithms, S/N^2^ Weighting had the best SNR improvement as predicted theoretically^[@CR9]^ followed by S/N Weighting and Signal Weighting as shown in brain MRS^[@CR9]^. WSVD gave a large variance of SNR improvement ranging from −100 to 77% dependent on the baseline SNR, since WSVD uses the PUFA spectra to estimate the weighting (reference spectra in AOC and nd-comb). A minimum baseline SNR (7.5 in this study) is required for WSVD to accurately identify the PUFA peak (phase and amplitude) in order to yield comparable SNR improvement as other noise decorrelated algorithms. This is in agreement with the literature findings in brain MRS where WSVD was shown to give comparable results with other noise decorrelated algorithms at high SNR levels but worse performance at low SNR^[@CR11]^. AOC gave significantly higher SNR improvement compared to nd-comb, because nd-comb eliminates correlated noise before linear combination while AOC balances the signal against the overall noise^[@CR10]^. For healthy volunteers, the difference in SNR improvement between the noise decorrelated algorithms and the linear algorithms was larger (up to 47%) due to higher noise correlation found *in vivo*. WSVD was susceptible to the presence of contamination lipid signal (for 4 out of 30 data), as found in brain MRS acquired near the skull^[@CR25]^ whilst comparable to AOC for data with no lipid contamination. In patients, the difference between noise decorrelated algorithms and the linear algorithms was 28%. WSVD was susceptible to the presence of contamination signal in two patients and the low baseline SNR in the remaining three patients. AOC gave significantly higher SNR improvement compared to each of the algorithms apart from nd-comb. However, caution should be practised in interpreting these findings due to the small sample size. Based on consistent results among the experiments, AOC is most likely to provide the maximal SNR improvement in patients without susceptibility to low baseline SNR or contamination signal. We examined the relationship between AOC and experimental conditions, including PUFA content, voxel volume and water/fat ratio. There was no dependency of AOC performance on voxel volume, and hence SNR level, in agreement with simulated and acquired MRS in the brain^[@CR11]^. There was also no dependency of AOC on PUFA content and water/fat ratio in tumour specimens nor on PUFA content in healthy volunteers. In contrast, WSVD showed dependency on baseline SNR as well as voxel volume, confirming the categorical difference shown in group analysis. Therefore, AOC is functional in a wide range of breast tumour sizes and PUFA, water or fat contents, making it the ideal choice for clinical applications. AOC, although independent from biochemical environment and voxel size in our study, is affected by voxel location^[@CR10]^. Voxels, centred on the tumour, were positioned at the isocentre in *ex vivo* experiments. However, positioning the voxels at the isocentre was not feasible for *in vivo* experiments, leading to a wider signal disparity across coil elements, and in turn to a more pronounced SNR improvement, as shown in brain MRS studies^[@CR9],[@CR10]^. The variability in SNR improvement observed *in vivo* was higher than *ex vivo* due to the varying voxel location across participants, and possibly the physiological differences across individuals. In patients, the variability in SNR and acquisition time improvement was additionally associated with the limited sample size of 5. Future studies will benefit from investigations on SNR and acquisition time improvement conducted on larger patient cohorts. Enhanced SNR can be used to improve the accuracy of PUFA quantification, trade for reduced acquisition time, or enhance acquisition voxel volume. In comparison to Equal Weighting, AOC reduces acquisition time to approximately a quarter (median: 28%, range: 6--43% of original acquisition time) to maintain same output SNR, or improves SNR by 61% (34--105%) with same scan duration (equivalent to a reduction of voxel volume to 62% or 85% in each dimension). We also compared AOC with S/N^2^ Weighting as a non-noise decorrelated algorithm yielding the highest SNR in our study among the rest of the linear algorithms. In that case, acquisition is 1.5 times faster (AOC reduces acquisition time to 68% (56--71%) compared to S/N^2^ Weighting) to maintain same output SNR, or SNR is improved by 24% (4--28%) with same scan duration. These results show that noise correlation in breast MRS should be considered to achieve an optimised combination. A fast acquisition would be clinically valuable for elderly patients, who might experience difficulties remaining still in prone position or maintaining shallow breathing. Furthermore, the enhanced SNR would allow the assessment of small tumours more prevalent in breast cancer following the introduction of screening programmes. Reduced scan time would also be valuable for PUFA MR spectroscopic imaging (MRSI) when assessment of the whole diseased breast is necessary^[@CR4]^. However, further analysis should be conducted to evaluate AOC performance on PUFA MRSI. This study was limited on a single scanner and future work will benefit from multi centre studies on larger patient cohorts using scanners from different vendors, magnetic field strength, and breast coils. However, we deployed different coils for data collection between *ex vivo* and *in vivo* experiments with the results demonstrating the applicability of the algorithms under diverse conditions. The tumours studied in this work were limited to invasive ductal carcinoma with large size, and future investigation should be carried out in smaller tumours and other phenotypes. However, invasive ductal carcinoma accounts for approximately 75% breast cancer cases^[@CR26]^, and the tumour size in this study is representative of typical patient population requiring MR scan. AOC, among current algorithms, provided the maximum SNR improvement and is robust against low SNR or contamination signal. The derived SNR improvement was not dependent on experimental conditions of PUFA, water and fat content or voxel volume. Hence AOC is the optimal algorithm for PUFA spectra acquired using MQC MRS in breast to improve quantification accuracy, reduce acquisition time and reduce acquisition voxel volume. Methods {#Sec7} ======= Experiments were conducted in freshly excised human breast tumours, healthy female volunteers and patients with breast cancer. The *ex vivo* and *in vivo* studies were approved by the North West -- Greater Manchester East Research Ethics Committee (REC reference: 16/NW/0032) and the North of Scotland Research Ethics Service (REC reference: 16/NS/0077) respectively. All experiments were conducted in accordance with the Declaration of Helsinki guidelines and written informed consent was obtained from all participants prior to the study. *Ex Vivo* experiments {#Sec8} --------------------- 17 female patients (mean age, 61 years; age range, 42--78 years) with invasive ductal carcinoma (8 grade II and 9 grade III) and a tumour size greater than 10 mm in diameter were enrolled consecutively from Aberdeen Royal Infirmary hospital between February 2016 and June 2017. Patients having undergone chemotherapy or hormonal therapy were not eligible. The whole tumour, freshly excised with wide local excision or mastectomy, was placed in a container and immediately scanned, without formalin treatment, on a 3 T clinical MRI scanner (Achieva TX, Philips Healthcare, Best, Netherlands) using a body coil for uniform transmission and a 32-element phased array receiver coil for signal detection. Whole excised tissues were positioned in the centre of receiver coil. PUFA data were acquired using a single voxel MQC PRESS sequence^[@CR4]^ with repetition time (TR) of 1250 ms, echo time (TE) of 130 ms, 1024 data points, spectral bandwidth of 2000 Hz, spectral editing frequency at 2.8

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; // LCA struct LCA { vector<int> e[MAXN]; int d[MAXN], p[MAXN][MAXM]; void dfs_(int v, int f) { p[v][0] = f; for (int i = 1; i < MAXM; ++i) { p[v][i] = p[p[v][i - 1]][i - 1]; } for (int i = 0; i < (int)e[v].size(); ++i) { int w = e[v][i]; if (w!= f) { d[w] = d[v] + 1; dfs_(w, v); } } } void init(int n, vector<int> e[MAXN]) { copy(e, e + n, this->e); d[0] = 0; dfs_(0, 0); } int up_(int v, int m) { for (int i = 0; i < MAXM; ++i) { if (m & (1 << i)) { v = p[v][i]; } } return v; } int lca(int a, int b) { if (d[a] > d[b]) { swap(a, b); } b = up_(b, d[b] - d[a]); if (a == b) { return a; } else { for (int i = MAXM - 1; i >= 0; --i) { if (p[a][i]!= p[b][i]) { a = p[a][i]; b = p[b][i]; } } return p[a][0]; } } } lca; vector<int> e[MAXN]; int stgcd(int a, int b) { int r = hld.r[a]; return st[r].gcd(hld.t[a] - hld.t[r], hld.t[b] - hld.t[r] + 1); } void stadd(int a, int b, int d) { int r = hld.r[a]; st[r].add(hld.t[a] - hld.t[r], hld.t[b] - hld.t[r] + 1, d); } int gao(int a, int b) { int ret = 0; // printf("gao(%d, %d)", a, b); while (true) { int c = hld.r[a] == hld.r[b]? b : hld.r[a]; // printf("[%d, %d] ==> [%d, %d]\n", c, a, hld.t[c], hld.t[a]); ret = ::gcd(ret, stgcd(c, a)); if (c == b) { break; } else { a = hld.p[c]; } } // printf(" = %d\n", ret); return ret; } void add(int a, int b, int d) { // printf("add(%d, %d, %d)\n", a, b, d); while (true) { int c = hld.r[a] == hld.r[b]? b : hld.r[a]; stadd(c, a, d); if (c == b) { break; } else { a = hld.p[c]; } } } int main() { int n, m, a, b, c, d; char op; scanf("%d", &n); for (int i = 1; i < n; ++i) { scanf("%d%d", &a, &b); e[a].push_back(b); e[b].push_back(a); } hld.init(n, e); lca.init(n, e); /* for (int i = 0; i < n; ++i) { printf("\t%d\t%d\t%d\n", i, hld.r[i], hld.t[i]); } */ for (int i = 0; i < n; ++i) { if (i == hld.r[i]) { st[i].init(hld.c[i].size()); } } for (int i = 0; i < n; ++i) { scanf("%d", &d); stadd(i, i, d); } scanf("%d", &m); for (int i = 0; i < m; ++i) { scanf(" %c%d%d", &op, &a, &b); c = lca.lca(a, b); // printf("LCA(%d, %d) = %d\n", a, b, c); if (op == 'F') { if (a == c) { printf("%d\n", gao(b, c)); } else if (b == c) { printf("%d\n", gao(a, c)); } else { printf("%d\n", ::gcd(gao(a, c), gao(b, c))); } } else { scanf("%d", &d); if (a == c) { add(b, c, d); } else if (b == c) { add(a, c, d); } else { add(a, c, d); add(b, c, d); stadd(c, c, -d); } } } return 0; } //Correct Answer //Execution Time: 17.80 di Mathias Hariyadi La facoltà di psicologia della Sanata Dharma (Usd) aveva indetto un incontro sul tema: “Lgbti: Siamo diversi, siamo unici e siamo Uno”. La sezione locale del Forum della società islamica ha imposto l’annullamento di un evento che “disonora l’islam”. Per un leader islamico i comportamenti sessuali “deviati” sono un “virus contagioso”. Jakarta (AsiaNews) - Dietro gravi minacce di estremisti islamici, l'università cattolica di Sanata Dharma (Usd) a Yogyakarta, nella provincia dello Java centrale, ha cancellato un seminario dedicato agli orientamenti sessuali "diversi", fra cui omosessualità, lesbismo, transgender. L'incontro, annullato in tutta fretta la scorsa notte, era stato promosso dalla facoltà di psicologia della Usd ed era previsto per il 27 settembre prossimo; tema del seminario "Lgbti: Siamo diversi, siamo unici e siamo Uno". Ieri il Forum della società islamica (Fui) ha annunciato che, in caso di mancata cancellazione dell'evento, avrebbe "infiltrato" propri elementi all'interno, per bloccare una discussione che avrebbe "disonorato l'islam". Johanes Eka Priyatna, rettore della Usd, conferma l'annullamento del seminario, al termine di un incontro a porte chiuse con i vertici della polizia, cui hanno partecipato anche docenti e membri del consiglio studentesco. Fra le città dell'Indonesia, Yogyakarta si è sempre distinta nel tempo per essere fra le più "tolleranti" e ospita dozzine di università di diversa ispirazione. Tuttavia, negli ultimi anni essa ha registrato episodi di intolleranza di natura confessionale, ad opera di gruppi estremisti musulmani locali che hanno preso di mira le comunità cattoliche e protestanti locali

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-AzureVM output after adding a datadisk](images/update-azurevm-output-after-adding-a-datadisk.png?raw=true) _Update-AzureVM output after adding a new datadisk_ <a name="install-vm-extension-powershell"></a> Now you will learn how to add extensions to the virtual machine just created. Microsoft Azure provides VM Extensions built by both Microsoft and trusted third-party providers to enable security, runtime, debugging, management, and other features you can take advantage of to increase your productivity with Azure Virtual Machines. For more details see [Azure VM Extensions and Features](https://msdn.microsoft.com/en-us/library/azure/dn606311.aspx). The **Azure Virtual Machine Agent** (VM Agent) is used to install, configure, manage and run **Azure Virtual Machine Extensions** (VM Extensions). The VM Agent is a secure, light-weight process that installs, configures, and removes VM extensions on instances of Azure Virtual Machines from the Image Gallery and on custom VM instances if they have the VM Agent installed. There are two Azure VM Agents, one for Windows VMs and one for Linux VMs. By default, the VM Agent is automatically installed when you create a VM from the Image Gallery, but you can also install the VM agent after the instance is created or install it in a custom VM image that you then upload yourself. You will now verify that the VM Agent is enabled in the virtual machine created in the previous steps, and after that install the Symantec Protection extension. Finally, you will verify that the extension was correctly installed on the virtual machine. All these steps will be carried out using PowerShell and using some of the same variables set previously. 1. To verify whether the VM Agent is enabled on the virtual machine, run these commands: ```PowerShell $vm = Get-AzureVM -ServiceName $cloudSvcName $vm.VM.ProvisionGuestAgent ``` The output of the first command should not return any errors, and the second command should be True. Running these commands will also set the $vm.VM variable, which will be used in upcoming steps to add the extension. >**Note:** If the value of the **$vm.VM.ProvisionGuestAgent** property is False, connect to the virtual machine and install the VM Agent. You can download it [here](<http://go.microsoft.com/fwlink/?LinkID=394789&clcid=0x409>). Then, set the value of the variable to True with the following snippets. > >```PowerShell >$vm = Get-AzureVM -serviceName $cloudSvcName -Name $vmname >$vm.VM.ProvisionGuestAgent = $TRUE >Update-AzureVM -Name $name -VM $vm.VM -ServiceName $cloudSvcName >``` Now you will install the Symantec endpoint protection extension. 1. Execute the following command to add the extension: ```PowerShell Set-AzureVMExtension -Publisher Symantec -ExtensionName SymantecEndpointProtection -VM $vm.VM -Version 12.* Update-AzureVM -ServiceName $cloudSvcName -Name $vmname -VM $vm.VM ``` **Set-AzureVMExtension** sets the properties for the extension about to be installed. **Update-AzureVM** is the cmdlet that installs the extension. The output of running all the commands up to now should look like this: ![Set-AzureVMExtension output](images/set-azurevmextension-output.png?raw=true) _Adding a VM Extension output_ 1. To verify that the extension was installed on the virtual machine, run the following command: ```PowerShell Get-AzureVMExtension -VM $vm.VM ``` The output of the command should look like this: ![Get-AzureVMExtension output](images/get-azurevmextension-output.png?raw=true) _Get-AzureVMExtension output_ <a name="connect-to-vm-powershell"></a> After you attach a disk to a virtual machine you need to initialize it so it's ready for use. To do so you will need to log in to the machine to finish the initialization of the new data disk attached. 1. Run the following command to create a remote desktop protocol file (rdp) and launch it. When prompted to log in, use the credentials for the administrator user you configured when creating the virtual machine. >**Note:** The location for the rdp file provided must exist, otherwise you will see an error. ```PowerShell Get-AzureRemoteDesktopFile -ServiceName $cloudSvcName -Name $vmname -LocalPath 'C:\myvmconnection.rdp' -Launch ``` This will launch the rdp, effectively starting the flow of connecting to the remote machine. ![Get-AzureRemoteDesktopFile output](images/get-azureremotedesktopfile-output.png?raw=true) _Get-AzureRemoteDesktopFile output_ 1. In the Remote Desktop Connection dialog box, click **Connect**. >**Note:**: You might need to wait until the virtual machine has booted for the rdp file to successfully connect and prompt for credentials. If so, retry by opening the rdp file from the location where it was saved until you are prompted for credentials. 1. Enter the user name and password for the Administrator user that was entered when creating the virtual machine (step 7) and click **OK**. ![Enter admin User credentials](images/enter-admin-user-credentials.png?raw=true) _Entering the admin user credentials_ 1. In the Remote Desktop Connection dialog box, click **Yes** to verify the identity of the remote computer. You can check "Don't ask me again for connections to this computer" if you do not want to see this dialog box again. ![Verify virtual machine identity](images/verify-virtual-machine-identity.png?raw=true) _Verifying the virtual machine identity_ 1. After a few seconds, the remote desktop window opens and starts setting up the session for the administrator user. Once it is finished, you will see the **Server Manager Dashboard** open, which you will use in the following steps to configure the data disk that you attached previously. For all other purposes, you could now work with this machine as you would with any other machine in your own environment. ![Using the remote virtual machine](images/using-the-remote-virtual-machine.png?raw=true) _Using the virtual machine_ <a name="configure-datadisk-powershell"></a> Now you will configure the data disk that you attached to the Virtual Machine. 1. In the **Server Manager Dashboard** that is open in the virtual machine, click **File and Storage Services**. ![Clicking File and Storage Services](images/click-file-and-storage-services.png?raw=true) _Clicking File and Storage Services_ 1. Once you are in the **Servers** pane of **File and Storage Services**, click **Disks**. ![Clicking Disks in File and Storage Services](images/clicking-disks-in-file-and-storage-services.png?raw=true) _Viewing the disks in File and Storage Services_ The disks available in the machine are listed. You will see one that is listed as Microsoft Virtual Disk, with the partition _Unknown_ and Capacity set to the size entered when the disk was created. 1. Right-click the disk and select **Initialize**. ![Initialize the disk](images/initialize-the-disk.png?raw=true) _Initializing the disk_ 1. Click **Yes** in the confirmation message box to confirm you want to continue erasing all data on the disk. ![Confirm initialization of disk](images/confirm-initialization-of-disk.png?raw=true) _Confirming initialization of the disk_ 1. After a short wait, the disk now has a Partition set. Right-click the disk and select **New Volume**. ![Creating new volume](images/creating-new-volume.png?raw=true) _Clicking New Volume in the context menu_ 1. Click **Next** in the **New Volume Wizard** dialog box that opens. 1. In the **Server and Disk** step of the **New Volume Wizard**, click **Next**. 1. In the **Size** step of the **New Volume Wizard**, update the volume size if desired and then click **Next**. ![New Volume Wizard - Size step](images/newvolumewizard-size-step.png?raw=true) _New Volume Wizard - Size step_ 1. In the **Drive Letter or Folder** step of the **New Volume Wizard**, update information as desired

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who looks at it and touches it, You do not allow any one to touch you in a way that you do not like.) Let us teach our sons, that rape is bad, and they have their responsibilities towards women. Cataract is the clouding of the lens in the eye that effects vision. Most cataracts are related to aging. Risk factors are diseases like diabetes, personal behavior such as smoking, alcohol use, and environmental factors like prolonged exposure to ultraviolet sunlight. According to the 3rd National Blindness Survey done in 2002, the top three causes of visual impairment are cataract, error of refraction, and glaucoma. Cataract is the number one cause of reversible blindness in the country. What are the symptoms of cataract? Cloudy or blurry vision Colors seem faded Glare. Headlights, lamps, or sunlight may appear too bright. A halo may appear around lights. Poor night vision Double vision or multiple images in one eye Frequent prescription changes in your eyeglasses or contact lenses. My mom was one of these Filipinos affected by cataract; she’s 73 years old and had undergone cataract operation with lens implant on both eyes a month ago. She was so fortunate to been under the care of an ophthalmologist, who is committed in providing the highest quality eye care to his patients. Her ophthalmologist, is diplomate eye specialist Dr Noel J. Lacsamana. Aside from his comprehensive treatment he provides to his patients, Dr Noel J. Lacsamana is on the forefront of disseminating information about eye health through several radio programs. Thank you Dr. Noel J. Lacsamana, for all your good deeds not just to my mom but for people from all walks of life, which you have cared for and treated. My mom can’t thank you enough for her better sight. You have definitely made a difference in the lives of many. Tang’s search for the future faces of Philippine film starts today. The theme for the first-ever KiddiCine Film Festival is “Because I Can”. Tang calls on children aged seven to ten years old to send in their short stories that will be the basis of their film. They can draw a picture, take a photo and write up the best, most inventive and most creative ideas to capture the attention of the Screening Committee who will be judging entries based on Creativity, Originality and Adherence to the Theme. Entries should be composed of a completed application form (with a short summary of the story) and an endorsement letter from the parents / guardian. All these have to be sent as “Tang KiddiCine Film Entry” to Ogilvy and Mather, Philippines, 25/F Picadilly Star Building, 4th Avenue corner 27th St, Fort Bonifacio Global City, Taguig City 1634 or you can also send entries online. For more information on contest requirements and to download the form, you may go online to www.facebook.com/tangkiddicine or search for Tang KiddiCine on www.facebook.com. Deadline is on October 28, 2010.Due to their favorable photophysical and spectral properties, complexes of lanthanide ions (particularly Terbium and Europium) offer significant advantages over organic fluorescent dyes. Compared with traditional organic fluorescent materials, the lanthanide coordination compounds have the following properties - long life-time, a large Stokes shift, and sharp fluorescent peak profiles. Due to these attractive properties, time-resolved reagents based on lanthanide fluorescence have been created. However, existing lanthanide products have not been fully successful in producing products with sufficient stability and brightness to compete with conventional organic fluorophores. Under this Phase I SBIR, Lumiphore will develop a Europium (Eu) fluorescent reporter based on the novel 1,2-HOPO sensitizing unit. The proposed reporter (Lumi4-Eu) will have exceptional photophysical and stability characteristics that will set a new benchmark for Eu reporters in a wide range of drug discovery, diagnostic, rapid sequencing and array applications. This research will result in a fluorescence reagent with exceptional stability, usability, and fluorescent properties that will expand the capabilities of time resolved fluorescent diagnostics by offering the second color of a duplex set of compatible, but complementary lanthanide reporters (the other being Lumiphore's terbium-based fluorescence reporter - Lumi4-Tb). Combining Lumi4- Eu and Lumi4-Tb will enable a new generation of time resolved fluorescence or time resolved Fvrster resonant energy transfer (TR-FRET) based multiplex applications. Lumiphore will use this technology to develop a rapid, multiplexed immunoassay diagnostic platform. This platform holds the promise of exquisite sensitivities, speed, and versatility for the increasing demands of 21st century healthcare. PUBLIC HEALTH RELEVANCE: The proposed research when combines with Lumiphore's existing terbium-based fluorescence reporter (Lumi4-Tb) will impact public health by enabling highly multiplexed diagnostic assay formats that combine fast turnaround times and high assay throughput efficiency. These assays will be used in high throughput screening (HTS) drug discovery, genomic screening, rapid DNA sequencing, clinical diagnostics and fluorescence microscopy applications for both basic and applied biomedical research.11.50am So, 38 overs each, three bowlers can bowl eight overs, two seven, and the third Powerplay is ditched. The pitch is bone dry, there's a breeze blowing across the ground... 11.45am Massive cheers as the last of the covers comes off, and the Sri lankans come onto the outfield to warm-up... again. "At least the raindrops have been musical," says a bored Andrew Miller. "The one dripping next to me fits the soca rhythm very nicely..." Now we are told a 12.15pm start and 38 overs a side. Believe it when it happens.Immunological competence and nutritional status in patients with lung cancer. The rate of infection in patients with malignant disease is significantly higher than in patients with benign disease. To investigate whether immunological competence is impaired in patients with lung cancer, we assessed neutrophil function (chemotaxis, phagocytosis, bacterial killing activity, and superoxide production), monocyte function (phagocytosis and killing activity), lymphocyte subsets using flow cytometry, and proliferation of lymphocytes stimulated by phytohemagglutinin, concanavalin A, and pokeweed mitogen. Studies were performed on 22 untreated patients with lung cancer and 21 age-matched healthy volunteers. Nutritional status was assessed by Niederman's nutritional index. In patients with lung cancer neutrophil chemotaxis, monocyte phagocytosis and killing, proliferation of lymphocytes stimulated by phytohemagglutinin and concanavalin A, but not pokeweed mitogen, and the number of natural killer cells were significantly lower than in healthy volunteers, whereas gammadelta T cells were increased (p < 0.05). The mean score on Niederman's nutritional index was worse in patients than in healthy volunteers (p < 0.001). Our results suggest that the impaired immunological competence and undernutrition may be among the mechanisms causing increased susceptibility to infection in patients with lung cancer.Wrzosy, Greater Poland Voivodeship Wrzosy is a village in the administrative district of Gmina Doruchów, within Ostrzeszów County, Greater Poland Voivodeship, in west-central Poland. It lies approximately east of Doruchów, east of Ostrzeszów, and south-east of the regional capital Poznań. References WrzosyPamela Anderson Talks Hugh Hefner & Sex Tapes in ELLE April 2014 She's had her fair share of scandals over the years, and now Pamela Anderson is ready to open up about her controversial lifestyle in the April 2014 issue of ELLE magazine. During her interview with the mag, the former "Baywatch" star dished about everything from first meeting adult entertainment mogul Hugh Hefner to her infamous sex tape. Check out a few highlights from Miss Anderson's Q&A session below. For more, be sure to visit ELLE! On Hugh: "I told Hugh Hefner, ‘I have this crazy boyfriend.’ And Hef was like, ‘You’re not going anywhere with a crazy boyfriend,’ and so he put me in a mansion in Bel-Air with an opera singing Chinese maid, and I was driving a Bentley, and a friend of mine came by and was like, ‘What is going on? Why are you living in this mansion?’ And I was like, ‘Isn’t this what happens when people move to LA?’" On her past relationships: "The rock-star thing became very destructive, like, wow. I didn’t know what I was doing. I just kind of became that thing. The hair, that rock-star kind of lifestyle, just living a dream. It kind of took over. It started out very innocent and then I turned into a cartoon character. And I started to feel like a cartoon character." On her children and the sex tape: "I don’t know if they’ve seen it, but they know about it. They know about everything. Stupid Internet. I don’t know why everyone is so impressed with it." On her pixie cut: "At first I thought I looked like Anderson Cooper or like a Q-tip or something. But now I feel really powerful. I have a friend who is an awesome, studly man, and he goes, ‘You know, some women cut their hair and it

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three months of life. These data showed a similar rate of growth between the CHD and control groups ([@bb0155]; [@bb0160]). However, 2D biometrics methods are global regional measures, as opposed to the analyses reported here, which reflect tissue-specific changes beginning prenatally at approximately seven weeks before our previous 2D neonatal measures. Additionally, 2D biometric measures have limitations in their correlation with 3D volumetry for tissue measures. For example, bifrontal diameter (2Dregional measure) and cortical gray matter volume (3D tissue-type measure) only have a correlation coefficient of 0.482 ([@bb0145]). Thus, this study expands our previous data by defining total and tissue volumetric changes from prenatal to postnatal imaging, which provides complementary information to our prior work regarding brain growth. 4.6. Limitations {#s0105} ---------------- This study has several limitations. First, the sample size is relatively small, which impacted the ability to define the relative contributions of specific tissue-types to longitudinal TBV, as well as the variance explained by relevant clinical factors. While exploratory analyses were undertaken, future studies with larger samples are needed to rigorously evaluate these relationships. Second, our sample includes a heterogeneous cohort of CHD that may have variable effects on brain development at different gestational ages, which could influence the timing and severity of fetal and infant impairments in brain development. Finally, our cohort had missing data at each MRI time point. We addressed this limitation with a random coefficients model, but there may be systematic differences between those subjects who did and did not undergo imaging at each time point. For example, infants deemed too unstable for pre- or post-operative MRI may have had the greatest deficits in volumetric measurements at this time point. Their findings might be better represented on the 3-month MRI results when these infants were more clinically stable and a larger number were able to undergo MRI scans. Despite these limitations, these data are the first to evaluate longitudinal changes in brain volume from prenatal to postnatal imaging and provide a foundation for future work investigating the timing of tissue-specific involvement in altered brain development. 5. Conclusions {#s0110} ============== This study demonstrated that infants with CHD have an altered trajectory of brain growth from fetal through neonatal and 3-month MRI. Importantly, by three months of age multiple tissue-types were involved, suggesting global disturbances in brain development that are likely multifactorial. The following is the supplementary data related to this article.Supplementary Fig. 1Longitudinal Imaging in Individual CHD Patients with and without Brain Injury. The top row represents the fetal MRI (A), neonatal MRI (B), and 3-month MRI (C) for Subject 5. The bottom row represents the fetal MRI (D), neonatal MRI (E), and 3-month MRI (F) for Subject 18. The white arrows demonstrate white matter injury, the white arrowhead demonstrates the left caudate infarct, the black arrows demonstrate bilateral intraventricular hemorrhage, and the black arrowhead demonstrates ventriculomegaly.Supplementary Fig. 1 This work was supported by the National Institutes of Health (NIH) Institute of Clinical and Translational Sciences (UL1 TR000448 and KL2 TR 000450) (C.O.), National Institute of Neurological Disorders and Stroke (K02 NS089852) (C.S.), National Institute of Biomedical Imaging and Bioengineering(R01EB018988) (A.G.), and the Eunice Kennedy Shriver National Institute Of Child Health & Human Developmentunder Award Number U54 HD087011 to the Intellectual and Developmental Disabilities Research Center at Washington University (B.L.S.); the Children\'s Discovery Institute of Washington University and St. Louis Children\'s Hospital (C.O. and C.S); the McKnight Foundation Technological Innovations in Neuroscience Award (A.G.); and a Career Development Award from the Office of Faculty Development at Boston Children\'s Hospital (A.G.). The content of this work is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors would like to thank Jennifer Brockmeyer and Reginald Lee for their assistance with recruitment and MRI analysis. [^1]: These authors contributed equally to this work. [^2]: Data are presented as mean (SD) or number (percentage), unless otherwise noted. Delivery and hospitalization characteristics are reported for 15 CHD subjects, as one subject transferred care to her local hospital prior to delivery. MRI characteristics were for those subjects with usable volumetric data. (−) Represents variables that were not applicable to the control population and could not be compared between groups. DM = diabetes mellitus, GA = gestational age, HTN = hypertension, PMA = postmenstrual age. [^3]: Data are displayed as median (interquartile range). [^4]: p \< 0.05. [^5]: AA = aortic atresia, AS = aortic stenosis, ASD = atrial septal defect, BT = Blalock-Taussig, DORV = double outlet right ventricle, d-TGA = dextro-transposition of the great arteries, HLHS = hypoplastic left heart syndrome, IVS = intact ventricular septum, L-TGA = levo-transposition of the great arteries, LV = left ventricle, MA = mitral atresia, MS = mitral stenosis, PA = pulmonary atresia, PDA = patent ductus arteriosus, RV = right ventricle, TOF = tetralogy of Fallot, TV = tricuspid valve, VSD = ventricular septal defect. [^6]: This subject transferred care back to her local hospital prior to delivery. [^7]: (−) Subjects unable to undergo MRI at that time point. BIS = brain injury severity, IVH = intraventricular hemorrhage, N/A = not applicable because perioperative MRI data not available, WMI = white matter injury. [^8]: MRIs with motion artifact precluding volumetric analysis. [^9]: Cardiac surgery was after the 3-month MRI for these subjects. [^10]: 3-month MRI was used for BIS score because cardiac surgery was 15 days prior to the 3-month MRI for this subject. [^11]: Preoperative atrial septostomy occurred in these subjects. Subject 18 had the septostomy before the preoperative MRI. [^12]: Data are displayed as the estimated mean (95% confidence interval) for the random coefficients model using the model estimates at the mean gestational age for each MRI time point. Mean gestational at fetal MRI was 32.7 weeks, at preoperative MRI was 39.7 weeks, and at 3-month MRI was 52.4 weeks. The percent difference is the difference in means relative to the control population. CER = cerebellum CGM = cortical gray matter, CSF = cerebrospinal fluid, SCGM = subcortical gray matter, TBV = total brain volume, WM = white matter. Lombardi: 'Able to stay in tune to the game' Michael Lombardi, the Browns’ new Vice President of Player Personnel, feels he benefitted from his experience with NFL Network. Michael Lombardi, the new vice president of player personnel for the Cleveland Browns, made his return to the NFL front office with Friday morning’s introduction after a five-year run with NFL Network and NFL.com. In working as an analyst for the NFL Network, Lombardi developed a unique perspective of the game that will help him in his new position with the Browns. “The great thing about NFL Network, and I’m really appreciative to them, is they afforded me an office at NFL Films, where I had the ability to watch football games and watch coach’s tape,” Lombardi said. “I was able to stay in tune to the game. Part of that, too, is to be able to have conversations with coaches all over the league about different teams, about their team. “It gives you perspective to look back, and any time you can take a step back from the game, look at it, adjust it, modify it, the NFL is about change every three years and you have to keep up with that change. It helped me (with) how we scout, how you look at things, how you want to do things over. I used to have a sign in my office with the Oakland Raiders that said, ‘If you don’t like change, you’re going to like irrelevance even less,’ by Eric Shinseki of the United States Army. I had that up for a lot of reasons, but I think change is really important.” In watching the game film, Lombardi, a former scout and player personnel director with the original Browns franchise, has seen a change in the NFL game. “The league, even five years ago, was a throwing league, but it’s become even more so,” Lombardi said. “The positions, the way you grade a draft board has to dramatically change because there’s so many more positions that you’re going to have to grade. It’s a broader spectrum, the requirements of the league. Remember, 10 years ago, there were a lot of teams running option football, pure option. Now, we’re in shotgun-option. The game’s changed dramatically.” Another change Lombardi

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1974); Hogan v. State, 572 S.W.2d 526 (Tex.Cr.App.1978). The convictions in Castillo, Hoaglund, and Weeks were affirmed in the absence of the statement of facts because those appellants failed to exercise due diligence in filing affidavits establishing indigency and the right to a free statement of facts. A comparison of those cases with the analysis adopted by the majority in Contreras and Mays suggests that, if the rule of diligence is applied to an indigent, the standard may differ from that articulated in Timmons as applicable to a non-indigent. The language of the Weeks opinion even states that, "it is incumbent upon a defendant to exercise due diligence to procure a transcription of the court reporter's notes by filing a pauper's oath." 521 S.W.2d at 862 [emphasis added]. The language of the statute makes no distinctions based on financial status, and certainly this court would not countenance an uneven application of the law. We conclude that the Timmons rule of diligence, a more recent decision than Weeks and supported by a long line of authority cited at 586 S.W.2d 512, is applicable to indigents and non-indigents alike. Accord: Wade v. State, 627 S.W.2d 777 (Tex.App.Waco 1981). In the instant case Appellant has demonstrated due diligence in establishing his indigency and requesting a statement of facts. The question remains whether the second prong of the rule of diligence articulated in Timmons is satisfied, i.e., has Appellant shown that the failure to file or have a statement of facts timely filed is not in any way due to negligence, laches, or other fault on the part of Appellant and his attorney? In our opinion a person of ordinary prudence would not delay 123 days after giving notice of appeal to contact the court reporter when the statute fixes responsibility upon the appellant to obtain the statement facts from the reporter and file it with the clerk not later than sixty days after notice of appeal. The record before us reflects no request for extension of time for filing the statement of facts. There is nothing in the record or even in Appellant's brief to suggest that counsel ascertained the identity of the court reporter or made any attempt whatsoever to contact the reporter prior to the expiration of the time for filing the statement of facts. In our opinion Appellant has not demonstrated that the unavailability of the requested statement of facts is not due to the negligence, laches, or other fault on the part of Appellant and his attorney. Therefore, Appellant is not entitled to reversal. In addition, we note that Appellant did not file with the clerk a designation of material for inclusion in the record but merely included in his affidavit of indigency a prayer for the court to direct the court reporter to *194 prepare a statement of facts. Tex.Code Crim.Pro.Ann. art. 40.09 § 2 (Vernon Supp. 1982) provides, in pertinent part, as follows: Each party may file with the clerk a written designation specifying matter for inclusion in the record. The appellant shall file his designation within 20 days after the giving notice of appeal.... The failure of the clerk to include designated matter will not be ground for complaint on appeal if the designation specifying such matter is not timely filed. [Emphasis added.] Furthermore, although the record lacks a statement of facts it reveals that Appellant entered a guilty plea and signed a stipulation of evidence establishing his guilt. When a plea of guilty is voluntarily and understandingly made, all non-jurisdictional defects including claimed deprivations of federal due process are waived. Helms v. State, 484 S.W.2d 925, 927 (Tex. Cr.App.1972); Galitz v. State, 617 S.W.2d 949, 952 (Tex.Cr.App.1981). We affirm. NOTES [1] Throughout this opinion we use the phrase "statement of facts" to mean a transcription of a court reporter's notes. In barber shops and beauty shops, customers often have their hair washed, dyed, curled, and provided with hair permanents, etc. as they lean backward in a chair with their neck resting on the edge of a sink. Typically, such a sink is of a special design having an indentation in its rim for receiving and supporting the neck of the customer. However, a hard sink rim can get quite uncomfortable for the customer over the long term as it presses against the neck and the back of the head, and can set off migraine headaches in some. By this invention a special pad is provided which greatly increases the comfort of the customer during treatment of the hair, while at the same time, the pad is very unlikely to slip out of its desired position in such an indentation of the sink rim.Q: Porting a MATLAB code to Python UPDATED TO REFLECT COMMENTS I am required to port a MATLAB code into python. Unfortunately, despite lot os sleepless nights of debugging and googling, I cannot get my code to run. Here is the MATLAB code in question: clc; serie =0:50; serie = serie - mean(serie); y = cumsum(serie); L = length(y); %Calculate the detrended fluctuation short term coefficient npuntos = 10; f1=zeros(1,npuntos); for n1=4:16 %Segmentation seg =(1:n1:L); %disp(length(seg)) yn = zeros(1,L); for k = 1:length(seg)-1 yaux = y(seg(k):seg(k+1)-1); x = 1:length(yaux); A=[sum(x.^2),sum(x); sum(x),length(x)]; C=[sum(x.*yaux);sum(yaux)]; v=inv(A)*C; a=v(1); b=v(2); pen=a; ord=b; ytrend = pen*x + ord; yn(seg(k):seg(k+1)-1) = ytrend'; end f1(n1) = sqrt((1/seg(end)).*sum((y(1:seg(end)-1)-yn(1:seg(end)-1)).^2)); end n1=4:16; f1=f1(4:end); p1 = polyfit(log10(n1(1:end-2)),log10(f1(1:end-2)),1); alpha1 = p1(1); disp(alpha1) My attempt to translate the code into python goes as follows: import numpy as np data = np.arange(start=0, stop=51, step=1) data = data.transpose() data = data - np.mean(data) y = np.cumsum(data) L = len(y) # Estimate the value of alpha1 npuntos = 12 f1 = [0] * npuntos for i, n1 in enumerate(np.arange(start=4, stop=16, step=1)): seg = np.arange(start=0, stop=L, step=n1) # Potential error yn = [0] * L for k in np.arange(start=0, stop=len(seg)-1, step=1): # Potential Error yaux = y[seg[k]:seg[k + 1]-1] # Potential Error x = np.arange(start=1, stop=len(yaux) + 1, step=1) A = [[sum(x ** 2), sum(x)], [sum(x), len(x)]] C = [[sum(x * yaux)], [sum(yaux)]] v = (np.linalg.inv(A)).dot(C) pen = v[0] ord = v[1] ytrend = pen * x + ord yn[seg[k]: seg[k + 1] - 1] = ytrend f1[i] = np.sqrt((1 / seg[-1]) * sum((y[1:seg[-1] - 1] - yn[1:seg[-1] - 1]) ** 2)) n1 =np.arange(start=4, stop=16, step=1) f1 = f1[4:] xx =np.log10(n1[1: - 2]) yy=np.log10(f1[1: - 2]) print(len(xx)) print(len(yy)) p1 = np.polyfit(xx, yy, 1) alpha1 = p1[1] print(alpha1) Unfortunately, I get TypeError when the program is executing this line p1 = np.polyfit(xx, yy, 1) This is indeed expected as xx is of length 9 while xx is just 5. By using try/catch block as suggested in the comment, try: f1[n1] = np.sqrt((1 / seg[-

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is the equal sharing of misery. - Sir Winston Churchill Americans love to fight. All real Americans love the sting of battle. - General George S. Patton Sr. The damage in that game is waaaaaay off. But it will get fixed. Unlike cod, the BF developers actually care what people think. +1. CoD developers just care about hacking. Battlefield has always been a top notch game, CoD is just good for a week then it gets boring. __________________ Socialism is a philosophy of failure, the creed of ignorance, and the gospel of envy, its inherent virtue is the equal sharing of misery. - Sir Winston Churchill Americans love to fight. All real Americans love the sting of battle. - General George S. Patton Sr. Here's my major issue, They shut down the beta because they threw a hussy fit over the feedback. Then they turn around and sell the beta for full price. I'm tired of hearing "it's a known issue and we are working on it". Here's my major issue, They shut down the beta because they threw a hussy fit over the feedback. Then they turn around and sell the beta for full price. I'm tired of hearing "it's a known issue and we are working on it".{% block page_product_detail_review_form %} {% if data is not defined and reviews.customerReview is defined %} {% set data = reviews.customerReview %} {% endif %} {% set formAjaxSubmitOptions = { replaceSelectors: '.js-review-container' } %} {% block page_product_detail_review_form_form %} <form class="review-form" action="{{ path('frontend.detail.review.save', { productId: reviews.productId }) }}" method="post" data-form-validation="true" data-form-ajax-submit="true" data-form-ajax-submit-options='{{ formAjaxSubmitOptions|json_encode }}'> {% block page_product_detail_review_form_csrf %} {{ sw_csrf('frontend.detail.review.save') }} {% endblock %} {% block page_product_detail_review_form_forward %} <input type="hidden" name="forwardTo" value="frontend.product.reviews"> <input type="hidden" name="parentId" value="{{ reviews.parentId }}"> <input type="hidden" name="forwardParameters" value='{"productId": "{{ reviews.product.id }}"}'> {% endblock %} {% if reviews.customerReview %} <input type="hidden" value="{{ reviews.customerReview.id }}" name="id"/> {% endif %} {% block page_product_detail_review_form_details %} <div class="form-row"> {% block page_product_detail_review_form_rating %} <div class="form-group col-md-4 product-detail-review-form-rating"> <label for="#review-form-rating"> {{ "detail.reviewFormRatingLabel"|trans|sw_sanitize }}{{ "general.required"|trans|sw_sanitize }} </label> <div id="review-form-rating" class="product-detail-review-form-rating-input" data-rating-system="true"> {% if data.get('points') is not empty %} {% set currentPoints = data.get('points')|number_format %} {% else %} {% set currentPoints = reviews.matrix.maxPoints %} {% endif %} {% set maxPoints = reviews.matrix.maxPoints %} {% for point in 1..maxPoints %} <label data-review-form-point="{{ point }}" class="product-detail-review-form-star{% if currentPoints >= point %} is-active{% endif %}"> <input class="product-detail-review-form-radio" type="radio" name="points" value="{{ point }}" {% if currentPoints >= point %} checked="checked"{% endif %}> {% sw_include '@Storefront/storefront/component/review/point.html.twig' with { type: 'blank' } %} </label> {% endfor %} {% for matrix in reviews.matrix.matrix %} <p class="h6 product-detail-review-form-rating-text {% if currentPoints!= matrix.points %} d-none{% endif %}" data-rating-text="{{ matrix.points }}"> {{ "detail.review#{matrix.points}PointRatingText"|trans|sw_sanitize }} </p> {% endfor %} </div> </div> {% endblock %} {% block page_product_detail_review_form_title %} <div class="form-group col-12 product-detail-review-form-title"> {% block page_product_detail_review_form_title_label %} <label class="form-label" for="reviewTitle"> {{ "detail.reviewFormTitleLabel"|trans|sw_sanitize }}{{ "general.required"|trans|sw_sanitize }} </label> {% endblock %} {% block page_product_detail_review_form_title_input %} <input type="text" class="form-control{% if formViolations.getViolations('/title') %} is-invalid{% endif %}" id="reviewTitle" placeholder="{{ "detail.reviewFormTitlePlaceholder"|trans|striptags }}{{ "general.required"|trans|striptags }}" name="title" value="{{ data.get('title') }}" required="required" minlength="5"> {% endblock %} {% block page_product_detail_review_form_title_violation %} {% if formViolations.getViolations('/title') is not empty %} {% sw_include '@Storefront/storefront/utilities/form-violation.html.twig' with { violationPath: '/title' } %} {% endif %} {% endblock %} </div> {% endblock %} </div> {% endblock %} {% block page_product_detail_review_form_content %} <div class="form-group product-detail-review-form-content"> {% block page_product_detail_review_form_content_label %} <label for="reviewContent"> {{ "detail.reviewFormContentLabel"|trans|sw_sanitize }}{{ "general.required"|trans|sw_sanitize }} </label> {% endblock %} {% block page_product_detail_review_form_content_textarea %} <textarea class="form-control{% if formViolations.getViolations('/content') %} is-invalid{% endif %}" id="reviewContent" name="content" required="required" minlength="40" rows="8">{% if data.get('content') is not empty %}{{ data.get('content') }}{% endif %}</textarea> {% endblock %} {% block page_product_detail_review_form_content_violation %} {% if formViolations.getViolations('/content') is not empty %} {% sw_include '@Storefront/storefront/utilities/form-violation.html.twig' with { violationPath: '/content' } %} {% endif %} {% endblock %} </div> {% endblock %} {% block page_product_detail_review_form_footer %} <div class="product-detail-review-form-footer"> {% block page_product_detail_review_form_required %} <p class="required-fields"> {{ "general.requiredFields"|trans|sw_sanitize }} </p> {% endblock %} <div class="product-detail-review-form-actions"> {% block page_product_detail_review_form_cancel %} <a href="#" class="btn btn-outline-secondary product-detail-review-cancel

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1340, 15, 1198, 436, 13, 359, 452, 908, 253, 6422, 2685, 5150, 2746, 534, 310, 247, 8967, 2715, 273, 10520, 457, 84, 39358, 1387, 9261, 15, 496, 9433, 436, 1332, 13, 359, 452, 2326, 326, 19124, 2426, 275, 253, 10520, 757, 3576, 26150, 313, 4609, 556, 247, 6486, 12160, 23046, 669, 2293, 45, 30, 46, 1366, 247, 8847, 4311, 9999, 5536, 14, 25268, 26682, 10, 403, 8171, 494, 407, 253, 3969, 2169, 15759, 8212, 9158, 5043, 4828, 27169, 323, 616, 3580, 275, 253, 19106, 2701, 313, 2811, 12160, 23046, 310, 6326, 281, 564, 281, 23579, 481, 380, 6158, 476, 320, 18445, 342, 342, 253, 1361, 273, 253, 2622, 1885, 4473, 15, 7243, 436, 958, 310, 8344, 13, 39401, 310, 15246, 27, 512, 370, 18, 16, 46, 768, 19, 47, 15728, 2621, 2538, 476, 320, 7011, 275, 2426, 273, 1980, 13388, 7668, 9158, 273, 7877, 3019, 21, 12, 19, 47, 3822, 1707, 1615, 359, 12666, 387, 247, 1980, 19106, 3576, 1673, 3762, 534, 8631, 1698, 14, 14115, 1708, 14, 25268, 12057, 13613, 598, 281, 667, 6799, 1340, 275, 370, 18, 16, 46, 63, 19, 5, 342, 4569, 10272, 4803, 323, 19124, 313, 4160, 445, 1939, 12729, 10, 13388, 15, 3932, 253, 7125, 1060, 403, 9093, 15759, 285, 8127, 3762, 14, 17777, 13, 352, 943, 417, 320, 2834, 281, 39970, 731, 281, 1027, 1673, 11813, 824, 347, 11206, 11813, 390, 11813, 342, 17046, 10377, 10155, 15, 8079, 13, 34430, 4906, 369, 8058, 323, 841, 11813, 275, 1008, 72, 343, 472, 6646, 62, 1561, 436, 2746, 15, 187, 187, 7542, 253, 27654, 323, 3576, 1980, 13388, 3831, 9136, 273, 669, 2808, 187, 9, 46, 16, 78, 1009, 275, 20452, 3762, 13, 352, 310, 2223, 11408, 281, 2020, 824, 21953, 334, 983, 275, 247, 12082, 1039, 15, 831, 556, 644, 6786, 407, 17617, 247, 873, 273, 5520, 9368, 266, 14, 23875, 11670, 1479, 7424, 1008, 2148, 70, 1570, 5220, 13, 1060, 359, 3710, 776, 4116, 281, 11302, 3470, 387, 10254, 2491, 669, 78, 30, 48, 9, 78, 3822, 1284, 581, 5459, 669, 78, 5, 281, 10481, 1029, 2341, 4311, 13, 253, 9722, 78, 16, 78, 16550, 39606, 359, 22459, 588, 2489, 1774, 15, 46769, 824, 669, 78, 2911, 39606, 285, 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&=&[S\_[int]{}\^[[[\_0]{}]{};N\_0-1]{}]{}+ \_i\[Ø\_i\^[(4+2N\_0)]{}\] +S\^[[[\_0]{}]{};N\_0]{}\_[CT]{}, where $a_i^{(4+2N)}$’s are appropriate linear combinations of $b_{2n,\{w\}}^{R;N}$’s (all of which are $O(1/M^{2N})$). Thus the $1/M^{2N}$-order information of the full theory is factorized into the coefficient $a_i^{(4+2N)}$’s of local vertices of dimension $(4+2N)$. If we want to increase the accuracy from $O(1/M^{2N_0})$ to $O(1/M^{2(N_0+1)})$, we have only to include in ${\widetilde S_{int}^{{{\Lambda_0}};N_0}}$ local vertices $[\O_i^{(4+2(N_0+1))}]$ of dimension $4+2(N_0+1)$. (The lower dimensional vertices need not be modified.) The coefficients $a_i^{4+2(N_0+1)}$ are calculable as the difference of appropriate Green functions of the full theory and those of the effective theory (i.e., ${\widetilde S_{int}^{{{\Lambda_0}};N_0}}$) at renormalization point. New divergences are subtracted away by $S^{{{\Lambda_0}};N_0+1}_{CT}$. Given this bare Lagrangian, the flow equation guarantees that all Green functions are finite and accurate up to order $1/M^{2(N_0+1)}$. The interpretation of this result is clear from the viewpoint of the renormalization group flow in the infinite dimensional space of possible Lagrangians. As we reduce the cutoff, the bare Lagrangian of the full theory, which is specified by the boundary conditions (\[fbc\]) and (\[fbc2\]), flows down to a submanifold parametrized by relevant couplings only. It has both heavy and light operators. Now the flow may be projected onto the subspace of operators consisting of the light field only. Then finding a local low-energy effective field theory of light particles is equivalent to finding a renormalization group flow with a few (relevant or irrelevant) local operators which can best approximate the projected flow of the full theory. To the zeroth order in $1/M^2$, it is done with relevant terms only by choosing the same renormalization conditions as those of the full theory. The deviation from the full-theory flow is corrected by reading off values of the remaining irrelevant coordinates at the $\LLL=0$ point. At first, components of dimension six operators may be read, which tell us the effects of order $1/M^2$; the flow of the full theory is now approximated to the order $1/M^2$ at $\LLL<M$. If one wants to increase the accuracy, it is necessary to read more and more irrelevant coordinates (at $\LLL=0$) of the projected flow of the full theory and modify the effective-theory flow with the corresponding flow equation given in Eq. (\[flowk\]). Our equation (\[flowk\]) automatically takes care of possible divergences due to the unnaturally large irrelevant components in such a way that the bare Lagrangian may contain only a finite number of irrelevant terms. Conclusions =========== In the context of a simple scalar field theory, we have demonstrated that, at low energy, virtual heavy particle effects on light-particle Green functions are completely factorized via effective local vertices to any desired order. For this, we have used the powerful flow equation approach which is a differential version of Wilson’s renormalization group transformation. In applying this method, we have seen that irrelevant terms in the Wilsonian effective Lagrangian (which has a finite UV cutoff $\LLL=M$, a characteristic scale representing heavy-particle thresholds) are replaceable by the corresponding higher dimensional composite operators plus counterterms for their products in the continuum limit (where UV cutoff is supposed to go to infinity). The latter can be dealt with with the help of the normal product concept. Once this fact is noticed, factorization is straightforward: all $1/M^{2N}$-order effects can be isolated in terms of local vertices involving operators of dimension $(4+2N)$. Thereby we arrive at a local continuum effective field theory which describes low-energy light-particle physics accurately up to any desired order in $1/M^2$ with appropriate calculation rules for irrelevant (nonrenormalizable) vertices. Since the arguments here are essentially dimensional and largely theory-independent, it should not be difficult to generalize them to different field theories such as gauge theories or theories with spontaneous symmetry breaking. Indeed, decoupling was proved for these theories in [@girardello] within this approach. Since the couplings for effective local vertices contain powers of $\log (M/m)$ in perturbation theory, it is often desirable to sum such logarithms in a systematic way. This has been achieved by utilizing a set of improved Callan-Symanzik equations [@clee]. Also, here we limited our attention to vertex functions at momentum range $\m=O(m)$. As one increases $\m$ to sufficiently high energy scale, the $(\m/m)$-dependence we neglected will become important. Keeping such $\m$-dependence and establishing bounds more carefully, one may study the high-momentum behavior of Green functions (even in the exceptional momentum region) within the effective field theory context. This bound has been obtained in [@ball2] for zeroth order effective theory (corresponding to decoupling). In summary, the flow equation, which is based on Wilsonian viewpoint of effective theory, provides clear understanding of effective theories in continuum. It is my great pleasure to thank Prof. D. P. Min for inviting me to the summer school. This work was supported in part by Korea Science and Engineering Foundation through SRC program. [99]{} K. G. Wilson, [Phys. Rev. [**[B4]{}**]{}]{} (1971) 3174, 3184; K. G. Wilson and J. Kogut, Phys. Rep. [**12**]{} (1974) 75. See, for example, K. G. Wilson, Rev. Mod. Phys. [**55**]{} (1983) 583. J. Polchinski, [Nucl. Phys. [**[B231]{}**]{}]{} (1984) 269. G. Keller, C. Kopper and M. Salmhofer, Helv. Phys. Acta [**65**]{} (1992) 32; G. Keller and C. Kopper, [Phys. Lett. [**[273]{}**]{}]{} (1991) 323. B. J. Warr, [Ann. Phys. (N. Y.) [**[183]{}**]{}]{} (1988) 1, 89. C. Becchi, in [*Elementary Particles, Field Theories and Statistical Mechanics*]{}, (M. Bonini, G. Marchesini and E. Onofri Eds) Parma University, 1993. Chanju Kim, [Ann. Phys. (N. Y.) [**[243]{}**]{}]{} (1995) 117 (hep-th/9402117). J. Berges, in this volume. C. Wieczerkowski, [Comm. Math. Phys. [**[120]{}**]{}]{} (1988) 148; G. Keller, Helv. Phys. Acta [**66**]{} (1993) 453. J. Hughes and J. Liu, [Nucl. Phys. [**[B161]{}**]{}]{} (1988) 183. G. Keller and C. Kopper, [Comm. Math. Phys. [**[148]{}**]{}]{} (1992) 445; [**153**]{} (1993) 245. R. D. Ball, P. E. Haagensen, J. I. Latorre, and E. Moreno, [Phys. Lett. [**[B347]{}**]{}]{} (1995) 80. T. R. Morris, hep-th/9802039 and referenced therein. M. Reuter and C. Wetterich, [Nucl. Phys. [**[B417]{}**]{}]{} (1994) 181 and references therein. U. Ellwanger [Phys. Lett. [**[B335]{}**]{}]{} (1994) 364. M. D’Attanasio and T. R. Morris, [Phys. Lett. [**[B378]{}**]{}]{} (1996) 213. C. Wetterich, [Phys. Lett. [**[B301]{}**]{}]{} (1993) 90. D. U. Jungickel and C. Wetterich, hep-ph/9710397 and references therein. T. E. Clark, B. Haeri and S. T. Love [Nucl. Phys. [**[B402]{}**]{}]{} (1993) 628. M. Bonini, M. D’Attanosio and G. Marchesini, [Nucl. Phys. [**[B409]{}**]{}]{} (1993) 441; [**B418**]{} (1994) 81; [Phys. Lett. [**[329]{}**]{}]{} (1994) 249. T. R. Morris, [Int. J. Mod. Phys. [**[A9]{}**]{}]{} (1994) 2411. F. J

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brown sugar, flour, and egg until blended. Press evenly into 15 by 10 by ¾-inch jelly-roll pan. Bake at 350 degrees for 15 minutes. For filling, sprinkle pecan halves evenly over crust. In large, heavy saucepan melt butter; add honey and brown sugar; stir to dissolve. Bring mixture to a boil over medium high heat and let boil for 5–7 minutes, or until mixture reaches a rich caramel color. Remove from heat and stir in whipping cream. Combine thoroughly. Pour caramel mixture over pecans. Bake at 350 degrees for 15 minutes, or until done; cool. **YIELDS 4 DOZEN BARS.** ### Almond-Fruit Diamonds _The "favorite cookie for 1980":_ Crust | ---|--- 3 C flour | 1 C sugar, divided 1/8 t salt | 2 eggs 1½ C butter, divided | ½ t grated lemon peel _**Topping**_ | ½ C honey | 1 C sliced almonds 2 T heavy cream | ¾ C red and green candied cherries 1 t vanilla | Preheat oven to 350 degrees. Adjust oven rack to lower third of oven. Grease 15½ by 10½-inch jelly-roll pan. Combine flour and salt in large bowl. Beat 1C butter and ½ C sugar in large mixing bowl at medium speed. Beat in eggs and lemon peel until mixture is light and fluffy. Gradually beat in dry ingredients. Press dough evenly into prepared pan, making a ¼-inch high rim. Bake 25–30 minutes until top is lightly brown and dough is firm to the touch. Five minutes before crust is done, melt remaining ½ C butter in saucepan, add honey, remaining ½ C sugar, cream, and vanilla. Heat to boiling, then boil, stirring for 5 minutes. Stir in almonds and fruit. Pour over crust. Bake 10 minutes more. Cool. Cut into 2 by 1¼-inch diamonds. **YIELDS 52 COOKIES.** _Source:_ Personal notebooks of Hermilda Listeman. ### Honey Lemon-Slice Cookie Bars 1 C brown sugar, firmly packed | 1 C pure honey ---|--- 2 C sifted flour | ¼ C lemon juice ½ C butter + 2 T | 3 eggs, beaten unmercifully 1 C shredded or flaked coconut | Blend together brown sugar, flour, butter, and coconut. Pat of mixture into an ungreased 9-inch square pan. In small saucepan, cook together honey, 2 T butter, lemon juice, and eggs, stirring constantly until mixture thickens. Cool and spread over coconut mixture in pan. Sprinkle remainder of coconut mixture over top. Bake at 350 degrees for 40 minutes. Cut in 1½-inch squares and cool in pan or rack. **YIELDS 3 DOZEN BARS.** _Source:_ Personal notebooks of Hermilda Listeman, with the note "from the Gourmet Co-op." ### Honey Nut Brownies _Note: If the brownies will be eaten immediately, use a combination of ½ C honey and ½ C brown sugar._ ¼ C butter | ½ C flour ---|--- 2 oz bitter chocolate | ½ t baking powder 1 C honey | 1 C chopped nuts 2 eggs, beaten | Melt butter and chocolate together, then stir in honey (see Note). Add eggs and stir to combine well. Sift flour and baking powder and stir into chocolate mixture. Add nuts. Bake at 300 degrees for 45 minutes. Pack brownies away in jar or bread box. Before serving, cut in strips about ½-inch wide and 2 inches long. Roll in powdered sugar if desired. _Source:_ Adapted from Vern Milum, University of Illinois Extension Service mimeographed bulletin, 1929. ### First-Prize Honey Date Bars _This recipe was a prizewinner at the 1934 Illinois State Fair Honey Culinary Competition. The recipes for that event were published without attribution and often (as in the case of this recipe) without instructions. A handwritten note on the recipe indicates that "second and third prizes were Kellogs [_ sic _] Honey Date Bars."_ 2 eggs | ¼ t salt ---|--- ¼ C honey | ½ T baking powder ¼ C sugar | 1¼ C dates, chopped C flour | ¾ C nuts, chopped Beat eggs well and mix in honey and sugar. Sift flour with salt and baking powder and add to egg mixture. Stir in dates and nuts. Spread in a greased 11 by 15-inch jelly-roll pan. Bake at 350 degrees for 15–25 minutes. Cut into strips ½ inch wide and 3 inches long. _Source:_ Adapted from the _Annual Report of the Illinois State Beekeepers Association_, 1934. ### Apricot Bars ½ C butter | 1 t salt ---|--- 1½ C brown sugar, packed | 1 t baking powder ½ C honey | 1 t cinnamon zest of 1 lemon | 6 oz dried apricots, chopped 3 eggs | 1 C chopped or slivered almonds 1¾ C flour | | _**Lemon Glaze**_ | | ¾ C powdered sugar | 1 T lemon juice Cream butter, sugar, honey, and lemon zest; beat in eggs. In a separate bowl, combine dry ingredients. Mix into creamed mixture and stir until thoroughly blended. Fold in almonds and apricots. Spread into 15 by 10 by 1-inch baking pan and bake at 350 degrees for 20–25 minutes. Cut into bars. To make the glaze, mix sifted powdered sugar with lemon juice. Pour over cooled bars. **YIELDS ABOUT 50 BARS.** ### Beehives _A recipe translated by Martin Hauser, a Ph.D. graduate in entomology at the University of Illinois at Urbana-Champaign and originally from Germany._ ½ C butter | 1 t cinnamon ---|--- 1 egg yolk | 8 T rose-hip jam 4 T honey | a few drops of lemon juice C sugar | 1 package agar-agar powder ½ C ground hazelnuts | powdered sugar for decoration 1 C flour | Mix butter, egg yolk, 1 T honey, sugar, nuts, flour, and cinnamon; refrigerate for 45 minutes. Roll dough flat (about ¼ inch thick) and cut 20 rounds approximately 1¾ inches in diameter, and 10 rounds a little more than an inch in diameter. Make hollow rings by cutting the centers out of all the small disks and 10 of the large disks. Place dough on baking paper. Bake at 350 degrees for 18 minutes. While dough is baking, mix the remaining honey, rose-hip jam, and lemon juice with the agar-agar powder. To assemble beehives, use a large disk for the bottom, and stack with rings. Fill the centers with the honey mixture; decorate with powdered sugar. **YIELDS APPROXIMATELY 10 BEEHIVES.** ### Really Rich Baklava _This recipe comes from Tugrul Giray, a University of Illinois at Urbana-Champaign bee biologist originally from Turkey and now living in Puerto Rico. As he describes it, "I had to first experiment and try this recipe at home. It is delicious! Definitely a diet food for gaining weight. I guess we can call it 'Baklava Heavy' or 'Non-light Baklava.'"_ _Note: Afyon cream (from Afyon Province, and reputed to be the most famous in Turkey, is prepared with water buffalo milk) will go on top of the baklava before serving. The first stage of this recipe needs to occur 36–48 hours before serving._ **_Topping_** | ---|--- 1 qt heavy cream | **_Syrup_** | ½ C orange blossom honey | 3 C water 2½ C sugar | 1 t lemon juice _**Filling**_ | 2–3 C walnut halves | ½ t cinnamon (optional) 1 T flavorful honey | **_Pastry_** | 1-lb package phyllo sheets | 1 stick butter (or more as needed) Simmer heavy cream in a wide container (a deep stainless-steel pan is preferable) on low heat, stirring more or less continuously for 1 hour. Pour the thickened heavy cream in a tray (about inch thick). Let cool to room temperature, cover with a layer of plastic wrap or waxed paper to prevent oxidation or color change, and refrigerate for 36–48 hours until it is solid and can be cut with a butter knife and served with a spatula. _To make the syrup:_ Mix orange blossom honey, sugar, and water; bring to a boil and let simmer for 30–40 minutes. Add lemon juice. Mix. Remove any foam or froth that may appear on the surface with a spoon or ladle. Leave this honey-sugar syrup to cool to room temperature on the kitchen counter. _To make the filling:_ Measure 2–3 C shelled walnut halves. Smash the walnuts to a granulate form

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data. To the best of our knowledge, the functions of these proteins have not been studied in eukaryotes. According to TargetP and MitoProt, CAS-like proteins in *K. brevis*(P = 0.763 and P = 0.870 respectively), *K. micrum*(P = 0.742 and P = 0.951), and a green alga *Ostreococcus tauri*(P = 0.748 and P = 0.706) are mitochondrial targeted. CAS-like proteins in *O. lucimarinus*and *Chlamydomonas reinhardtii*do not have an N-terminal extension. PSORT \[[@B50]\] predicts a peroxisomal localization for the fungal CAS-like proteins however, with low probability (P-value range = 0.500 -- 0.660). Phylogenetic analyses of the CAS-like proteins (Fig. [4](#F4){ref-type="fig"}) support the monophyly of the two chromalveolate lineages (BPml = 87%; BPnj = 87%; BPP = 0.99) and places chromalveolates in one clade with a cyanobacterium *Trichodesmium erythraeum*IMS101 (BPml = 100%; BPnj = 100%; BPP = 1.0). Most proteins of cyanobacterial origin were derived by chromalveolates from red or green algal progenitors of their plastids via secondary endosymbiosis \[[@B25],[@B26]\]. Absence of Plantae from the cyanobacterial-chromalveolate clade likely indicates that this cyanobacterial protein was acquired by chromalveolates not through endosymbiotic but rather through horizontal gene transfer. Recently, Waller at al. \[[@B15]\] reported another case of cyanobacterium-to-dinoflagellate HGT that involved a DNA fragment encoding the plastid targeted shikimate-O-methyltransferase junction protein. However, presence of the CAS-like proteins in haptophytes suggests a different scenario for the occurrence of this enzyme in dinoflagellates, which might include an additional, haptophyte-to-dinoflagellate HGT. Alternatively the CAS-like protein tree topology could be explained by the gene transfer from cyanobacteria before the divergence of chromalveolates and its subsequent loss from stramenopiles, ciliates, and apicomplexans. ![**Origin of clavaminic acid synthetase (CAS) -like protein in Chromalveolata**. ML tree of CAS and CAS-like proteins. The numbers above and below the branches are the results of ML and NJ bootstrap analyses, respectively. Only bootstrap values ≥ 60% are shown. The thick branches indicate ≥ 0.95 posterior probability from Bayesian inference. Branch lengths are proportional to the number of substitutions per site (see the scale bar). CH indicates chromalveolates. The name of the CAS protein-encoding gene that has been studied experimentally \[49\] is given in brackets. \* The position of *Alexandrium tamarense*within the haptophytes clade was inferred from the analysis of a short C-terminal sequence.](1471-2148-7-173-4){#F4} Energy metabolism ----------------- ### Iron-containing alcohol dehydrogenase and NAD-dependent aldehyde dehydrogenase Iron-containing alcohol dehydrogenase (Fe-ADH) and NAD-dependent aldehyde dehydrogenase (PutA) are probably the best-studied proteins from the perspective of HGT in eukaryotes. Aldehyde-alcohol dehydrogenase protein (AdhE) has arisen through the fusion of two protein domains, PutA and Fe-ADH and is considered to be a key enzyme in energy metabolism in parasitic amitochondriate protists \[[@B51]\]. Previous studies on parasitic protists demonstrated that AdhE-encoding genes have been subjects of multiple independent prokaryote-to-eukaryote HGTs. For information about AdhE functions and phylogeny in parasitic protists we would direct readers to references \[[@B51],[@B52]\]. In addition to previous findings, we identified Fe-ADH in free-living dinoflagellates and jakobids (see Additional file [1](#S1){ref-type="supplementary-material"}). These sequences share over 50% amino acid identity with bacterial homologs. Results of phylogenetic analyses suggest that the two lineages acquired Fe-ADH-encoding genes independently from closely related prokaryotes. The Fe-ADH tree obtained in this study is shown in Additional file [1](#S1){ref-type="supplementary-material"}. PutA has been found in free living dinoflagellates, stramenopiles, and jakobids (see Additional file [1](#S1){ref-type="supplementary-material"}). PutA sequences in these three lineages show over 50% amino acid identity to corresponding bacterial proteins and according to the result of phylogenetic analyses, originated through independent interdomain transfers from distinct prokaryotic donors (see Additional file [1](#S1){ref-type="supplementary-material"}). Phylogenetic analyses strongly support the monophyly of dinoflagellate and bacterial sequences (BPml = 100%; BPnj = 100%; BPP = 1.0) and suggest that dinoflagellates acquired PutA before the divergence of *Karenia*and *Karlodinium*. ### Malate-quinone oxidoreductase Malate-quinone oxidoreductase (MQO) is a functional analog of the better-known NAD-dependent malate dehydrogenase (MDH) that catalyses the conversion of malate to oxaloacetate in the tricarboxylic acid (TCA) cycle. In contrast to MDH, bacterial MQO is a membrane-associated enzyme that utilizes flavin adenine dinucleotide (FAD) as a cofactor and donates the electrons from malate oxidation to quinones instead of NAD \[[@B53]-[@B55]\]. MQO is protein common in bacteria. Among eukaryotes, this enzyme has been previously reported only for apicomplexans \[[@B56]\]. Apicomplexans lack the mitochondrial form of MDH. It has been shown that MQO compensates for mitochondrial MDH in the TCA cycle in this lineage \[[@B57]\]. We found two MQO-encoding genes in the *K. brevis*EST data. These share 60% amino acid sequence identity and about 44% identity with their bacterial homologs. Both have nucleotide compositions typical for *K. brevis*nuclear encoded genes (Table [2](#T2){ref-type="table"}). Using sequence similarity searches, we identified homologs of the *K. brevis*MQO in several species of dinoflagellates and haptophytes (see Additional file [1](#S1){ref-type="supplementary-material"}). Phylogenetic analyses support the monophyly of the two genes identified in *K. brevis*(BPml = 87%; BPP = 1.0) suggesting that they originated *via*gene duplication after the *Karenia*and *Karlodinium*divergence. Phylogenetic analyses place haptophytes and dinoflagellates within one clade (BPml = 84%; BPnj = 99%; Fig. [5A](#F5){ref-type="fig"}). The most parsimonious explanation for the observed MQO-DH tree topology is a haptophyte-to-dinoflagellate HGT that occurred early in dinoflagellate evolution. ![**Origins of two malate/quinone oxidoreductase (MQO) isoforms in Chromalveolata**. **A**. ML tree of MQO isoform DH. B. ML tree of MQO isoform A. The numbers above and below the branches are the results of ML and NJ bootstrap analyses, respectively. Only bootstrap values ≥ 60% are shown. The thick branches indicate ≥ 0.95 posterior probability from a Bayesian inference. Branch lengths are proportional to the number of substitutions per site (see scale bars). CH indicates chromalveolates. Only bacterial sequences that have a BLAST e-value ≤ 10^-20^to homologs in eukaryotes are included in these trees. Names of the MQO-encoding genes that have been studied experimentally \[54, 55, 57\] are given in brackets.](1471-2148-7-173-5){#F5} Surprisingly, comparison of the MQO sequences identified in dinoflagellates and haptophytes (MQO-DH) with the apicomplexan MQO (MQO-A) show that these proteins share significant similarity only at the short N-terminal FAD-binding domains (22% overall amino acid sequence identity). The analysis of the protein distribution and phylogeny showed that MQO-DH and MQO-A have been acquired by chromalveolates from different bacterial donors through independent transfer events (Figs. [5A, 5B](#F5){ref-type="fig"}). The fact that MQO-A shows highest similarity to homologs in epsilon proteobacteria (all BLAST hits with e-value ≤ 10^-20^) suggests that apicomplexans acquired MQO-A from this bacterial group. Homologs of MQO-DH have been identified in multiple bacterial lineages including firmicutes, actinobacteria, and three proteobacterial groups: alpha-, beta-, and gamma proteobacteria. Although the tree topology (Fig. [5A](#F5){ref-type="fig"}) does not allow us to identify the bacterial donor of the MQO-DH in chromalveolates, the presence of N

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slim and surprisingly small and light it is, I consider it to be a rather unique hybrid that combines qualities of both the Touch and the Nano. It’s very colorful and lovely OLED screen is slightly smaller than the touch screen, but the player itself feels quite a bit smaller and lighter. It weighs about 2/3 as much, and is noticeably smaller in width and height, while being just a hair thicker. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. Zune and iPod: Most people compare the Zune to the Touch, but after seeing how slim and surprisingly small and light it is, I consider it to be a rather unique hybrid that combines qualities of both the Touch and the Nano. It’s very colorful and lovely OLED screen is slightly smaller than the touch screen, but the player itself feels quite a bit smaller and lighter. It weighs about 2/3 as much, and is noticeably smaller in width and height, while being just a hair thicker. Between me and my husband we’ve owned more MP3 players over the years than I can count, including Sansas, iRivers, iPods (classic & touch), the Ibiza Rhapsody, etc. But, the last few years I’ve settled down to one line of players. Why? Because I was happy to discover how well-designed and fun to use the underappreciated (and widely mocked) Zunes are. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. Apple now has Rhapsody as an app, which is a great start, but it is currently hampered by the inability to store locally on your iPod, and has a dismal 64kbps bit rate. If this changes, then it will somewhat negate this advantage for the Zune, but the 10 songs per month will still be a big plus in Zune Pass’ favor. I’ll gear this review to 2 types of people: current Zune owners who are considering an upgrade, and people trying to decide between a Zune and an iPod. (There are other players worth considering out there, like the Sony Walkman X, but I hope this gives you enough info to make an informed decision of the Zune vs players other than the iPod line as well.) If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. Between me and my husband we’ve owned more MP3 players over the years than I can count, including Sansas, iRivers, iPods (classic & touch), the Ibiza Rhapsody, etc. But, the last few years I’ve settled down to one line of players. Why? Because I was happy to discover how well-designed and fun to use the underappreciated (and widely mocked) Zunes are. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. The new Zune browser is surprisingly good, but not as good as the iPod’s. It works well, but isn’t as fast as Safari, and has a clunkier interface. If you occasionally plan on using the web browser that’s not an issue, but if you’re planning to browse the web alot from your PMP then the iPod’s larger screen and better browser may be important. The new Zune browser is surprisingly good, but not as good as the iPod’s. It works well, but isn’t as fast as Safari, and has a clunkier interface. If you occasionally plan on using the web browser that’s not an issue, but if you’re planning to browse the web alot from your PMP then the iPod’s larger screen and better browser may be important. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. If you’re still on the fence: grab your favorite earphones, head down to a Best Buy and ask to plug them into a Zune then an iPod and see which one sounds better to you, and which interface makes you smile more. Then you’ll know which is right for you. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. The new Zune browser is surprisingly good, but not as good as the iPod’s. It works well, but isn’t as fast as Safari, and has a clunkier interface. If you occasionally plan on using the web browser that’s not an issue, but if you’re planning to browse the web alot from your PMP then the iPod’s larger screen and better browser may be important. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. Hands down, Apple’s app store wins by a mile. It’s a huge selection of all sorts of apps vs a rather sad selection of a handful for Zune. Microsoft has plans, especially in the realm of games, but I’m not sure I’d want to bet on the future if this aspect is important to you. The iPod is a much better choice in that case. The Zune concentrates on being a Portable Media Player. Not a web browser. Not a game machine. Maybe in the future it’ll do even better in those areas, but for now it’s a fantastic way to organize and listen to your music and videos, and is without peer in that regard. The iPod’s strengths are its web browsing and apps. If those sound more compelling, perhaps it is your best choice. The new Zune browser is surprisingly good, but not as good as the iPod’

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a base portion, 102 a cylindrical bearing holding portion provided substantially at a central portion on an upper surface of the base portion, 103 a bearing portion held in an inside of the bearing holding portion 102, 104 a thrust plate fittingly fixed in a lower opening of the bearing holding portion 102, 104a a thrust bearing sheet, 105 a stator, which will be described later on, made up of a stator core and coils and provided in such a manner as to surround circumferentially the bearing holding portion 102, 105a a stator core, 105b a coil wound around each of tees of the stator core 105a, 106 a circuit board affixed to the upper surface of the base portion 101, 107 a Hall element electrically connected and fixed to an upper surface of the circuit board 106, 108 a spindle rotatably supported on the bearing portion 103, 109 a turntable fixed to the spindle, 109a an annular yoke made to suspend vertically from an outer circumferential portion of the turntable 109, 110 an annular magnet provided on an inner side of the yoke portion 109a in such a manner as to oppositely face distal end portions of the tees of the stator core 105a, 111 a slip preventive material affixed near an outer circumferential portion of an upper surface of the turntable 109, 112 a disk holding portion provided at a central portion of the upper surface of the turntable 109 to hold a disk placed on the turntable 109, 113 a disk holding claw provided in such a manner as to move into and out of a sliding groove portion formed in such a manner as to extend from an outer circumferential portion of the disk holding portion 112 towards a central portion thereof, 114 a spring provided in an inside of the sliding groove portion so as to bias the disk holding claw 113 in such a manner as to protrude from the outer circumferential portion of the disk holding portion 112, 115 a hook locking portion formed an outer circumferential portion of an upper end portion of the bearing holding portion 102, and 116 a hook portion provided at a predetermined portion on a lower surface of the turntable 109 in such a manner as to be brought into engagement with the hook locking portion 115. In the conventional disk drive 100 that is configured as has been described above, a plurality of hook portions 116, which are formed by curving a metallic material, are provided around a circumference of the spindle 108, and the hook portions 116 are brought into engagement with the hook locking portion 115 on of the bearing holding portion 102 in such a state that the spindle 108 is securely inserted into the bearing portion 103, whereby the floating of the turntable 109 in association with the removal of an installed disk is prevented to thereby prevent the dislodgement of the spindle 108 from the bearing portion 103. In addition, the base portion 101 is formed by being punched from a relatively thick sheet metal so as to be imparted a predetermined mechanical strength because a load is exerted thereon when a disk is installed and removed. The stator core 105a is fixed to the bearing holding portion 102 at an inner circumferential portion thereof and is provided above the base portion 101 at a predetermined interval. In addition, an annular magnet 117 is adhesion fixed to an upper surface of the inner circumferential portion of the stator core 105a, so that the floating of the turntable 109 while rotating is prevented by virtue of a magnetic attraction force which attracts a lower surface of the turntable 109. In addition, the base portion 101 and the thrust plate 104 are strongly fixed to the bearing holding portion 102 by plastically deforming annular portions 102a, 102b which are provided on a lower surfaces of the bearing portion 102 through pressing. Additionally, a predetermined gap 118 is imparted between a lower portion of the disk holding claw 113 and the upper surface of the turntable 109. Next, a state will be described in which a disk is installed using FIGS. 16(a) to (d) which are sectional views of a main part of the conventional disk drive 100 showing a process of installation of a disk D. Here, FIG. 16(a) is a sectional view of a main part of the conventional disk drive which shows a state resulting before the installation of the disk D, FIG. 16(b) is a sectional view of the main part of the conventional disk drive which shows a state resulting at an initial stage of the installation of the disk D, FIG. 16(c) is a sectional view of the main part of the conventional disk drive which shows a state resulting at a middle stage of the installation of the disk D, and FIG. 16(d) is a sectional view of the main part of the conventional disk drive which shows a state resulting after the installation of the disk D, with the spring 114 omitted for the purpose of easing the understanding of the process. Firstly, as shown in FIG. 16(a), a gradient surface 113d which is inclined towards a radially outside of an upper surface portion 113c and a radially outside distal end portion 113b are formed on the disk holding claw 113. On the other hand, a sliding surface 112a which is inclined radially inwardly is provided on the disk holding portion 112 at a position which oppositely faces a distal end lower surface 113a of the disk holding claw 113. Next, as shown in FIG. 16(b), the disk holding claw 113 slides in a radially inward direction indicated by an arrow along the sliding surface 112a. Furthermore, as shown in FIG. 16(c), a sliding amount of the disk holding claw 113 becomes maximum in such a state that an inner circumferential wall of a center hole of the disk D coincides with the distal end portion 113b of the disk holding claw 113. Then, as shown in FIG. 16(d), while the disk D is brought into engagement at the center hole thereof when the disk is brought into abutment with an upper surface of the slip preventive material 111 and the disk holding claw 113 is biased by the spring 114 (not shown) so as to protrude, since the gap 118 is imparted, the disk holding claw 113 tilts about a fulcrum 112b, and therefore, there is produced a state in which the upper surface 113c of the disk holding claw 113 protrudes further upwards than an upper surface 112c of the disk holding portion 112. The gradient surface 113d which is inclined radially outwardly is provided on an upper surface on a radially outside of the disk holding claw 113 with a view to reducing a protruding amount which is a vertical distance between the upper surface 113c of the disk holding claw 113 and the upper surface 112 of the disk holding portion 112 as one of the purposes of the provision thereof. On the other hand, a spindle motor, in which a plurality of window portions are opened along a circumferential direction of a base plate at predetermined intervals, is disclosed in (P JP-A-5-38115) as a conventional spindle motor that is used as a drive portion of the conventional disk drive. According to Patent Document No. 2, an axial length can be reduced by allowing part of each winding portion of a stator to enter the window portion, thereby making it possible to realize the thinning of the disk drive as a whole. Note that the stator is fixed to the base plate in such a state that an annular main body portion and distal end portions of tees of a stator core are brought into abutment with circumferential edge portions of the window portions. However, the conventional techniques have had the following problems. (1) In the conventional general disk drives, since the turntable is made by drawing or cutting a sheet metal, there have been caused problems that the weight of the turntable so made is increased, and when the thickness of the turntable is attempted to be reduced with a view to reducing the weight and thickness thereof, the strength of the turntable is decreased, and that a complex and trouble some working is required for a center portion thereof where a spindle is to be fixed. (2) In addition, since it is a general practice to form the turntable into a flat shape by drawing or cutting a sheet metal, there has been caused a problem that an unnecessary space is produced between a lower surface of the turntable and the bearing portion and the bearing holding portion, and hence the overall thickness of the disk drive becomes thick, making it difficult to make the disk drive thinner. (3) Since the hook portions 116 is made up of a separate member from the turntable 109, there have been caused problems that the number of component is increased and that the number of manufacturing manhours required for a press bonding or welding process of fixing the hook portion 16 to the lower surface of the turntable 109 is increased, and additionally, since when attempting to thin the disk drive 100, a vertical length of the hook portion 116 is reduced, there has been caused a problem that a sufficient flexibility cannot be imparted to the hook portion 116, thereby making it difficult to mount the hook portion on the turntable 109. (4) Since the disk holding claw 113 is not only pushed to a center side of the disk holding portion 112 but also slides downwards when the disk D is installed, there has been caused a problem that the predetermined gap 118 becomes necessary on the upper surface side of the turntable 119 for allowing the disk holding claw 113 to slide downwards, this increasing the overall thickness of the disk drive. (5) In addition, since a punched sheet metal is used as the base portion 101, there have been caused problems that not only the thickness but also the weight of the disk drive is increased, thereby making it difficult to reduce the weight and thickness of the disk drive and that when attempting to reduce the thickness, the mechanical strength thereof is reduced. In particular, since a large magnitude of external force is exerted on the base portion 101 via the spindle 108 and the bearing portion 103 when the disk D is installed and removed, a predetermined strength is required. Note that as with the spindle motor in (Patent Document No. 2),

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–98 Cambridge Declaration on Consciousness, 239 Carhart-Harris, Robin, 214–15, 217, 230 Case, Laura, 194 _C. elegans,_ 65–66, 66n, 238–39, 254–55 Center for Gender Sanity, 192 Central Intelligence Agency (CIA), 221–22 central nervous system, 62, 120. _See also_ neurons (nerve cells) _The_ _Cerebral Cortex of Man_ (Penfield), 57 Chalfie, Martin, 66 Chandler, Arthur, 220–21 Chandler, Raymond, 107 Châtelet, Émilie du, 168 Cheap Date gene, 108–9, 109n, 112, 134 Chemero, Anthony, 159–61 Child, Julia, 33 Childhood Gender Nonconformity (CGN), 195 chimerism, 36–37 Chivers, Meredith, 172, 179, 180, 181–82, 196, 197 chromosomes, 25, 26–27 Churchland, Patricia, 237–39, 242, 245, 248, 249, 255–56 Churchland, Paul, 237 claustrum, 241 Clendinen, Dudley, 260 cluster headaches, 225–26 cognitive dissonance, 194, 278 Colbert, Stephen, 174 Coleman, Sidney, 232 Coleman, Todd, 163–64 comas, 54, 242–43, 244 _Confessions of an English Opium Eater_ (De Quincey), 122–23 connectome, 63–68, 165, 280 "conscientiousness" personality factor, 90, 142, 142n, 146, 154, 244–45, 258 consciousness, 141, 235–39, 240–46, 246–50, 250–56, 256–59 Controlled Substances Act, 223 Cool, Nadean, 276 Cooper, Anthony Ashley, 246 core self, 269–70 corpus callosum, 176–77, 277 Cowan, Jack, 217, 219 Crick, Francis, 16, 24, 26, 214, 214n, 241, 255 Csikszentmihalyi, Mihaly, 144–45 cues, 141, 155 _The_ _Cult of Personality Testing_ (Paul), 86 culture, 83, 182, 188–89, 197, 222 cytosine, 25, 27 Daisey, Mike, 278–80 Dalí, Salvador, 215 Damasio, Antonio, 244, 245 death, 231–32, 235–36, 256, 258–59 default mode network, 58–59, 215 delayed gratification, 125–26, 127 delerium tremens (DTs), 109, 111 Delysid, 220 dementia, 256–57 Denk, Winfried, 65 depression, 91, 97–104, 123, 124, 220, 231 De Quincey, Thomas, 122–23, 129 Descartes, René, 240–41, 245 _Diagnostic and Statistical Manual of Mental Disorders_ (DSM), 189, 190n Dick, Danielle, 119–20, 129, 132–33 "dissembling," 69 DMT (dimethyltryptamine), 206, 225 DNA (deoxyribonucleic acid), 13–16, 16–17, 24, 25, 27–28, 99, 214. _See also_ genes and genetics Doblin, Rick, 224–25 _Doors of Perception_ (Huxley), 214 dopamine, 63, 101–2, 104, 121, 134n, 225 Drake, Betsy, 220 Duffin, Shari, 43 Eagleman, David, 46, 242 earwax, 6, 28 Ecstasy, 206, 230 Educational Testing Service, 81 ego, 207, 209, 212–13, 215, 221 Ehrsson, Henrik, 161–62 _The_ _Electric Kool-Aid Acid Test_ (Wolfe), 207 emergent phenomena, 244–45, 245n, 258 Emma (transgendered person), 185, 192 Engel, Andreas, 250 Entheogen Corporation, 226 environmental influences and alcoholism, 124, 132 and brain physiology, 54, 64–65 and gender identity, 188–89 and individualism, 76, 83, 92, 96 interaction with genetics, 6–8, 28, 30, 42 _See also_ culture epidermal growth factor (EFG), 112 epilepsy, 56, 74n, 247, 277 "episodic future thought," 274–75 ergot and ergotism, 206, 210–11 Ermentrout, Bard, 217 _Essay Concerning Human Understanding_ (Locke), 246 estrogen, 199 ethanol, 107–11, 111–16. _See also_ alcohol and alcoholism evolution, 30–31, 69 existential fear, 231–32 extrastriate body, 58 extroversion, 78–79, 84, 90, 102, 146, 154–56 eyes, 34–37, 216–17 eyewitness testimony, 280 Facebook, 145–48 facial recognition, 56–59 failed relationships, 77–80 Fairchild, Lydia, 36–37 false memories, 275–78 family histories, 111, 124 Fausto-Sterling, Anne, 186–87, 191 Featherstone, David, 175 Federal Bureau of Investigation (FBI), 223 "feeling" (personality dimension), 79, 81, 83–84 feeling regulators, 141–42, 142–43 Ferguson, Craig, 129–30, 134, 229–30 fetal development, 177, 178, 185 Feynman, Richard, 214 fight-or-flight response, 272 Fisher, Helen, 76 flashbacks, 222, 224 "flashbulb memories," 273 fMRI (functional magnetic resonance imaging), 47–48, 50, 55, 58, 68–71, 101–2, 131, 140, 214, 263 Foerster, Otfrid, 56 Forer effect, 85–86 Forster, E. M., 280 Fowler, Lorenzo, 52 Fowler, Orson, 52 Fox, Arthur L., 31 Franklin, Rosalind, 24 fraternal twins. _See_ twins Freud, Sigmund, 78–80 frontal lobes, 98, 128, 132n fruit flies ( _Drosophila melanogaster_ ), 107–11, 111–16, 175 Future Oriented persons, 126–27 Gage, Phineas, 53–54, 56, 66–67 Galen, 74n Gall, Francis, 51–55, 53 Gallant, Jack, 70–71 Galton, Francis, 4–5, 88, 170 gamma-aminobutyric acid (GABA), 63, 120, 133 Gates, Bill, 214 Gazzaniga, Michael, 277–78 gender and alcoholism research, 120–21 gender atypical behaviors, 167–72 gender expression, 195–201 gender identity, 189–94 online avatars, 153 personality traits, 83 self-representation, 155–56 sexual behavior in the natural world, 172–78 sexual orientation, 179–83 transgendered identity, 183–88 Gender and Family Project, 169 generative people, 268–69 genes and genetics and alcohol tolerance, 107–11, 111–16, 116n, 132–33, 134n and anxiety, 98–99 and Big 5 personality traits, 96–97 and depression, 99 and determinism, 6 and DNA, 25–27 and eye color, 34–37 and gender identity, 188 genome mapping and sequencing, 14, 16–17, 18, 20n, 64, 67, 110, 214 genotypes, 17, 39 and impulsivity, 128 incompletely dominant genes, 20n and Miescher's work, 24–25 and personality, 97–104 privatization of, 42n and risk factors, 39–40 and sexual orientation, 175–76 and transgendered identity, 185 and variation, 23–24, 28–29 Gerber, Andrew, 262, 269–70 Gil da Costa, Ricardo, 55, 59, 68

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Including the Bruce! Your aim, our aim, was to capture him, and you failed! My scouts are searching for him, Your Highness. And a reward has been offered. It will be your head if he's not found. - Lord Buchan. - Your Highness. You bring news of the Bruce? No, Your Highness, his wife and child. Marjorie, we've been riding horses for days. Are you not tired yet? No. English soldiers approaching, we have to go now. Get to the trees, I'll send horses and men. Go. Lord Fraser! We know you have the Bruces wife and child. Hand them over and I spare the castle! Draw! They are not here, Your Royal Highness. Loose! Theres no need to burn us down. I will open the gate. Neil, where's Robert? Your Highness, I dont know. Where are his wife and daughter? They left for Turnberry on Tuesday. They left for Turnberry on Tuesday? Ow! Elizabeth! Where is your brother? I swear I don't know. I swear I don't know! - Uncle Neil! - I swear! - You forced my hand, Neil. - Elizabeth! - I swear! - Let him go! - I swear I don't know! - What are they doing? - No, please. I swear. - Uncle Neil! No! No! Look at me! No, no! No! No! Stop! No, Neil! Where is your husband? We dont know. We dont know. Please, have mercy. Your father is a tyrant, you are not. You think me weak? Compassion is not weakness. I have all the traits my father has, save one: mercy. Fraser. You seem like a... reasonable man. Where's the Bruce? I truly dont know. Hang them both up for all to see what becomesof those who support the outlaw Bruce. Take the women to England, seize all his lands. Leave him with nothing. See you later. Come on. Lord Mackinnon. I heard a rumor you made yourself king, and the Prince is tearing Scotland apart looking for you. I've come to ask for your support. My men and I stood with Wallace at Falkirk. Where were you then? There was no winning Falkirk. You know that. How can I follow a man who's never won an open battle? From what I've been told, you barely escaped Methven alive. We were ambushed in the dead of night. How many men have you? Forty. I'm still rounding people up. I wish you luck. I truly do. Come on, Lachlan! I've known you for over 25 years. - Now just please, give us some people... - Angus! - We've come here for your help. - Are you done? I believe, in time, you'll change your mind. And I'll be waiting. Move. Good to see you all again! Hamish, how you doing? How you doing, boy? My darling! Where the fuck have you been? You said three weeks, its been four months! Much has happened, my love. Oh, Angus. - Maybe I'll see you later, then. - Sure. Is that Robert? Our new king. Aye. Welcome, Your Majesty. It's good to see you again, Aine. Come! Lets get you warm and fed. One man to down the horse. And one man to remove the knight. And then to kill him. Weak spots under the arm, the neck... On your feet. And in the groin. You go near my daughter again, I'll cut them off and use them as bait. Are we clear? What you doing, you bastard? - I'll kick your bloody arse, Douglas, eh? - You taste sweeter! You think that's bloody funny? Right. Who's next? Thank goodness. I'm to take the girl to our convent for religious training. Only the girl. Oh. Isn't that wonderful? The sisters want to look after you. And they are gonna take such good care of you. Come, child. Are you coming? No. No, but... we'll all be home again soon. I'm certain of it. And Father? Mm-hmm. Come on. Come here. - No. - Come on, Marjorie. Please, don't make this hard. No, I don't want to go! No! Marjorie, I'll see you soon. I promise. I love you. - No, I want to go back! - I love you. - You'll be fine. - Let go! No. Elizabeth! Let go of me! Elizabeth! Your Grace. Angus's other daughter. Oh, here he comes. This could get interesting. Kildrummys fallen. Every man massacred. Your brother was hanged, drawn and quartered. My wife? My daughter? Theyre both alive. Taken by the Prince. We have to go back. You wanted to be king. Well, you're king now. This is the price you pay. We only win if you survive. Thinking about revenge? I know the feeling. It tears at the soul. But it can also be a weapon. No more chivalry. Now we fight like wolves. Open the gate. - You know him? - Aye. Come on, James. Whoa! Whoa, whoa, whoa! Lord Bruce. Your Majesty. Your Majesty. Iain. Youre late. Where have you been? Aye, sorry. Wheel came clean off. Took an age to fix it. Yeah, well, come on! Lets unload this before they gut the both of us. By the gate! What've you got in there? - Porridge. - Oh... I'll have some of that, then. Come on, get me a bowl. Of course. Come on! Follow me! Die, you bastard! To the stairs! Follow me! Arm yourselves!Arm yourselves! Seamus. Are you all right? Your Majesty! Its good to have you home. We cant stay. Theyll know where we are. - Youre all to come with us. - Aye. We take what we can, and burn it down. - Gayle! - Leave nothing for the enemy. Burn it! Burn it all! This is how we do it. We travel in stealth. Strike without warning. Take the land back castle by castle, destroying them as we go. Its not exactly chivalry, but I like it. Burn it all and take what you can! Let's move! Robert, you know, my fathers land is only a days ride. It would mean so much to me if I could take it myself. You know, Id only need two or three men. Take five. And keep your wits about you. I've already lost two brothers, I can't bear to lose another. Everyone out! Good luck, boy. Palm Sunday... Alleluia! Alleluia! Douglas! Douglas! I watched once, from that very window, my mother and father standing in this courtyard. And my father whispering in my mothers ear. I dont know what he said, but it must have been funny because she... she couldnt stop laughing. I used to drink this water. Poison it. Throw the bastards down the well. Wheres that cunt Clifford? Hes gone to join Valence, my lord. Well, then, Ill see him soon enough. Friends, don't be afraid. Please join me. No! Come, enjoy this Palm Sunday feast. It was prepared for your enemies. It is yours now. As is everything in my familys castle. I serve Robert Bruce, King of Scots! Join us to free our land! Sir Richard's castle in Scotland has also fallen. The man responsible may have been mad. He was heard screaming the same word over and over. Douglas. He claimed to be fighting for Robert the Bruce. The outlaws continue to sack their own castles, and as word of Bruce's exploits spreads, so does his support amongst the people. Of course, there are still nobles who remain loyal to the Crown. This morning... I woke up... performed my ablutions, and then walked from my bedchamber to the great hall. And on the way, I stumbled. No reason, just... just lost my footing. Well, I lose my footing sometimes. Especially in the morning when the body is still waking up. It was my hope to grow old and not die on the battlefield. But I see now that the great danger in a deathfrom natural causes is that one may be lying in one's bedchamber, thinking of all the things that have been left undone. Fear not, Father. We will not fail you again. Well, you managed to imprison a few women. These gentlemen of France were in the dungeon. They wish to join us. Is it true? Youre the King of Scots? He certainly is, you cheeky wee shite. Hey. Go tell all your friends were going to win our country back. Aye, Sire. Come on, Arthur. Is that really the King? Robert.I bring more men. - Drew! - Your Majesty. - Good to have you back! - We found them on the road. We thought you were dead! They tried to ambush us! I have something for you, Sire. I managed to take it from Methven. Rise. You look after this for me. Youve done a grand job so far. I'll guard it with my life. It's good to have you back. It's all right. All's well, Elizabeth. You're here! It's all right. We missed you.

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clcpp-minimal-timer_0.9.2-2 \ examples/examples-rclcpp-multithreaded-executor_0.9.2-2 \ examples/examples-rclpy-executors_0.9.2-2 \ examples/examples-rclpy-minimal-action-client_0.9.2-2 \ examples/examples-rclpy-minimal-action-server_0.9.2-2 \ examples/examples-rclpy-minimal-client_0.9.2-2 \ examples/examples-rclpy-minimal-publisher_0.9.2-2 \ examples/examples-rclpy-minimal-service_0.9.2-2 \ examples/examples-rclpy-minimal-subscriber_0.9.2-2 \ geometry2/examples-tf2-py_0.13.4-2 \ fastcdr/fastcdr_1.0.13-2 \ fastrtps/fastrtps_2.0.0-4 \ rosidl-typesupport-fastrtps/fastrtps-cmake-module_1.0.1-2 \ filters/filters_2.0.0-2 \ fmilibrary-vendor/fmilibrary-vendor_0.2.0-2 \ foonathan-memory-vendor/foonathan-memory-vendor_1.0.0-2 \ geographic-info/geodesy_1.0.4-2 \ geographic-info/geographic-info_1.0.4-2 \ geographic-info/geographic-msgs_1.0.4-2 \ common-interfaces/geometry-msgs_2.1.0-1 \ geometry2/geometry2_0.13.4-2 \ googletest/gmock-vendor_1.8.9000-2 \ google-benchmark-vendor/google-benchmark-vendor_0.0.2-1 \ gps-umd/gps-msgs_1.0.3-2 \ gps-umd/gps-tools_1.0.3-2 \ gps-umd/gps-umd_1.0.3-2 \ gps-umd/gpsd-client_1.0.3-2 \ googletest/gtest-vendor_1.8.9000-2 \ rosidl-typesupport-gurumdds/gurumdds-cmake-module_1.0.2-1 \ ifm3d-core/ifm3d-core_0.18.0-5 \ image-common/image-common_2.3.0-2 \ vision-opencv/image-geometry_2.2.1-1 \ image-pipeline/image-pipeline_2.1.1-2 \ image-pipeline/image-proc_2.1.1-2 \ image-pipeline/image-publisher_2.1.1-2 \ image-pipeline/image-rotate_2.1.1-2 \ demos/image-tools_0.10.0-1 \ image-common/image-transport_2.3.0-2 \ image-transport-plugins/image-transport-plugins_2.3.0-2 \ image-pipeline/image-view_2.1.1-2 \ interactive-markers/interactive-markers_2.1.2-1 \ demos/intra-process-demo_0.10.0-1 \ joint-state-publisher/joint-state-publisher_2.2.0-2 \ joint-state-publisher/joint-state-publisher-gui_2.2.0-2 \ joystick-drivers/joy_2.4.1-2 \ joystick-drivers/joy-linux_2.4.1-2 \ kdl-parser/kdl-parser_2.4.0-2 \ laser-geometry/laser-geometry_2.2.0-4 \ laser-proc/laser-proc_1.0.1-2 \ launch/launch_0.10.2-2 \ launch-ros/launch-ros_0.10.2-2 \ launch/launch-testing_0.10.2-2 \ launch/launch-testing-ament-cmake_0.10.2-2 \ launch-ros/launch-testing-ros_0.10.2-2 \ launch/launch-xml_0.10.2-2 \ launch/launch-yaml_0.10.2-2 \ lgsvl-msgs/lgsvl-msgs_0.0.3-2 \ resource-retriever/libcurl-vendor_2.3.2-2 \ libg2o/libg2o_2020.5.29-2 \ phidgets-drivers/libphidget22_2.0.2-2 \ libstatistics-collector/libstatistics-collector_1.0.1-2 \ libyaml-vendor/libyaml-vendor_1.0.2-2 \ demos/lifecycle_0.10.0-1 \ rcl-interfaces/lifecycle-msgs_1.0.1-1 \ demos/logging-demo_0.10.0-1 \ navigation-msgs/map-msgs_2.0.2-3 \ marti-messages/marti-can-msgs_1.1.0-2 \ marti-messages/marti-common-msgs_1.1.0-2 \ marti-messages/marti-dbw-msgs_1.1.0-2 \ marti-messages/marti-nav-msgs_1.1.0-2 \ marti-messages/marti-perception-msgs_1.1.0-2 \ marti-messages/marti-sensor-msgs_1.1.0-2 \ marti-messages/marti-status-msgs_1.1.0-2 \ marti-messages/marti-visualization-msgs_1.1.0-2 \ message-filters/message-filters_3.2.4-2 \ navigation-msgs/move-base-msgs_2.0.2-3 \ common-interfaces/nav-msgs_2.1.0-1 \ nodl/nodl-python_0.1.0-2 \ orocos-kinematics-dynamics/orocos-kdl_3.3.1-2 \ osrf-pycommon/osrf-pycommon_0.1.10-2 \ osrf-testing-tools-cpp/osrf-testing-tools-cpp_1.3.2-2 \ ros2-ouster-drivers/ouster-msgs_0.2.0-2 \ perception-pcl/pcl-conversions_2.2.0-2 \ pcl-msgs/pcl-msgs_1.0.0-3 \ demos/pendulum-control_0.10.0-1 \ demos/pendulum-msgs_0.10.0-1 \ perception-pcl/perception-pcl_2.2.0-2 \ performance-test-fixture/performance-test-fixture_0.0.2-1 \ phidgets-drivers/phidgets-accelerometer_2.0.2-2 \ phidgets-drivers/phidgets-analog-inputs_2.0.2-2 \ phidgets-drivers/phidgets-api_2.0.2-2 \ phidgets-drivers/phidgets-digital-inputs_2.0.2-2 \ phidgets-drivers/phidgets-digital-outputs_2.0.2-2 \ phidgets-drivers/phidgets-drivers_2.0.2-2 \ phidgets-drivers/phidgets-gyroscope_2.0.2-2 \ phidgets-drivers/phidget

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the response latency. In our experiments, the Netduino Plus (server) and the notebook (client) were placed close to each other (less than 1 m). ![Response latency *vs.* the number of sensor readings (removed TinySOS).](sensors-15-24343-g015){#sensors-15-24343-f015} 7. Conclusions and Future Work {#sec7-sensors-15-24343} ============================== 7.1. Conclusions {#sec7dot1-sensors-15-24343} ---------------- We conclude this paper in the final section by summarizing the research that has been carried out and outlining the conclusions drawn from the result. We also comment on the limitations and propose areas for future work. We began by choosing a class-1 IoT object as categorized in the framework of Bormann *et al.* \[[@B2-sensors-15-24343]\] for our development platform. Firstly, we equipped the class-1 IoT device with a Bluetooth transceiver in order to establish wireless network within a limited range. We standardized its connection by means of OGC PUCK. Due to the fact that Internet access is a key requirement for IoT devices, we applied additional software components to enhance this functionality for the Bluetooth-enabled PUCK instrument. In the second stage, we removed the intermediary gateway in the path between user and IoT device by developing a web service on a Thing itself. Since device owners or manufacturers might have their own design for data representation, we introduced a lightweight version of the OGC SOS, TinySOS. As a result, the sensor measurements could be accessed remotely in a standardized way simply through a web browser. In accordance to the complicated nature of the OGC SOS, we proposed another approach which was more suitable for the class-1 IoT devices. As such, the third contribution of this research was integrating CoAP into the OGC SOS for which the SOS operations were processed on the CoAP proxy with enough computational resources. Due to the UDP transmission, CoAP could not establish a direct connection to the Internet components without the deployment of CoAP proxies. As the IoT will eventually follow the Internet protocol suite model, it is recommended to adjust network connections to be compatible with the Internet standard protocols. As a result, we designed a new application programming interface called OGC SensorThings API. The use cases of this API started with device registrations to the service. For the sensing devices, registration information contained the phenomenon that was observed. After registration, sensing devices could start uploading their observations to the data service. From the point of view of tasking, actuators could also register and publish their tasking capabilities to the data service. As a result, users were able to access those observations and also send controlling tasks to the devices through the service. All the communications with the data service followed the REST-like architecture. Finally, the four implementations on a class-1 IoT object (Netduino Plus) were assessed comparatively. Each implementation was evaluated according to memory occupation (RAM and ROM), request size, response length and response latency. As a case study, we embedded multiple meteorological sensors, sound pressure sensor and LED actuator to our Netduino Plus in order to demonstrate how different components work together. In summary, each of the protocols discussed in this research has its own negative and positive attributes which can effectively influence the protocol selection for application developers. According to the evaluation results, TinySOS and PUCK appeared significantly efficient in terms of ROM usage whilst the SOS over CoAP and the SensorThings API performed slightly better for RAM usage. Thus, PUCK and TinySOS are better candidates for memory-constrained applications. In terms of bandwidth efficiency, the experiments nominated CoAP and SensorThings which had small request and response sizes. Lastly, for real-time applications, TinySOS is not recommended at all since handling large XML documents is time-consuming for resource-constraint devices. 7.2. Future Work {#sec7dot2-sensors-15-24343} ---------------- This paper takes a practical approach to the interoperability in the Internet of Things. There are several ways in which this research can be improved and extended. In this section, some of the major issues that can later be investigated and guidelines of the future work are addressed. First of all, the aforementioned interoperable protocols follow the client-server architectural style which has the single point of failure (SPOF) issue \[[@B45-sensors-15-24343]\]. In order to address this issue, one potential solution is to design a peer-to-peer (P2P) architecture as it has been proven reliable and effective. In this case, devices can form an overlay network to discover resources and forward requests; so a centralized component such as the sensor registry service, CoAP proxy and SensorThings data service would be no longer needed. For this research, Bluetooth and Ethernet were considered as the network enablement technologies for IoT devices. Since Wi-Fi is dominant in network communications \[[@B46-sensors-15-24343]\], the study on Wi-Fi communications in the IoT is strongly recommended. One immediate issue in Wi-Fi connection is the transmission of network configuration to the IoT device which has no display equipment and input peripheral. In addition to Wi-Fi as wireless enablement for the IoT, research should be started on improving energy saving on the IoT devices. The first assumption for this research was IoT devices having unlimited power resources; however this assumption may not be true in many cases. Some sensor nodes will be battery-operated \[[@B26-sensors-15-24343]\], so energy is perhaps the most notable constraint for the IoT devices. Furthermore, achievement in Wi-Fi connection of IoT objects leads to removing wires and cords from devices. Therefore, their battery charge must be efficiently conserved to extend the life of the individual sensor nodes, and consequently the entire IoT network. One of the missing metrics in [Section 6](#sec6-sensors-15-24343){ref-type="sec"} was the evaluation of CPU usage in different protocols. The CPU usage refers to how much work a device's processor is doing. The main reason that we did not focus on this criteria in our evaluations was because there was no complex computation performed on the device. For example, in none of the four protocols, the device did not implement any JSON parser or XML parser which is heavy-weight for class-1 IoT devices. However, it is worth to compare the CPU usage for the existing workload of those protocols in the future. More potential future work pertains to privacy and security for IoT devices. We efficiently implemented existing security and privacy mechanisms of the information technology and computer networks on class-1 IoT devices \[[@B47-sensors-15-24343]\]. Although an acceptable level of secure connection in IoT can be achieved, we believe IoT would require specific rules and mechanisms for the successful implementation of this approach. Mohammad Jazayeri and Steve Liang conceived the original idea and investigated the possible solutions. Then, Mohammad designed the architectures and implemented the solutions. In order to evaluate the implementations, Alec Huang and Mohammad designed and performed the experiments. Finally, Mohammad wrote the manuscript which was revised by Alec. The authors declare no conflict of interest. A.1. Sample Requests and Responses Used in [Section 6.2](#sec6dot2-sensors-15-24343){ref-type="sec"} ==================================================================================================== In this section, requests and responses of the get observation operation for each of the four implemented protocols are presented. A.1.1. Simple Web Server ------------------------ ![HTTP GET request and response to the simple web server through the Internet.](sensors-15-24343-g016){#sensors-15-24343-f016} A.1.2. PUCK over Bluetooth -------------------------- ![GETREADING request and response to the PUCK-enabled Netduino Plus through Bluetooth.](sensors-15-24343-g017){#sensors-15-24343-f017} A.1.3. TinySOS -------------- ![GetObservation request to TinySOS using the 52 North test client tool.](sensors-15-24343-g018){#sensors-15-24343-f018} A.1.4. SOS over CoAP -------------------- ![GetObservation request to the SOSCoAP proxy using 52 North test client tool.](sensors-15-24343-g019){#sensors-15-24343-f019} ![GetObservation request to a CoAP server (*i.e.*, Netduino Plus) using the SOSCoAP Proxy.](sensors-15-24343-g020){#sensors-15-24343-f020} A.1.5. OGC SensorThings API --------------------------- ![HTTP GET request and response to the OGC SensorThings through the Internet.](sensors-15-24343-g021){#sensors-15-24343-f021} ![Summarized response of the SensorThings.](sensors-15-24343-g022){#sensors-15-24343-f022} ![Response of the SensorThings to multiple readings request.](sensors-15-24343-g023){#sensors-15-24343-f023} Posts Unless you’ve been under a rock or living in a cave, you’ve heard of the flap over Sony Pictures release of the new film The Interview starring Seth Rogen and James Franco. The comedy centers on a plan to assassinate North Korean dictator Kim Jong-Un. “The Interview” has been released despite threats. (Credit: tech

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and people with chronic conditions, such as heart disease, diabetes, and lung disease, are at higher risk of getting very sick from this illness. Although it is possible for everyone, including young people, to be affected, your individual risk is low.LATEST FROM THE CDC Watch for Symptoms People with COVID-19 have had a wide range of symptoms reported – ranging from mild symptoms to severe illness. Symptoms may appear 2-14 days after exposure to the virus. People with these symptoms or combinations of symptoms may have COVID-19: Fever Cough Shortness of breath or difficulty breathing Or at least two of these symptoms: Fever Chills Repeated shaking with chills Muscle pain Headache Sore throat New loss of taste or smell Purple or red bumps on toes, hands or feet If you are experiencing these symptoms, or have any other unusual symptoms, contact our office. *Emergency warning signs include difficulty breathing, persistent pain or pressure in the chest, new confusion, or bluish lips or face. If you develop emergency warning signs for COVID-19 get medical attention immediately. Take Precautions The best way to prevent illness is to avoid being exposed to this virus. We strongly recommend the following: If you have any flu-like symptoms, such as fever, a dry cough and/or shortness of breath, contact us.Blake Byrnes Blake Byrnes is a founding partner and CTO of BlueFletch, a 25-person boutique consulting firm focused on mobile solutions. Blake has a background architecting big web systems and hands-on experience with the major mobile platforms. He has built large scale mobile solutions for big companies and brought product concepts to life for startups. Blake has started three companies in the past seven years. Prior to BlueFletch, he was founder and CEO of CrowdMind, co-founder of Less Meeting and managed teams as a consultant with Accenture. He graduated from the Duke University with a degree in Computer Science.The statements in this section merely provide background information related to the present disclosure and may not constitute prior art. Automotive vehicles typically utilize an internal combustion engine to provide the power to operate the vehicle. Internal combustion engines generate heat due to the combustion process and it is necessary to continuously remove the excess heat from the vehicle's engine in order to maintain the operating temperature of the vehicle's engine at a specified level. The usual method of removing this excess heat is an automotive cooling system. The cooling system utilizes a coolant pump which pumps coolant through the vehicle's engine to absorb the excess heat and then this heated fluid is pumped to a heat exchanger or radiator which removes the excess heat by performing a heat exchange process with ambient air. The coolant which has been cooled by the radiator is returned to the engine and the process continuously repeats itself. Typically, the temperature of the coolant is maintained at a minimum level using a thermostat or some other type of control system. In order to reduce the size and thus the costs of the radiator, the automotive designer strives to have the radiator operate in the most efficient manner. One method used to maximize the efficiency of the radiator is to control the flow of ambient air through the radiator. This is accomplished by providing a fan which draws the ambient air through the radiator and then providing a fan shroud which ensures that the maximum amount of air is drawn through the radiator. The maximization of ambient air flow requires that the fan be located within the fan shroud. A common problem with fans is the noise they generate during operation. The noise components generating the sound radiated by the cooling fan are tonal and overall noise. Tonal noise is a result of the rotation of the fan blades. Both tonal and overall noise are equally important for most cooling fans. Obstacles upstream and downstream of the fan create airflow disturbance and induce pressure fluctuation. Fan noise is typically caused by wall pressure fluctuation in the fan and shroud. This noise issue can be addressed by configuring the fan shroud to release this pressure thereby reducing the noise radiating from the cooling fan. The shroud must keep the same or equivalent airflow performance of the old design.'Same state, different world' The story on the southward migration of the “cultural Mason-Dixon line” brought to mind a visit to Richmond that my wife and I, then recent transplants from the Northeast, made years back. During a tour of the state Capitol, the guide asked people in the group where they were from. Several out-of-state locations were mentioned before she came to us. “Fairfax,” we replied. “Ah, yes,” she said. “Same state, different world.”The pinstriped teammate treaty between Kevin Youkilis, the Yankees’ new third baseman and former Red Sox star, and Joba Chamberlain, once suspended for firing two fastballs over Youkilis’s head, evolved from a kindergarten spat compared with what went on between Carl Furillo and his longtime tormentor, the New York Giants right-hander Sal Maglie, before they suddenly became teammates on the Brooklyn Dodgers in 1956. In the first part of the 1950s, the Dodgers and the Giants won six consecutive National League pennants between them — the Dodgers four and the Giants two. They were raging rivals who, to be polite, didn’t like each other, and they demonstrated that dislike in 22 regular-season games every year. “Except for an occasional hello to Gil Hodges, when we’d walk past the Dodgers going to and from our clubhouses under the stands at Ebbets Field, I never spoke to any of them,” Bobby Thomson, whose home run won the 1951 pennant for the Giants, once said. “We just didn’t like each other.” Of all the Dodgers, Furillo, in particular, didn’t like the Giants. He didn’t like Leo Durocher, their manager. He didn’t like Maglie, the Giants ace known as Sal the Barber for how his pitches shaved opposing batters’ chins.1. Field of the Invention This invention relates to a method of taping a harness comprising a bundle of cables, and a machine therefor. 2. Summary of the Prior Art In French patent application FR 2 707 828, a method and apparatus for making a harness comprising electrical wires or other types of wires is described. The method described in the latter patent is particularly adapted for linear harness making machines comprising conveyor systems arranged in a straight line, that transport the harness therealong for processing. In the latter patent, the method is particularly concerned with manufacturing of a complex harness with a number of branches leading to various connection ends, where branches are held together at their joining points or nodes. In order to neatly branch off wires at a node, the harness is taped or tied at the nodes. Long sections of wires between nodes are however not held together, although the harness could be taped at intermediate positions between the nodes. It is however desirable in certain applications to keep the wires bundled together along the whole length between nodes, as exposed individual wires can get: caught on external objects. It may also be desirable to tape the whole harness with a protective layer to prevent damage to individual wires. In the event that taping of the whole harness is desired, it is typical to take a harness, for example which is prepared by the method in the above mentioned patent, or which is manufactured manually on a wiring board, and transport the harness to a taping machine. A known taping device 10 is shown in FIGS. 1a and 1b. The device comprises a static support 1 with a bearing 6, within which a large wheel 2 is rotatably mounted, further comprising a tape roll 3 mounted on an axis 7 pivotally to the wheel 2 and comprising a tape 5. The tape is spiralled around a section 4 of harness comprising a plurality of wires (not shown). The wheel 2 and support 1 have a U-shaped slot 8 to enable the harness section 4 to be positioned in alignment with the axis of the wheel. The wheel can then be rotated in the rotation direction R whilst the harness is fed in the axial direction such that the tape unrolls from the roll 3 and winds in a spiral around the harness. The section of harness to be taped, is supported typically by two grippers at either end, for example, positioned proximate nodes of the harness, the grippers being pulled apart to straighten the cable. The harness is manually fitted to the grippers, but the axial feeding and rotation of the wheel may be motor driven. The above method only enables a single section of harness between nodes to be taped, without intervention of an operator. An operator has to remove and reset the tape in the grippers when another section of the cable between different nodes, must be taped. This is a labour intensive and therefore costly procedure. Due to the complexity of certain harnesses with different numbers of nodes and branches and lengths of harness between the nodes, a solution for automating the taping procedure in a sufficiently simple and viable manner has not been found. Intervention of an operator to reposition the harness on the guides for each section of harness between nodes has the advantage of at least being a simple procedure with great flexibility (i.e. different cables can be easily treated in small production runs). A further problem of the prior method, is also the possibility of inconsistent quality and therefore in certain cases defects in the harness. It would however be desirable to render the harness making procedure less labour intensive, in a cost effective manner, whilst ensuring flexibility, simplicity and reliability of the harness making procedure. 234 S.C. 330 (1959) 108 S.E.2d

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prevalent, if not more so. Linked data is not just the purview of Library Land and a few computer scientists. Linked data has caught the attention of a much wider group of people, albiet the subject is still a bit esoteric. I know the technology supporting linked data functions. After all, it is the technology of the Web. I just wonder if: 1) there will ever be a critical mass of linked data available in order to fulfill its promise, and 2) will we — the information community — be able to overcome the “Tower of Babel” we are creating with all the the various ontologies we are sporting. A single ontology won’t work. Just look at Dublin Core. Many ontologies won’t work either. There is too much variation and too many idiosyncrasies in real-world human language. I don’t know what the answer is. I just don’t. Despite some of my misgivings, I think the following quote by Martin Malmsten pretty much sums up much of the conference — Linked data or die! One Response to “Semantic Web in Libraries 2013” PROV-O doesn’t offer much help for making provenance claims about named graphs and triples. The whole infrastructure is document oriented. You can use it to make claims about a serialized RDF document, but that doesn’t really handle the interesting use cases where knowledge about an entity is being formed from a number of different sources (indeed, where the number of different sources is part of the justification leg of the tripos). At the moment there is no specified mechanism for associating provenance with [the IRI associated with a named graph]. One possible approach might be to “push through” provenance assertions made about the IRI to virtual reified triples corresponding to the content; the details are tricky, and RDF reification is almost as annoying when it’s just pretend./* * Copyright (C) 2010 Pengutronix * Uwe Kleine-Koenig <u.kleine-koenig@pengutronix.de> * * This program is free software; you can redistribute it and/or modify it under * the terms of the GNU General Public License version 2 as published by the * Free Software Foundation. */ #include <linux/dma-mapping.h> #include <asm/sizes.h> #include <mach/mx28.h> #include <mach/devices-common.h> #define mxs_fec_data_entry_single(soc, _id) \ { \ .id = _id, \ .iobase = soc ## _ENET_MAC ## _id ## _BASE_ADDR, \ .irq = soc ## _INT_ENET_MAC ## _id, \ } #define mxs_fec_data_entry(soc, _id) \ [_id] = mxs_fec_data_entry_single(soc, _id) #ifdef CONFIG_SOC_IMX28 const struct mxs_fec_data mx28_fec_data[] __initconst = { #define mx28_fec_data_entry(_id) \ mxs_fec_data_entry(MX28, _id) mx28_fec_data_entry(0), mx28_fec_data_entry(1), }; #endif struct platform_device *__init mxs_add_fec( const struct mxs_fec_data *data, const struct fec_platform_data *pdata) { struct resource res[] = { { .start = data->iobase, .end = data->iobase + SZ_16K - 1, .flags = IORESOURCE_MEM, }, { .start = data->irq, .end = data->irq, .flags = IORESOURCE_IRQ, }, }; return mxs_add_platform_device_dmamask("imx28-fec", data->id, res, ARRAY_SIZE(res), pdata, sizeof(*pdata), DMA_BIT_MASK(32)); }       [< Previous](../reverse-string "Reverse String") 　　　　　　　　　　　　　　　　 [Next >](../moving-average-from-data-stream "Moving Average from Data Stream") ## [345. Reverse Vowels of a String (Easy)](https://leetcode.com/problems/reverse-vowels-of-a-string "反转字符串中的元音字母") <p>Write a function that takes a string as input and reverse only the vowels of a string.</p> <p><strong>Example 1:</strong></p> <pre> <strong>Input: </strong><span id="example-input-1-1">"hello"</span> <strong>Output: </strong><span id="example-output-1">"holle"</span> </pre> <div> <p><strong>Example 2:</strong></p> <pre> <strong>Input: </strong><span id="example-input-2-1">"leetcode"</span> <strong>Output: </strong><span id="example-output-2">"leotcede"</span></pre> </div> <p><b>Note:</b><br /> The vowels does not include the letter "y".</p> <p> </p> ### Related Topics [[Two Pointers](../../tag/two-pointers/README.md)] [[String](../../tag/string/README.md)] ### Similar Questions 1. [Reverse String](../reverse-string) (Easy) 1. [Remove Vowels from a String](../remove-vowels-from-a-string) (Easy) #ifndef _TRANSFORM_TEST_DATA_H_ #define _TRANSFORM_TEST_DATA_H_ /*--------------------------------------------------------------------------------*/ /* Includes */ /*--------------------------------------------------------------------------------*/ #include "arr_desc.h" #include "arm_math.h" /*--------------------------------------------------------------------------------*/ /* Macros and Defines */ /*--------------------------------------------------------------------------------*/ #define TRANSFORM_MAX_FFT_LEN 4096 #define TRANFORM_BIGGEST_INPUT_TYPE float32_t /*--------------------------------------------------------------------------------*/ /* Variable Declarations */ /*--------------------------------------------------------------------------------*/ /* Lengths are multiplied by 2 to accomodate complex numbers*/ extern float32_t transform_fft_output_fut[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_output_ref[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_input_fut[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_input_ref[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_output_f32_fut[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t transform_fft_output_f32_ref[TRANSFORM_MAX_FFT_LEN * 2]; extern float32_t * transform_fft_inplace_input_fut; extern float32_t * transform_fft_inplace_input_ref; extern float32_t transform_fft_f32_inputs[TRANSFORM_MAX_FFT_LEN * 2]; extern q31_t transform_fft_q31_inputs[TRANSFORM_MAX_FFT_LEN * 2]; extern q15_t * transform_fft_q15_inputs; extern q15_t dct4_transform_fft_q15_inputs[TRANSFORM_MAX_FFT_LEN * 2]; /* FFT Lengths */ ARR_DESC_DECLARE(transform_radix2_fftlens); ARR_DESC_DECLARE(transform_radix4_fftlens); ARR_DESC_DECLARE(transform_rfft_fftlens); ARR_DESC_DECLARE(transform_rfft_fast_fftlens); ARR

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"><span style="color: #006600;"><span style="color: black;"></span></span></div><div align="justify"><span style="color: #006600;"><span style="color: black;"></span></span></div><div align="justify"><span style="color: #006600;"><span style="color: black;">5. Now this is the moment of truth!! With a knife cut the pudding from the side of the baking pan. Put a nice big plate on top of the bunt backing pan and turn it upside-down and leave it for a while. Don't mess with it, just let the pudding slowly on its own fall down to the plate. If you mess with it it will brake and you will have an ugly pudding. It will fall, trust me and then there it is you beautiful delicious traditional Brazilian pudding. Very very yummy....specially very cold!</span></span><br /></div><div align="justify"><span style="color: #006600;">Agora e o momento da verdade. Com um faca descole as laterais da panela. Num prato grande coloque-o em cima da panela do pudim e vir-o de cabeca para baixo para desformar. Deixe ele cair sozinho, nao bata na panela pois vc pode quebraro pudim e ai vc tem uma meleca de caramelo. Deixe o pudim cair sozinho. E quando ele cair vc tera um lindo pudim com furrinhos que e uma delicia!</span></div><br /><br /><div align="center"><br /><embed flashvars="host=picasaweb.google.com&RGB=0x000000&feed=http%3A%2F%2Fpicasaweb.google.com%2Fdata%2Ffeed%2Fapi%2Fuser%2Fglitterlife.nl%2Falbumid%2F5289133589769511697%3Fkind%3Dphoto%26alt%3Drss" height="267" pluginspage="http://www.macromedia.com/go/getflashplayer" src="http://picasaweb.google.com/s/c/bin/slideshow.swf" type="application/x-shockwave-flash" width="400"></embed> </div>Alexhttp://www.blogger.com/profile/04983060725228328421noreply@blogger.com1tag:blogger.com,1999:blog-5910967346863755132.post-41667541535255064692009-01-01T13:56:00.002+11:002009-01-01T14:28:54.608+11:00Happy New Year!!!!<div align="justify"><a href="http://1.bp.blogspot.com/_N8Lmem60GXk/SVw4SMyyk0I/AAAAAAAALzw/zsDsd66rFDU/s1600-h/IMG_5029.JPG"><img id="BLOGGER_PHOTO_ID_5286161947949175618" style="FLOAT: left; MARGIN: 0px 10px 10px 0px; WIDTH: 150px; CURSOR: hand; HEIGHT: 200px" alt="" src="http://1.bp.blogspot.com/_N8Lmem60GXk/SVw4SMyyk0I/AAAAAAAALzw/zsDsd66rFDU/s200/IMG_5029.JPG" border="0" /></a> We had such a great time last night at Paul's house. It was strange but wonderful to have the passage of the New Year outside having a barbecue in a warm summer night. The memories of when we had our New Year parties in Brazil was present throughout the evening for me. I had very nice fish with some very yummy salad and lots and lots of water and soda. The picture posted on the blog is just for fun....Rob and Paul were smoking cigars and we thought it would be fun to take picture with me with the cigar and beer... so for all of you out there I did not smoke a cigar or drank beer this New Year!!! It was great to be among friends and family and everyone really had a wonderful time. Alice was really enjoying the warm weather and the great food. It really was a perfect evening for all of us! I wish all of you a great 2009 and that this year will bring peace, joy and happiness for all of you who read my blog. Enjoy the slide show...<br /><br /><embed pluginspage="http://www.macromedia.com/go/getflashplayer" src="http://picasaweb.google.com/s/c/bin/slideshow.swf" width="400" height="267" type="application/x-shockwave-flash" flashvars="host=picasaweb.google.com&captions=1&RGB=0x000000&feed=http%3A%2F%2Fpicasaweb.google.com%2Fdata%2Ffeed%2Fapi%2Fuser%2Fglitterlife.nl%2Falbumid%2F5286153427089127857%3Fkind%3Dphoto%26alt%3Drss"></embed><br /></div>Alexhttp://www.blogger.com/profile/04983060725228328421noreply@blogger.com0AC Repair Has your AC unit stopped working? Of course, the Lowcountry summer is officially upon us and that air conditioning unit you’ve forgotten about all winter isn’t cooperating. Well, look no further than Brian’s Mechanical LLC – we’re here to solve your problems! Whether your air conditioning unit has stopped blowing that icy cold air you love so much, or just stopped working at all, Brian’s Mechanical LLC is here serving your AC repair needs. Specializing in commercial and residential HVAC issues Brian’s Mechanical LLC serves the Tricounty area 24 hours a day and 7 days a week.Publisher's Summary Belle Marshall has no desire to be a traditional wife. As the town healer and manager of the boardinghouse, independence is hers; a husband will only get in the way. Still, she's finding Paul Harrington, the local preacher, harder and harder to ignore each day. How can she stop their emerging romance before it begins? Paul Harrington has given up his violent past as a Texas Ranger and turned a new leaf as the town preacher. Still, it's a constant battle to keep his former self from surfacing. Belle Marshall is just the match to set fire to the tinderbox of passions in his heart, but how can he let her in, while keeping the rest of his emotions in check? Belle and Paul will just have to keep apart. But will the rest of the townspeople let them?(* ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ *) (* :Title: SUNTrace *) (* :Author: Rolf Mertig *) (* ------------------------------------------------------------------------ *) (* :History: File created on 21 March '98 at 9:07 *) (* ------------------------------------------------------------------------ *) (* :Summary: calculation of traces of SUNT-matrices (color factors)*) (* ------------------------------------------------------------------------ *) SUNTrace::usage= "SUNTrace[exp] calculates the color-trace."; (* ------------------------------------------------------------------------ *) Begin["`Package`"] End[] Begin["`SUNTrace`Private`"] Options[SUNTrace] = { Explicit -> False }; HoldPattern[SUNTrace[n_, ___Rule]] := SUNN n /; FCPatternFreeQ[{n}, {SUNT}]; (* this is the function which puts everything together ********* *) SUNTrace[expr_Plus, op___Rule] := Map[SUNTrace[#, op]&, expr]; (*new; suggested by Frederik Orellana *) SUNTrace[expr_Times,op___Rule] := (Select[expr, FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&] * SUNTrace[Select[expr,!FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&], op])/; (expr === fcis[expr]) && (Select[expr,!FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&] =!= 1) && (*To avoid infinite recursion. 3/9-2002. Frederik Orellana*) (Select[expr, FreeQ2[#, {SUNT,SUNF,SUND,SUNDelta}]&] =!= 1); HoldPattern[SUNTrace[1.., ___Rule]] = SUNN; HoldPattern[SUNTrace[a_, ___Rule]] := 0 /; MatchQ[a, SUNT[SUNIndex[_]]] && nopat[a] && (fcis[a] === a);

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8 \beta_0 -5\beta_1 -6 \beta_2.$$ In this case, the domain is defined by the matrix $\mathbf{M_D} = \begin{pmatrix} 1 & 0 & 0 \\ 1 & 0 & 1 \\ 1 & 1 & 0 \\ 1 & 1 & 1 \\ \end{pmatrix}$, yielding the boundary conditions $\mathbf{M_D} \boldsymbol{\beta} \geq 0$. Let $\gamma_0 = \beta_0 + \beta_2$, then we can substitute $\beta_0$ by $\gamma_0$ in Equation , obtaining $\ell^* = \log \gamma_0 - 8 \gamma_0 -5\beta_1 + 2 \beta_2$. By Proposition \[prop:maximumpointReverse\], we know that the maximum point must lie in the intersection of two flat boundaries defined by the row vectors of matrix $M_\mathbf{D}$. For step 1 in Algorithm 1 we need to select two other rows from $\mathbf{M_D}$ which, together with $\mathbf{x}$, form an invertible basis matrix $\mathbf{B}$. Denote the $j^{\textrm{th}}$ row of $\mathbf{M_D}$ as $M_j$. Since $\mathbf{x}$ itself corresponds to the second row of $\mathbf{M_D}$, that leaves as possibilities for the second and third row of $\mathbf{B}$: $M_1$ and $M_3$, $M_1$ and $M_4$, and $M_3$ and $M_4$. Of these, calculating $\mathbf{r} = \mathbf{B}^{-1} \mathbf{s}$, we see that $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_1 | M_3 \end{pmatrix}^\top$ yields $\mathbf{r} = (6, -3, 5)^\top$, $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_1 | M_4 \end{pmatrix}^\top$ yields $\mathbf{r} = (1, 2, 5)^\top$, and $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_3 | M_4 \end{pmatrix}^\top$ yields $\mathbf{r} = (3, 2, 3)^\top$. By proposition (\[prop:maximumpoint\]), we demand $\mathbf{r} \geq 0$. That leaves only the combinations $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_1 | M_4 \end{pmatrix}^\top$ and $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_3 | M_4 \end{pmatrix}^\top$ as valid combinations after the first step. The next step is to check whether the corresponding $\mathbf{\beta}$ estimates satisfy the boundary conditions. The first remaining option, $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_1 | M_4 \end{pmatrix}^\top = \begin{pmatrix} 1 & 0 & 1 \\ 1 & 0 & 0 \\ 1 & 1 & 1 \\ \end{pmatrix}$, gives $\mathbf{r} = \begin{pmatrix} 1 \\ 2 \\ 5 \\ \end{pmatrix}$, and $\boldsymbol{\gamma} = \begin{pmatrix} 1 \\ 0 \\ 0 \\ \end{pmatrix}$. The corresponding value of $\mathbf{\beta}$ is given by $\boldsymbol{\beta} = \mathbf{B}^{-1} \boldsymbol{\gamma} = \begin{pmatrix} 0 \\ -1 \\ 1 \\ \end{pmatrix}$, with $\ell^* = -1$. Checking the boundary conditions $\mathbf{M_D} \boldsymbol{\beta} \geq 0$ yields $\mathbf{M_D} \boldsymbol{\beta} = (0, 1, -1, 0)^\top$, a violation for the third row of $\mathbf{M_D}$, so that $\boldsymbol{\beta}$ is not in $\mathbf{D}$ and this solution is not admissible. In our search we would then look for bases including the third row. This coincides with our second remaining option, $\mathbf{B} = \begin{pmatrix} \mathbf{x} | M_3 | M_4 \end{pmatrix}^\top = \begin{pmatrix} 1 & 0 & 1 \\ 1 & 1 & 0 \\ 1 & 1 & 1 \\ \end{pmatrix}$, which gives $\mathbf{r} = \begin{pmatrix} 3 \\ 2 \\ 3 \\ \end{pmatrix}$, and $\boldsymbol{\gamma} = \begin{pmatrix} 1/3 \\ 0 \\ 0 \\ \end{pmatrix}$. The corresponding value of $\mathbf{\beta}$ is given by $\boldsymbol{\beta} = \mathbf{B}^{-1} \boldsymbol{\gamma} = \begin{pmatrix} 1/3 \\ -1/3 \\ 0 \\ \end{pmatrix}$, with $\ell^* = -\log(3) - 1$, which is smaller than the previous value. Checking the boundary conditions $\mathbf{M_D} \boldsymbol{\beta} \geq 0$ yields $\mathbf{M_D} \boldsymbol{\beta} = (1/3, 1/3, 0, 0)^\top$, which is $\geq 0$, so this is the maximum point we want to find. We comment that it is not necessary in step $1$ to find all the valid $\mathbf B$ which yields positive $\mathbf r$ in practice. It is sufficient to find one $\mathbf B$ and go to the next step. We show all the possible $\mathbf B$ of step $1$ in this example just to give a full picture of this algorithm. Simulation {#sec:simulation} ========== The purpose of the simulation study is to show feasibility of our maximum likelihood estimator and compare its performance with the OLS estimator. In our experiment, we assume $\boldsymbol \beta(t) = (0.05,0.02,0.04,0.06,0.08)t$, hence the true hazard $h$ is given by: $$h(t \,|\, \mathbf{x}) = \sum_i \beta_i x_i t= (0.05 + 0.02\ x_1 + 0.04\ x_2 + 0.06 \ x_3 +0.08\ x_4)t.$$ This corresponds to a Weibull distribution with shape $b=2$ and rate $a = (0.05 + 0.02 x_1 + 0.04 x_2 + 0.06 x_3 + 0.08 x_4) / 2$, using the parametrization for the Weibull hazard $h(t; a, b) = a b t^{b-1}$. We started by randomly generating covariate data $\mathbf{x}_i$, for $i=1,\ldots, n$, with $n=500$, with independent uniform distributions on $[0, 1]$. Then, given covariate data $\mathbf{x}_i$, we generated times to event $T_i^*$ according to a Weibull distribution with shape $b=2$ and rate $a = (0.05 + 0.02 x_1 + 0.04 x_2 + 0.06 x_3 + 0.08 x_4) / 2$. For each subject an independent censoring time $C_i$ was generated with uniform distribution over $(2.5,7.5)$, giving a censoring rate of about $22\%$. The observed data are given by event time $t_i = \min(t_i^*, c_i)$, status indicator $\delta_i = I(t_i^* \leq c_i)$, and covariate vector $\mathbf{x}_i$. Two methods are implemented in this experiment to estimate $\boldsymbol{\beta}$: Aalen’s OLS method described in Section \[sub:OLS\], as implemented in the **timereg** package [@martinussen2007dynamic] and the maximum likelihood estimator with domain $\mathbf D$ as we have introduced in Section \[sub:ML\]. We used the estimated $\boldsymbol{\beta}$ to calculate the survival curve without any smoothness. We choose a subject with data of values $x = (0.4,0.6,0.4,0.6)$. Thus the hazard rate of this subject is $$h(t) = (\beta_0(t) + \beta_1(t) 0.4 + \beta_2(t) 0.6 +\beta_3(t) 0.4+\beta_4(t) 0.6)$$ Figure \[fig:expsurCCM\] shows the true survival curve and the estimated survival curves by the two methods, for the first data set of size $n=500$. ![Estimated survival curves by OLS and by MLE[]{data-label="fig:expsurCCM"}](SurC_simu_TG.jpeg){width="80.00000%"} From Figure \[fig:expsurCCM\] we see that the least squares estimator and the maximum likelihood estimator give similar estimates of the survival

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the most recent items in the beginning, maybe categorize it too, and then you can use expandable listview to enhance more the pick item process per category. What's Not Included Travel Insurance Tips for staff Miscellaneous expenses - drinks and souvenirs etc. Meal Plan All meals are included from dinner on day 1 to breakfast on day 8. Accommodation During this holiday the group will spend 2 nights at a comfortable family orientated hotel in Marrakech. This hotel has great gardens to run around in and a swimming pool. In the mountains we stay in a simple gite for 2 nights, which has family rooms with mattresses on the floor. Bedding is provided here but we advise you to take a sheet sleeping bag. In March and October you may also wish to bring a light sleeping bag to supplement the blankets. Rooms in the gite have shared facilities. In Essaouria, we will stay 3 nights in a small hotel with swimming pool just a short distance from the Medina and 2 minutes walk from the beach. Children of 11yrs and under will share with parents in a triple for a family of 3 or a double with 2 extra beds for a family of 4. Children over 12 yrs will share with parents in a triple for a family of 3, or have 2 rooms for a family of 4. Larger family rooms are occasionally available. We will do everything to ensure that you are happy with your rooming allocation. Additional hotel nights are available pre and post the holiday. Hotels are subject to availability and prices may vary.Change Is Never Easy, but It Is Possible: Reflections on Avoidant/Restrictive Food Intake Disorder Two Years After Its Introduction in the DSM-5. One of the most significant changes to the section on Feeding and Eating Disorders in the DSM-5 was that feeding disorder of infancy or early childhood was renamed avoidant/restrictive food intake disorder or ARFID, and the criteria was significantly expanded. This diagnostic category was informed by field studies, analysis, and expert opinion. To date, research exploring the prevalence, clinical characteristics and utility have helped substantiate the recognition and need for the diagnostic category of AFRID as a distinct eating disorder diagnosis in the DSM-5.--- abstract: 'The excitation of Alfvénic waves in the solar spicules due to the localized Alfvénic pulse is investigated. A set of incompressible MHD equations in two dimensional $x-z$ plane with steady flows and sheared magnetic fields is solved. Stratification due to gravity and transition region between chromosphere and corona are taken into account. An initially localized Alfvénic pulse launched below the transition region can penetrate from transition region into the corona. We show that the period of transversal oscillations is in agreement with those observed in spicules. Moreover, it is found that the excited Alfvénic waves spread during propagation along the spicule length, and suffer efficient damping of the oscillations amplitude. The damping time of transverse oscillations elongated with decrease in $k_{b}$ values.' author: - 'H. Ebadi' - 'M. Hosseinpour' - 'Z. Fazel' title: Transverse oscillations in solar spicules induced by propagating Alfvénic pulses --- Introduction {#sec:intro} ============ Spicules are one of the most fundamental components of the solar chromosphere. They are seen in chromospheric spectral lines at the solar limb at speeds of about $20-25$ km s$^{-1}$ propagating from the chromosphere into the solar corona [@Tem2009]. Their diameter and length varies from spicule to spicule having the values from $400$ km to $1500$ km and from $5000$ km to $9000$ km, respectively. The typical lifetime of them is $5-15$ min. The typical electron density at heights where the spicules are observed is approximately $3.5\times10^{16}-2\times10^{17}$ m$^{-3}$, and their temperatures are estimated as $5000-8000$ K [@bec68; @ster2000]. @Kukh2006 [@Tem2007] by analyzing the height series of $H\alpha$ spectra in solar limb spicules observed their transverse oscillations with the estimated period of $20-55$ and $75-110$ s. More recently, @Ebadi2012a based on *Hinode*/SOT observations estimated the oscillation period of spicule axis around $180$ s.\ Despite the large body of theoretical and observational works devoted to the spicules, their ejection mechanism is not clear yet. In other words, observations with high spatial resolutions are needed to distinguish their origin. The Alfvén waves are usual candidates for energy transport from the lower layers of the solar atmosphere to the corona [@De2007; @Tsiklauri2002]. @Hollweg1982 showed that the Alfvén waves may be nonlinearly coupled to fast magnetoacoustic shocks, which may lead to spicule formation. @Cargill1997 performed the numerical simulations of the propagation of Alfvénic pulses in two dimensional magnetic field geometries. They concluded that for an Alfvénic pulse the time at which different parts of the pulse emerge into the corona depends on the plasma density and magnetic field properties. Moreover, they discussed that this mechanism can interpret spicule ejection forced through the transition region. @Kudoh1999 used the random nonlinear Alfvénic pulses and concluded that the transition region lifted up to more than $\sim5000$ km (i.e. the spicule produced). @Del2005 studied the propagation and evolution of Alfvénic pulses through coronal arcades. Their results showed a strong spreading of the initially localized pulses due to variations of Alfvén speed with height and efficient damping of oscillations. In addition, they concluded that the background density and Alfvén speed should be considered as key ingredients in models. @Tem2010 studied the upward propagation of a velocity pulse launched initially below the transition region. The pulse quickly steepens to a shock which may form the spicules. They concluded that such a model may explain speed, width, and heights of classical spicules. @Rae1982 illustrated that impulsive motions may propagate along an intense tube. Information (in the form of a wave front) propagates at the subsonic and subAlfvénic tube speed. As the wave front of an impulsively generated disturbance propagates along the tube, it trails behind it a wake, which oscillates at cut-off frequency. The significance of cut-off frequency depends upon what are the circumstances creating the motions. If disturbances are impulsively generated, then wave propagation occurs and the existence of cut-off frequency is manifest in the creation of an oscillatory wake. @Hasan1999 examined the generation of waves in vertical flux tubes in the magnetic network through the impulsive excitation by granules. The buffering action of a granule on a flux tube at a certain level excites a pulse that travels away from the source region with tube speed. After the passage of the pulse, the atmosphere oscillates at the cut-off period of the mode, with amplitude that slowly decays in time. @Tem2008 concluded that photospheric granulation may excite transverse pulses in anchored vertical magnetic flux tubes. The pulses propagate upward along the tubes while oscillating wake is formed behind the wave front in a stratified atmosphere. The pulses carry almost all the energy of initial perturbations, while the energy in wake oscillations is much smaller.\ In the present work we perform two-dimensional simulations of MHD equations and show that the Alfvénic pulse which is launched below the transition region can excite Alfvén waves and reach the height where spicules are observed. Section $2$ gives the basic equations and theoretical model. In section $3$ numerical results are presented and discussed, and a brief summary is followed in section $4$. Theoretical modeling {#sec:theory} ==================== We keep effects of stratification due to gravity in $2$D x-z plane in the presence of steady flow and shear field. Since the excitation of incompressible Alfvén waves due to Alfvénic pulses is the main goal of this work, so the continuity and energy equations are not considered. The ideal MHD equations used are as follows: $$\label{eq:momentum} \rho(\frac{\partial \mathbf{v}}{\partial t}+ \mathbf{v} \cdot \nabla\mathbf{v}) = -\nabla p + \rho \mathbf{g}+ \frac{1}{\mu}(\nabla \times \mathbf{B})\times \mathbf{B},$$ $$\label{eq:induction} \frac{\partial \mathbf{B}}{\partial t} = \nabla \times(\mathbf{v} \times \mathbf{B}),$$ $$\label{eq:state} p = \frac{\rho RT}{\mu}.$$ Here, $\rho$ is the plasma density; $T$ is the plasma temperature in Kelvin; $R$ is the universal gas constant, and $\mu$ is the mean molecular weight. We assume that the spicules are highly dynamic with speeds that are significant fractions of the Alfvén speed. Perturbations are assumed independent of y, i.e.: $$\begin{aligned} \label{eq:perv} \textbf{v} &=& v_{0} \hat{k} + v_{y}(x,z,t) \hat{j} \nonumber\\ \textbf{B} &=& B_{0x}(x,z) \hat{i

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& 168 & $<$0\ 1.0 & 331 & $<$0\ 1.5 & 723 & $<$0\ 2.0 & 1231 & $<$0\ 3.0 & 2470 & $<$0\ \[tab:f\] [l c c c c c]{} Miras & 11.4$^{\mathrm{a,b}}$ & 10$^{-9}$ & $<$40%$^{\mathrm{d}}$ & $1.14 \times 10^{-8}$ & $<$0.2%\ OH/IR stars & 1.1$^{\mathrm{a,b}}$ & 10$^{-6}$ & 10%$^{\mathrm{d}}$ & $1.1 \times 10^{-6}$ & 4–5%\ M Supergiants & 1–2$^{\mathrm{c}}$ & 10$^{-6}$ & 15–20%$^{\mathrm{e}}$ & $1-2 \times 10^{-6}$ & 7–13%\ Supernovae & n/a & n/a &? & $\sim 4 \times 10^{-7}$ $^ {\mathrm{f}}$&?\ \[tab:injection\] [^1]: Based on observations with ISO, an ESA project with instruments funded by ESA Member States (especially the PI countries: France, Germany, the Netherlands and the United Kingdom) and with the participation of ISAS and NASA Well, that was disgusting! I was in the barn last night, topping up water buckets for the goats. I checked the buck's pail for "berries" and saw a dead rat floating in it. So... I hauled it out, went outside to dump it and poured off some of the water, so it wouldn't be so heavy to carry to a good spot. I see another dead rat! I poured some more water out, and there was a third dead rat in the bucket. Makes me wonder how many more of the buggers I've got in the barn. :grump: Those kittens better get working or I'll take them back as defective. Please tell me your secret!! If I could get 3 Rats in one night without a shotgun and a spotlight I'd be in heaven. Evening intertainment for us is shooting the dumb young ones off the roof of the old shack that was here when we bought the place. Planned to use it for storage but so did they!!!. Dave & Chris in NE Washington State I'm in Northern Ontario and we are having an outbreak of rats in town. It's made the front page of the local paper the last two weeks. I dislike mice and rats are enough to make me completely loopy. Click to expand... Several years ago when we were still on LI, we had an outbreak of mice. They were EVERYWHERE! Even the exterminator across the street and my clean freak friend next door (with 3 cats!) couldn't get rid of them. Even at church, you would be praying at the altar and glance down and a little church mouse would be sashaying by! I wish I had the right kind of gun to blast the bugger that keeps coming and going out of our house. We've had a trap set for almost five days now and the rat by passes it and goes into my bedroom to rip of my socks I've took off that day. I'm missing a pair of socks (taken one night) and one sock from another pair (taken the next night). :grump: Blasted rats! I don't know how the critter is coming and going in and out of the house. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. I wish I had the right kind of gun to blast the bugger that keeps coming and going out of our house. We've had a trap set for almost five days now and the rat by passes it and goes into my bedroom to rip of my socks I've took off that day. I'm missing a pair of socks (taken one night) and one sock from another pair (taken the next night). :grump: Blasted rats! I don't know how the critter is coming and going in and out of the house. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. Click to expand... somewhere along your foundation there is probably a crack or a hole where he gets in. the may also be a hole in the wall behind a piece of furniture. they don't need much of a crack or hole to get in and out. I wish I had the right kind of gun to blast the bugger that keeps coming and going out of our house. We've had a trap set for almost five days now and the rat by passes it and goes into my bedroom to rip of my socks I've took off that day. I'm missing a pair of socks (taken one night) and one sock from another pair (taken the next night). :grump: Blasted rats! I don't know how the critter is coming and going in and out of the house. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. We've had a bad rat problem this year, too. And I mean RATS--big 'ol rats! First they were in the calf barn and around the dog kennels. Ramik bar bait works wonders. It's sort of expensive, but it works. Not by me, they're not! I would never put poison down, with goats, kittens and free-range hens. I've got two little Nigerian Dwarf doelings who can squeeze out of their pen, and the kittens can get anywhere too. I can't see that they'd come all the way from the neighbours just to drink out of my buckets - there's a couple of creeks between us. You might try putting two water buckets out for your goat. Rats seem to follow a rat smell trail and might not go into the other water bucket... then again... who knows. You might have a better rat trap. Click to expand... Four goat pens - four water buckets. Plus rainbarrels and rain bathtubs. I think the rats have enough choice. Hey, I already invented a better mousetrap - take a 5 gallon pail, put about an inch of oats in the bottom. Mice jump in to get grain, can't get a grip to jump out - take cat and hold him so he can grab the mice! Even with all those critters, you could still use bar bait poison. The thing is, you just have to put it in something that the rats can get to, but the animals can't. Example, you could nail the bar bait to a stick of wood and put it in a 4" diameter pipe, at least a yard long. The rats can't hoard it to a place that the animals can get to--they have to eat it on the spot. That diameter pipe ought to be small enough that the kittens can't squeeze into. Now goats, I don't know much about goats. You might have to be more creative to put it somewhere they can't get into. But bar bait is great because you can nail it to something or string it on a wire, i.e., secure it in place so it won't go places you don't intend it to.Q: Registering application to handle USB device attachment I want to add my application to the list of apps Android offers to launch when a digital camera is connected. I've added this to my manifest: <intent-filter> <action android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" /> <meta-data android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" android:resource="@xml/device_filter" /> </intent-filter> And specified a filter (class 6 is digital camera, but I've tried empty filter as well): <resources> <usb-device class="6"/> </resources> It has no effect, my app is still not in that list. What else do I have to do? Note that I'm not interested in the broadcast intent, all I need is to make it to the list of choices for handling the device user is presented with. A: Found the problem. Manifest should be like this: <intent-filter> <action android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" /> </intent-filter> <meta-data android:name="android.hardware.usb.action.USB_DEVICE_ATTACHED" android:resource="@xml/device_filter" /> I. e. meta-data shouldn't be sub-element of intent-filter like I've put it. Increased TNF-alpha and PGI(2), but not NO release from macrophages in 18-month-old rats. TNF-alpha is an important pro-inflammatory mediator that influences host defense against infection and cancer. Previous examinations of TNF-alpha

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success are long. STEPHEN BIDDLE: If I had to put a number to it, maybe it’s a one in ten. Maybe it’s a one in five longshot, if we play our cards right. There’s no question that this is likelier to fail than succeed at this point. DAVID MARTIN: In an effort to wipe out insurgent strongholds, U.S. troops will be moving into parts of Baghdad and the surrounding countryside, where they have never been before. But even with the surge, former marine Bing West says, there aren’t enough troops to chase insurgents all over Iraq. BING WEST: The insurgents move 60 to 100 kilometers in a night. And all of Iraq is so flat, has such terrific highways, that you can scoot very quickly from place to place. MARTIN: According to Biddle, success depends on coercing insurgent factions into accepting a cease fire. BIDDLE: 160,000 troops is not enough to secure the whole country. But it’s a powerful source of sticks and carrots. If we start using it selectively to reward those who cooperate and consider cease fires, and to punish those who don’t. MARTIN: There are cease fire negotiations going on with insurgents, but for now one military officer says, “there out to kill us, we’re out to kill them.” David Martin, CBS News, the Pentagon. ANKARA, Turkey - Turkey has sent large contingents of reinforcement soldiers, tanks and armored personnel carriers to its border with Iraq as debate heated up over whether to stage a cross-border offensive to hit Kurdish rebel bases. Prime Minister Recep Tayyip Erdogan on Tuesday urged the United States and Iraq to destroy bases of the Kurdistan Workers Party, or PKK, in northern Iraq as Turkish military deployed more tanks and soldiers on the border. The images of military trucks rumbling along the remote border with Iraq's Kurdish zone and tanks being transferred on trains and trucks to beef up an already formidable force there have occupied television screens and front pages of several newspapers in the last few weeks. The Turkish military has said it routinely reinforces the border with Iraq in the summer to prevent infiltrations by the guerrillas. "The PKK must be eliminated as a problem between Iraq and Turkey," Turkey's special envoy to Iraq, Oguz Celikkol, told CNN-Turk television on Wednesday before a visit to Iraq to discuss Turkish demands that Iraq and U.S. forces crack down on the group..... Tuesday, May 29, 2007 The odd thing is that conservatives wear pinstriped suits, when they really should be walking around in togas. The main contribution of the Greeks to modern American politics may have been Michael Dukakis, who once climbed the Acropolis in wingtips. But that doesn’t stop conservatives — especially the Straussians who pushed for going into Iraq — from being obsessed with ancient Greece, and from believing that they are the successors to Plato and Homer in terms of the lofty ideals and nobility and character in American politics — while Democrats merely muck about with policies for the needy. Harvey Mansfield, a leading Straussian who teaches political science at Harvard and who wrote a book called “Manliness” (he’s for it), gave the Jefferson lecture recently at the National Endowment for the Humanities in Washington. It was an ode, as his book is, to “thumos,” the Greek word that means spiritedness, with flavors of ambition, pride and brute willfulness. Thumos, as Philip Kennicott wrote in The Washington Post, “is a word reinvented by conservative academics who need to put a fancy name on a political philosophy that boils down to ‘boys will be boys.’ ” Mr. Mansfield did not mention the war, which is a downer at conclaves of neocons and thumos worshippers. But he explained that thumos is “the bristling reaction of an animal in face of a threat or a possible threat.” In thumos, he added, “we see the animality of man, for men (and especially males) often behave like dogs barking, snakes hissing, birds flapping. But precisely here we also see the humanity of the human animal” because it is reacting for “a reason, even for a principle, a cause. Only human beings get angry.” The professor used an example, naturally, from ancient Greece to explain why politics should be about revolution rather than equilibrium: “What did Achilles do when his ruler Agamemnon stole his slave-girl? He raised the stakes. He asserted that the trouble was not in this loss alone but in the fact that the wrong sort of man was ruling the Greeks. Heroes, or at least he-men like Achilles, should be in charge rather than lesser beings like Agamemnon who have mainly their lineage to recommend them and who therefore do not give he-men the honors they deserve. Achilles elevated a civil complaint concerning a private wrong to a demand for a change of regime, a revolution in politics.” Mr. Mansfield concluded: “To complain of an injustice is an implicit claim to rule.” The most recent example of the Hellenization of the Bush administration is the president’s choice for war czar, Army Lt. Gen. Douglas Lute, who says he loves the Greek military historian Thucydides. Other Thucydides aficionados include Victor Davis Hanson, who was a war-guru to Dick Cheney when the vice president went into the bunker after 9/11 and got into his gloomy Hobbesian phase. (Hobbes’s biggest influence was also Thucydides.) Donald Kagan, a respected Yale historian who has written authoritatively on the Peloponnesian War, is the father of Robert Kagan, a neocon who pushed for the Iraq invasion, and Frederick Kagan, a military historian who urged the surge. I called Professor Kagan to ask him if Thucydides, the master at chronicling hubris and imperial overreaching, might provide the new war czar with any wisdom that can help America sort through the morass of Iraq. Very much his sons’ father, the classicist said he was disgusted that the White House, after a fiasco of an occupation designed by Rummy, “is still doing one dumb thing after another” by appointing General Lute, a chief skeptic of the surge. Professor Kagan said that one reason the Athenians ended up losing the war was because in the Battle of Mantinea in 418 B.C. against the Spartans, they sent “a very inferior force” and had a general in command who was associated with the faction that was against the aggressive policy against the Spartans. “Kind of like President Bush appointing this guy to run the war whose strategy is opposed to the surge,” he said dryly. With cold realism, Thucydides captured the Athenian philosophy in the 27-year war that led to their downfall as a golden democracy: “The strong do what they can and the weak suffer what they must.” What message can we take away from Thucydides for modern times? “To me,” Professor Kagan said, “the deepest message, the most tragic, is his picture of civilization as a very thin veneer. When you punch a hole in it, what you find underneath is hollow, the precivilized characteristics of the human race — animalistic in the worst possible way.” I thought this regime was powerful and self-confident, and actually felt strengthened since we destroyed its two main enemies — the Taliban and Saddam. That could not be further from the truth. This Iranian regime is afraid of its shadow. How do I know? It recently arrested a 67-year-old grandmother, whom it accused of trying to bring down the regime by organizing academic conferences! Yes, big, tough President Mahmoud Ahmadinejad — the man who shows us how tough he is by declaring the Holocaust a myth — had his goons arrest Haleh Esfandiari, a 67-year-old scholar, grandmother and dual Iranian-U.S. citizen, while she was visiting her 93-year-old mother in Tehran. Do you know how paranoid you have to be to think that a 67-year-old grandmother visiting her 93-year-old mother can bring down your regime? Now that is insecure. It’s also shameful. Haleh directs the Middle East program of the Woodrow Wilson International Center for Scholars in Washington. She went to Iran in December to visit her aging mother — a trip she’s made regularly for the past decade. According to her husband, Shaul Bakhash, himself a renown Iran expert in the U.S., while Haleh was traveling to the Tehran airport on Dec. 30, to return home, she was stopped by three masked, knife-wielding men — Iran’s Intelligence Ministry always needs three men and three knives when confronting a grandmother — and they stole her belongings and her U.S. and Iranian passports. This was followed by six weeks of intermittent questioning by Iran’s Ministry of Intelligence. Then, on May 7, Haleh was arrested. Yesterday, she was formally charged with “endangering national security through propaganda against the system and espionage for foreigners,” an Iranian spokesman said — apparently because of her work organizing academic conferences of Iranian and U.S. experts. Why does Iran’s leadership do such a thing?

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Epstein-Barr virus (EBV) lytic phase are important predictive markers for nasopharyngeal carcinoma (NPC) risk. Several lifestyle factors, including smoking, have also been associated with NPC risk. We hypothesized that some specific lifestyle factors induce transformation of EBV from the latent to the lytic stage and contribute to NPC occurrence. We conducted a case-control study using data from male case patients (n = 1316) and control subjects (n = 1571) living in Guangdong Province, an area in China at high risk for NPC, to study potential NPC risk factors and EBV inducers. Two independent healthy male populations from a second high-risk area (n = 1657) and a low-risk area (n = 1961) were also included in the analysis of potential EBV inducers using logistic regression models. In vitro assays were performed to investigate the effect of cigarette smoke extract on EBV activation in two EBV-positive cell lines. All statistical tests were two-sided. Smoking was associated with an increased risk of NPC among the Guangdong participants with 20-40 and 40 or more pack-years vs never smokers (OR = 1.52, 95% CI = 1.22 to 1.88 and OR = 1.76, 95% CI = 1.34 to 2.32, respectively; P (trend) <.001). Smoking was the only factor linked to EBV seropositivity among the expanded control group and the independent low-risk population. In vitro experiments showed that cigarette smoke extract promoted EBV replication, induced the expression of the immediate-early transcriptional activators Zta and Rta, and increased transcriptional expression levels of BFRF3 and gp350 in the lytic phase. Smoking is not only associated with NPC risk in individuals from China but is also associated with EBV seropositivity in healthy males and is involved in EBV activation.Health Insurance What is Health/Medical Insurance? The cost involved in health care today is extremely high and continuously increasing, which is where health/medical insurance becomes important. Medical emergencies can happen at any moment, and besides the impact on one’s health, these emergencies can have a major impact on the financial standings of an individual or a family. Medical insurance covers the financial loss during emergencies (or even non emergencies) and when a person gets sick. Health/Medical insurance is insurance against the risk of incurring medical expenses whether it is individuals or corporations that are paying for the medical insurance expenses. It is the coverage that provides the payments of benefits as a result of sickness or injury. How does Health/Medical Insurance work? Different types of insurance providers exist. There are local (UAE) providers and international providers such as BUPA, AETNA, and Now Health among others, which UAE residents can enroll in. Naturally, differences exist between local providers and international providers; International providers offer a high degree of coverage in terms of: the sum insured (total insurance amount) the annual limit they may offer more benefits and more extensive coverage (i.e. cancer care) Global coverage Streamlined, simple and effective reimbursement procedures Local providers provide the needed coverage and do a good job at it. Variations also exist within local providers depending on the coverage plan a person opted for. When it comes to Dubai, the Dubai Health Authority (DHA) mandates the minimum requirements for medical insurance for Dubai residents. All insurance companies have to be DHA compliant and the requirements include: A minimum of AED150,000 per year of coverage Mandatory maternity coverage Declared pre-existing conditions are covered No age limit when issuing a policy. Historically, insurers could have declined providing coverage after a certain age. Why would you need Health/Medical Insurance? Health Insurance provides a wide range of benefits to its subscribers, those include: Coverage for inpatient (when one has to stay at a hospital) and day-patient treatment in a hospital Coverage for outpatient visits (when you visit to a clinic) or a hospital Maternity coverage – there are several levels of maternity care that can be provided and it’s up to the person to choose which type of coverage suits them best (however there is a minimum amount that has to be provided for Dubai according to DHA) Organ transplants can be covered Cancer treatment can be provided Cover for newborn babies is available Reconstructive surgery can be covered if needed Rehabilitation expenses can be covered Emergency dental services Inpatient psychiatric treatmentcan be offered Terminal illness – palliative and hospice care Evacuation and repatriation services Alternative therapy if needed There are many details to Health Insurance and it’s important to clarify these details and get specifics of what you are buying into before deciding on what to enroll in. One will have to read through the summary benefits and the terms & conditions of a policy in order to fully understand its details. It is critical to find an insurance broker that is ready to provide you with the clarity you need, and this is where Petra Insurance Brokers comes in. We provide the clarity that you desire in order to make the right decision and we have been doing it in the UAE since the 1960s. About Petra Petra Insurance Brokers LLC is a company incorporated and existing under the laws of the United Arab Emirates holding UAE Insurance Authority broker license number 147A delightful Inn,beautifully furnished & cared for. Suzette and Roger along with Sabrine ( and Wren of course ) made us feel comfortable and pampered. Perfect location for a visit to Prince Edward County. A Traveller Situated in Belleville, this bed & breakfast is within 6 mi (10 km) of Zwick Centennial Park, Belleville City Hall, and …More The newly renovated room on the 2nd floor was great. It's new and clean. The bed was firm and comfortable. The hotel breakfast was great - simple but enough to eat. The only concern was the doors. When the room or stair doors closes, it closes heavily which can be heard clearly, even inside the room. Traveller from Toronto Located in the heart of Belleville, this eco-friendly hotel is within 2 mi (3 km) of Yardmen Arena, The Empire Theatre, and …More Hotel Brand Belleville is calling — find the perfect hotel Everyone wants to score a deal on travel, but price is just one factor to consider when booking an unforgettable hotel. Whether you’re visiting family, attending a conference or taking a well-earned vacation in Belleville, having an awesome experience should be a no-brainer. Hotwire will hook you up! From restful nights near your flight to that prime spot in the city’s heart, we’ve done our research to bring the best options to your fingertips. Book your Belleville hotel with us now and start your next adventure. You’re not the average traveler — and we know it You’ve done your homework and know exactly where you want to go. We’re here to help with some Hotwire travel geek-approved tips on how to save on your booking. Get away for the weekend Hotels in bigger cities usually charge higher rates during the week, when people are traveling for business. Weekends can be a bargain! It’s the other way around for vacation spots, so if you’re looking for a beach escape, consider a mid-week trip. Give yourself some wiggle room If your plans are flexible, play around with some different travel dates – a shift of a few days either way can help you save big. Prices usually jump the weekends before and after popular holidays, so we recommend steering clear of them. Or consider visiting during the off-season, when prices are generally lower. Plan around big events Are prices surprisingly high? There might be a huge conference or festival in town. Consider shifting your dates if you can. Of course, if that’s why you’re going, you’ll have to bite the bullet. We’ll still work to get you the best rates out there. Noodle over new adventures Set aside time to plan what you want to see, taste and discover. Nothing completes a trip, big or small, like a few new experiences! Check city apps or area websites to find out what’s new and what events are happening during your stay. Even during a family reunion, you can detour to that locals-only fish taco stand or under-the-radar music club. Your cousins will be impressed.Shin To Shin Streaming New Album's Title Track A389 Recordings this week confirms the pending release of the debut LP from Shin To Shin, the side project of guitarist Aaron Melnick. You can hear the title track off the self-titled album below, courtesy of Lambgoat.com. The following press release was also issued about the album: "Aaron Melnick's name is most often associated with the mighty Integrity, having been the lead guitarist for some of their most seminal releases including Those Who Fear Tomorrow, Systems Overload, Humanity Is The Devil and Seasons In The Size Of Days, in addition to contributing vocals, taking part in the arranging, recording and production of said records and much more. His blazing, divebomb-infused solo style seems directly descendant to Metallica and some of the earliest Bay Area thrash heroes, yet fueled for a more deplorable, clenched-fist audience. "Melnick also formed

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right leg. Stretch both legs out into Staff, and bounce your knees on the floor a few times. Repeat the pose for the same length of time with the left leg. Technically, when the right leg is crossed over the left, it's called Right Half-Lotus Pose ( _dakshina ardha padmasana_ ), and when the left is over the right, it's Left Half-Lotus Pose ( _vama ardha padmasana_ ). _**_Practice 2: Full Lotus_**_ From Half-Lotus, lean back slightly, pick the right leg up off the floor, and lift the left leg in front of the right. To do this, hold the underside of the left shin in your hands. Carefully slide the left leg over the right, snugging the edge of the left foot deep into the right groin. Again, swivel into position from the hip joint, press the left heel against the lower right belly, and arrange the sole perpendicular to the floor. Draw the knees as close together as possible. Use the edges of the feet to press the groins toward the floor, and lift through the top of the sternum. Stay for 1 to 3 minutes, then release the legs into Staff and bounce the knees a few times. Repeat with the legs reversed for the same length of time. _**_Traditional Benefit_**_ All three sourcebooks claim that Lotus wards off disease. The _Hatha-Yoga-Pradipika_ and _Shiva-Samhita_ suggest that through working with the breath in Lotus, the practitioner can achieve liberation. LITTLE LAMP: YOGA If I read Gheranda correctly, Yoga Pose is a kind of "loose" Lotus. In his directions for the latter, he says to place each foot on top of the opposite thigh ( _uru_ ), while for Yoga, he says to place each foot on the opposite knee ( _janu_ ). This pose is optional. _**_Practice_**_ Cross each foot over to the opposite thigh, gaze at the tip of the nose, and lay the backs of the hands on the floor outside the hips. _**_Traditional Benefit_**_ Gheranda makes reference to this pose bringing "success" in yoga. **R OOSTER POSE (KUKKUTASANA)** _**_KUKKUTA_**_ • rooster Full Rooster involves slipping the hands and arms between the Lotus-shaped thighs and calves, pressing the hands to the floor, and lifting the torso and legs off the floor. This is beyond the ability of most students, so here we'll perform a "free-arm" variation of Rooster that today is called Scale Pose ( _tolasana,_ literally "poising one's self, weighing"; see _Light on Yoga_ #48). There are two practices, the first for Half-Lotus and the second for full Lotus. If you have trouble lifting off the floor in either version, press each hand against either the side or the face of a yoga block to create more space between you and the floor. _**_Practice 1: Scale in Half-Lotus_**_ In Half-Lotus, you may not be able to quite lift the lower leg off the floor. If not, bind the lower leg to the upper one with a strap. Make a loop, pass it under the bottom foot and over the top leg's inner groin, and snug (but don't tighten) it. Press your hands to the floor beside your hips; lean your torso slightly forward; and firming your lower belly, lift your legs off the floor with an exhalation. Hold for 15 to 30 seconds, then lower lightly back down to the floor. Fig. 14. Rooster Pose ( _kukkutasana_ ). _**_Practice 2: Scale in Full Lotus_**_ The instructions for Scale in Full Lotus are the same as those for Half-Lotus. _**Traditional Benefit**_ None listed. **F ISH POSE (MATSYASANA)** _**_MATSYA_**_ • fish Traditionally, Fish Pose might be called Reclining Lotus, because it's performed as a flat-out supine position with the legs in Lotus (see _Light on Yoga_ #114). In modern yoga, it's sometimes performed as a backbend with the head and legs on the floor, the arms crossed overhead, and the torso arched off the floor ( _Light on Yoga_ #113). Here, we'll work with the traditional flat-out version. If you find it difficult to recline your torso fully on the floor, then you have two choices: you can lie back on some kind of support, such as a bolster or thickly folded blanket, or before you lie back, you can slip your legs out of Half- or full Lotus and simply cross them in Easy Pose ( _sukhasana_ ). LITTLE LAMP: WHY DOES FISH POSE LOOK LIKE A FISH? How or why does this pose look like a fish? This question bothered me for a long time, as I assumed that every pose named after a living creature should look at least vaguely like its namesake. Then I ran across this explanation in _Popular Yoga Asanas_ by Swami Kuvalayananda: "The pose is called Matsyasana because in swimming a person can float on water, like the fish, for a considerable time, if he steadily lies there in this posture." It sounds somewhat plausible, though I'm not sure the pose is really needed if all you want to do is float. Fig. 15. Fish Pose ( _matsyasana_ ). This brings up a question: is floating part of traditional Hatha Yoga? It turns out the answer is yes, at least it was 650 years ago in the time of Svatmarama. His instructions are to swallow a large amount of air into your belly and then you can float ( _plu_ ) happily like a lotus leaf, even in deep ( _agadha_ ) water. This is a _pranayama,_ believe it or not, called Floating ( _plavini_ ). I suppose this practice might have been akin to our current floating in an isolation tank. By the way, can you swallow air? The answer, again, is yes. _**_Practice_**_ In Lotus, exhale, lie back, and cross your forearms overhead, holding each elbow with the opposite hand. Stay in position for up to 1 minute. Bring the torso and head up with an inhalation, leading with your chest if possible and letting your head trail. _**_Traditional Benefit_**_ Fish Pose wards off disease. LITTLE LAMP: UTTANA KURMASANA Raised Tortoise Pose is traditionally performed with the arms inserted through the Lotus legs, just like Rooster. But we'll do it with the arms outside the Lotus legs. This pose is optional. _**_Practice_**_ From Fish, draw the legs in to the torso and wrap the arms around the outer thighs. Stay in this position for one to two minutes. _**Traditional Benefit**_ None listed. SECTION 5: FORWARD BENDS There are four poses in this section: one of them an asana-like mudra ( _maha mudra_ ); one a straight-ahead sitting forward bend; one a pose that changed its shape entirely between the time of Svatmarama and that of Gheranda; and the fourth, which isn't a forward bend but the only real twist in _Gheranda-Samhita._ **G REAT SEAL (MAHA MUDRA)** We'll run into Great Seal again as itself in the next chapter. Here we'll use the position as a jumping-off place for a sitting forward bend we call Head-to-Knee Pose ( _janu shirshasana;_ see _Light on Yoga_ #59). I should note that there's been some controversy about this interpretation of the Sanskrit name in certain quarters of the yoga community—not about _janu_, which everyone agrees means "knee" (and cognate with Latin _genu,_ from which we get "genuflect"), nor over _shirsha,_ which undeniably means "head." The disagreement swirls around the preposition "to," which some believe should be "of," a seemingly slight change with significant implications. Fig. 16. Great Seal ( _maha mudra_ ). According to the latter camp, the expression "head- _to_ -knee" isn't entirely wrong (after all, in the final position of the pose, the practitioner's head is on the straight-leg knee), it just encourages a mistaken idea about the goal of the exercise, especially in beginning students. Hearing "head-to-knee," beginners often take this as a divine command and try, despite their physical limitations such as tight hamstrings, to do just that, resulting in all sorts of strange-looking and potentially injurious forward bends. So the "of" camp maintains that the "head-on-the-top-of-your-shoulders-to-the-straight-

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-feira quatro torres da operadora Vodafone foram no Reino Unido foram incendiadas, e três outras já haviam sido incendiadas anteriormente. A operadora também afirma que seus técnicos e engenheiros estão sendo ameaçados por cidadãos que acreditam que as torres, se forem colocadas em operação, “vão matar todo mundo”. "Sinto informar que vândalos realizaram uma série de ataques criminosos a torres de telefonia celular durante este período de crise nacional", diz Nick Jeffery, CEO da Vodafone UK. “Agora é uma questão de segurança nacional. As autoridades policiais e de combate ao terrorismo estão investigando. ” As principais operadoras de telefonia do Reino Unido (Three, EE, Vodafone e O2) emitiram um comunicado conjunto negando a teoria da conspiração e pedindo ajuda dos consumidores para parar com os ataques. Elas lembram que neste momento, com milhões de pessoas trabalhando remotamente e em isolamento social, suas redes são cruciais para a educação, produtividade, comunicação e entretenimento da população. “É difícil acreditar que algumas pessoas querem prejudicar as redes que estão fornecendo conectividade essencial para os serviços de emergência, o sistema nacional de saúde e o resto do país durante este período de quarentena”, disse Jeffery. YouTube intervém O YouTube decidiu intervir para auxiliar na contenção dos rumores. Vídeos com teorias de conspiração relacionadas à segurança das redes 5G, mas que não mencionem o coronavírus, serão “suprimidos”, através da suspensão de anúncios e de sua eliminação nos resultados de busca da plataforma. Já vídeos que afirmam haver uma ligação entre o vírus e as redes 5G serão removidos da plataforma, já que violam a política da empresa que não permite a divulgação de métodos não comprovados pela comunidade médica para prevenir ou curar a doença. Segundo o YouTube, desde fevereiro milhares de vídeos com informações falsas ou enganosas sobre o coronavírus foram removidos. Entretanto, trata-se de um jogo de gato e rato já que, frequentemente, momentos depois de um vídeo ser removido múltiplas cópias novas aparecem na rede. Mats Granryd, diretor geral da GSMA, organização que representa o interesse de empresas da indústria de telefonia em todo o mundo, disse: “A indústria de telecomunicações está trabalhando dia e noite para manter serviços vitais de saúde, educação e emergência on-line, além de negócios funcionando e amigos e famílias conectados. É deplorável que a infra-estrutura crítica de comunicações esteja sendo atacada com base em tamanhas mentiras. Pedimos a todos que confiem nas autoridades de saúde e tenham certeza de que a tecnologia de comunicação é segura. Não há ligação entre 5G e Covid-19”. Confira em tempo real a COVID-19 no Brasil:Political insiders used to scoff at the idea that Hillary Clinton would choose Elizabeth Warren for her running mate. But multiple reports have found that she's one of the contenders on a shortlist that will soon be vetted by the Clinton team, alongside Virginia Sen. Tim Kaine, Housing and Urban Development Secretary Julian Castro, and potentially others. And on Monday, Clinton and Warren will campaign together at an event in Cincinnati, in what could well be an audition for veep. Many Democratic elites seem to be thrilled about the idea of a Clinton-Warren ticket. In April, the Huffington Post’s Ryan Grim quoted a "member of Clinton’s inner circle" saying, "Real folks are pushing Warren. I’m into it." Allies of Senate Democratic Leader Harry Reid have been very clear to the press that he thinks Warren would be the best choice. But does this pairing make sense — for Clinton, for Warren, for progressives, and for the Democratic Party as a whole? The answer to this question is complicated by the utter strangeness of the vice presidency. The office lacks practically any formal powers, which means that a vice president’s influence depends largely on the president’s whims. Consequently, there are good arguments that Warren can be more powerful if she's not vice president. Some recent vice presidents — most famously Dick Cheney, but also Joe Biden — have had a great deal of influence, though. Plus, there’s the small matter that a twist of fate could make whomever gets the job the most powerful person in the world. And then there’s the fact that many presidential nominees seem to ignore all this in favor of choosing a running mate solely for short-term electoral reasons. So, keeping this complex set of considerations in mind, here are the best arguments Democrats have been making for and against choosing Warren as Clinton’s No. 2. The case for Vice President Warren 1) An important progressive voice would be on the ticket and in a Clinton White House: Symbolically and substantively, a Warren nomination would be a major acknowledgement of progressives’ importance in the modern Democratic Party. She'd be the most liberal vice presidential nominee in decades; her selection could help convince progressives that this Clinton administration won't pivot to the center and leave progressives behind. (After all, Warren would be around to give them hell for it if they do.) Furthermore, Warren has already figured out how to exercise a surprising amount of influence even as a first-term senator — she’s managed to torpedo several high-profile Obama administration appointments. The vice presidential position would give her far more prominence and an even bigger media megaphone. And depending on what President Clinton allowed her to do, Warren could have a great deal of influence on many crucial under-the-radar appointments and administrative matters like Dick Cheney once did. An unleashed Vice President Warren could champion progressive causes and combat corporate lobbyists and moneyed interests throughout the labyrinthine rulemaking process and federal government. 2) She’d unite Democrats, excite Sanders supporters, and turn out the left: With the Bernie Sanders campaign apparently winding down, the question of whether his supporters will rally around Clinton is on many Democrats’ minds. Most party elites currently assume that they will, since Sanders himself is highly likely to endorse her and since stopping Trump seems so important. But much of Sanders’s support was drawn from voters who identified as independents — many of them feel disenchanted by a Democratic Party they view as calcified, corporate, and corrupt. It’s possible that many of them could stay home unless the party makes a major effort to change its image — for instance, by choosing a populist anti–Wall Street crusader like Warren as Clinton's running mate. (A recent poll shows Warren is quite popular among Sanders voters who are currently saying they’ll refuse to support Clinton in the general election.) More broadly, Warren could excite the Democratic base and galvanize turnout on the left — which could make a crucial difference in an increasingly polarized electorate where independent voters are less important. 3) She's an excellent attack dog who gets under Trump's skin: A traditional role of the vice presidential pick is that of the "attack dog" — someone who will aggressively go after the other party’s nominee while theoretically letting his or her own nominee remain at least somewhat above the fray. And if Warren has proved one thing in the past few months, it’s that she’d be a fantastic attack dog against Donald Trump. On Twitter, she’s shown herself to be willing to provoke Trump with a slash-and-burn style. And in a speech earlier this month she tore Trump to shreds, calling him a "thin-skinned, racist bully." Furthermore, Warren really seems to get in Trump’s head, and frequently provokes over-the-top reactions from him. A vice presidential nominee who could drive Trump up the wall and force him to wound himself in response would be great for the Clinton campaign. Watch: Elizabeth Warren goes on attack against Donald Trump 4) She’d get tons of media attention: Relatedly, the Clinton campaign has reportedly been seriously concerned about whether its more traditional, reserved candidate could manage to get comparable coverage in a 24/7 Trump-driven media circus. But Warren is a charismatic personality who can command headlines, as we’ve recently seen — which could prove a potent antidote. 5) An all-woman ticket would make history: Sure, the reaction to Clinton's own historic nomination has been somewhat muted. But the idea of going from no women presidents

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Do you see him whom YEHOWAH has chosen, that there is none like him among all the people?” So all the people shouted and said, “Save the king!” 25 Then Samuel told the people the ordinances of the kingdom, and wrote them in the book and placed it before YEHOWAH. And Samuel sent all the people away, each one to his house. 26 Saul also went to his house at Gibeah; and there went with him a band of men whose hearts Elohim had touched, 27 but the children of Belial said, “How can this one save us?” And they despised him and did not bring him any present. But he kept silent. CHAPTER 11 Then Nahash the Ammonite came up and encamped against Jabesh-gilead; and all the men of Jabesh said to Nahash, “Make a covenant with us and we will serve you.” 2 But Nahash the Ammonite answered them, “I will make it with you on this thing: that I will thrust out all your right eyes, thus I will make it a reproach on all Israel.” 3 The elders of Jabesh said to him, “Leave us alone for seven days, that we may send messengers into all the territory of Israel, and if there is none to save us, we will come out to you.” 4 Then the messengers came to Gibeah of Saul and spoke these words in the ears of the people, and all the people lifted up their voices and wept. 5 And behold, Saul came after the herd from the field, and he said, “What is with the people that they weep?” So they told him the words of the men of Jabesh. 6 Then The Spirit of Elohim came upon Saul mightily when he heard these words, and his anger was kindled greatly. 7 And he took a pair of oxen and cut them in pieces, and sent them throughout the territory of Israel by the hand of messengers, saying, “Whoever comes not forth after Saul and after Samuel, so shall it be done to his oxen.” Then the fear of YEHOWAH fell upon the people, and they came out as one person. 8 And he numbered them in Bezek; and the children of Israel were three hundred thousand, and the men of Yehudah thirty thousand. 9 And they said to the messengers who had come, “Thus you shall say to the men of Jabesh-gilead, ‘Tomorrow, by the time the sun is hot, you will have deliverance.'” So the messengers went and told the men of Jabesh; and they were glad. 10 Then the men of Jabesh said, “Tomorrow we will come out to you, and you may do to us whatever seems good in your sight.” 11 And it came to pass the next morning, that Saul put the people in three companies; and they came into the midst of the encampment, at the morning watch, and struck the Ammonites until the heat of the day. And it was, that those who remained were scattered, so that two of them were not left together. 12 Then the people said to Samuel, “Who said, ‘Shall Saul reign over us?’ Bring those men, that we may put them to death.” 13 But Saul said, “There shall not a man be put to death this day, for today YEHOWAH has brought forth salvation in Israel.” 14 Then said Samuel to the people, “Come and let us go to Gilgal, and renew the kingdom there.” 15 And all the people went to Gilgal, and there they made Saul king before YEHOWAH in Gilgal. There they also sacrificed sacrifices of peace offerings before YEHOWAH; and there Saul and all the men of Israel rejoiced greatly. CHAPTER 12 And Samuel said to all Israel, “Behold, I have heard your voice in all that you said to me, and I have appointed a king over you. 2 And now, behold, the king walks before you, but I am old and gray-headed, and behold my sons are with you. And I have walked before you from my childhood even to this day. 3 Here am I; bear witness against me before YEHOWAH and before His anointed. Whose ox have I taken, or whose ass have I taken, or whom have I defrauded? Whom have I oppressed, or from whose hand have I taken a bribe to blind my eyes with it? I will restore it to you.” 4 And they said, “You have not defrauded us or oppressed us or taken anything from any man’s hand.” 5 He said to them, “YEHOWAH is witness against you, and His anointed is witness this day that you have found nothing in my hand.” And they said, “He is witness.” 6 Then Samuel said to the people, “It is YEHOWAH who appointed Moses and Aaron and who brought your fathers up out of the land of Egypt. 7 And now stand still, that I may plead with you before YEHOWAH, of all the righteous acts of YEHOWAH that He did for you and your fathers. 8 When Jacob went into Egypt and your fathers cried out to YEHOWAH, then YEHOWAH sent Moses and Aaron, who brought your fathers out of Egypt and settled them in this place. 9 But they forgot YEHOWAH their Elohim, so He sold them into the hand of Sisera, captain of the army of Hazor, and into the hand of the Philistines and into the hand of the king of Moab, and they fought against them. 10 And they cried out to YEHOWAH and said, ‘We have sinned, because we have forsaken YEHOWAH and have served Baalim and the Ashtaroth; but now deliver us from the hands of our enemies, and we will serve You.’ 11 Then YEHOWAH sent Jerubbaal and Bedan and Jephthah and Samuel, and delivered you out of the hands of your enemies round about, so that you dwelt in security. 12 And when you saw that Nahash the king of the sons of Ammon came against you, you said to me, ‘No, but a king shall reign over us,’ when YEHOWAH your Elohim was your king. 13 And now behold, here is the king whom you have chosen, whom you have asked for, and behold, YEHOWAH has set a king over you. 14 If you will fear YEHOWAH and serve Him, and hear His voice and not rebel against the commandment of YEHOWAH, then both you and also the king who reigns over you will continue following YEHOWAH your Elohim. 15 But if you will not hear the voice of YEHOWAH, and rebel against the commandment of YEHOWAH, then the hand of YEHOWAH will be against you, as it was against your fathers. 16 Now therefore, take your stand and see the great thing that YEHOWAH will do before your eyes. 17 Is it not wheat harvest today? I will call to YEHOWAH, that He sends thunder and rain. Then you will know and see that your wickedness is great, which you have done in the sight of YEHOWAH by asking for yourselves a king.” 18 And Samuel called unto YEHOWAH, and YEHOWAH sent thunder and rain that day; and all the people greatly feared YEHOWAH and Samuel. 19 And all the people said to Samuel, “Pray to YEHOWAH your Elohim, for your servants, that we die not, for we have added to all our sins this evil by asking for ourselves a king.” 20 And Samuel said to the people, “Fear not. You have done all this evil, yet do not turn aside from following YEHOWAH, but serve YEHOWAH with all your heart; 21 and turn you not aside, to go after vain things that cannot profit or deliver, because they are vain. 22 For YEHOWAH will not forsake His people for His great name’s sake, because YEHOWAH has been pleased to make you His people. 23 Moreover, as for me, far be it from me that I should sin against YEHOWAH by ceasing to pray for you; but I will teach you in the good and right way. 24 Only fear YEHOWAH and serve Him in truth with all your heart; for consider what great things He has done for you. 25 But if you still do wickedly, you will perish, both you and your king.” CHAPTER 13 Saul was thirty years old when he began to reign, and in the second year of his reign, 2 Saul chose him three thousand men of Israel, of which two thousand were with Saul in Mikmas and in the hill country of Bethel, while one thousand were with Yehnathan at Gibeah of Benyahmin. But he sent away the rest of the people, each to their tent. 3 And Yehnathan smote the garrison of the Philistines that was in Geba, and the Philistines heard. Then Saul blew the trumpet throughout the land, saying, “Let the Hebrews hear.” 4 All Israel heard say, that Saul had smitten the garrison of the Philistines, and also that Israel had become odious to the Philistines. The people were called together to Saul at Gilgal. 5 And the Philistines gathered together to fight against Israel; thirty thousand chariots and six thousand horsemen, and people like

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anye's trademark sarcasm also shined through over the course of the grilling. At one point, Goldberg asked Kanye where he lives. "Earth," responded the rapper. Look for more of the deposition to make its way to the web soon. In the meantime, check out this throwback of Lil Wayne's still-hilarious 2012 deposition here.This is a volunteer-run guide that will help you set up a tablet for an elder isolated by COVID. No need to teach the senior how to use any technology. This guide will show you how to configure a tablet to automatically pick up when you initiate a video-call over Skype or Facetime. No WiFi required. This guide will help you buy a tablet from your wireless carrier that connects to the internet over the cellular network. When you've finished preparing the tablet, you can mail it to the elder, and all they have to do is turn it on and plug in the charger. If you have any trouble, you can reach out to our volunteer tech support for help.Scale model «The Gaza Strip is a territory of about 360 square kilometres, running up the Mediterranean coast towards Tel Aviv, bordered to the south by Egypt. It's a strip of land no more than 14km across at its widest point, six at its narrowest, and is said to be the most densely populated piece of earth in the world. It is home to more than a million Palestinians.» #ifndef PRINCIPIA_PHYSICS_BODY_HPP_ #define PRINCIPIA_PHYSICS_BODY_HPP_ #include "base/macros.hpp" #include "base/not_constructible.hpp" #include "base/not_null.hpp" #include "serialization/physics.pb.h" namespace principia { namespace physics { namespace internal_body { using base::not_constructible; using base::not_null; class Body { public: virtual ~Body() = default; // Returns true iff this body is massless. virtual bool is_massless() const = 0; // Returns true iff this body is oblate (which implies massive). virtual bool is_oblate() const = 0; // Returns true iff this body is compatible with the given frame (either // because it is spherical or because its axis is expressed in the same // frame). template<typename Frame> bool is_compatible_with() const; virtual void WriteToMessage(not_null<serialization::Body*> message) const = 0; // Dispatches to one of the subclasses depending on the contents of the // message. static not_null<std::unique_ptr<Body>> ReadFromMessage( serialization::Body const& message); protected: Body() = default; private: // A helper struct which is here just so that we can specialize it on // |is_inertial|. This is necessary because we cannot dynamic cast to // OblateBody<Frame> if |Frame| is not inertial. template<typename Frame, bool is_inertial> struct CompatibilityHelper : not_constructible { static bool is_compatible_with(not_null<Body const*> body); }; }; } // namespace internal_body using internal_body::Body; } // namespace physics } // namespace principia #include "physics/body_body.hpp" #endif // PRINCIPIA_PHYSICS_BODY_HPP_ Kraken’s Honor starts off in the midst of a shipwreck in the middleof a rocky shoal with dry land a mere breadth away. The two survivors are stuck on the prowl of the great ship the Ice Queen as the freezing ocean spray and waves disintegrates the ship around them. Their fate seems sealed, to die smashed against the rocks or in the belly of the Kraken waiting in the shallows. This fateful moment leaves Prince Faeryk with the certainty that he must return to his home of Westever and right the wrongful murder of his father at the hands of his brother, Faeryk’s Uncle. To accomplish this all he can relay on is his bard and friend Halvak, his father’s sword Wavetamer and the Honor of a Kraken. I’ve never had the pleasure to read a story by S. A. Bolich before and I must say I have been missing out. Bolich spins a mesmerizing tale of ancient wrongs and the binds that sins of our forefathers put on us. In this remarkably detailed short story you can’t help but be ensnared by the web of history and the depth of characters that are spun. Truly an excellent story made even more enjoyable by the fact that it is free to read online to everyone over at Beneath Ceaseless Skies.Surgically treatable growth retardation due to non-neoplastic pituitary-hypothalamic dysfunction. Out of 90 children, examined because of growth failure, 15 have been treated surgically. The diagnoses were intrasellar arachnoid diverticulum or empty sella (5 cases), enlarged chiasmatic cisterns (5 cases), chronic 'occult' hydrocephalus (5 cases). Surgery was followed by an immediate increase in growth rate in almost all the cases, even if the result was persistent only in some subjects. In percentage, better results were obtained in patients with enlarged chiasmatic cisterns and chronic occult hydrocephalus than in patients with arachnoid diverticulum or empty sella. The evaluation of prolactin serum levels was demonstrated to be useful both in preoperative diagnosis and postoperative control./****************************************************************************** * * Copyright 2016 Paphus Solutions Inc. * * Licensed under the Eclipse Public License, Version 1.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.eclipse.org/legal/epl-v10.html * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * ******************************************************************************/ package org.botlibre.sense.twilio; import java.io.StringWriter; import java.util.HashMap; import java.util.Map; import java.util.logging.Level; import org.botlibre.api.knowledge.Network; import org.botlibre.api.knowledge.Vertex; import org.botlibre.knowledge.Primitive; import org.botlibre.self.SelfCompiler; import org.botlibre.sense.BasicSense; import org.botlibre.sense.ResponseListener; import org.botlibre.thought.language.Language; import org.botlibre.tool.Date; import org.botlibre.util.Utils; import net.sf.json.JSONObject; import net.sf.json.JSONSerializer; /** * Receive and respond to incoming email. * Can use any pop mail server, such as gmail. */ public class Twilio extends BasicSense { public static int MAX_WAIT = 60 * 1000; // 1 minute protected String sid = ""; protected String secret = ""; protected String phone = ""; protected boolean initProperties; public Twilio() { } /** * Start sensing. */ @Override public void awake() { } /** * Load settings. */ public void initProperties() { if (this.initProperties) { return; } synchronized (this) { if (this.initProperties) { return; } getBot().memory().loadProperties("Twilio"); String property = this.bot.memory().getProperty("Twilio.sid"); if (property!= null) { this.sid = property; } property = this.bot.memory().getProperty("Twilio.secret"); if ((property!= null) && (this.sid!= null)) { this.secret = Utils.decrypt(Utils.KEY, property); } property = this.bot.memory().getProperty("Twilio.phone"); if (property!= null) { this.phone = property; } this.initProperties = true; } } public void saveProperties() { Network memory = getBot().memory().newMemory(); memory.saveProperty("Twilio.sid", this.sid, false); memory.saveProperty("Twilio.secret", Utils.encrypt(Utils.KEY, this.secret), false); memory.saveProperty("Twilio.

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the value of chest X-ray in detecting left ventricular (LV) size and function is still controversial, and it has been suggested that less than half of the patients with LV systolic dysfunction show a cardiothoracic ratio \>55%.\[[@ref6][@ref7]\] Although comparison with other techniques has shown only a weak correlation between cardiothoracic ratio and radionuclide, echocardiographic, or magnetic resonance imaging (MRI)-derived volumes and ejection fraction (EF),\[[@ref8][@ref9]\] heart size on the chest X-ray is still of considerable prognostic value in the patients with low LV ejection fraction (LVEF).\[[@ref10]--[@ref12]\] Moreover, the measurement of the transverse chest dimensions could represent a source of error in the evaluation of the cardiothoracic ratio, which is the parameter considered for the assessment of heart size in most of the studies published so far. An index derived from cardiac silhouette, which does not take into account measures of the chest, could therefore provide more reliable parameters for definition of LV dimension and function. Cardiac MRI -- due to its good accuracy and superior reproducibility -- is now considered as the Gold Standard for *in vivo* quantification of left and right ventricular volumes and EF.\[[@ref13]--[@ref18]\] MRI equipment, however, is not always available and its costs are considerable. On the other side, chest X-ray is fast, cheap, relatively safe in terms of radiation exposure, totally non-invasive, and is an easily available form of investigation. With these considerations in mind, the aim of this study was to evaluate in an unselected population undergoing cardiac MRI for clinical reasons the ability of a simple measurement derived from chest X-ray (transverse diameter of the heart shadow \[TDH\]) in detecting LV dilatation and systolic dysfunction, independently measured by cardiac MRI. MATERIALS AND METHODS {#sec1-2} ===================== Patients {#sec2-1} -------- A group of 101 consecutive patients admitted to our Institute and undergoing cardiac MRI and chest X-ray for clinical reasons were studied: 69 patients were males, mean age was 62±14 years. The indications for cardiac MRI were LV ischemic dysfunction, idiopathic cardiomyopathy, acute myo-pericarditis, valvular heart disease, hypertrophic cardiomyopathy, or arrhythmogenic right ventricular dysplasia in 50, 26, 6, 5, 2, and 12 patients, respectively. All patients were under stable clinical conditions at the time of the study. Chest radiography {#sec2-2} ----------------- Chest X-rays (postero-anterior and lateral projections), of patients in the erect position during an inspiratory breath-hold, with rib position on the 6^th^ rib anteriorly and the 10^th^ rib posteriorly, with focus-to-detector distance of approximately 2 m and very short exposure times, were analyzed. A digital system with Charged Coupled Device technology was used. The digital system IMIX-Thorax (Oy IMIX AB, Tampere, Finland), comprising a detector, scintillation camera, optical system, a system for converting X-ray photons, reconstructions computer, and post-processing computer, is capable of displaying the image in about 10 s. In the IMIX-Thorax, the detector system is strictly related to the ARCO COMB column (Arcoma AB, Vaxjo, Sweden). It includes an automatic exposure control system connected to the X-ray generator Medira 2064 (MEDIRA AB, Tampere, Finland), which ensures the constant and correct emission of radiation as a result of the automatic setting of the anode current at the X-ray tube. The chest X-rays were obtained within 2 days of the cardiac MRI study. The films were independently read by two expert radiologists who were blinded to the patient\'s clinical and functional status and level of severity of cardiac disease. For the analysis, a standardized reading grid was used. TDH was measured by drawing a line near the middle of the heart shadow and the spine with a line from the right heart border to that line. Another line from the left heart border farthest from the line in the middle of the heart shadow was added. The two lengths were added together to derive the transverse diameter of the heart \[[Figure 1](#F1){ref-type="fig"}\]. The cardiothoracic ratio (CTR) was also calculated as the ratio between the widest portion of the heart and the diameter of the chest, determined by drawing a line at the level of right leaf of the diaphragm and extending to the inner border of the rib cage on the right and on the left \[[Figure 1](#F1){ref-type="fig"}\]. ![Postero-anterior chest X-ray projection where the measure of the transverse diameter of heart shadow (TDH) is reported. The measure was taken by drawing a line near the middle of the heart shadow and the spine and a line from the right border to that line. Another line from the left heart border, drawn to the middle, was added. The two lengths were added together to derive the TDH.](JCIS-2-25-g002){#F1} Cardiac MRI {#sec2-3} ----------- Cardiac MRI was performed using a 1.5 Tesla whole body scanner (GE Medical Systems, Milwaukee, Wisconsin, USA). A 4-element cardiac phased-array receiver surface coil was utilized for signal reception. A breath-hold segmented-gradient fast-imaging echo, employing steady-state acquisition, triggered with the ECG, was used to evaluate global LV function according to standard parameters. In each patient, a total of 9-12 short-axis views (depending on the LV volumes) and 2 long-axis views (one vertical and one horizontal) were acquired, with a minimum of 30 cine frames for each slice. To measure LV volumes, the endocardial borders were manually drawn in all the short axis end-diastolic and end-systolic images, excluding papillary muscles. End-diastolic and end-systolic LV volumes were calculated and LVEF was derived.\[[@ref19]\] Cut-off values of LV end-diastolic volume (LVEDV) were calculated on the basis of normal values reported in our MRI lab.\[[@ref20]\] Therefore, an absolute LVEDV \>210 mL was considered as abnormal in males and \>150 mL as abnormal in females. The procedures followed were in accordance with the ethical standards of the Institutional Committee on Human Experimentation and with the Declaration of Helsinki of 1974, as revised in 2000. Approval of the Institutional Committee was obtained and each patient gave informed consent for undergoing clinical examination and chest X-ray after cardiac MRI. Statistical analysis {#sec2-4} -------------------- Quantitative data were expressed as mean ± standard deviation, qualitative data as percentage. The relationship between TDH and LV volume or LVEF at MRI was evaluated by least square linear regression analysis and the Pearson linear correlation (r). The cut-off value of the TDH utilized to identify volumes \>150 mL in females and \>210 mL in males was computed using the receiver operating characteristics (ROC) curve and Jouden\'s J. The performance indices of the cut-off value were used to determine sensitivity, specificity, positive and negative likelihood ratio (LR+, LR-), and the area under the ROC curve (AUC). The AUC was estimated by a non-parametric approach. The comparison between females and males for the AUC was made using the method for independent sample. Inter-observer reliability in chest X-ray measurements of two observers was evaluated using the correlation coefficient of Lin,\[[@ref21][@ref22]\] the intra-class correlation coefficient (ICC), and the Bland and Altman method.\[[@ref23]\] The ICC was calculated using a two-way random effects model where people and measure effects were random. A *P* value \<0.05 was considered to be statistically significant. All tests were two-tailed. The statistical analysis was made by JMP statistical software, SAS Institute Inc, version 4.0.0, and by Stata SE statistical software, StataCorp, release 10.\[[@ref24]\] RESULTS {#sec1-3} ======= Inter-observer variability {#sec2-5} -------------------------- The variability between the values of TDH measured by the two readers was very low. The correlation coefficient of Lin (r = 0,92, 95% C.I. = 0,87--0,97) and the intra-class correlation coefficient (ICC = 0,93, 95% C.I. = 0,86--0,96) were very high. The mean difference between readers was = 0.153 (s.d. = 0.572) and the Bland and Altman 95% Limits of Agreement were 1.275--0.969. As far as the inter-observer variability of thoracic dimensions, the correlation coefficient of Lin was 0,86 (95% C.I. = 0,77--0,95) and the intra-class correlation coefficient was 0,86 (95% C.I. = 0,65--0,94). The mean difference between readers was 0.900 (s.d. = 1.479) while the Bland and Altman 95% Limits of Agreement were -1.999--3.799. As far as CT ratio is concerned, the correlation coefficient of Lin was 0,84 (95% C.I. = 0,74--0,94) and the intra-class correlation coefficient was 0,84 (95% C.I. = 0,58--0,93). A mean difference between readers of -0.019 (s.d. = 0.029) and Bland and Altman 95% Limits of Agreement equal

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30's now - I still have a special place for a man that was willing to walk with me through the angst of adolescence. His Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-33160277391080212312012-10-22T14:13:00.001-07:002012-10-22T14:15:17.875-07:00Youth trust youth workers that trust themYou're not superman or wonder woman. At least I'm assuming that to be the case. Even if you were, I've read enough comic books to know that they have some seriously bad days. I do to. Traditionally the early fall is a bit back for us as we slowly get involved in the new pace of life of the students around us. This year however we have been given so many opportunities that we have hit the Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-85983234424679382322012-10-22T13:43:00.000-07:002012-10-22T13:43:01.977-07:00How thought has the power to save or destroy youthIn a recent discussion with a group of youth we talked to them about the power of thought. With the 60,000 plus thoughts that we generate each day, the overwhelming majority of them are negative. Which is not really a surprise to you as you read this. After all if you started cataloging all of your thoughts you would probably start to feel quite negative about yourself, the list you are Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-39373196446347484962012-10-22T13:19:00.001-07:002012-10-22T13:19:29.022-07:00How to think like a teenager. (not really).I have spent many years as a youth worker and before that I was a teen myself. I like to think that I am a relatable guy when it comes to youth issues. However, the only real experts are the youth themselves. To prove this point I recently asked a group of youth workers what the following youth culture slang meant, they didn't get any right. Lets see how you do: Is it a new product fromDanny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-76865380281695323582012-08-01T11:53:00.004-07:002012-08-01T11:59:24.279-07:00Choice: Hit the snooze or get out of bed! A young man questioned me the other day about purpose. He asked me, "Why do you get up in the morning?" I think at some point in our life, each of us must come to grips with a question like this. What is it that we live for? Life is hard. Life isn't fair. And to quote a scene from the TV series House: "Life is pain!" At some points it is easy to ignore. At some points you don't care.Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-71395423351795250342012-07-27T10:08:00.000-07:002012-07-27T10:08:02.342-07:00What to say when you are asked "Where was God?"One of the most difficult things I have experienced in working with young people is watching them fall. I can think of one young guy in particular who asked me when he was elementary school how he could be involved in our student leadership team. After telling him that he wasn't old enough to join that team he walked away disappointed. Years later I have remained in contact with him, only to Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-65780525925188043202012-03-08T14:52:00.001-08:002012-03-08T14:52:45.513-08:00Help a Youth Worker Out Hey, Some friends that work at a website called Chimp have extended an opportunity to me that I had to share with you. As you may or may not know, all of the youth work I do is funded by people, like you, that believe that young people need someone to walk along side them as they try to figure out life. Just in the past few months here are some examples of the types of situations I have Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-72105949645098651852012-01-19T16:49:00.000-08:002012-01-19T16:50:44.880-08:00Exploitation A Reality Of Surburban Youth WorkAs a youth worker, my job entails the opportunity to intersect into the lives of young people wherever they happen to be. I spend time on the streets, in the parks, the alleys, the movie theaters, schools and local coffee shops. Through this work I have encountered many things that I wish that I could unsee. This includes but is not limited to drug deals, suicide attempts, violent exchanges Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-74596806954547180512011-10-13T13:58:00.001-07:002011-10-13T21:05:10.830-07:00I was told, "Those kids are not worth your time." I responed, "thbbbbbb"If you have ever seen the movie, “Chariots of Fire” then you will remember the powerful line made by the Olympic Runner Eric Liddell struggling with his decision to take part in a competition being held on a Sunday, which was taboo in the Christian circles of his day. The quote goes like this: I believe God made me for a purpose, but he also made me fast. And when I run I feel His pleasure. Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-61839737968682181512011-09-27T11:08:00.000-07:002011-09-27T11:08:55.480-07:005 Ways To Go From Good Youth Worker To Great Youth WorkerI realized a long time ago that I do not have all the answers to being a great youth worker. There are so many other people that have traveled the path that are much better than I am. I am thankful for meeting people like Shae Pepper who has some suggestions for youth workers on what could move them from being good - to being great at what they do. Enjoy: I have met some good youth workers Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com1tag:blogger.com,1999:blog-8269847514852300861.post-86414864625755720382011-09-21T13:33:00.000-07:002011-09-21T13:33:32.982-07:00Book Review: Soul Survivor: How My Faith Survived The Church by Philip YanceyThe title of Philip Yancey’s book caught my eye. Soul Survivor: How My Faith Survived The ChurchThere are lots of things that frustrate me about the intuition of church. The politics.The religiosity.The people.What I was looking for were some answers to how to deal with these issues, what the book was about the people that shaped Yancey’s faith and theology. This was greatly encouraging as I Danny Fergusonhttp://www.blogger.com/profile/17626826438204735398noreply@blogger.com0tag:blogger.com,1999:blog-8269847514852300861.post-30391157242846864812011-09-19T14:55:00.000-07:002011-09-19T14:58:45.124-07:00Success in youth

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toujours gai how did you get the game leg mehitabel i asked her alas she said it is due to the treachery of one of these social swells who is sure one bad actor he was a fussed up cat with a bell around his neck on a ribbon and the look about him of a person that is currycombed and manicured from teeth to tail every day i met him down by the east river front when i was scouting about for a little piece of fish since the high cost of living has become so self conscious archy it would surprise you how close they watch their fish nowadays but what the h dash double l archy it is the cheerful heart that wins i am never cast down for long kid says this gilded feline to me you look hungry i am all of that i says to him i have a vacuum in my midst that is bigger than i am i could eat the fish that ate jonah kid he says you have seen better days i can tell that from looking at you thanks i said what you say is at least half true i have never seen any worse ones and so archy one word led to another until that sleek villain practically abducted me and i went with him on board a houseboat of which he was the pampered mascot such evidences of pomp and wealth archy were there that you would not believe them if i told of them to you poor cockroach that you are but these things were nothing to me for i am a reincarnation of cleopatra as i told you long ago you mean her soul transmigrated to a cat s body i said it is all one archy said she have it your own way reincarnation or transmigration is the same to me the point is i used to be a queen in egypt and will likely be one again this place was furnished swell percy i said the furniture is fine and i could eat some of it if i was a saw mill but where is the honest to g dash d food the eats percy what i crave is some cuisine for my stomach let us trifle with an open ice box for a space if one can be persuaded to divulge the scheme of its interior decoration follow me said this percy thing and led me to a cabin in which stood a table upon which stood viands i have heard of tables groaning archy but this one did not it was too satisfied it purred with contentment in an instant i had eaten a cold salmon who seemed to be toastmaster of the occasion and a whole scuttleful of chef doovers what you mean is hors douvres mehitabel i told her what i mean is grub said she when in walked a person whom i should judge to be either a butler or the admiral of that fleet or maybe both this percy creature who had led me to it was on the table eating with me what do you think he did what would any gentleman friend with a spark of chivalry do what but stand by a lady this percy does nothing of the kind archy he immediately attacks me do you get me archy he acts as if i was a stray cat he did not know and he was protecting his loving masters food from my onslaughts i do not doubt he got praise and had another blue ribbon for his heroism as for me i got the boot and as i went overboard they hit me on the limb with a bottle or an anchor or something nautical and hard that archy is why i limp but toujours gai archy what the h dash double l i am always merry and always ladylike mine archy has been a romantic life and i will tell you some more of my adventures ere long well au revoir i suppose i will have to go and start a pogrom against some poor innocent little mouse just the same i think that mehitabel s unsheltered life sometimes makes her a little sad # JULY 24 ## _Galoshes for Cockroaches_ do you know of any firm that specializes in galoshes for cockroaches it would be a graceful deed if you were to give me a pair for my birthday or a little motor boat would do i tried to get on the subway train to go up town the other day but a cascade caught me on the steps and carried me onto the tracks when i stopped floating i was in brooklyn # AUGUST 6 ## _A Poem in the Kipling Manner_ 1 "Where have you been so long? And what on earth do you mean by coming in here soused?" we asked Archy as he zigzagged from the door to the desk. He climbed onto the typewriter keys and replied indignantly: soused yourself i havent had a drink and yet i am elevated i admit it i have been down to a second hand book store eating a lot of kiplings earlier poetry it always excites me if i eat a dozen stanzas of it i get all lit up and i try to imitate it get out of my way now i feel a poem in the kipling manner taking me And before we could stop him he began to butt on the keys: the cockroach stood by the mickle wood in the flush of the astral dawn We interrupted. "Don't you mean Austral instead of astral?" Archy became angered and wrote peevishly: i wrote astral and i meant astral you let me be now i want to get this poem off my chest you are jealous if you were any kind of a sport at all you would fix this machine so i could write it in capitals it is a poem about a fight between a cockroach and a lot of other things get out of my way im off the cockroach stood by the mickle wood in the flush of the astral dawn and he sniffed the air from the hidden lair where the khyber swordfish spawn and the bilge and belch of the glutton welsh as they smelted their warlock cheese surged to and fro where the grinding floe wrenched at the headlands knees half seas over under up again and the barnacles white in the moon the pole stars chasing its tail like a pup again and the dish ran away with the spoon the waterspout came bellowing out of the red horizons rim and the grey typhoon and the black monsoon surged forth to the fight with him with three fold might they surged to the fight for they hated the great bull roach and they cried begod as they lashed the sod and here is an egg to poach we will bash his mug with his own raw lug new stripped from off his dome for there is no law but teeth and claw to the nor nor east of nome the punjab gull shall have his skull ere he goes to the burning ghaut for there is no time for aught but crime where the jungle lore is taught across the dark the afghan shark is whining for his head there shall be no rule but death and dule till the deep red maws are fed half seas under up and down again and her keel was blown off in a squall girls we misdoubt that we ll ever see town again haul boys haul boys haul. "Archy," we interrupted, "that haul, boys, is all right to the eye, but the ear will surely make it hall boys. Better change it." you are jealous you let me alone im off again the cockroach spat and he tilted his hat and he grinned through the lowering mirk the cockroach felt in his rangoon belt for his good bengali dirk he reefed his mast against the blast and he bent his mizzen free and he pointed the cleats of his bin nacle sheets at the teeth of the

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the cannabis sector of hostile consolidation transactions with companies using their stock as currency. To protect shareholders from such coercive activity, Origin House recently announced the signing of voluntary voting support agreements. Read the full news release Q. Do you see your position as middle-men between growers and retailers to be a limited and possibly temporary strategy as compared to vertically integrated businesses? Our business strategy goes beyond being a middle-man between growers and retailers. We are laser-focused on building a strong foundation based on a unique strategy that will position Origin House to be the leading global house of brands. We’ve already built a strong framework that consists of manufacturing, distribution, logistics capabilities and added talented people to our team to ensure success for our brand partners. We will progressively internalize authentic brands and accelerate growth, replicating the blueprint in new markets. Stay tuned for more, in 2019! Q. With many US states legalizing cannabis, does Origin House have a current plan in place to enter into other states with the same approach that has made it possible to acquire the dominant position it holds in California? We are always There is a growing trend within the cannabis sector of hostile consolidation transactions with companies using their stock as currency. To protect shareholders from such coercive activity, Origin House recently announced the signing of voluntary voting support agreements. Read the full news release here Our business strategy goes beyond being a middle-man between growers and retailers. We are laser-focused on building a strong foundation based on a unique strategy that will position Origin House to be the leading global house of brands. We’ve already built a strong framework that consists of manufacturing, distribution, logistics capabilities and added talented people to our team to ensure success for our brand partners. We will progressively internalize authentic brands and accelerate growth, replicating the blueprint in new markets. Stay tuned for more, in 2019!We are always looking and exploring new markets, but we will enter when it makes business sense for us to do so. We’re keeping a keen eye open and when the regulations change and permit us to trade on other exchange, we will explore the opportunity Q. How does the Ontario government’s decision to allow only 25 cannabis stores impact your plans for 180 Smoke? 180 Smoke already has strong retail capabilities for the expanding nicotine vape e-juice manufacturing and cannabis hardware business which generated $11.7 million in net revenue in 2018, up 50% from $7.8 million in 2017. The limitation of 25 licenses does not impact our plans for 180 Smoke. We will continue to expand our footprint and as the Canadian cannabis landscape continues to evolve, we look forward to adding cannabis retail to our 180 portfolio.# Elixir Python definitions for qemu exec(open('commonkconfig.py').read()) Q: Bundle unable to locate/execute gems for ruby app if installed through Chef I am trying to deploy a ruby app through chef. I have installed ruby and rubygems through rvm. When I do a bundle install --deployment manually on the shell I get all the bundles downloaded to vendor/bundle location and everything works fine. But when I do the same with chef using bash resource I get error messages mentioned below. I feel like some issue with the PATH or environmental variables. Through chef also it downloads all the gems but when I open the shell and check I get errors. Please note - chef recipes executes without any errors. *bundle exec rake db:create RAILS_ENV=production (in /home/xyz) rake aborted! undefined method `[]' for nil:NilClass /home/xyz/Rakefile:4:in `require' (See full trace by running task with --trace)* # ruby -v ruby 1.9.2p290 (2011-07-09 revision 32553) [x86_64-linux] # gem -v 1.8.1 bundle -v Bundler version 1.0.15 # gem env RubyGems Environment: - RUBYGEMS VERSION: 1.8.1 - RUBY VERSION: 1.9.2 (2011-07-09 patchlevel 290) [x86_64-linux] - INSTALLATION DIRECTORY: /usr/local/rvm/gems/ruby-1.9.2-p290 - RUBY EXECUTABLE: /usr/local/rvm/rubies/ruby-1.9.2-p290/bin/ruby - EXECUTABLE DIRECTORY: /usr/local/rvm/gems/ruby-1.9.2-p290/bin - RUBYGEMS PLATFORMS: - ruby - x86_64-linux - GEM PATHS: - /usr/local/rvm/gems/ruby-1.9.2-p290 - /usr/local/rvm/gems/ruby-1.9.2-p290@global - GEM CONFIGURATION: - :update_sources => true - :verbose => true - :benchmark => false - :backtrace => false - :bulk_threshold => 1000 - REMOTE SOURCES: - http://rubygems.org/ bash "bundle install" do user "root" cwd "/home/xyz/" code <<-EOH source /etc/profile.d/rvm.sh rvm use 1.9.2-p290 --default /usr/local/rvm/gems/ruby-1.9.2-p290/bin/bundle install --path vendor/bundle /usr/local/rvm/gems/ruby-1.9.2-p290/bin/bundle exec rake db:create RAILS_ENV=production EOH end This is the first time I am deploying any ruby app, I have googled a lot and tried many solutions but I get more and more errors but no solutions. Any kind of help would be greatly appreciated. Thanks, Imran A: So I believe the reason why you are having some issues with ruby installed by RVM has to do with the nature of linux + shells. RVM masks a lot complexity underneath when it presents you with a list of ruby builds that you can install on your system. Simple answer is RVM ( similar to rbenv ) works by hooking into your environment's PATH... This is a very detailed explanation provided by Sam Stephenson here: How do RVM and rbenv actually work? but I digress. My guess is that your RVM installation is made for an individual user, eg user who has home directory /home/xyz/. At this point, I think your problem is the following: You installed RVM via Single-User installation( Details here: https://rvm.io/rvm/install ). When you installed RVM, they probably made you do this step here: echo "source $HOME/.rvm/scripts/rvm" >> ~/.bash_profile. This step adds a command into your.bash_profile so that on each new session/terminal window, your user ( in this case, user xyz ) reads in information on how to run/use RVM. The bash resource in chef isn't actually using the same shell that you use to connect and run commands. My thought is that, if you run something like: bash 'install_ruby_stuff' do cwd ::File.dirname(/home/xyz) code <<-EOH source /home/xyz/.rvm/scripts/rvm bundle exec rake db:create RAILS_ENV=production EOH end I have a feeling it might work a bit better. If that doesn't work, run which bundle and figure out exactly where rvm installs the bin stub for the bundle command, then replace bundle above, with /path/to/bundle and that might help as well. Each bash resource call in chef is essentially treated like a separate shell, so any PATH or ENV variables that you need, need to be defined within the same context that the bash resource is called. Hope this helps you a bit! The extraction of critical events relevant to a broadcast sporting event is a manual and time-consuming task. This is typically performed by video annotators who view a recording of the event and manually scrub through the video to annotate the video in order to break the video into segments for future use. Time codes embedded in the video are typically used as the mode of identifying the segment of the video that is relevant. Accordingly, the ability to extract these types of data and synchronize with video is a challenge. Sporting activities contain repeating events of fine granularity, such as clocks and timers, which are independent of the play action, as well as events that are dependent on the action of the players. One currently used broadcast methodology for enhancing the fan experience is to embed this data by rendering a graphical representation of it into the video program. For example, an on-screen dashboard typically shows information such as scores, game-clocks, shot-clocks, etc. Recently, there has been an increase in the amount of data that is being displayed in these on-screen dashboards. A further methodology sends out-of-band data for the sporting event. However, the transmission path for the out

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value (231 mM^−1^s^−1^) than Z-Lys-Lys-AMC, which seems to be due to a decrease in *K*~m~. Noteworthy, the introduction of the PABA linker was not tolerated by cathepsin L as the analog of **19** containing Phe instead of Lys in P^2^ (Z-Phe-Lys-PABA-AMC) was not converted by this enzyme. Therefore, the combination of the two Lys residues with the self-destructive PABA linker makes **19** to a substrate which is cleaved by cathepsin B with excellent selectivity over cathepsins L and S. Probe **19** was also effectively cleaved by lysates of HeLa cervical tumor cells. Pretreatment of HeLa cells by the cell-permeable pro-inhibitors E64d (**8b**) or CA074Me (**9b**), which inhibit several cysteine cathepsins or selectively cathepsin B, respectively, after intracellular activation by esterases, resulted in a complete blocking of the conversion of **19**. Fluorescence microscopic observation of live HeLa cells in the presence of Z-Arg-Arg-AMC or Z-Phe-Arg-AMC did not result in the detection of any cellular fluorescence. Contrary to this, the three-component probe **19** containing the PABA linker led to blue fluorescent cells, while no intracellular fluorescence could be visualized in the presence of CA074Me (**9b**) or E64d (**8b**). Similar results were obtained when the HeLa cells were replaced by the Her2-positive breast cancer cell line MDA-MB-231-H2N. These results clearly indicate that **19** undergoes cathepsin B-dependent activation inside the cells and that the PABA linker obviously facilitates membrane permeation of the peptidic probe. When Z-Phe-Lys-PABA-AMC was investigated in the same manner, it was revealed that its cellular activation was only completely blocked by treatment with E64d, while the presence of CA074Me resulted in considerable residual cellular fluorescence. These observations suggest that the latter probe is activated by cathepsin B and other cysteine cathepsins, which is in accordance to results from kinetic investigations and cell lysate experiments. Furthermore, Z-Phe-Lys-PABA-AMC compromises cell viability in both cell lines as assessed by the MTT assay, while **19** and the ordinary two-component probe Z-Arg-Arg-AMC are well-tolerated (Chowdhury et al., [@B44]). ![**Fluorogenic substrate-based probes for targeting of cysteine cathepsins containing only one luminophor**. Emitting fluorophoric moieties are shown in red, moieties that act as spacer are highlighted in green and additional targeting moieties are shown in blue.](fchem-03-00037-g0008){#F8} While 7-amino-4-methylcoumarin is an advantageous fluorophore for protease activatable probes due to its small size, its blue fluorescence and rather short excitation wavelength are adverse properties. Alternatives can be found by rhodamine derivatives, which exhibit two amino groups attached to the xanthenyl system and offer the opportunity of longer wavelength excitation/emission together with high quantum yields for fluorescence. Peptidic moieties can be attached to the two amino groups of rhodamines which will result in fluorescence attenuation and illumination upon protease-mediated cleavage (Leytus et al., [@B127]; Rothe et al., [@B187]). However, a drawback of such probes is that consecutive removal of two peptide residues will result in mono-acylated and completely deacylated rhodamine species which will differ in their fluorescence properties. To tackle that problem, Fujii et al. ([@B76]) developed activatable probes based on "reduced" rhodamine green (rhodamine green is also known as rhodamine 110), in which the carboxy group is replaced by a hydroxymethyl residue. Typical for xanthene dyes, this hydroxymethyl rhodamine green (HMRG) exists in solution in a ring-chain tautomeric equilibrium between a non-fluorescent spirocyclic form and a highly fluorescent quinoid open form. At physiological pH, the equilibrium lies on the side of the open form, which is characterized by favorable photophysical properties such as high fluorescence quantum yield (Φ~fl~ = 0.81) and long fluorescence lifetime (τ = 3.8 ns) (Sakabe et al., [@B198]). Mono-acylation of one of the amino groups will stabilize the non-fluorescent spirocyclic form and thus result in strong attenuation of fluorescence. Fujii et al. aimed to exploit this principle for the design of cathepsin B-activatable probes in the context of optical tumor imaging. To this end, they attached the Z-Phe-Arg (as realized in compound **20**) and Z-Arg-Arg moiety to HMRG. The extinction coefficient of free HMRG is more than 400 times higher than that of **20** (at λ~max~ = 501 and 497 nm, respectively). The kinetic evaluation toward the cathepsins L, B, S and K was done at pH 5.5 and pH 7.4, to simulate intralysosomal and cytosolic/extracellular pH-values, at a single substrate concentration of 3 μM. Cathepsin B rapidly converted **20** at both pH-values, whereas the cleavage of Z-Arg-Arg-HMRG was only effective at pH 5.5. At this pH conversion of **20** by cathepsin L was slower than that by B, whereas Z-Arg-Arg-HMRG was cleaved with much lower velocity. The cleavage of **20** catalyzed by cathepsin L at pH 7.4 was very slow, probably due to the fact that cathepsin L undergoes irreversible inactivation at pH-values greater than 6.5 (Brömme et al., [@B31]). Compound **20** was also converted by cathepsin K at both pH-values but was no effective substrate of cathepsin S. Incubation of **20** with SK-OV-3 human ovarian tumor cells resulted in microscopically visible cell-associated fluorescence, which was attenuable by treatment with the broad-spectrum cell-permeable fluoromethylketone inhibitior Z-Phe-Phe-FMK (**1a**). It was concluded that cleavage of **20** occurs intracellularly, because the treatment with membrane-impermeable inhibitor CA074 (**9a**) was of negligible influence. Intraperitoneal injection of **20** into mice bearing peritoneally implanted SK-OV-3 tumors, a model for human ovarian cancer, resulted in a clear visualization of the tumor nodules with a tumor-to-background ratio of 4.2 The stability of **20** in peritoneal liquid has been confirmed independently and the green HMRG fluorescence colocalized with the tumor nodules when SK-OV-3 cells transformed with red fluorescent protein (RFP) were implanted. The disadvantages of the discussed non-quenched cathepsin-responsive probes are due to the fact that the emission wavelengths of their fluorophores are too short for *in vivo* imaging. Fluorophores with emission wavelengths in the near infrared (NIR) range can be found within the class of cyanine dyes, which are employed in the FRET-based probes **16** and **17** discussed above. Despite these fluorophores are characterized by high extinction coefficients, acylation-based attenuation of fluorescence is difficult to realize, in contrast to luminescent groups on the basis of aromatic amines such as AMC and HMRG. To overcome this drawback, Kisin-Finfer and Shabat ([@B114]) set out to develop fluorophores where three consecutive carbons of the polymethine chain of cyanine dyes are part of a napthalene ring. To this end, they reacted 4-hydroxynaphthalene-1,3-dicarbaldehyde with two equivalents of 3-(2,3,3-trimethyl-3H-indol-1-ium-1-yl)propane-1-sulfonate in a Knoevenagel-type condensation. The obtained product is a representative of the so called "donor-two-acceptor" NIR dyes, referring to the electron-donating hydroxyl group and the two indolium acceptor moieties (Karton-Lifshin et al., [@B105]), and shows a pH-dependent fluorescence with an emission wavelength of 740 nm and a large Stokes shift of 80 nm. Notably, only the deprotonated phenolate form is fluorescent. In consequence, acylation of the OH group will lead to strongly attenuated fluorescence, which can be exploited to design hydrolase-sensitive probes as it has been realized in compound **21** for imaging of cathepsin B (Kisin-Finfer et al., [@B113]). Considering the steric demand of the fluorophore, its conjugation to the cathepsin-responsive Z-Phe-Lys moiety was done via a self-immolative linker which resembles in part the PABA linker contained in **19** (Chowdhury et al., [@B44]). In difference, a *N*,*N*\'-dimethylethylenediamine-carbonyl spacer follows the PABA element (Shabat et al., [@B212]). Analogously to **19**, cathepsin B-mediated release of the aromatic amine will result in the formation of imino quinone methide and carbon dioxide. This reaction step triggers in turn the release of the phenolic hydroxyl group via cyclisation by attack of the secondary amine nitrogen to the carbamate carbon under concomitant formation of a five-membered cyclic urea. Apart from creating space between the fluorophore and the cleavage site, this strategy ensures that the two functional entities

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ill(); } if (document.arrive && this.options.arrive) { if ($.fn.ripples && this.options.ripples) { $(document).arrive(this.options.withRipples, function() { $.material.ripples($(this)); }); } if (this.options.input) { $(document).arrive(this.options.inputElements, function() { $.material.input($(this)); }); } if (this.options.checkbox) { $(document).arrive(this.options.checkboxElements, function() { $.material.checkbox($(this)); }); } if (this.options.radio) { $(document).arrive(this.options.radioElements, function() { $.material.radio($(this)); }); } if (this.options.togglebutton) { $(document).arrive(this.options.togglebuttonElements, function() { $.material.togglebutton($(this)); }); } } } }; })(jQuery); Raymond Scholwinski might have caught the coronavirus on March 16, his wife Rynda Scholwinski believes, but there's no telling for sure. On that day, the 70-year-old Harris County Sheriff’s sergeant met with a deputy who later tested positive for COVID-19, the disease caused by the coronavirus. The fever arrived a few days later - low. Fatigue. But such symptoms weren’t unusual for Scholwinski, who has scarred lungs that make him cough sometimes. But days later, he still had a fever. “We had some high hopes,” Rynda said. “But that evening, his fever came back up.” Now, her husband is fighting for his life in a bed in an ICU at Memorial Hermann’s hospital in the Woodlands. He is one of thousands of first responders sickened by COVID-19 nationally, including dozens in Harris County. Police families know the inherent dangers in their jobs - car crashes, fights with suspects, getting shot - but the coronavirus is different. Just going to work means walking into the line of fire of an unseen enemy. So far, 30 Harris County deputies have become ill, and the number will grow. “We have the same caution and fears as the general public, except we don’t have the option to stay home,” said Harris County Deputies’ Organization President David Cuevas. “We have to go to work, continuously do our job and we’re fighting an enemy we can’t see.” Deputies also still have to run the county jail, a crowded facility holding more than 7,500 inmates in close proximity. Experts fear an outbreak tearing through the jail. A dozen jail employees have already come down with the virus. Three inmates have tested positive; dozens more are presumed ill, and 850 others are in quarantine after possible exposure. “It’s challenging for our personnel,” Sheriff Ed Gonzalez said. “And the anxiety …. They’re seeing teammates become ill, seeing that a number of first responders are starting to die around the country. It’s all very new and scary to us.” RELATED: First responders can’t social distance. Some are getting sick. And departments say it could strain responses A caretaker Rynda also fell ill - and had to spend four days in bed. Even getting up to let Cissy, her Yorkie, outside exhausted her. Raymond brought her water, and Gatorade. “He always took care of me,” she said. It has been that way ever since they first met 35 years ago, when he was working at the apartment complex where she lived and slowly began courting her. Lean and gregarious, he seemed to know everyone. He’d retired from the insulation installation business he’d created and was working at several apartment building. But his heart was at the sheriff’s office. When she cut her hand on shattered glass, and needed surgery, he drove her to and from the appointment. He brought her meals, and flowers. She thought he was taking pity on her. He had other plans. On a camping trip a year after they met, he asked her to marry him. By then, she’d long since fallen for him, for the way he always looked out for her, and the way he always tried to help out the elderly residents in the complex where she lived. On his days off, he sometimes worked at the marine division of the sheriff’s office, where he’d volunteered as a reserve deputy in 1979. He decided to work there full-time soon after they married. It was nerve-wracking for her. When he worked nights, she always woke up early, looking for him on the morning news being interviewed from a crime scene. If he was on TV, that meant he hadn’t got hurt. This feels different. “They go through training how to learn how to approach a vehicle to make a stop, how to answer a door when they’re going to a domestic violence call” she said. “But you can’t even train against this.” Scholwinski works at the sheriff’s office’s station in District 2, where he helps run public safety town halls with residents. He works long hours, helping frustrated residents and attending community meetings, his District 2 colleagues said. “He loves people. That’s why he loves this job,” District 2 Capt. Mike Koteras said. RELATED: From swing sets to adult novelty shops, 311 calls report social distancing violators in Houston area His colleagues describe him as the go-to guy when there’s a problem. He’s the one on his hands and knees helping friends fix a broke-down car, or pulling out his wallet to help, whether he can afford it or not. The one who shows up hours early to cook turkeys for deputies working on Thanksgiving, and then stays hours late cleaning up. “He’s got time for everybody,” said Sgt. Joe Halm. “No matter if he’s in a hurry, he’ll stop, he will talk to people.” Now his friends and fellow deputies are watching, stunned, as he fights for his life. Test results After Scholwinski started to feel sick he drove to Baytown to get tested. The result came back positive. Rynda tested positive a few days later. They were encouraged at first, even as they both battled mild fevers and fatigue. Rynda counted the days. Each day was an emotional roller coaster, fevers rising, then breaking. They prayed, and tried to stay positive. “The longer it got, the more hopeful I became it wouldn’t get into his lungs,” she said. “But I was very wrong about that.” His fever, in spikes, inexorably ticked upward. “We were yo-yos,” Scholwinski said. THE FIRST FIFTY: What we can learn from the Houston-area people first diagnosed with COVID-19 On Sunday, March 29, breathing became more difficult. They called his pulmonologist, who told them to head to the hospital. They drove from their home in Inverness Forest to the hospital later that morning, holding hands along the way. When she stepped out of her Denali, she told the waiting nurses they both were sick with COVID-19. Her mask muffled her voice, and so she took a step closer to the nurses, so they could hear her better. They waved her back. A nurse went inside, and brought out identity bracelets for Scholwinski -- and a wheelchair. A nurse eased Raymond into it, and warned Rynda that because of the virus, she wouldn’t be able to visit. She watched as they began wheeling him toward the hospital doors. She told him she loved him. To fight with all his might. To hurry home. He told her he loved her, and that he would do his best. Then the doors shut behind him. “That’s the last time I saw him,” she said, her voice catching. After Scholwinski arrived at the hospital, doctors started giving him oxygen, Rynda said. Doctors prescribed hydroxychloroquine, the medicine President Donald Trump has touted. By the next day, doctors told Rynda that Raymond wasn’t responding to the medication anymore. The couple tried to talk every day, but she did most of the speaking. On Thursday, doctors called. Raymond needed to go on a ventilator, a potentially life-saving intervention, but one that often signals a rapid decline. Rynda’s mind raced. She wondered what it would mean for her husband. “Every little step he takes backwards means it’s that many more before he can step forward,” she said. On Tuesday, Scholwinski remained in an artificially induced coma, on dialysis. The virus has made it difficult for his body to expel the carbon dioxide it produces, so the machine is helping pull the gas from his blood. “He’s hanging in there,” Rynda said. “He has a lot to

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some thirty thousand soldiers were sentenced to death, with perhaps twenty thousand of those executed, most in the last year or so of the war, as against forty-eight executed in all the German armed forces during World War I. If National Socialist ideas failed to inspire a will to resist, then Nazi terror would be used instead. For the average soldier, the war had become, in the most concrete sense, a battle for survival. With the Germans driven back across the Dnieper, the Red Army had attained the original goal of its summer offensive but now moved to exploit the fruits of its victory. Drawing on the local population for replacements--some eighty thousand men were drafted from the liberated areas and thrown into the battle--and concerned that, if given time, the Germans would take advantage of the river line to stalemate the war, the Soviets bounced the river in a number of places and established bridgeheads on the west bank as launching pads for future operations. Although the Dnieper, with its broad channel, high bluffs on the western side, and swampy eastern bank, afforded the strongest natural defensive line in western Russia, Hitler's stubborn insistence on holding out east of the river had deprived the Germans of most of its advantages. Not only had their strength been sapped, but work on constructing defenses along the river had also lagged. Many Landsers, encouraged by the talk of an Ostwall, were dismayed to find on crossing the river that little had been built and they were left in the open. "We had expected," wrote one, "to find the Ostwall behind the Dnieper. Not even trenches were there." This shock to the morale of the exhausted German forces was compounded by the awareness of the vast mismatch in strength between the opposing sides. Although on paper Manstein had sixty divisions at his disposal, in reality most had the strength only of a regiment and some not even of a _Kampfgruppe_ (battle group). In early October, Army Group South had only about one thousand combat troops per division, fewer than three hundred operational tanks and assault guns, and not quite six hundred aircraft for itself and Army Group A to its south. Manstein himself admitted gloomily at the end of October that the combat strength of his troops, exhausted by ceaseless battle for months, had "sunk so low... that as a result of our insufficient manpower in the front lines the enemy can punch through anywhere he assembles sufficient forces." Instead of organizing a defense along the river line, however, he had to try, with inadequate forces, to eliminate or contain the numerous Soviet bridgeheads, even as the enemy sought to exploit its vast numerical preponderance by launching several attacks simultaneously along the front. Of these bridgeheads, the ones ultimately most dangerous were north of Kiev at Liutezh and Chernobyl. The Red Army had originally hoped, in a daring blow using massed armor and airborne troops, to burst out of the Bukrin bridgehead to the south of the Ukrainian capital in late September and seize the city in a sweeping move to the west and north. Although this had resulted in a fiasco, Vatutin skillfully moved his troops, under cover of effective camouflage measures, to the northern bridgeheads. Following a massive artillery barrage, Soviet forces on 3 November assaulted the thin German defenses at Liutezh, at the same time breaking out of the bridgehead near Chernobyl. Within two days, the Fourth Panzer Army front had been shattered, and, lacking reserves of any kind, it was helpless to slow the enemy advance. By the sixth, Kiev had fallen, and Soviet forces were pushing westward almost unhindered. Troops of the First Ukrainian Front, storming out of the Chernobyl bridgehead, raced toward the city of Korosten at the border of Army Groups Center and South, having blasted a sixty-mile-wide gap between the two army groups just south of the Pripet Marshes, a no-man's-land that the Germans could cover only with reconnaissance troops and patrols. Although the giant swamps of the Pripet offered the Second Army to the north some flank protection, it was primarily controlled by partisan bands, which left the danger that the Soviets might be able to roll up the soft underbelly of the Second Army from the south. Fortunately for the Germans, the various Soviet, Ukrainian, and Polish partisans operating in the Pripet fought each other as much as the German occupier, so an immediate threat failed to materialize, but the situation remained unstable. More pressing was the danger from Red Army troops driving out of Liutezh on the key railroad junction of Fastov, thirty miles southwest of Kiev, which controlled the lines supplying Army Group South's central sector. Its fall on the seventh raised the possibility that the army group might be enveloped, especially since the southern wing of the front had been under assault since early October. With his efforts to repair the situation on the northern end of his sector frustrated by Hitler's insistence on defending the great bend of the Dnieper to the south, Manstein flew to Fuhrer Headquarters on the ninth to demand its evacuation, a move that would shorten the front considerably and free units for use in the north. To Manstein, there seemed little operational point to holding on to the Dnieper bend, especially since Zaporozhye and Dnepropetrovsk had already been lost in mid-October. In addition, Soviet troops had shattered the front of the Sixth Army (Army Group A) at Melitopol on 23 October and reached the Black Sea in early November, trapping the Seventeenth Army in the Crimea. As always, however, Hitler insisted that the manganese ore mines near Nikopol could not be given up without great harm to the armaments effort, nor could the Crimea be abandoned since it would provide the Soviets airfields from which to attack the vital Rumanian oil fields. Ironically, the Fuhrer's intransigence had been reinforced late in October by Manstein himself. In expectation of receiving five fresh panzer divisions from the west, the OKW having decided that the danger of an Allied invasion had passed, he proposed an attack, reminiscent of his Kharkov success, to cut off the exposed Soviet forces. By now, however, the urgent danger in the north had pushed aside all thoughts of such an operation, but neither the field marshal nor Gehlen, who warned of a "collapse of the eastern front," proved able to change Hitler's mind. It was, he said, a risk that would have to be taken, although he did allow Manstein to use some of the newly arrived panzer divisions in the area of the Fourth Panzer Army. One of these was the newly raised Twenty-fifth Panzer Division, just arrived from France after a series of misadventures that had seen it originally sent to the right flank of the army group before being hurried north, with the result that its equipment was scattered over hundreds of miles. Although not trained for fighting on the eastern front, and lacking much of its heavy weapons--it was, as one author noted ironically, a panzer division without panzers--it was the only unit available to slow the Soviet advance at Fastov. Against Guderian's vehement objections, the Twenty-fifth Panzer, with as much strength as it could muster, was thrown on the seventh into a counterattack at Fastov in an attempt to regain the rail juncture. By the time its full complement of armored vehicles arrived two days later, it had already suffered such losses that it was unable to retake the city, an outcome that sent Hitler into a rage. More importantly, in throwing into battle a unit clearly unready for combat, the German leadership had departed from its key principle. In contrast to the Soviets, who had squandered many newly formed divisions by throwing them prematurely into combat, the Germans had allowed units to train behind the front to gain experience before being sent into battle. Still, despite being sacrificed, the Twenty-fifth Panzer had performed a vital task: it had slowed the Soviet advance at Fastov and gave Manstein time to organize a counterattack. Launched on 15 November, the counterstrike was carried out by General Hermann Balck's Forty-eighth Panzer Corps, which had assembled almost three hundred armored vehicles. Typically at this stage, since the Germans had not yet completely abandoned the idea of regaining the initiative, it aimed at not just pinching off the Soviet advance but ultimately recapturing Kiev. By the twenty-third, Balck's forces had retaken both Brusilov and Zhitomir, while, to the north, German troops had beaten off an enemy attack at Korosten, regaining the city on the twenty-seventh. Manstein now planned a strike directly east toward Kiev, but several days of steady rain turned the roads into muddy quagmires, forcing a halt to the operation. After the ground had frozen, the Germans renewed their assault on 6 December, with the two hundred armored vehicles of the Forty-eighth Panzer Corps assailing nine Soviet armies, among them two full tank armies and a tank corps. Amazingly, in view of the overwhelming enemy superiority, Balck's men achieved a few local victories, recapturing Radomsyl on the sixteenth, and generally spreading anxiety and consternation in the Soviet rear. Still, these local triumphs only confirmed the larger German dilemma. Although they proved time and again tactically superior to the Soviets, the Germans could not convert these local victories into an operational breakthrough because at the crucial moment they lacked the necessary strength. Thus, although between August and December in all operations against Army Group South alone the Soviets suffered the staggering total of 417,323

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gamma}|_{[s_{1}, s_{2}]}) = s_{2} - s_{1} = \left| \int_{\tilde{x}(s_1)}^{\tilde{x}(s_2)} \frac{m(t)}{\sqrt{m(t)^{2} -\nu^2}}\,dt \right|_.$$ Since $\tilde{x}'(s) \not= 0$ for all $s \in (s_{1}, s_{2})$ with $\tilde{x}(s) \in [t_{1}, t_{2}]$, we may choose the numbers $s_{1}$ and $s_{2}$ in such a way that $$\tilde{x}(s_{1}) = t_{1}, \quad \tilde{x}(s_{2}) = t_{2}$$ or $$\tilde{x}(s_{1}) = t_{2}, \quad \tilde{x}(s_{2}) = t_{1}.$$ Thus, we see that $$\label{lem6.3-1} { L(\tilde{\gamma}) \ge \int_{t_{1}}^{t_{2}} \frac{m(t)}{\sqrt{m(t)^{2} -\nu^2}}\,dt }_.$$ Since $${ \frac{m(t)}{\sqrt{m(t)^{2} -\nu^2}} \ge 1 + \frac{\nu^{2}}{ 2 m(t) \sqrt{m(t)^{2} -\nu^2} } }_,$$ we have, by (\[lem6.3-1\]), $${ L(\tilde{\gamma}) \ge t_{2} - t_{1} + \frac{\nu^{2}}{2} \int_{t_{1}}^{t_{2}} \frac{1}{m(t)\sqrt{m(t)^{2} -\nu^{2}}}\,dt }_.$$ ${\hfill \Box}$ \[lem2009-03-03\] For any $q \in \Cut (\partial X) \cap (X \setminus \partial X)$ and any ${\varepsilon}> 0$, there exists a point in $\Cut (\partial X) \cap B_{{\varepsilon}} (q)$ which admits at least two $\partial X$-segments. The above lemma is well-known in the case of the cut locus of a point (see [@B]), which can be proved similarly. However we will give a proof of the lemma totally different from it (see Section \[sec:appe\]). \[prop6.4\] Let $\mu_{0} :[0, \infty) {\longrightarrow}X$ be a $\partial X$-ray guaranteed by the assumption above. If $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies $$\label{prop6.4-con1} { \int_{0}^{\infty} \frac{1}{m (t)^{2}}dt = \infty }_,$$ or $$\label{prop6.4-con2} { \liminf_{t \to \infty} m(t) = 0 }_,$$ then, any point of $X$ lies in a unique $\partial X$-ray. In particular, $\partial X$ is totally geodesic in the case where (\[prop6.4-con1\]) is satisfied. Choose any point $q \in X \setminus \partial X$ not lying on $\mu_{0}$. Let $\mu_{1} : [0, d(\partial X, q)] {\longrightarrow}X$ denote a $\partial X$-segment with $\mu_{1} (d(\partial X, q)) = q$. For each $t > 0$, let $\gamma_{t} :[0, d(q, \mu_{0}(t))]{\longrightarrow}X$ denote a minimal geodesic segment emanating from $q$ to $\mu_{0} (t)$. From Proposition \[weak\] and the triangle inequality, it follows that there exists a generalized open triangle $(\partial {\widetilde}{X}, {\widehat}{\mu}_{0}(t), {\widehat}{q}\,) = ({\widehat}{\gamma}_{t}, {\widehat}{\mu}_{0}^{(t)}, {\widehat}{\mu}_{1})$ in ${\widetilde}{X}$ corresponding to the triangle $(\partial X, \mu_{0}(t), q) = (\gamma_{t}, \mu_{0}|_{[0, \,t]}, \mu_{1})$ in $X$ such that $$\label{prop6.4-length1} d(\partial {\widetilde}{X}, {\widehat}{\mu}_{0}(t)) = t, \quad d(\partial {\widetilde}{X},{\widehat}{q}\,) = d(\partial X, q),$$ and $$\label{prop6.4-length2} L(\,{\widehat}{\gamma}_{t}\,) \le d(\mu_{0}(t), q) \le t + d(q, \mu_{0}(0))$$ and that $$\label{prop6.4-angle} \angle(\partial X, q, \mu_{0} (t)) \ge \angle(\partial {\widetilde}{X}, {\widehat}{q}, {\widehat}{\mu}_{0} (t)).$$ Here $\angle(\partial X, q, \mu_{0} (t))$ denotes the angle between two sides $\mu_{1}$ and $\gamma_{t}$ joining $q$ to $\partial X$ and $\mu_{0} (t)$ forming the triangle $(\partial X, \mu_{0}(t), q)$. From Lemma \[lem6.3\], (\[prop6.4-length1\]), and (\[prop6.4-length2\]), we get $$\begin{aligned} \label{prop6.4-1} t + d(q, \mu_{0}(0)) &\ge L(\,{\widehat}{\gamma}_{t}\,)\notag\\[2mm] &\ge { t - d(\partial X, q) + \frac{\nu_{t}^{2}}{2} \int_{d(\partial X,\, q)}^{t} \frac{1}{m(t)\sqrt{m(t)^{2} -\nu_{t}^{2}}}\,dt }_.\end{aligned}$$ where $\nu_{t}$ denotes the Clairaut constant of ${\widehat}{\gamma}_{t}$. By (\[prop6.4-1\]), $$\label{prop6.4-2} { d(\partial X, q) + d(q, \mu_{0}(0)) \ge \frac{\nu_{t}^{2}}{2} \int_{d(\partial X,\, q)}^{t} \frac{1}{m(t)^{2}}\,dt }_.$$ First, assume that $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies (\[prop6.4-con1\]). Then, it is clear from (\[prop6.4-2\]) that $${ \lim_{t \to \infty} \nu_{t} = 0 }_.$$ Hence, by (\[clairaut\]), we have $$\label{prop6.4-3} { \lim_{t \to \infty} \angle(\partial {\widetilde}{X}, {\widehat}{q}, {\widehat}{\mu}_{0} (t)) = \pi }_.$$ By (\[prop6.4-angle\]) and (\[prop6.4-3\]), $\gamma_{\infty} := \lim_{t \to \infty} \gamma_{t}$ is a ray emanating from $q$ such that $${ \angle\,(\gamma'_{\infty}(0), - \mu'_{1}(d(\partial X, q))) = \pi }_.$$ This implies that $q$ lies on a unique $\partial X$-segment. Therefore, by Lemma \[lem2009-03-03\], $q$ lies on a $\partial X$-ray. Now, it is clear from Lemma \[lem6.2\] that $\partial X$ is totally geodesic. Second, assume that $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies (\[prop6.4-con2\]). Then, there exists a divergent sequence $\{ t_{i} \}_{i \in {\ensuremath{\mathbb{N}}}}$ such that $$\label{prop6.4-4} { \lim_{t \to \infty} m(t_{i}) = 0 }_.$$ From (\[clairaut\]), we see $$\label{prop6.4-5} \nu_{i} \le m (t_{i}),$$ where $\nu_{i}$ denotes the Clairaut constant of ${\widehat}{\gamma}_{t_{i}}$. Hence, by (\[prop6.4-4\]) and (\[prop6.4-5\]), $$\liminf_{t \to \infty} \nu_{t} = 0$$ holds. Now, it is clear that there exist a limit geodesic $\gamma_{\infty}$ of $\{\gamma_{t_{i}}\}$ such that $\gamma_{\infty}$ is a ray emanating from $q$ and satisfies $\angle\,(\gamma'_{\infty}(0), - \mu'_{1}(d(\partial X, q))) = \pi$. Therefore, by Lemma \[lem2009-03-03\], $q$ lies on a $\partial X$-ray. ${\hfill \Box}$ By Proposition \[prop6.4\], there does not exist a cut point of $\partial X$. Therefore, it is clear that \[cor6.4\] If $({\widetilde}{X}, \partial {\widetilde}{X})$ satisfies

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ma'am." Eleven. Less than half of what we started the day with. No telling how many of the eleven were wounded. Probably most, though Mac's team seemed to move well, so maybe they'd avoided the worst of it. The two lift aircraft came in slower than the fighters, but still fast. The trick to spotting them was to look ahead of where you heard the noise. By the time you heard them, they'd already moved from that location. I tried to find one, only to watch a yellow-and-orange fireball light the sky. A split second later the loud _fwaaaap_ of a large pulse weapon cut through the night. More distortion of light and sound. A ship had exploded before we heard the weapon that killed it. One of the landing craft had disintegrated. Light streaked across the sky in golden fingers. Missiles. At least six, maybe more. Another flash, then another less than a second behind it. Both fighters hit, one explosion eclipsing the other. A sinking, queasy feeling grabbed at my gut. They'd just eliminated our rescue with a big pulse weapon and a bunch of surface-to-air missiles. But the enemy didn't have those weapons—they weren't supposed to, anyway. Those missiles hadn't been small shoulder-fired SAMs, either. They had high-end stuff. Dangerous. I put the implications of what just happened behind me for a minute and scanned the sky. We still had one transport left, and with our reduced numbers, they had space to carry us all out if they could get to us. Another missile streaked into the sky like a fiery sword. The second transport flung flares from its hull and dove hard, but the missile had locked in. A golden blossom of death lit the sky and the transport spun toward the ground, spitting flames. A quirk of fate set its descent almost directly toward the source of the missile that killed it. "Ejects," said Mac, softly so it didn't carry. I scanned the sky and found the pilots with my night-vision optics. "Got them. Looks like they both popped clear. You think anyone else popped? From the other birds?" The chutes drifted toward Cappa in a controlled fall. "Don't know, sir," said Mac. "I doubt it. They flashed pretty big." "Yeah," I said. Baxter stood and hurried over to me, taking a knee. "Sir, what the fuck do we do?" Her voice rose a few notes. "Call it in," I said. "Sir, the jammer. We've got no off-planet commo again." Shit. "They must have moved in a mobile." Even as I said it, I doubted it. The enemy had pulled back when the fighters attacked. Nothing could have survived that barrage. They had to be jamming the satellites directly. That meant a bigger problem, but one for another day. We had to live through this, first. My mind scrambled for a solution. "There's no way that Cappa Base doesn't know what's going on now." I kept my voice level, hoping it would help Baxter do the same. "They'll send help. Wait for the next ships to come into range, then signal them in. You'll know they're close, because they're going to blow the crap out of that anti-aircraft site before they get here, now that they know about it." "It will take at least twenty-five or thirty minutes until they arrive," she said. She was right, and we didn't have thirty minutes. With the ships down, the enemy would move back in. "Let's go," I said. "Where, sir?" she asked. "Anywhere but here. Let's not give them an easy target." "We should head for the downed pilots," said Mac. "Perfect," I answered. "They'll have beacons, not the markers we've got. Transmitters that broadcast without satellites. All the pilots do. And if there's one thing you can guarantee, it's that the squadron isn't going to leave their fellow pilots down here." "Yes, sir," said Baxter, her voice steady, the moment of indecision gone. She was going to make it in our business, assuming she lived through this fight. That's what the good ones did. If they panicked, they got over it fast. "Move now, two groups of four, three in the middle," radioed Baxter. "We've got tail," I told her. Mac grabbed two of the soldiers who came with him to round out our team and linked the others up with another element. We started moving fifteen seconds later, three wedges, our trailing group inverted so the point faced back. If the fighters hadn't destroyed the enemy in front of us, we'd know soon. And if we made it past that, I hoped that the downed pilots didn't shoot at us thinking we were enemy. We didn't have any way to speak to them, and trusting scared pilots on the ground was risky. Another problem for later. Even with night vision, the branches slapped against my face plate, and low scrub grabbed at my feet and ankles. It kept us to a quick walk, and we still made more noise than I'd have liked. _Thirty minutes_. Less than five minutes later, four rockets slammed the ground to our front, throwing dirt, rock, and branches, shaking our already wobbly legs. They knew we were moving. They had to. They only missed by a hundred meters. By unspoken accord, we picked up our pace. Someone might fall in a hole or smash a knee on a rock, but it beat being cut in half by hot metal. Another barrage ripped through the trees, off to the right this time, farther away. An enemy machine gun tore through the night, also off the mark. The bullets hunted through the woods, meandering slowly, looking for a target without knowing where to start. Recon by fire. They wanted us to shoot back. I flipped open the channel to tell everyone to hold their fire. Too late. The man beside me let off a three-round burst. "Cease fire." I tried to keep my voice calm on the net. No use yelling about it now. "I had his position marked," said the soldier who fired. She sounded confused more than defensive. "We don't want to give away _our_ position," I called over the net. "We need to move. Now." Two heavy weapons and at least a dozen smaller ones raked the ground around us, ripping chunks out of trees and flinging up dirt, flashing off of rocks. Without firing back, we had nothing to keep the enemy's head down. Even from three hundred meters, if they kept enough bullets flying, they'd get lucky soon enough. "Keep moving," I radioed. "My team will stop and pour down some fire for thirty seconds, then catch up." Mac flashed me a thumbs-up to show me that he heard. He grabbed one of the other soldiers and physically put her into position behind a head-sized rock. He put the other behind a tree. That didn't leave much cover for him or me, so we grabbed the ground and got as low as we could. "Fire when I do," I radioed. "Slow and steady. Thirty seconds, twenty rounds. Explosive if you've still got them. Pick targets if you can, if not, try to silence the bigger guns." I took a deep breath and silently counted to three for no particular reason. I squeezed my first shot off in the direction of one of the heavy guns, then fired three more in a pattern right around it. The staccato burst of my own team firing close by drowned out the sound of the enemy. Vaguely I sensed bullets getting closer. Something cracked into my left shoulder, wrenching my weapon from that hand. A burst of molten fire jolted my shoulder joint, then my whole arm went numb. I didn't think the bullet penetrated my armor, though I had no way to tell in the dark. The force of the bullet did enough, even with the protection I had from my gear. I shook my numb hand, trying to find some feeling. Belatedly, I rolled over twice to a new position in case someone had homed in on my location. Always have to remember the fundamentals. A dozen bullets ricocheted off the rock our soldier hid behind, throwing sparks into the air and momentarily screwing with my night optics. I aimed in the general direction of the fire with my one working arm and squeezed off half a dozen useless shots before rolling again. "Ten seconds until we move," I said. "Shoot 'em if you got 'em." The pops around me intensified. No fire came from behind the rock, so I crawled on my belly toward the soldier's position, pulling with my good arm. She lay still, her helmet shattered. I grabbed her and rolled her toward me, but I knew even before I finished moving her that we'd lost her. Too many cracks in the helmet, too many bullets. Shit. I didn't even know her name. I grabbed her ammo. "Let's go," I called. "We're just three. On my move." I leaped to my feet, not waiting to

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*Conflict of interest statement*. None declared. Supplementary Material ====================== ###### \[Supplementary Data\] We thank Dr Zhenbao Yu for valuable discussion and advice, Linhua Zhang, Meiqun Wu and Denis L'Abbe for technical assistances. [^1]: The names of siMVPs were designated according to their positions in 1.3kb-*MVP* cDNA clone. [^2]: Only the sense strand is shown. [^3]: HeLa cells were transfected with 60 ng p*EGFP*, 1.2 ng p*RLSV40* (*Rluc*) and 0.1nM siMVPs synthesized *in vitro*. Three independent assays each in triplicate were performed. The potency of siMVPs was calculated by the ratio of EGFP/*Rluc* against the control of unrelated siRNA (siHB1). You are here UFC 214: Lawler vs Cerrone Betting Odds I hope you like violence because Robbie Lawler and Donald Cerrone are scheduled to clash at UFC 214 in an all-action bout that has “fight of the year” written all over it. We haven’t seen Lawler since he dropped the welterweight title to Tyron Woodley last July while Cerrone is coming off a tough loss to Jorge Masvidal. ‘Ruthless’ Robbie Lawler opened as a -145 favorite with ‘Cowboy’ Cerrone coming back at +115. Assuming this line stays steady, this will be the first time Cerrone has entered a fight as an underdog since his title loss to Rafael dos Anjos in December 2015. Lawler bloomed late in his career, taking several years to accumulate experience that has been a valuable asset to his style. He is more crafty than flashy and looks to counter-strike with his fast, heavy hands when striking. Lawler is vicious in the clinch and his good takedown defense allows him to punish opponents who try to shoot. Cerrone wants to break down his opponent with a mixture of pace and vicious leg kicks. Very few fighters in the UFC can cut down an opponent the way that Cerrone can. The Denver, Colorado native is also a lethal submission specialist if the fight goes to the mat. The handicapping, sports odds information contained on this website is for entertainment purposes only. Please confirm the wagering regulations in your jurisdiction as they vary from state to state, province to province and country to country. Using this information to contravene any law or statute is prohibited. The site is not associated with nor is it endorsed by any professional or collegiate league, association or team. OddsShark does not target an audience under the age of 18. Please visit gambleaware.co.uk or gamcare.org.uk for guidelines on responsible gaming.###### Strengths and limitations of this study - This retrospective study reveals the first Australia-wide evidence on the relative safety of planned birth in hospital, a birth centre and at home. - It analyses linked data on the outcomes for women with uncomplicated pregnancies and their infants in all eight Australian states and territories. - Careful data screening eliminated most causes of obstetric complexity, resulting in three cohorts with equivalent levels of risk. - Inconsistency between state-based datasets limited the number of confounding variables available for analysis. - Insufficient data on changes in planned birth place prior to labour hampered identification of intrapartum transfers and analysis of the relationship between intended and actual place of birth. Introduction {#s1} ============ In Australia, most births occur in hospitals (97.5% in 2015), with some variation across the eight states and territories (for example, 91% in the Australian Capital Territory to 99% in Victoria).[@R1] Women with uncomplicated pregnancies and who are planning hospital births in the public health system receive antenatal care from hospital-based midwives and doctors, sometimes within continuity of care models and often in partnership with local general practitioners (GPs). Hospital midwives attend their labour and birth, with medical involvement as required or in line with local protocols. In the private health system (where 25% of births take place), women receive antenatal care from private obstetricians or midwives employed by obstetricians. Hospital midwives attend their labour and birth and the obstetrician attends during the labour and is usually at the birth.[@R2] There are some differences across Australia in the way care is provided, especially the local guidelines and the choices available to women. The availability of different models of care varies across the country. While most births take place in hospital labour wards or birth suites, a small proportion (1.8% nationally) take place in midwife-run birth centres.[@R1] In Australia these birth centres are typically co-located with hospitals (similar to alongside midwifery units in other countries) although a small number of stand-alone birth centres exist.[@R4] Birth centres typically provide midwifery continuity of care to women with uncomplicated pregnancies in a home-like environment and are well integrated into the health system. Less than 0.3% of Australian births take place at home, ranging from 0.1% of births in New South Wales to 0.6% in the Northern Territory.[@R1] Most planned home births are attended by midwives working in private practice, some of whom also attend women in birth centres and hospitals. The integration of private homebirth services varies across the country. A small number of hospitals and birth centres offer home births through the public health system.[@R6] An evaluation of the outcomes of publicly funded models providing homebirth showed that the rate of stillbirth and early neonatal mortality was low, at 1.7 per 1000 births. However, the sample size did not have sufficient power to generate a conclusion about safety.[@R7] We have conducted a systematic review to examine maternal and perinatal outcomes associated with planned place of birth for women with uncomplicated pregnancies in high-income countries.[@R8] In this analysis of 28 studies from 13 countries, women who planned hospital births had significantly higher rates of perineal trauma and instrumental/caesarean birth than those who planned other birth places. Overall, there was no significant difference in the odds of intrapartum stillbirth according to place of birth (compared with planned hospital births, planned homebirth: OR=0.94; 95% CI 0.76 to 1.17; planned birth centre OR=0.66; 95% CI 0.32 to 1.34) or in early neonatal deaths (planned home birth OR=1.00; 95% CI 0.78 to 1.27; planned birth centre 0.87; 95% CI 0.29 to 2.61). Previous Australian state-based studies into place of birth have showed variation in findings. In New South Wales (the most populous state accounting for around 30.9% of births),[@R9] women without pregnancy complications who planned a home or birth centre birth had significantly higher proportions of normal birth than those planning hospital births (home 97.4% vs birth centre 86.0% vs hospital 73.9%). There was no significant difference in neonatal mortality although the overall sample size (n=2 58 161, including only 742 planned home births), had insufficient power for these relatively rare outcomes. In South Australia (SA) (297 192 planned hospital births and 1141 (0.38%) planned home births), another study found lower intervention rates and equivalent perinatal death rates in home births compared with hospital births. However, the odds of an intrapartum fetal death were significantly higher among planned home births (two deaths in the planned home birth group; adjusted OR (AOR) 7.42; 95% CI 1.53 to 35.87). This study included some women with recognised risk factors in the home birth group including twins.[@R10] Large-scale studies in other countries show similar perinatal outcomes between births planned at home and in hospitals (and birth centres where these exist) with some differences for primiparous women.[@R11] There is less controversy about birth centres compared with homebirth. Data from Australian birth centres indicate lower rates of maternal morbidity,[@R15] intervention, preterm birth and low birth weight compared with hospital births for women with similar risk profiles.[@R16] One study identified no significant differences by birth place in perinatal mortality[@R16] and another reported lower perinatal mortality in birth centre births, although based on actual rather than intended birth place.[@R17] A smaller hospital-based study found no significant difference in caesarean section rates between the birth centre and labour ward for women with uncomplicated pregnancies.[@R18] Two other birth centre studies reported higher rates of spontaneous vaginal birth and lower rates of adverse infant outcomes (neonatal intensive care unit (NICU) admission, low birth weight) compared with hospital births.[@R19] The safety of place of birth continues to be questioned in Australia.[@R21] To generate evidence to assist policy makers, health practitioners and pregnant women and their families to make informed decisions about place of birth, we undertook a national study combining data from all eight Australian jurisdictions to examine the outcomes for women with uncomplicated pregnancies related to three different birth settings. This is the first national study on the comparative safety of different planned birth settings in Australia. Aim and objectives {#s1-1} ------------------ The study aimed to compare the perinatal and maternal outcomes for Australian women with uncomplicated pregnancies according to planned place of birth, that is, hospital labour wards, birth centres or at home. Outcomes investigated included normal labour and birth, mode of birth, interventions during labour

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){ref-type="fig"}). Further independence of ProQ from ProP is demonstrated by the fact that ProQ is still associated with ribosomes in the absence of *proP* and *proU* mRNAs ([Figure 5](#pone-0079656-g005){ref-type="fig"}). Though further studies are needed to definitively determine the function of the ribosomal association of ProQ, it is not unreasonable to propose a role for ProQ in translation initiation. Under non-dissociating conditions, we observe the highest concentration of ProQ in fractions corresponding to 70S and polysome species, but there is a modest, yet consistent, increase in signal under the peak corresponding to 30S particles, the first particle to bind during initiation ([Figure 1A](#pone-0079656-g001){ref-type="fig"}). This 30S localization is confirmed under dissociating conditions ([Figure 1B](#pone-0079656-g001){ref-type="fig"}). We present data showing that ProQ can bind tightly to mRNA *in vitro* ([Figure 4](#pone-0079656-g004){ref-type="fig"}), and mRNA integrity is necessary for robust ribosome association ([Figure 3](#pone-0079656-g003){ref-type="fig"}). Thus, ProQ is ideally positioned to function in translation initiation of its mRNA targets, perhaps by facilitating the interaction between 30S particles and these as-yet unidentified mRNAs. The authors wish to thank Dr. Titus Franzmann for training and technical assistance with tryptophan fluorescence experiments and Dr. Stefan Walter for assistance with ProQ-mRNA binding data analysis. [^1]: **Competing Interests:**The authors have declared that no competing interests exist. [^2]: Conceived and designed the experiments: DTS RZ. Performed the experiments: DTS RZ. Analyzed the data: DTS. Contributed reagents/materials/analysis tools: DTS. Wrote the manuscript: DTS. Critical reading and approval of the final manuscript: DTS RZ. Fitness recovery and compensatory evolution in natural mutant lines of C. elegans. Deleterious mutation accumulation plays a central role in evolutionary genetics, conservation biology, human health, and evolutionary medicine (e.g., methods of viral attenuation for live vaccines). It is therefore important to understand whether and how quickly populations with accumulated deleterious mutational loads can recover fitness through adaptive evolution. We used laboratory experimental evolution with four long-term mutation-accumulation (MA) lines of Caenorhabditis elegans nematodes to study the dynamics of such fitness evolution. We previously showed that when homozygous mutant populations are evolved in large population sizes, they can rapidly achieve wild-type fitness through the accumulation of new beneficial or compensatory epistatic mutations. Here, we expand this approach to demonstrate that when replicate lineages are initiated from the same mutant genotype, phenotypic evolution is only sometimes repeatable. MA genotypes that recovered ancestral fitness in the previous experiment did not always do so here. Further, the pattern of adaptive evolution in independently evolved replicates was contingent upon the MA genotype and varied among fitness-related traits. Our findings suggest that new beneficial mutations can drive rapid fitness evolution, but that the adaptive process is rendered somewhat unpredictable by its susceptibility to chance events and sensitivity to the evolutionary history of the starting population.[Intraoperative Optical Coherence Tomography - an Overview of Current Clinical Data for the Application in the Anterior and Posterior Segments]. Intraoperative optical coherence tomography (iOCT) represents another milestone in ocular imaging technologies. Now, for the first time, high resolution OCT images are available not only pre- or postoperatively, but also intraoperatively. In recent years, there have been significant advances in iOCT technology - from hand-held probes and mounted systems towards iOCT systems which are fully integrated into the surgical microscope and which provide seamless integration into the workflow. These systems offer high-resolution, intraoperative OCT scans in real-time and provide additional information on microstructures of the retina or the cornea. These findings may even lead to a modification of surgical strategies. Like any other new technology, iOCT technology still has some limitations, such as shadowing from instruments and the lack of eye tracking systems. Therefore, the current state of iOCT technology still requires some skill to track surgical maneuvers in real time. Further research and development will help to solve these limitations in the future. However, even if not required for all surgical procedures, iOCT imaging can already improve safety and control in many surgical procedures on the anterior and posterior segments. This has already been shown in several studies and case series. Particularly in the surgery of vitreomacular traction, peeling of epiretinal membranes (ERM peeling) and macular hole surgery, iOCT offers significant added value. It improves the visualisation of transparent structures and helps to avoid the usage of dyes. In addition the success of the surgical maneuvers can be investigated intraoperatively. In lamellar keratoplasty and glaucoma surgery too, iOCT improves precision and safety. Moreover, iOCT technology may help to achieve further insight into ocular pathologies and a better understanding of the impact of surgical maneuvers on visual rehabilitation. Further prospective studies are however required to evaluate the usefulness of iOCT in various surgical procedures on both, the anterior and posterior segments.Spengler wrote as if decline was inevitable, as if the cycle he described – in which each civilization experiences its spring, summer, autumn, winter – were as unavoidable as the spinning of the earth. Once societies pass their great creative stage and the logicians, rationalists, and bureaucrats arrive on the scene, there is no turning back. Having lost a sense of purpose, civilizations lurch outward to find meaning. They get caught up in a series of disastrous wars, propelled forward to doom by history’s cosmic beat, power for power’s sake, blood for blood’s. The big political news in the United States of America over the last few days is that the leading candidate for the Republican Party nomination for next year’s Presidential election, a business mogul by the name of Donald Trump, has called for a ban on Muslims being allowed into the United States. The mainstream Republican Party candidates and personalities have, by and large, denounced Trump’s bigoted call. He has even been referred to as a “fascist demagogue.” But, Trump’s lead in the polls derives from the fact that the things he has been saying, no matter how distasteful to more enlightened Americans, appeal to the Republican base. It may be said that what we now know as the United States began almost four hundred years ago with the arrival from Plymouth, England, of a sailing ship called the Mayflower north of Virginia on the northeastern coast of America. This was 1620 Anno Domini, and the passengers were English men and women who felt they were experiencing a religious persecution in England which they considered unbearable. They were called “Pilgrims,” also “Puritans.” They were Christians being persecuted by Christians. The majority population of what we now know as the continental United States at the time when the Pilgrims landed was, of course, Native American tribes. But, in 1565 the Spanish had established St. Augustine in what we now call Florida, St. Augustine being considered the oldest city in the United States. It would be interesting to establish when precisely it was that the United States became a majority white population. When the United States of America declared its independence from England in 1776, the U.S. was just thirteen former British colonies. Today, the United States consists of fifty two states and a much larger land mass than at independence in 1776. The United States did not acquire the so-called Louisiana territory from France until 1803, Napoleon Bonaparte having given up his Western Hemisphere ambitions and pretensions after the French were defeated in Haiti by Toussaint, Dessalines, and other former African slaves. This Louisiana territory is about two fifths of the present day United States. In 1776, again, almost all the area west of the Mississippi River was controlled by various Native American tribes. And, in the South and the Southwest, the Spanish were prominent from Florida through Texas and New Mexico all the way to Arizona and California. America, then, is a new phenomenon compared to Great Britain, Germany, France, and so on. Before I proceed, let me say this. Inside the bastions of pure white supremacy, Europeans like the Spanish and the Italians are not really considered “white.” This is partly because the North Africans were so powerful in places like modern Italy, Spain, and Portugal for so many centuries, beginning with Hannibal, I suppose, and extending all the way up to 1492, when the Moors were expelled from Spain after seven centuries of hegemony. The elite in the United States are called WASPs – White Anglo-Saxon Protestants. The Irish, Jewish, Italian, and other populations now part of America’s white majority, came from Europe, afterwards Eastern Europe, in waves of immigration which began taking place in the latter half of the nineteenth century. In America today, for whatever it’s worth, “white” is equated with “Christian,” hence there is a racial undertone to Donald Trump’s assault on Muslims. (In white America, Arabs are definitely not considered white.) You see what we are dealing with here. Now, at some point after World War II the United States essentially became an empire, insofar as its power and wealth were concerned, and today, in a bit of desperation, there are significant elements in the United States who want to declare the American empire a “white” empire, and, through Trump, they are declaring this to the world. As planet earth’s imperial superpower, the United States interacts with the world in various ways. Perhaps the most strateg

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the algorithm: the aim is to generate a stochastic representation of the ground-state wavefunction, which is then used to compute expectation values of observables. Statistical fluctuations are reduced with the help of a guiding wavefunction, whose free parameters are determined dynamically during the simulation. In order to keep the variance of observables finite as the simulation proceeds, it is necessary to simulate a population of $K$ [*walkers*]{} (field configurations at fixed time), and extrapolate the results to $K\to\infty$. We focus on the case $V = \lambda_2\phi^2 + \lambda_0\phi$; strong coupling always predicts supersymmetry breaking; weak coupling predicts unbroken supersymmetry for $\lambda_0<0$; according to Ref. [@Witten2], unbroken supersymmetry should be accompanied by a nonzero $\langle\phi\rangle$ (parity breaking). We presented preliminary results, obtained by GFMC, for intermediate couplings in Ref. [@lattice2001]; our aim is to extend the study towards the continuum limit and to larger lattices. Perturbative computations show that $$\lambda_2 \approx a \lambda_2^{\rm ren}, \quad \lambda_0 \approx a \lambda_0^{\rm ren} + a \lambda_2^{\rm ren}\frac{1}{2\pi}\ln\left(aM\right), \label{eq:evol2_L}$$ where $\lambda_i$ is the adimensional lattice bare coupling, $\lambda_i^{\rm ren}$ is the renormalized (continuum) coupling, with dimension of $m^1$, defined at the mass scale $M$, and $a$ is the lattice spacing. We study, as $\lambda_2\to 0$, the trajectory $$\lambda_0={\lambda_2\over2\pi}\,\ln(4\lambda_2), \label{eq:trajectory}$$ corresponding to a perturbative RG trajectory (\[eq:evol2\_L\]); the effect of $\lambda_0$ is small in the range we considered, therefore we expect Eq. (\[eq:trajectory\]) to be a reasonable approximation to a true RG trajectory. We estimate the correlation length from the exponential decay of the connected correlation function $G_d=\langle\phi_n\phi_{m}\rangle_c$ averaged over all $n,m$ pairs with $|m-n|=d$, excluding pairs for which $m$ or $n$ is closer to the border than (typically) 8. In our formulation, fermions are staggered and even/odd $d$ correspond to different channels. -8mm -8mm We begin with the discussion of the case $V=0.35\,\phi^2+0.02$, for which we have obtained the statistics of $4{\times}10^6$ GFMC iterations. The even-$d$ channel is plotted in Fig. \[fig:xieven,l2=0.35\]; it is very difficult to extract a correlation length, presumably because $\phi$ has a very small overlap with the lightest state of the channel, and the value of $\xi$ quoted in Fig. \[fig:xieven,l2=0.35\] should be considered tentative. The odd-$d$ channel, plotted in Fig. \[fig:xiodd,l2=0.35\], is much cleaner, and it is possible to estimate $\xi$ with a good precision. For the other values of $\lambda_2$, the situation is similar but with larger errors; we have a statistics of at least $10^6$ iterations, which we are increasing to $4{\times}10^6$. The values of $\xi_{\rm odd}$ follow nicely the expected behavior $\xi\propto1/\lambda_2,$ as shown in Fig. \[fig:xioddlog\]: the entire range $0.088\le\lambda_2\le0.35$ seem to be in the scaling region, with $\lambda_2=0.5$ a borderline case. The values of $\xi_{\rm even}$ have very large errors, and it is hard to draw any conclusion from them. -8mm We measure the ground state energy $E_0$ along the trajectory (\[eq:trajectory\]); the measurements have a very small statistical error, ranging from 1% for $\lambda_2=0.044$ (where $E_0/L\approx10^{-3}$) to 0.1% for $\lambda_2=0.5$. We extrapolate to $L\to\infty$ and $K\to\infty$ fitting $E_0/L$ to the form $${E_0/L} = {\cal E}_0\left(1 + {c_L/L} + {c_K/K}\right). \label{eq:E0/L}$$ $E_0/L$ is plotted in Fig. \[fig:E0log\]: it seems to behave $\propto\lambda_2^{5/3}$, while naïve scaling would predict $\propto\lambda_2^2$. The value of $E_0/L$ (disregarding this puzzling exponent) and the lack of any signal for a breakdown of parity (like a double-peaked distribution of $\phi$) strongly hint that the trajectory (\[eq:trajectory\]) belongs to the phase with broken supersymmetry and zero $\langle\phi\rangle$. We are repeating the computation for trajectories with smaller $\lambda_0$. -8mm [9]{} J. Kogut, L. I. Susskind, Phys. Rev. D11 (1975) 395; J. Kogut, Rev. Mod. Phys. 51 (1979) 659. W. von der Linden, Phys. Rept. 220 (1992) 53. M. Beccaria, M. Campostrini, A. Feo, Nucl. Phys. B (Proc. Suppl.) 106-107 (2002) 944. M. Beccaria, M. Campostrini, A. Feo, hep-lat/0109005. E. Witten, Nucl. Phys. B188 (1981) 513. E. Witten, Nucl. Phys. B202 (1982) 253. [^1]: Presented by M. Campostrini The Latest on the Con Man and His Victims (Fyre: The Greatest Party That Never Happened, Netflix) Note: This post was updated on Sept. 24, 2019: These days, when I’m not rewatching Forensic Files on TV, I’m restreaming Fyre: The Greatest Party That Never Happened on my MacBook. Happier times: Fyre investor Carola Jain, Billy McFarland, Jason Bell (not involved with Fyre), and Ja Rule You can see the Netflix Fyre documentary half a dozen times and pick up something new every time. Blue-eyed bandit. The 97-minute original production tells the excruciating story of a music festival founder who believed that a high-profile social media campaign would magically compensate for severe unpreparedness and underfunding. Billy McFarland promised ticket buyers private-jet transportation, ahi sliders, luxurious villas on a nirvana-like private island in the Bahamas, and performances by 10 major recording artists. The Fyre Festival failed on all accounts. Most of the well-to-do millennials who spent upward of $4,000 per person to experience a luxurious bacchanalia ended up receiving no-frills flights, sleeping on rain-soaked mattresses in FEMA tents on a gravelly construction site, scrounging for food, and listening to excuses from McFarland instead of performances by Blink-182 and Tyga. Infernal mess. In a way, even the locale for the festival didn’t exist. McFarland said he had purchased Pablo Escobar’s island, where organizers shot a promotional video featuring such supermodels as Emily Ratajkowski and Hailey Baldwin — who then publicized the upcoming event via Instagram — but the sale never actually happened. The organizers then arranged to have the festival on Great Exuma, a Bahamian island that isn’t private, so they photoshopped out parts that weren’t. Before Fyre, McFarland, then 25, probably imagined himself as the next under-30 entrepreneur headed for the Forbes 400 list. Note the FEMA tents on the Netflix film promo Card game. Described as charming, intelligent, and persuasive, the towering and slightly tubby New Jersey native first made a name for himself by establishing Magnises, a credit card whose fee included perks like discounted Beyoncé tickets and social events at a Manhattan townhouse. That venture, targeted at millennials, got off to an impressive start, then fizzled after not delivering on promises. But it didn’t get enough bad press to cloud McFarland’s image as a young visionary. It was the Fyre Festival flameout that exposed McFarland as a fraud for all the world to see. Virtually every major news media outlet covered the April 2017 disaster. Schadenfreude samba

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norms. The series expansion of a composition of fully matricial analytic functions {#sec13.10} --------------------------------------------------------------------------- This section records the fact that the noncommutative series expansion of a composition of fully matricial holomorphic maps coincides with the composition of the series. More precisely we have the following proposition. [**Proposition.**]{} [*Let $B(j)$ $(j = 1,2,3)$ be Banach spaces and let ${\Omega}(j)$ be affine fully matricial $B(j)$-sets containing the origin. Let further $g: {\Omega}(1) \to {\Omega}(2)$ and $f: {\Omega}(2) \to {\Omega}(3)$ be fully matricial holomorphic maps which send the origin to the origin. With the notations of [*\[sec13.9\]*]{} let $$\begin{aligned} {\alpha}_k &\in {{\mathcal L}}(B(1)^{{\widehat}{\otimes}k},\ B(2)), \\ {\beta}_k &\in {{\mathcal L}}(B(2)^{{\widehat}{\otimes}k},\ B(3)), \\ {\gamma}_k &: {{\mathcal L}}(B(1)^{{\widehat}{\otimes}k},\ B(3))\end{aligned}$$ be multilinear maps so that $$\begin{aligned} (d^kg_n)(O_n)[{\beta},\dots,{\beta}] &= k!{{\mathcal Z}}({\alpha}_k)_n({\beta}) \\ (d^kf_n)(O_n)[{\beta},\dots,{\beta}] &= k!{{\mathcal Z}}({\beta}_k)_n({\beta}) \\ (d^k(f_n \circ g_n))(O_n)[{\beta},\dots,{\beta}] &= k!{{\mathcal Z}}({\gamma}_k)_n({\beta}).\end{aligned}$$ Then we have $${\gamma}_k = \sum_{\substack{i_1 + \dots + i_l = k \\ i_j \ge 1}} {\beta}_l \circ ({\alpha}_{i_1} \otimes \dots \otimes {\alpha}_{i_l}).$$* ]{} The proposition follows in a straightforward way from the formulae for $d^k(f \circ g)_n$ in terms of the differentials of $f_n$ and $g_n$. Indeed we have $$(k!)^{-1} d^k(f \circ g)_n = \sum_{\substack{1 \le l \le k \\ i_1 + \dots + i_l = k \\ i_j \ge 1}} (l!i_1!\dots i_l!)^{-1} d^lf_n \circ (d^{i_1}g_n \otimes \dots \otimes d^{i_l}g_n)$$ when applied to $n$ copies of $${\beta}= \sum_{1 \le i, j \le n} e_{ij} \otimes b_{ij}$$ the left-hand side gives $$\sum_{1 \le p_1,\dots,p_{k+1} \le n} e_{p_1p_{k+1}} \otimes {\gamma}_k(b_{p_1p_2} \otimes \dots \otimes b_{p_kp_{k+1}})$$ while the right-hand side is $$\sum_{1 \le p_1,\dots,p_k \le n} e_{p_1p_{k+1}} \otimes S_{p_1\dots p_{k+1}}$$ where $$\begin{aligned} S_{p_1\dots p_{k+1}} = &\sum_{\substack{1 \le l \le k \\ i_1 + \dots + i_l = k \\ i_j \ge 1}} {\beta}_l({\alpha}_{i_1}(b_{p_1p_2} \otimes \dots \otimes b_{p_{i_1}p_{i_1+1}}) \cdots \\ &\otimes {\alpha}_{i_l}(b_{p_{i_1+\dots+i_{l-1}+1},p_{i_1+\dots+i_{l-1}+2}} \otimes \dots \otimes b_{p_{i_1+\dots+i_l},p_{i_1+\dots+i_l+1}})).\end{aligned}$$ Comparing the two proves the proposition. The Asymptotic Integral Formula for the Coefficients in the Unit Disk when $B = {{\mathfrak M}}_k$ {#sec14} ================================================================================================== {#sec14.1} We will build on the series expansion results to study stably matricial analytic functions in the unit disk. We will prove stably matricial analogues of the classical facts about density of polynomials and about the identification of the coefficients with the Fourier coefficients of the restriction to the unit circle. Here the role of the unit circle will be taken by the stably matricial unitary group ${{\mathcal U}}(B)$. Integration on ${{\mathcal U}}(B)$ will be the large $N$ limit of integrations with respect to Haar measures. [*We will assume that $B = {{\mathfrak M}}_k({{\mathbb C}})$ in [*\[sec14.3\]*]{} and [*\[sec14.4\]*]{}. The case $B = {{\mathbb C}}^k$ will be the subject of section*]{} \[sec16\]. Polynomial approximation for totally bounded analytic functions {#sec14.2} --------------------------------------------------------------- [**Definition.**]{} A $B_2$-valued stably matricial function $f$ on the stably matricial $B_1$-set $\Xi$, where $B_k$ are $C^*$-algebras is [*totally bounded*]{} if for some $t > 0$, $tf$ factors through the inclusion ${{\mathcal D}}_0^{cl}(B_2) \subset {{\mathfrak M}}(B_2)$. We define the uniform norm $\|f\|_{{\infty},\Xi}$ of $f$ to be the infimum of the $t^{-1}$ or equivalently to be $$\sup_{n \in {{\mathbb N}}} \sup_{{\beta}\in \Xi_n} \|f_n({\beta})\|$$ where ${{\mathfrak M}}_n(B_2)$ is endowed with the $C^*$-norm. If $\Xi = R{{\mathcal D}}_0(B_1)$ we shall also write $\|f\|_{{\infty},R}$ for $\|f\|_{{\infty},\Xi}$. If $\Xi$ is an open stably matricial set, we shall put $${{\mathbb H}}^{{\infty}}(\Xi) = \{f \in {{\mathcal A}}(\Xi) \mid \|f\|_{{\infty},\Xi} < {\infty}\}.$$ [**Proposition.**]{} [ *If $B$ is a finite-dimensional $C^*$-algebra and $f \in {{\mathbb H}}^{{\infty}}(R'{{\mathcal D}}_0(B))$ then given $0 < R < R'$ and ${\varepsilon}> 0$, there is $Z \in {{\mathcal Z}}(B^d)$ so that $$\|f-Z\|_{{\infty},R} < {\varepsilon}.$$* ]{} [**[*Proof.*]{}**]{} If $g: \{z \in {{\mathbb C}}\mid |z| < R'\} \to {{\mathcal X}}$, where ${{\mathcal X}}$ is a Banach space, is an analytic function and if $\sup_{|z| < R'} \|g(z)\| = M$ then we have the well-known bound $$\sup_{|z| \le R} \left\| g(z) - \sum_{0 \le n < N} c_nz^n\right\| \le M(R/R')^N(1-R/R')^{-1}$$ where $\sum_{n \ge 0} c_nz^n$ is the series expansion of $g$ at zero. Since the series expansion at the origin of $f_n$ restricted to any one-dimensional subspace of ${{\mathfrak M}}_n(B)$ is the series expansion of the restriction of $f_n$ to that subspace, we infer that if ${\beta}\in {{\mathfrak M}}_n(B)$, $\|{\beta}\| \le R$ then $$\begin{aligned} &\left\|f_n({\beta}) - f_1(0)I_n - \sum_{1 \le k < N} (k!)^{-1}d^kf_n(0_n)[{\beta},\dots,{\beta}]\right\| \\ &\le C(R/R')^N(1-R/R')^{-1}\end{aligned}$$ where $C$ is the uniform norm of $f$ on $R'{{\mathcal D}}_0(B)$. By Theorem \[sec13.8\] and Remark \[sec13.8\] this means that $$\|f-Z\|_{{\infty},R} \le C(R/R')^N(1-R/R')^{-1}$$ for a polynomial function $Z \in {{\mathbb Z}}(B^d)$. Choosing $N$ large enough the right-hand side will be $< {\varepsilon}$. The asymptotic integral formula for the coefficients {#sec14.3} ---------------------------------------------------- We precede the proof of the integral formula by some free probability preparations. [**Lemma.**]{} [ *Let $(A,{\varphi})$ be a noncommutative probability space and let $U \in A$ be an invertible element and let $1 \in M \subset A$ be a subalgebra of $A$, so that $M$ and $\{U,