[Purulent pericarditis and colonic infiltrating to Salmonella enteritidis complicated by acute intussusception in a case of IL-12Rβ1 deficiency]. 
IL-12 receptor β1 deficiency (IL-12Rβ1) predisposes patients to mycobacteria and Salmonella infections.  We report a case of IL-12Rβ1 deficiency with a fatal multi-resistant Salmonella enteritidis infection.  This boy was born after from a consanguineous marriage, and diagnosed as having a IL-12Rβ1 deficiency since the age of 3 months.  He presented with recurrent Salmonella enteritidis essentially digestive localization, complicated by purulent pericarditis at the same germ at the age of two and a half years.  At the age of 3, a colonic infiltration due to a Salmonella enteritidis resistant to antibiotics, was complicated by acute intussusception, and the child died.  The IL-12Rβ1 deficiency is considered as having a good prognosis, in contrast to what happened in our patient.  We review therapeutic issues in these patients.