CP2289, a new 5-HT3 receptor ligand: agonistic activities on gastroenteric motility. 
A new 5-HT3 receptor ligand, CP2289, was synthesized and pharmacologically tested.  Although CP2289 inhibited the Bezold-Jarisch reflex, it contracted the excised ileal muscle of mice, rats and guinea pigs.  This response may reflect a partial agonist character of CP2289 in the gut.  In vivo antiemetic and gastric emptying tests gave similar results.