im from england where the gun laws are tight but i own a 22-250 rem vssf and i varmint hunt love long range lets know some of your loads one of mine is 38g of 380 with 52g a max ... all the very best ... mark t

I'm going to assume you mean, 38.0grains of H-380 powder with a 52 grain bullet..? 

Back when Mr. Hodgdon first got a hold of a new surplus powder, yet unnamed, he worked up a load in his 22-250 of 38 grains with a 52 grain bullet.  He was so impressed with the accuracy of this load he called this surplus powder H-380..

As for reloading the 22-250, it is virtually wide open as far as what any one rifle will shoot well, and you will get a lot of different suggestions. 

The rifles I have worked with, and my own liked these powders the best with 52-55grain bullets;

To answer directly, mine is 35.5 IMR 4895, Sierra 1400 (53 HP match flat base).  This is in a Remington 788 plain Jane, except floated, and polished.  Groups 0.5" day in day out.  Only load I have that will do this well. 

I'd like to hear from folks who have used these 22 match bullets on varmints, up to and including coyotes.  Sierra goes out of their way to unrecommend matchking bullets for hunting, but some use these I think.  How do they perform on critters? 
Thanks

Try the original Speer 52 gr.  hollowpoint over 34.5 of IMR 4895.  This is max.  so work up; it has explosive tendencies on small targets.  CB. 

__________________
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Beware the man that only owns one gun; he probably knows how to use it. 
I just hope my ship comes in before my dock rots. 

Getting the COL set to my Rem 700 chamber so I was only .010" off the lands helped the most.  If i use the factory loading manual COL specs, I was jumping the bullet almost .100" in the Remington chamber.  CRAZY!!!!!!! 

In general, rifles that chamber for the .22-250 have a twist rate that doesn't bode well for extremely light nor heavy bullets.  That's why the general consensus is 50 to maybe low 60 grainers work best. 

I'm still happily searching for the absolute best pet load in my rifle.  So far, Reloader 15, or 7 pushing a 52gr.  Sierra MatchKing has provided good results.  I'm still fine tuning the powder load. 

My next powder is Reloader 10x.  This has JUST come out by Alliant.  They claim that the powder is specifically designed for .22-250 and .223 cartridges.  Soon, I'll find out if it's the cat's meow...

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If it were up to me, the word "got" would be deleted from the English language. 

the sierra matchking bullets don't expand well.  that is why they are not suggested for game.  the tip is designed for accuracy.  As they don't expand well they don't blow big holes in varmint.  They still die, it just takes a bit longer. 

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